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Journal articles on the topic 'Fighting antibiotic resistance'

Author: Grafiati

Published: 11 March 2023

Last updated: 31 July 2025

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1

Goldhaber, M. "Fighting antibiotic resistance." Science 266, no. 5190 (1994): 1462. http://dx.doi.org/10.1126/science.7985006.

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2

Voelker, R. "Fighting Antibiotic Resistance." JAMA: The Journal of the American Medical Association 283, no. 4 (2000): 470—b—470. http://dx.doi.org/10.1001/jama.283.4.470-b.

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3

Voelker, Rebecca. "Fighting Antibiotic Resistance." JAMA 283, no. 4 (2000): 470. http://dx.doi.org/10.1001/jama.283.4.470-jqu90012-3-1.

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4

Brouillette, Monique. "Fighting Antibiotic Resistance with Biology." Inside Precision Medicine 9, no. 4 (2022): 18–20. http://dx.doi.org/10.1089/ipm.09.04.05.

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5

Garg, Ram. "A REVIEW ON ANTIBIOTIC RESISTANCE." Indian Journal of Health Care Medical & Pharmacy Practice 5, no. 1 (2024): 50–56. http://dx.doi.org/10.59551/ijhmp/25832069/2024.5.1.70.

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Antibiotics are ‘wonder drugs’ when it comes to fighting microorganisms. For decades, many antibiotics have been used not only for medicinal purposes but also for preventive use in other industries such as agriculture and livestock. There has certainly been, because microorganisms have become those resistant to conventional antibiotics while the patient is still unaware of emerging resistant. It turns out we have learned that antibiotic resistance is increasing at an alarming rate.A growing list of diseases, ie.pneumonia,tuberculosis and whooping cough, are difficult and sometimes impossible t

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6

Tacconelli, Evelina, and Giulia De Angelis. "Fighting antibiotic resistance all over Europe." Expert Review of Anti-infective Therapy 8, no. 7 (2010): 761–63. http://dx.doi.org/10.1586/eri.10.57.

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7

Levy, Stuart B. "Fighting the Specter of Antibiotic Resistance." Infectious Diseases in Clinical Practice 7, no. 6 (1998): 261–64. http://dx.doi.org/10.1097/00019048-199808000-00006.

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8

Huang, Yuanling, Wenhui Wang, Zhihao Zhang, et al. "Phage Products for Fighting Antimicrobial Resistance." Microorganisms 10, no. 7 (2022): 1324. http://dx.doi.org/10.3390/microorganisms10071324.

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Antimicrobial resistance (AMR) has become a global public health issue and antibiotic agents have lagged behind the rise in bacterial resistance. We are searching for a new method to combat AMR and phages are viruses that can effectively fight bacterial infections, which have renewed interest as antibiotic alternatives with their specificity. Large phage products have been produced in recent years to fight AMR. Using the “one health” approach, this review summarizes the phage products used in plant, food, animal, and human health. In addition, the advantages and disadvantages and future perspe

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Shaale, Maria M., Josiah Mushanyu, Farai Nyabadza, and Samuel M. Nuugulu. "Fighting typhoid fever: Modeling antibiotic resistance and antibiotic switching." Franklin Open 11 (June 2025): 100274. https://doi.org/10.1016/j.fraope.2025.100274.

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10

Plantinga, Nienke L., Bastiaan HJ Wittekamp, Pleun J. van Duijn, and Marc JM Bonten. "Fighting antibiotic resistance in the intensive care unit using antibiotics." Future Microbiology 10, no. 3 (2015): 391–406. http://dx.doi.org/10.2217/fmb.14.146.

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11

Mehrabi, Mohammad Reza, Madjid Soltani, Mohsen Chiani, Kaamran Raahemifar, and Ali Farhangi. "Nanomedicine: New Frontiers in Fighting Microbial Infections." Nanomaterials 13, no. 3 (2023): 483. http://dx.doi.org/10.3390/nano13030483.

