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Dissertations / Theses on the topic 'Field-effect transistor biosensor'

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Published: 4 June 2021

Last updated: 4 February 2022

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1

Chen, Si. "Electronic Sensors Based on Nanostructured Field-Effect Devices." Doctoral thesis, Uppsala universitet, Fasta tillståndets elektronik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-194015.

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Point-of-care (POC) diagnostics presents a giant market opportunity with profound societal impact. In particular, specific detection of DNA and protein markers can be essential for early diagnosis of e.g. cancer, cardiovascular disease, infections or allergies. Today, identification of these markers often requires extensive laboratory work and hence is expensive and time consuming. Current methods for recognition and detection of specific biomolecules are mostly optics based and thus impose severe limitations as to convenience, specificity, sensitivity, parallel processing and cost reduction.

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2

Soy, Esin. "Immobilization Of Proteins On Zeolite And Zeo-type Materials For Biosensor Applications Based On Conductometric Biosensors And Ion Sensitive Field Effect Transistors." Master's thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613313/index.pdf.

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Over the last decade, immobilization of proteins onto inorganic materials is becoming more crucial to extend a deep understanding of interaction between proteins and nanoparticles. With understanding of the real interaction lying under the protein-nanoparticle relations, it is possible to organize the conformation and orientation of surface and framework species of nanoparticles to generate ideal surfaces for potential biotechnological applications. Due to their unique properties such as large clean surface, tunable surface properties, adjustable surface charge, and dispersibility in aqueous s

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3

Han, Yinhua. "Label-free detection of biomolecules by a field effect transistor microarray biosensor with bio-functionalized gate surfaces." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=982123027.

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4

Wang, Dengjun. "Optimization of a biosensor based on an electrolytic gated organic field-effect transistor (EGOFET) for Bisphenol A detection." Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCC089.

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Dans les dernières décennies, en raison de leur utilité potentielle dans le diagnostic clinique, la sécurité alimentaire, la sécurité publique et la surveillance de l'environnement, les biocapteurs ont été intensivement étudiés. Ce travail a porté principalement sur la conception et la fabrication d'un nouveau type de biocapteur basé sur un transistor organique électrolytique à effet de champ (EGOFET). Cette méthode permet de mesurer une faible concentration de bisphénol A dans l'eau avec un EGOFET basé de poly (2,5-bis (3-thiophén-2 tétradécyl-yl) thiéno [3,2-b] thiophène) (pBT1T) en tant le

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5

Ullberg, Nathan. "Field-effect transistor based biosensing of glucose using carbon nanotubes and monolayer MoS2." Thesis, Uppsala universitet, Molekyl- och kondenserade materiens fysik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-397719.

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As part of the EU SmartVista project to develop a multi-modal wearable sensor for health diagnostics, field-effect transistor (FET) based biosensors were explored, with glucose as the analyte, and carbon nanotubes (CNTs) or monolayer MoS2 as the semiconducting sensing layer. Numerous arrays of CNT-FETs and MoS2-FETs were fabricated by photolithographic methods and packaged as integrated circuits. Functionalization of the sensing layer using linkers and enzymes was performed, and the samples were characterized by atomic force microscopy, scanning electron microscopy, optical microscopy, and e

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6

Pregl, Sebastian. "Fabrication and characterization of a silicon nanowire based Schottky-barrier field effect transistor platform for functional electronics and biosensor applications." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-171112.

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This work focuses on the evaluation of the feasibility to employ silicon (Si) nanowire based parallel arrays of Schottky-barrier field effect transistors (SB-FETs) as transducers for potentiometric biosensors and their overall performance as building blocks for novel functional electronics. Nanowire parallel arrays of SB-FETs were produced and electrically characterized during this work. Nominally undoped Si nanowires with mean diameter of 20nm were synthesized by chemical vapor deposition (CVD) driven bottom-up growth and subsequently transferred via a printing process to Si/SiO2 chip substra

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7

Casal, Patricia. "Detection of Protein Analytes in Physiologic Environments via Planar ImmunoHFET." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1354046018.

