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1

MARRS, RICHARD P. "HUMAN IN-VITRO FERTILIZATION." Clinical Obstetrics and Gynecology 29, no. 1 (March 1986): 117. http://dx.doi.org/10.1097/00003081-198603000-00016.

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2

&NA;. "Human In-Vitro Fertilization." Clinical Obstetrics and Gynecology 29, no. 1 (March 1986): 205–6. http://dx.doi.org/10.1097/00003081-198603000-00025.

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3

Plachot, M., and N. Crozet. "Fertilization abnormalities in human in-vitro fertilization." Human Reproduction 7, suppl 1 (June 1, 1992): 89–94. http://dx.doi.org/10.1093/humrep/7.suppl_1.89.

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4

Mills, J. "Book Review: Human in Vitro Fertilization." Scottish Medical Journal 40, no. 3 (June 1995): 95. http://dx.doi.org/10.1177/003693309504000311.

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5

Zegers-Hochschild, Fernando, Bernard M. Dickens, and Sandra Dughman-Manzur. "Human rights to in vitro fertilization." International Journal of Gynecology & Obstetrics 123, no. 1 (August 6, 2013): 86–89. http://dx.doi.org/10.1016/j.ijgo.2013.07.001.

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6

Kolb, Bradford Alan, and Richard J. Paulson. "Unstimulated in vitro fertilization revisited." Reproductive Medicine Review 5, no. 2 (July 1996): 129–38. http://dx.doi.org/10.1017/s0962279900001289.

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The first attempts at in vitro fertilization (IVF) of human oocytes were performed during cycles utilizing human menopausal gonadotropin (hMG) and human chorionic gonadotropin (hCG). These early cycles resulted in a successful conception, which unfortunately ended as a tubal gestation. The birth of Louise Brown in 1978, the first successful IVF birth, was actually achieved following fertilization during a spontaneous cycle in which ovulation was triggered with endogenous luteinizing hormone (LH).However, due to the greater margin for error afforded by larger numbers of follicles, the practice of IVF rapidly evolved towards the use of controlled ovarian hyperstimulation (COH) to achieve higher pregnancy rates. It is easy to understand why this approach evolved. Oocyte harvesting was accomplished primarily by laparoscopy. Since oocyte yield per follicle was less than 100% and fertilization rates were limited, the relatively traumatic follicle aspiration process was more likely to result in embryo transfer if a greater number of follicles was present.
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7

Gardner, David K., Laura Reed, Donald Linck, Courtney Sheehan, and Michelle Lane. "Quality Control in Human In Vitro Fertilization." Seminars in Reproductive Medicine 23, no. 04 (2005): 319–24. http://dx.doi.org/10.1055/s-2005-923389.

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8

Sakkas, Denny, David Gardner, and Basak Balaban. "Laboratory Procedures for Human In Vitro Fertilization." Seminars in Reproductive Medicine 32, no. 04 (June 11, 2014): 272–82. http://dx.doi.org/10.1055/s-0034-1375179.

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9

Winston, R., and A. Handyside. "New challenges in human in vitro fertilization." Science 260, no. 5110 (May 14, 1993): 932–36. http://dx.doi.org/10.1126/science.8493531.

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10

Clarke, Gary N., Ross V. Hyne, Yvonne du Plessis, and W. Ian H. Johnston. "Sperm antibodies and human in vitro fertilization." Fertility and Sterility 49, no. 6 (June 1988): 1018–25. http://dx.doi.org/10.1016/s0015-0282(16)59954-3.

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11

Edwards, R. G., M. SEPPäLä, W. I. H. Johnston, H. W. JonesJr, L. Rauramo, K. Semm, O. Widholm, and N. Wiqvist. "Helsinki Statement on Human in Vitro Fertilization." Annals of the New York Academy of Sciences 442, no. 1 In Vitro Fert (May 1985): 571–72. http://dx.doi.org/10.1111/j.1749-6632.1985.tb37567.x.