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Microbes have dominated life on Earth for the past two billion years, despite facing a variety of obstacles. In the 20th century, antibiotics and immunizations brought about these changes. Since then, microorganisms have acquired resistance, and various infectious diseases have been able to avoid being treated with traditionally developed vaccines. Antibiotic resistance and pathogenicity have surpassed antibiotic discovery in terms of importance over the course of the past few decades. These shifts have resulted in tremendous economic and health repercussions across the board for all socioecon

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12

Dobrovanov, Oleksandr, Oleksandr Nazarchuk, and Katerina Dmitrieva. "Antibiotic resistance and rational outpatient antibiotic treatment of upper respiratory tract infections in children." Perioperaciina Medicina 5, no. 2 (2023): 4–12. http://dx.doi.org/10.31636/prmd.v5i2.1.

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On the eve of the season of respiratory infections, we would like to draw the attention of outpatient doctors to the fact that 80–90 percent of winter diseases affecting the nose, ears, throat and lungs are of viral origin. Improper and excessive consumption of antibiotics increases the risk of antibiotic resistance, and thus humanity enters the post-antibiotic era. The World Health Organization warns that the problems that antibiotic resistance could cause in the future can be compared to the spread of AIDS in the 1980s. The principles of rational use of antibiotics should always be based on

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13

Touza-Otero, Lara, Mariana Landin, and RODRIGUEZ DIAZ RODRIGUEZ DIAZ. "Fighting antibiotic resistance in the local management of bovine mastitis." Biomedicine & Pharmacotherapy 170 (December 2, 2023): 115967. https://doi.org/10.1016/j.biopha.2023.115967.

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Bovine mastitis is a widespread infectious disease with a significant economic burden, accounting for 80 % of the antibiotic usage in dairy animals. In recent years, extensive research has focused on using biomimetic approaches such as probiotics, bacteriocins, bacteriophages, or phytochemicals as potential alternatives to antibiotics. The local administration of therapeutic molecules through the intramammary route is one of the most commonly strategies to manage bovine mastitis. This review highlights the most important findings in this field and discusses their local application in mastitis

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14

Rábano-Blanco, Andrea, Eva María Domínguez-Martís, Diego Gabriel Mosteiro-Miguéns, Manuel Freire-Garabal, and Silvia Novío. "Nursing Students’ Knowledge and Awareness of Antibiotic Use, Resistance and Stewardship: A Descriptive Cross-Sectional Study." Antibiotics 8, no. 4 (2019): 203. http://dx.doi.org/10.3390/antibiotics8040203.

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Antibiotic resistance is an emerging worldwide concern with serious repercussions in terms of morbi-mortality. Bearing in mind that the inadequate use of antibiotics, by healthcare staff as well as by the general population, is one of its main causes, a multidisciplinary approach is required to try to combat it. The aim of the present study was to determine nursing students’ knowledge and awareness of antibiotic use, resistance and stewardship. A cross-sectional design was used. A total of 578 nursing students from the University of Santiago de Compostela (Spain), ≥18 years old of both sexes w

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15

Zhivich, Alexander. "Fighting bacterial resistance: approaches, challenges, and opportunities in the search for new antibiotics. Part 1. Antibiotics used in clinical practice: mechanisms of action and the development of bacterial resistance." Microbiology Independent Research Journal 4, no. 1 (2017): 31–51. https://doi.org/10.18527/2500-2236-2017-4-1-31-51.

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   Hundreds of thousands of people are dying every year in the world from infections caused by drug resistant bacteria. Antibiotic resistance is a rapidly increasing problem mostly as a result of the worldwide overuse and misuse of antibiotics for conditions that do not require them. The rapid spread of antibiotic resistance in bacteria makes it necessary to intensify the development of new antibiotics and new methods to combat drug resistant bacteria. The goal of this publication is to review the approaches to finding new antibiotics that are active against drug resistant bacteria.

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16

Antwi, AN, A. Stewart, and Michelle Crosbie. "Fighting antibiotic resistance: a narrative review of public knowledge, attitudes, and perceptions of antibiotics use." Perspectives in Public Health 140, no. 6 (2020): 338–50. http://dx.doi.org/10.1177/1757913920921209.

