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Journal articles on the topic 'Ferulago Angulata'

Author: Grafiati
Published: 4 June 2025
Last updated: 23 June 2025

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1

Hajhashemi, Valiollah, Samira Rafieian Kopaei, and Seyed Ebrahim Sajjadi. "Anti-nociceptive and anti-inflammatory effects of Ferulago angulata." Immunopathologia Persa 6, no. 2 (2020): e28-e28. http://dx.doi.org/10.34172/ipp.2020.28.

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Introduction: Ferulago angulata from the Apiaceae family, has high flavonoid content and is detected to have anti-nociceptive and anti-inflammatory effects. Objectives: In this study, we sought to determine the components of essential oil and to estimate total phenol and flavonoid contents of its various extracts. We also aimed to find out the anti-nociceptive and anti-inflammatory effects of essential oil, hydro-alcoholic and phenolic extracts of F. angulata aerial parts. Materials and Methods: The plant’s essential oil and extracts were prepared according to standard methods. Acetic acid, hot plate and formalin tests were used to investigate anti-nociceptive effects. Additionally, carrageenan and croton oil tests were used to evaluate anti-inflammatory effects. Results: Ferulago angulata aerial parts yielded 0.2% (v/w) yellowish essential oil. The gas chromatography/ mass spectrometry (GC-MS) of essential oil identified 82 compounds, which represented 98.9% of the essential oil. Thymol (7.9%), spathulenol (6.5%), trans-anethol (6.4%), myristicin (5.1%) and alpha-pinene (4.5%) were the main components. In acetic acid and formalin tests, the essential oil, hydro-alcoholic and phenolic extracts showed significant anti-nociceptive effects (P<0.001). In hot plate test, morphine which was used as standard drug, revealed significant anti-nociceptive effect while the plant extracts and essential oil were ineffective. High dose of the extracts and essential oil in croton oil test (P<0.001) and high dose of hydro-alcoholic and phenolic extracts in carrageenan test (P<0.05) reduced the inflammation. Conclusion: Ferulago angulata extracts and essential oil have anti-nociceptive and anti-inflammatory effects. However, further studies are needed to clarify their mechanism of actions.
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2

., Masumeh Khanahmadi, and Kamran Janfeshan . "Study on Antioxidation Property of Ferulago angulata Plant." Asian Journal of Plant Sciences 5, no. 3 (2006): 521–26. http://dx.doi.org/10.3923/ajps.2006.521.526.

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3

Pajohi Alamoti, Mohammadreza, Behnaz Bazargani-Gilani, Razzagh Mahmoudi, et al. "Essential Oils from Indigenous Iranian Plants: A Natural Weapon vs. Multidrug-Resistant Escherichia coli." Microorganisms 10, no. 1 (2022): 109. http://dx.doi.org/10.3390/microorganisms10010109.

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Aim of this study was to investigate the antimicrobial properties of herbal plant essential oils (EOs) from selected Iranian plant species such as Ferulago angulata, Zataria multiflora, Cuminum cyminum, and Mentha longifolia against antibiotic-resistant Escherichia coli (E. coli) strains. For this purpose, the Escherichia coli strains, isolated from raw cow’s milk and local dairy products (yogurt, cream, whey, cheese, and confectionery products) collected from different areas of Hamedan province, Iran, were investigated for their resistance to antibiotics (i.e., streptomycin, tetracycline, gentamicin, chloramphenicol, ciprofloxacin, and cefixime). Thus, the E. coli strains were tested for their susceptibility to the above-mentioned essential oils. Regarding antibiotics, the E. coli strains were highly sensitive to ciprofloxacin. In relation to essential oils, the most effective antibacterial activity was observed with Zataria multiflora; also, the bacteria were semi-sensitive to Cuminum cyminum and Mentha longifolia essential oils. All strains were resistant to Ferulago angulata essential oil. According to the results, the essential oil of Zataria multiflora can be considered as a practical and alternative antibacterial strategy to inhibit the growth of multidrug-resistant E. coli of dairy origin.
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4

Bohlouli, Somayeh, and Ehsan Sadeghi. "Growth performance and haematological and immunological indices of rainbow trout (Oncorhynchus mykiss) fingerlings supplemented with dietary Ferulago angulata (Schlecht) Boiss." Acta Veterinaria Brno 85, no. 3 (2016): 231–38. http://dx.doi.org/10.2754/avb201685030231.

