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1

Feyereisen, Gary W., Ehsan Ghane, Todd W. Schumacher, Brent J. Dalzell, and M. R. Williams. "Can Woodchip Bioreactors Be Used at a Catchment Scale? Nitrate Performance and Sediment Considerations." Journal of the ASABE 66, no. 2 (2023): 367–79. http://dx.doi.org/10.13031/ja.15496.

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Highlights Novel three-bed, cascading-inlet bioreactor treated agricultural drainage from a 249-ha catchment. Nitrate removal rates and load reduction efficiencies were similar to those of traditional single-field bioreactors. Sedimentation problems reduced bed life; a sediment sensing and exclusion system solved them. This scale provides opportunities for centralized management and nutrient reduction verification. Abstract. Denitrifying bioreactors, a structural practice deployed at the field scale to meet water quality goals, have been underutilized and require additional evaluation at the s
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Hartfiel, Lindsey M., Michelle L. Soupir, and Kurt A. Rosentrater. "Techno-Economic Analysis of Constant-Flow Woodchip Bioreactors." Transactions of the ASABE 64, no. 5 (2021): 1545–54. http://dx.doi.org/10.13031/trans.14300.

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HighlightsTechno-economic analysis was performed for multiple scales of bioreactors operated under a variety of conditions.The unit cost decreased as the bioreactor size increased.The unit cost increased in bioreactors with longer HRTs and bypass flow due to reduced treatment capacity.One large bioreactor was more cost-effective than multiple smaller bioreactors.Abstract. Woodchip denitrification bioreactors are a relatively new, edge-of-field technology used to reduce nitrate-nitrogen (NO3-N) from subsurface tile drainage. The removal rate of nitrate is influenced by many factors, including t
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Jeyakumar, Lordwin Girish Kumar, David B. McKenzie, Laura E. Christianson, and Evan Derdall. "Initial Validation of a Replicated Field-scale Denitrifying Bioreactor Facility in a Boreal Environment." Advances in Environmental and Engineering Research 02, no. 02 (2020): 1. http://dx.doi.org/10.21926/aeer.2102005.

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Denitrifying bioreactor technology, where a solid carbon source (woodchips) acts as a reactive medium to intercept agricultural tile drainage water, has been successfully used to convert N (NO3-) to di-nitrogen (N2) gas. Four replicated field-scale (24 m long x 3 m wide x 1 m deep), bioreactors were built and operated at the St. John’s Research and Development Centre and were successful at removing a notable amount of nitrate (N) from agricultural subsurface drainage water. The objective of this study was to investigate the internal flow dynamics of one of these field-scale bioreactors as a pr
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Malhotra, Neeraj. "Bioreactors Design, Types, Influencing Factors and Potential Application in Dentistry. A Literature Review." Current Stem Cell Research & Therapy 14, no. 4 (2019): 351–66. http://dx.doi.org/10.2174/1574888x14666190111105504.

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Objectives:A variety of bioreactors and related approaches have been applied to dental tissues as their use has become more essential in the field of regenerative dentistry and dental tissue engineering. The review discusses the various types of bioreactors and their potential application in dentistry.Methods:Review of the literature was conducted using keywords (and MeSH) like Bioreactor, Regenerative Dentistry, Fourth Factor, Stem Cells, etc., from the journals published in English. All the searched abstracts, published in indexed journals were read and reviewed to further refine the list of
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5

Wickramarathne, Niranga M., Richard A. Cooke, Ruth Book, and Laura E. Christianson. "Denitrifying Woodchip Bioreactor Leachate Tannic Acid and True Color: Lab and Field Studies." Transactions of the ASABE 63, no. 6 (2020): 1747–57. http://dx.doi.org/10.13031/trans.14020.

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HighlightsOak leached more tannic acid, true color, and chemical oxygen demand (COD) than ash and mixed hardwood chips.The factors became similar (tannic acid, COD) or below stream levels (true color) after flushing.Eleven site-years of field bioreactor data showed decreasing tannic acid and true color over time.Post-startup tannic acid was lower in bioreactor outflow than in area streams.True color did not appear to be a reliable indicator of leachate tannic acid at low concentrations.Abstract. Woodchips have been a preferred denitrifying bioreactor medium to date, but concerns about potentia
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JOVANOVIĆ, Sofija, Ivan BOŽIĆ, Biljana STOJANOVIĆ, Branislava LEKIĆ, and Nikola KILIBARDA. "NUMERIČKA SIMULACIJA I OPTIMIZACIJA STRUJANJA FLUIDA U BIOREAKTORU POSTROJENJA ZA PREČIŠĆAVANJE OTPADNIH VODA." Vodoprivreda 56, no. 1-2 (2024): 17–26. https://doi.org/10.46793/vodoprivreda56.1-2.17j.