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Aims: The aims of this study were to ascertain the comprehensive knowledge, perceptions, and attitudes of people from varying socioeconomic regions towards antibiotic use; identify the misperceptions and malpractices; and inform health policy and practice. Method: EBSCO host databases, PubMed, and Google Scholar were searched to obtain relevant primary research papers within the years 2010–2018. Search phrases included the following: ‘antibiotics use’, ‘community perceptions’, ‘public opinion, knowledge, behaviour, practices, perceptions’. Initially, selected papers were screened using the Pre

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17

Konova, Natalia, Andrey Petrov, Diana Pendicheva, Yavor Assyov, and Emil Gatchev. "Key features of hospitals antibiotic stewardship software solutions needed for successfully optimizing patient outcomes while fighting antibiotic resistance on a global scale – a shared experience." Pharmacia 71 (August 16, 2024): 1–6. https://doi.org/10.3897/pharmacia.71.e130414.

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Antimicrobial resistance threatens the very core of modern medicine and currently costs the EU more than 11.7 billion euro per year. In 2050 it is projected that 10 million people will die from infections with the so called "superbugs". In the past few decades, no entirely new antibiotic groups are being discovered which makes of crucial importance to preserve the effectiveness of the antibiotics we have today for future generations. Antimicrobial stewardship programs worldwide aim to optimize the use of antimicrobials to improve effectiveness, safety and economic feasibility of antibiotics wh

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18

B R, Arpitha, Rakesh G, Aishwarya B S, and Vimala Gandhi. "A Review on Antibiotic Resistance in Bacteria." International Journal for Research in Applied Science and Engineering Technology 10, no. 10 (2022): 536–42. http://dx.doi.org/10.22214/ijraset.2022.47034.

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Abstract: Antibiotics are miracle cures for fighting microorganisms. Treatment for bacterial illnesses is now available thanks to antibiotics. When antibiotics were first developed in the 1900s, it was believed that humanity had defeated microorganisms, but researchers have discovered that antibiotic resistance is rising at a concerning rate. Unfortunately, societal and economic circumstances, as well as the abuse and misuse of antibiotics in recent decades, have spread the emergence of antibiotic-resistant bacteria. Both humans and animals are universally at risk from the emergence and spread

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19

Koba, Igor S., Viktor V. Stepanishin, Tatiana E. Denisenko, Sergey Yu Filippov, and Gleb V. Kondratov. "Advanced training of veterinary specialists on the spread of antibiotic resistance and the implementation of measures to contain it." Veterinariya, Zootekhniya i Biotekhnologiya 1, no. 11 (2021): 16–26. http://dx.doi.org/10.36871/vet.zoo.bio.202111002.

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Currently, antibiotic resistance poses a serious threat to humanity. The resistance of microorganisms to antibiotics does not increase the financial costs of fighting pathogens, but it is also a problem of ensuring food security. The use of antibiotics in animal husbandry and veterinary medicine for the treatment and prevention of diseases or as growth promoters allows resistant bacteria and resistance genes to be transmitted through the food chain from farm animals to humans. In crop production and horticulture, these drugs are also used to suppress pathogens, prevent diseases and increase th

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20

Jubair, Najwan, Mogana Rajagopal, Sasikala Chinnappan, Norhayati Binti Abdullah, and Ayesha Fatima. "Review on the Antibacterial Mechanism of Plant-Derived Compounds against Multidrug-Resistant Bacteria (MDR)." Evidence-Based Complementary and Alternative Medicine 2021 (August 16, 2021): 1–30. http://dx.doi.org/10.1155/2021/3663315.

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Microbial resistance has progressed rapidly and is becoming the leading cause of death globally. The spread of antibiotic-resistant microorganisms has been a significant threat to the successful therapy against microbial infections. Scientists have become more concerned about the possibility of a return to the pre-antibiotic era. Thus, searching for alternatives to fight microorganisms has become a necessity. Some bacteria are naturally resistant to antibiotics, while others acquire resistance mainly by the misuse of antibiotics and the emergence of new resistant variants through mutation. Sin

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21

Hemank K.C., Rashmi Shrestha, Suraj Vaish, et al. "A situational analysis of antibiotic prescription, dispensing practices and resistance pattern in Nepal: Are we losing the battle?" Magna Scientia Advanced Research and Reviews 10, no. 2 (2024): 197–212. http://dx.doi.org/10.30574/msarr.2024.10.2.0060.

