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Dissertations / Theses on the topic 'Fibrosis Assessment'

Author: Grafiati

Published: 25 May 2024

Last updated: 31 July 2025

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1

Meloff, Liann Rachel. "Assessment of eating disorder symptomatology in patients with cystic fibrosis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/NQ64876.pdf.

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2

Bradley, Judith. "The assessment of disability and handicap in adult cystic fibrosis." Thesis, University of Ulster, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311617.

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3

Jaffe, Adam. "Assessment and feasibility of gene therapy for cystic fibrosis in children." Thesis, Imperial College London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589769.

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4

Adam, Ryan John. "Quantitative morphologic assessment of the newborn cystic fibrosis pig tracheal lobe." Thesis, University of Iowa, 2012. https://ir.uiowa.edu/etd/2807.

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Cystic fibrosis (CF) is an inherited disease leading to disrupted function of the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel. CF affects many organ systems including the pancreas, liver, intestine, sweat glands, and gallbladder. The leading cause of morbidity and mortality, however, is lung disease. A porcine model of CF was developed, and over time it develops lung disease that recapitulates many of the characteristics observed in humans with CF including airway remodeling, mucus accumulation

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Adam, Ryan J. "Radiographic assessment of lung anatomy, physiology, and disease in a porcine model of cystic fibrosis and people with cystic fibrosis." Diss., University of Iowa, 2017. https://ir.uiowa.edu/etd/5692.

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Despite affecting many organ systems, the leading cause of morbidity and mortality in the cystic fibrosis (CF) population is lung disease. For the current studies we investigated elements of CF lung disease in a porcine model of CF and in people with CF. Our primary analysis tool was chest computed tomography (CT). To investigate early CF lung disease we examined three week old CF and non-CF pigs. We found three week old CF pigs to have large, irregular tracheal smooth muscle bundles, airways of reduced size, airways of irregular shape, and airways of abnormal distensibility. Three week old CF

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6

Olveda, David Brian Uy. "Assessment of Schistosomiasis Induced Morbidity in the Philippines." Thesis, Griffith University, 2017. http://hdl.handle.net/10072/368011.

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Schistosomiasis is a water-borne tropical disease plaguing approximately 240 million people worldwide. Approximately 3-70 million disability-adjusted life years are lost due to the disease. In the Philippines, schistosomiasis japonica is currently endemic in 28 provinces, 190 municipalities, and 2230 barangays (villages). Approximately 12 million residents of these endemic areas are vulnerable to infection. Preventive chemotherapy with praziquantel has been the cornerstone for schistosomiasis control in the country. The current national control program comprises annual free mass drug administr

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7

Guha, Indra Neil. "Exploring the diagnostic tools for the assessment of liver fibrosis using biofluids." Thesis, University of Southampton, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.443044.

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8

Gangell, Catherine Louise. "Evaluation of the forced oscillation technique for clinical assessment of young children with cystic fibrosis." University of Western Australia. School of Paediatrics and Child Health, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0213.

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Background: Measurements of lung function are routinely used in patients with cystic fibrosis (CF) to provide information that may be clinically relevant. Spirometry is the conventional lung function measurement used, however young children find spirometry difficult to perform and often cannot achieve the strict acceptability criteria for the test. The forced oscillation technique (FOT) is a lung function measurement that only requires tidal breathing and is easy for young children to perform. However, there is limited information about the utility of this technique in the clinical assessment

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9

Gray, Robert Donald. "Non-invasive biomarkers of inflammation in the assessment of cystic fibrosis lung disease." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/24641.

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Cystic fibrosis (CF) is the most common fatal inherited single gene defect in Caucasian populations. CF lung disease is characterised by infection, inflammation and progressive lung destruction. Lung inflammation is measurable in CF patients even with early disease. Gene therapy offers a theoretical cure for CF lung disease, with large clinical trials now being planned. There is not only a clear need for the development of new therapies in CF but also the means to measure the success of these therapies. One possible approach is to measure biomarkers of airway inflammation non-invasively (in sp

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10

Karlas, Thomas, and Johannes Wiegand. "Non-Invasive Assessment of Hepatic Steatosis in Patients with NAFLD Using Controlled Attenuation Parameter and 1H-MR Spectroscopy." Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-142654.