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8

Pavlásková, Lucie. "Biosenzory na bázi funkcionalizovaného grafenu." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2021. http://www.nusl.cz/ntk/nusl-443227.

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V této práci byl demonstrován grafenový polem řízený transistor (GFET) jako platforma pro detekci glukózy. Sukcinimidyl ester pyrenbutanové kyseliny (PSE) sloužící jako nosič a enzym glukóza oxidáza (GOx) byly úspěšně použity k funkcionalizaci grafenového kanálu ve FE transistoru. Enzym GOx byl imobilizován na kanálu pro glukózovou detekci, jelikož indukuje selektivní katalytickou reakci glukózy. Proces funkcionalizace byl charakterizován pomocí Ramanovy spektroskopie a Atomární silové mikroskopie (AFM). Vyrobený biosenzor na bázi grafenu umožnil elektrickou detekci glukózy ve dvou různých usp

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9

Wang, Yuji. "Ultra-Sensitive AlGaN/GaN HFET Biosensors: Performance Enhancement, Clinical and Food Safety Applications." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1409017537.

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10

Vieira, Nirton Cristi Silva. "Sensores e biossensores baseados em transistores de efeito de campo utilizando filmes automontados nanoestruturados." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-10022012-151657/.

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O transistor de efeito de campo de porta estendida e separada (SEGFET) é um dispositivo alternativo ao tradicional transistor de efeito de campo seletivo a íons (ISFET). A grande vantagem desse dispositivo se refere ao seu fácil processamento, ou seja, se restringe somente a manipulação do eletrodo de porta, evitando processos convencionais de microeletrônica. Neste sentido, sensores iônicos e biossensores podem ser facilmente implementados combinando materiais de reconhecimento químico e/ou biológico. Por sua vez, a técnica de fabricação de filmes finos camada por camada (layer-by-layer, LbL)

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11

Bange, Romain. "Réalisation et optimisation de biocapteurs à base de nanostructures SiC pour la détection électrique d’ADN." Thesis, Université Grenoble Alpes (ComUE), 2019. http://www.theses.fr/2019GREAT007/document.

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La détection de faibles concentrations d’acides nucléiques est essentielle pour certaines applications comme la biologie médicale, où elle permet le diagnostic d’une multitude de pathologies par l’identification de biomarqueurs spécifiques. Par rapport aux techniques traditionnelles de détection par voie biochimique, la détection électrique par effet de champ présente l’avantage d’être une mesure directe, sans marquage, et à réponse rapide. Les transistors à nanofils semiconducteurs sont des dispositifs prometteurs qui permettent potentiellement d’atteindre des limites de détection très basses

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12

Wu, Hao-Hsuan. "Angle-Resolved X-Ray Photoemission Spectroscopy of Self-Assembled Polymer Films on AlGaN/GaN Field Effect Transistors." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1305639462.

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13

Khosravi, Farhad. "Carbon nanotubes micro-arrays: characterization and application in biosensing of free proteins and label-free capture of breast cancer cells." Digital WPI, 2016. https://digitalcommons.wpi.edu/etd-dissertations/347.

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"Circulating tumor cells (CTCs) are cells released into the bloodstream from primary tumors and are suspected to be one of the main causes behind metastatic spreading of cancer. The ability to capture and analyze circulating tumor cells in clinical samples is of great interest in prevailing patient prognosis and clinical management of cancer. Carbon nanotubes, individual rolled-up graphene sheets, have emerged as exciting materials for probing the biomolecular interactions. With diameter of about 1 nm, they can attach themselves to cell surface receptors through specific antibodies and hold a

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14

Pregl, Sebastian Verfasser], Gianaurelio [Akademischer Betreuer] Cuniberti, and Paolo [Akademischer Betreuer] [Lugli. "Fabrication and characterization of a silicon nanowire based Schottky-barrier field effect transistor platform for functional electronics and biosensor applications / Sebastian Pregl. Gutachter: Gianaurelio Cuniberti ; Paolo Lugli. Betreuer: Gianaurelio Cuniberti." Dresden : Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://d-nb.info/1073781143/34.