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In this study, the effects of Ferulago angulata extract on the growth, haematological, and immunological indices of rainbow trout (Oncorhynchus mykiss) fingerlings were evaluated. Basal diet was supplemented with 0 (control), 0.5, 1, and 2 g·kg-1 F. angulata and was randomly allocated to experimental fish of an initial average weight of 7.45 ± 0.02 g. After 8 weeks of experiment, the fish supplemented with F. angulata extract showed increased but non-significant (P > 0.05) growth performance. No significant differences were found between trial control groups in haematological indices such as red blood cell count, haematocrit, and haemoglobin, but there was a significant increase in white blood cells, lymphocytes, neutrophils and monocytes in the F. angulata extract groups (P < 0.05). Also, there were significant differences between the fish supplemented with dietary F. angulata extract and the control group regarding immunological indices, including immunoglobulin M, lysozyme, and classical and alternative complement pathway (P < 0.05). These findings suggest that the administration of F. angulata extract has a positive effect on the immunological indices and the immune system activity in rainbow trout fingerling.
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5

Sodeifian, Gholamhossein, and Karamat Ansari. "Optimization of Ferulago Angulata oil extraction with supercritical carbon dioxide." Journal of Supercritical Fluids 57, no. 1 (2011): 38–43. http://dx.doi.org/10.1016/j.supflu.2011.02.002.

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6

Mirzaghai, Somaye, Hassan Akrami, Kamran Mansouri, and Hossein Fallahi. "Anti-angiogenic activity of ethanol extracts of Ferulago angulata leaves." Clinical Biochemistry 44, no. 13 (2011): S115. http://dx.doi.org/10.1016/j.clinbiochem.2011.08.279.

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7

Parsamehr, Rahil, and Somayeh Bohlouli. "The effect of Ferulago angulata (Schelchet) Boiss on blood glucose levels and suppression of diabetes in rats." Acta Veterinaria Brno 88, no. 3 (2019): 349–54. http://dx.doi.org/10.2754/avb201988030349.

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Diabetes mellitus is a metabolic disease characterized by elevated blood glucose levels. Medicinal plant Ferulago angulata has anti-oxidant properties. The aim of the present research was to evaluate the effect of a hydroalcoholic extract of F. angulata on the blood glucose level and liver enzyme activity in diabetic male rats. Forty-eight male rats were randomly divided into eight groups, including normal and diabetic groups. Diabetes was induced by a single intraperitoneal injection of streptozotocin at 40 mg·kg-1 body weight. Rats were treated with an intraperitoneal injection of the extract for three weeks. At the end of the experimental period, fasting blood samples were collected, and blood glucose and liver enzyme activity were measured. This study demonstrated that serum glucose levels in diabetic groups treated with F. angulata were significantly lower than those in diabetic rats (P < 0.001). Alanine aminotransferase levels in diabetic rats treated with F. angulata were significantly decreased compared to diabetic rats (P < 0.001). Aspartate aminotransferase levels in diabetic rats treated with 200 and 400 mg·kg-1 F. angulata were significantly decreased compared to diabetic rats (P < 0.001). No significant differences were observed in the serum levels of blood glucose and liver enzymes in the normal group treated with different doses of the extract. These results show that the hydroalcoholic extract of F. angulata might be effective in the treatment of diabetes and consequently alleviate the liver damage caused by streptozotocin-induced diabetes mellitus. This effect might be due to the presence of flavonoids and their antioxidant features.
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8

Pirbalouti, Abdollah Ghasemi, Leila Sedaghat, Behzad Hamedi, and Farhang Tirgir. "Chemical composition and antioxidant activity of essential oils of three endemic medicinal plants of Iran." Bangladesh Journal of Botany 42, no. 2 (2014): 327–32. http://dx.doi.org/10.3329/bjb.v42i2.18038.