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Introduction: Non-invasive assessment of steatosis and fibrosis is of growing relevance in non-alcoholic fatty liver disease (NAFLD). 1H-Magnetic resonance spectroscopy (1H-MRS) and the ultrasound-based controlled attenuation parameter (CAP) correlate with biopsy proven steatosis, but have not been correlated with each other so far. We therefore performed a headto- head comparison between both methods. Methods: Fifty patients with biopsy-proven NAFLD and 15 healthy volunteers were evaluated with 1H-MRS and transient elastography (TE) including CAP. Steatosis was defined according to the percen

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11

Saynor, Zoe Louise. "Assessment and interpretation of aerobic exercise (dys)function in paediatric patients with cystic fibrosis." Thesis, University of Exeter, 2016. http://hdl.handle.net/10871/21875.

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The purpose of this thesis was to extend our understanding of the assessment and interpretation of aerobic exercise function of paediatric patients with cystic fibrosis (CF). The first investigation sought to establish (1) the validity of traditional criteria to verify maximal oxygen (V ̇O2max) during a maximal cardiopulmonary exercise test (CPET); and (2) the utility of supramaximal verification (Smax) to confirm V ̇O2max. Traditional criteria significantly underreported V ̇O2max, whilst Smax was shown to provide a valid measurement in this patient group. The reproducibility of this CPET prot

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12

Daniels, Thomas William Vaisey. "Longitudinal assessment of cystic fibrosis pulmonary disease using clinical, biochemical and emerging microbiological techniques." Thesis, University of Southampton, 2010. https://eprints.soton.ac.uk/196559/.

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Cystic Fibrosis (CF) causes chronic lower respiratory tract infection leading to morbidity and mortality. CF Pulmonary Exacerbations (CFPEs) cause accentuated symptoms and increase mortality. The definition and aetiology of CFPEs has however proved elusive. Recently, culture independent techniques have shown that there is much greater diversity of bacteria than previously detected by culture dependent methods. Building on this, in the work presented here, the bacteria in respiratory samples from adults with CF were studied over a 12 month period. Each subject provided thrice weekly sputum samp

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13

Zhao, Zhou. "Heart Segmentation and Evaluation of Fibrosis." Electronic Thesis or Diss., Sorbonne université, 2023. http://www.theses.fr/2023SORUS003.

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La fibrillation auriculaire est la maladie du rythme cardiaque la plus courante. En raison d'un manque de compréhension des structures atriales sous-jacentes, les traitements actuels ne sont toujours pas satisfaisants. Récemment, avec la popularité de l'apprentissage profond, de nombreuses méthodes de segmentation basées sur l'apprentissage profond ont été proposées pour analyser les structures auriculaires, en particulier à partir de l'imagerie par résonance magnétique renforcée au gadolinium tardif. Cependant, deux problèmes subsistent : 1) les résultats de la segmentation incluent le fond d

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Srivastava, Shelley. "Association of breath glucose with pulmonary disease in cystic fibrosis : assessment of a potential new biomarker." Thesis, St George's, University of London, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.568718.

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Introduction. Cystic fibrosis (CF) is the most common fatal genetic disease in the Western world. Fifty years ago, most sufferers died before their first birthday. With improved medical care, survival has now increased to adulthood. Respiratory failure, due to recurrent pulmonary exacerbations, is the main cause of mortality and morbidity. To enable clinical trials of new therapies, biomarkers of pulmonary disease are required. Traditionally, spirometry is used, but this is no longer sensitive enough. The development of chronic hyperglycaemia in CF is associated with accelerated pulmonary decl

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15

Mitchelmore, Philip. "Assessment of Pseudomonas aeruginosa epidemiology and the wider microbial diversity within the bronchiectatic lung." Thesis, University of Exeter, 2018. http://hdl.handle.net/10871/33665.

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The bronchiectatic lung is a diseased state in which the airways are chronically damaged and dilated. This state is found in the clinical entities of cystic fibrosis and non-cystic fibrosis bronchiectasis. These are two highly relevant chronic suppurative lung diseases in which an understanding of the microbiology of these patients is considered key to appropriate management. This has traditionally been via the use of traditional culture techniques. However, with the development of molecular methodologies, the previously perceived wisdom is being challenged. In both cystic fibrosis and non-cys

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16

Chin, Calvin Woon Loong. "Assessment and risk prediction in patients with aortic stenosis : insights from cardiovascular magnetic resonance." Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/15841.

