Academic literature on the topic 'Filaria'

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Journal articles on the topic "Filaria"

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CASIRAGHI, M., T. J. C. ANDERSON, C. BANDI, C. BAZZOCCHI, and C. GENCHI. "A phylogenetic analysis of filarial nematodes: comparison with the phylogeny of Wolbachia endosymbionts." Parasitology 122, no. 1 (2001): 93–103. http://dx.doi.org/10.1017/s0031182000007149.

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Infection with the endosymbiotic bacteria Wolbachia is widespread in filarial nematodes. Previous studies have suggested concordance between the phylogeny of Wolbachia with that of their nematode hosts. However, there is only one published molecular phylogenetic study of filarial species, based on the 5S rRNA gene spacer. The phylogeny proposed by this study is partially incongruent with previous classifications of filarial nematodes, based on morphological characters. Furthermore, both traditional classifications and molecular phylogenies are, in part, inconsistent with the phylogeny of Wolbachia. Here we report mitochondrial cytochrome oxidase I (COI) gene sequences for 11 species of filaria and for another spirurid nematode which was included as an outgroup. In addition, 16S rRNA, wsp and ftsZ gene sequences were generated for the Wolbachia of several filarial species, in order to complete the available data sets and further resolve the phylogeny of Wolbachia in nematodes. We used these data to evaluate whether nematode and Wolbachia phylogenies are concordant. Some of the possible phylogenetic reconstructions based on COI gene were congruent with the phylogeny of Wolbachia and supported the grouping of the rodent filaria Litomosoides sigmodontis with the lymphatic filariae (i.e. Brugia spp. and Wuchereria spp.) and the sister group relationship of Dirofilaria spp. and Onchocerca spp. However, the placement of the Wolbachia-free filaria Acanthocheilonema viteae is ambiguous and dependent on the phylogenetic methods used.
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Achary, K. G., M. S. Bal, N. N. Mandal, and A. K. Satapathy. "Increased IgG antibody responses to excretory/secretory antigens in neonates born from mothers infected with filarial nematodes." Journal of Helminthology 91, no. 6 (2016): 752–56. http://dx.doi.org/10.1017/s0022149x16000778.

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AbstractThe present investigation aimed to evaluate the extent to which maternal filarial infection influences IgG subclass immune responses in the cord blood of neonates. Prevalence of antigenaemia was detected using an Og4C3 assay. Filaria-specific IgG subclasses against excretory/secretory antigens were measured by ELISA. Transplacental transfer of circulating filarial antigen (CFA) was observed from 34.8% of CFA-positive mothers to their respective cord bloods. Filaria-specific IgG1, IgG2 and IgG4 responses were significantly higher among cord bloods of infected mothers compared to cord bloods of uninfected mothers. In contrast, the IgG3 response was significantly higher among cord bloods of uninfected mothers. The study shows that transplacental transfer of filarial antigens and filaria-specific IgG4 occurs more in mothers having high worm burdens, and transfer of filaria-specific IgG3 occurs more in the cord blood of uninfected mothers. The findings of the study provide evidence for the development of prenatal sensitization to filarial antigens in utero, and high filaria-specific IgG4 in cord blood may serve as a marker for in-utero sensitization.
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Conga, David Fernandez, Pedro Mayor, Adriano Penha Furtado, Elane Guerreiro Giese, and Jeannie Nascimento dos Santos. "Occurrence of Dipetalonema gracile in a wild population of woolly monkey Lagothrix poeppiigii in the northeastern Peruvian Amazon." Revista Brasileira de Parasitologia Veterinária 27, no. 2 (2018): 154–60. http://dx.doi.org/10.1590/s1984-296120180014.

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Abstract Dipetalonema gracile (Rudolphi, 1809) (Filarioidea: Onchocercidae) is one of six species of cavities filarial parasites of Neotropical non-human primates. The present study recorded the occurrence of D. gracile, provides morphological and morphometric data and extends the geographical distribution. Adult filariae were obtained from the thoracic and abdominal cavities of 38 specimens of woolly monkey, which were used for local human consumption, in the northeastern Peruvian Amazon. Male and female filarids were processed and analysed using light and scanning electron microscopy. Details of the cephalic papillae, post-cloacal bands and papillae, vulva, phasmid position and lateral appendages are showed by scanning electron microscopy and is recorded the occurrencce of Lagothrix poeppigii monkey as a new host of this filaria in the Yavari-Mirin river basin, Peruvian Amazon.
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D., H. Dudhmal, and P. Chavan S. "Problems against Filaria Health Workers in Filaria Endemic Region: A Practical Study." International Journal of Advanced Biotechnology and Research 12, no. 2 (2021): 23–26. https://doi.org/10.5281/zenodo.5595132.

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<strong>ABSTRACT</strong>: Filaria, known to be the second most disabling disease in the world, is a mosquito borne disease caused by <em>Wuchereria bancrofti. </em>Its symptoms include abnormal swellings in the legs, arms and breasts i.e. elephantiasis while accumulation of fluid in the scrotum leads to the formation of Hydrocoele. This disease is found in the tropics and subtropics with over 120 million people affected and 1.34 billion are at risk of Lymphatic Filariasis (LF). The World Health Organization (WHO) has planned LF elimination from the world by the year 2020. For this the endemic countries are implementing various strategies laid down by the WHO. In India, the state governments are working in collaboration with WHO to limit the disability.&nbsp; But, unless the concerned authorities come to know the problems faced by the Filaria workers in endemic regions, it seems a difficult task to identify and limit the filarial transmission. Though the number of filarial cases has declined drastically in the recent past, like Polio, we are near to the elimination of LF from our country. But, there are some loop holes observed in the strategies of the Filaria Control Units. The timing of night clinics is not so useful to collect blood samples having filarial nematodes as the time of their abundance in the blood stream is in between 10pm to 02am.&nbsp; In the initial blood sampling visits with the Filaria workers working under this scheme, it was found that they were facing number of problems which may be the reason for its slow rate of elimination as new cases are still found. So, the current study is an attempt to know these problems in details.
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Albuquerque, C. M. R., and P. J. Ham. "Concomitant malaria (Plasmodium gallinaceum) and filaria (Brugia pahangi) infections in Aedes aegypti: effect on parasite development." Parasitology 110, no. 1 (1995): 1–6. http://dx.doi.org/10.1017/s0031182000080987.