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Background: Antibiotics are widely utilized to treat infections and provide preventative and therapeutic benefits in animal and human healthcare. However, because of the emergence and spread of resistance mechanisms, which cause bacteria to become less susceptible to antibiotics and other treatments and less effective, antimicrobial resistance (AMR) has grown to be one of the most significant worldwide public health concerns. Low- and middle-income countries (LMICs) such as Nepal have a high rate of infectious illnesses and antibiotic resistance, which can lead to both human and financial loss

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22

Konova, Natalia, Andrey Petrov, Diana Pendicheva, Yavor Assyov, and Emil Gatchev. "Key features of hospitals antibiotic stewardship software solutions needed for successfully optimizing patient outcomes while fighting antibiotic resistance on a global scale – a shared experience." Pharmacia 71 (August 16, 2024): 1–6. http://dx.doi.org/10.3897/pharmacia.71.e130414.

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Antimicrobial resistance threatens the very core of modern medicine and currently costs the EU more than 11.7 billion euro per year. In 2050 it is projected that 10 million people will die from infections with the so called “superbugs”. In the past few decades, no entirely new antibiotic groups are being discovered which makes of crucial importance to preserve the effectiveness of the antibiotics we have today for future generations. Antimicrobial stewardship programs worldwide aim to optimize the use of antimicrobials to improve effectiveness, safety and economic feasibility of antibiotics wh

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23

Shang, Zifang, Siew Yin Chan, Qing Song, Peng Li, and Wei Huang. "The Strategies of Pathogen-Oriented Therapy on Circumventing Antimicrobial Resistance." Research 2020 (September 28, 2020): 1–32. http://dx.doi.org/10.34133/2020/2016201.

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The emerging antimicrobial resistance (AMR) poses serious threats to the global public health. Conventional antibiotics have been eclipsed in combating with drug-resistant bacteria. Moreover, the developing and deploying of novel antimicrobial drugs have trudged, as few new antibiotics are being developed over time and even fewer of them can hit the market. Alternative therapeutic strategies to resolve the AMR crisis are urgently required. Pathogen-oriented therapy (POT) springs up as a promising approach in circumventing antibiotic resistance. The tactic underling POT is applying antibacteria

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24

Barac, P., H. Harms, I. Engels, S. Kehraus, T. Schneider, and GM König. "Fighting antibiotic resistance: Resensitizing agents from marine derived fungi." Planta Medica 81, S 01 (2016): S1—S381. http://dx.doi.org/10.1055/s-0036-1596649.

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25

Struwe, Johan. "Fighting antibiotic resistance in Sweden – past, present and future." Wiener klinische Wochenschrift 120, no. 9-10 (2008): 268–79. http://dx.doi.org/10.1007/s00508-008-0977-6.

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26

Lawal, Olabisi Promise, Emmanuel Cherechi Egwuatu, Kunle O. Akanbi, et al. "Fighting Resistance With Data: Leveraging Digital Surveillance to Address Antibiotic Misuse in Nigeria." Path of Science 11, no. 3 (2025): 1009. https://doi.org/10.22178/pos.115-25.

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Antimicrobial resistance (AMR) represents a growing public health challenge in Nigeria. The pervasive misuse of antibiotics, insufficient regulatory frameworks, and inadequate surveillance systems exacerbate this issue. The existing methods for antibiotic monitoring are fragmented and inefficient, hindering the ability to detect real-time resistance patterns. This review delves into the role of digital surveillance technologies in combating AMR, taking advantage of electronic medical records (EMRs), mobile health (mHealth) applications, AI-powered analytics, and cloud-based databases to enhanc

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27

Mia Md Tofayel Gonee Manik. "The Role Of Big Data In Combatting Antibiotic Resistance Predictive Models For Global Surveillance." Nanotechnology Perceptions 16, no. 3 (2020): 361–78. https://doi.org/10.62441/nano-ntp.v16i3.5445.