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In bioreactors of wastewater treatment plants, biological processes based upon an adequate fluid flow are taking place. In order to achieve as effective as possible operation of a bioreactor, of utmost importance are knowledge and analysis of the flow field in it, determination of unfavorable flow zones, as well as the establishment of the corresponding designs for improvement of flow field and general improvement of water treatment. In present paper an analysis of a flow field in the bioreactor of the specific wastewater treatment plant (WWTP) in Republic of Serbia was performed by means of c
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Zablodskiy, M., P. Klendiy, O. Dudar, and I. Radko. "Research of the Influence of the Combined Electromagnetic Field on Biogas Output." Problems of the Regional Energetics, no. 2(58) (May 2023): 81–96. http://dx.doi.org/10.52254/1857-0070.2023.2-58-08.

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The purpose of research is determining the conditions of stimulating effect of the combined influence of constant and variable electromagnetic fields on the substrate and microorganisms in the bioreactor. This goal is achieved by solving the following tasks: development of mathematical model, conducting numerical simulation to determine the distribution of magnetic field in active zones of the stator-bioreactor system; conducting experimental researches during the fermentation of pig’s manure with litter from wheat straw in the mesophilic mode of fermentation. One category of bioreactors (cont
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Sassi, Lisa, Omolola Ajayi, Sara Campinoti, et al. "A Perfusion Bioreactor for Longitudinal Monitoring of Bioengineered Liver Constructs." Nanomaterials 11, no. 2 (2021): 275. http://dx.doi.org/10.3390/nano11020275.

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In the field of in vitro liver disease models, decellularised organ scaffolds maintain the original biomechanical and biological properties of the extracellular matrix and are established supports for in vitro cell culture. However, tissue engineering approaches based on whole organ decellularized scaffolds are hampered by the scarcity of appropriate bioreactors that provide controlled 3D culture conditions. Novel specific bioreactors are needed to support long-term culture of bioengineered constructs allowing non-invasive longitudinal monitoring. Here, we designed and validated a specific bio
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9

Kuyukina, Maria S., Anastasiya V. Krivoruchko, and Irena B. Ivshina. "Advanced Bioreactor Treatments of Hydrocarbon-Containing Wastewater." Applied Sciences 10, no. 3 (2020): 831. http://dx.doi.org/10.3390/app10030831.

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This review discusses bioreactor-based methods for industrial hydrocarbon-containing wastewater treatment using different (e.g., stirred-tank, membrane, packed-bed and fluidized-bed) constructions. Aerobic, anaerobic and hybrid bioreactors are becoming increasingly popular in the field of oily wastewater treatment, while high concentrations of petroleum hydrocarbons usually require physico-chemical pre-treatments. Most efficient bioreactor techniques employ immobilized cultures of hydrocarbon-oxidizing microorganisms, either defined consortia or mixed natural populations. Some advantages of fl
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10

Grün, Christoph, Brigitte Altmann, and Eric Gottwald. "Advanced 3D Cell Culture Techniques in Micro-Bioreactors, Part I: A Systematic Analysis of the Literature Published between 2000 and 2020." Processes 8, no. 12 (2020): 1656. http://dx.doi.org/10.3390/pr8121656.

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Bioreactors have proven useful for a vast amount of applications. Besides classical large-scale bioreactors and fermenters for prokaryotic and eukaryotic organisms, micro-bioreactors, as specialized bioreactor systems, have become an invaluable tool for mammalian 3D cell cultures. In this systematic review we analyze the literature in the field of eukaryotic 3D cell culture in micro-bioreactors within the last 20 years. For this, we define complexity levels with regard to the cellular 3D microenvironment concerning cell–matrix-contact, cell–cell-contact and the number of different cell types p
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11

Christianson, Laura Elizabeth, Reid Christianson, Carolina Díaz-García, et al. "Denitrifying Bioreactor In Situ Woodchip Bulk Density." Journal of the ASABE 66, no. 3 (2023): 723–34. http://dx.doi.org/10.13031/ja.15364.

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Highlights The bulk density of woodchips in denitrifying bioreactors in the field is unknown. In situ bulk density estimation methods were developed for use during construction or excavation. Dry bulk densities of aged woodchips at bioreactor bottoms were lower than previous literature values. Moisture and particle size and density explained some, but not all, of the variation in in situ bulk densities. Abstract. Woodchip bulk density in a denitrifying bioreactor governs system hydraulics, but this prime physical attribute has never been estimated in situ. The objectives were twofold: (1) to e
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12

Gosch, Lennart, Haojie Liu, and Bernd Lennartz. "Performance of a Woodchip Bioreactor for the Treatment of Nitrate-Laden Agricultural Drainage Water in Northeastern Germany." Environments 7, no. 9 (2020): 71. http://dx.doi.org/10.3390/environments7090071.