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Mixed infections with malarial (Plasmodium gallinaceum) and filarial (Brugia pahangi) parasites were carried out in 8 trials with filaria susceptible (REFM) and filaria refractory (REP-RR) Aedes aegypti strains. A secondary infection with B. pahangi microfilariae (mff) by intrathoracic inoculation, reduced the development rate of a pre-existing P. gallinaceum infection. The level of reduction ranged from 9·5 to 49% in REFM and from 50 to 90% in REP-RR. An immune response against oocysts was seen as melanization in mosquitoes with a double infection in the strain refractory to B. pahangi (REP-RR) and a reduction in oocyst size in both mosquito strains. Melanization was not observed in mosquitoes infected only with P. gallinaceum. This may indicate that activation of the prophenoloxidase (PPO) cascade in response to mff in the haemolymph can also be addressed against oocysts in the midgut. No significant difference in the number of filarial parasites recovered was observed when comparing groups with a single or double infection. Retardation in development of filaria larvae was observed in mosquitoes with double infection (REFM strain), together with melanization and a higher rate of abnormal development. Nutritional deficiency caused by superinfection might also be responsible for the delay in filarial development and reduced oocyst size.
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Sunderesh Kamal Chander, Preethy R, Sridevi. M, and Yogalakshmi .E. "Asymptomatic Wuchereria Bancrofti Filariasis Discovered from a Dengue Positive Patient: A Case Report from Tamil Nadu." International Journal of Orofacial Biology 6, no. 2 (2022): 1–4. http://dx.doi.org/10.56501/intjorofacbiol.v6i2.594.

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Concurrent infection by dengue and filaria with in a single individual is rarely known. This type of case can present with a very challenging clinical profile to Clinicians and Hematologist. Filarial co-infection can be a risk factor of severity in dengue infection. Filaria is chronic infection while dengue is an acute infection. Filarial infection is endemic in the tropical regions and a public health problem in Africa, Asia. Co-infection with filarial nematodes, if unrecognized, can result in untoward therapeutic consequences. Both Infection is transmitted by mosquito vectors (Culex, Anopheles, Aedes and Mansonia species) and humans are the definitive host. We report a case of co-infection of Wuchereria bancrofti and Dengue, which was diagnosed by peripheral blood smear examination (W. Bancrofti) and NS 1 antigen positivity (Dengue). We present here a case of 20-year-old male with dengue and microfilaria co-infection with bilateral hydrocele.
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Kumar, A., S. Manchanda, PK Panda, M. Jain, V. Kumar, and Ashutosh Biswas. "Dengue Co-Infection Microfilaria Presenting with Intestinal Obstruction: A Case Report." Journal of Bangladesh College of Physicians and Surgeons 37, no. 1 (2018): 35–38. http://dx.doi.org/10.3329/jbcps.v37i1.39290.

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&#x0D; In the recent years morbidity caused by dengue epidemic has been devastating. Confection of dengue malaria and filaria has been reported in literature where in filarial antigen was detected in the patient. Concurrent infection by dengue and filaria with high parsetemic microfilariae load in a single individual is very rarely known. The varied clinical profile in dengue is multifactorial and concurrent co-infection may be one of them. Here in this case of concurrent infection with dengue and filarial, the patient presented with intestinal obstruction which responded dramatically with diethylcarbamizine while other clinicalsyndrome took a long time. Furthermore, if single vector can harbour both the infectious agent, the etiopathogenesis may completely take a different turn and at times project alarming condition.&#x0D; J Bangladesh Coll Phys Surg 2019; 37(1): 35-38
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Jovanovic, Nemanja, Darko Despotovic, Predrag Stepanovic, Milan Rajkovic, and Tamara Ilic. "Clinical-parasitological and epidemiological review of the nematode Acanthocheilonema reconditum." Veterinarski glasnik, no. 00 (2022): 8. http://dx.doi.org/10.2298/vetgl220307008j.

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Acanthocheilonema (Dipetalonema) reconditum is a less pathogenic species of filaria from the superfamily Filarioidea, and which parasitizes in the subcutaneous connective tissue of dogs, hyenas and jackals. The results of epidemiological studies indicate the zoonotic potential of A. reconditum, bearing in mind it can cause infections with clinical disorders in humans. This filaria is spread globally and it is mostly described in geographical areas such as the Mediterranean Basin, the Middle East, South Africa, South America and Oceania, where it is the only or is the most common filaria that infects dogs. The prevalence and distribution of A. reconditum depend mainly on the vector population, impact of environmental factors, and lifestyle of pets and their owners. Apart from the standard parasitological techniques for differential diagnostics of filariae, more attention is being dedicated to the development of protocols that are based on the simultaneous detection of specific DNA regions in each type of individual filaria. Due to its importance for public health, effective vector control is required, as well as regular preventive examinations, reliable diagnostics and therapy for A. reconditum in dogs, and continuous cooperation between veterinary and medical surgeons.
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Anik, Md Khalid Eakbal, Hamida Khanum, Iftekhar Ahmed Rizvi, Shahela Alam, and Hasina Banu. "Epidemiology of lymphatic filariasis in Nilphamari district, Bangladesh." Dhaka University Journal of Biological Sciences 25, no. 2 (2016): 103–11. http://dx.doi.org/10.3329/dujbs.v25i2.46332.

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The present study was carried out in Filaria Hospital of Nilphamari to find out the current status of lymphatic filariasis (LF) in Nilphamari district: An endemic area for lymphatic filariasis in Bangladesh. The inhabitants of the villages, the outdoor patients and hospitalized patients in Filaria Hospital were selected for the study. The current status and the prevalence of filariasis in Nilphamari district was 4.43%, in Nilphamari Sadar was 3.25% and 4.10% in Sayedpur, 4.82% in Domar, 5.86% in Dimla, 3.85% in Joldhaka and 4.70% in Kishoreganj. It was found that 58.84% filarial patients were male and 41.16% were female; highest prevalence of the disease was observed at the age group of 41 - 60 years. Illiteracy and poverty are the important social risk factors of this disease , about 45% patients were illiterate. Most of the infected patients were very poor and belong to low income group. Only 40.5% patients knew about filariasis. Only 26.1% patients used mosquito curtains. During the study period, it was found that 66.15% of hospitalized filarial patients were male and 33.85% were female, in the Filaria Hospital of Nilphamari. The highest outdoor patients in Nilphamari Hospital were of age group 40 - 59 years and 76.22% patients had hydrocele.&#x0D; Dhaka Univ. J. Biol. Sci. 25(2): 103-111, 2016 (July)
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Scheunemann, Johanna F., Frederic Risch, Julia J. Reichwald, et al. "Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode Litomosoides sigmodontis." Vaccines 11, no. 5 (2023): 966. http://dx.doi.org/10.3390/vaccines11050966.

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More than two-hundred-million people are infected with filariae worldwide. However, there is no vaccine available that confers long-lasting protection against filarial infections. Previous studies indicated that vaccination with irradiated infective L3 larvae reduces the worm load. This present study investigated whether the additional activation of cytosolic nucleic acid receptors as an adjuvant improves the efficacy of vaccination with irradiated L3 larvae of the rodent filaria Litomosoides sigmodontis with the aim of identifying novel vaccination strategies for filarial infections. Subcutaneous injection of irradiated L3 larvae in combination with poly(I:C) or 3pRNA resulted in neutrophil recruitment to the skin, accompanied by higher IP-10/CXCL10 and IFN-β RNA levels. To investigate the impact on parasite clearance, BALB/c mice received three subcutaneous injections in 2-week intervals with irradiated L3 larvae in combination with poly(I:C) or 3pRNA prior to the challenge infection. Vaccination with irradiated L3 larvae in combination with poly(I:C) or 3pRNA led to a markedly greater reduction in adult-worm counts by 73% and 57%, respectively, compared to the immunization with irradiated L3 larvae alone (45%). In conclusion, activation of nucleic acid-sensing immune receptors boosts the protective immune response against L. sigmodontis and nucleic acid-receptor agonists as vaccine adjuvants represent a promising novel strategy to improve the efficacy of vaccines against filariae and potentially other helminths.
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Dissertations / Theses on the topic "Filaria"

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Lima, Nathália Ferreira. "Mansonella ozzardi: uma filaria negligenciada que pode modular a resposta imune." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/42/42135/tde-12032018-143909/.

