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1

Zhu, Jianqiang, Xinglong Xie, Meizhi Sun, Qunyu Bi, and Jun Kang. "A Novel Femtosecond Laser System for Attosecond Pulse Generation." Advances in Optical Technologies 2012 (January 15, 2012): 1–6. http://dx.doi.org/10.1155/2012/908976.

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We report a novel ultrabroadband high-energy femtosecond laser to be built in our laboratory. A 7-femtosecond pulse is firstly stretched by an eight-pass offner stretcher with a chirp rate 15 ps/nm, and then energy-amplified by a two-stage optical parametric chirped pulse amplification (OPCPA). The first stage as preamplification with three pieces of BBO crystals provides the majority of the energy gain. At the second stage, a YCOB crystal with the aperture of ~50 mm is used instead of the KDP crystal as the gain medium to ensure the shortest pulse. After the completion, the laser will deliver about 8 J with pulse duration of about 10 femtoseconds, which should be beneficial to the attosecond pulse generation and other ultrafast experiments.
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2

Babin, A. A., A. M. Kiselev, Aleksandr M. Sergeev, and A. N. Stepanov. "Terawatt femtosecond Ti:sapphire laser system." Quantum Electronics 31, no. 7 (July 31, 2001): 623–26. http://dx.doi.org/10.1070/qe2001v031n07abeh002015.

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3

TORIZUKA, Kenjl, Mikio YAMASHITA, and Takuzo SATO. "Femtosecond-pulse dye laser system." Review of Laser Engineering 15, no. 11 (1987): 842–48. http://dx.doi.org/10.2184/lsj.15.842.

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4

Makari, Sarah, and Richard Potvin. "Cataract Surgery and the LenSx® Femtosecond Laser System—2015 Update." US Ophthalmic Review 8, no. 1 (2015): 10. http://dx.doi.org/10.17925/usor.2015.8.1.10.

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Femtosecond laser-assisted cataract surgery continues to gain popularity as clinicians adopt the technology with the desire to improve the safety and efficacy of cataract surgery. The technology continues to evolve as clinical experience points to improvements to better meet the needs of surgeons and patients. The effect of these system updates, and the increasing body of experience with femtosecond laser systems, has reduced complication rates and seen the technology applied to more challenging cases. This article provides an updated review of the LenSx® femtosecond Laser system, including recent system modifications and the most- recent published literature.
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5

Li, Dong Juan, Guang Hua Cheng, Zhi Yang, and Yi Shan Wang. "Ultrafast Laser Machine Based on All-Fiber Femtosecond Laser System." Advanced Materials Research 652-654 (January 2013): 2374–77. http://dx.doi.org/10.4028/www.scientific.net/amr.652-654.2374.

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A femtosecond laser machine consisting of femtosecond fiber laser, trepanning head, linear motor stages system and Siemens 840D system has been integrated for industry application. The femtosecond laser source is all fiber system which contains a fiber mode-lock laser at 1053 nm with a repetition rate of 3.9 MHz, a double-cladding gain fiber amplifiers and a PCF amplifier. An acoustical modulator has employed to tune repetition rate from 3.9 MHz to 100 KHz. An in-line fiber chirped grating is used to stretch the pulse duration to 700 ps. After the PCF amplifier pulse is compressed to sub-ps with 50% efficiency based two grating compressor. The system outputs an average power of 15 W at 100 KHz and 800 fs. Using four wedges trepanning head, cylinder hole is drilled in 1mm thickness SiC ceramics in 30 s.
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6

Lin, Ren, Zi Jing Zhong, Chun Yu Wang, and Xue Hao. "Femtosecond Laser Micro-Nanofabrication Technology and its Experimental System." Advanced Materials Research 760-762 (September 2013): 286–89. http://dx.doi.org/10.4028/www.scientific.net/amr.760-762.286.

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In this paper,a 3D femtosecond laser micro-nanofabrication system has been built. CAD model of 2D picture conversion data based on femtosecond laser micro-nanofabrication system have been also discussed. At last, the 2D hand model has been fabricated using the fabrication system we have built.
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7

Tikhomirov, S. A. "Femtosecond System with Pulse Pumping of Seed Laser and Amplifier by Using a Single Power Unit." Devices and Methods of Measurements 12, no. 1 (March 19, 2021): 23–29. http://dx.doi.org/10.21122/2220-9506-2021-12-1-23-29.

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For several decades development of methods for generating ultrashort pulses has been an independent urgent scientific and technical problem. There is a constant improvement both in the methods of such pulses receiving and in methods of their use. The aim of this work was to investigate the possibility of realizing the coordinated operation of two fundamentally different types of pump lasers for the femtosecond oscillator and amplifier based on one single-lamp laser head and to create on this basis a compact high-power femtosecond system with pulsed pumping and one power unit.The practical implementation of two types of pulsed lasers (nano- and picosecond ones operating, respectively, in Q-switch and modelock regime) on a single laser head with two active elements and one pump lamp is carried out. The required synchronization in time the pump pulse femtosecond amplifier formation and quasi-stationary region of generated pulses in the output radiation of a femtosecond Ti:sapphire is obtained.On this basis a compact, pulse pumped monoblock laser system has been developed that can generate femtosecond pulses with a duration of 50–150 fs with an energy up to 1 mJ and a high enough pulse repetition rate (up to 1 kHz which is determined by the type of laser head and pump unit used). In the developed laser system a compact scheme of a stretcher-compressor with a single common diffraction grating is used.Laser systems of this type characterized by a relatively low cost due to the use of a single power supply unit for simultaneous pumping of the amplifier and oscillator, as well as lower requirements for the quality of optical elements and usage conditions due to the pulse mode of operation, are quite practical and can be used both in scientific research in the field of ultra-high-speed kinetic spectroscopy and nonlinear optics, as well as in numerous technical applications, particular in the precision processing of materials, as optical simulators of the action of heavy charged particles in testing the radiation resistance of integrated circuits and electronic modules.
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8

Venkatakrishnan, Krishnan. "Femtosecond pulsed laser direct writing system." Optical Engineering 41, no. 6 (June 1, 2002): 1441. http://dx.doi.org/10.1117/1.1476324.