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Reactive barriers, such as denitrifying bioreactors, have been identified as a clean-up option for nutrient-laden agriculture runoff. Here we tested a 20 m long, 3.75 m wide and 2.2 m deep woodchip bioreactor receiving tile drainage water from a 5.2 ha field site, aiming at testing the hydraulic functioning of a dual-inlet system and quantifying its impact on nutrient loads (nitrogen, reactive phosphorus, organic carbon) in a region with a drainage season taking place in the hydrological winter (November to April). The hydraulic conditions in the dual-inlet bioreactor system developed differen
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13

Feyereisen, Gary W., Christopher Hay, Ulrike W. Tschirner, et al. "Denitrifying Bioreactor Woodchip Recharge: Media Properties after Nine Years." Transactions of the ASABE 63, no. 2 (2020): 407–16. http://dx.doi.org/10.13031/trans.13709.

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HighlightsWood media harvested from a nine-year-old denitrifying bioreactor were evaluated.Media physical changes had multiple causes and effects.Impacts of the physical changes may have been exacerbated by development of preferential flow.LCIs > 0.6 showed C quality declined but media still supported N removal.Abstract. There is a lack of information on denitrifying bioreactors treating subsurface drainage water at the end of their initial design life due to the relative newness of the technology and the relatively long estimated life. A denitrifying bioreactor (15 m L × 7.6 m W × 1.1
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14

Qiao, Bo Bo, Rui Tian, Chun Li Li, Rui Fang Li, Xue Qing Dong, and Jia Long Wen. "Study on the Flow Field in Membrane Bioreactor Research by Using PIV." Advanced Materials Research 516-517 (May 2012): 1078–81. http://dx.doi.org/10.4028/www.scientific.net/amr.516-517.1078.

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Membrane bioreactor flow field distribution directly affect effective control of the membrane pollution,and affect the membrane flux greatly. The experiments of membrane bioreactor liquid are measured by using PIV that the measurement areas include membrane bioreactor upper, middle and lower. The experimental data obtained velocity field information through the PIV software analysis. The experimental result indicates that middle of the membrane bioreactor flow field is the most unstable. The experimental measurement result provide membrane bioreactor structure the optimized design, effective c
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15

Debnath, Samir C. "Developing a scale-up system for the in vitro multiplication of thidiazuron-induced strawberry shoots using a bioreactor." Canadian Journal of Plant Science 88, no. 4 (2008): 737–46. http://dx.doi.org/10.4141/cjps07147.

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The use of large-scale liquid cultures in a bioreactor system has the potential to resolve the manual handling of the various stages of micropropagation and increases shoot multiplication in vitro significantly compared with those cultured on semi-solid gelled medium. In an attempt to improve the micropropagation protocol for strawberry (Fragaria × ananassa Duch.), a procedure for the mass propagation of adventitious shoots regenerated from leaf, sepal and petiole explants of cultivar Bounty using a liquid medium-containing bioreactor system combined with gelled medium is described. Leaf disks
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16

Nečiporenko, Anatolij, Feliksas Ivanauskas, Jurgita Dabulytė-Bagdonavičienė, Arvydas Povilaitis, and Valdas Laurinavičius. "NITRATE REMOVAL IN WOODCHIP DENITRIFICATION BIOREACTOR – AN APPROACH COMBINING MATHEMATICAL MODELLING AND PI CONTROL." Journal of Environmental Engineering and Landscape Management 30, no. 1 (2022): 13–21. http://dx.doi.org/10.3846/jeelm.2022.15295.

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A mathematical model of nitrate removal in woodchip denitrification bioreactor based on field experiment measurements was developed in this study. The approach of solving inverse problem for nonlinear system of differential convection-reaction equations was applied to optimize the efficiency of nitrate removal depending on bioreactor’s length and flow rate. The approach was realized through the developed algorithm containing a nonlocal condition with an incorporated PI controller. This allowed to adjust flow rate for varying inflow nitrate concentrations by using PI controller. The proposed mo
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17

Kordas, Marian, Maciej Konopacki, Bartłomiej Grygorcewicz, et al. "Hydrodynamics and Mass Transfer Analysis in BioFlow® Bioreactor Systems." Processes 8, no. 10 (2020): 1311. http://dx.doi.org/10.3390/pr8101311.

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Biotechnological processes involving the presence of microorganisms are realized by using various types of stirred tanks or laboratory-scale dual-impeller commercial bioreactor. Hydrodynamics and mass transfer rate are crucial parameters describing the functionality and efficiency of bioreactors. Both parameters strictly depend on mixing applied during bioprocesses conducted in bioreactors. Establishing optimum hydrodynamics conditions for the realized process with microorganisms maximizes the yield of desired products. Therefore, our main objective was to analyze and define the main operation
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18

Yu, Chi, Gang Wang, Jing Zhang, and Shi Ping Zhan. "Flow Field Numerical Simulation on the Membrane Aeration Biofilm Reactor." Advanced Materials Research 945-949 (June 2014): 1003–6. http://dx.doi.org/10.4028/www.scientific.net/amr.945-949.1003.

