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1

Kim, Yang-Ho, and Jae-Heon Lim. "The Reliability and Validity of Figure-of-8 Walk Test in Patients with Stroke." Journal of the Korean Academy of Clinical Electrophysiology 10, no. 1 (2012): 29–37. http://dx.doi.org/10.5627/kace.2012.10.1.029.

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MIZOTA, KATSUHIKO, SHIN MURATA, HIROSHI OTAO, et al. "Validity and reliability of the Figure-of-8 Walk Test in which subjects walk at maximum speeds." Japanese Journal of Health Promotion and Physical Therapy 4, no. 1 (2014): 1–6. http://dx.doi.org/10.9759/hppt.4.1.

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3

Hess, Rebecca J., Jennifer S. Brach, Sara R. Piva, and Jessie M. VanSwearingen. "Walking Skill Can Be Assessed in Older Adults: Validity of the Figure-of-8 Walk Test." Physical Therapy 90, no. 1 (2010): 89–99. http://dx.doi.org/10.2522/ptj.20080121.

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Background The Figure-of-8 Walk Test (F8W) involves straight and curved paths and was designed to represent walking skill in everyday life. Objective The purposes of this study were to validate the measure in older adults with walking difficulties and to explore correlates of the curved-path walking measure not represented by a straight-path walking measure. Design Fifty-one community-dwelling older adults with mobility disability participated in 2 baseline visits as part of an intervention study. Methods The F8W time, steps, and smoothness and measures of gait (gait speed, modified Gait Abnor
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Tominaga, Akihiro, Katsuhiko Mizota, and Hiroshi Otao. "A study on the utility of the Figure-of-8 Walk Test at Maximum Velocities (F8Wmax) ­." Japanese Journal of Health Promotion and Physical Therapy 7, no. 2 (2017): 85–89. http://dx.doi.org/10.9759/hppt.7.85.

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Jin, Youngmi, Yubin Lee, Seiyoun Park, Sangbin Lee, and Chaegil Lim. "Effects of Curved-Path Gait Training on Gait Ability in Middle-Aged Patients with Stroke: Protocol for a Randomized Controlled Trial." Healthcare 11, no. 12 (2023): 1777. http://dx.doi.org/10.3390/healthcare11121777.

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(1) Introduction: This study aimed to investigate the effects of curved-path stride gait training on the gait ability of patients with stroke. (2) Materials and Methods: Thirty patients with stroke were randomly assigned to curved-path stride gait training (n = 15) and general gait training groups (n = 15). Both groups underwent training for 30 min five times a week for 8 weeks. The gait ability of each was assessed using the Dynamic Gait Index (DGI), Timed-Up-and-Go (TUG) test, 10-meter walk test, and Figure-of-8 walk test (F8WT). (3) Results: The curved-path gait training group showed signif
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Nualyong, Tidarat, and Akkradate Siriphorn. "Accuracy of the figure of 8 walk test with and without dual-task to predict falls in older adults." Journal of Bodywork and Movement Therapies 30 (April 2022): 69–75. http://dx.doi.org/10.1016/j.jbmt.2022.02.001.

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Lee, Jung-Lim, Sung-Hwa Ko, Sungchul Huh, et al. "The Safety, Feasibility, and Efficacy of a Structured Individual Exercise Program for Community-Dwelling Stroke Patients." Healthcare 12, no. 22 (2024): 2281. http://dx.doi.org/10.3390/healthcare12222281.

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Introduction: Stroke is a leading cause of mortality and long-term disability worldwide, often resulting in low levels of physical activity post-discharge. A comprehensive exercise program could be a safe method to increase stroke patients’ physical activity and exercise volume. This pilot study examines the effectiveness, safety, and feasibility of a comprehensive exercise regimen for stroke patients residing in the community after discharge. Methods: This single-group pilot study included patients who received inpatient rehabilitation for motor impairment following a stroke. Community-dwelli
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Miller, Carol A., Jennifer E. Williams, Katey L. Durham, Selena C. Hom, and Julie L. Smith. "The effect of a supervised community–based exercise program on balance, balance confidence, and gait in individuals with lower limb amputation." Prosthetics and Orthotics International 41, no. 5 (2017): 446–54. http://dx.doi.org/10.1177/0309364616683818.

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Background:Many individuals with lower limb loss report concern with walking ability after completing structured traditional rehabilitation.Objectives:The purpose of this study was to explore the impact of a supervised community–based exercise program on balance, balance confidence, and gait in individuals with lower limb amputation.Study design:Repeated measures.Methods:The supervised exercise program was offered biweekly for 6 weeks. The GAITRite System by CIR Systems, Inc., the Figure-of-8 Walk Test, and Activity-specific Balance Confidence Scale were used to measure clinical outcomes pre-
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Stigger, Felipe de Souza, Valeska de Moura Gomes Minuscolli, Melina Barbosa Oviedo, and Adriana Torres de Lemos. "Dual-Task Training Effects on Mobility of Older Adults Residents of Porto Alegre: Pilot Study." Lecturas: Educación Física y Deportes 28, no. 303 (2023): 106–17. http://dx.doi.org/10.46642/efd.v28i303.3969.