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Hydro-distillated essential oils (EO) antioxidant activity of three endemic medicinal plants of Iran namely, Heracleum lasiopetalum Boiss., Kelussia odoratissima Mozaff., and Ferulago angulata (Schlecht.) Boiss were studied. The results indicated that the major components of the EOs were 2-ethylhexyl acetate (34.5%), n-octanol (6.5%), and hexanol (5.1%) for H. lasiopetalum fruits; Z-?-ocimene (20.5), ?-pinene (11.6%), and ?-phellandrene (9.3) for F. angulata aerial parts; ?-pinene (20.1%), 1,8-cineole (18.2%), and Zligustilide (15.5%) for K. odoratissima aerial parts. The three EOs having high antioxidant activity could be used as an alternative preservative instead of synthetic ones in food industry. DOI: http://dx.doi.org/10.3329/bjb.v42i2.18038 Bangladesh J. Bot. 42(2): 327-332, 2013 (December)
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9

Azizi, Maliheh, Fatemeh Fazeli, Mehrdad Mohammadi, and Amin Mousavi Khaneghah. "Incorporation of essential oils in Iranian traditional animal oil: an assessment of physicochemical and sensory assessment." Italian Journal of Food Science 33, SP1 (2021): 69–77. http://dx.doi.org/10.15586/ijfs.v33isp1.2027.

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This study aimed to incorporate the herbal essential oils (Ziziphora tenuior L. (Z. tenuior), Ferulago angulata (F. angulata), and Bunium persicum (B. persicum)) all in three levels (5, 7, and 10% w/w) and tertiary butyl hydroquinone (100, 200, and 300 ppm) to evaluate the oxidation stability of Iranian animal oil (IAO). Z. tenuior, F. angulata, and B. persicum (5, 7, and 10% w/w) and tertiary butyl hydroquinone (100, 200, and 300 ppm) were added to IAO. The physicochemical properties and color analysis, and sensory characteristics (odor, taste, rancidity, and overall acceptability) of the treatments were investigated on days 0, 7, 14, 21, and 28. The results showed that increasing the amounts of Z. tenuior, F. angulata, and B. persicum was associated with reducing acid, peroxide, and thiobarbituric acid values. It also lowered brightness and yellowness while the oxidative stability of the IAO significantly was increasing. It was concluded that the incorporation of B. persicum had the highest effectiveness regarding the proposed criteria with the least effect on sensory properties.
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10

Farokhi-Firoozi, Hedieh, Mahtab Rahavi, Morteza Pirali-Hamedani, Abbas Hadjiakhundi, and Mohammad-Reza Delnavazi. "Essential Oil Analysis and Isolation of Coumarins and Flavonol Glycosides of Ferulago angulata (Schltdl.) Boiss. Fruits." Pharmaceutical Sciences 27, no. 1 (2020): 139–46. http://dx.doi.org/10.34172/ps.2020.49.

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Background: Ferulago angulata (Schltdl.) Boiss. is a herbaceous perennial plant distributed in Iran, Turkey and Iraq. The aromatic aerial parts of this plant are commonly used as antiseptic, sedative, wound healing, analgesic and food additive. Methods: Column chromatography on silica gel (normal phase and RP-18) and Sephadex LH-20, along with recrystallization method were applied to isolation of the phytochemicals extracted from F. angulata fruits. The structures of the isolated compounds were characterized by 1H-NMR and 13C-NMR spectral analysis. Chemical composition of the fruits essential oil obtained by hydrodistillation (HD) and steam distillation (SD) methods were also analyzed using GC-MS technique. Results: Six coumarin derivatives; suberosin (1), isoimperatorin (2), imperatorin (3), bergapten (4), tamarin (5) and suberenol (6), a monoterpene glycoside; verbenone-5-O-β-D-glucopyranoside (7), together with five flavonol-3-O-glycosides; isorhamnetin-3-O-rutinoside (narcissin) (8), kaempferol-3-O-rutinoside (nicotiflorin) (9), quercetin-3-O-rutinoside (rutin) (10), isorhamnetin-3-O-β-D-glucuronide (11), isorhamnetin-3-O-β-D-glucopyranoside (12) were isolated from F. angulata fruits. Essential oil extraction using HD and SD methods afforded colorless oils in 4.1 and 1.8% (v/w) yields, respectively. A total of 28 compounds were identified in essential oils, of which (Z)-β-ocimene (HD; 48.97%, SD; 50.02%), α-pinene (HD; 21.32%, SD; 23.06%) and allo-ocimene (HD; 6.98%, SD; 5.61%) were the main compounds. Conclusion: This study introduces F. angulata fruits as a new source of coumarin derivatives and flavonoid glycosides. The presence of these compounds with known biological properties provides more medicinal potentials for the fruits of F. angulata. The present study also reports hydrodistillation, as an efficient method for extraction of essential oil from these aromatic fruits.
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11