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Based on the design of membrane bioreactor three-dimensional finite element model is established,Finite volume method was applied to sewage treatment in the process of membrane bioreactor internal flow field is unsteady flow numerical simulation and analysis. The results of numerical simulation can be seen at the bottom of the membrane module speed change is small, to purify sewage full contact with membrane module, the upper change is bigger, treated sewage can be quickly exhaust to the outside world. This study on flow field of the bioreactor of in-depth study, the new structure design and o
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Sereda, Mikhail, Olga Kapralova, and Tatiana Varduni. "Use of rocker bioreactor for propagation of the Vaccinium corymbosum L." BIO Web of Conferences 130 (2024): 01027. http://dx.doi.org/10.1051/bioconf/202413001027.

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Plant biotechnology has the potential to meet the market demand for a significant number of seedlings. The current state of the industry is characterised by exemplary results in the field of micropropagation, with notable achievements observed in the cultivation of diverse plant crops, particularly berries. Nevertheless, certain aspects of this technology remain imperfect at the industrial level. The multiplication of microshoots of berry crops remains a costly process. The transition of numerous laboratories from semi-solid agar medium to liquid has resulted in a reduction in the costs associ
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20

Kostova, Jordanka, Sylvio Schneider, Sabine Sauer, Andrea Böhme, Mauro Casalboni, and Andreas H. Foitzik. "Novel Bioreactor-System for In Situ-Cultivation of Artificial Tissue." Materials Science Forum 879 (November 2016): 1002–7. http://dx.doi.org/10.4028/www.scientific.net/msf.879.1002.

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A bioreactor is a device simulating physiological environments for different biotechnological applications. In highly promising research fields like tissue engineering micro-sized bioreactors were utilized successfully promoting mammalian cells to grow and build 3D cell structures similar to in vivo environments. For any practical application and even for improved R&D it is necessary to generate and maintain a physiological environment over the whole cultivation period (hours, days or weeks, in case of artificial organs even up to months). Depending on the field of application physiologica
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Apazhev, A. K., B. A. Fiapshev, L. M. Khazhmetov, A. M. Egozhev, and A. G. Fiapshev. "MODELING OF THERMAL PROCESSES IN A BIOGAS INSTALLATION." Техника и технологии в животноводстве 15, no. 1 (2025): 77–82. https://doi.org/10.22314/27132064-2025-15-1-77.

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Disinfection of manure and the biogas through its anaerobic in bioreactors receiving is a promising direction at livestock waste’s rational use problem solving. The most promising manure processing system is biogas installation with thermophilic fermentation regime using. There are many biogas installations’ designs, from the simplest in the form of a plastic bag or a well with a floating hood till industrial ones with automatic biomass heating and biogas purificating. However, in principle, they all represent a chain of aggregates: a system for biomass (mixing it with water) preparing and the
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Warith, Mostafa. "Bioreactor landfills: experimental and field results." Waste Management 22, no. 1 (2002): 7–17. http://dx.doi.org/10.1016/s0956-053x(01)00014-9.

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Skała, Ewa, Monika A. Olszewska, and Agnieszka Kicel. "The Enhancement of Biomass Accumulation, Caffeoylquinic Acid Derivative Production, and Antioxidant Activity of Rhaponticum carthamoides Transformed Roots Cultured in a Nutrient Sprinkle Bioreactor." International Journal of Molecular Sciences 26, no. 4 (2025): 1422. https://doi.org/10.3390/ijms26041422.

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Rhaponticum carthamoides (Willd.) Iljin. is an endemic plant species found in Siberia, Mongolia, and Kazakhstan. Its roots and rhizomes are used to treat physical fatigue and weakness following illness. The present study examines the scaling up of caffeoylquinic acid (CQA) derivative and flavonoid production in R. carthamoides transformed roots. The transformed roots were grown in shaken Erlenmeyer flasks of varying volumes (0.5–2 L), a temporary immersion system (TIS) (Rita® and PlantForm bioreactors), and a nutrient sprinkle bioreactor (NSB) in Woody Plant medium for 35 days. The highest dry
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An, Yang, and Dong Li. "Engineering skeletal muscle tissue in bioreactor systems." Chinese Medical Journal 127, no. 23 (2014): 4130–39. http://dx.doi.org/10.3760/cma.j.issn.0366-6999.20141076.