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BACKGROUND Aortic stenosis affects not only the valve but also the myocardium. In response to the increased afterload, left ventricular hypertrophy initially occurs as a compensatory response to maintain wall stress and cardiac output but ultimately, decompensation and heart failure ensues. The transition from adaptation to decompensation is driven by myocyte death and myocardial fibrosis. The aims of the thesis are to investigate cardiovascular magnetic resonance assessment of disease severity and myocardial fibrosis, and explore its relationship with other biomarkers of disease activity and

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17

Horsley, Alex. "Non-invasive assessment of ventilation maldistribution in lung disease using multiple breath inert gas washouts." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/4512.

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Clinical research in cystic fibrosis (CF) requires study endpoints that are sensitive to airways disease, repeatable and non-invasive. Despite significant advances in the treatment of CF, lung function assessments continue to rely on the forced expiratory volume in 1 second (FEV1). Although simple to perform, it lacks sensitivity, is difficult for younger subjects, and changes over time. An alternative method of assessing lung physiology is to derive measures of ventilation heterogeneity from inert gas washout tests. In early lung disease, measures of gas mixing appear to be more sensitive tha

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18

Norén, Bengt. "Non-Invasive Assessment of Liver Fibrosis with 31P-Magnetic Resonance Spectroscopy and Dynamic Contrast Enhanced Magnetic Resonance Imaging." Doctoral thesis, Linköpings universitet, Medicinsk radiologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-90154.

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The present study aims at demonstrating phosphorus metabolite concentration changes and alterations in uptake/excretion of a hepatocyte specific contrast agent in patients with diffuse - or suspected diffuse - liver disease by applying two non-invasive quantitative MR techniques and to compare the results with histo-pathological findings, with focus on liver fibrosis. In the first study phosphorus-31 MR spectroscopy using slice selection (DRESS) was implemented. Patients with histopathologically proven diffuse liver disease (n = 9) and healthy individuals (n = 12) were examined. The patients h

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Singh, Harnoor. "YKL-40 as a non-invasive serum marker in assessment of rapid fibrosis progression post-orthotopic liver transplantation." Thesis, Boston University, 2012. https://hdl.handle.net/2144/12629.

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Thesis (M.A.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>Liver biopsy has been considered the gold standard method to assess the progression of fibrosis in chronic hepatitis C viral infection. Despite its prevalent use, significant complications along with patient dis

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Patel, Keyur. "Development of Serum Markers for the Non-Invasive Assessment of Longitudinal Change and Adjacent Stage Differentiation in Hepatic Fibrosis." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/16619.

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Development of Serum Markers for the Non-Invasive Assessment of Longitudinal Change and Adjacent Stage Differentiation in Hepatic Fibrosis Fibrogenesis is a dynamic process involving extracellular matrix synthesis and degradation that is dependent upon disease specific liver injury. The accepted standard measurement of hepatic fibrosis is through liver biopsy. Non-invasive markers of fibrosis were mostly developed in cross-sectional chronic hepatitis C (CHC) study cohorts. There is a need to develop valid non-invasive biomarkers of fibrosis that can follow dynamic changes in fibrogenesis. Our

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Barbosa, Claudia Regina 1974. "Perfil de micronutrientes em pacientes com fibrose cística acompanhados no HC da Unicamp." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/308360.

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Orientador: Antonio Fernando Ribeiro<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-21T12:18:48Z (GMT). No. of bitstreams: 1 Barbosa_ClaudiaRegina_D.pdf: 7431898 bytes, checksum: a7f4b9cfa0bef5d6df8cf4d0379cd809 (MD5) Previous issue date: 2012<br>Resumo: A Fibrose Cística (FC) é a doença de maior prevalência dentre as doenças hereditárias incidentes nos indivíduos caucasóides. A doença é progressiva e apresenta como manifestação clínica à obstrução respiratória crônica, infertilidade masculina e deficiência de gan

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McDonald, Catherine M. "Nutrition Education for Parents of Children with Cystic Fibrosis : Assessment of Needs and Strategies for Improved Knowledge and Confidence in Self Care." DigitalCommons@USU, 2005. https://digitalcommons.usu.edu/etd/5524.