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12

Angell, Roslyn R., A. A. Templeton, and R. J. Aitken. "Chromosome studies in human in vitro fertilization." Human Genetics 72, no. 4 (April 1986): 333–39. http://dx.doi.org/10.1007/bf00290960.

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13

Yee, Bill. "Ultrasonography in human in vitro fertilization programs." Theriogenology 29, no. 1 (January 1988): 85–94. http://dx.doi.org/10.1016/0093-691x(88)90033-7.

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14

Feng, H., and A. Hershlag. "Fertilization abnormalities following human in vitro fertilization and intracytoplasmic sperm injection." Microscopy Research and Technique 61, no. 4 (June 10, 2003): 358–61. http://dx.doi.org/10.1002/jemt.10349.

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15

Elm, Laura. "Embryo Mortality and In Vitro Fertilization." Ethics & Medics 43, no. 4 (2018): 3–4. http://dx.doi.org/10.5840/em20184347.

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This essay hopes to convey the problematic framework of outcomes for assisted reproductive technologies (ARTs) as they are published today, reframe the logic to focus on human embryo mortality, and quantify a population of human beings generally not accounted for in publicly available in-vitro fertilization data. This analysis, conducted using the CDC’s 2015 National Summary data in conjunction with a retrospective study conducted by one of the nation’s largest ART delivery systems, is one of the first attempts to estimate pre-transfer embryo mortality in IVF. This analysis focuses on fresh non-donor cycles only, that is, rounds of IVF treatment that include immediate transfer of at least one embryo and in which the embryos transferred were engendered using the recipient’s own eggs.
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16

Marrs, Richard P. "Laboratory Conditions for Human In-Vitro Fertilization Procedures." Clinical Obstetrics and Gynecology 29, no. 1 (March 1986): 180–89. http://dx.doi.org/10.1097/00003081-198603000-00023.

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17

Edwards, Robert G. "The bumpy road to human in vitro fertilization." Nature Medicine 7, no. 10 (October 2001): 1091–94. http://dx.doi.org/10.1038/nm1001-1091.

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18

Zenzes, Maria Teresa, Lutz Belkien, Joachim Bordt, Irena Kan, Hermann P. G. Schneider, and Eberhard Nieschlag. "Cytologic investigation of human in vitro fertilization failures." Fertility and Sterility 43, no. 6 (June 1985): 883–91. http://dx.doi.org/10.1016/s0015-0282(16)48616-4.

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19

Wallach, Edward E., Soon-Chye Ng, Ariff Bongso, Henry Sathananthan, and Shan S. Ratnam. "Micromanipulation: its relevance to human in vitro fertilization." Fertility and Sterility 53, no. 2 (February 1990): 203–19. http://dx.doi.org/10.1016/s0015-0282(16)53267-1.

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20

Wikland, M., L. Hamberger, L. Enk, and L. Nilsson. "Sonographic techniques in human in-vitro fertilization programmes." Human Reproduction 3, suppl 2 (October 1, 1988): 65–68. http://dx.doi.org/10.1093/humrep/3.suppl_2.65.

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21

Bavister, B. D., D. L. Kinsey, M. Lane, and D. K. Gardner. "Recombinant human albumin supports hamster in-vitro fertilization." Human Reproduction 18, no. 1 (January 1, 2003): 113–16. http://dx.doi.org/10.1093/humrep/deg017.

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22

Lehner, Adam, Zita Kaszas, Akos Murber, Janos Rigo, Janos Urbancsek, and Peter Fancsovits. "Giant oocytes in human in vitro fertilization treatments." Archives of Gynecology and Obstetrics 292, no. 3 (March 10, 2015): 697–703. http://dx.doi.org/10.1007/s00404-015-3679-0.