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As infecções humanas com a filaria Mansonella ozzardi ocorrem em focos situados em regiões tropicais e subtropicais da América Central e do Sul e frequentemente coexistem com outras doenças endêmicas tropicais. Na Amazônia brasileira, as infecções são geralmente assintomáticas e a maior parte delas, consequentemente, deixam de ser diagnosticada. As filarioses crônicas, geralmente não tratadas, podem criar um ambiente imunorregulador, caracterizado pela expansão de linfócitos T produtores de IL-10, que mediam a supressão de respostas proliferativas de células T frente a antígenos específicos bem como a antígenos não-relacionados. Neste trabalho, utilizamos marcadores de ativação celular (CD69 e HLA-DR) e de atividade reguladora (CD39, CTLA-4, OX40, GITR, LAG3, PD-1, LAP-TGF-&#946; e TNFRII) para caracterizar populações de células mononucleares de sangue periférico (PBMCs) em indivíduos infectados por M. ozzardi bem como em controles saudáveis de uma área endêmica deste parasito na Amazônia Brasileira. A análise de PBMCs, por citometria de fluxo multiparamétrica de 49 pacientes infectados por M. ozzardi, mostrou que pacientes e controles apresentam proporções similares de Treg clássicas circulantes, no entanto, indivíduos infectados apresentam um aumento da proporção de células CD4+ e células T reguladoras (Tregs) que expressam a molécula CD39. Células Treg CD39+ parecem definir uma população distinta entre as Treg, pois ao compararmos os marcadores de regulação e ativação entre Tregs CD39+ e CD39- encontramos proporções aumentas destes marcadores nas Treg CD39+. O bloqueio dessa molécula em condições de reestimulo celular aumenta a produção de citocinas inflamatórias e diminui a produção de IL-10 confirmando seu papel regulador.<br>Human infections with the filarial parasite Mansonella ozzardi are common in areas of tropical and subtropical Central and South America and often coexist with other endemic tropical diseases, such as malaria. In the Amazonian Basin of Brazil, infections are typically asymptomatic; most of them will remain undiagnosed. These chronic, untreated filarial infections are potentially associated with a regulatory immune environment, dominated by IL-10-producing T-cells, which mediate the suppression of T-cell proliferation in response to filarial and non-related antigens. Here, we used markers of cell activation (CD69 and HLA-DR) and regulatory activity (CD39, CTLA-4, OX40, GITR, and TNFRII) to characterize peripheral-blood mononuclear cell (PBMCs) subpopulations in individuals infected with |M. ozzardi and in healthy controls living in an area of M. ozzardi endemicity in the Brazilian Amazon. Multiparameter flow cytometry analysis of PBMCs from 49 malaria patients showed that patients and controls have similar proportions of classic circulating Tregs, however, the proportion of CD4 + cells and Tregs expressing the CD39 (an ectonucleotidase that regulates the balance of immune responses through Phosphohydrolysis of ATP, an inflammatory molecule in adenosine, an anti-inflammatory molecule), is increased in infected patients. CD39+Treg cells seem to define a distinct population among Tregs, compare activation and regulatory markers between CD39+ and CD39- Tregs - we found increased proportions of these markers in the CD39+ Tregs. Blocking this molecule under cellular restimulation conditions increases production of inflammatory cytokines and decreases IL-10 production, improving its regulatory role.
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Fercoq, Frédéric. "Interactions filaire/poumon dans le modèle murin de filariose Litosomoides sigmodontis." Thesis, Paris, Muséum national d'histoire naturelle, 2017. http://www.theses.fr/2017MNHN0018/document.

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Les filaires sont des nématodes parasites transmis à des vertébrés par des arthropodes hématophages. Les espèces filariennes qui s'installent dans les cavités cœlomiques, les vaisseaux lymphatiques ou des tissus conjonctifs ont leurs stades infestants (ou L3) qui migrent via le système lymphatique après leur inoculation dans la peau. En utilisant le modèle murin avec la filaire Litomosoides sigmodontis dont les adultes résident dans la cavité pleurale, deux phases d'interaction des filaires avec les poumons des souris BALB/c sont décrites 1) lors de la migration des L3 de la peau à la cavité pleurale ; 2) pendant la phase patente de l’infection quand les adultes pondent des microfilaires dans la cavité pleurale. Dans la 1ère phase les L3 rejoignent le système sanguin pulmonaire puis traversent les poumons pour entrer dans la cavité pleurale. Ce passage induit une pathologie aigue transitoire: tout d'abord des hémorragies consécutives à la rupture des capillaires pulmonaires, accompagnées d'une augmentation du nombre de neutrophiles pulmonaires et de la libération transitoire d'IL-1β et des alarmines IL-33 et S100A9 dans la cavité pleurale. Le S100A9 semble faciliter la survie des filaires, soit par un effet anti-inflammatoire soit en facilitant la migration des L3. Les neutrophiles peuvent libérer des NETS en réponse aux L3. Dans les jours suivant l'infection, une réponse régulatrice se met en place dans les poumons, avec le recrutement de macrophages et d'éosinophiles, la production d'IL-4, de CCL2 et d'IL9, ainsi que la baisse d'expression de molécules inflammatoires. La formation des granulomes est également observée dans le tissu pulmonaire. Le passage des L3 induit aussi une inflammation des vaisseaux sanguins pulmonaires chez les souris C57BL/6 seulement. Lors de la phase patente de l'infection, 40% des souris ne développent pas de microfilarémie sanguine. La comparaison des réponses des souris microfilarienne et amicrofilarienne montre une exacerbation de l'inflammation pleurale induite par les microfilaires. De plus, les souris microfilarémiques développent une pathologie pulmonaire dépendant des microfilaires consistant en la fibrose de la plèvre viscérale, une accumulation périvasculaire de macrophages et une inflammation bronchoalvéolaire (production de mucus et éosinophilie). Le contrôle des filaires (adultes et microfilaires), mais aussi la mise en place de la pathologie sont dépendantes de l'IL-5 et de l'IL-4R<br>Filariae are parasitic nematodes transmited to vertebrates by haematophagous arthropods. The filarial species that settle in the coelomic cavities, the lymphatic vessels or the connective tissues have their infectious stages (or L3) which migrate via the lymphatic system after their inoculation into the skin. Using the murine model with the filaria Litomosoides sigmodontis, whose adults reside in the pleural cavity, two phases of interaction between filariae and the lung of BALB/c mice are described 1) during the L3 migration from the skin to the pleural cavity ; 2) during the patent phase of infection, when adults realease microfilariae in the pleural cavity. During the 1st phase L3 join the pulmonary blood system and then cross through the lungs to enter the pleural cavity. This passage induces a transient acute pathology: first haemorrhages following the rupture of the pulmonary capillaries, together with an increase in the number of pulmonary neutrophils and the transient release of IL-1β and the alarmins IL-33 and S100A9 in the pleural cavity. S100A9 appears to facilitate the survival of the filariae either by an anti-inflammatory effect or by facilitating the migration of L3. Neutrophils can release NETs in response to L3. Within days following the infection, a regulatory response takes place in the lungs, with recruitment of macrophages and eosinophils, production of IL-4, CCL2 and IL-9, and downregulation of inflammatory molecules. The formation of granulomas is also observed in pulmonary tissue. The passage of L3 also induces an inflammation of pulmonary blood vessels, in C57BL/6 mice only. During the patent phase of the infection, 40% of the mice do not develop blood microfilaraemia. Comparison of responses of microfilaremic and amicrofilaremic mice shows an exacerbation of pleural inflammation induced by microfilariae. In addition, microfilaremic mice develop microfilaria-dependent pulmonary pathology consisting on fibrosis of the visceral pleura, perivascular accumulation of macrophages and bronchoalveolar inflammation (mucus production and eosinophilia). The control of the filariae (adults and microfilariae), but also the establishment of the pathology are dependent on IL-5 and IL-4R
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Enriconi, Adriana, and 98179-6468. "Determinação da prevalência de Mansonella ozzardi (manson, 1897) (Nematoda: Onchocercidae) em três cidades do Alto Rio Negro, Estado do Amazonas." Universidade Federal do Amazonas, 2004. http://tede.ufam.edu.br/handle/tede/5727.

