Dissertations / Theses on the topic 'Female stress urinary incontinence'
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Pagorek, Stacey. "PREVALENCE OF SPORTS-RELATED STRESS URINARY INCONTINENCE IN THE FEMALE COLLEGIATE ATHLETE." UKnowledge, 2019. https://uknowledge.uky.edu/rehabsci_etds/57.
Full textAbdel-Fattah, Mohamed. "Evaluation of transobturator tension free vaginal tapes in management of female urodynamic stress incontinence." Thesis, University of Aberdeen, 2015. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=230504.
Full textMostafa, Alyaa. "Evaluation of single incision mini-slings in surgical management of female stress urinary incontinence." Thesis, University of Aberdeen, 2014. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=217882.
Full textWeber, Lebrun Emily Elise. "Factors Associated with Subjective Improvement Following Midurethral Sling Procedures for Stress Urinary Incontinence: A Masters Thesis." eScholarship@UMMS, 2010. https://escholarship.umassmed.edu/gsbs_diss/466.
Full textValpas, A. (Antti). "Evaluation of laparoscopic colposuspension and the tension-free vaginal tape procedure in the surgical treatment of female stress urinary incontinence." Doctoral thesis, University of Oulu, 2005. http://urn.fi/urn:isbn:9514278275.
Full textWahlström, Gunilla, and Kerstin Jonsson. "Yngre kvinnors upplevelse av hur urinläckage påverkar livssituationen." Thesis, Mid Sweden University, Mid Sweden University, Mid Sweden University, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-9770.
Full textBackground: Among young women vary the presence of urinary leakage between 28-80% depending on the study and the sport practiced. Poor support in the upper part of the urethra and urinary bladder base is considered the common cause of stress urinary incontinence. Supports are given by the pelvic floor muscles and the key muscles to prevent incontinence. Urinary leakage occurs more frequent in women who engaged in sports that provide a high abdominal pressure. Pelvic floor training is considered to be an effective and safe method to treat stress urinary incontinence and is recommended in the literature as the first treatment action. Aim: To examine young active women's experience of urinary incontinence affects their lives. Method: A qualitative design with tape-recorded interviews and semi-structured open questions were used as data collection method. A strategic selection was made. Six young active elite sportswomen interviewed. A qualitative content analysis was conducted. Results: Four categories were identified: manageable, social limitations, emotional and communication. Main findings shows that young women do not talk about urinary leakage as a problem, they have different ways to cope. Women experience a fear of urinary leakage shall be affected without prior notice and to lose control. The risk of urinary leakage gives concentration difficulties in training. The study shows a great lack of information. Weighted understanding: Among young women, there may be a risk that they are more affected by urinary leakage than middle-aged and older women, in terms of their experience of urinary leakage and leak impact on their lives. This in view of the ideals which today makes high demands and is difficult to live up to. Women get often their first information on the basin floor exercise to prevent urinary leakage at childbirth. This information should take place earlier.
Bakgrund: Hos unga elitidrottare varierar förekomsten av urinläckage mellan 28-80 % beroende på studie och vilken sport som utövas. Dåligt stöd i övre delen av urinröret och urinblåsans botten anses vara den valigaste orsaken till ansträngningsinkontinens. Stödet ges av bäckenbottenmuskulaturen och dess viktiga muskler för att förhindra inkontinens. Urinläckage förekommer oftare hos kvinnor som utövar sporter som ger ett högt buktryck. Bäckenbottenträning anses vara en effektiv och säker metod för att behandla ansträngningsinkontinens och rekommenderas i litteraturen som första behandlingsåtgärd. Syfte: Att undersöka yngre aktiva idrottande kvinnors upplevelse av om urininkontinens påverkar deras livssituation. Metod: En kvalitativ metod med bandade intervjuer och halvstrukturerade öppna frågor användes som datainsamlingsmetod. Ett strategiskt urval gjordes. Sex yngre kvinnliga aktiva elitidrottare intervjuades. En kvalitativ innehålls analys utfördes. Resultat: Fyra kategorier identifierades: Hanterbarhet, sociala begränsningar, Emotionellt och kommunikation. Huvudesultatet visar att yngre kvinnor inte pratar om urinläckage som ett problem, de hade olika sätt att hantera situationen. Kvinnorna upplevde en rädsla för att urinläckage skulle ske utan förvarning och för att tappa kontrollen. Risk för urinläckage gav koncentrationssvårigheter vid träning. Studien visar en stor informationsbrist. Sammanvägd förståelse: Hos yngre kvinnor kan det finnas en risk för att de påverkas mer av urinläckage än medelålders och äldre kvinnor, när det gäller upplevelsen av urinläckage och läckagets påverkan på livssituationen. Detta med tanke på de ideal som idag ställer stora krav och är svåra att leva upp till. Kvinnor får oftast sin första information om bäcken botten träning för att förebygga urinläckage vid barnafödande. Denna information bör ske tidigare.
Czyrnyj, Catriona. "UROKIN: A Novel Software for Kinematic Analysis of Urogenital Motion Using Transperineal Ultrasound Imaging." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/36147.
Full textOremus, Mark 1968. "Surgery versus collagen to treat female stress urinary incontinence : physician beliefs and requirements for treatment & a modeled cost-effectiveness analysis." Thesis, McGill University, 2000. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=30719.
Full textA physician survey was conducted to help verify the SCIT investigators' consensus estimate. Respondents on average believed surgery was more efficacious than collagen, and they generally had stronger beliefs in the ability of surgery to meet their requirements for remaining the first line treatment for SUI. However, on average, respondents indicated a willingness to use collagen if it was at most approximately 23% less efficacious than surgery. The survey also provided baseline data for future research into how SCIT's results may or may not play a role in changing the views of clinicians.
The cost-effectiveness analysis was based on a risk-benefit model (decision-tree) that delineated the success rates, side-effects and complication rates of both surgery and collagen. Probabilities from the physician survey and the published literature were used in the model. Collagen was found to be less costly than surgery, but also less efficacious. Until more is known about collagen's long-term durability, the injection material will probably not gain coverage under Canada's provincial health insurance plans.
Oremus, Mark. "Surgery versus collagen to treat female stress urinary incontinence, physician beliefs and requirements for treatment & a modeled cost-effectiveness analysis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0034/MQ64424.pdf.
Full textHoşcan, Burak Perk Hakkı. "Stres üriner inkontinans tedavisi tedavisinde ekstrakorporeal manyetik innervasyon /." Isparta : SDÜ Tıp Fakültesi, 2004. http://tez.sdu.edu.tr/Tezler/TT00199.pdf.