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Objective To give a concise review of the current state of the art in tissue engineering (TE) related to skeletal muscle and kinds of bioreactor environment. Data sources The review was based on data obtained from the published articles and guidelines. Study selection A total of 106 articles were selected from several hundred original articles or reviews. The content of selected articles is in accordance with our purpose and the authors are authorized scientists in the study of engineered muscle tissue in bioreactor. Results Skeletal muscle TE is a promising interdisciplinary field which aims
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Xu, Shu. "Study on Temperature Field of L-Phenylalanine Fermentation in Heat Pipe Bioreactor." Advanced Materials Research 393-395 (November 2011): 984–87. http://dx.doi.org/10.4028/www.scientific.net/amr.393-395.984.

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L-phenylalanine fermentation (L-Phe) is produced by the preparation method of PPA-transamination using the ferment liquor, which is the production of the E.coli No.1 fermented in heat pipe bioreactor (HPBR), the technical indexes are superior. The temperature profile of ferment liquor in the period of microbe growth is well distributed, the mean difference in temperature is 0.08°C, while the maximum value is 0.4°C.Base on operational principle of heat pipe, HPBR solves many problems on heat transfer in traditional bioreactor: nonuniformity of temperature profile, inefficiency of heat transfer
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Penn, Chad, M. R. Williams, Manal Askar, Jedediah Stinner, and Kevin W. King. "Stack’em Up: Field-Scale Performance of a Stacked Woodchip Bioreactor and Phosphorus Removal Structure." Applied Engineering in Agriculture 40, no. 6 (2024): 715–28. https://doi.org/10.13031/aea.16145.

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HighlightsBioreactor removed 5% and 2% of nitrate-nitrogen (N) and dissolved P (DP), respectively, from total drainage with 93% bypass.P removal structure (PRS) handled all flow at 7 L s-1, thereby removing 30% and 29% of DP and nitrate-N from total drainage volume, respectively, despite low DP inflow concentrations.PRS removed 74% of DP during 9-d P inflow spike test, 3x greater load removal than 2-yr natural loads.Construct PRS at P critical source areas for max efficiency; design bioreactors and PRS for treating as much peak flow as possible.Abstract. The combination of nitrate and dissolve
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Zhu, Li Kuan, Bo Yan Song, Zhen Long Wang, and Yu Kui Wang. "Optimze the Structure of Impeller for Stirred Bioreactor." Advanced Materials Research 694-697 (May 2013): 148–53. http://dx.doi.org/10.4028/www.scientific.net/amr.694-697.148.

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This paper mainly makes comparative analysis on four main types of blade in stirred bioreactor by Computational Fluid Dynamics(CFD) simulation. Firstly we establish simulation method suited for stirred bioreactor, then simulate the velocity and shear force of flow field in the bioreactor. No matter from flow field mixing or shear force aspect, Elephant Ear blades is the most suitable for cell large scale culture. At last, it optimizes the installation method and angle of Elephant Ear blades. It concludes that anticlockwise rotation and 45°installation angle is the optimum.
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Bareither, Christopher A., Ronald J. Breitmeyer, Craig H. Benson, Morton A. Barlaz, and Tuncer B. Edil. "Deer Track Bioreactor Experiment: Field-Scale Evaluation of Municipal Solid Waste Bioreactor Performance." Journal of Geotechnical and Geoenvironmental Engineering 138, no. 6 (2012): 658–70. http://dx.doi.org/10.1061/(asce)gt.1943-5606.0000636.

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Chun, J. A., R. A. Cooke, J. W. Eheart, and J. Cho. "Estimation of flow and transport parameters for woodchip-based bioreactors: II. field-scale bioreactor." Biosystems Engineering 105, no. 1 (2010): 95–102. http://dx.doi.org/10.1016/j.biosystemseng.2009.09.018.

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Jin, Weiwei. "Regulation Mechanism and Optimization Strategy of Microbial Metabolism in Bioreactor." Research in Health Science 9, no. 3 (2024): p1. http://dx.doi.org/10.22158/rhs.v9n3p1.

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In this study, the metabolic regulation mechanism of microorganisms in bioreactor was discussed, and a series of optimization strategies were proposed based on this. The key effects of metabolic regulation on the performance of bioreactors were revealed through the overview of microbial metabolic pathways and the analysis of regulatory mechanisms. In view of this, the optimization strategy based on metabolic regulation was proposed from the aspects of metabolic engineering transformation, genetic engineering technology application, metabolic pathway reconstruction and optimization. At the same
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Kumon, Hiroki, Shinya Sakuma, Sou Nakamura, Hisataka Maruyama, Koji Eto, and Fumihito Arai. "Microfluidic Bioreactor Made of Cyclo-Olefin Polymer for Observing On-Chip Platelet Production." Micromachines 12, no. 10 (2021): 1253. http://dx.doi.org/10.3390/mi12101253.