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The worldwide health emergency of antibiotic resistance makes medical treatments less effective and leads to higher death statistics. The widespread problem of antibiotic resistance stems from the extreme and improper use of antibiotics in medical practices, livestock operations, and agricultural farms. Big data analytics integration serves as an innovative method to predict, monitor, and reduce antibiotic resistance by implementing big data analytics systems. This research adopts a methodical approach to scrutinize the WHO Global Antimicrobial Resistance and Use Surveillance System alongside

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Mia Md Tofayel Gonee Manik. "The Role of Big Data in Combatting Antibiotic Resistance Predictive Models for Global Surveillance." Journal of Information Systems Engineering and Management 10, no. 21s (2025): 939–52. https://doi.org/10.52783/jisem.v10i21s.3462.

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The worldwide health emergency of antibiotic resistance makes medical treatments less effective and leads to higher death statistics. The widespread problem of antibiotic resistance stems from the extreme and improper use of antibiotics in medical practices, livestock operations, and agricultural farms. Big data analytics integration serves as an innovative method to predict, monitor, and reduce antibiotic resistance by implementing big data analytics systems. This research adopts a methodical approach to scrutinize the WHO Global Antimicrobial Resistance and Use Surveillance System alongside

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29

Zhang, Song, Jun Wang, and Juhee Ahn. "Advances in the Discovery of Efflux Pump Inhibitors as Novel Potentiators to Control Antimicrobial-Resistant Pathogens." Antibiotics 12, no. 9 (2023): 1417. http://dx.doi.org/10.3390/antibiotics12091417.

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The excessive use of antibiotics has led to the emergence of multidrug-resistant (MDR) pathogens in clinical settings and food-producing animals, posing significant challenges to clinical management and food control. Over the past few decades, the discovery of antimicrobials has slowed down, leading to a lack of treatment options for clinical infectious diseases and foodborne illnesses. Given the increasing prevalence of antibiotic resistance and the limited availability of effective antibiotics, the discovery of novel antibiotic potentiators may prove useful for the treatment of bacterial inf

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30

Su, Hong Yu (Andrew), and Matt Douglas-Vail. "Addressing the diverging public and physician perceptions on the topic of antibiotic resistance." University of Western Ontario Medical Journal 85, no. 1 (2016): 29–31. http://dx.doi.org/10.5206/uwomj.v85i1.4224.

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Antibiotics are a powerful tool in fighting bacterial infections but with overuse and misuse, resistance is emerging at an alarming rate. To better understand the root causes of resistance, studying the perceptions of both physicians and the general populace may prove beneficial from a health promotion standpoint. Research reveals that diverging views of these 2 groups remain significant, which proves concerning especially in the face of increasingly resistant bacteria and associated mortality. The issue at large, therefore, requires a better understandifrom both parties with regard to antibio

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31

Zhivich, Alexander. "Interference plasmids and their use in combating bacterial resistance." Microbiology Independent Research Journal 6, no. 1 (2019): 37–42. https://doi.org/10.18527/2500-2236-2019-6-1-37-42.

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Fighting against pathogenic bacteria that are resistant to antibiotics has become critical for health care worldwide. More than half a million people die every year from infections caused by drug resistant bacteria. Since bacteria acquire resistance to antibiotics very quickly and the development of new antibiotics is a lengthy process, the search for new approaches to stop the spread of bacterial resistance is extremely important. The spread of antibiotic resistance is accomplished mainly by horizontal gene transfer. Scientists are concentrating their efforts on studying the mechanism of this

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32

Simões, Alexandra S., Daniela A. Alves, João Gregório, et al. "Fighting antibiotic resistance in Portuguese hospitals: Understanding antibiotic prescription behaviours to better design antibiotic stewardship programmes." Journal of Global Antimicrobial Resistance 13 (June 2018): 226–30. http://dx.doi.org/10.1016/j.jgar.2018.01.013.