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15

Pregl, Sebastian [Verfasser], Gianaurelio Akademischer Betreuer] Cuniberti, and Paolo [Akademischer Betreuer] [Lugli. "Fabrication and characterization of a silicon nanowire based Schottky-barrier field effect transistor platform for functional electronics and biosensor applications / Sebastian Pregl. Gutachter: Gianaurelio Cuniberti ; Paolo Lugli. Betreuer: Gianaurelio Cuniberti." Dresden : Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://d-nb.info/1073781143/34.

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16

Ma, Hui. "Nanomaterials for Biological Applications: Drug Delivery and Bio-sensing." ScholarWorks@UNO, 2013. http://scholarworks.uno.edu/td/1647.

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The idea of utilizing nanomaterials in bio-related applications has been extensively practiced during the recent decades. Magnetic nanoparticles (MPs), especially superparamagnetic iron oxide nanoparticles have been demonstrated as promising candidates for biomedicine. A protective coating process with biocompatible materials is commonly performed on MPs to further enhance their colloidal and chemical stability in the physiological environment. Mesoporous hollow silica is another class of important nanomaterials that are extensively studied in drug delivery area for their ability to carry sign

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17

Souza, Jair Fernandes de. "Desenvolvimento de materiais e métodos de fabricação de sensores químicos/bioquímicos baseados em silício e nanoestruturas de carbono (ISFET, CNTFET e GraFET) = Development of materials and methods of fabrication of chemical/biochemical sensors based on silicon and carbon nanostructures (ISFET, CNTFET and GraFET)." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/261064.

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Orientadores: Peter Jürgen Tatsch, José Alexandre Diniz<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Elétrica e de Computação<br>Made available in DSpace on 2018-08-21T00:22:30Z (GMT). No. of bitstreams: 1 Souza_JairFernandesde_D.pdf: 13128989 bytes, checksum: 25325c1093f208d379ae77adc08c90ff (MD5) Previous issue date: 2012<br>Resumo: Este trabalho teve como objetivo o desenvolvimento de materiais e métodos avançados de fabricação de sensores químicos/bioquímicos. Utilizando equipamentos disponíveis no Centro de Componentes Semicondutores da UNICAMP, foram

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18

Villamizar, Gallardo Raquel Amanda. "Biosensors based on carbon nanotube field effect transistors (cntfets) for detecting pathogenic microorganisms." Doctoral thesis, Universitat Rovira i Virgili, 2009. http://hdl.handle.net/10803/9037.

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Microorganisms are present in a variety of sources, including food, water, animals, environment as well as the human body. They can be harmless or harmful. The latter is also called pathogenic and their detection is extremely important due to health and safety reasons. <br/> <br/>It is well known that food contaminated with bacteria can produce a number of foodborne diseases. As a consequence, thousands of euros are invested each year in medical treatments trying to keep the population healthy. There are more than 250 known foodborne diseases. For example, outbreaks of salmonellosis have

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19

Silva, Aldeliane Maria da 1994. "Estudo das características elétricas do biossensor do tipo FET baseado em InP." [s.n.], 2016. http://repositorio.unicamp.br/jspui/handle/REPOSIP/305731.

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Orientadora: Mônica Alonso Cotta<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Física Gleb Wataghin<br>Made available in DSpace on 2018-08-31T00:06:01Z (GMT). No. of bitstreams: 1 Silva_AldelianeMariada_M.pdf: 11574559 bytes, checksum: 5c39733d3a4441b98e7edbef8adbd795 (MD5) Previous issue date: 2016<br>Resumo: Este trabalho apresenta resultados de nossa investigação sobre as propriedades elétricas do biossensor do tipo transistor de efeito de campo (FET, do inglês Field Effect Transistor) baseado em fosfeto de índio (InP). A estrutura deste biossensor consiste e

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Barros, Angélica Denardi de 1982. "Desenvolvimento de filmes finos de TiOx e ZnO para dispositivos ISFET e SAW." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/261292.