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9

Agranat, Mikhail B., Sergei I. Ashitkov, Anatoliy A. Ivanov, Aleksandr V. Konyashchenko, Andrei V. Ovchinnikov, and Vladimir E. Fortov. "Terawatt femtosecond Cr : forsterite laser system." Quantum Electronics 34, no. 6 (June 30, 2004): 506–8. http://dx.doi.org/10.1070/qe2004v034n06abeh002714.

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10

Murnane, M. M., and R. W. Falcone. "High-power femtosecond dye-laser system." Journal of the Optical Society of America B 5, no. 8 (August 1, 1988): 1573. http://dx.doi.org/10.1364/josab.5.001573.

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11

Gaković, B., S. Petrović, A. Krmpot, D. Pantelić, B. Jelenković, E. Stratakis, and C. Fotakis. "Low and high repetition frequency femtosecond lasers processing of tungsten-based thin film." Laser and Particle Beams 32, no. 4 (October 22, 2014): 613–19. http://dx.doi.org/10.1017/s0263034614000627.

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AbstractIn this work we reported low and high repetition frequency femtosecond laser-induced modifications of tungsten-based thin film. The tungsten-titanium (WTi) thin film, thickness of 190 nm, was deposited by sputtering on single crystal Si (100) wafer. Irradiations were performed in air by linearly polarized and focused femtosecond laser beams with following parameters: (1) pulse duration 160 fs, wavelength 800 nm, laser repetition frequency (LRF) 75 MHz — high LRF, and (2) duration 40 fs, wavelength 800 nm, LRF of 1 kHz — low LRF. The results of femtosecond lasers processing of the WTi thin film revealed laser induced periodical surface structures (LIPSS) in the case of low LRF regime. LIPSSs were formed with different periodicity and different orientation to the laser polarization at the surface: micro-scale LIPSSs with orientation perpendicular to the laser polarization and nano-scale LIPSSs parallel and perpendicular to the laser polarization. After processing of the WTi/Si system in high LRF regime ablation and nano-particles formation were registered.
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12

Peng, Yu Feng, Xiao Li Pan, De Wen Meng, and Fang Peng. "Characteristics of Femtosecond Laser Interaction with the Two-Level Atom System in Optical Materials." Advanced Materials Research 529 (June 2012): 164–68. http://dx.doi.org/10.4028/www.scientific.net/amr.529.164.

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With the development of laser technology, the femtosecond laser has been more and more extensively used both on scientific research and practical application. The interaction of femtosecond laser with two-level atoms in optical materials was discussed. The evolution of femtosecond pulse in resonant atomic medium with long distance, and the influence of the distribution of the laser field amplitude, which were Gaussian, hyperbolic secant, and asymmetric hyperbolic secant, on the two-level atomic transition probability is presented. Also the dynamic analysis of temporal evolution of atomic transition in a two-level system under the radiation of the frequency-chirped field in optical materials is analyzed.
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13

Cranfield, Charles, Ze'ev Bomzon, Daniel Day, Min Gu, and Sarah Cartmell. "Mechanical Strains Induced in Osteoblasts by Use of Point Femtosecond Laser Targeting." International Journal of Biomedical Imaging 2006 (2006): 1–6. http://dx.doi.org/10.1155/ijbi/2006/21304.

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A study demonstrating how ultrafast laser radiation stimulates osteoblasts is presented. The study employed a custom made optical system that allowed for simultaneous confocal cell imaging and targeted femtosecond pulse laser irradiation. When femtosecond laser light was focused onto a single cell, a rise in intracellularCa2+levels was observed followed by contraction of the targeted cell. This contraction caused deformation of neighbouring cells leading to a heterogeneous strain field throughout the monolayer. Quantification of the strain fields in the monolayer using digital image correlation revealed local strains much higher than threshold values typically reported to stimulate extracellular bone matrix production in vitro. This use of point targeting with femtosecond pulse lasers could provide a new method for stimulating cell activity in orthopaedic tissue engineering.
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14

Spence, Stephanie, Takaaki Harada, Athanasios Margiolakis, Skylar Deckoff-Jones, Aaron N. Shugar, James F. Hamm, Keshav M. Dani, and Anya R. Dani. "Applicability of Femtosecond Lasers in the Cross-section Sampling of Works of Art." MRS Advances 2, no. 33-34 (2017): 1801–4. http://dx.doi.org/10.1557/adv.2017.242.