Lorigooini, Zahra, Masomeh Koravand, Hedayat Haddadi, Mahmoud Rafieian-Kopaei, Hamzeh Ali Shirmardi, and Zohreh Hosseini. "A review of botany, phytochemical and pharmacological properties of Ferulago angulata." Toxin Reviews 38, no. 1 (2017): 13–20. http://dx.doi.org/10.1080/15569543.2017.1399277.

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12

Mollaei, Saeed, Farzaneh Sedighi, Biuck Habibi, Saeid Hazrati, and Parina Asgharian. "Extraction of essential oils of Ferulago angulata with microwave-assisted hydrodistillation." Industrial Crops and Products 137 (October 2019): 43–51. http://dx.doi.org/10.1016/j.indcrop.2019.05.015.

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13

Heidari, Shafagh, Hassan Akrami, and Hamid Mahdiuni. "Study of Chemopreventive activity of ethanolic extract of Ferulago angulata leaves." Clinical Biochemistry 44, no. 13 (2011): S339. http://dx.doi.org/10.1016/j.clinbiochem.2011.08.843.

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14

Mohammadi, Mehrdad, Nasim Khorshidian, and Seyed Mohammad Taghi Gharibzahedi. "The Extended Oxidative and Sensory Stability of Traditional Dairy-Based Oil with Steam-Distilled Essential Oils Extracted from the Bioactive-Rich Leaves of Ziziphora tenuior, Ferulago angulata, and Bunium persicum." Journal of Food Quality 2021 (May 24, 2021): 1–9. http://dx.doi.org/10.1155/2021/6613198.

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The oxidation rate and overall sensory acceptability of Iranian animal oil (IAO) during storage were evaluated after adding the bioactive essential oils extracted from medicinal herbs of Ziziphora tenuior, Ferulago angulata, and Bunium persicum. Results showed that the most dominant chemical constituents in Z. tenuior, F. angulata, and B. persicum essential oils were pulegone (12.77%), ferulagon (14.97%), and (+)-trans-carveol (57.70%), respectively. IAO contained more saturated fatty acids (67.43%, mainly palmitic and myristic acids) than unsaturated (32.27%, mostly oleic acid) ones. B. persicum essential oil compared to the other two oils significantly had more total flavonoid (1.08 mg quercetin equivalent/g), phenolic (123.2 mg GAE/g), carotenoid (591.31 mg/kg), and chlorophyll (24.32 mg/kg) contents. A significant dose-dependent increase in the overall sensory acceptability of IAO was found by increasing the concentration of B. persicum essential oil. Similar to tertiary butyl hydroquinone, the oil blend of IAO+10% B. persicum essential oil obtained the maximum overall sensory acceptability scores during 28 d cold storage due to the remarkable in vitro DPPH inhibition (83.45%) and ferric-reducing power (0.754 at Å700nm). A much slower formation rate in primary and secondary oxidation compounds in IAO rich in B. persicum essential oil during the storage was associated with the overall sensory acceptability data ( p < 0.01 , r = 0.951). Thus, this bioactive additive as a bio-preservative may well stabilize crude oils and emulsions.
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15

Sajjadi, SeyedEbrahim, Abbas-Ali Eskandarian, Yalda Shokoohinia, et al. "Antileishmanial activity of prenylated coumarins isolated from Ferulago angulata and Prangos asperula." Research in Pharmaceutical Sciences 11, no. 4 (2016): 324. http://dx.doi.org/10.4103/1735-5362.189314.