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Orientador: José Alexandre Diniz<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Elétrica e de Computação<br>Made available in DSpace on 2018-08-22T13:21:22Z (GMT). No. of bitstreams: 1 Barros_AngelicaDenardide_D.pdf: 3021280 bytes, checksum: 8f60fdfa3cbdfc2f485daac1670de328 (MD5) Previous issue date: 2013<br>Resumo: O objetivo deste trabalho é a obtenção e caracterização de filmes finos de óxido de titânio (TiOx) e de óxido de zinco (ZnO) para aplicações em sensores baseados em transistores de efeito de campo elétrico sensíveis a íons (Ion Sensitive Field Ef

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21

Clarkson, Jeffrey P. "Development of a porous silicon flow-through field effect sensing system for chemical and biological detection /." Link to online version, 2005. http://hdl.handle.net/1850/1074.

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22

Kenaan, Ahmad. "Lipid layers as ultra-thin dielectric for highly sensitive ions field effect transistor sensors." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4002/document.

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Cette thèse vise à développer un capteur d’ions cuivre dans des échantillons humains tels que le plasma ou les urines où l’accumulation des ions induit la maladie de Wilson. Le manque d’outil de diagnostic efficace et non invasif rend cette maladie traitable, potentiellement fatale. Notre capteur, basé sur la technologie des transistors à effet de champ de type metal-oxide-semiconducteur, a l’originalité d’utiliser une monocouche de lipide de type DC8,9PC de 2.4 nm d’épaisseur comme diélectrique de grille. Nous démontrons dans cette thèse que ces lipides peuvent être chimiquement modifiés en d

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23

Veliev, Farida. "Interfacing neurons with nanoelectronics : from silicon nanowires to carbon devices." Thesis, Université Grenoble Alpes (ComUE), 2016. http://www.theses.fr/2016GREAI001/document.

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Dans la lignée des progrès technologiques récents en électronique, ces dernières décennies ont vu l’émergence d’une variété de systèmes permettant l’interface bioélectronique, allant de la mesure de l’activité électrique émise par l’ensemble du cerveau jusqu’à la mesure du signal émis par un neurone unique. Bien que des interfaces électroniques avec les neurones ont montré leur utilité pour des applications cliniques et sont communément utilisés par les neurosciences fondamentales, leurs performances sont encore très limitées, notamment en raison de l’incompatibilité relative entre les système

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24

Truman, Sutanto Pagra. "Multifunktionsfeldeffekttransistoren zur Strömungs-, Chemo- und Biosensorik in Lab on a Chip-Systemen." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2008. http://nbn-resolving.de/urn:nbn:de:bsz:14-ds-1199907096113-76856.

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In dieser Arbeit wird eine neue Methode und ein neuartiges FET -Sensorelement zum Nachweis von Flüssigkeitsbewegungen vorgestellt, das zudem bei Bedarf auch als Chemo- oder Biosensor fungieren kann. Das Einsatzspektrum von FET-basierten Sensoren in Lab on a Chip-Systemen wird dadurch entscheidend erweitert. Bei dem entwickelten FET-Sensor Bauelement handelt es sich um einen normally-on n-leitenden Dünnschichtfeldeffekttransistor mit Ti-Au-Kontakten, basierend auf Silicon-on-Insulator- Substraten, wobei das natürliche Oxid des Siliziumfilms als Schnittstelle zum Elektrolyten bzw. zur Flüssigkei

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Truman, Sutanto Pagra. "Multifunktionsfeldeffekttransistoren zur Strömungs-, Chemo- und Biosensorik in Lab on a Chip-Systemen." Doctoral thesis, Technische Universität Dresden, 2007. https://tud.qucosa.de/id/qucosa%3A25010.