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33

Tartari, Ermira, Daniela Pires, and Didier Pittet. "Fighting antibiotic resistance is in your hands: May 5, 2017." Lancet Infectious Diseases 17, no. 5 (2017): 475. http://dx.doi.org/10.1016/s1473-3099(17)30182-2.

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34

Touza-Otero, Lara, Mariana Landin, and Patricia Diaz-Rodriguez. "Fighting antibiotic resistance in the local management of bovine mastitis." Biomedicine & Pharmacotherapy 170 (January 2024): 115967. http://dx.doi.org/10.1016/j.biopha.2023.115967.

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35

Dr., Mohammad Nasir Khan, Bibi Najma, and Batool Awan Saima. "One Health Solution for a Sustainable Future of Antibiotic Resistance in the Food Chain." Mader e Milat International Journal of Nursing and Allied Sciences (MINAS) 1, no. 4 (2023): 106–19. https://doi.org/10.5281/zenodo.10448524.

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The food chain has become a silent accomplice in the spread of antibiotic resistance (AMR), jeopardizing our ability to treat life-threatening infections and ensure food security. Excessive antibiotic use in food animals, often for routine prophylaxis and growth promotion, drives the emergence and spread of resistant bacteria, contaminating meat, and the environment, and potentially reaching human consumers. This research tackles this complex challenge through a multi-pronged One Health approach, recognizing the interconnectedness of human, animal, and environmental health. We propose investig

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36

Banamah, Omar B., Mohammed F. Alsamih, Hatem H. Alshehri, et al. "Chances and prevention of antibiotic resistance in primary health care: literature review." International Journal Of Community Medicine And Public Health 8, no. 2 (2021): 875. http://dx.doi.org/10.18203/2394-6040.ijcmph20210030.

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Many concerns have been expressed in the field of clinical practice regarding antimicrobial resistance since many infections with severe complications and bad prognosis have been described since the end of the last century. In primary healthcare facilities, the risks for developing high rates of antibiotic resistance is high, probably due to the high prevalence of bacterial infections in these places, and due to the overuse of antibiotics without any relevance of evidence of bacterial infections. For instance, people usually administer high doses of broad-spectrum antibiotics for non-severe, s

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Baindara, Piyush, and Santi M. Mandal. "Gut-Antimicrobial Peptides: Synergistic Co-Evolution with Antibiotics to Combat Multi-Antibiotic Resistance." Antibiotics 12, no. 12 (2023): 1732. http://dx.doi.org/10.3390/antibiotics12121732.

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Due to huge diversity and dynamic competition, the human gut microbiome produces a diverse array of antimicrobial peptides (AMPs) that play an important role in human health. The gut microbiome has an important role in maintaining gut homeostasis by the AMPs and by interacting with other human organs via established connections such as the gut–lung, and gut–brain axis. Additionally, gut AMPs play a synergistic role with other gut microbiota and antimicrobials to maintain gut homeostasis by fighting against multi-antibiotic resistance (MAR) bacteria. Further, conventional antibiotics intake cre

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Zhang, Yingjie, Juan Yu, Huiru Zhang, Yan Li, and Lu Wang. "Nanofibrous dressing: Potential alternative for fighting against antibiotic‐resistance wound infections." Journal of Applied Polymer Science 139, no. 20 (2022): 52178. http://dx.doi.org/10.1002/app.52178.

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Cansizoglu, Mehmet Fatih, and Erdal Toprak. "Fighting against evolution of antibiotic resistance by utilizing evolvable antimicrobial drugs." Current Genetics 63, no. 6 (2017): 973–76. http://dx.doi.org/10.1007/s00294-017-0703-x.

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40

Andrade, Stéphanie, Maria J. Ramalho, Sílvio B. Santos, et al. "Fighting Methicillin-Resistant Staphylococcus aureus with Targeted Nanoparticles." International Journal of Molecular Sciences 24, no. 10 (2023): 9030. http://dx.doi.org/10.3390/ijms24109030.