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Introduction: Balance deficit during gait is a factor that affects older people’s mobility. It’s related to an increased risk of falls, hospitalization, and mortality. Regular physical activity is an easy and low-cost strategy to improve older adults’s functional mobility. Dual-task training is also suggested to improve balance and has been highlighted in the new World Guidelines for Falls Prevention and Management for Older Adults. Objective: This study aimed to evaluate the effects of dual-task training on functional mobility of community-dwelling older adults. Methodology: Volunteers over 6
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Coyle, Peter C., Subashan Perera, Valerie Shuman, Jessie VanSwearingen, and Jennifer S. Brach. "Development and Validation of Person-Centered Cut-Points for the Figure-of-8-Walk Test of Mobility in Community-Dwelling Older Adults." Journals of Gerontology: Series A 75, no. 12 (2020): 2404–11. http://dx.doi.org/10.1093/gerona/glaa035.

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Abstract Background The Figure-of-8-Walk test (F8WT) is a performance measure of the motor skill of walking. Unlike walking speed over a straight path, it captures curved path walking, which is essential to real-world activity, but meaningful cut-points have yet to be developed for the F8WT. Methods A secondary analysis of 421 community-dwelling older adults (mean age 80.7 ± 7.8), who participated in a community-based exercise clinical trial, was performed. Area under receiver operating characteristic curves (AUROCC) were calculated using baseline data, with F8WT performance discriminating dif
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Beisheim, Emma Haldane, Elisa Sarah Arch, John Robert Horne, and Jaclyn Megan Sions. "Performance-based outcome measures are associated with cadence variability during community ambulation among individuals with a transtibial amputation." Prosthetics and Orthotics International 44, no. 4 (2020): 215–24. http://dx.doi.org/10.1177/0309364620927608.

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Background: In the United States, Medicare Functional Classification Level (K-level) guidelines require demonstration of cadence variability to justify higher-level prosthetic componentry prescription; however, clinical assessment of cadence variability is subjective. Currently, no clinical outcome measures are associated with cadence variability during community ambulation. Objectives: Evaluate whether physical performance, i.e. 10-meter Walk Test (10mWT)-based walking speeds, L-Test, and Figure-of-8 Walk Test scores, is associated with community-based cadence variability among individuals wi
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Barker, Karen L., Martha Batting, Michael Schlüssel, and Meredith Newman. "The reliability and validity of the Figure of 8 Walk test in older people with knee replacement: does the setting have an impact?" Physiotherapy 105, no. 1 (2019): 76–83. http://dx.doi.org/10.1016/j.physio.2018.07.003.

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Park, Hyeok, Daeyeol Kim, Han-Seong Jeong, and Sujeong Jang. "Grip Strength as an Indicator of Health in Elderly Females." Healthcare 13, no. 10 (2025): 1127. https://doi.org/10.3390/healthcare13101127.

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This study aimed to determine whether hand grip strength (HGS) could estimate the physical function of older women with or without obesity or sarcopenia in South Jeolla Province, South Korea. Methods: A total of 541 elderly women aged 60–95 years (mean age: 79.87 ± 6.64) participated in the study. Physical function was assessed using HGS, 10 m walk test, figure-of-8 walk test, and 30-s chair stand test. Among the participants, 400 (76.8%) were classified as obese, and 137 (26.3%) had sarcopenia. Results: Results showed that HGS was significantly lower in the sarcopenic group (16.58 ± 2.86 kg)
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Lee, Den-Ching A., Elissa Burton, Claudia Meyer, et al. "The Potential for Effect of a Six-Week Training Program for Gait Aid Use in Older People with Dementia with Unsteadiness of Gait: A Pilot Study." Journal of Clinical Medicine 12, no. 4 (2023): 1574. http://dx.doi.org/10.3390/jcm12041574.

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This study examined the potential for effect of a six-week gait aid training program for people with dementia on spatiotemporal gait outcomes, perception of use, and falls with gait aid use. The program utilised four 30-min physiotherapy home visits, scheduled at weeks 1/2/3/6, and was enhanced by carer-supervised practice. Falls and the physiotherapist’s clinical judgement of participants achieving safe gait aid use during and after the program were described. Perception ratings at each visit were measured using Likert scales which, along with the spatiotemporal outcomes using the gait aid (T
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Khangare, Sarala G., Bhavana S. Mhatre, Saraswati K. Iyer, and Umanjali S. Damke. "Assessment of dynamic balance and bone density in premenopausal and postmenopausal middle-age women: a comparative study." International Journal of Research in Medical Sciences 10, no. 6 (2022): 1315. http://dx.doi.org/10.18203/2320-6012.ijrms20221488.

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Background: Dynamic balance control is required to perform simple and complex mobility task in our day-to-day life. Deficit in balance can results in falls and fractures which can affect health-related quality of life. Menopause is also considered as a risk for fracture due to osteoporosis, which at later life becomes difficult to manage and causes higher morbidity. So, evaluation of balance and bone density is important in middle-age in women, so that we can plan and administer proper treatment strategies at an early stage which can reduce risk of falls and fractures. Therefore, the aim of th
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Dunga, S. K., C. Kavadichanda, and V. Negi. "POS0880 TWO-MINUTE WALK TEST AS A SIMPLE AND OBJECTIVE OUTCOME MEASURE IN IDIOPATHIC INFLAMMATORY MYOSITIS." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 696.2–696. http://dx.doi.org/10.1136/annrheumdis-2021-eular.3461.