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Submitted by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2017-07-18T15:09:16Z No. of bitstreams: 2 Dissertação - Adriana Enriconi.pdf: 61716986 bytes, checksum: 9ccf09ac916f5707e21f5119d3f3735f (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2017-07-18T15:09:52Z (GMT) No. of bitstreams: 2 Dissertação - Adriana Enriconi.pdf: 61716986 bytes, checksum: 9ccf09ac916f5707e21f5119d3f3735f (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2017-07-18T15:10:47Z (GMT) No. of bitstreams: 2 Dissertação - Adriana Enriconi.pdf: 61716986 bytes, checksum: 9ccf09ac916f5707e21f5119d3f3735f (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Made available in DSpace on 2017-07-18T15:10:47Z (GMT). No. of bitstreams: 2 Dissertação - Adriana Enriconi.pdf: 61716986 bytes, checksum: 9ccf09ac916f5707e21f5119d3f3735f (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2007-09-27<br>CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>Of the total population of 32.632 inhabitants, above of 18 years, 856 individuals had been evaluated, correspondents to 2.6%, volunteers, not aboriginal messengers and in order to trace the profile epidemiologist in the region. A transversal study was carried through, description and prospective to evaluate the prevalence of Mansonella ozzardi in the cities of SA° Gabriel da Cachoeira, Santa Isabel do Rio Negro and Barcelos, located in the region of the high Negro River, state of Amazon. In samples collected for the method of the thick drop in blade, 22 positive cases in the city had been identified of Sao Gabriel da Cachoeira, correspondents 2.6% of the examined sample, being 68.2% of masculine sex and 31.8% of the feminine sex. The lesser prevalence (1,39%) was found in the 38-47 band years, while that the greater (42,86%) was found in the age band of 58-67years. In the cities of Santa Isabel do Rio Negro and Barcelos the parasitism was not detected. Examinations in children and minors of 18 years had not been carried through. Agriculture was predominant the economic activity in the majority of the infected ones. In relation to the sintomatology of mansonelose, illness transmitted to the man through the bite of arthropods vectors for families Simuliidae and Ceratopogonidae, it was verified that the migraines, pains in the joints and the fatigue in the legs had been more frequent. The presence of visual injuries also was told by some people, what it confirms the studies on the pathology of this illness. The result of this research was informed to the respective Secretariats of Health of the evaluated cities, for the had treatment of the infected individuals.<br>Da população total de 32.632 habitantes, com idade acima de 18 anos, foram avaliados 856 indivíduos, correspondentes à 2,6%, voluntários, ribeirinhos e não indígenas a fim de traçar o perfil epidemiológico na região Foi realizado um estudo transversal, descritivo e prospectivo para avaliar a prevalência de Mansonella ozzardi nos municípios de São Gabriel da Cachoeira, Santa Isabel do Rio Negro e Barcelos, localizados na região do alto Rio Negro, estado do Amazonas. Em amostras coletadas pelo método da gota espessa em lâmina, foram identificados 22 casos positivos no município de São Gabriel da Cachoeira, correspondentes a 2,6% da amostra examinada, sendo 68,2% do sexo masculino e 31,8% do sexo feminino. A menor prevalência (1,39%) foi encontrada na faixa de 38-47 anos, enquanto que a maior (42,86%) foi encontrada na faixa etária de 58-67 anos. Nos municípios de Santa Isabel do Rio Negro e Barcelos não foi detectada a parasitemia. Não foram realizados exames em crianças e menores de 18 anos. A agricultura foi a atividade econômica predominante na maioria dos infectados. Em relação à sintomatologia da mansonelose, doença transmitida ao homem através da picada de artrópodes vetores das famílias Simuliidae e Ceratopogonidae, foi verificado que as dores de cabeça, dores nas articulações e o cansaço nas pernas foram os mais freqüentes. A presença de lesões visuais também foi relatada por algumas pessoas, o que pode indicar determinados estudos sobre a patologia desta doença. O resultado desta pesquisa foi informado às respectivas Secretarias de Saúde dos municípios avaliados, para o tratamento dos indivíduos infectados.
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Klemm, Claudia Ulrike [Verfasser]. "Identification of a putative Litomosoides sigmodontis phosphate permease, Ls-ppe-1, and its role in the interaction between filarial nematodes and their Wolbachia endosymbionts & Establishment of RNA interference in the rodent filaria Litomosoides sigmodontis, a model of human filariasis / Claudia Ulrike Klemm." Bonn : Universitäts- und Landesbibliothek Bonn, 2009. http://d-nb.info/1005973725/34.

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Storey, N. "Immunity to filarial nematodes." Thesis, University of Nottingham, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356035.

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SANTOS, Ana Maria Aguiar dos. "Infecção filarial e alergia." Universidade Federal de Pernambuco, 2012. https://repositorio.ufpe.br/handle/123456789/12966.