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Naderi, Nushin, Mehdi Hajian, Manouchehr Souri, Mohammad Hossein Nasr Esfahani, and Nima Tanhaei Vash. "Addition of Ferulago Angulata Extract To Freezing Extender For Goat Sperm Cryopreservation." Cryobiology 103 (December 2021): 202. http://dx.doi.org/10.1016/j.cryobiol.2021.11.150.

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17

Akhlaghi, Hashem. "The essential oils from flowers, stems and leaves of Ferulago angulata from Iran." Chemistry of Natural Compounds 44, no. 3 (2008): 396–97. http://dx.doi.org/10.1007/s10600-008-9076-1.

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18

Moghaddam, Mohammad, Leila Mehdizadeh, Hossein Mirzaei Najafgholi, and Abdollah Ghasemi Pirbalouti. "Chemical composition, antibacterial and antifungal activities of seed essential oil of Ferulago angulata." International Journal of Food Properties 21, no. 1 (2018): 158–70. http://dx.doi.org/10.1080/10942912.2018.1437626.

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Naderi, Nushin, Manouchehr Souri, Mohammad Hossein Nasr Esfahani, Mehdi Hajian, and Nima Tanhaei Vash. "Ferulago angulata extract ameliorates epididymal sperm toxicity in mice induced by lead and diazinon." Andrology 8, no. 3 (2020): 706–18. http://dx.doi.org/10.1111/andr.12730.

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Sadeghi, Ehsan, Aidin Mahtabani, Alireza Etminan, and Farahnaz Karami. "Stabilization of soybean oil during accelerated storage by essential oil of ferulago angulata boiss." Journal of Food Science and Technology 53, no. 2 (2015): 1199–204. http://dx.doi.org/10.1007/s13197-015-2078-7.

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21

Shahbazi, Yasser, Nassim Shavisi, Negin Karami, and Shabnam Kakaei. "Chemical composition and in vitro antibacterial activity of Ferulago angulata (Schlecht.) Boiss essential oil." Pharmaceutical Sciences 21, no. 1 (2015): 6–11. http://dx.doi.org/10.15171/ps.2015.10.

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Naderi, Nushin, Manouchehr Souri, Mohammad Hossein Nasr-Esfahani, Mehdi Hajian, and Mohammad Naser Nazem. "Ferulago angulata extract alleviates testicular toxicity in male mice exposed to diazinon and lead." Tissue and Cell 85 (December 2023): 102257. http://dx.doi.org/10.1016/j.tice.2023.102257.

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Kızıltaş, Hatice, Suat Ekin, Mahire Bayramoğlu Akkoyun, Gökhan Oto, and Esvet Akbaş. "Protective effect of Ferulago angulata (Schlecht.) Boiss on N-nitrosodimethylamine induced oxidative stress in rats." Eastern Journal Of Medicine 24, no. 2 (2019): 117–22. http://dx.doi.org/10.5505/ejm.2019.85866.

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Razavi, Seyed Mehdi, Ameneh Ravansalar, and Shahabeddin Mirinejad. "The investigation on phytochemicals from Ferulago angulata (Schlecht) Boiss, indigenous to central parts of Iran." Natural Product Research 29, no. 21 (2015): 2037–40. http://dx.doi.org/10.1080/14786419.2015.1017725.

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Parvar, Reza, Taghi Ghoorchi, Hamed Kashfi, and Karim Parvar. "Effect of Ferulago angulata (Chavil) essential oil supplementation on lamb growth performance and meat quality characteristics." Small Ruminant Research 167 (October 2018): 48–54. http://dx.doi.org/10.1016/j.smallrumres.2018.07.026.

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Mumivand, Hasan, Avin Aghemiri, Asrin Aghemiri, Mohammad Reza Morshedloo, and Kianoush Nikoumanesh. "Ferulago angulata and Tetrataenium lasiopetalum: Essential oils composition and antibacterial activity of the oils and extracts." Biocatalysis and Agricultural Biotechnology 22 (November 2019): 101407. http://dx.doi.org/10.1016/j.bcab.2019.101407.