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ABSTRACTIssues in traditional cross-section sampling of paintings and other cultural artifacts with a scalpel, such as crumbling, delamination and paint compression, can deter conservators from sampling fragile paint layers. Often, such sampling carries the risk of causing further damage from a scalpel, which outweighs the benefits of scientific investigation. Here, we show that femtosecond lasers offer a viable alternative to obtaining cross-sections with minimal damage to the surrounding artwork. A Regenerative Ti:Sapphire amplifier system with a pulse duration of 70 femtoseconds, a few milliwatts of average power and a repetition rate of 1 kHz (1000 pulses/sec) was used for the study. Tests were performed on oil paintings ranging in age from the 19th century to late 20th century. Effective settings were determined to be 2 mW of power at a speed of 10mm/sec using an 800nm laser. Preliminary results suggest femtosecond lasers could be a viable alternative for obtaining paint cross-sections when traditional sampling methods cause unnecessary damage to fragile materials.
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15

Potvin, Richard, and Sarah Makari. "Cataract Surgery and the LenSx® Femtosecond Laser System." US Ophthalmic Review 06, no. 02 (2013): 89. http://dx.doi.org/10.17925/usor.2013.06.02.89.

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The use of femtosecond laser systems in cataract surgery has been stated to be arguably the single biggest change to the procedure since phacoemulsification. The combination of a controllable high-frequency laser with increasingly advanced ocular imaging technology provides for a surgical precision that is difficult or impossible to duplicate manually. As a new technology, much clinical research is underway to identify best practices, and quantify the benefits of femtosecond cataract surgery. The main measures of interest are improvements in surgical precision, reduced complication rates and lower variability in clinical outcomes compared with manual procedures. The lower variability in outcomes would translate to a higher percentage of patients achieving their desired refractive target after surgery. This article provides an overview of the LenSx® femtosecond laser system, some of the ways in which it is being utilized in cataract surgery, and related surgical/ clinical results recently reported in the peer-reviewed literature.
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16

Gai, Xiao Chen, Zhi Wei Dong, Qing Liang Zhao, and Hong Bin Liu. "Femtosecond Laser Micromachining of SiC Ceramic Structures." Materials Science Forum 770 (October 2013): 21–24. http://dx.doi.org/10.4028/www.scientific.net/msf.770.21.

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Femtosecond laser micromachining technology shows abroad application background in the field of micro manufacturing due to its unique advantages, especially for micromachining of ultrahard materials such as Silicon carbide (SiC) ceramic. The femtosecond laser micromachining system was set up, by using the system, effects of scanning velocity and laser pulse energy on quality of micromachined features were evaluated. The optimized technological parameter was obtained as 8mW, 1mm/s with 1kHz repetition frequency respectively on the basis of the morphological characteristics and microstructure accuracy. Besides, V-shaped cavity of 300μm depth and 120°angle was generated with layer-by-layer scan machining. Thus femtosecond laser micromachining technology is an effective method for hard and brittle materials precision processing.
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17

LENZNER, M. "FEMTOSECOND LASER-INDUCED DAMAGE OF DIELECTRICS." International Journal of Modern Physics B 13, no. 13 (May 30, 1999): 1559–78. http://dx.doi.org/10.1142/s0217979299001570.

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Optical damage in non-metals (dielectrics) may severely affect the performance of high-power laser systems as well as the efficiency of optical systems based on nonlinear processes and has therefore been subject to extensive research for some 30 years. The current knowledge of laser-induced optical damage in these materials is reviewed. Emphasis is placed on the recent extension of available experimental data into the femtosecond range. Recent results are presented achieved with a sub-10 fs laser system which explores the limits of time resolution as well as the limit of intensities that a solid can sustain without irreversible damage. It is concluded that sub-10fs laser pulses open up the way to reversible nonperturbative nonlinear optics at intensities greater than 1014 W/cm 2 (slightly below damage threshold) and to nanometer-precision laser ablation (slightly above threshold) in dielectric materials.
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18

Khorkov, Kirill S., Valery G. Prokoshev, and Sergei M. Arakelian. "Laser-induced methods for obtaining carbon nanomaterials in liquid nitrogen under femtosecond radiation." Image Journal of Advanced Materials and Technologies 6, no. 2 (2021): 101–12. http://dx.doi.org/10.17277/jamt.2021.02.pp.101-112.

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The paper presents the experimental results of nanostructures formation under the influence of femtosecond laser radiation on carbon samples at liquid nitrogen temperatures. Two femtosecond laser systems were used to study the processes of laser action on highly oriented pyrolytic graphite and glassy carbon samples in liquid nitrogen: titanium-sapphire laser system with wavelength 800 nm, pulse duration 50 fs, energy 1 mJ, and repetition frequency of 1 kHz; ytterbium laser system with wavelength 1030 nm, pulse duration 280 fs, energy 150 µJ, and repetition frequency of 10 kHz. Cryostats, including those with the possibility of observing the laser action process, were collected for the experiments. As a result of laser action on the surface of the processed carbon samples, sheets of exfoliated graphene of various sizes and shapes (sheets, tapes, crumpled graphene), as well as nanostructures in the form of nanopeaks, were obtained. The mechanisms of graphene exfoliation under femtosecond laser action in liquid nitrogen, consisting in intercalation and further heating of nitrogen molecules in the interplanar space of graphite, were proposed. The possibilities of further research and development of technologies for graphene formation using laser radiation are presented.
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19

Ren, Lin, Yan Li Shi, Xue Hao, and Run Lan Tian. "Experimental System for the Micro-Nanofabrication of Three-Dimensional Structures by Femtosecond Laser Two-Photon Absorption." Advanced Materials Research 760-762 (September 2013): 746–49. http://dx.doi.org/10.4028/www.scientific.net/amr.760-762.746.