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Submitted by Susimery Vila Nova (susimery.silva@ufpe.br) on 2015-04-10T18:59:46Z No. of bitstreams: 2 TESE ARQ ÚNICO - ANA AGUIAR - PPGSCA - CCS-UFPE.pdf: 1310195 bytes, checksum: 04a73c5a56d59e4351b9f828a4ac6d5e (MD5) license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5)<br>Made available in DSpace on 2015-04-10T18:59:46Z (GMT). No. of bitstreams: 2 TESE ARQ ÚNICO - ANA AGUIAR - PPGSCA - CCS-UFPE.pdf: 1310195 bytes, checksum: 04a73c5a56d59e4351b9f828a4ac6d5e (MD5) license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Previous issue date: 2012-08-31<br>A prevalência de infecções helmínticas parasitárias tem declinado em países industrializados e, por outro lado, nas últimas duas a três décadas tem-se observado um significativo aumento na prevalência de doenças auto-imunes e alérgicas nessas regiões. Essas observações despertaram um crescente interesse no estudo da relação entre parasitoses e alergia com base na hipótese de que os helmintos possam causar proteção no desenvolvimento de doenças alérgicas. Contudo, a relação entre doenças parasitárias e alérgicas permanece incerta. Assim sendo, esse trabalho se propôs a investigar, em crianças e adolescentes com filariose bancroftiana residentes na Região Metropolitana do Recife-PE, Brasil, se o comportamento de imunomodulação descrito em indivíduos com infecção filarial pode modificar a resposta alérgica bem como o padrão de produção de citocinas frente à estimulação com antígenos aeroalérgenos e mitógenos. O trabalho foi dividido em três estudos. O primeiro, sob o título “Resposta Imune na filariose bancroftiana e sua repercussão na resposta alérgica” consiste em uma revisão bibliográfica acerca do comportamento da resposta imunológica na filariose linfática, especialmente sobre a capacidade do parasito em modular o sistema imune do hospedeiro, tornando-o tolerante por longo tempo. O trabalho concluiu que seja possível a associação negativa entre a infecção filarial e a resposta aos aeroalérgenos e que esse comportamento possa trazer repercussões futuras com o controle da transmissão obtido através do tratamento em massa. O segundo foi intitulado “Avaliação epidemiológica de doenças negligenciadas em crianças e adolescentes no nordeste do Brasil: filariose linfática e parasitoses intestinais”. Trata-se de um estudo transversal, com 159 infantes na faixa etária de 5 a 18 anos, alunos de escolas públicas municipais, que avaliou a prevalência de infecção filarial e de parasitoses intestinais em escolares numa área endêmica de filariose e refletiu sobre a opção terapêutica utilizada no Brasil no tratamento coletivo para filariose. Ante a prevalência de 13,8% de filariose e 64,2% de parasitoses intestinais, corrobora-se a recomendação da Organização Mundial da Saúde de adição do albendazol ao tratamento da filaríase linfática. O terceiro, sob o título “Resposta alérgica na infecção filarial bancroftiana em crianças e adolescentes”, analisou a hipersensibilidade imediata na infecção filarial. Foram estudados 60 indivíduos, entre crianças e adolescentes, alocadas nos seguintes grupos: I- com infecção filarial e sem doença alérgica; II- sem infecção filarial e com doença alérgica e III- sem infecção filarial e sem doença alérgica. Realizou-se a contagem de eosinófilos e IgE total, além de testes cutâneos de hipersensibilidade imediata para antígenos padronizados de ácaros, fungos, baratas e pelos de gato e cão, bem como dosagem séricas das citocinas IL-4 e IL-5. A avaliação da resposta humoral e celular no grupo com filariose linfática foi semelhante aos outros grupos do estudo. A baixa carga de microfilaremia e a semelhança da origem dos indivíduos de todos os grupos, com provável exposição prévia a outras infecções parasitárias, pode ter colaborado pela uniformidade de resposta imune entre os grupos. Identifica-se a necessidade do estudo de outras citocinas (IL-10, IFN-γ e TGF-β) para a melhor compreensão do fenômeno.
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Delves, C. J. "Developmental processes in filarial worms." Thesis, University of Liverpool, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377098.

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Sereda, Michal Janusz. "Characterization of the molecular and immunological properties of Acanthocheilonema viteae tropomyosin." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2009. http://dx.doi.org/10.18452/15882.

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Diese Arbeit beschreibt die immunologischen Eigenschaften von Acanthochilonema viteae Tropomyosin, einem Muskel-assoziierten Protein. A. viteae ist ein zu den Filarien gehörender Parasit von Gerbilen, ähnlich dem humanpathogenen Filarie Onchocercha volvulus. Diese Arbeit hatte die funktionelle Charakterisierung von A. viteae Tropomyosin im Kontext der natürlichen Infektion und experimentellen Vakzinierung zum Ziel. Das allergene Potential des Tropomyosins und die Produktion von spezifischen IgE-Antikörpern wurden untersucht. Außerdem wurden Tropomyosin-spezifische monoklonale Antikörpern (mAk) entwicklet. Es konnte gezeigt werden, dass Tropomyosin als vielversprechender Kandidat zur Vakzinentwicklung gegen Filariosen angesehen werden kann, wobei berücksichtigt werden muss, dass deutliche Effekte nur unter Th1-Bedingungen auftreten. Die Vakzinierung mit Protein oder DNA reduzierte Adultwurmzahlen um 30 bzw. 45%. Während einer Infektion fungiert Tropomyosin als funktionelles Allergen und führt zur Produktion von hohen Mengen spezifischen IgEs. Ein Screening synthetischer Peptid-Bibliotheken zeigte gemeinsame 13 IgG- und 11 IgE-Epitope. Weiters konnte Kreuzreaktivität mit anderen Tropomyosinen und diesen gemeinsamen IgE-Epitopen nachgewiesen werden. Mit Hilfe von mAk konnte gezeigt werden, dass Tropomyosin auf der Oberfläche der Kutikula der Larvenstadien L3 und microfilariae des Parasiten vorkommt. Durch die Deglykosylierung des nativen Proteins wurde deutlich, dass einige Epitope von posttranslationellen Modifikationen gebildet werden. Weitere Immunisierungen mit Tropomyosin führten zu einem ähnlichen Profil der Zellaktivierung und Antikörperproduktion wie der Adjuvant Aluminiumhydroxid. Jedoch führte die Behandlung zur IL-10 Produktion und zur Zunahme von Gr1+/ CD11b+ Zellpopulationen, welche natürliche Surpressors darstellen. Zusammenfassend kann gesagt werden, dass A. viteae Tropomyosin immunmodulierende Eigenschaften aufweist und als Komponente eines zu entwickelnden Vakzins in Frage kommt.<br>This study describes the immunological properties of Acanthocheilonema viteae muscle-associated protein tropomyosin. A. viteae is a filarial parasite of jirds that resembles the important human parasite Onchocerca volvulus. Focus of experiments is on unraveling the functional properties of tropomyosin in the context of an infection and experimental vaccination. Additionally, allergenic potential of tropomyosin was investigated and the ability to induce high levels of specific IgE. A part of the study was also aimed at the development of anti-tropomyosin monoclonal antibodies (mAb). This study revealed that tropomyosin is a promising antigen for vaccines against filarial nematodes, however, effective only in a Th1 biased environment. Vaccination with protein or DNA resulted in 30% - 45% protection that was not associated with specific IgG or IgE. During infection tropomyosin is an allergen and leads to the production of high levels of specific IgE. Screening of synthetic peptide libraries showed 13 IgG and 11 IgE co-located epitopes and revealed cross-reactivity with other tropomyosins and sharing of IgE epitopes. mAb were raised against A. viteae tropomyosin and showed that tropomyosin is abundant on the cuticle of L3 and microfilariae of the parasite. Deglycosylation of the native protein showed that some epitopes were formed by the posttranslational modifications. Additionally, immunization shows that tropomyosin induces a similar pattern of cell activation and antibody production as aluminium hydroxide adjuvant, but leads to the induction of IL-10 and the increase of population of GR1+/CD11b+ cells. These cells are regarded as natural suppressors. Taken together, results show that A. viteae tropomyosin has immunomodulating properties and can be considered as a component of an efficient vaccine.
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Lima, Ana Wladia Silva de. "Reações adversas ao tratamento em massa com a Dietilcarbamazina em populações de areas endemicas de filariose linfática no Recife - PE." reponame:Repositório Institucional da FIOCRUZ, 2006. https://www.arca.fiocruz.br/handle/icict/3918.