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We previously proposed a microfluidic bioreactor with glass–Si–glass layers to evaluate the effect of the fluid force on platelet (PLT) production and fabricated a three-dimensional (3D) microchannel by combining grayscale photolithography and deep reactive ion etching. However, a challenge remains in observing the detailed process of PLT production owing to the low visibility of the microfluidic bioreactor. In this paper, we present a transparent microfluidic bioreactor made of cyclo-olefin polymer (COP) with which to observe the process of platelet-like particle (PLP) production under a brig
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Gao, Yu Bao, Wei Hong Zhou, Lu Shan Cen, Yu Cong Xu, Jiu Xing Liang, and Yu Xi Luo. "The Simplified Flow Field Analysis Method of Multi-Layers Parallel Plates Perfusion Bioreactor." Applied Mechanics and Materials 477-478 (December 2013): 191–96. http://dx.doi.org/10.4028/www.scientific.net/amm.477-478.191.

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Multi-layers parallel plates perfusion bioreactor has the potential advantage in cells cultivation of tissue engineering and good scalability for cells cultivation on a large scale. It is necessary to analyze the distribution of flow shear stress (FSS) of bioreactors which has strong influence on the growth of cells. The result of meshing was not satisfactory because of the complexity of multi-layers parallel plates when using computational fluid dynamics (CFD) to analyze the FSS, and the amount of calculation was great and complex especially under the process of influence on FSS caused by ana
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Tacke, D., J. Pinnekamp, H. Prieske, and M. Kraume. "Membrane bioreactor aeration: investigation of the velocity flow pattern." Water Science and Technology 57, no. 4 (2008): 559–65. http://dx.doi.org/10.2166/wst.2008.123.

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Results of investigations concerning membrane bioreactor aeration are presented which were carried out at the Institute of Environmental Engineering of RWTH Aachen University (ISA) in cooperation with the Department of Chemical Engineering of the Technische Universität Berlin. In the field of industrial and municipal wastewater treatment the use of membrane bioreactors (MBR) is of increasing interest especially due to the high requirements on effluent quality nowadays. The design of aeration systems is a very important aspect of MBR development because it influences both cost of operation and
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Hubert, Casey, and Gerrit Voordouw. "Oil Field Souring Control by Nitrate-Reducing Sulfurospirillum spp. That Outcompete Sulfate-Reducing Bacteria for Organic Electron Donors." Applied and Environmental Microbiology 73, no. 8 (2007): 2644–52. http://dx.doi.org/10.1128/aem.02332-06.

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ABSTRACT Nitrate injection into oil reservoirs can prevent and remediate souring, the production of hydrogen sulfide by sulfate-reducing bacteria (SRB). Nitrate stimulates nitrate-reducing, sulfide-oxidizing bacteria (NR-SOB) and heterotrophic nitrate-reducing bacteria (hNRB) that compete with SRB for degradable oil organics. Up-flow, packed-bed bioreactors inoculated with water produced from an oil field and injected with lactate, sulfate, and nitrate served as sources for isolating several NRB, including Sulfurospirillum and Thauera spp. The former coupled reduction of nitrate to nitrite and
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35

Alves de Oliveira, Luciano, Bryan M. Maxwell, Reid D. Christianson, and Laura E. Christianson. "High-Frequency Bromide Sensor Performance during Denitrifying Bioreactor Tracer Testing." Applied Engineering in Agriculture 39, no. 6 (2023): 639–44. http://dx.doi.org/10.13031/aea.15683.

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Abstract. High-frequency bromide (Br-) sensors could resolve challenges during denitrifying bioreactor tracer tests. Deployment of a Br- sensor during a tracer test resulted in both under- and over-reported concentrations. Collecting high-resolution Br- concentrations generally did not add value to calculated tracer metrics. However, high-frequency Br- sensors were overall considered a convenient tool, in part, due to ease of deployment. Bromide (Br-) tracer tests are an important environmental monitoring method for assessing internal hydraulics in denitrifying woodchip bioreactors. The object
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36

Pazos, Patricia, Salvador Fortaner, and Pilar Prieto. "Long-term In Vitro Toxicity Models: Comparisons Between a Flow-cell Bioreactor, a Static-cell Bioreactor and Static Cell Cultures." Alternatives to Laboratory Animals 30, no. 5 (2002): 515–23. http://dx.doi.org/10.1177/026119290203000505.