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Background:Manual muscle testing (MMT) and Functional index 2(FI-2) are the usual methods in assessing disease activity in IIM1. Limitations of MMT8 include low sensitivity to change, floor/ceiling effect, and under-representation of certain important muscle groups1 while FI-2 takes a longer time to administer. Several Timed function tests (TFTs) like the 2-minute walk test (2MWT) or 30s raise from a chair test and 30s 1kg arm rise test may be better alternatives and less time taking2. Data looking at the performance of these tests are limited to small controlled studies.Objectives:To assess t
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Polevoy, Georgiy, and Héctor Fuentes-Barría. "Desarrollo del rango de movimiento articular, capacidades coordinativas y aptitud física en niñas rusas de 5 a 6 años practicantes de gimnasia rítmica. Estudio transversal (Development of range of motion articular, coordinative abilities, and physical fitness in russian girls aged 5 to 6 practicing rhythmic gymnastics: a cross-sectional study)." Retos 59 (July 29, 2024): 349–56. http://dx.doi.org/10.47197/retos.v59.108750.

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Objetivo: Evaluar la efectividad de los medios y métodos utilizados para desarrollar la movilidad articular, capacidades coordinativas y aptitud física en niñas rusas de entre 5 a 6 años practicantes de gimnasia rítmica. Material y Métodos: Estudio transversal realizado en la Escuela Deportiva No. 1 de Kirov (Rusia) entre noviembre de 2022 y febrero de 2023. Participaron 30 niñas evaluadas en movilidad articular (Split, Twist y Bridge), capacidades coordinativas (Single Leg Standing Balance, "Figure of 8 Walk y Lying Wall Squat), y aptitud física (Long Jump Two Legs, 20-meter Sprint y Hanging
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VanNostrand, Michael, Myeongjin Bae, Natalie Lloyd, Sadegh Khodabandeloo, and Susan L. Kasser. "Beyond the Timed Up and Go: Dual-Task Gait Assessments Improve Fall Risk Detection and Reflect Real-World Mobility in Multiple Sclerosis." Sclerosis 3, no. 3 (2025): 22. https://doi.org/10.3390/sclerosis3030022.

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Background: Falls are common among individuals with multiple sclerosis (MS), yet standard clinical mobility assessments—such as the Timed Up and Go (TUG)—may not fully capture the complexities of real-world ambulation, leading to suboptimal fall identification. There is a critical need to evaluate the ecological validity of these assessments and identify alternative tests that better reflect real-world mobility and more accurately detect falls. This study examined the ecological validity of the TUG and novel dual-task clinical assessments by comparing laboratory-based gait metrics to community
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Choi, Ji-Young, Sung-Min Son, and Se-Hee Park. "A Backward Walking Training Program to Improve Balance and Mobility in Children with Cerebral Palsy." Healthcare 9, no. 9 (2021): 1191. http://dx.doi.org/10.3390/healthcare9091191.

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Background: We studied the effects of motor tasks using backward walking training on balance and gait functions of children with cerebral palsy. This was a single-blinded, randomized controlled trial with a crossover design conducted at a single facility. Methods: Among 12 children with cerebral palsy, the forward (FWG) (n = 6) and backward walking groups (BWG) (n = 6) underwent training three times a week for 4 weeks, 40 min a day. After a 6-week break, the crossover training was conducted. Functional walking variables were measured. Time-Up-and-Go (TUG) test, Figure-8 Walk Test (FW8T), and P
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Muhammad Danial Baig Chughtai, Hadia Khan, Zeeshan Khattak, et al. "Effect of Backward Walking Versus Forward Walking Training on Balance Among Children with Cerebral Palsy." Journal of Health and Rehabilitation Research 4, no. 3 (2024): 1–5. http://dx.doi.org/10.61919/jhrr.v4i3.1455.

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Background: Cerebral palsy is characterized by long-term impairments in movement and posture that limit an individual’s ability to perform daily activities. Effective rehabilitation methods, such as forward and backward walking training, can improve balance and functional mobility in children with cerebral palsy.Objective: To compare the effects of backward walking training versus forward walking training on balance in children with cerebral palsy.Methods: A randomized clinical trial was conducted with 20 children aged 7-14 years, recruited from Children’s Hospital and Jinnah Hospital, Lahore.
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Fischer, Kathelijn, Frank R. Van Genderen, Piet De Kleijn, and Marijke Van den Berg. "Outcome Assessment in Hemophilia: A Pilot Study on Correlation of Different Instruments." Blood 108, no. 11 (2006): 1032. http://dx.doi.org/10.1182/blood.v108.11.1032.1032.

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Abstract Hemophilia is a rare disease, requiring life-long treatment with expensive clotting factor concentrates. Outcome assessment in hemophilia is important to establish both results of treatment, and compare between strategies. Since the 1980s, hemophilia specific assessment tools were available only for radiological (Pettersson score) and clinical (orthopedic joint score) joint damage. Recently, the HAL (Hemophilia Activities List) was developed to assess functional limitations, and the orthopedic joint score was adapted into the HJHS (hemophilia joint health score) to assess more subtle
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Belluscio, Valeria, Gabriele Casti, Marco Ferrari, et al. "Modifications in Prefrontal Cortex Oxygenation in Linear and Curvilinear Dual Task Walking: A Combined fNIRS and IMUs Study." Sensors 21, no. 18 (2021): 6159. http://dx.doi.org/10.3390/s21186159.