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In dieser Arbeit wird eine neue Methode und ein neuartiges FET -Sensorelement zum Nachweis von Flüssigkeitsbewegungen vorgestellt, das zudem bei Bedarf auch als Chemo- oder Biosensor fungieren kann. Das Einsatzspektrum von FET-basierten Sensoren in Lab on a Chip-Systemen wird dadurch entscheidend erweitert. Bei dem entwickelten FET-Sensor Bauelement handelt es sich um einen normally-on n-leitenden Dünnschichtfeldeffekttransistor mit Ti-Au-Kontakten, basierend auf Silicon-on-Insulator- Substraten, wobei das natürliche Oxid des Siliziumfilms als Schnittstelle zum Elektrolyten bzw. zur Flüssigkei

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26

Thakore, Vaibhav. "Nonlinear dynamic modeling, simulation and characterization of the mesoscale neuron-electrode interface." Doctoral diss., University of Central Florida, 2012. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/5529.

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Extracellular neuroelectronic interfacing has important applications in the fields of neural prosthetics, biological computation and whole-cell biosensing for drug screening and toxin detection. While the field of neuroelectronic interfacing holds great promise, the recording of high-fidelity signals from extracellular devices has long suffered from the problem of low signal-to-noise ratios and changes in signal shapes due to the presence of highly dispersive dielectric medium in the neuron-microelectrode cleft. This has made it difficult to correlate the extracellularly recorded signals with

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27

CHIEN, ZHENG-SHUN, and 簡鉦舜. "Improving the Sensitivity of Polycrystalline Nanowire Field Effect Transistor for Biosensor." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/pqk7n8.

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碩士<br>逢甲大學<br>電子工程學系<br>107<br>The monitoring system of disease has developed rapidly. The requirement for biomedical detection is very high, such as high sensitivity, fast detection, high reliability, and specific detection, etc. Commercial detection techniques like ELISA are highly reliable and sensitive methods, however, the instrumentations are very huge and expensive, and the pre-treatment steps are too complicated and time-consumed. Recently, nanowire field effect transistor has drawn a lot of attention due to its merits such as high sensitivity, label free and real-time detection. This

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Li, Yi-Fen, and 李宜芬. "An Optoelectronic Biosensor for Overcoming the Debye Screening Effect in Field-Effect Transistor Biodetections." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/gy94wc.

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碩士<br>國立臺灣大學<br>化學研究所<br>106<br>Field-effect transistors (FETs) have long been employed as high-sensitive biosensors for detecting biomolecules, but they also encounter a stringent challenge of the Debye screening effect on the signal detection in physiological buffers, which hinders the further applications of FETs in clinical diagnosis. For the Debye screening effect, because the ions and charged molecules in a high-salt buffer, e.g., human serum or urine, will shield the interacting potential exerted by the charged targets toward the sensing channel of an FET, the signals are severely atten

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29

Leyden, Matthew R. "Label free biosensing with carbon nanotube transistors." Thesis, 2011. http://hdl.handle.net/1957/21717.

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As electronics reach nanometer size scales, new avenues of integrating biology and electronics become available. For example, nanoscale field-effect transistors have been integrated with single neurons to detect neural activity. Researchers have also used nanoscale materials to build electronic ears and noses. Another exciting development is the use of nanoscale biosensors for the point-of-care detection of disease biomarkers. This thesis addresses many issues that are relevant for electrical sensing applications in biological environments. As an experimental platform we have used carbon nanot

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Chen, Chien-Hung, and 陳建宏. "The Investigation on Electrical Characteristics of Silicon Nanowire Field-Effect Transistor Based on Biosensor." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/q4ekb3.

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博士<br>國立交通大學<br>生物科技學系<br>105<br>Bio-Information and Communication Technology (BioICT) will become one of largest industry of next generation after the semiconductor field. The BioICT industry will be the interdisciplinary knowledge integration. In last decade, sensor technique represents a “big step forward” due to the progress of semiconductor technology, especially using in bio-sensor, which is important for early detection, rapid intervention, and a possible reduction of the disease occurrence. Another important feature for bio-sensor is the fabrication processing which approach was compar

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Hung, Jia-Yang, and 洪嘉陽. "A Novel Polycrystalline Silicon Nanowire Field Effect Transistor Biosensor for Trace Biomolecular Markers Detection." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/84us7u.