Full textSchmidt, Adriana Prato. "Tratamento conservador da incontinência urinária de esforço feminina : estudo comparativo entre reeducação vesical e treinamento da musculatura do assoalho pélvico com biofeedback." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/174826.
Full textObjective: To compare the effect of pelvic exercises combined with biofeedback, against bladder training, using questionnaires on symptoms, quality of life, and sexual function. Methods: Randomized clinical trial. Women over the age of 18 with stress urinary incontinence, but without genital prolapse, were recruited at a urogynecology clinic and assigned to bladder training or pelvic floor restoration at home with biofeedback. Results for muscle strength and symptoms, quality of life, and sexual function questionnaires were compared after 3 months of physiotherapist-supervised treatment. Results: Fourteen patients in each group were analyzed at the end of the study. Both groups exhibited improved results for number of daily leakages (P<0.001), nighttime micturitions (P<0.002) and symptoms (P<0.001). For sexual function, there were no individual or intragroup differences. Some quality of life domains were significantly better in the bladder training patients, but perceived general health did not change significantly and did not differ between the BT (P=0.157) and BIO (P=0.795) groups. Improvements in perineal contraction were not correlated with increased muscle strength (rs=0.428 P=0.144). Conclusion: The two methods had equivalent results, but larger patient samples could change certain findings. It remains a challenge to develop technologies to improve patients’ motivation and adherence to conservative treatment. Registration: Plataforma ReBec (Brazilian Clinical Trials Register - http://www.ensaiosclinicos.gov.br/). Reference code REQ:7854.
Poza, Barrasús José Luis. "Estudio de cohortes prospectivo del tratamiento quirúrgico de la incontinencia urinaria de esfuerzo femenina mediante bandas suburetrales transobturadoras." Doctoral thesis, Universitat Autònoma de Barcelona, 2020. http://hdl.handle.net/10803/671294.
Full textEl objetivo principal de este estudio es conocer la eficacia y seguridad de la TOT a largo plazo, 10 años. Como objetivo secundario se ha establecido analizar los factores de riesgo que pueden influir en el resultado y complicaciones de la técnica quirúrgica. Material y métodos: Estudio de cohorte prospectivo de 10 años de duración, de las pacientes intervenidas por IUE mediante TOT, desde marzo de 2004 hasta diciembre de 2006, en la Unidad de Suelo Pélvico del Servicio de Ginecología del Hospital Universitario Vall d’Hebron. Un total de 565 pacientes fueron finalmente incluidas en el estudio. Los resultados de la cirugía incluyen factores objetivos y subjetivos, y se dividieron en: Curación, Mejoría, y Fallo. Las complicaciones se consideraron en 3 momentos: Intraoperatorias, A corto plazo (< 1 mes posterior a la cirugía), y a largo plazo (en cualquier momento del control postoperatorio > a 1 mes de la cirugía). Los factores de riesgo analizados han sido: Edad; IMC; Cirugía previa por IUE; Cirugía asociada para la corrección del POP; Diagnóstico urodinámico de la IUE; Vía de inserción de la TOT; y cirujano que realizaba la intervención. La incidencia de fallos global se analizó mediante curvas de supervivencia de Kaplan-Meier. La influencia de los factores de riesgo sobre los resultados o las complicaciones se analizaron mediante regresión logística univariable y multivariable. Las comparaciones de las variables categóricas se realizaron mediante test de X2 o test exacto de Fisher. Resultados: A último control la curación-mejoría fue de un 78%; Fallo por IUE un 8,8%; y Fallo por IUU un 13,3%. La probabilidad de que una paciente permanezca curada o mejorada tras la TOT es de un 83,8% al primer año; de un 77,6% al 5º año; y de un 73,2% al 10º año. El fallo por IUE se detecta sobre todo durante el primer año posterior a la intervención, permaneciendo estable durante los siguientes años. Los factores de riesgo para fallo fueron: Edad > 70 años (HR 2,42) [C.I.95% 1,24-4,75]; Obesidad II (HR 2,31) [C.I.95% 1,14-4,69] y Obesidad III (HR 3,36) [C.I.95% 1,32-8,52]; y antecedente de cirugía previa por IUE (HR 1,36) [C.I.95% 1,13-1,63]. La Incontinencia urinaria oculta actuó como factor protector para fallo (HR 0,11) [C.I.95% 0,32-0,37]. La incidencia de complicaciones detectadas en las pacientes fue: 4,80% intraoperatorias; 19,30% postoperatorias precoces (mayoritariamente retenciones urinarias en la primera semana posterior a la cirugía); y un 4,1% de complicaciones tardías (1,76% de erosión-exposición, y 2,47% de secciones por disfunción de vaciado vesical). Los factores de riesgo asociados a las complicaciones postoperatorias inmediatas han sido: la cirugía asociada por POP (OR 1,75) [C.I.95% 1,10-2,78], y la vía de inserción de la TOT (OR 1,86) [1,22-2,85]. No se han detectado factores de riesgo asociados a la complicaciones intraoperatorias o postoperatorias tardías. Un 34,69% de las pacientes con fallo por IUE desearon nueva cirugía, a las que se les realizó una banda suburetral retropubiana (TVT); los resultados de la segunda cirugía fueron de: Curación-mejoría en el 58,8% y Fallo por IUE en el 41,2%. No se han encontrado diferencias estadísticamente significativas al comparar los grupos de pacientes con fallo por IUE reintervenidas o no, ni entre los grupos de pacientes con fallo por IUE y fallo por IUU.