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23

Gordon, Jon W., and Neri Laufer. "Applications of micromanipulation to human in vitro fertilization." Journal of In Vitro Fertilization and Embryo Transfer 5, no. 2 (April 1988): 57–60. http://dx.doi.org/10.1007/bf01130659.

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24

Ackerman, Steven B., Gordon L. Stokes, R. James Swanson, Sherry P. Taylor, and Lori Fenwick. "Toxicity testing for human in vitro fertilization programs." Journal of In Vitro Fertilization and Embryo Transfer 2, no. 3 (September 1985): 132–37. http://dx.doi.org/10.1007/bf01131499.

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25

Ceelen, Manon, and Jan P. W. Vermeiden. "Health of Human and Livestock Conceived by Assisted Reproduction." Twin Research 4, no. 5 (October 1, 2001): 412–16. http://dx.doi.org/10.1375/twin.4.5.412.

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AbstractAssisted reproduction is used to resolve infertility problems in human and in breeding programs to generate livestock. Except for gestation length and birth weight, perinatal outcome of children conceived by In Vitro Fertilization is similar to that of spontaneously conceived children. However, large offspring syndrome observed after In Vitro Production in livestock is quite alarming. The distinct parts of assisted reproduction (oocyte maturation, fertilization and culture) have been found to contribute to abnormal fetal growth and development. Genomic imprinting is suggested to be involved in the induction of the aberrant phenotypes observed after assisted reproduction. Furthermore, current knowledge on postnatal health of offspring conceived by assisted reproduction and speculations on potential longterm effects of In Vitro Fertilization will be described.
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26

Menezo, Yves, Patrice Clément, and Brian Dale. "DNA Methylation Patterns in the Early Human Embryo and the Epigenetic/Imprinting Problems: A Plea for a More Careful Approach to Human Assisted Reproductive Technology (ART)." International Journal of Molecular Sciences 20, no. 6 (March 17, 2019): 1342. http://dx.doi.org/10.3390/ijms20061342.

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An increasing number of publications indicate that babies born after IVF (in vitro fertilization) procedures have higher rates of anomalies related to imprinting/epigenetic changes, which may be attributed to suboptimal culture conditions. Appropriate maintenance of DNA methylation during the first few days of an in vitro culture requires a supply of methyl donors, which are lacking in current in vitro culture systems. The absence of protection against oxidative stress in the culture increases the risks for errors in methylation. A decrease in the methylation processes is sometimes observed immediately post fertilization, due to delays that occur during the maternal–zygotic transition period. Care should be exercised in ART (assisted reproductive technology) procedures in order to avoid the risk of generating errors in methylation during the in vitro culture period immediately post fertilization, which has an impact on imprinting/epigenetics. Formulation of IVF culture media needs to be re-assessed in the perspective of current knowledge regarding embryo physiology.
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27

Bongso, T. A., S. C. Ng, H. Mok, M. N. Lim, H. L. Teo, P. C. Wong, and S. S. Ratnam. "Effect of Sperm Motility on Human In Vitro Fertilization." Archives of Andrology 22, no. 3 (January 1989): 185–90. http://dx.doi.org/10.3109/01485018908986770.

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28

Bonnicksen, Andrea L. "HUMAN EMBRYO FREEZING AND IN VITRO FERTILIZATION: POLICY DIRECTIONS." Review of Policy Research 8, no. 2 (December 1988): 380–88. http://dx.doi.org/10.1111/j.1541-1338.1988.tb01109.x.

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29

Poindexter, Alfred, and Kevin Doody. "Advances in Human In Vitro Fertilization and Embryo Transfer." Seminars in Reproductive Medicine 3, no. 02 (May 1985): 201–10. http://dx.doi.org/10.1055/s-2007-1022617.

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30

Mouzon, Jacques de, Brigitte Lefèvre, René Frydman, Joelle-Glaire Belaisch-Allart, Frédérique Guillet-Rosso, and Jacques Testart. "Factors affecting human in vitro fertilization: a multifactorial study." Fertility and Sterility 43, no. 6 (June 1985): 892–96. http://dx.doi.org/10.1016/s0015-0282(16)48617-6.