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Made available in DSpace on 2012-05-07T14:43:53Z (GMT). No. of bitstreams: 2 license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) 000009.pdf: 530464 bytes, checksum: 7574dcf7fd4791207d6a2911e4d83a93 (MD5) Previous issue date: 2006<br>Uma das estratégias propostas pela OMS para a erradicação da filariose linfática tem sido o tratamento em massa anual com drogas antifilariais, de populações de áreas endêmicas. Este trabalho teve por objetivo estimar a prevalência de efeitos adversos após o uso da DEC em duas áreas alvo do tratamento em massa e descrever a distribuição, tipo e gravidade das reações adversas e manifestações secundárias, após a dose do medicamento. A pesquisa constou de um estudo de prevalência e de um estudo de série de casos. A dose de DEC administrada na Área I foi de ~ 6 mg/kg/dose para ambos os sexos, tendo por base o peso médio estimado para cada faixa etária. Na Área II, a dose foi semelhante, porém, ajustada de acordo com o sexo. Os dados para o estudo de prevalência foram coletados por meio de um questionário, enquanto para o estudo de série de casos as informações foram obtidas das fichas de notificação preenchidas por profissionais de saúde durante o atendimento. A prevalência de efeitos adversos e seus respectivos intervalos de confiança de 95 por cento foram estimados e a associação entre as variáveis testadas pelo cálculo da Razão de Prevalência, da Diferença de Prevalência, Intervalo de Confiança de 95 por cento e valor de p. Entre as 438 pessoas entrevistadas, na Área I, obteve-se uma prevalência de 23,6 por cento(IC de 95 por cento:19,1-29,5). Na Área II, entre 365 entrevistados, a prevalência foi de 16,2 por cento(IC de 95 por cento: 11,9-21,5). A prevalência de reações adversas foi significativamente mais elevada nas mulheres do que nos homens, na Área I (RP=1,77; IC de 95 por cento: 1,23-2,53). Na Área II, embora a prevalência de efeitos tenha sido maior entre as mulheres, a diferença não foi estatisticamente significante (RP=1,43; IC de 95 por cento: 0,88-2,83). Houve um excesso de prevalência de efeitos adversos na Área I em relação à Área II (DP=7,6; IC de 95 por cento: 2,1-3,4, p=0,007). O cálculo das diferenças de prevalência estratificadas por sexo, na Área I em relação à Área II, constatou um excesso de prevalência no sexo feminino, de 11,1 por cento (IC de 95 por cento: 3,1-19,1; p=0,008). Pela vigilância passiva, foram registrados 58 atendimentos por reações adversas ao DEC, em 2003, e 33 em 2004, a maioria de mulheres (67,3 por cento, em 2003 e 57,6 por cento, em 2004). O maior percentual dos casos foi moderado ou leve. Embora a maior parte das reações adversas tenha sido leve ou moderada, a prevalência foi considerada elevada
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Berbudi, Afiat [Verfasser]. "Filarial infection and filarial antigen administration promotes glucose tolerance in diet-induced obese mice / Afiat Berbudi." Bonn : Universitäts- und Landesbibliothek Bonn, 2015. http://d-nb.info/1080561366/34.

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Books on the topic "Filaria"

1

1942-, Klei Thomas R., and Rajan T. V. 1945-, eds. The filaria. Kluwer Academic Publishers, 2002.

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Zarichnyĭ, O. Mytropolyt Filaret. Lohos, 1995.

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Filaret. Patriarkh Filaret. Vydavnychyi viddil UPT︠S︠ Kyïvsʹkoho Patriarkhatu, 2002.

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Sonin, M. D. Filariata of animals and man and diseases caused by them: Part IV, Onchocerciadae = Filyariaty zhivotnykh i cheloveka i vyzyvaemye imi zabolevaniya : chast chestvertaya, onchocercidae. published for the U.S. Dept. of Agriculture and the National Science Foundation, Washington, D.C. by Amerind Pub. Co., 1985.

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Kontrimavichus, Vitautas Leonovich. Filaroids of domestic and wild animals =: Filyariodidy domashnikh i dikikh zhivotnykh. Published for the United States Dept. of Agriculture and the National Science Foundation, Washington, D.C. by Amerind Pub. Co., 1985.

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Sonin, M. D. Filariata of animals and man and diseases caused by them: Part III, Filariidae, Onchocercinae = Filyarity zhivotnykh i cheloveka i vyzyvaemye imi zabolevaniya : chast tretaya, Filyariidi, Onkhotseriny. Amerind Pub. Co., 1985.

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Romaña, Martín López de. Filagrio y las serpientes. Vida y Espiritualidad, 2004.

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(Project), Madeinfilandia. Made in Filandia 2011. Madeinfilandia, 2012.

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WHO Expert Committee on Filariasis. Lymphatic filariasis: the disease and its control: Fifth report of the WHO Expert Commmittee on Filariasis. World Health Organization, 1992.

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Jędrasik-Jankowska, Inetta. Ubezpieczenie emerytalne: Trzy filary. Wydawn. Prawnicze PWN, 2001.

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Book chapters on the topic "Filaria"

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Mehlhorn, Heinz. "Filaria grassi." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_3870.

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Mehlhorn, Heinz. "Filaria grassi." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27769-6_3870-1.

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Mehlhorn, Heinz. "African Skin Filaria." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_3589.

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Mehlhorn, Heinz. "Moving Skin Filaria." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_4079.

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Mehlhorn, Heinz. "African Skin Filaria." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27769-6_3589-1.

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Mehlhorn, Heinz. "Moving Skin Filaria." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27769-6_4079-1.

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Townson, Harold. "Infection of mosquitoes with filaria." In The Molecular Biology of Insect Disease Vectors. Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-009-1535-0_9.

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Pearlman, Eric, Rajeev K. Mehlotra, Musa A. Haxhiu, and Laurie R. Hall. "Cytokine Regulation of Filaria: Induced Airway and Corneal Disease." In Biology of Parasitism. Springer US, 2000. http://dx.doi.org/10.1007/978-1-4757-4622-8_11.