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Increased oxygenated hemoglobin concentration of the prefrontal cortex (PFC) has been observed during linear walking, particularly when there is a high attention demand on the task, like in dual-task (DT) paradigms. Despite the knowledge that cognitive and motor demands depend on the complexity of the motor task, most studies have only focused on usual walking, while little is known for more challenging tasks, such as curved paths. To explore the relationship between cortical activation and gait biomechanics, 20 healthy young adults were asked to perform linear and curvilinear walking trajecto
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Moored, Kyle, Breanna Crane, Michelle Carlson, and Andrea Rosso. "Physical and Cognitive Correlates of GPS-Derived Life-Space Characteristics in Older Adults." Innovation in Aging 5, Supplement_1 (2021): 27. http://dx.doi.org/10.1093/geroni/igab046.095.

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Abstract Life-space mobility, movement within one’s living environment, is important for functional independence in later life. It is unclear which life-space characteristics (i.e., space, duration, shape) are most affected by physical and cognitive limitations. GPS-derived measures mitigate recall bias and offer novel ways to characterize life-space. We examined associations between physical and cognitive performance and GPS-derived life-space characteristics. Participants were 164 community-dwelling adults (Age: M=77.3±6.5) from baseline data of a clinical trial to improve walking in older a
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Yeo, J., M. H. Kim, J. W. Park, J. K. Park, and E. B. Lee. "POS0856 CLINICAL UTILITY OF BREATH-HOLDING TEST FOR MEASURING CARDIOPULMONARY FUNCTION IN PATIENTS WITH SYSTEMIC SCLEROSIS." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 682–83. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2273.

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Background:Interstitial lung disease (ILD) and pulmonary arterial hypertension (PAH) are major causes of death in systemic sclerosis (SSc). Six-minute-walk test (6MWT) is a standard outcome measure for exercise capacity in cardiopulmonary diseases. However, the results of 6MWT may not reflect real cardiopulmonary function of SSc patients in whom musculoskeletal system is frequently inflicted.Objectives:This study aimed to evaluate the clinical utility of breath-holding test (BHT) in evaluating cardiopulmonary function in SSc patients, as compared with 6MWT.Methods:Seventy-two patients with SSc
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Belluscio, Valeria, Elena Bergamini, Marco Tramontano, Rita Formisano, Maria Gabriella Buzzi, and Giuseppe Vannozzi. "Does Curved Walking Sharpen the Assessment of Gait Disorders? An Instrumented Approach Based on Wearable Inertial Sensors." Sensors 20, no. 18 (2020): 5244. http://dx.doi.org/10.3390/s20185244.

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Gait and balance assessment in the clinical context mainly focuses on straight walking. Despite that curved trajectories and turning are commonly faced in our everyday life and represent a challenge for people with gait disorders. The adoption of curvilinear trajectories in the rehabilitation practice could have important implications for the definition of protocols tailored on individual’s needs. The aim of this study was to contribute toward the quantitative characterization of straight versus curved walking using an ecological approach and focusing on healthy and neurological populations. T
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Wechalekar, Ashutosh, Darren Foard, Carol Whelan, et al. "Challenges of Using NT-Probnp for Response Assessment in Systemic AL Amyloidosis - Analysis of a Prospective Study." Blood 128, no. 22 (2016): 4511. http://dx.doi.org/10.1182/blood.v128.22.4511.4511.

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Abstract INTRODUCTION Treatment outcomes in AL amyloidosis are dependent on the hematological response to chemotherapy translating into organ responses. Cardiac biomarker, N-terminal brain pro-natriuretic peptide (NT-proBNP), is the main determinant of cardiac response in AL amyloidosis. Strongly supported by the amyloidosis community, the FDA is considering use of NT-proBNP as the primary end point for clinical trials. A number of questions on the exact details on NT-proBNP in AL remain unanswered - rate of decrease over time, timing of NT-proBNP measurement (6 months or 12 months) and values
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Wang, Jianxiong, Yujie Xie, Li Wang, et al. "Hip abductor strength–based exercise therapy in treating women with moderate-to-severe knee osteoarthritis: a randomized controlled trial." Clinical Rehabilitation 34, no. 2 (2019): 160–69. http://dx.doi.org/10.1177/0269215519875328.

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Objective: To investigate whether hip abductor strength–based exercise therapy could result in further function improvement and more pain relief in women with knee osteoarthritis. Design: Randomized controlled trial. Settings: Rehabilitation department of Affiliated Hospital of Southwest Medical University from years 2016 to 2018. Subjects: In total, 82 women aged 50–70 years, with knee osteoarthritis grade II–IV on the Kellgren–Lawrence scale. Intervention: The experimental group engaged in hip abductor strength–based exercises under the supervision of physical therapists (once a day for six
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Gelisanga, Maribeth Anne P., Sarah Faye C. Alano-Ramos, Cynthia D. Ang, and Sharon D. Ignacio. "PHYSICAL ACTIVITY AND FITNESS LEVEL OF HEALTHCARE WORKERS IN A TERTIARY TEACHING HOSPITAL." Philippine Journal of Physical Therapy 3, no. 1 (2024): 40–41. http://dx.doi.org/10.46409/002.hqgq7778.