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Shahbazi, Yasser. "Variation in Chemical Composition of Essential Oil of Ferulago angulata Collected from West Parts of Iran." Pharmaceutical Sciences 22, no. 1 (2016): 16–21. http://dx.doi.org/10.15171/ps.2016.04.

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Borhanpour, Fatemeh, Seyed Saeed Sekhavatizadeh, Saeid Hosseinzadeh, Mahboobeh Hasanzadeh, Mohammad-Taghi Golmakani, and Morteza Moharreri. "Effect of microencapsulated chavil (Ferulago angulata) extract on physicochemical, microbiological, textural and sensorial properties of UF-feta-type cheese during storage time." International Journal of Food Engineering 18, no. 1 (2021): 53–66. http://dx.doi.org/10.1515/ijfe-2021-0198.

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Abstract Chavil (Ferulago angulata) extract (CE) and microencapsulated chavil extract (MCE) were added to UF- Feta-type Cheese. The aim of this study was to comprising CE and MCE on physicochemical and microbiological properties in cheese. The scanning electron microscope images demonstrate the MCE had elliptical shape. The average size diameter curve of the MCE revealed bimodal distribution with two peaks (1541 and 2222 nm) separately. The hardness value of MCE cheese (212.83 ± 17.63 g) was lower than that of CE (343.67 ± 25.53 g) because of canola oil used in the microencapsulation process. The MCE-cheese showed lower values of acidity (1.67%) in comparison with CE-cheese (1.87%). The viable numbers of Streptococcus thermophilus and Lactococcus lactis were equal among the samples (4.6–4.9 log10 CFU/g respectively). The acid degree value of MCE (2.07 ± 0.21%) and CE (1.83 ± 0.25%) cheese were nearly equal at the end of storage time.
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Hritcu, Lucian, Eyup Bagci, Emel Aydin, and Marius Mihasan. "Antiamnesic and Antioxidants Effects of Ferulago angulata Essential Oil Against Scopolamine-Induced Memory Impairment in Laboratory Rats." Neurochemical Research 40, no. 9 (2015): 1799–809. http://dx.doi.org/10.1007/s11064-015-1662-6.

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hazrati, Saeid, Mohammad-Taghi Ebadi, Saeed Mollaei, and Sara Khurizadeh. "Evaluation of volatile and phenolic compounds, and antioxidant activity of different parts of Ferulago angulata (schlecht.) Boiss." Industrial Crops and Products 140 (November 2019): 111589. http://dx.doi.org/10.1016/j.indcrop.2019.111589.

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Kiziltas, Hatice, Suat Ekin, Mahire Bayramoglu, et al. "Antioxidant properties of Ferulago angulata and its hepatoprotective effect against N-nitrosodimethylamine-induced oxidative stress in rats." Pharmaceutical Biology 55, no. 1 (2017): 888–97. http://dx.doi.org/10.1080/13880209.2016.1270974.

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Naderi, Nushin, Mehdi Hajian, Manouchehr Souri, Mohammad Hossein Nasr Esfahani, and Nima Tanhaei Vash. "Ferulago angulata extract improves the quality of buck spermatozoa post-thaw and counteracts the harmful effects of diazinon and lead." Cryobiology 98 (February 2021): 17–24. http://dx.doi.org/10.1016/j.cryobiol.2021.01.008.

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Mousavi-Ezmareh, Seyedeh-Fatemeh, Mohammad Mazani, Esfandiar Heidarian, et al. "The Effect of Hydroalcoholic Extract of Ferulago angulata on Liver Function Parameters and Antioxidant Status in Alloxan-Induced Diabetic Rats." European Journal of Medicinal Plants 20, no. 2 (2017): 1–9. http://dx.doi.org/10.9734/ejmp/2017/35134.

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Mahmoudi, Razieh, Maryam Rafieirad, and Samira Goudarzi. "Effect of Hydroalcoholic Extract of Ferulago angulata (Schlecht) Boiss on Motor and Memory Disorders in Animal Model of Parkinson Disease." Qom Univ Med Sci J 12, no. 8 (2018): 36–47. http://dx.doi.org/10.29252/qums.12.8.36.