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Suboptimal growth and nutritional status are problematic for children with cystic fibrosis (CF). Optimal nutrition predicts better lung function and longevity. Daily nutrition therapy for children with CF requires adequate food resources, knowledge of appropriate nutrition and behavior management skills, and confidence in one's ability to correctly apply the necessary skills. The Mountain West Cystic Fibrosis Consortium Questionnaire (MWCFC-Q) was designed as an educational needs assessment for parents of children with CF. The goal was to identify areas of concern that could be targeted for ed

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Aquino, Carlos Valentim Magalhães Nascimento Guarilha de. "Associação do estado nutricional com perfil inflamatório e a prática do exercício físico de crianças e adolescentes com fibrose cística." Instituto Fernandes Figueira, 2013. https://www.arca.fiocruz.br/handle/icict/8264.

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Made available in DSpace on 2014-08-26T17:31:44Z (GMT). No. of bitstreams: 2 license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) 69577.pdf: 1300093 bytes, checksum: c7113316350bfbf1edebdf53c7e1f74c (MD5)<br>Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Departamento de Ensino. Programa de Pós-Graduação em Saúde da Criança e da Mulher. Rio de Janeiro, RJ, Brasil.<br>O estado nutricional (EN) é marcador de prognóstico para pacientes com Fibrose Cística (FC) . O objetivo deste trabalho foi avaliar a associação do EN com o perfil inflamatório, prática de ati

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Pham, Hoang Minh [Verfasser]. "Cardiovascular Magnetic Resonance Imaging in the Assessment of Myocardial Blood Flow, Viability, and Diffuse Fibrosis in Congenital and Acquired Heart Disease / Hoang Minh Pham." Kiel : Universitätsbibliothek Kiel, 2014. http://d-nb.info/1052893724/34.

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25

Axelsson, Therese. "An assessment of patients followed for Hepatitis B at the Department of Infectious Diseases at Örebro University Hospital : - Factors associated with significant liver fibrosis evaluated by transient elastography." Thesis, Örebro universitet, Institutionen för medicinska vetenskaper, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-76215.

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Introduction: Chronic hepatitis B (CHB) is a viral infection that can lead to development of fibrosis and hepatocellular carcinoma (HCC). Several factors affecting disease progression have been reported, such as sex and region of origin. Liver stiffness and fibrosis can be evaluated using transient elastography. The degree of fibrosis is an important parameter when deciding if treatment and HCC surveillance is indicated. Aim1) To compare patients with CHB according to sex and region of origin regarding the parameters liver stiffness, presence of significant fibrosis, hepatitis B e antigen (HBe

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Stark-Kent, Dorothea [Verfasser]. "Evaluation of 13C Mixed Triglyceride Breath Testing and Fecal Elastase 1 assays for the assessment of pancreatic function in babies with cystic fibrosis : Including an assessment of healthy babies to establish the range of normal for the 13C Breath test / Dorothea Stark-Kent." Bonn : Universitäts- und Landesbibliothek Bonn, 2019. http://d-nb.info/1182042996/34.

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27

Williams, J. E. "A longitudinal study of the body composition of children with cystic fibrosis compared to healthy children using the four-component model with an assessment of clinical tools available for body composition measurements." Thesis, University College London (University of London), 2013. http://discovery.ucl.ac.uk/1402787/.

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Body composition (BC) is an important prognostic factor in patients with cystic fibrosis (CF). International guidelines recommend monitoring growth and nutritional status in children with CF using simple anthropometry. However, methodological issues with simple techniques are more significant in children due to growth and maturation, and even more problematic in patients, perhaps accounting for inconsistent findings in previous BC research in children with CF. My thesis addressed three aims: 1) comparison of BC in young children with CF and controls using the criterion four-component model (4C

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Sharma, Sanjay. "On the improvement of permeability assessment of fibrous materials." Diss., Wichita State University, 2010. http://hdl.handle.net/10057/3288.

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The focus of this work is to understand the current state of permeability measurement and prediction methods for fibrous, porous media and to suggest improvements. For this purpose the most widely used and accepted measurement technique, the channel flow method, is used to experimentally investigate the effects of fiber sizing and fluid viscosity on the permeability of glass and carbon fibers. Experiments have shown that the variation in permeability occurs due primarily to the fluid viscosity and not the nature of fluid, which other researchers have proposed. Studies were also carried out on

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Castro, Rejane Agnelo Silva de. "Validade e reprodutibilidade do COPD assessment test (CAT) em pacientes com bronquiectasia não-fibrose cística." Universidade Nove de Julho, 2015. http://bibliotecatede.uninove.br/handle/tede/1817.