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Fundamentals of two-photon photopolymerization have been introduced and a 3D femtosecond laser micro-nanofabrication system has been built. In this paper, 3D CAD data model based on femtosecond laser micro-nanofabrication system have been also discussed. The 3D various sphere-rod photonic crystal structure mimicking real atom structures in electronic crystals have been fabricated.
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20

Mossavi, K., Th Hofmann, F. K. Tittel, and G. Szabó. "Ultrahigh‐brightness, femtosecond ArF excimer laser system." Applied Physics Letters 62, no. 11 (March 15, 1993): 1203–5. http://dx.doi.org/10.1063/1.108734.

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21

Steinmeyer, Joseph D., Cody L. Gilleland, Carlos Pardo-Martin, Matthew Angel, Christopher B. Rohde, Mark A. Scott, and Mehmet Fatih Yanik. "Construction of a femtosecond laser microsurgery system." Nature Protocols 5, no. 3 (February 11, 2010): 395–407. http://dx.doi.org/10.1038/nprot.2010.4.

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22

Pollock, T. M., M. P. Echlin, and A. Mottura. "Femtosecond Laser Tomography Using the TriBeam System." Microscopy and Microanalysis 19, S2 (August 2013): 698–99. http://dx.doi.org/10.1017/s1431927613005485.

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23

Togashi, T., Y. Nabekawa, T. Sekikawa, and S. Watanabe. "High-peak-power femtosecond Cr:forsterite laser system." Applied Physics B 68, no. 2 (February 1999): 169–75. http://dx.doi.org/10.1007/s003400050602.

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24

NGOI, K. A., D. X. HOU, S. T. HOH, L. H. K. KOH, and Y. Z. DENG. "IN VITRO EXPERIMENT STUDY ON ABLATION PARAMETERS IN FEMTOSECOND LASER-OCULAR TISSUE INTERACTION." International Journal of Nanoscience 04, no. 04 (August 2005): 483–88. http://dx.doi.org/10.1142/s0219581x05003292.

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In order to apply femtosecond laser technology in ophthalmology, especially in glaucoma treatment, femtosecond laser-ocular tissue interaction research was conducted. Focusing angle, output power, irradiance duration are three important laser parameters for ophthalmic microsurgery. In our work, the relationship of the three different laser parameter versus cutting effect was investigated respectively by an in-vitro experiment using an 800 nm-wavelength 150 fs-pulse-length laser system. This experiment aims to minimize the effects of thermal damage, while at the same time maximizing the speed or quality of the tissue ablation process. The experiment result shows that there is a great potential to optimize the surgical effects using femtosecond laser compared to that using a longer pulse laser.
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25

Astafiev, A. A., A. A. Gulin, A. A. Vasin, A. M. Shakhov, A. D. Zalessky, A. A. Osychenko, and V. A. Nadtochenko. "Mass spectrometry analysis of C-dots produced by femtosecond laser irradiation of L-lysine film." Journal of Physics: Conference Series 2086, no. 1 (December 1, 2021): 012157. http://dx.doi.org/10.1088/1742-6596/2086/1/012157.

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Abstract The production of carbon dots (C-dots) by femtosecond lasers within living cells and tissues is a novel approach, which has a great potency for intracellular bioimaging. An exact mechanism of fluorescent particles production as well as their composition still remains unknown. In this work we use L-lysine film as a model system to study the mechanism and the composition of C-dots produced by femtosecond laser irradiation investigated by time-of-flight secondary ion mass spectrometry (ToF-SIMS).
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26

TOKIZAKI, Takashi, Norio MORITA, Yuzo ISHIDA, and Tatsuo YAJIMA. "CW mode-locked YAG-laser-pumped femtosecond dye laser system." Review of Laser Engineering 16, no. 9 (1988): 600–605. http://dx.doi.org/10.2184/lsj.16.600.

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27

Gheorghe, M., F. P. G. Stochioiu, D. Manolache, M. R. Dijmărescu, and D. Iliescu. "Analysis and development on general structure and characteristics of laser interferometry systems." IOP Conference Series: Materials Science and Engineering 1268, no. 1 (November 1, 2022): 012010. http://dx.doi.org/10.1088/1757-899x/1268/1/012010.

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The laser interferometry systems have been developed for scientific studies, industrial operations, artworks investigation, etc. They present common generic elements, such as laser, optics, beam, polarization, splitting, interferometry, etc., but also diverse specific components and features,such as He-Ne or femtosecond laser, quantum cascade lasers, non-polarising beam splitter, collimating lens, high reflecting mirror, photodetector, attosecond pulse train, etc., as the case. The paper presents, also, a development on general structure and characteristics of laser interferometry systems. Analytical descriptors are introduced for the main implied entities, as well as some qualitative features referring to measurement object, coordinate system, lasers, laser beams, optics, output beams, detectors, environmental sensors and compensation modules, electronics, process software and computer, assembly, calibration, etc. The conclusions accord attention to further laser interferometry development regarding the interacting processes, analytical modelling, simulation, operational characteristics, etc.
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Qi, Li Tao, and Jin Ping Hu. "Femtosecond Laser Micromachining of High Quality Groove on Sapphire Surface." Applied Mechanics and Materials 217-219 (November 2012): 2213–16. http://dx.doi.org/10.4028/www.scientific.net/amm.217-219.2213.