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Introduction: Physical activity (PA) and health-related fitness (HRF) level are currently considered key factors in public health promotion, and as such, is healthcare workers need to be well because they are not only responsible for themselves, but of their clients as well. To determine the PA and HRF levels of healthcare workers in a tertiary hospital, disaggregated to age, sex, work assignments, and job tenure. Methods: A cross-sectional research design was utilized to assess healthcare employees from the administrative, medical, nursing, and paramedical cohorts. ALPHA-FIT Test Battery was
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Saraf, Santosh L., Vimal K. Derebail, Xu Zhang, Mark T. Gladwin, Victor R. Gordeuk, and Jane A. Little. "Manifestations of Reduced Kidney Function Occur at a Higher Estimated Glomerular Filtration Rate in Sickle Cell Anemia." Blood 134, Supplement_1 (2019): 2268. http://dx.doi.org/10.1182/blood-2019-124737.

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Kidney disease is a common complication in sickle cell anemia (SCA), which leads to increased morbidity and early mortality. The National Kidney Foundation guidelines use an estimated glomerular filtration rate (eGFR) cutoff of 60 mL/min/1.73m2 to define chronic kidney disease (CKD). However, many SCA patients have an elevated baseline eGFR due to low serum creatinine levels from reduced muscle mass, abnormal tubular secretion of serum creatinine into the urine, and/or high cardiac output from the hemolytic anemia (PMID: 23894560, 20185605). The standard definition of CKD may represent a great
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Hicks, Haley, Anthony McBroom, Patrick Roscher, Jessie VanSwearingen, and Kristin Lowry. "Foot Mechanics Define Directional Changes in Curved-Path Walking: New Methods to Assess the Motor Skill of Walking." Innovation in Aging 5, Supplement_1 (2021): 1034–35. http://dx.doi.org/10.1093/geroni/igab046.3700.

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Abstract Although it is essential to navigating the world, curved path walking is a challenge to mediolateral balance control. The focus of previous curved-path walking research was in spatiotemporal characteristics. We quantified the foot-ground interaction, center of pressure (COP) characteristics during non-linear (eg curved-path) walking important to understand the functional mechanics of directional changes for curved paths. We hypothesized the foot mechanics differ between older adults with better versus poorer curved-path walking (Figure of 8 Walk Test, F8W). Twenty-five older adults (m
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Ergelen, R., S. Kutluğ Ağaçkiran, H. Direskeneli, and F. Alibaz-Oner. "AB1521 DOES PATIENT POSITION AFFECT COMMON FEMORAL VEIN WALL THICKNESS MEASUREMENT BY DOPPLER ULTRASONOGRAPHY AS A DIAGNOSTIC TEST?" Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1992.2–1993. http://dx.doi.org/10.1136/annrheumdis-2023-eular.5963.

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BackgroundWe reported the first controlled Doppler ultrasound (US) study demonstrating increased common femoral vein (CFV) thickness in Behçet’s Disease (BD) [1]. We also recently showed that this is a distinctive feature of BD, rarely present in other inflammatory diseases with a specificity higher than 80% for the cut-off value of ≥ 0.5 mm [2]. Standart lower extremity venous Doppler US is performed in erect position for venous thrombosis or insufficiency [3]. However, we measured CFV thickness in supine position in our previous studies.ObjectivesIn this study, we aimed to assess CFV wall th
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Sevik, K., T. Ünver, and B. Unver. "AB0881 COMPARISION OF FUNCTIONAL OUTCOMES BETWEEN PRIMARY AND REVISION TOTAL KNEE ARTHROPLASTY." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1746.1–1746. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4336.

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Background:Total knee arthroplasty (TKA) is the gold-standard treatment for end-stage knee osteoarthritis (OA). An increase in the prevalance of primary and revision TKA is projected due to aging of the population, increase in the obesity and OA prevalence, patients‘ quality of life perceptions and primary TKA procedures. Although TKA reliably improves pain and function; gait ability and function are still low compared to normal levels [1]. It is important to understand the prognosis to decide to undergo a rTKA (revision total knee arthroplasty) or enhance treatment protocols [2].Objectives:Th
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de Voogd, F., E. Van Wassenaer, A. Mookhoek, et al. "P283 Decrease in bowel wall thickness at intestinal ultrasound accurately detects early endoscopic remission and improvement in ulcerative colitis patients on tofacitinib: a longitudinal prospective cohort study." Journal of Crohn's and Colitis 15, Supplement_1 (2021): S315—S317. http://dx.doi.org/10.1093/ecco-jcc/jjab076.408.