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Submitted by Nadir Basilio (nadirsb@uninove.br) on 2018-06-19T18:12:45Z No. of bitstreams: 1 Rejane Agnelo Silva de Castro.pdf: 1052641 bytes, checksum: 1f8691a5b4f1dcb3d43ec9c6aa9e4345 (MD5)<br>Made available in DSpace on 2018-06-19T18:12:45Z (GMT). No. of bitstreams: 1 Rejane Agnelo Silva de Castro.pdf: 1052641 bytes, checksum: 1f8691a5b4f1dcb3d43ec9c6aa9e4345 (MD5) Previous issue date: 2015-11-27<br>Introduction: Instruments to objectively assess the perception of symptoms in patients with BCQ are scarce. Patients with COPD and bronchiectasis (BCQ) share similar symptoms. Therefore, COPD

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Branley, Howard Matthew. "Non-invasive assessment of macrophage behaviour and pulmonary inflammation in fibrosing alveolitis due to systemic sclerosis." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501207.

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Silva, Adikarige Ayona Therese Nilmini. "Assessment and control of conditions in the rumen to increase utilization of fibrous roughages in ruminants." Thesis, University of Aberdeen, 1985. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU363238.

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CHAPTER 2 Five experiments were conducted to investigate the dietary factors within the rumen environment which could contribute to the rate of degradation of straw. Three sources of digestible cellulose and/or hemicellulose (unmolassed sugar beet pulp, citrus pulp and dried grass) and two sources of natural proteins (fish meal and soya bean meal) were investigated for their ability to increase degradation of straw In. sacco in sheep, as supplements to untreated straw. The untreated straw used in these experiments was adequately supplemented with rumen degradable nitrogen, sulphur, vitamins an

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Pott, Julian [Verfasser]. "Etablierung des „COPD Assessment Test“ zur Erfassung der Lebensqualität bei Patienten mit Cystischer Fibrose : Ein Vergleich zwischen Fragebögen und klinischen Parametern / Julian Pott." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2020. http://d-nb.info/122833367X/34.

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Ikonen, Linus, and Daniel Nilsson. "Quality assessment of mineral wool insulation plates : Using ultrasonic non-destructive testing." Thesis, Blekinge Tekniska Högskola, Institutionen för maskinteknik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-18223.

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In the manufacturing process of mineral wool insulation plates, defects arise, such as unmelted base minerals and uncured binder which gets embedded within the plates. To be able to sort out these defective plates from a manufacturing line, a reliable quality assessment is needed. The aim is to find an ultrasonic non-destructive testing method that can identify the embedded defects. This was achieved through experiments on defective insulation plates using three different ultrasonic non-destructive testing methods that were of interest. These methods were higher harmonics, pulse-echo and throu

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Lee, Lin Hu, and 胡李琳. "Quantitative Assessment for Skeletal Muscle Fibrosis." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/63986662763214629094.

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碩士<br>臺灣大學<br>應用力學研究所<br>98<br>Congenital muscular torticollis ( CMT ) caused by the fibrotic change of the sternocleidomastoid muscle ( SCM ) can be detected by ultrasonography. The incidence of CMT varies from 0.3% to 2% in literature and is the third skeletal muscular diseases in infants. This study aimed to combine the advantages of ultrasound and the accuracy of histopathology to construct objective diagnostic reference by animal model. We proposed a K value based on the ultrasound image’s difference of mean echo intensity in injured and normal side, and K value has positive correlation w

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Chuang, Sheng-Hsiang, and 莊勝翔. "Liver Fibrosis Assessment Using Ultrasound Backscattering Dynamics Statistical Parametric Imaging Index." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/41503826089982389602.

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碩士<br>國立臺灣大學<br>應用力學研究所<br>99<br>This study is dedicated to the application of liver fibrosis assessment using ultrasound imaging, focusing on the envelope signal converted from RF signal to investigate the differences of the statistical distributions between healthy and disease livers. Liver cirrhosis is considered as an irreversible process that there is almost no effective course of treatment to recover the fibrosis liver. Fibrosis is marked by the gradual replacement of hepatocytes by extracellular collagen, which is a chronic and long-term degeneration of the liver function. Invasive asse

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Hsu, Hsuan-Che, and 徐宣哲. "The efficacy assessment of oral adsorbent ameliorated liver fibrosis-induced abnormalities in rats." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/67152216885273820082.