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In this paper, high quality grooves were fabricated by femtosecond laser pulse on sapphire surface. Grooves were fabricated under different experimental conditions. The lateral and vertical machining precision was evaluated by scanning electron microscopy and profilometer. High quality grooves could be obtained at the condition of low pulse energy, high scanning-speed and increasing the number of laser scans. The relationship between the width and depth of the groove and the key parameters of femtosecond laser micromachining system was studied. Several samples of the high quality grooves were obtained by femtosecond laser pulses. High quality grooves have a potential application of the fabrication of sapphire-based devices.
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29

Xiang, Ran, Xin Yu Tan, and Hui Li Wei. "Influence of Electron-Phonon Coupling Coefficient on Properties in Femtosecond Laser Ablation." Materials Science Forum 814 (March 2015): 144–49. http://dx.doi.org/10.4028/www.scientific.net/msf.814.144.

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Thermodynamics effects generated by femtosecond laser ablation are very important. In this work, the numerical simulation of high-energy femtosecond laser ablation especially the electro-phonon coupling coefficient influence of high-energy femtosecond laser ablation on metal target was studied. A new two-temperature model (TTM) which considered the effects of electron density of states (DOS) on electron-phonon coupling coefficient was first established, then the temperature evolvement for electron and lattice in different electro-phonon coupling coefficient G, and the effect of G on electron temperature and lattice temperature and electron-phonon coupling time were emphatically analyzed. The results showed that the electron-phonon coupling coefficient strongly affected the surface electron temperature and coupling time in the femtosecond laser ablation. The smaller the electron-phonon coupling coefficient was, the more the energy transmission from electronic to ion subsystem. As a result, the smaller the value of electron-phonon coupling coefficient, a more rapid decline for the temperature of electronic sub-system achieved. This work will offer help for the future investigation of material fabrication by femtosecond laser ablation.
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30

Xu, Yi, Jianzhou Wang, Yansui Huang, Yanyan Li, Xiaomin Lu, and Yuxin Leng. "Nonlinear temporal pulse cleaning techniques and application." High Power Laser Science and Engineering 1, no. 2 (June 20, 2013): 98–101. http://dx.doi.org/10.1017/hpl.2013.9.

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AbstractTwo different pulse cleaning techniques for ultra-high contrast laser systems are comparably analysed in this work. The first pulse cleaning technique is based on noncollinear femtosecond optical-parametric amplification (NOPA) and second-harmonic generation (SHG) processes. The other is based on cross-polarized wave (XPW) generation. With a double chirped pulse amplifier (double-CPA) scheme, although temporal contrast enhancement in a high-intensity femtosecond Ti:sapphire chirped pulse amplification (CPA) laser system can be achieved based on both of the techniques, the two different pulse cleaning techniques still have their own advantages and are suitable for different contrast enhancement requirements of different laser systems.
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31

El-Gendy, Ahmed O., Yousif Obaid, Esraa Ahmed, Chukuka S. Enwemeka, Mansour Hassan, and Tarek Mohamed. "The Antimicrobial Effect of Gold Quantum Dots and Femtosecond Laser Irradiation on the Growth Kinetics of Common Infectious Eye Pathogens: An In Vitro Study." Nanomaterials 12, no. 21 (October 26, 2022): 3757. http://dx.doi.org/10.3390/nano12213757.

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We studied the antimicrobial effect of gold quantum dots (AuQDs), femtosecond laser irradiation, and the combined effect of laser irradiation and AuQD treatment against common infectious eye pathogens. The INSPIRE HF100 laser system (Spectra Physics) provided a femtosecond laser, which was pumped by a mode-locked femtosecond Ti: sapphire laser MAI TAI HP (Spectra Physics), while a Quanta-Ray nanosecond Nd: YAG laser (Spectra-Physics) was used to precisely synthesize 7.8, 8.7, and 11.6 nm spherical AuQDs. Then, the in vitro growth kinetics and growth rate analysis of E. coli, methicillin-resistant Staphylococcus aureus, Enterococcus faecalis, Listeria monocytogenes, and Candida albicans (treated with the AuQDs, femtosecond laser irradiation, or combined laser and AuQDs treatment) was measured. The biocompatibility of the AuQDs with the retinal epithelial cell lines (ARPE-19) and their toxicity to the cells was assayed. The results showed that (1) in vitro irradiation using a 159 J/cm2 energy density obtained from the 400 nm femtosecond laser suppressed the growth of each of the five pathogens. (2) Similarly, treatment with the AuQDs was antimicrobial against the four bacteria. The AuQDs with an average size of 7.8 nm were more highly antimicrobial and biocompatible and were less cytotoxic than the larger AuQD sizes. (3) The combined femtosecond laser irradiation and AuQD treatment was more highly antimicrobial than each treatment alone. (4) The AuQD treatment did not impair the rate of wound closure in vitro. These findings suggest that combined femtosecond laser irradiation and AuQD treatment is significantly antimicrobial against Candida albicans, Gram-positive L. monocytogenes, S. aureus, and E. faecalis, as well as Gram-negative E. coli. The nontoxicity and biocompatibility of the AuQD particles tested suggest that this form of treatment may be clinically viable.
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32

Takita, Akihiro. "Femtosecond Laser Processing System with Target Tracking Feature." Journal of Laser Micro/Nanoengineering 1, no. 3 (December 2006): 288–91. http://dx.doi.org/10.2961/jlmn.2006.03.0026.