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Abstract Background To assess disease activity in ulcerative colitis (UC) intestinal ultrasound (IUS) highly correlates with endoscopic outcomes. However, data on treatment response evaluated with IUS is limited. In this study we aim to evaluate bowel wall thickness (BWT) at follow-up to determine treatment effectiveness in moderate-severe UC patients treated with tofacitinib according to central read endoscopy and histology. Methods Patients with moderate-severe UC (endoscopic Mayo score (EMS)≥2) starting tofacitinib 10 mg bid were included. Disease activity was evaluated by recorded IUS cine
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Bihlet, A. R., I. Byrjalsen, K. Mundbjerg, et al. "POS0104 A PHASE 2B DOUBLE-BLIND PLACEBO-CONTROLLED RANDOMIZED CLINICAL TRIAL OF SB-061, AN AGGRECAN MIMETIC, IN SUBJECTS WITH SYMPTOMATIC KNEE OSTEOARTHRITIS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 265–66. http://dx.doi.org/10.1136/annrheumdis-2023-eular.3275.

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BackgroundOsteoarthritis (OA) is a chronic disease characterized by degradation of joint structures including the subchondral bone, the synovium, and cartilage. Aggrecan constitutes a major component of hyaline cartilage and plays an important role for its normal function. In OA, aggrecan is gradually lost, which together with cytokines, proteases, and circulating pro-inflammatory fragments of hyaluronic acid (HA) further accelerates tissue destruction. SB-061 is an aggrecan mimetic, composed of a backbone of chondroitin sulfate conjugated to a HA peptide coating protein. SB-061 is believed to
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Barker, Karen L., Jonathan Room, Ruth Knight, et al. "Home-based rehabilitation programme compared with traditional physiotherapy for patients at risk of poor outcome after knee arthroplasty: the CORKA randomised controlled trial." BMJ Open 11, no. 8 (2021): e052598. http://dx.doi.org/10.1136/bmjopen-2021-052598.

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ObjectivesTo evaluate whether a home-based rehabilitation programme for people assessed as being at risk of a poor outcome after knee arthroplasty offers superior outcomes to traditional outpatient physiotherapy.DesignA prospective, single-blind, two-arm randomised controlled superiority trial.Setting14 National Health Service physiotherapy departments in the UK.Participants621 participants identified at high risk of a poor outcome after knee arthroplasty using a bespoke screening tool.InterventionsA multicomponent home-based rehabilitation programme delivered by rehabilitation assistants with
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de Voogd, F., M. Duijvestein, C. Ponsioen, M. Löwenberg, G. D’Haens, and K. Gecse. "P411 Baseline Hypertrophy of the Submucosa at intestinal ultrasound predicts Failure of Treatment in patients with ulcerative colitis." Journal of Crohn's and Colitis 15, Supplement_1 (2021): S418—S419. http://dx.doi.org/10.1093/ecco-jcc/jjab076.535.

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Abstract Background Submucosal fibrosis in ulcerative colitis (UC) has been associated with disease severity in colectomy specimens. As intestinal ultrasound (IUS) visualizes all individual wall layers, we aimed to evaluate baseline IUS features to determine endoscopic response and investigate changes in wall layers during anti-inflammatory treatment in patients with UC Methods Moderate-severe UC patients (endoscopic Mayo score (EMS)≥2) extending beyond the rectum starting treatment were included. Simple Clinical Colitis Activity Index (SCCAI), fecal calprotectin (FCP), IUS and endoscopy were
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Torkaman, Giti, Elham Rostami-Mehr, Noushin Bayat, and Maryam Mofid. "Comparing the impact of hyaluronic acid injections and exercise therapy alone and combined on the postural sway and base of support in individuals with knee osteoarthritis: a quasi-experimental study." International Journal of Therapy and Rehabilitation 32, no. 4 (2025): 1–17. https://doi.org/10.12968/ijtr.2024.0086.

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Background/Aims Intra-articular hyaluronic acid injections and exercise therapy have been demonstrated to improve pain in knee osteoarthritis. The aim of this study was to evaluate the effectiveness of intra-articular hyaluronic acid injections and exercise both separately and in combination, on the centre of pressure sway and base of support in individuals with knee osteoarthritis. Methods In this quasi-experimental study, 36 participants with moderate knee osteoarthritis were divided into exercise therapy (n=12), intra-articular hyaluronic acid injection (n=12), and combined (exercise therap
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Gamble, James G., Michelle T. Sugi, and Kalie Tileston. "THE NATURAL HISTORY OF TYPE VII ALL INTRA-EPIPHYSEAL FRACTURES OF THE LATERAL MALLEOLUS." Orthopaedic Journal of Sports Medicine 7, no. 3_suppl (2019): 2325967119S0011. http://dx.doi.org/10.1177/2325967119s00116.

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Background: Inversion-type ankle injuries are common in pediatric athletes, often resulting in lateral malleolar fractures (1). Ogden described the Type VII lateral malleolar physeal fracture as an injury in which the fracture line is totally within the secondary ossification center of the distal fibular epiphysis (2). The purpose of this paper is to report on the outcomes of 31 children participating in various types of sports activities who had sustained a Type VII fracture of the lateral malleolus. Methods: Here we report the results of an IRB approved prospective (longitudinal) cohort stud
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Ufuk, F., and M. Celik. "A 25-year-old female with recurrent abdominal pain." Acta Gastro Enterologica Belgica 85, no. 2 (2022): 418–19. http://dx.doi.org/10.51821/85.2.10151.