Material and methods: It is a 10-year prospective cohort study, of female patients who have undergone TOT surgical procedure because of a SUI, from March 2004 to December 2006, in the Pelvic Floor Unit from Vall d'Hebron University Hospital. A total of 565 patients were finally included in the study. The results from the surgery include objective and subjective items which were divided into: total healing, improvement and failure. Surgical complications have been considered at three different times: intraoperatively, short-term (<1 month after surgery) and long-term (at any time after the first month postoperatively). The risk factors analyzed included are: age, BMI, previous SUI surgeries, associated genital prolapsed surgery, urodynamics diagnosis of SUI, sling type of insertion route and surgeon who performed the intervention. Overall failure incidence was analyzed using Kaplan-Meier survival curves. The influence of risk factors on outcomes and complications was analyzed using univariate and multivariate logistic regression. Categorical variables were compared based on the X2 test or Fisher's exact test. Results At the last follow-up, the cure-improvement rate was 78%; SUI failure rate was 8.8% and UUI failure rate was 13.3%. The probability that a patient might remain healed or improved after the TOT insertion is 83.8% the first year, 77.6% until the 5th year and 73.2% ten years after the surgery. Failure, because of persistent SUI, is detected in most of the cases during the first year after the TOT insertion and it remains stable during the following years. The risk factors to present a failure are the following: age> 70 years (HR 2.42) [C.I.95% 1.24-4.75], obesity II (HR 2.31) [C.I.95% 1.14-4.69] and Obesity III (HR 3.36) [C.I.95% 1.32-8.52], and a history of previous SUI surgery (HR 1.36) [C.I.95% 1.13-1.63]. Hidden urinary incontinence (UI) shows to act as a protective factor for failure (HR 0.11) [C.I.95% 0.32-0.37]. The complication rate detected in the patients is: 4.80% intraoperative, 19.30% early postoperatively (mainly urinary retention during the first week) and 4.1% late complication rate (1.76% erosion-exposure, and 2.47% sections due to bladder emptying dysfunction). The risk factors associated with immediate postoperative complications demonstrated are these surgeries which associated prolapse surgery (OR 1.75) [95% CI 1.10-2.78] and the route of TOT insertion (OR 1.86 ) [1.22-2.85]. No other risk factors have been found to be associated with intra or postoperative complications. Meanwhile, a 34.69% of the patients who have suffered from a SUI failure have requested a second new surgery, considering the best option a retropubic tension-free vaginal Tape (TVT). Finally, the results obtained from this second sling surgery are a 58.8% healing-improvement and 41.2% SUI failure. No statistically significant differences were found between the groups of patients who suffered from a SUI failure compared to the ones who suffered from a UUI failure. When we focused on SUI failure, there is no differences statistically significant between those who had received a second surgery compared to those who didn’t. Conclusions: In conclusion, the TOT surgery has been demonstrated widely to be an effective and safe technique in our group of patients. Age, obesity grade II or III and a previous history of SUI surgery, seem to play as risk factors to suffer from a TOT failure; while, on the other hand, hidden UI acts as a protective factor. Only 34% of our patients who had reported a SUI failure requested a second surgery.
Mummery, Christine C. "Efficacy of physiotherapy treatment for female urinary incontinence." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0020/MQ47075.pdf.
Full textKhullar, Vikram. "Ultrasound imaging of the female lower urinary tract." Thesis, King's College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391595.
Full textSpirka, Thomas A. "Finite Element Modeling of Stress Urinary Incontinence Mechanics." Cleveland State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=csu1291495865.
Full textQuinn, Martin. "Vaginal ultrasound of the lower urinary tract." Thesis, University of Bristol, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240026.
Full textCutone, Benjamin. "Female urinary incontinence and treatment rates among a Medicare population." Thesis, Boston University, 2012. https://hdl.handle.net/2144/12340.
Full textIntroduction and Hypothesis: The objective ofthis study was to determine the treatment rates of urinary incontinence (UI) in women 65 years old and older by education, poverty, and socioeconomic status (SES). Additionally, it was investigated ifhaving a discussion with a health care provider about UI had any effect on treatment rates. Methods: The publicly available 2007-2009 Medicare Health Outcome Survey data was examined in regards to four items that query about UI. All women 65 years old and older who provided data on UI and level of education were included in the analysis. United States Census Bureau data were used to establish poverty and SES variables. Results: In total, 87,805 women met inclusion criteria and 43.2% reported experiencing some UI in the past 6-months with only 28.6% receiving any treatment for UI. Women with a college education who self-reported either a "small" or "big" UI problem were more likely to receive treatment for their UI (OR = 0.84 (95% CI 0.79, 0.89)) and (OR= 0.77 (95% CI 0.69, 0.86). Women with a college education and any magnitude ofUI were also more likely to discuss their UI problem with a health care provider (OR = 0.93 (95% CI 0.88, 0.97)) and (OR= 0.80 (95% CI 0.72, 0.89)). For women with a small UI problem, a discussion with a provider was most impactful in regards to treatment for women without a college education. For women with a big UI problem, a discussion was most beneficial to treatment for women with a college education. Conclusion: UI is a prevalent condition among women 65 years old and older. Women without a college education are disadvantaged in regards to receiving any treatment for UI. Treatment rates may be improved among less educated women if providers initiate discussions regarding UI during the clinical encounter.
Berglund, Anna-Lena. "A holistic view of urinary stress incontinence in women." Doctoral thesis, Umeå universitet, Obstetrik och gynekologi, 1995. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-96892.
Full textDiss. (sammanfattning) Umeå : Umeå universitet, 1995
digitalisering@umu
Pierson, Wanda Jane. "A study of the effect of stress incontinence and bladder retraining on older women's perceived self-esteem." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/27730.
Full textApplied Science, Faculty of
Nursing, School of
Graduate
Hägglund, Doris. "Att leva med urinläckage : en longitudinell populationsstudie om livskvalitet hos kvinnor och hur de hanterar sitt urinläckage /." Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2002. http://publications.uu.se/uu/fulltext/nbn_se_uu_diva-2542.pdf.
Full textBalog, Brian Michael. "Brain-Derived Neurotrophic Factor Mediates Recovery from Stress Urinary Incontinence." University of Akron / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=akron1602113592326106.
Full textGarley, Ailyn. "A case series to pilot cognitive behaviour therapy for female urinary incontinence." Thesis, Lancaster University, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422963.
Full textMcNally, Donal Stewart. "Pressure measurement in the investigation and treatment of urinary stress incontinence." Thesis, University of Exeter, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.253561.
Full textDragomir, Anca Dana Schroeder Jane C. "Uterine location of leiomyomata risk factors and relation to stress urinary incontinence /." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1223.
Full textTitle from electronic title page (viewed Mar. 26, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Epidemiology." Discipline: Epidemiology; Department/School: Public Health.
Wise, Brian George. "A clinical evaluation of maximal electrical stimulation in the management of female urinary incontinence." Thesis, King's College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362656.
Full textJackson, Simon. "Oestrogen supplementation in postmenopausal urinary stress incontinence : effect secondary to altered collagen pathophysiology?" Thesis, University of Bristol, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390374.
Full textTegerstedt, Gunilla. "Clinical and epidemiological aspects of pelvic floor dysfunction /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-065-6/.
Full textMurray, A. "A critical study of the application of the fluid bridge test before, during and after surgery for stress incontinence in women." Thesis, University of Liverpool, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384350.
Full textNyyssönen, V. (Virva). "Transvaginal mesh-augmented procedures in gynecology:outcomes after female urinary incontinence and pelvic organ prolapse surgery." Doctoral thesis, Oulun yliopisto, 2014. http://urn.fi/urn:isbn:9789526205632.