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Murty, U. Suryanarayana, and Jianhong Wu. "Filaria Monitoring Visualization System: A New Dimension for Integrated Control of Lymphatic Filariasis." In Dynamic Models of Infectious Diseases. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-3961-5_7.

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Goel, Trilok Chandra, and Apul Goel. "Filarial Fever." In Lymphatic Filariasis. Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-2257-9_12.

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Conference papers on the topic "Filaria"

1

Ataev, A. M., M. M. Zubairova, N. T. Karsakov, and D. G. Kataeva. "THE EFFECT OF ENVIRONMENTAL FACTORS OF THE MOUNTAIN BELT ON THE LARVAL DEVELOPMENT OF DICTYOCAULUS FILARIA (RUD., 1809) AND MONIEZIA EXPANSA (RUD., 1810)." In THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL. VNIIP – FSC VIEV, 2024. http://dx.doi.org/10.31016/978-5-6050437-8-2.2024.25.46-51.

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In the high-altitude aspect of the mountain belt, a negative effect is observed for physical environmental factors on the development of helminth larval stages. In particular, it should be noted that there are differences between daytime and nighttime temperatures. In summer, during the day in the mountain zone, the air warms up to +25 оC, and at night the temperature drops to 0 оC and sometimes lower. Severe changes in temperature in mountains are one of the main factors affecting the development of the infective principle of helminth larval stages in external environment. We experimentally studied the effect environmental factors had on the larval development of Dictyocaulus filaria (Rud., 1809) and Moniezia expansa (Rud., 1810) in the mountain belt. At the same time, it was found that up to 46.0% of infective D. filaria larvae overwintered in external environment at an altitude of 1200 m above sea level, and respectively their survival rate in the trachea and bronchi of 3-month-old lambs with artificial infection was 34.1%. By spring, up to 39.6% of oribatid mites infected with M. expansa cysticercoids overwintered at an altitude of 1200 m above sea level, that survived in 23.3 to 30,0% in lambs, accordingly. The survival rate of M. expansa – free oribatid mites was 77.8%. The survival rate of D. filaria larvae that overwintered in external environment up to 2500 m above sea level reached 18.5%. Of infective larvae, D. filaria survived from 1 to 2.0% by spring at an altitude of 2500 m above sea level, and non-infective D. filaria larvae died, accordingly.
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Fuady, A. M., N. Nuraini, E. Soewono, H. Tasman, and A. K. Supriatna. "Modeling mass drug treatment and resistant filaria disease transmission." In 4TH INTERNATIONAL CONFERENCE ON MATHEMATICS AND NATURAL SCIENCES (ICMNS 2012): Science for Health, Food and Sustainable Energy. AIP Publishing LLC, 2014. http://dx.doi.org/10.1063/1.4868852.

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Fuady, A. M., E. Soewono, N. Nuraini, H. Tasman, and A. K. Supriatna. "A mass treatment model for endemic reduction of filaria disease with pre-testing." In THE 5TH INTERNATIONAL CONFERENCE ON RESEARCH AND EDUCATION IN MATHEMATICS: ICREM5. AIP, 2012. http://dx.doi.org/10.1063/1.4724147.

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Movsesyan, S. O., R. A. Petrosyan, M. A. Nikogosyan, et al. "BIODIVERSITY OF THE PARASITE FAUNA IN THE NORTHERN REGIONS OF ARMENIA AND THE LAKE SEVAN BASIN." In THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL. All-Russian Scientific Research Institute for Fundamental and Applied Parasitology of Animals and Plant – a branch of the Federal State Budget Scientific Institution “Federal Scientific Centre VIEV”, 2023. http://dx.doi.org/10.31016/978-5-6048555-6-0.2023.24.306-311.

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The variety of parasite species, infection of domesticated animals (including cattle,&#x0D; sheep, goats, rabbits, poultry, dogs and pigs), natural infection of biohelminths'&#x0D; intermediate hosts (including terrestrial and freshwater mollusks, soil oribatid mites)&#x0D; with helminth larvae, and the species composition of tick vectors of blood protozoan&#x0D; diseases have been studied. The studies found the infection of the above animals with&#x0D; the following helminth species: 4 trematode species Fasciola hepatica, F. gigantica,&#x0D; Dicrocoelium lanceatum, Paramphistomum sp., 13 nematode species Ascaris suum, A.&#x0D; galli, Syngamus trachea, Capillaria caudinflata, Trichuris ovis, Tr. suis, Metastrongylus&#x0D; elongatus, Chabertia sp., Haemonchus sp., Protostrongylus spp., Muellerius capillaris,&#x0D; Dictyocaulus filaria, Cystocaulus nigrescens, 2 cestode species Moniezia expansa, M.&#x0D; benedeni; 9 eimeria species Eimeria arloingi, E. intricata, E. stidae, E. magna, E.&#x0D; perforans, E. tenella, E. acervulina, and E. exigua; 3 Haemosporidia species Babesia&#x0D; bigeminum, B. ovis, and B. canis; and 1 Leishmania species Leishmania tropica.&#x0D; There were also detected 17 species of ticks, vectors of blood protozoan diseases of&#x0D; animals, and intermediate hosts of moniezia were isolated. Two species of terrestrial&#x0D; and 3 species of freshwater mollusks being as intermediate hosts of helminths were&#x0D; recorded.
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Ibrokhimzoda, B. I., M. Y. Kurchiev, K. I. Zarifzoda, et al. "MIXED INVASION IS ONE OF THE MOST COMMON MANIFESTATIONS OF PARASITISM AMONG ANIMALS." In THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL. VNIIP – FSC VIEV, 2025. https://doi.org/10.31016/978-5-6053355-1-1.2025.26.122-128.

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The article provides data on multiple invasions of young and adult animals. We identified associated infections by 3–6 nematode species (Chabertia ovіna, Bunostomum trіgonocephalum, Trіchostrongуlus ахеі, Haemonchus contortus, Nematodіrus spathіger, Dіctyocaulus filarіa) among lambs, 10–14 species (C. ovіna, Bunostomum рhlebotomum, B. trіgonocephalum, Oesophagostomum radіatum, O. venulosum, T. ахеі, T. colubriformіs, Ostertagіa ostertagі, Marshallagіа marshallі, Cooperіa oncophora, H. contortus, N. spathіger, Trichocephalus ovis, D. filarіa) in young small cattle aged 1 to 2 years, and 8–12 species (C. ovіna, B. рhlebotomum, B. trіgonocephalum, O. radіatum, T. ахеі, O. ostertagі, M. marshallі, C. oncophora, H. contortus, N. spathіger, T. ovis, D. filarіa) of in adult animals (over 3 years of age). Mixed infections by 4–7 nematode species (C. ovіna, H. contortus, N. spathіger, Neoascaris vitulorum, Thelazia rhodesi, T. skrjabini, Dіctyocaulus filarіa) were detected in calves, 6–10 species (C. ovіna, B. рhlebotomum, B. trіgonocephalum, T. ахеі, O. ostertagі, C. oncophora, H. contortus, N. spathіger, T. rhodesi, T. skrjabini) in young cattle aged 1 to 2 years, and 5–8 species (C. ovіna, B. рhlebotomum, T. ахеі, O. ostertagі, H. contortus, N. spathіger, T. rhodesi, T. skrjabini) in adult animals (over 3 years of age).
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Sano, Ryoko. "Mechanical Response of Single Filamin A (ABP-280) Molecules and Its Role in the Actin/Filamin A Gel." In SLOW DYNAMICS IN COMPLEX SYSTEMS: 3rd International Symposium on Slow Dynamics in Complex Systems. AIP, 2004. http://dx.doi.org/10.1063/1.1764155.