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Bo-YenHuang and 黃柏諺. "In vivo Quantitative Assessment of Hepatic Fibrosis by Ultrasonic Backscattering and Statistical Model." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/4gzb8b.

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碩士<br>國立成功大學<br>資訊工程學系<br>105<br>In general, the liver biopsy is the most accurate method to assess liver fibrosis. The liver biopsy is a procedure to remove a small piece from liver tissue and it is invasive that can cause many complications. Besides, rats are widely used in liver fibrosis experiments and a lot of rats are sacrificed to verify, assess the liver fibrosis level and reduced the sampling errors. Therefore, ultrasound and statistical parameters were used to assess the liver fibrosis as a non-invasive method in this study. Sprague Dawley rats were induced liver fibrosis by CCl4. A

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Vinco, Giulia. "Assessment of Myocardial Fibrosis Using Advanced Echocardiography in Patients With Systemic Lupus Erythematosus: a Pilot Study." Doctoral thesis, 2021. http://hdl.handle.net/11562/1049393.

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Background: Systemic lupus erythematosus (SLE) is an autoimmune disease, which is characterized by a multi-organ involvement and increased mortality, mainly due to cardiovascular complications. Myocardial fibrosis (MF) is common in SLE, affecting up to 30% of these patients. Cardiac magnetic resonance imaging allows an accurate assessment of myocardial tissue in SLE patients, but it is costly, time consuming, and unfit for patients with coexisting chronic kidney disease. Recent advanced echocardiographic techniques allow an accurate assessment of MF. In particular, speckle tracking echocardiog

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Chang, Chin-Chen, and 張晉誠. "Functional Imaging of the Liver: Gd-EOB-DTPA-enhanced MRI for Assessment of Hepatic Function and Fibrosis." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/9n9x3n.

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博士<br>國立陽明大學<br>生物醫學影像暨放射科學系<br>107<br>Abstract Chronic liver disease usually accompanies parenchymal fibrosis and hepatic dysfunction. The consequences also affect prognosis and treatment outcome. Tissue proof is considered as gold standard to monitor the disease progression; however, repeated procedure is not practicable due to its invasiveness and possible complications. Non-invasive methods for assessing liver function and parenchymal fibrosis have been developed. Gd-EOB-DTPA is a liver-specific MR contrast agent, which can provide anatomical and functional information for imaging diagnosi

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Theng, Si Min, and 鄧思敏. "Assessment of the Therapeutic Efficacy of Oncostatin M-preconditioned MSCs in the Bleomycin-induced Pulmonary Fibrosis Mouse Model." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/40288781243802172489.

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碩士<br>長庚大學<br>醫學生物技術暨檢驗學系<br>100<br>Idiopathic pulmonary fibrosis (IPF) is characterized by an intricate cytokine network and abnormal deposition of mesenchymal cells. Recent studies indicated that Oncostatin M (OSM), a member of IL-6 family cytokine, was up-regulated in the bronchoalveolar lavage fluid (BALF) of patients with interstitial lung disease. Furthermore, exogenous administration of OSM into the lungs of mice resulted in a significant recruitment of inflammatory cells, as well as a dose-dependent increase of collagen deposition in the lungs. These results suggested that OSM is a pot

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Maglione, Marco. "Towards a global assessment of pediatric non-cystic fibrosis chronic pulmonary disorders: new insights in disease diagnosis and monitoring." Tesi di dottorato, 2017. http://www.fedoa.unina.it/11470/7/maglione_marco_29.pdf.

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Classification of chronic lung disease (CLD) in children has traditionally distinguished cystic fibrosis (CF), the most common lethal inherited genetic disorder worldwide, from less common non-CF disorders, a heterogeneous group of conditions with different etiologies, but overlapping clinical features. While in CF the multi-organ involvement has traditionally required a systemic approach to patients’ care, not limited to respiratory issues, in non-CF CLD this aspect has often been neglected. However, an increasing awareness is emerging regarding the need to adequately address issues such as g

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Zhuang, Shu-Ru, and 莊淑如. "Studies on the life style, diet behavior, nutrition assessment and immune function of patients with oral submucous fibrosis or oral cancer." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/56093316956965963394.