Full textTiivistelmä Virtsankarkailu ja emättimen monimuotoiset laskeumat ovat naisilla yleisiä. Näitä vaivoja perinteisillä leikkaustekniikoilla hoidettaessa leikkaustulokset ovat olleet epätyydyttäviä sekä tehon että komplikaatioiden ilmaantuvuuden osalta. Ongelmaa on yritetty ratkaista synteettisien verkkojen avulla, mutta verkkojen käytön myötä niihin on havaittu liittyvän myös ongelmia. Tilannetta hankaloittaa myös erilaisten verkkomateriaalien, tekniikoiden ja instrumentaatioiden runsaslukuisuus. Tässä tutkimuksessa selvitettiin neljän rakenteeltaan erilaisen polypropyleenistä valmistetun verkon turvallisuutta ja komplikaatioiden esiintyvyyttä hoidettaessa verkkoavusteisesti naisen virtsankarkailua ja emättimen pohjukan tai emättimen takaseinämän laskeumaa. Erityisenä kiinnostuksen kohteena olivat verkkoihin liittyvät eroosiot. Virtsankarkailun hoidon subjektiivinen teho ja potilastyytyväisyys selvitettiin käytettäessä tension-free vaginal tape- (TVT) ja transobturator tape (TOT) -tekniikoita. Laskeumien hoidon objektiivinen ja subjektiivinen teho arvioitiin käytettäessä posterior intravaginal sling- (PIVS) ja Elevate®Posterior -tekniikoita. Verkon eroosioiden ilmaantuvuus vaihteli rakenteeltaan erilaisten verkkojen välillä siten, että tiivistä mikroporoottista multifilamenttinauhaa käytettäessä eroosioiden ilmaantuvuus oli 16–25 %, kun taas kevyttä makroporoottista monofilamenttiverkkoa käytettäessä eroosioprosentti oli 0.9. TVT-menetelmällä saavutettiin 84 %:n ja TOT menetelmällä 80 %:n subjektiivinen teho. TVT-potilaista hoitoon tyytyväisiä oli 79 % ja TOT-potilaista 74 %. Posteriorinen IVS saavutti vain 69 %:n objektiivisen tehon pohjukan laskeuman hoidossa. Potilastyytyväisyys oli samaa luokkaa, 62 %. Sen sijaan Elevate®Posterior-menetelmää käytettäessä saavutettiin käytetystä tehon määritelmästä riippuen 84–98 %:n objektiivinen teho. Subjektiivinen teho tällä menetelmällä oli 86 %. Tämän tutkimuksen perusteella tiiviin mikroporoottisen multifilamenttiverkon käyttöön liittyvä verkkoeroosioiden määrä on sietämättömän suuri. Vakiintuneiden TVT- ja TOT-menetelmien subjektiivinen teho ja potilastyytyväisyys ovat hyväksyttäviä. PIVS-metodia käytettäessä sekä objektiivinen että subjektiivinen tulos on huono, kun taas Elevate®Posterior-menetelmän ja siinä käytetyn kevyen verkon käytöstä saadut tulokset ovat lupaavia
Sjöström, Malin. "Internet-based treatment of stress urinary incontinence : treatment outcome, patient satisfaction, and cost-effectiveness." Doctoral thesis, Umeå universitet, Allmänmedicin, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-84405.
Full textYip, Clare. "The contribution of pelvic muscle and ligament weaknesses to the development of stress urinary incontinence." Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/37905.
Full textGill, Bradley Cameron. "Neurotrophin Therapy Improves Recovery from Postpartum Stress Urinary Incontinence Following Simulated Childbirth Injury in Rats." Case Western Reserve University School of Graduate Studies / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=case1336054611.
Full textBrooks, Kaylee. "Characteristics Predictive of Successful Pelvic Floor Muscle Training Outcomes Among Women with Stress Urinary Incontinence." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/36667.
Full textAngelini, Kimberly. "A Cross-sectional Exploration of Lower Urinary Tract Storage Symptoms Among a Sample of Female Undergraduate College Students." Thesis, Boston College, 2018. http://hdl.handle.net/2345/bc-ir:108091.
Full textLower urinary tract (LUTS) storage symptoms, including overactive bladder (OAB) and urinary incontinence (UI), are common conditions among women with significant health and economic consequences. Much of the existing literature on LUTS focuses on older, often postmenopausal women, and there is limited research available about prevalence, incidence and severity of LUTS in young women. For many young women in the United States, the period from the late teens through early twenties coincides with the period of emerging adulthood and college enrollment. The unique factors influencing women at this stage of development may be influential in understanding prevalence and correlates of OAB and UI later in the life-course. The purpose of this cross-sectional descriptive survey-based study was to explore and describe the experience of urinary storage symptoms, specifically OAB and UI, among female undergraduate college students, and to identify associated factors. Qualtrics online platform was used to create and distribute the survey to a sample of 1,800 female college undergraduate students at a private Catholic university in the northeast. Two instruments previously used to assess LUTS, the ICIQ-FLUTS and LUTS Tool, were combined into the Urinary Symptoms Scale with a one-week recall. Twelve items assessed LUTS storage symptoms of OAB and UI. The final sample consisted of 456 female undergraduate college students with a mean age of 20.3-years-old. The sample was predominantly White non-Hispanic. Most commonly reported symptoms included urgency (47.6%), frequency (52.6%), urinary incontinence (21.3%), stress urinary incontinence (28.8%), and urge urinary incontinence (16.4%). Total severity scores were low and highly skewed towards the lower range (M = 3.31; SD = 3.91). Participants with symptoms, most commonly reported experiencing symptoms rarely or sometimes during the past week. Perceived bother from urinary symptoms mean scores were low (M = 1.77) but extended the full range on a 0 to 10 scale. In this study, perceived bother from urinary symptoms as well as perceived impact of urinary symptoms on activities of daily life (ADLs) were significantly associated with care-seeking and use of self-management strategies. Interestingly, LUTS storage symptom severity was not significantly associated with care-seeking, but it was related to use of self-management strategies in this population. Perception of overall health, history of constipation/IBS, sexual activity, delayed toileting behaviors, and premature toileting behaviors were significant in multivariate analyses when controlling for other factors. Further research on the relationship of these factors and LUTS storage symptoms is needed. This study represented a first step in understanding college women’s experiences with LUTS storage symptoms and identifying the unique personal, behavioral and environmental factors associated with LUTS. The study found that OAB and UI symptoms are common among female college undergraduates. In addition, a number of personal and behavioral factors were found to be associated with LUTS storage symptoms. Given that many health-related behaviors established during college years may persist later in adulthood, identifying experiences and influences of young women’s LUTS storage symptoms is important in informing future research and practice recommendations
Thesis (PhD) — Boston College, 2018
Submitted to: Boston College. Connell School of Nursing
Discipline: Nursing
Lord, Helen Elizabeth. "A randomised controlled equivalence trial comparing tension-free vaginal tape (TVT) with suprapubic urethral support sling (SPARC)." University of Western Australia. Faculty of Medicine and Dentistry and Health Sciences, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0086.