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31

Wallach, Edward E., De Yi Liu, and H. W. Gordon Baker. "Tests of human sperm function and fertilization in vitro." Fertility and Sterility 58, no. 3 (September 1992): 465–83. http://dx.doi.org/10.1016/s0015-0282(16)55247-9.

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32

Fishel, Simon, Peter Jackson, John Webster, and Bahman Faratian. "Endotoxins in culture medium for human in vitro fertilization." Fertility and Sterility 49, no. 1 (January 1988): 108–11. http://dx.doi.org/10.1016/s0015-0282(16)59659-9.

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33

Zaninovic, Nikica, and Zev Rosenwaks. "Artificial intelligence in human in vitro fertilization and embryology." Fertility and Sterility 114, no. 5 (November 2020): 914–20. http://dx.doi.org/10.1016/j.fertnstert.2020.09.157.

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34

De Yi, Liu, and HWG Baker. "Tests of human sperm function and fertilization in vitro." International Journal of Gynecology & Obstetrics 41, no. 2 (May 1993): 208. http://dx.doi.org/10.1016/0020-7292(93)90715-9.

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35

DeCherney, Alan H., Basil C. Tarlatzis, and Neri Laufer. "Follicular development: Lessons learned from human in vitro fertilization." American Journal of Obstetrics and Gynecology 153, no. 8 (December 1985): 911–23. http://dx.doi.org/10.1016/0002-9378(85)90705-7.

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36

Gerrity, Marybeth. "Determinants of human embryo quality following in vitro fertilization." Theriogenology 37, no. 1 (January 1992): 147–60. http://dx.doi.org/10.1016/0093-691x(92)90252-m.

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37

Meldrum, David R. "Factors affecting embryo implantation after human in vitro fertilization." American Journal of Obstetrics and Gynecology 165, no. 6 (December 1991): 1896. http://dx.doi.org/10.1016/0002-9378(91)90057-x.

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38

Martin-Pont, Brigitte, Jacqueline Selva, Marianne Bergere, Corinne Pillion, Jean Noel Hugues, Agnès Tamboise, and Edmond Tamboise. "Chromosome analysis of multipronuclear human oocytes afterin vitro fertilization." Prenatal Diagnosis 11, no. 8 (August 1991): 501–7. http://dx.doi.org/10.1002/pd.1970110804.

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39

Sherwin, Susan. "Feminist Ethics and In Vitro Fertilization." Canadian Journal of Philosophy Supplementary Volume 13 (1987): 264–84. http://dx.doi.org/10.1080/00455091.1987.10715938.

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New technology in human reproduction has provoked wide ranging arguments about the desirability and moral justifiability of many of these efforts. Authors of biomedical ethics have ventured into the field to offer the insight of moral theory to these complex moral problems of contemporary life. I believe, however, that the moral theories most widely endorsed today are problematic and that a new approach to ethics is necessary if we are to address the concerns and perspectives identified by feminist theorists in our considerations of such topics. Hence, I propose to look at one particular technique in the growing repertoire of new reproductive technologies, in vitro fertilization (IVF), in order to consider the insight which the mainstream approaches to moral theory have offered to this debate, and to see the difference made by a feminist approach to ethics.
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40

Tilly, Jonathan L., and Dori C. Woods. "The obligate need for accuracy in reporting preclinical studies relevant to clinical trials: autologous germline mitochondrial supplementation for assisted human reproduction as a case study." Therapeutic Advances in Reproductive Health 14 (January 2020): 263349412091735. http://dx.doi.org/10.1177/2633494120917350.

