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Journal articles on the topic 'FILM'S CYTOTOXICITY'

Author: Grafiati

Published: 11 September 2023

Last updated: 31 July 2025

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1

Negrila, Catalin Constantin, Daniela Predoi, Rodica V. Ghita, et al. "Multi-Level Evaluation of UV Action upon Vitamin D Enhanced, Silver Doped Hydroxyapatite Thin Films Deposited on Titanium Substrate." Coatings 11, no. 2 (2021): 120. http://dx.doi.org/10.3390/coatings11020120.

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Hydroxyapatite Ca10(PO4)6(OH)2 (HAp) is an important bioactive material for bone tissue reconstruction, due to its highly thermodynamic stability at a physiological pH without bio-resorption. In the present study, the Ag:HAp and the corresponding Ag:HAp + D3 thin films (~200 nm) coating were obtained by vacuum deposition method on Ti substrate. The obtained samples were exposed to different UV irradiation times, in order to investigate the UV light action upon thin films, before considering this method for the thin film’s decontamination. The effects of UV irradiation upon Ag:Hap + D3 are pres

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Zemek, Josef, Petr Jiricek, Jana Houdkova, Martin Ledinsky, Miroslav Jelinek, and Tomas Kocourek. "On the Origin of Reduced Cytotoxicity of Germanium-Doped Diamond-Like Carbon: Role of Top Surface Composition and Bonding." Nanomaterials 11, no. 3 (2021): 567. http://dx.doi.org/10.3390/nano11030567.

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This work attempts to understand the behaviour of Ge-induced cytotoxicity of germanium-doped hydrogen-free diamond-like carbon (DLC) films recently thoroughly studied and published by Jelinek et al. At a low doping level, the films showed no cytotoxicity, while at a higher doping level, the films were found to exhibit medium to high cytotoxicity. We demonstrate, using surface-sensitive methods—two-angle X-ray-induced core-level photoelectron spectroscopy (ARXPS) and Low Energy Ion Scattering (LEIS) spectroscopy, that at a low doping level, the layers are capped by a carbon film which impedes t

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3

Rodil, S. E., R. Olivares, and H. Arzate. "In vitro cytotoxicity of amorphous carbon films." Bio-Medical Materials and Engineering 15, no. 1-2 (2005): 101–12. https://doi.org/10.1177/0959298920050151-2011.

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Amorphous carbon (a‐C), carbon nitride (a‐CN) and titanium films were deposited on stainless steel substrates (SS) using a dc magnetron sputtering system attached to a high vacuum chamber. Films were deposited using a base pressure of 1.3×10 −4 Pa. For the carbon films a pure graphite target was eroded in an Argon plasma. For the case of the a‐CN films, the Ar flux was substituted by 100% N 2 gas. Titanium films were deposited in a different chamber, using a pure Ti target and an argon plasma. In vitro studies were carried out on the coated samples using human osteoblasts cells. Cytotoxicity o

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4

Xie, Rui Juan, Ming Zhong Li, Shen Zhou Lu, Wei Hua Sheng, and Yu Feng Xie. "Preparation of Sericin Film and its Cytocompatibility." Key Engineering Materials 342-343 (July 2007): 241–44. http://dx.doi.org/10.4028/www.scientific.net/kem.342-343.241.

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Bombyx mori Sericin films were prepared with PEG-DE as cross linking agent. The main physical properties, structure characteristics, cytotoxicity and cell proliferation of sericin films were measured and analyzed. The result showed that sericin films prepared by cast method containing 30-40% of PEG-DE, showed good mechanical properties. PEG-DE caused the changes of the condensed structure of sericin films. The films prepared from sericin extracted both from silk-gland and cocoon shell showed good cytocompatibility. Silk sericin films with PEG-DE had no obvious cytotoxicity to cells.