Full textPires, Telma Filipa Rodrigues Pereira. "Effects of pelvic floor muscles training on prevention and treatment of stress urinary incontinence in pregnant." Master's thesis, Universidade de Aveiro, 2015. http://hdl.handle.net/10773/16541.
Full textIntroduction: Stress urinary incontinence (SUI) is the most common type of urinary incontinence (UI) in pregnant women and is known to have detrimental effects on the quality of life (QoL). Pelvic floor muscle training (PFMT) is considered the first-line treatment and prevention of SUI in pregnant women. Since there are few randomized controlled trial studies (RCT) in this population, it is important to check the effectiveness of another randomized protocol of the PFMT. Objectives: This study aimed to verify the effects of PFMT between the Intervention Group (IG) and the Control Group (CG) and exploring the effects with and without PFMT, in pregnant women. Methods: Participated in this RCT, pregnant women (aged 21-44 years), having been applied two questionnaires: King's Health Questionnaire (KHQ's) and Broome Pelvic Muscle self-efficacy Scale. The amount of urine was assessed using the modified pad test (20 minutes) and the muscular strength of the Pelvic Floor Muscles (PFM) was measured with Oxford Grading Scale. There were two moments of assessment, T1: 1st time of evaluation (pre- delivery) and T2: 2nd time of evaluation (6 weeks after delivery). The IG was added an exercise plan with duration of six weeks, applicable in Preparation for childbirth classes and at home exercise plan for 9 weeks. Results:The loss of urine, quantified by the Pad test significantly reduced, 0.86±0.83at T1 to 0.50±0.67at T2 in IG (p= 0.021). The degree of muscle contraction, measured by the Oxford Grading Scale, increased significantly in IG (p<0.001) from 3.59±0.85 to 4.82 ± 0:39 and did not change significantly in the CG (p=0.609). The total KHQ and severity of symptoms were observed significant improvements in both groups (p <0.05). As for the scale of Broome - Total scale women's IG improved significantly (p = 0.001 and p = 0.031, respectively) while in CG women no significant change (p> 0.05). Conclusion: PFMT can prevent and treat SUI, and recommend strength training of the PFM during pregnancy, two times per week for at least 6-9 weeks, making it extremely relevant for clinical practice.
Enquadramento: A Incontinência Urinária de Esforço (SUI) é o tipo mais comum em mulheres grávidas, tendo implicações prejudiciais para a qualidade de vida. O treino dos músculos do pavimento pélvico (PFMT) é considerado um tratamento de primeira linha para a SUI. Uma vez existirem poucos estudos randomizados controlados (RCT) nesta população, é importante verificar a eficácia de mais um protocolo randomizado de PFMT. Objetivos: Este estudo teve como objetivos verificar os efeitos do treino dos músculos do pavimento pélvico entre o grupo de intervenção (IG) e o grupo controle (CG) e explorar os efeitos com e sem treino dos músculos do pavimento pélvico, em mulheres grávidas. Métodos: Participaram neste RCT, mulheres grávidas (com idades compreendidas entre os 21-44 anos), tendo sido aplicados dois questionários: King´s Health Questionnaire (KHQ’s) e Broome Pelvic Muscle Self-Efficacy Scale. A quantidade de urina foi avaliada através do pad-test modificado (20minutos) e a força muscular dos músculos do pavimento pélvico (PFM) foi medida com o Oxford Grading Scale. Houve dois momentos de avaliação, a 1ª avaliação (T1), no período pré-parto e a 2ª avaliação (T2), 6 semanas após o parto. Ao IG foi acrescentado um plano de exercícios com duração de 6 semanas, aplicável nas aulas de preparação para o parto, com supervisão e um plano de exercícios ao domicílio, durante 9 semanas, sem supervisão. Resultados: A perda de urina, quantificada pelo pad test, reduziu significativamente, de 0.86±0,83 em T1 para 0.50±0.67 em T2 no IG (p = 0.021). O grau de contração muscular, avaliado pelo Oxford Grading Scale, aumentou significativamente no IG (p <0.001) de 3.59±0,85 para 4.82±0.39 e não sofreu alterações significativas no GC (p=0.609). No KHQ total e severidade dos sintomas observaram-se melhorias significativas em ambos os grupos (p <0,05). Quanto à escala de Broome – Total, as mulheres do IG melhoraram significativamente (p=0.001 e p=0.031, respetivamente) e nas mulheres do CG não se verificaram nenhumas alterações significativas (p> 0,05). Conclusão: O PFMT pode prevenir e tratar a SUI, e recomenda-se o treino da força do PFM durante a gravidez, 2 vezes por semana durante pelo menos 6-9 semanas, tornando-se de extrema relevância para a prática clínica.
Franzén, Karin. "Interventions for urinary incontinence in women : survey and effects on population and patient level." Doctoral thesis, Örebro universitet, Hälsoakademin, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-12631.
Full textRahmanou, Philip. "Assessment of lower urinary tract function in women with urodynamic stress incontinence with and without detrusor overactivity." Thesis, Imperial College London, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589995.
Full textIrazabal, Flores Alessandra Milagros, and cante Giancarlo Yaya. "Association between physical activity and stress urinary incontinence in sportswomen from a private university in Lima - Peru." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/655774.