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Chang, Chih-Tien, and 張知天. "Development of an Ion Sensitive Field Effect Transistor Based Urea Biosensor with Solid State Reference Systems." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/66533869028273058557.

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博士<br>國立交通大學<br>電子研究所<br>98<br>In this thesis, a miniaturized urease biosensor constructed with an enzymy field-effect transistor (EnFET) and solid state reference systems were designed and developed. The EnFETs and the reference systems were developed based on the ion-sensitive FET (ISFET) technology. The ISFETs based biosensors have the advantages of rapid response, small size, high input-impedance and low output-impedance as well as the applicability of semiconductor and integrated-circuit technologies. The ISFET, which is a MOSFET with the gate connection separated in the form of a referen

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Mädler, Carsten. "Silicon nanowire field-effect transistors for the detection of proteins." Thesis, 2016. https://hdl.handle.net/2144/19408.

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In this dissertation I present results on our efforts to increase the sensitivity and selectivity of silicon nanowire ion-sensitive field-effect transistors for the detection of biomarkers, as well as a novel method for wireless power transfer based on metamaterial rectennas for their potential use as implantable sensors. The sensing scheme is based on changes in the conductance of the semiconducting nanowires upon binding of charged entities to the surface, which induces a field-effect. Monitoring the differential conductance thus provides information of the selective binding of biological mo

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Chang, Wen-Hung, and 張文鴻. "The Development of A Low-Cost and Portable Measurement System for Polysilicon Nanowire Field Effect Transistor Biosensor Chip." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/19933940597213168393.

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碩士<br>國立交通大學<br>電子物理系所<br>101<br>Mono-crystalline silicon nanowire field effect transistor biosensor chip has become an important key to biochemical sensing, and can be used in new drug development. Its advantages include receptor binding, high sensitivity, specific selectivity, immediate response, label free, less sample requirements and rapid screening of excellent features. Mono-crystalline silicon is too expensive to be used widely. The poly-silicon nanowire field effect transistors are low-cost and commercially available, so last five years they have become important development projects

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Wu, Tzu-Heng, and 吳子珩. "Application of silicon nanowire field-effect transistor biosensor on biochemical study:1. Ultra-highly sensitive and reusable H5N2 influenza virussensor2.Interfacing neurons with a transistor." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/86cuhe.

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碩士<br>國立臺灣大學<br>化學研究所<br>98<br>The bulk of this master thesis is dedicated in studying various biological issues by silicon nanowire field-effect transistor. This study can be divided into two major part: In the first part, we aim to establish a reusable and highly sensitive H5N2 avian influenza virus sensor by disulfide bond based surface modification method. Currently, we are able to detect virus sample of concentration ranging from picomolar to attomolar. The sensitivity and reusability is proven to be genuine through many control experiments, including fluorescence imaging, atomic force mi

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Shen, Shang-Kai, and 沈尚楷. "Effect of the Thickness of Dielectric Layer on Hepatitis B Virus X Protein Detection with Polycrystalline Silicon Nanowire Field Effect Transistor Based Biosensor." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/56zz2b.

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37

Pregl, Sebastian. "Fabrication and characterization of a silicon nanowire based Schottky-barrier field effect transistor platform for functional electronics and biosensor applications." Doctoral thesis, 2014. https://tud.qucosa.de/id/qucosa%3A28755.

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This work focuses on the evaluation of the feasibility to employ silicon (Si) nanowire based parallel arrays of Schottky-barrier field effect transistors (SB-FETs) as transducers for potentiometric biosensors and their overall performance as building blocks for novel functional electronics. Nanowire parallel arrays of SB-FETs were produced and electrically characterized during this work. Nominally undoped Si nanowires with mean diameter of 20nm were synthesized by chemical vapor deposition (CVD) driven bottom-up growth and subsequently transferred via a printing process to Si/SiO2 chip substr

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Han, Yinhua [Verfasser]. "Label-free detection of biomolecules by a field effect transistor microarray biosensor with bio-functionalized gate surfaces / vorgelegt von Yinhua Han." 2006. http://d-nb.info/982123027/34.