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Antimicrobial resistance (AMR) is considered one of the greatest threats to global health. Methicillin-resistant Staphylococcus aureus (MRSA) remains at the core of this threat, accounting for about 90% of S. aureus infections widespread in the community and hospital settings. In recent years, the use of nanoparticles (NPs) has emerged as a promising strategy to treat MRSA infections. NPs can act directly as antibacterial agents via antibiotic-independent activity and/or serve as drug delivery systems (DDSs), releasing loaded antibiotics. Nonetheless, directing NPs to the infection site is fun

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Al-Taweel, Omar, Costa Shubeita, Fairouz Zayed, et al. "Assessment of the rational use of the most commonly prescribed antibiotics at the Department of Health of Ramallah in Palestine." Journal of Infection in Developing Countries 18, no. 12 (2024): 1909–15. https://doi.org/10.3855/jidc.19794.

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Introduction: Appropriate antibiotic use requires using the right antibiotic, at the right dose, for the right duration, and at the right time. Drug-resistant diseases cause numerous deaths globally a year, and antibiotic stewardship is a cornerstone in fighting antibiotic resistance. This study focuses on tracking the antibiotic prescribing practices in Palestine and improving future antibiotic prescribing. Methodology: Data from prescriptions of the most commonly prescribed antibiotics was collected from the Health Department of Ramallah and Al-Bireh clinics between January 1 to March 31, 20

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42

Kesselheim, Aaron S., and Kevin Outterson. "Fighting Antibiotic Resistance: Marrying New Financial Incentives To Meeting Public Health Goals." Health Affairs 29, no. 9 (2010): 1689–96. http://dx.doi.org/10.1377/hlthaff.2009.0439.

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43

Haque, M., Akash Marathakam, Ritesh Rana, et al. "Fighting Antibiotic Resistance: New Pyrimidine-Clubbed Benzimidazole Derivatives as Potential DHFR Inhibitors." Molecules 28, no. 2 (2023): 501. http://dx.doi.org/10.3390/molecules28020501.

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The present work describes the design and development of seventeen pyrimidine-clubbed benzimidazole derivatives as potential dihydrofolate reductase (DHFR) inhibitors. These compounds were filtered by using ADMET, drug-likeness characteristics calculations, and molecular docking experiments. Compounds 27, 29, 30, 33, 37, 38, and 41 were chosen for the synthesis based on the results of the in silico screening. Each of the synthesized compounds was tested for its in vitro antibacterial and antifungal activities using a variety of strains. All the compounds showed antibacterial properties against

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44

Alain Prudence, ISHIMWE, MUTABAZI Donatien, GATEMBEZI Tharcisse, HAKIZIMANA Philippe, KANANURA Viateur, and HABIYAREMYE Lauben. "Isolation and Identification of Pathogenic Bacteria from Urinary Tract Infection in Patients Attending Rwanda Military Hospital." Journal of Drug Delivery and Therapeutics 14, no. 11 (2024): 73–78. http://dx.doi.org/10.22270/jddt.v14i11.6822.

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Background: About 150 million people worldwide are diagnosed with urinary tract infection every year and more than half of women will get at least one in their lifetimes. Overuse and misuse of antibiotics have contributed to the growing problem of resistance amongst uropathogenic bacteria making it hard to treat UTIs. There is an increasing prevalence of antibiotic resistance and that’s why area-specific monitoring studies to document the microorganisms causing UTIs and their antimicrobial susceptibility is mandatory for helping the selection of an effective empirical treatment. Aim: The prese

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Architha, Aithal, Pradhan Abhishek, Aithal Shubhrajyotsna, and R. Shabaraya A. "Complex Determinants Influencing Inappropriate Antibiotic Use - A Systematic Review." International Journal of Health Sciences and Pharmacy (IJHSP) 4, no. 2 (2020): 34–53. https://doi.org/10.5281/zenodo.4381270.

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Antibiotic medicine is a kind of antimicrobial substance used to fight against the bacteria entered to the human body and hence is considered as a most important category of antibacterial agents to fight against bacterial infections either by killing them or inhibiting their growth. Antibiotic medications are widely used both for preventing and curing infections in human beings, animals, and agricultural plants but are not effective against viral infections, such as the common cold, flu, coughs, sore throats, etc. Even though antibiotics found their importance in fighting against bacterial inf

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De Simeis, Davide, and Stefano Serra. "Actinomycetes: A Never-Ending Source of Bioactive Compounds—An Overview on Antibiotics Production." Antibiotics 10, no. 5 (2021): 483. http://dx.doi.org/10.3390/antibiotics10050483.