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In vitro long-term toxicity testing is becoming an important issue in the field of toxicology, and there is a need to develop new model systems that mimic human chronic exposure and its effects. The aim of this work was to test two long-term in vitro toxicity systems which are available, a flow-cell bioreactor (Tecnomouse) and a static cell bioreactor system (CELLine CL 6-well), and to compare them with the use of conventional cell culture flasks. A human cell line, Int 407, was exposed to cadmium chloride (CdCl2; 10–7–10–8M) for 4 weeks. Cell numbers and cell viabilities were determined by th
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Soudi, Mohammad Reza, Tayebeh Fooladi, Peyman Abdeshahian, et al. "Enhanced Biosurfactant Production by Bacillus pumilus 2IR in Fed-Batch Fermentation Using 5-L Bioreactor." Iranian Journal of Science and Technology, Transaction A: Science 42, no. 3 (2018): 1111–23. https://doi.org/10.1007/s40995-018-0599-4.

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The enhancement of the production of lipopeptide biosurfactant by Bacillus pumilus 2IR as an oil field-isolated bacterium was investigated in the fed-batch fermentation using a 5-L bioreactor. The initial study on the culture medium composition used for biosurfactant synthesis revealed that biosurfactant production was greatly affected by glucose, crude oil, potassium nitrate and ammonium sulfate as pivotal carbon and nitrogen sources which were utilized for biosurfactant synthesis in the bioreactor. The results obtained from the batch fermentation process in the bioreactor showed that the qua
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Maxwell, Bryan M., Richard A. Cooke, Reid D. Christianson, and Laura E. Christianson. "Stage-Discharge Relationships of Drawdown Plates for Denitrifying Woodchip Bioreactors." Applied Engineering in Agriculture 37, no. 6 (2021): 1023–29. http://dx.doi.org/10.13031/aea.14633.

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HighlightsDrawdown plates can prevent prolonged saturation in denitrifying woodchip bioreactors.Contraction coefficients for the orifice equation ranged from 0.74 to 0.76.Drawdown orifice should be sized appropriately to avoid interfering with design flow rates.Established stage-discharge relationships for drawdown orifice improve accuracy of flow monitoring.Abstract.Denitrifying woodchip bioreactors are a conservation drainage practice used to reduce nitrate loads in tile drainage water from field crops. Prolonged saturation in the woodchip media under no flow or low flow conditions can resul
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Nalesso, Federico, Francesco Garzotto, Leda Cattarin, et al. "The Future for End-Stage Kidney Disease Treatment: Implantable Bioartificial Kidney Challenge." Applied Sciences 14, no. 2 (2024): 491. http://dx.doi.org/10.3390/app14020491.

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Despite limited organ availability and post-transplant complications, kidney transplantation remains the optimal treatment for End-Stage Kidney Disease (ESKD). However, innovative dialysis technologies such as portable, wearable, and implantable bioartificial kidney systems are being developed with the aim of addressing these issues and improving patient care. An ideal implantable device could combine bioreactors and blood ultrafiltration to replicate key native cell functions for solute reabsorption, secretion, and endocrinologic activities. Today, the feasibility of an implantable bioreactor
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Borshch, O. O., O. V. Borshch, and M. М. Fedorchenko. "The influence of the method of manure removal and storage on the quality of organic products." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 23, no. 95 (2021): 65–70. http://dx.doi.org/10.32718/nvlvet-a9509.

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The aim of this article was to compare the quality of manure in different ways of its removal and storage for environmental pollution. The research was conducted in three farms of Kyiv region with different methods of manure removal, storage and processing: using deep long-lasting straw litter (manure removal three times a year); with manure processing in a closed bioreactor-fermenter of the closed type; with manure settling in open lagoons. In all farms, the average annual livestock is 400 dairy cows. Samples for analysis of manure (processing waste) were taken the day before export to the fi
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Dutta, Debashis, Prashant Kumar, Ajay Singh, and Shankar Khade. "Bioprocess strategies for enhanced performance in single‐use bioreactors for biomolecule synthesis: A biokinetic approach." Food Bioengineering 3, no. 3 (2024): 337–51. http://dx.doi.org/10.1002/fbe2.12104.

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AbstractSingle‐use bioreactors (SUB) have made a significant impact on the field of bioprocessing, becoming increasingly popular for biomolecule synthesis due to their many advantages, such as minimizing contamination risks and streamlining processes. Extensive research has been conducted on the hydrodynamic conditions within single‐use bioreactors, with a focus on parameters like mixing time, oxygen transfer rate, and stress levels to improve cell cultivation procedures. Several studies have demonstrated that SUB can effectively nurture various cell types, including those that generate monocl
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Ester, S., X. Guo, and A. Delgado. "Numerical simulation of the flow field in a bioreactor." Water Science and Technology 41, no. 4-5 (2000): 207–10. http://dx.doi.org/10.2166/wst.2000.0446.