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碩士<br>中山醫學院<br>營養科學研究所<br>88<br>Abstract Oral submucous fibrosis (OSF), an obscure oral pathosis, is characterized by an abnormal accumulation of oral submucous collagen fibers, epithelium atrophy, and the resultant limitation of mouth opening. Studies indicated that OSF was one of precarcinogenic lesions and mortality of oral cancer is the fifth cause of cancer-related death among men. The reasons for the occurrence of OSF and oral cancer were still unknown. Some studies showed that it is closely related to nutritional deficiency, but it is limited to the related evidence. The purp

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Fakuade, Funsho Emmanuel. "An integrative and translational assessment of altered atrial electrophysiology, calcium handling and contractility in patients with atrial fibrillation." Doctoral thesis, 2020. http://hdl.handle.net/21.11130/00-1735-0000-0005-14F1-4.

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SAFFIOTI, FRANCESCA. "Non-invasive assessment of liver fibrosis and portal hypertension in primary sclerosing cholangitis and primary biliary cholangitis: transient elastography, point share wave elastography and biomarkers." Doctoral thesis, 2018. http://hdl.handle.net/11570/3146302.

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Background and Aims: There is an ongoing effort to identify non-invasive surrogates for staging liver disease and detecting clinically significant portal hypertension (CSPH), defined as the presence of gastro-oesophageal varices on endoscopy. Transient elastography performed by Fibroscan (F-TE) has a well-established role in the non-invasive assessment of liver fibrosis and is widely used in clinical practice. Point Share Wave Elastography (pSWE) is a new software-based technique that measures liver stiffness during B-mode ultrasonography. Data about its performance in primary cholestatic li

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Silva, Joana Sílvia Delgado. "Safety and efficacy of catheter-based renal denervation for the management of resistant hypertension: clinical, imaging and immunological assessment." Doctoral thesis, 2022. http://hdl.handle.net/10316/98609.

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Tese de Doutoramento em Ciências da Saúde, Medicina, apresentada à Faculdade de Medicina da Universidade de Coimbra.<br>Hypertension (HT) is the most common modifiable cardiovascular risk factor and is responsible for significant mortality and morbidity. It is estimated that 30-45% of the adult population has HT, with its prevalence increasing with advancing age. The employment of lifestyle changes and drug therapy reduces the risk of major cardiovascular events such as acute myocardial infarction, stroke and heart failure and increases life-expectancy. However, despite the availability of saf

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Agrawalla, Abhisek, and Namrata Keshri. "Durability Assessment of Multiwalled Carbon-Nanotubes Modified Advanced Fibrous Polymeric Composite in Different Marine Environment." Thesis, 2015. http://ethesis.nitrkl.ac.in/6799/1/DURABILITY_Agrawalla_2015.pdf.

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Fibre reinforced polymer (FRP) composite is one of the most promising material system of 21st century due to high strength to weight ratio, non-corrosive nature, flexibility and easy fabrication. FRP has enormous demand for application in diversified fields like aerospace, submarines, underwater pipeline, automobiles, architectural components, satellites etc. Major dilemma is faced by researchers, when FRP composites are exposed to harsh and hostile environments. FRP composites are prone to degradation when exposed to humid environments, cryogenic environments,high temperature, different radia

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Oduneye, Samuel. "MR-Guided Assessment and Management of Ventricular Tachycardia." Thesis, 2013. http://hdl.handle.net/1807/43685.

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This thesis describes the electrical and physiological characterization of cardiac tissue with myocardial infarction (MI) responsible for abnormal cardiac rhythms such as ventricular tachycardia (VT), using a newly-developed magnetic resonance imaging (MRI) electrophysiology system. In electrophysiology (EP), radiofrequency (RF) catheter ablation combined with cardioverter-defibrillator implantation is a first-line action to manage ventricular VT. Unfortunately, this therapy is known to have sub-optimal success rates in a large number of patients because of difficulties to accurately identifyi

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Dalai, Renu Prava. "An Assessment of Mechanical Behavior of Fibrous Polymeric Composites Under Different Loading Speeds at Above- And Sub-Ambient Temperatures." Thesis, 2010. http://ethesis.nitrkl.ac.in/2049/1/thesis_renu.pdf.

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Advanced fibrous polymeric composites are one of the most successful composite material systems due to its wide range of advantages such as high specific strength and stiffness, fatigue properties and corrosion resistance. Composite structures undergo different loading conditions i.e. from static to dynamic during their service life. During a cruise cycle an aircraft structure undergo different temperatures starting from ambient temperature on ground to during flight at 30,000 ft (-50˚C) and +50˚C during stays at the tropic and arid places. The polymer matrix is more susceptible to these chang

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