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Lai, Wen-Tsan, and 賴文燦. "Poly crystalline silicon nanowire field effect transistor based biosensor for highly sensitive, label-free and real-time detection of enterovirus DNA." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/92173365812167395162.

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碩士<br>國立交通大學<br>生物科技學系<br>98<br>Enterovirus 71 (EV 71) is an important pathogen that causes higher morbidity and mortality in children around the world than those of other non-Polio enteroviruses. Its infection is neurotropic and even followed by rapid deterioration within average 3 days. The standard clinical methods for EV 71 identification require virus isolation in cell culture and reverse transcriptase polymerase chain reactions (RT-PCR). Virus isolation requires 5-10 days and hinders the subsequent treatment and disease control. Poly silicon nanowire field effect transistor has been show

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Chen, Pei-Chi, and 陳姵圻. "Novel micromaching using inductively coupled plasma (ICP) etching for x-ray resonant cavities of sapphire and Laser drilling for AlGaN/GaN field-effect transistor biosensor package." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/mz42pr.

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博士<br>國立清華大學<br>奈米工程與微系統研究所<br>105<br>Microelectromechanical Systems and micromachining is the mainstream of industrial development. Use of traditional machining to make high aspect ratio structure has disadvantages like tool wear, longer processing time and cannot be mass produced. Sapphire is hard and brittle material and it is very difficult to use the traditional mechanical processing methods to process it. In this study, we used electroplated Ni as a mask during sapphire inductively coupled plasma (ICP) etching with Cl2/BCl3/Ar gas mixtures. A gas mixture of Cl2/BCl3/Ar was used to etc

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ANAND, ANKUR, and 安. 古. "Silicon Nanowire Field-Effect Transistors as Biosensors." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/v99p8c.

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博士<br>國立清華大學<br>工程與系統科學系<br>106<br>The growing number of challenges in a wide variety of areas, including biomedicine (medical diagnosis, proteomics, drug screening, and toxicity), food production, chemical analysis, and environmental monitoring, has pushed the challenging demands for novel biosensors. Among different kinds of developed biosensing technologies, silicon nanowires field-effect transistor (SiNW-FET)-based biosensors stand out due to their attractive features, such as label-free and real-time detection, ultrahigh sensitivity, exquisite selectivity, multiplexing, and high integrati

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Ferreira, Cláudia Sofia Rodrigues. "Development of PNA-DNA Field-Effect Transistor-based biosensors." Master's thesis, 2017. http://hdl.handle.net/10362/30801.

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The high demand for devices with higher sensitivity as well cost-efficiency has put tremendous pressure on the biosensors field. The numerous advantages of Field effect transistors (FETs) such as small size, fast response, label free response, and possibility of on-chip integration of biosensor arrays with a future prospect of low-cost mass production, make their development highly desirable. An elec-trochemical deoxyribonucleic acid (DNA) biosensor using a synthesized ferrocene-based DNA interca-lator as a redox marker was investigated. A peptide nucleic acid (PNA) was employed as a capture p

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Saltzgaber, Grant William. "Comparison of carbon nanotube and graphene field-effect transistor biosensors." Thesis, 2012. http://hdl.handle.net/1957/33984.

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Detection of biomolecules is important for the diagnosis and treatment of diseases. Low concentration detection, specific biomolecule detection, and point-of-care use are appealing characteristics for biosensors because of the possibility of early detection and quick results of specific biomolecules. Furthermore, inexpensive biosensors are appealing so that they are accessible to the general population. The biosensors in this study have the potential to satisfy these characteristics. In this study graphene field-effect transistors (G-FET) were fabricated. Graphene was grown using chemical vap

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Lee, mucian, and 李牧謙. "CMOS-Field-Effect Transistors Biosensor for Ultrasensitive Detecting Follicle Stimulating Hormone." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/05924410579852565160.