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Farzaei, MohammadHosein, Fatemeh Farzaei, Fatemeh Heydarpour, ZahraMinush Siavash Haghighi, Zahra Abbasabadi, and Ehsan Sadeghi. "Protective effect of Ferulago angulata (Schltdl.) Boiss. hydroalcoholic extract against acetic acid-induced colitis in rat: Role of pro-inflammatory cytokines." Pharmacognosy Research 10, no. 4 (2018): 391. http://dx.doi.org/10.4103/pr.pr_9_18.

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Nazari Serenjeh, Fariba, Payman Hashemi, Fahimeh Rasolzadeh, Saeed Farhadi, and Akram-Alsadat Hoseini. "Magnetic fiber headspace solid-phase microextraction of Ferulago angulata volatile components using Preyssler‐type polyoxometalate/metal–organic framework/silica aerogel sorbent." Food Chemistry 373 (March 2022): 131423. http://dx.doi.org/10.1016/j.foodchem.2021.131423.

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Valipour, Aliasghar, Iman Zakavi, Shila Nayebifar, and Elham Ghasemi. "Anti-inflammatory properties of combined aquatic extract of Ferulago angulata boiss with aerobic exercise on pro-inflammatory indices in obese males." Journal of Research in Medical Sciences 25, no. 1 (2020): 86. http://dx.doi.org/10.4103/jrms.jrms_475_19.

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Alami-Rostami, Shahrbanoo, and Maryam Rafieirad. "The effect of hydro-alcoholic Ferulago angulata extract on locomotor activity and anxiety caused by hypoperfusion ischemia in adult male rats." Journal of Herbmed Pharmacology 7, no. 1 (2017): 51–55. http://dx.doi.org/10.15171/jhp.2018.09.

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Bohlouli, Somayeh, Ali Ghanbari, and GlavizhRostami Nassab. "Therapeutic effect of Ferulago angulata extract on reproductive parameters and serum testosterone levels in diabetic male rats." Journal of Reports in Pharmaceutical Sciences 7, no. 1 (2018): 1. http://dx.doi.org/10.4103/2322-1232.222727.

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Asghari, Jila. "Comparison of the Microwave-Assisted Hydrodistillation with the Traditional Hydrodistillation Method in the Extraction of Essential Oils from Ferulago angulata (Schelcht.) Boiss." European Journal of Medicinal Plants 2, no. 4 (2012): 324–34. http://dx.doi.org/10.9734/ejmp/2012/1488.

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AGHAJANI, Abdoreza, Seyed Ali MORTAZAV, Farideh TABTABAI YAZDI, Masoud SHAFAFI ZENOSIAN, and Mohammad Reza SAEIDI ASL. "Color, microbiological and sensory properties of low–fat probiotic yogurt supplemented with Spirulina platensis and Ferulago angulata hydroalcoholic extracts during cold storage." Banat's Journal of Biotechnology X, no. 19 (2019): 20–34. http://dx.doi.org/10.7904/2068-4738-x(19)-20.

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Alizadeh, Leyla, Khadije Abdolmaleki, Kooshan Nayebzadeh, and Reyhane Shahin. "Effects of tocopherol, rosemary essential oil and Ferulago angulata extract on oxidative stability of mayonnaise during its shelf life: A comparative study." Food Chemistry 285 (July 2019): 46–52. http://dx.doi.org/10.1016/j.foodchem.2019.01.028.

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Akbari, Sholeh, Maliheh Soodi, Homa Hajimehdipoor, and Nasim Ataei. "Protective effects of Sanguisorba minor and Ferulago angulata total extracts against beta-amyloid induced cytotoxicity and oxidative stress in cultured cerebellar granule neurons." Journal of Herbmed Pharmacology 8, no. 3 (2019): 248–55. http://dx.doi.org/10.15171/jhp.2019.36.