Full textIntroducción: La incontinencia urinaria en mujeres jóvenes deportistas es un trastorno frecuente y que interfiere con la práctica deportiva. Objetivo: Determinar si existe asociación entre la actividad física y la incontinencia urinaria por esfuerzo en mujeres deportistas de una universidad privada. Metodología: Estudio transversal analítico, desarrollado en las mujeres deportistas de la Universidad Peruana de Ciencias Aplicadas. Se utilizó el Cuestionario Internacional de Actividad Física – versión corta (IPAQ –SF) para determinar el nivel de actividad física y el Formulario abreviado del cuestionario de Cuestionario Internacional de Incontinencia de formato corto (ICIQ – SF) para determinar la incontinencia urinaria por esfuerzo. Resultados: De las 92 deportistas analizadas en el estudio, el 75% realizaba actividad física alta, el 47, 8% presentaron incontinencia urinaria, de las cuales el 63.3% pertenecían a incontinencia urinaria por esfuerzo. En el análisis bivariado entre la actividad física y la incontinencia urinaria por esfuerzo, el 46% de las deportistas que realizaba actividad física alta presentaban incontinencia urinaria por esfuerzo en comparación con el 10 % que realizaba actividad física moderada o baja, siendo significativo (p<0.05). En el análisis multivariado, se evidenció que las mujeres que realizan actividad física alta tienen 7.92 veces más prevalencia de Incontinencia Urinaria por Esfuerzo que las mujeres que realizan actividad física moderada o baja, siendo significativo (p=0.04) y ajustado a las variables edad, tipo de deporte y tiempo de deporte. Conclusión: Se encontró asociación entre la Actividad Física de alta intensidad con la Incontinencia Urinaria por Esfuerzo en deportistas mujeres universitarias.
Tesis
Spjuth, Sofia, and Sara Elomri. "The Nurse's Role in the Care of Females with Urinary-incontinence in South Africa : - An empirical study." Thesis, Hälsohögskolan, Högskolan i Jönköping, HHJ, Avd. för omvårdnad, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-42639.
Full textKhaida, Lina Sarah. "Prevalência e fatores de risco da incontinência urinária em atletas de diferentes modalidades desportivas: revisão bibliográfica." Bachelor's thesis, [s.n.], 2018. http://hdl.handle.net/10284/6723.
Full textIntrodução: a prática desportiva leva a muitos benefícios físicos e psicológicos, mas, paradoxalmente, a sua exigência poderá causar disfunções, nomeadamente génito-urinárias. Objetivo: avaliar a prevalência e os fatores de risco da incontinência urinária (IU) em atletas de diferentes modalidades desportivas. Metodologia: a pesquisa foi realizada nas bases de dados Scielo e PubMed, fundamentada em artigos compreendidos entre os anos de 2007 e 2017, avaliados segundo a escala Critical Appraisal Skills Programme (CASP). Resultados: nesta revisão foram incluídos 11 estudos, com um total de 3666 participantes do sexo feminino, atletas e sedentárias, com uma média de idades de 24,49±6,75 anos. As atletas, independentemente da modalidade ou do nível desportivo, são mais suscetíveis de desenvolver incontinência urinária do que as mulheres sedentárias. Conclusão: as atletas de distintas modalidades apresentam uma grande variabilidade quanto à prevalência da incontinência urinária. Nos desportos gravitacionais, os que incluem saltos, foi observada uma maior prevalência de IU. A competição, o impacto e o volume de atividade física realizada poderão ser fatores potenciadores ou fatores de risco para o aparecimento de IU.
Background: sports practice draws away many physical and psychological benefits but, paradoxically, its requirement can cause dysfunctions, notably genito-urinary. Objectives: assess the prevalence and the risk factors of urinary incontinence among athletes of different sports modality. Methodology: the survey was conducted in Scielo and PubMed databases, based on articles dated between 2007 and 2017, evaluated according to the Critical Appraisal Skills Program (CASP) scale. Results: 11 studies were included in this revision, with a total of 3666 participants, women athletes and sedentary women, with a medium age of 24,49±6,75 years old. Women athlete, regardless of the sport modality or sports level, are more likely to develop an urinary incontinence than sedentary women. Conclusion: athletes of different modalities present a large variability in the prevalence of urinary incontinence. In gravitational sports, which include jumps, a higher prevalence of UI has been noticed. Competition, impact and volume of physical activity can be potential factors or risk factors of appearance of UI.
N/A
Clark, Linnette. "Effect of transverse abdominus muscle activation on a pelvic muscle exercise program in women with stress urinary incontinence." Thesis, NSUWorks, 2008. https://nsuworks.nova.edu/hpd_pt_stuetd/12.
Full textNilsson, Margareta. "Female urinary incontinence : impact on sexual life and psychosocial wellbeing in patients and partners, and patient-reported outcome after surgery." Doctoral thesis, Umeå universitet, Obstetrik och gynekologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-55006.
Full textHenley, Janet. "Exploration of the process of changing district nursing practice to reflect research findings in the management of female urinary incontinence." Thesis, Queen Margaret University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.394549.
Full textPinho, Maria Teresa Silva Castanheira. "A intervenção fisioterapêutica e sua eficácia na incontinência urinária de stress: uma revisão bibliográfica." Bachelor's thesis, [s.n.], 2018. http://hdl.handle.net/10284/7022.
Full textIntrodução: A incontinência urinária (IU) afeta milhões de pessoas em todo em todo mundo, sendo que maioritariamente são mulheres de todas as idades. A incontinência urinária de stress (IUS) é a forma mais comum e afeta a qualidade de vida, a função sexual, a socialização e o estado emocional. A abordagem conservadora inclui Fisioterapia, considerada a primeira linha de tratamento. Objetivo: Identificar os vários procedimentos fisioterapêuticos no tratamento da incontinência urinária de stress e consequentemente analisar a eficácia destes procedimentos. Metodologia: Foi realizada uma pesquisa nas bases de dados/motores de busca: Pubmed, PEDro e Web of Science. Após a seleção dos estudos, segundo os critérios de inclusão e exclusão, foi avaliada a qualidade metodológica através da Critical Appraisal Skills Programme (CASP). Resultados: Foram selecionados 9 artigos, que englobam 1517 mulheres diagnosticadas com IUS. Apesar da diversidade de intervenções e protocolos utilizados, todas tiveram melhorias significativas no tratamento da IUS. Conclusão: A Fisioterapia parece ser eficaz no tratamento da IUS, uma vez que todas as intervenções estudadas apresentaram resultados positivos.
Background: Urinary incontinence (UI) affects millions of people worldwide, most of whom are women of all ages. Stress urinary incontinence (SUI) is the most common form and affects quality of life, sexual function, socialization and emotional state. Physical therapy is included in the conservative approach, which is considered the first line of treatment. Objectives: Identify several physiotherapeutic procedures in the treatment of stress urinary incontinence and analyze the effectiveness of these procedures. Methodology: A search was performed in the Pubmed, PEDro and Web of Science databases. After selecting the studies according to the inclusion and exclusion criteria, the methodological quality was evaluated through the Critical Appraisal Skills Program (CASP). Results: A total of 9 articles were selected, comprising 1517 women diagnosed with SUI. Despite the diversity of interventions and protocols used, all interventions had significant improvements in SUI treatment. Conclusion: Physical therapy seems to be effective in the treatment of SUI as all interventions have been successful.