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33

Zeng, Shaoqun, Kun Bi, Songchao Xue, Yujing Liu, Xiaohua Lv, and Qingming Luo. "Acousto-optic modulator system for femtosecond laser pulses." Review of Scientific Instruments 78, no. 1 (January 2007): 015103. http://dx.doi.org/10.1063/1.2409868.

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34

Zhou Fengquan, 周锋全, 袁帅 Yuan Shuai, 郭政儒 Guo Zhengru, 郝强 Hao Qiang, 徐晖 Xu Hui, and 曾和平 Zeng Heping. "High Power Compact Fiber Femtosecond Laser Amplification System." Laser & Optoelectronics Progress 55, no. 10 (2018): 103201. http://dx.doi.org/10.3788/lop55.103201.

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35

Fukuta, Yusuke, Terutake Hayashi, Masaki Michihata, and Yasuhiro Takaya. "Development of a Novel Surface Processing System Using Femtosecond Pulse Train." Key Engineering Materials 523-524 (November 2012): 220–25. http://dx.doi.org/10.4028/www.scientific.net/kem.523-524.220.

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When a laser pulse interacts with metal or semiconductor target, the coherent phonon, which is the coherent motions of lattice and molecule vibrations in solids, is excited by the interaction of electrons and high latitude electric field. It has unique properties of decaying in approximately several picoseconds and substance specific frequency. Owing to that, femtosecond laser processing is the local processing with little heat diffusion and little thermal damage to the target, due to the ultrafast time scales. We propose a novel femtosecond pulse ablation process with oscillation of the coherent phonon by femtosecond pulse train. The pulse train is shaped using Spatial Light Modulator (SLM), which shift the phase of the passing light. And coherent phonon oscillations are enhanced and decayed due to the controlling the shape of pulse train. It is able to activate the lattice motion for processing efficiently, and hence the target is expected to be ablated with high accuracy and less thermal damage.
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36

Sun, Shu Feng. "Fabrication Technology of Involute Micro Gear Based on Two-Photon of Femtosecond Laser." Applied Mechanics and Materials 44-47 (December 2010): 670–74. http://dx.doi.org/10.4028/www.scientific.net/amm.44-47.670.

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Microfabrication is a kind of critical technology for the development of Micro Electro-Mechanical Systems (MEMS). The frequently-used microfabrication technologies are electric discharge machining, photoetching, LIGA and laser fabrication, et al. Micro structures may be fabricated by these technologies. The polymerization principle of two-photon of femtosecond laser is different from that of single-photon. Photoinitiator of photosensing material absorbs two photons simultaneously to accomplish energy level transition and to induce the material to occur photochemical reaction. For the material absorbing two photons, the energy of each photon is equivalent to half of the energy that needed by the material transiting from ground state to excited state. It is also equal to half of the energy needed by the material occurring single-photon absorption. Therefore, the photonic frequency of two-photon excitation light source is half of the single-photon light source. According to two-photon fabrication principle, machining system of two-photon of femtosecond laser is set up. Which includes light path transmission equipment, three dimensional micro displacement scanning stage and control software, et al. Involute micro gear is fabricated by two-photon of femtosecond laser generated by the system.
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37

Gasanova, K. S., E. N. Panteleev, and E. A. Shikhalieva. "A variant of using laser femtosecond facofragmentation without laser capsulotomy in the case of complicated cataract." Clinical cases in ophthalmology, no. 1 (May 10, 2023): 15–20. http://dx.doi.org/10.25276/2949-4494-2023-1-15-20.

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Purpose. To evaluate the effectiveness of using femtosecond phacofragmentation without laser capsulotomy in cataract phacoemulsification with a relatively narrow pupil against the background of pseudoexfoliation syndrome in combination with grade I lens subluxation. Material and methods. The subject of the study was a case of complicated cataract in patient Ya., 74 years old, with complaints of decreased vision in the right eye. Standard preoperative and postoperative examinations were performed. The patient underwent surgery using a phacoemulsifier (CenturionVisionSystem, Alcon, USA) with preliminary laser femtosecond support (Catalys TM Precision Laser System-Johnson&Johnson Vision). A three-part IOL AcrySof MA60AC (Alcon, USA) with an optical power of 22.0 diopters was implanted. The peculiarity of the operation was that at the stage of laser femtosecond support, only phacofragmentation was performed without capsulotomy. Result. In this case, only phacofragmentation was performed without the formation of capsulorhexis with laser femtosecond support of phacoemulsification against the background of a rigid, relatively narrow pupil, which made it possible to safely use the usual methods of mechanical pupil dilation followed by manual performance of capsulorhexis of the optimal diameter. On the 2nd day after the operation, visual acuity without correction was 0.5, with a correction of –0.75 diopters – 0.7. The result of surgical treatment in this case indicates that a separate use of femtosecond laser fragmentation of the lens without anterior capsulotomy is possible. In this case, it was applied taking into account the combined pathology: pseudoexfoliation syndrome, lens subluxation, relatively narrow pupil and the objective need to use the Malyugin ring, the planned method of fixing the IOL. The preserved anterior capsule made it possible to perform standard implantation of the Malyugin ring without any special features, followed by capsulorhexis of the optimal diameter. Conclusion. This example demonstrates the possibility of safely and effectively performing phacofragmentation without capsulorhexis at the stage of laser femtosecond support during cataract phacoemulsification, when the pupil diameter does not allow programming the optimal capsulorhexis size. Key words: ciliocapsular fixation, intraocular lens, pseudoexfoliation syndrome, femtosecond laser
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38