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Abstract:
Introduction: Alzheimer’s disease (AD) is an age-dependent neurodegenerative disorder and major cause of mortality in the elderly. AD has a complex pathophysiology and needs new multi-targeted compounds to halt the disease progression through several mechanisms. Medicinal plants contain various compounds with heterogeneous pharmacological effects, therefore are a good source. The aim of this study was to evaluate the protective effect of total extracts of Sanguisorba minor and Ferulago angulata on beta-amyloid (Aβ)-induced toxicity in primary neural cell culture.Methods: Cerebellar granule neurons (CGNs) were cultured according to standard protocols. The cultured neurons were incubated with Aβ alone or in combination with different concentrations of extracts for 24 hours. Cell viability was measured by methylthiazolyldiphenyl-tetrazolium (MTT) assay. In addition acetylcholinesterase (AChE) activity and oxidative stress markers were measured after incubation. Also, the effects of different concentrations of the extracts on AChE activity of the cultured neurons were investigated. For measuring the acute toxicity of the extract, LD50 was estimated by limit test.Results: Both extracts could protect CGNs against Aβ-induced cell death. Aβ-induced oxidative stress and increase of AChE activity were ameliorated by both extracts. S. minor extract dose-dependently reduced AChE activity in cultured CGNs. LD50 of both extracts was estimated above 2000 mg/kg and considered as safe.Conclusion: Both studied extracts protected CGNs against Aβ-induced toxicity by ameliorating oxidative stress mechanism. According to these results, these extracts are recommended for further investigation in AD treatment.
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Sodeifian, Gholamhossein, Seyed Ali Sajadian, and Nedasadat Saadati Ardestani. "Evaluation of the response surface and hybrid artificial neural network-genetic algorithm methodologies to determine extraction yield of Ferulago angulata through supercritical fluid." Journal of the Taiwan Institute of Chemical Engineers 60 (March 2016): 165–73. http://dx.doi.org/10.1016/j.jtice.2015.11.003.

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Sadeghi, Ghorbanali, Mahmood Habibian, Ali Raei, Danial Farhadi, and Naser Khateri. "Effects of dietary supplementation of Ferulago angulata (Schlecht.) Boiss powder on growth performance, carcass characteristics, and gut microflora and pH in broiler chicks." Comparative Clinical Pathology 25, no. 2 (2015): 257–63. http://dx.doi.org/10.1007/s00580-015-2175-z.

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Kianipour, Arezou, Zahra Baghaeifar, Hamid Darvishnia, and Shahriar Saeidian. "A Comparative Study of Total Phenolic, Total Flavonoid Contents and Antioxidant Capacity of Aerial Parts Extracts of Ferulago angulata in Different Developmental Stages." Journal of Crop Breeding 15, no. 47 (2023): 165–73. http://dx.doi.org/10.61186/jcb.15.47.165.

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Hamidian, Mohammad, Amin Salehi, Reza Naghiha, et al. "Biological activity of essential oils from Ferulago angulata and Ferula assa-foetida against food-related microorganisms (antimicrobial) and Ephestia kuehniella as a storage pest (insecticidal); an in vitro and in silico study." Fitoterapia 175 (June 2024): 105937. http://dx.doi.org/10.1016/j.fitote.2024.105937.

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Rostami, Farhad, Hossein A. Ghasemi, and Kamran Taherpour. "Effect of Scrophularia striata and Ferulago angulata, as alternatives to virginiamycin, on growth performance, intestinal microbial population, immune response, and blood constituents of broiler chickens." Poultry Science 94, no. 9 (2015): 2202–9. http://dx.doi.org/10.3382/ps/pev198.

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Shokri, Sajad, Karim Parastouei, Maryam Taghdir, and Sepideh Abbaszadeh. "Application an edible active coating based on chitosan- Ferulago angulata essential oil nanoemulsion to shelf life extension of Rainbow trout fillets stored at 4 °C." International Journal of Biological Macromolecules 153 (June 2020): 846–54. http://dx.doi.org/10.1016/j.ijbiomac.2020.03.080.

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Panahi, Zahra, and Mohammad Mohsenzadeh. "Sodium alginate edible coating containing Ferulago angulata (Schlecht.) Boiss essential oil, nisin, and NaCl: Its impact on microbial, chemical, and sensorial properties of refrigerated chicken breast." International Journal of Food Microbiology 380 (November 2022): 109883. http://dx.doi.org/10.1016/j.ijfoodmicro.2022.109883.

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