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The discovery of penicillin by Sir Alexander Fleming in 1928 provided us with access to a new class of compounds useful at fighting bacterial infections: antibiotics. Ever since, a number of studies were carried out to find new molecules with the same activity. Microorganisms belonging to Actinobacteria phylum, the Actinomycetes, were the most important sources of antibiotics. Bioactive compounds isolated from this order were also an important inspiration reservoir for pharmaceutical chemists who realized the synthesis of new molecules with antibiotic activity. According to the World Health Or

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Ero, Rya, Xin-Fu Yan, and Yong-Gui Gao. "Ribosome Protection Proteins—“New” Players in the Global Arms Race with Antibiotic-Resistant Pathogens." International Journal of Molecular Sciences 22, no. 10 (2021): 5356. http://dx.doi.org/10.3390/ijms22105356.

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Bacteria have evolved an array of mechanisms enabling them to resist the inhibitory effect of antibiotics, a significant proportion of which target the ribosome. Indeed, resistance mechanisms have been identified for nearly every antibiotic that is currently used in clinical practice. With the ever-increasing list of multi-drug-resistant pathogens and very few novel antibiotics in the pharmaceutical pipeline, treatable infections are likely to become life-threatening once again. Most of the prevalent resistance mechanisms are well understood and their clinical significance is recognized. In co

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Shaikh, Sibhghatulla, Nazia Nazam, Syed Mohd Danish Rizvi, et al. "Mechanistic Insights into the Antimicrobial Actions of Metallic Nanoparticles and Their Implications for Multidrug Resistance." International Journal of Molecular Sciences 20, no. 10 (2019): 2468. http://dx.doi.org/10.3390/ijms20102468.

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Multiple drug-resistant bacteria are a severe and growing public health concern. Because relatively few antibiotics have been approved over recent years and because of the inability of existing antibiotics to combat bacterial infections fully, demand for unconventional biocides is intense. Metallic nanoparticles (NPs) offer a novel potential means of fighting bacteria. Although metallic NPs exert their effects through membrane protein damage, superoxide radicals and the generation of ions that interfere with the cell granules leading to the formation of condensed particles, their antimicrobial

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Acharya, Pragnya Paramita, and Soumya Jal. "The Ethno-pharmaceuticals Fighting UTI-Resistant Bacteria: Synergistic Potential Exploration." International Journal of Advancement in Life Sciences Research 07, no. 03 (2024): 24–36. http://dx.doi.org/10.31632/ijalsr.2024.v07i03.003.

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Urinary tract infections (UTIs) are a pressing global health concern, exacerbated by the rise of antibiotic-resistant bacterial strains. Bioprospecting, involving the exploration of natural resources for therapeutic potential, offers a promising approach to tackling this challenge. Ethnopharmaceuticals, traditional medicinal practices and remedies from indigenous communities, present a valuable source for discovering novel bioactive compounds. This review comprehensively evaluates the bioprospecting of ethnopharmaceuticals and their synergistic potential against antibiotic-resistant UTIs. Draw

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PARASION, SYLWIA, MAGDALENA KWIATEK, ROMUALD GRYKO, LIDIA MIZAK, and ANNA MALM. "Bacteriophages as an Alternative Strategy for Fighting Biofilm Development." Polish Journal of Microbiology 63, no. 2 (2014): 137–45. http://dx.doi.org/10.33073/pjm-2014-019.

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The ability of microbes to form biofilms is an important element of their pathogenicity, and biofilm formation is a serious challenge for today's medicine. Fighting the clinical complications associated with biofilm formation is very difficult and linked to a high risk of failure, especially in a time of increasing bacterial resistance to antibiotics. Bacterial species most commonly isolated from biofilms include coagulase-negative staphylococci, Staphylococcus aureus, Enterococcus faecalis, Enterococcus faecium, Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Pseudomonas aeruginos

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