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Gehmlich, Katja, Sajjad Nuthay, and Sophie Broadway-Stringer. "BS22 How does filamin C sense mechanical strain?" In British Cardiovascular Society Annual Conference, ‘Back to the patient’, 3–5 June 2024. BMJ Publishing Group Ltd and British Cardiovascular Society, 2024. http://dx.doi.org/10.1136/heartjnl-2024-bcs.248.

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Caebron, J. Y., M. Joseph, H. Vorng, J. Pincemail, M. Lagaede, and A. Capron. "OXYGEN FREE RADICAL-DEPENDENT STEP IN THE CYTOTOXICITY OF DEC-TREATED PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642819.

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Over the past 35 years, diethylcarbamazine (DEC) has been the most widely used agent for the treatment of filarial diseases. However, in spite of millions of individuals treated, the mode of action of this drug remained unexplained until recently when we reported that the microfilaricidal activity of DEC was mediated by blood platelets with the additional triggering of a filarial excretory antigen (FEA) (Nature, 1987).To set up the mechanism of the larvicidal action of platelets activatedby both DEC and FEA, various inhibitors of the arachidonic acid metabolism were added in the cytotoxic assay. Aspirin failed to modify the platelet activity, whilst nordihydroguaiaretic acid, esculetin, and 5,8,11,14-heneicosatetraynoic acid dose-dependently inhibited the killing of parasites. This relationship suggested the production of a putative cytotoxic lipoxygenase product. Surprisingly, no increase in oxygenated metabolites was noted both by thin layer chromatography and by high pressure liquid chromatography.Thus, we investigated the involvement of oxygen free radicals. The hydroxyl radical scavengers tested (benzoate, uric acid, mannitol, methylene blue... ) more or less inhibited the platelet killing activity. In addition, Fe2 + (down to 10-11M) enhanced the DEC-induced cytotoxicity which was abolished in the presence of the Fe2 + chelator o-phenantroline. Finally, using the electronspin resonance technique it was possible to drop OH radicals from platelets with DMPO, but only in the presence of both DEC and FEA.These results, taken with those concerning the interaction of either IgE/anti-IgE (Nature, 1983, 303, 810-812) or CRP (Science, 1986, 231, 153-156) with platelets, should be regarded as a significant insight into the involvement of platelets in various pathological processes.
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9

Emiralioglu, Nagehan, Nural Kiper, Nicolaus Schwerk, et al. "An insight of lung cysts with filamin A mutation." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa3833.

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10

Ignatiuk, D. A., K. A. Wikenheiser-Brokamp, D. Hayes, and C. Towe. "Novel Filamin A Mutation Causing Advanced Infant Pulmonary Disease." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a3455.

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Reports on the topic "Filaria"

1

Evans, Holly. The Use of Filariae as a Therapeutic Agent for Hypersensitivity Diseases. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ad1012825.

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2

Outhouse, Amanda C., Kelsey B. Carlson, Chris A. Fedler, Elisabeth J. Huff-Lonergan, Kenneth J. Prusa, and Steven M. Lonergan. Degradation of Filamin in Aged Pork Loins Classified by High and Low Star Probe Values. Iowa State University, 2017. http://dx.doi.org/10.31274/ans_air-180814-339.

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3

Kochalski, Cezary, and Dawid Szutowski. Rentowność i płynność przedsiębiorstw w kontekście wyzwań Polskiego Ładu. Raport sektorowy. Wydawnictwo Uniwersytetu Ekonomicznego w Poznaniu, 2023. http://dx.doi.org/10.18559/978-83-8211-184-2.

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Raport składa się z trzech części. W części pierwszej wyodrębniono filary Polskiego Ładu, zidentyfikowano dla każdego z nich zmienne makroekonomiczne oraz przedstawiono kształtowanie się wielkości zmiennych makroekonomicznych w latach 2011–2020. Część drugą poświęcono rentowności polskich przedsiębiorstw w badanym okresie, koncentrując się na kształtowaniu się jej podstawowych wskaźników. W części trzeciej przedstawiono zdolność rozpatrywanych przedsiębiorstw do regulowania zobowiązań krótkoterminowych na podstawie podstawowych wskaźników statycznych płynności finansowej i zadłużenia. Wyniki przeprowadzonej analizy zamieszczono w podsumowaniu. Publikacja dofinansowana ze środków budżetu państwa w ramach programu Ministra Edukacji i Nauki pod nazwą „Nauka dla Społeczeństwa”, nr projektu NdS/543640/2021/2022, kwota dofinansowania 12 000 zł, całkowita wartość projektu 699 200 zł.
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4

Kochalski, Cezary, and Dawid Szutowski. Rentowność i płynność przedsiębiorstw w kontekście wyzwań Polskiego Ładu. Raport sektorowy. Wydawnictwo Uniwersytetu Ekonomicznego w Poznaniu, 2024. http://dx.doi.org/10.18559/978-83-8211-211-5.

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Raport (edycja druga, pierwsza była wydana w 2023 roku) składa się z trzech części. W części pierwszej wyodrębniono filary Polskiego Ładu, zidentyfikowano dla każdego z nich zmienne makroekonomiczne oraz przedstawiono kształtowanie się wielkości zmiennych makroekonomicznych w latach 2011–2021. Część drugą poświęcono rentowności polskich przedsiębiorstw w badanym okresie, koncentrując się na kształtowaniu się jej podstawowych wskaźników. W części trzeciej przedstawiono zdolność rozpatrywanych przedsiębiorstw do regulowania zobowiązań krótkoterminowych na podstawie podstawowych wskaźników statycznych płynności finansowej i zadłużenia. Wyniki przeprowadzonej analizy zamieszczono w podsumowaniu. W raporcie zamieszczono również komentarz dotyczący zmian płynności i rentowności przedsiębiorstw w okresie postpandemicznym. Metodycznie obie edycje raportu bazują na identycznych rozwiązaniach, co umożliwia porównywalność zaprezentowanych w nich wyników. Raport drugi uwzględnia szerszy zakres czasowy oraz komentarz dotyczący zmian płynności i rentowności przedsiębiorstw w okresie postpandemicznym. Publikacja dofinansowana ze środków budżetu państwa w ramach programu Ministra Edukacji i Nauki pod nazwą „Nauka dla Społeczeństwa”, nr projektu NdS/543640/2021/2022, kwota dofinansowania 12 000 zł, całkowita wartość projektu 699 200 zł.
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