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A now large body of work has solidified the central role that mitochondria play in oocyte development, fertilization, and embryogenesis. From these studies, a new technology termed autologous germline mitochondrial energy transfer was developed for improving pregnancy success rates in assisted reproduction. Unlike prior clinical studies that relied on the use of donor, or nonautologous, mitochondria for microinjection into eggs of women with a history of repeated in vitro fertilization failure to enhance pregnancy success, autologous germline mitochondrial energy transfer uses autologous mitochondria collected from oogonial stem cells of the same woman undergoing the fertility treatment. Initial trials of autologous germline mitochondrial energy transfer during - in vitro fertilization at three different sites with a total of 104 patients indicated a benefit of the procedure for improving pregnancy success rates, with the birth of children conceived through the inclusion of autologous germline mitochondrial energy transfer during in vitro fertilization. However, a fourth clinical study, consisting of 57 patients, failed to show a benefit of autologous germline mitochondrial energy transfer– in vitro fertilization versus in vitro fertilization alone for improving cumulative live birth rates. Complicating this area of work further, a recent mouse study, which claimed to test the long-term safety of autologous mitochondrial supplementation during in vitro fertilization, raised concerns over the use of the procedure for reproduction. However, autologous mitochondria were not actually used for preclinical testing in this mouse study. The unwarranted fears that this new study’s erroneous conclusions could cause in women who have become pregnant through the use of autologous germline mitochondrial energy transfer during- in vitro fertilization highlight the critical need for accurate reporting of preclinical work that has immediate bearing on human clinical studies.
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41

I’tishom, Reny, Doddy M. Soebadi, Aucky Hinting, Hamdani Lunardhi, and Rina Yudiwati. "IN VITRO FERTILITY TEST OF HUMAN SPERMATOZOA MEMBRANE PROTEIN FERTILIN BETA ANTIBODY IN MICE (Mus musculus Balb/c) AS IMMUNOCONTRACEPTIVE CANDIDATE." Folia Medica Indonesiana 52, no. 3 (August 14, 2017): 209. http://dx.doi.org/10.20473/fmi.v52i3.5453.

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One of the materials as potential candidates immunocontraception material is spermatozoa. Fertilin beta is spermatozoa membrane protein and is found only in mature spermatozoa and ejaculate, which serves as an adhesion molecule. Spermatozoa membrane protein that is used as an ingredient immunocontraception candidate, must have specific criteria that the specificity of spermatozoa, the role of antigen in the fertilization process, which includes the formation of immunogenicity sufficient antibody response has the potential to block fertilization. Antibodies against spermatozoa affect the stages before fertilization of the reproductive process and can hinder the development of the embryo after fertilization. Until now very little research data spermatozoa membrane protein as an ingredient immunocontraception are up to the test of experimental animals. The research objective is to prove the role of the resulting antibody induction of antibodies fertilin beta protein in the membrane of human spermatozoa induce agglutination and reduce motility thus reducing the number of in vitro fertilization. Research conducted at the IVF Laboratory, Department of Biology of Medicine, Faculty of Medicine, University of Airlangga. This research includes: Test the potential of antibody protein beta fertilin membrane of human spermatozoa and inhibit the role of antibodies in vitro fertilization in mice (Mus musculus Balb/c). In vitro studies have resulted in fertilization figure of 25% is smaller than the number that is equal to control fertilization of 58.7%, whereas previously the spermatozoa were incubated first with a beta membrane protein antibody fertilin human spermatozoa. While the percentage of inhibition of sperm to fertilize an oocyte by 33.75%. Potential imunokontraseptif considered effective if it decreased significantly (P <0.05) than the numbers fertilization in the treatment group compared with the control group. This shows fertilin beta membrane protein antibody has the ability to inhibit human spermatozoa to fertilize oocytes that reduce the number of fertilization.
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42

Muñoz, Michael G. "A Reexamination of In Vitro Fertilization." Christian bioethics: Non-Ecumenical Studies in Medical Morality 29, no. 1 (March 1, 2023): 21–30. http://dx.doi.org/10.1093/cb/cbad006.