N/A
Majid, Oneeb. "Population pharmacokinetic-pharmacodynamic modelling and optimal experimental design of Ro115-1240 in healthy subjects and stress urinary incontinence patients." Thesis, University of Manchester, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493915.
Full textJanse, van Rensburg Karina. "Pre-operative urodynamic studies : is there value in predicting post-operative stress urinary incontinence in women undergoing prolapse surgery." Thesis, Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/85662.
Full textENGLISH ABSTRACT: Aims of the study Urodynamic studies (UDS) have been suggested to be performed as part of the pre-operative work-up of patients undergoing prolapse surgery. Some women with POP have occult stress urinary incontinence (OSUI) and even if subjectively continent, have a higher incidence of developing de novo stress urinary incontinence (SUI). The aim of this study was to describe the outcome of a group of patients who had pre-operative UDS and manual prolapse reduction. Methods This was a retrospective descriptive study including all women who had prolapse surgery during the period January 2006 to December 2011. Patients received routine pre-operative UDS and manual reduction of prolapse, performed at maximum bladder capacity determined by UDS. Patients demonstrating urodynamic SUI or OSUI were offered a concomitant anti-incontinence procedure. Post-operative follow-up data included symptoms of SUI and clinical evidence of SUI. Results The final group consisted of 131 women. The mean age of the patients was 57 years (range 33 to 79) and parity 3.6 (range 0 to 7). The mean body mass index was 32 (range 19 to 53). Twenty-four (18.3%) women had demonstrable SUI on clinical examination at initial presentation in the clinic. At the time of urodynamic studies, forty patients (30.5%) had evidence of SUI determined by either UDS and/ or cough test in the standing position at maximum bladder capacity. Ninety-one women (69.5%) had no evidence of UI on UDS, of which 20(15.3%) demonstrated OSUI (SUI on manual reduction of prolapse at maximal bladder capacity determined by UDS). Of the 40 women with UI on UDS, 36 had 1-step surgery (combination of anti-incontinence procedure and prolapse repair) and 4 had prolapse surgery alone. Of the 20 women with OSUI on UDS, 16 had 1-step (combined) surgery and 4 prolapse surgeries only. Of the 4 who had prolapse surgery alone, 3 complained of post-operative SUI. In the group with no SUI on UDS and manual reduction of POP, 69 of the 71 women had follow-up data. Only 1 had demonstrable SUI on examination. The manual reduction test had a sensitivity of 42.9% and a specificity of 98.5% (95% CI, 92.0-99.9%). The positive predictive value was 75.0% (95% CI, 19.4-99.3%), with a high negative predictive value of 94.4% (95% CI, 86.2-98.8%). Conclusion The numbers in our study are too small to determine sensitivity and positive predictive value of UDS and manual prolapse reduction for the detection of OSUI. However, our data shows promise in identifying POP patients without OSUI, which is a complement of the hypothesis. We recommend that UDS can be performed pre-operatively in women undergoing prolapse surgery, to identify patients with urodynamic stress incontinence. Manual reduction of the prolapse at maximum bladder capacity can then be done to identify a subgroup of patients without OSUI. Future research is needed on the true predictive value of reduction stress testing with larger numbers.
AFRIKAANSE OPSOMMING: Doel van die studie Urodinamiese studies (UDS) word voorgestel as deel van die pre-operatiewe ondersoeke voor prolaps chirurgie gedoen word. Sommige vroue met genitale prolaps het verborge druklek, en selfs as hulle subjektief kontinent is, het hulle ‘n groter insidensie van de novo druklek. Die doel van die studie was om die uitkoms van ‘n groep pasiënte wat pre-operatiewe UDS en manuele prolaps reduksie gehad het, te beskryf. Metodes Die studie was ‘n retrospektiewe beskrywende studie. Al die pasiënte wat prolapse chirurgie in die tydperk Januarie 2006 tot Desember 2011 gehad het, is ingesluit. UDS en manuele prolaps reduksie tydens maksimale blaaskapasiteit, bepaal deur UDS, was deel van die roetine pre-operatiewe ondersoeke. In die gevalle waar urodinamiese druklek of verborge druklek demonstreer is, is die opsie van ‘n meegaande prosedure vir kontinensie tydens prolaps chirurgie aangebied. Post-operatiewe opvolg inligting het simptome van druklek en kliniese bewys van druklek ingesluit. Resultate Die finale groep was 131 vroue reikwydte. Die gemiddelde ouderdom van die pasiënte was 57 jaar (reikwydte 33 - 79) en pariteit 3.6 (reikwydte 0 - 7). Die gemiddelde liggaamsmassa indeks was 32 (reikwydte 19 - 53). Vier-en-twintig (18.3%) vroue het aantoonbare druklek gehad met kliniese ondersoek tydens die eerste kliniek afspraak. Tydens UDS het 40(30.5%) pasiënte druklek getoon tydens UDS en/ of hoestoets in die staande posisie teen maksimale blaaskapasiteit. Een-en-negentig (69.5%) het geen tekens van urinêre inkontinensie tydens UDS demonstreer nie, waarvan 20(15.3%) verborge druklek demonstreer het (druklek met reduksie van prolapse tydens maksimale blaaskapasiteit, bepaal deur UDS). Veertig pasiënte het urodinamiese druklek gehad, waarvan 36 een-stap chirurgie (‘n kombinasie van prolaps herstel en meegaande kontinensie prosedure) en 4 prolaps chirurgie alleenlik gehad het. Uit die 20 vroue met verborge druklek tydens UDS, het 16 een-stap (kombinasie) chirurgie en 4 prolaps chirurgie alleen gehad. Uit die 4 wat prolaps chirurgie alleen gehad het, het 3 post-operatiewe klagtes van druklek gehad. In die groep wat geen inkontinensie tydens UDS en manuele prolaps reduksie gehad het nie, het 69 van die 71 vroue opvolg data gehad. Druklek kon net by een pasiënt met ondersoek demonstreer word. Die manuele reduksie toets het ‘n sensitiwiteit van 42.9% en ‘n spesifisiteit van 98.5% (95% CI, 92.0-99.9%) gehad. Die positiewe voorspellingswaarde was 75.0% (95% CI, 19.4-99.3%), en die negatiewe voorspellingswaarde was 94.4% (95% CI, 86.2-98.8%). Gevolgtrekking Die getalle in ons studie was te min om te bepaal wat die sensitiwiteit en positiewe voorspellingswaarde van UDS and manuele prolaps reduksie is om verborge druklek te demonstreer. Die belowende data om pasiënte te identifiseer met genitale prolaps sonder verborge druklek (‘n kompliment van die hipotese). UDS kan pre-operatief gedoen word in pasiënte wat prolapse herstel chirurgie benodig, om pasiënte met urodinamiese druklek te identifiseer. Manuele reduksie van die prolaps tydens maksimum blaas kapasiteit kan dan volg, om ‘n subgroep van pasiente sonder verborge druklek, uit te ken. Verdere navorsing, met groter getalle word benodig om die werklike voorspellende waarde van die reduksie toets te ondersoek.