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Yin, Li-Te, and 殷立德. "Study of Biosensors Based on an Ion Sensitive Field Effect Transistor." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/97040027905372166514.

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Cardoso, Helena Beatriz Gomes. "Development of disposable biosensor for the detection of breast cancer antigen 15-3." Master's thesis, 2019. http://hdl.handle.net/10773/28069.

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This work describes the development of graphene electrochemical biosensors for the detection of CA15-3 protein, a recognized breast cancer tumor marker, using graphene-based field effect transistors (Gr-FET) functionalized with a specific antibody for this protein. The calibration model provided a correlation coefficient of 0.9959 and a detection limit of de 0.07 U mL-1. The recovery values obtained demonstrate its suitability for the quantification of CA15-3 protein in standard solutions. The ELISA method was also used as a comparison method for biosensor validation. Additionally, the feasibi

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Chen, Chih-Wei, and 陳志偉. "Study of Capacitive Extended Gate Nanobelt Field Effect Transistors as Biosensors." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/2jw3n3.

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博士<br>國立交通大學<br>材料科學與工程學系奈米科技碩博士班<br>107<br>This dissertation contains two parts: (1) optimization of a nanobelt field effect transistor (NBFET) with a capacitive extended gate (EG) for biosensing applications, with impacts of the structure of EG on biosensing estimated through simulations; (2) presentation of the design, manufacture and verification of a 8-channel prototype EGFET biosensor. Both pH detection and anti-mouse IgG/mouse IgG conjugation were demonstrated using the prototype EGFET biosensing platform. In the first part, the NBFET fabrication process and electrical characteristics w

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Wen, Yu-Chi, and 温玉琪. "Characteristics of Tip-based Extended Gate Field Effect Transistors as Biosensors." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/46722917367819763300.

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碩士<br>國立交通大學<br>生醫工程研究所<br>105<br>In this thesis, tip-based extended gate field effect transistor is studied as the biosensor. Atomic layer deposition (ALD) was adopted to grow ultra-thin aluminum oxide (Al2O3) film to cover the 0.5 mm aluminum wires with high conformality at 250 C. After Al2O3 deposition, electrochemical impedance spectroscopy (EIS) was adopted to check the surface coverage so that a near ideal capacitive behavior can be achieved. Moreover, the resistance of the tip-based capacitor can be obtained via EIS measurement. The electrical characteristics of tip-based capacitor wer

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Ying-ShuoChiu and 邱英碩. "Investigation of ZnO nanorod/ZnO-based ion-sensitive field-effect-transistor biosensors." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/57393222093124236838.

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博士<br>國立成功大學<br>微電子工程研究所<br>103<br>In this dissertation, the ZnO nanorod/ZnO-based ion-sensitive field-effect-transistor biosensor was successful fabricated using the vapor cooling condensation system and aqueous solution growth method. To effectively minimize the dimension of the extended-gate field-effect-transistor (EGFET)-based biosensors and shorten the path of sensing signal between the sensing head and the field-effect-transistor, the ZnO sensing membrane was integrated with the ZnO-based field-effect-transistor as the ion-sensitive field-effect-transistor (ISFET)-based biosensors. To i

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Hsu, Chia-Wei, and 許家維. "Using Silicon Nanowires Field Effect Transistor as biosensors for Hepatocellular Carcinoma Diagnosis." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/78374912766435983989.

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碩士<br>國立臺灣大學<br>化學研究所<br>101<br>Hepatocellular carcinoma (HCC), one of the most common malignant neoplasms, is closely associated with cirrhosis, but so far with very poor prognosis. Recent clinical studies revealed that alpha-fetoprotein (AFP) and alpha-L-fucosidase (AFU) enzyme play important roles in the early HCC diagnosis, where the simultaneous determination of both activities can drastically increase diagnostic accuracy and sensitivity. In this study, we applied silicon nanowire field-effect transistors (SiNW-FETs) as a sensitive biosensor for the early HCC diagnosis to detect AFU and A

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