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A 25-year-old female patient, who had a history of medical treatment with the diagnosis of asthma for the last two years, presented with complaints of abdominal pain, nausea, and vomiting. Similar complaints recurred several times over the previous two months and regressed spontaneously in his medical history. These symptoms were acute onset and lasted for 6-8 hours. She had no history of weight loss or fever. Family history revealed the patient’s mother had a history of recurrent swelling of the face and lips, which resolved spontaneously, and her father had coronary artery disease. Physical
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Lee, Kyeongbong, and GyuChang Lee. "The Test–Retest Reproducibility, Standard Error Measurement, and Smallest Real Difference of Dynamic Balance Tests in Chronic Stroke Survivors." Applied Sciences 13, no. 11 (2023): 6358. http://dx.doi.org/10.3390/app13116358.

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Background: A dynamic balance assessment of stroke patients is a very important factor in their rehabilitation process. The aim of this study was to investigate the test–retest reproducibility and smallest real differences in the dynamic balance tests of chronic stroke survivors. Methods: This was a methodological study that fifty-three chronic stroke survivors participated in. Dynamic balance tests were performed using the figure of eight walk test, four square step test, and step test. These tests and measurements were performed twice with 1-week intervals and intra-class correlation coeffic
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Havasy, Janice, Xianghua Deng, Scott Rodeo, and Yulei Liu. "Poster 249: Evaluation of ACL Reconstruction Using a Bone-ACL-Bone Complex Allograft in a Rabbit Model." Orthopaedic Journal of Sports Medicine 10, no. 7_suppl5 (2022): 2325967121S0081. http://dx.doi.org/10.1177/2325967121s00810.

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Objectives: Anatomic anterior cruciate ligament (ACL) reconstruction is defined as the restoration of the native insertion sites, tissue dimensions, and collagen orientation. However, the microstructure and composition of standard tendon grafts used for ACL reconstruction differs from ligament. A bone-ACL-bone allograft (B-ACL-B) could represent a potential solution to ACL reconstruction, and thus the purpose of this study is to evaluate incorporation of a B-ACL-B graft used for ACL reconstruction in a rabbit model. Methods: Our study was approved by the Institutional Animal Care and Use Commi
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Patare, Srushti, Dr Maheshwari Harishchandre, and Dr Suvarna Ganvir. "Consequences of COVID-19 in the Status of Physical Fitness in Post COVID Patients: A Cross Sectional Study." VIMS JOURNAL OF PHYSICAL THERAPY 4, no. 1 (2022): 46–52. http://dx.doi.org/10.46858/vimsjpt.4109.

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Introduction- The COVID-19 pandemic caused by the highly infectious SARS-CoV-2 has affected over 15.9 million people across 200 countries and caused more than 643,000 deaths. The coronavirus is a highly infectious virus and spreads through droplets generated during coughing, sneezing, talking, and even breathing. .[1] As the main symptoms reported after COVID-19 are fatigue and dyspnoea, the need of the study is to find out consequences of COVID 19 in status of Physical Fitness with respect to Functional status, endurance and Lung capacity in Post COVID- 19 subjects Aim – To analyse the conseq
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Meyers, Rachel N., Morgan N. Potter, Steven Hobbs, and Aaron Provance. "FINGER STRESS FRACTURES IN YOUTH ELITE ROCK CLIMBERS." Orthopaedic Journal of Sports Medicine 7, no. 3_suppl (2019): 2325967119S0006. http://dx.doi.org/10.1177/2325967119s00065.

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Background: With the inclusion of climbing in the 2020 Olympics, the number of adolescent competitors is on the rise. For the first time in competition history, the 2020 Olympic format requires every climber to compete in a combined format of all three disciplines: bouldering, sport climbing, and speed climbing. For speed climbing specifically, every competitor must compete on the International Federation of Sport Climbing (IFSC) speed wall. Epiphyseal stress fractures to the middle phalanx, also known as growth plate injuries, are almost exclusive to adolescent climbers, and the most common c
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Hitchon, C., R. Marrie, C. N. Bernstein, J. Kim, and S. Obrien. "POS1210 SAFETY AND IMMUNOGENICITY OF COVID-19 VACCINES IN PATIENTS WITH IMMUNE MEDIATED INFLAMMATORY DISEASE." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 933.2–934. http://dx.doi.org/10.1136/annrheumdis-2022-eular.1267.

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BackgroundCOVID-19 vaccination strategies have evolved with increasing vaccine availability and emerging vaccine safety data. While data on immunogenicity and safety of COVID vaccination strategies exists, there is limited data for people with immune mediated inflammatory diseases (IMIDs) such as inflammatory arthritis (IA), systemic autoimmune rheumatic disease (SARD), inflammatory bowel disease (IBD) and multiple sclerosis (MS).ObjectivesIn IMID patients treated with homologous or heterogeneous COVID vaccines, to compare post vaccine IMID disease activity and COVID antibody responses.Methods
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Durie, Brian, Antje Hoering, S. Vincent Rajkumar, et al. "Bortezomib, Lenalidomide and Dexamethasone Vs. Lenalidomide and Dexamethasone in Patients (Pts) with Previously Untreated Multiple Myeloma without an Intent for Immediate Autologous Stem Cell Transplant (ASCT): Results of the Randomized Phase III Trial SWOG S0777." Blood 126, no. 23 (2015): 25. http://dx.doi.org/10.1182/blood.v126.23.25.25.