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Abstract For the sake of consistency with settled principles from other theological and ethical questions, there is a need for a Christian reexamination of in vitro fertilization (IVF). Both Old and New Testaments demonstrate that human personal life begins at conception or fertilization. Additionally, the Bible teaches that human beings are persons in the image of God from the very beginning of their existence. Thus, it can be concluded that the embryos created via IVF are persons in God’s image. Applying this to the destruction and freezing of embryos, several limitations or restrictions present themselves—embryos should not be purposefully destroyed or wasted, all embryos ought to be implanted, and embryos should not be frozen. Ultimately, however, due to the immense quantity of embryo wastage, it is concluded that Christians should avoid this form of assisted reproductive technology and consider it a pro-life issue.
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43

Krisher, Rebecca L. "Present state and future outlook for the application of in vitro oocyte maturation in human infertility treatment." Biology of Reproduction 106, no. 2 (January 29, 2022): 235–42. http://dx.doi.org/10.1093/biolre/ioac010.

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Abstract In vitro oocyte maturation is an assisted reproductive technology in which a meiotically immature oocyte (prophase I or germinal vesicle stage) is recovered from an antral follicle and matured in vitro prior to fertilization. This technology, although in widespread use in domestic livestock, is not typically implemented during human in vitro fertilization cycles. This review examines how in vitro oocyte maturation is currently used in the clinical setting, including the various ways in vitro oocyte maturation is defined in practice. The role of in vitro oocyte maturation in patient care and the major challenges for implementation are described. Efficiency and safety are critically explored. The role of in vitro oocyte maturation in oncofertility will also be discussed. Finally, the outlook for the future of clinical in vitro oocyte maturation is considered.
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44

Lim, C. C., S. E. M. Lewis, M. Kennedy, E. T. Donnelly, and W. Thompson. "Human sperm morphology and in vitro fertilization: sperm tail defects are prognostic for fertilization failure." Andrologia 30, no. 1 (April 24, 2009): 43–47. http://dx.doi.org/10.1111/j.1439-0272.1998.tb01381.x.

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45

Ye, Hong, Guo-ning Huang, Yang Gao, and De Yi Liu. "Relationship between human sperm-hyaluronan binding assay and fertilization rate in conventional in vitro fertilization." Human Reproduction 21, no. 6 (April 4, 2006): 1545–50. http://dx.doi.org/10.1093/humrep/del008.

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46

Chan, Philip J., Gary S. Packin, Edward A. Slotnick, Wesley S. Chodos, Louis R. Manara, and Daniel H. Belsky. "Retarded cleavage following in vitro fertilization of mature human oocytes." Journal of the American Osteopathic Association 87, no. 5 (May 1, 1987): 99–104. http://dx.doi.org/10.1515/jom-1987-870510.

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47

Baker, HW, and DY Liu. "New tests of human sperm function and fertilization in vitro." Reproduction, Fertility and Development 1, no. 2 (1989): 179. http://dx.doi.org/10.1071/rd9890179.

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48

Dumoulin, J. C. M., J. L. H. Evers, J. P. M. Offermans, M. Bras, M. H. E. C. Pieters, and J. P. M. Geraedts. "Human in vitro Fertilization Using Spermatozoa Capacitated in Hyperosmotic Media." Gynecologic and Obstetric Investigation 30, no. 3 (1990): 165–68. http://dx.doi.org/10.1159/000293254.

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49

Eriksen, Gitte V., Anders Malmström, and Niels Uldbjerg. "Human follicular fluid proteoglycans in relation to in vitro fertilization." Fertility and Sterility 68, no. 5 (November 1997): 791–98. http://dx.doi.org/10.1016/s0015-0282(97)00326-9.

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50

Miller, Nora R., and Nanette Santoro. "Human immunodeficiency virus positive women treated with in vitro fertilization." Fertility and Sterility 80 (September 2003): 134. http://dx.doi.org/10.1016/s0015-0282(03)01232-9.

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