Dongyu Yan, Dongyu Yan, Bowen Liu Bowen Liu, Yuxi Chu Yuxi Chu, Huanyu Song Huanyu Song, Lu Chai Lu Chai, Minglie Hu Minglie Hu, and Chingyue Wang Chingyue Wang. "Hybrid femtosecond laser system based on a Yb:KGW regenerative amplifier for NP polarization." Chinese Optics Letters 17, no. 4 (2019): 041404. http://dx.doi.org/10.3788/col201917.041404.

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39

Zhang, Tianyong, Baoshan Guo, Lan Jiang, Tong Zhu, Yanhong Hua, Ningwei Zhan, and Huan Yao. "Single-Shot Multi-Frame Imaging of Femtosecond Laser-Induced Plasma Propagation." Materials 16, no. 8 (April 21, 2023): 3264. http://dx.doi.org/10.3390/ma16083264.

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Single-shot ultrafast multi-frame imaging technology plays a crucial role in the observation of laser-induced plasma. However, there are many challenges in the application of laser processing, such as technology fusion and imaging stability. To provide a stable and reliable observation method, we propose an ultrafast single-shot multi-frame imaging technology based on wavelength polarization multiplexing. Through the frequency doubling and birefringence effects of the BBO and the quartz crystal, the 800 nm femtosecond laser pulse was frequency doubled to 400 nm, and a sequence of probe sub-pulses with dual-wavelength and different polarization was generated. The coaxial propagation and framing imaging of multi-frequency pulses provided stable imaging quality and clarity, as well as high temporal/spatial resolution (200 fs and 228 lp/mm). In the experiments involving femtosecond laser-induced plasma propagation, the probe sub-pulses measured their time intervals by capturing the same results. Specifically, the measured time intervals were 200 fs between the same color pulses and 1 ps between the adjacent different. Finally, based on the obtained system time resolution, we observed and revealed the evolution mechanism of femtosecond laser-induced air plasma filaments, the multifilament propagation of femtosecond laser in fused silica, and the influence mechanism of air ionization on laser-induced shock waves.
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40

Kanellopoulos, Anastasios John. "Innovations in Femtosecond Laser Technology – The Use of the WaveLight® FS200 Laser for Flap Cutting during LASIK Surgery." European Ophthalmic Review 04, no. 01 (2010): 40. http://dx.doi.org/10.17925/eor.2010.04.01.40.

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Laser-assistedin situkeratomileusis (LASIK) involves the creation of a corneal flap and remodelling of the corneal stroma. This conventionally used a mechanical microkeratome but these devices are associated with variations in the flaps produced. The development of femtosecond excimer laser technology over the past 10 years has markedly improved the safety and efficiency of flap cutting during LASIK and provides superior performance. The Wavelight® FS200 laser is a recent development in femtosecond laser systems. This instrument is calibrated when switched on and prior to application of the applanation cone to the cornea surface, ensuring consistency in flap cutting. The Wavelight FS200 laser has a rapid firing speed that reduces the energy requirement, makes flap lifting easier, reduces procedure time and improves patient comfort. The system also provides consistency of flap diameter and thickness and allows for individualisation of flap morphology based on the patient’s condition. This article discusses clinical experience with the Wavelight FS200 laser for flap cutting in LASIK surgery.
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41

Kaur, Sarbjeet, Nick Van Steerteghem, Paramjit Kaur, Koen Clays, and Kamaljit Singh. "Synthesis, characterization and second-order nonlinear optical behaviour of ferrocene–diketopyrrolopyrrole dyads: the effect of alkene vs. alkyne linkers." Journal of Materials Chemistry C 4, no. 41 (2016): 9717–26. http://dx.doi.org/10.1039/c6tc03350d.

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New, thermally stable dipolar ferrocene–diketopyrrolopyrrole (Fc–DPP) dyads with alkene as a linker exhibited structure dependent first hyperpolarizabilities,βHRS, recorded by a femtosecond HRS technique using a femtosecond (120 fs) pulsed laser light system at 900 nm at ambient temperature.
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42

Chang, Chin Lung, Weij Hong Ju, Ching Liang Liou, Jik Chang Leong, and Lung Ming Fu. "Rapid Microfluidc Biochips Fabrication by Femtosecond Laser on Glass Substrate." Key Engineering Materials 483 (June 2011): 359–63. http://dx.doi.org/10.4028/www.scientific.net/kem.483.359.

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This paper uses a femtosecond laser scriber to perform the direct-writing ablation of glass substrate for the development of microfluidic biochips. The surface quality of the ablated microchannels was examined by scanning electron microscopy (SEM) and atomic force microscopy (AFM) measurement techniques. The developed femtosecond laser ablation system provides a versatile and economic approach for the fabrication of glass-base microfluidic chips. In the laser writing process, the desired microfluidic patterns are designed using commercial computer software and are then transferred to the laser scriber to ablate the trenches. The results show that a very smooth channel wall can be achieved through the annealing process at the temperature 650°C and 5 hours. The system provides an economic and powerful means of rapid glass microfluidic biochips development.
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43

Pajic, Bojan, Brigitte Pajic-Eggspuehler, Zeljka Cvejic, Christian Rathjen, and Viktor Ruff. "First Clinical Results of a New Generation of Ablative Solid-State Lasers." Journal of Clinical Medicine 12, no. 2 (January 16, 2023): 731. http://dx.doi.org/10.3390/jcm12020731.