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Abstract Background: Lenalidomide with dexamethasone (Rd) is a standard of care for patients with previously untreated multiple myeloma. SWOG S0777, a randomized phase III trial, has compared Rd with bortezomib, lenalidomide and dexamethasone (VRd). The primary end point is progression-free survival (PFS) using a pre-specified one-sided stratified log rank test at a significance level of 0.02. The stratification factors are International Staging System (ISS) stage (I, II or III) and intent to transplant (yes or no), a total of 6 strata. Overall response rate (ORR), overall survival (OS) and sa
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Abaza, N. "THU0587 TB OR NOT TB? THIS IS THE QUESTION. CASE REPORT OF AN EXTRAPULMONARY TUBERCULOUS ARTHRITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 535.2–536. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2488.

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Background:Tuberculous (TB) arthritis consists of 1-3% of all TB cases, whereas TB tenosynovitis & bursitis account for 1%. Primarily it involves large joints but occasionally smaller non-weight-bearing joints. Diagnosis is usually delayed due to lack of awareness, radiographic findings & constitutional or pulmonary involvement.Objectives:We aim to increase rheumatologists awareness to detect possible TB etiology for arthritis & tenosynovitis.Methods:Our case is a 32 years old male complaining of polyarthritis of wrists, MCPs, ankle joints 4 months prior to presentation. Patient wa
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Elman, Ari H., Zeba Singh, Heather D. Mannuel, and Mya S. Thein. "Report of Rare Urachal Carcinoma Presenting with Thrombocytopenia and Microangiopathic Hemolytic Anemia." Blood 124, no. 21 (2014): 5026. http://dx.doi.org/10.1182/blood.v124.21.5026.5026.

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Abstract Introduction: Thrombotic microangiopathy (TMA) is clinical syndrome characterized by microvascular thrombosis, consumptive thrombocytopenia and microangiopathic hemolytic anemia (MAHA). It is a feature of a number of clinical conditions, most prominently thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) and rarely an initial manifestation of systemic malignancy. Case: A previously healthy 31-year-old black woman presented to the emergency department with a 2 week history of lower back pain and hematuria and 1 week history of dyspnea on exertion and dizziness. She
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Davergne, T., R. Tekaya, C. Deprouw, et al. "POS0274-HPR BARRIERS TO PHYSICAL ACTIVITY COLLECTED BY THE IFAB QUESTIONNAIRE CORRELATE WITH LEVELS OF PHYSICAL ACTIVITY IN PATIENTS WITH RHEUMATOID ARTHRITIS OR SPONDYLOARTHRITIS: A CROSS-SECTIONAL STUDY OF 150 PATIENTS." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 360.1–361. http://dx.doi.org/10.1136/annrheumdis-2021-eular.1759.

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Background:Physical activity is important for patients with inflammatory arthritis (IA), such as spondyloarthritis (axSpA), rheumatoid arthritis (RA) or psoriatic arthritis (PsA). They are more prone to physical inactivity but derive specific benefits from regular physical activity (1,2). It is not easy to modify physical activity level (3). Barriers and facilitators to physical activity can be assessed through questionnaires (4), however, it is important to demonstrate a link between these explanatory elements and physical activity levels.Objectives:To measure the correlation between barriers
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Gorijavolu, M., C. Kavadichanda, R. Ananthakrishnan, C. Mariaselvam, M. M. Thabah, and V. S. Negi. "POS1212 SERIAL IMAGING CHANGES IN SKELETAL MUSCLE COMPOSITION AND THEIR ASSOCIATION WITH CLINICAL OUTCOMES IN IDIOPATHIC INFLAMMATORY MYOPATHIES." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 939.2–940. http://dx.doi.org/10.1136/annrheumdis-2023-eular.5775.

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BackgroundMuscle weakness in inflammatory myopathies (IIM) is due to muscle-edema, atrophy and fatty-infiltration among which edema is the predominant cause at baseline. Some IIM pateints donot achieve full muscle power even with immunosupressive treatment which mainly targets edema. Serial changes occuring in skeletal muscles visualized on thigh MRI can help understand the failure of complete recovery. Role of Dual energy X-ray Absorptiometry (DXA) assessed skeletal muscle compositon as outcome measure in IIM was not studied previously.ObjectivesTo see the changes in skeletal muscle compositi
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Skov Kragsnaes, M., J. Miguens Blanco, E. Chekmeneva, et al. "POS1083 INCREASED INTESTINAL PERMEABILITY IN PATIENTS WITH PSORIATIC ARTHRITIS CLASSIFIED AS TREATMENT FAILURES DURING THE 26-WEEK FLORA TRIAL." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 868.1–868. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2635.

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BackgroundChanges in the integrity of the intestinal wall may be implicated in the gut-joint axis of inflammatory arthritis.1 Yet, the gut barrier is only poorly evaluated in psoriatic arthritis (PsA).2ObjectivesIn this exploratory study, we evaluated intestinal permeability before and 26 weeks after one faecal microbiota transplantation (FMT) or sham intervention in adults with PsA.MethodsWe have previously reported the clinical results of a 26-week, double-blind, parallel-group, 1:1 randomised, sham-controlled, superiority trial of gastroscopic-guided FMT as an add-on treatment to methotrexa
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