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In order to give detailed information about the local flow field in a bioreactor a numerical method has been developed. This method gives information about the velocity, pressure and temperature in each point of the reactor, avoiding the problems caused by placing measurement instruments inside. Comparisons of experiments and numerical results show good agreement. The functionality and physical fundamentals of this tool are described. This is followed by explaining a reasonable application of the numerical code in the field of biological reactors. The reactors considered are filled with polydi
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Zaluski, M. H., D. R. Bless, L. Figueroa, and H. O. Joyce. "A Modular Field-Bioreactor for Acid Rock Drainage Treatment." Journal American Society of Mining and Reclamation 2006, no. 2 (2006): 2575. http://dx.doi.org/10.21000/jasmr0602022575.

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Zaluski, M. H., D. R. Bless, L. Figueroa, and H. O. Joyce. "A Modular Field-Bioreactor for Acid Rock Drainage Treatment." Journal American Society of Mining and Reclamation 2006, no. 2 (2006): 2575–84. http://dx.doi.org/10.21000/jasmr06022575.

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Lorenzo, J. C., E. Ojeda, A. Espinosa, and Carlos Borroto. "Field performance of temporary immersion bioreactor-derived sugarcane plants." In Vitro Cellular & Developmental Biology - Plant 37, no. 6 (2001): 803–6. http://dx.doi.org/10.1007/s11627-001-0133-8.

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Méndez-Hernández, Hugo A., Rosa M. Galaz-Ávalos, Ana O. Quintana-Escobar, et al. "In Vitro Conversion of Coffea spp. Somatic Embryos in SETIS™ Bioreactor System." Plants 12, no. 17 (2023): 3055. http://dx.doi.org/10.3390/plants12173055.

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Somatic embryogenesis (SE) is an excellent example of mass plant propagation. Due to its genetic variability and low somaclonal variation, coffee SE has become a model for in vitro propagation of woody species, as well as for large-scale production of vigorous plants that are advantageous to modern agriculture. The success of the large-scale propagation of an embryogenic system is dependent on the development, optimization, and transfer of complementary system technologies. In this study, two successful SE systems were combined with a SETIS™ bioreactor immersion system to develop an efficient
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Dosaev, A. A., R. R. Safarov, and N. V. Menshutina. "Classification analysis of modern bioreactor systems (review). Part 1. Classification of bioreactors by design parameters." Sovremennaya nauka i innovatsii, no. 1 (49) (2025): 106–25. https://doi.org/10.37493/2307-910x.2025.1.9.

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Bioreactors are an integral part of biotechnological processes. Currently, the scope of their application is expanding and covers many areas of human activity. Bioreactor systems are widely used in biotechnological processes for the production of microorganisms, enzymes, cell lines, viruses, recombinant proteins, as well as various products of the food, cosmetic, pharmaceutical, medical, chemical and agricultural industries. It is worth noting that in addition to being used in production, these devices are used in wastewater and soil treatment processes from various waste at production facilit
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48

Krychowska, Agnieszka, Marian Kordas, Maciej Konopacki, et al. "Mathematical Modeling of Hydrodynamics in Bioreactor by Means of CFD-Based Compartment Model." Processes 8, no. 10 (2020): 1301. http://dx.doi.org/10.3390/pr8101301.

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This study presents the procedure of deriving a compartmental model (CM) based on an analysis obtained from the computational fluid dynamics (CFD) model of a bioreactor. The CM is composed of two parts, a structural (that takes into account the architecture of the mathematical model), and a parametric part (which contains the extrinsic parameters of the model). The CM is composed of the branches containing the set of perfectly mixed continuous stirred-tank reactors (CSTRs) in a configuration that matches the bioreactor’s flow patterns. Therefore, this work’s main objective was to develop a mat
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Khalikov, A.M, and E. O. Bozorov. "BIOREACTOR FOR GROWTH OF GREEN ALGAE." JOURNAL OF UNIVERSAL SCIENCE RESEARCH 3, no. 4 (2025): 313–19. https://doi.org/10.5281/zenodo.15308745.

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The article presents information on an optimized variant of growing unicellular green algae and intensifying photosynthetic radiation, namely, the transmission of a moving mechanism using belt drives, in the field of fish farming and animal husbandry<strong>.</strong>
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Sofiyah, Siti Nur, and Achmad Ali Fikri. "UTILIZATION OF ORGANIC WASTE USING TECHNIQUES BIOREACTOR SUBMARINE IN PATI CENTRAL JAVA." RUMPHIUS Pattimura Biological Journal 3, no. 1 (2021): 024–29. http://dx.doi.org/10.30598/rumphiusv3i1p024-029.

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One of the waste that is often found is organic waste. The existence of this waste needs to be handled so that it does not pollute the environment and has more use value. Through proper processing, organic waste can be used as organic fertilizer and biogas. One of the techniques used for this processing is to use the submarine bioreactor technique. This study aims to explore the processing of organic waste in Ngemplak Kidul Margoyoso Pati Village using the submarine bioreactor technique. This research is a field research with a qualitative approach and then analyzed descriptively. The stages o
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