Laycock, Josephine. "Assessment and treatment of pelvic floor dysfunction : physiotherapy in the management of pelvic floor dysfunction in relation to female urinary incontinence." Thesis, University of Bradford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316501.
Full textThiel, Marcelo. "Analise quantitativa da fibrose e semiquantitativa da reação inflamatoria de quatro diferentes slings sinteticos." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/308661.
Full textTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas
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Resumo: OBJETIVOS: Analisar quantitativamente, com método estereológico, a densidade de fibras colágenas formadas após implante de quatro diferentes tipos de sling;verificar por análise histopatológica a reação inflamatória. MATERIAS E MÉTODOS: Realizou-se o estudo em 70 ratas da raça Wistar, divididas em 3 grupos (A,B,C): No grupo A (30 ratas) implantou-se uma faixa de silicone e outra de submucosa intestinal suína, de 8x 4 mm, no tecido subcutâneo da parede abdominal. No grupo B (30 ratas), implantou-se, da mesma maneira, uma faixa de copolímeros de poligalactina com ácido poliglicólico e outra de polipropileno monofilamentar, de 8x 4 mm. Sutura com fio de nylon 5/0, fixou as faixas e, no grupo C (10 ratas), denominado controle, realizou-se dissecção do subcutâneo e aplicação do mesmo fio, sem implante de material. A coloração de Picro-Sirius, empregada apenas no 90° dia de pós-operatório, permitiu análise das fibras colágenas e a de Hematoxilia-eosina, o estudo histopatológico da reação inflamatória. Nos dias 7, 30 e 90 de pós-operatório, sacrificaram-se 10 ratas de cada grupo. RESULTADOS: No 7° dia, todos os materiais induziram moderada reação inflamatória, sem diferença com o controle. No 30° dia, os copolímeros de poligalactina com ácido poliglicólico apresentaram a menor reação inflamatória, sem diferença com o controle. Neste período, polipropileno monofilamentar e silicone produziram inflamação moderada, enquanto que na submucosa intestinal suína, a intensidade foi severa. No 90° dia, a reação inflamatória, nos copolímeros de poligalactina com ácido poliglicólico, foi maior que antes, porém menor do que a do polipropileno monofilamentar e silicone, que permaneceram semelhantes entre si. Novamente, o grau de inflamação na submucosa intestinal suína continuou o maior de todos. Na análise estereológica, a densidade. de fibras colágenas dos copolímeros de poligalactina com ácido poliglicólico e polipropileno monofilamentar foi significativamente menor (61 % e 65% respectivamente) do que o silicone (85%) e submucosa intestinal suína (86%). CONCLUSÕES: Polipropileno monofilamentar foi o melhor material inabsorvível, pois induziu menos reação inflamatória que os outros materiais testados. Como a submucosa intestinal suína foi completamente removida, a intensa reação fibrótica que produz, toma-se útil, e responsável pelo suporte suburetral após a cirurgia
Abstract: OBJECTIVES: To analyse quantitatively, using stereological methods, the density of the collagen fibres induced by four types of sling materials, and verify by a histopathological analysis the corresponding inflammatory reaction, as fibrosis secondary to sling implantation is considered responsible for restoring urethral support and re-establishing continence in women with stress urinary incontinence, and new synthetic materials that promote adequate fibrosis with the least intensity and duration have been proposed to substitute the aponeurotic sling. MATERIALS AND METHODS: The study comprised 70 isogenic white Wistar rats divided into three groups: group A (30 rats) had 8 x 4 mm strips of silicone and porcine small intestine submucosa (SIS) implanted in the abdominal subcutaneous tissues; group B (30 rats) had 8 x 4 mm strips of polycaprolactone and polylactic acid copolymers and monofilament polypropylene (PLP) implanted the abdominal subcutaneous layer; while a control group of 10 rats had dissection and suturing with 5/0 Nylon in the abdominal subcutaneous layer, as used to fix the strips in the other rats. Picro-Sirius staining was used to assess collagen fibres, and haematoxylin-eosin for the histopathological study. At 7, 30 and 90 days after surgery, 10 rats from each group were killed and assessed. RESULTS: Afier 7 days all the materials induced a moderate inflammatory reaction that did not differ from that in the control group. At 30 days there was no difference between the control and polycaprolactone and polylactic acid copolymers, having the least inflammatory reaction. PLP and silicone produced a moderate inflammatory reaction, while the porcine SIS induced a more intense reaction. At 90 days there was a more intense inflammatory reaction in polycaprolactone and polylactic acid copolymers than before but it was less than with PLP and silicone, which again were no different. During this period the inflammatory reaction induced by SIS was greater. The stereological analysis indicated that collagen fibres induced by polycaprolactone and polylactic acid copolymers and PLP were less dense (61% and 65%, respectively), and significant1y less than with silicone (85%) and SIS (86%). CONCLUSION: PLP was the best nonabsorbable material as it induced a less intense inflammatory reaction than the other tested materials. As porcine SIS was completely absorbed the intense fibrosis induced is useful, as it is exclusively responsible for the urethral support later after surgery
Doutorado
Cirurgia
Mestre em Cirurgia
Moonat, Shweta. "Investigation of neural correlates of bladder control using functional magnetic resonance imaging (fMRI) in patients with overactive bladder (OAB)." Master's thesis, Temple University Libraries, 2008. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/217452.
Full textM.S.E.E.;
Overactive bladder (OAB) is considered to be a disorder of the urinary bladder and is defined by the International Continence Society Terminology Committee as "urgency, with or without urge incontinence, usually with frequency and nocturia". There is some preliminary evidence using functional magnetic resonance imaging (fMRI) that the brain response to bladder filling in OAB patients is abnormal. The purpose of this research is to determine whether there are Central Nervous System (CNS) differences in modulating bladder function that contribute to, or are themselves the cause of the symptoms in OAB patients. We further investigated the pharmacological fMRI changes
Temple University--Theses