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In the early 2000s, solid-state lasers emerged as an alternative technology to excimer systems in refractive surgery. Despite some technological limits at the time, good clinical results could be achieved with solid-state laser systems. This prospective case series reports clinical outcomes of five eyes treated with a newly developed solid-state laser system (AquariuZ) in three patients. Patients underwent preoperative examination, including corneal topo-and tomography, aberrometry, and confocal microscopy. All patients received a femtosecond LASIK with the Ziemer LDV Z8, a refractive treatment with the AquariuZ solid-state ablation laser, and were then followed up for a period of up to 12 months. The applied aspheric optimized profiles did not induce higher-order aberrations nor spherical aberration in any of these operated subjects. No eye lost BCVA lines throughout the duration of the follow-up. Six months after surgery, the safety index of patient 1 was 5, and for patients 2 and 3, it equaled 1. Confocal laser microscopy imaging findings were comparable to those seen typically for excimer lasers. The obtained results are encouraging and confirm that the new solid-state laser system is safe.
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44

Motoyama, Hiroto, Atsushi Iwasaki, Hidekazu Mimura, and Kaoru Yamanouchi. "Submicron structures created on Ni thin film by submicron focusing of femtosecond EUV light pulses." Applied Physics Express 16, no. 1 (January 1, 2023): 016503. http://dx.doi.org/10.35848/1882-0786/acaebe.

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Abstract Using a newly developed submicron focusing system equipped with a large-aperture Wolter mirror with a precisely figured surface, we irradiate a Ni thin film coated on a silicon substrate with femtosecond extreme ultraviolet (EUV) laser pulses, generated as high-order harmonics of near-infrared femtosecond laser pulses. At the fluence of up to 100 mJ cm−2 at the sample surface, we show that the surface morphology can be modified with a submicron spatial resolution and that a protruding structure is formed when the fluence is 60–70 mJ cm−2, exhibiting a characteristic feature of the femtosecond EUV light processing of a thin metal surface.
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45

Li, Wei, Xiao Wang, Yanlei Zuo, Yilin Hong, Bilong Hu, Zhaohui Wu, Jie Mu, Kainan Zhou, and Xiaoming Zeng. "A cylindrical Öffner stretcher based on ternary reflector for femtosecond petawatt-level laser system." Chinese Optics Letters 21, no. 7 (2023): 073201. http://dx.doi.org/10.3788/col202321.073201.

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46

Day, Daniel, Charles G. Cranfield, and Min Gu. "High-Speed Fluorescence Imaging and Intensity Profiling of Femtosecond-Induced Calcium Transients." International Journal of Biomedical Imaging 2006 (2006): 1–6. http://dx.doi.org/10.1155/ijbi/2006/93438.

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We have demonstrated a combined imaging system, where the physiology of biological specimens can be imaged and profiled at 10–20 frames per second whilst undergoing femtosecond laser irradiation. Individual GH3 cells labeled with the calcium fluorophore Fluo-3 were stimulated using a counter-propagating focused femtosecond beam with respect to the imaging system. As a result of the stimulation, calcium waves can be generated in COS cells, and laser-induced calcium oscillations are initiated in the GH3 cells. Single-photon fluorescence images and intensity profiles of the targeted specimens are sampled in real-time using a modified PerkinElmer UltraView LCI microscope.
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47

Liu Huagang, 刘华刚, 胡明列 Hu Minglie, 刘博文 Liu Bowen, 宋有建 Song Youjian, 柴路 Chai Lu, and 王清月 Wang Qingyue. "Power Ultraviolet Laser Source Based on Photonic Crystal Fiber Femtosecond Laser System." Chinese Journal of Lasers 36, no. 11 (2009): 2812–16. http://dx.doi.org/10.3788/cjl20093611.2812.

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48

Liao, Q., M. J. Wu, Z. Gong, Y. X. Geng, X. H. Xu, D. Y. Li, Y. R. Shou, et al. "Enhanced laser proton acceleration by target ablation on a femtosecond laser system." Physics of Plasmas 25, no. 6 (June 2018): 063109. http://dx.doi.org/10.1063/1.5025239.

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49

Zhao Qikai, 赵其锴, 丛振华 Cong Zhenhua, 刘兆军 Liu Zhaojun, 张行愚 Zhang Xingyu, and 赵智刚 Zhao Zhigang. "Hundred Microjoule Femtosecond Fiber Chirped Pulse Amplification Laser System." Chinese Journal of Lasers 48, no. 7 (2021): 0701001. http://dx.doi.org/10.3788/cjl202148.0701001.

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50

Li Feng, 李峰, 杨直 Yang Zhi, 赵卫 Zhao Wei, 李强龙 Li Qianglong, 胡晓鸿 Hu Xiaohong, 杨小君 Yang Xiaojun, and 王屹山 Wang Yishan. "Hundred Micro-Joules Level Femtosecond Fiber Laser Amplification System." Chinese Journal of Lasers 42, no. 12 (2015): 1202005. http://dx.doi.org/10.3788/cjl201542.1202005.

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