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Puccetti, Matteo, Anna Donnadio, Maurizio Ricci, et al. "Alginate Ag/AgCl Nanoparticles Composite Films for Wound Dressings with Antibiofilm and Antimicrobial Activities." Journal of Functional Biomaterials 14, no. 2 (2023): 84. http://dx.doi.org/10.3390/jfb14020084.

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Recently, silver-based nanoparticles have been proposed as components of wound dressings due to their antimicrobial activity. Unfortunately, they are cytotoxic for keratinocytes and fibroblasts, and this limits their use. Less consideration has been given to the use of AgCl nanoparticles in wound dressings. In this paper, a sustainable preparation of alginate AgCl nanoparticles composite films by simultaneous alginate gelation and AgCl nanoparticle formation in the presence of CaCl2 solution is proposed with the aim of obtaining films with antimicrobial and antibiofilm activities and low cytot

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Rakmae, Suriyan, and Nitinat Suppakarn. "Thermal Properties, Biodegradability and Cytotoxicity of PLA/Sericin Films." Advanced Materials Research 410 (November 2011): 86–89. http://dx.doi.org/10.4028/www.scientific.net/amr.410.86.

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In this study, PLA/sericin films at various contents of sericin were prepared. Thermal properties, in vitro degradability and in vitro cytotoxicity of the films were characterized. The results illustrated that the incorporation of sericin into PLA matrix crucially affected thermal properties and biodegradability of the films and also enhanced human fibroblast cells attachment and proliferation on the film surface.

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Pamlényi, Krisztián, Géza Regdon, Dániel Nemes, Ferenc Fenyvesi, Ildikó Bácskay, and Katalin Kristó. "Stability, Permeability and Cytotoxicity of Buccal Films in Allergy Treatment." Pharmaceutics 14, no. 8 (2022): 1633. http://dx.doi.org/10.3390/pharmaceutics14081633.

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Oral mucoadhesive systems, such as polymer films, are among innovative pharmaceutical products. These systems can be applied in swallowing problems and can also be used in geriatrics and paediatrics. In our earlier work, we successfully formulated buccal mucoadhesive polymer films, which contained cetirizine-hydrochloride (CTZ) as the API. The present study focused on investigating the stability and permeability of the prepared films. The stability of the films was studied with an accelerated stability test. During the stability test, thickness, breaking hardness and in vitro mucoadhesivity we

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8

Hissae Yassue-Cordeiro, Zandonai, Pereira Genesi, et al. "Development of Chitosan/Silver Sulfadiazine/Zeolite Composite Films for Wound Dressing." Pharmaceutics 11, no. 10 (2019): 535. http://dx.doi.org/10.3390/pharmaceutics11100535.

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Biopolymeric films with silver sulfadiazine (AgSD) are proposed as an alternative to the occlusive AgSD-containing creams and gauzes, which are commonly used in the treatment of conventional burns. While the recognized cytotoxicity of AgSD has been reported to compromise its use as an antimicrobial drug in pharmaceuticals, this limitation can be overcome by developing sustained-release formulations. Microporous materials as zeolites can be used as drug delivery systems for sustained release of AgSD. The purpose of this work was the development and characterization of chitosan/zeolite composite

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9

Almeida, Nilsa Maria Galvão, Renata Lima, Thaís Francine Ribeiro Alves, Márcia de Araújo Rebelo, Patrícia Severino, and Marco Vinícius Chaud. "A novel dosage form for buccal administration of bupropion." Brazilian Journal of Pharmaceutical Sciences 51, no. 1 (2015): 91–100. http://dx.doi.org/10.1590/s1984-82502015000100010.

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Bupropion is an antidepressant used in the treatment of smoking. The purpose of this study was to prepare controlled-release hydrogel films for buccal administration of bupropion and investigate its physicochemical and cytotoxic properties. The films were prepared from ultrapure sodium carboxymethylcellulose, hydroxypropylmethylcellulose K4M, and medium-viscosity chitosan. Evaluation of film physicochemical characteristics was based on scanning electron microscopy, bupropion content, mechanical strength (burst strength, relaxation, resilience, and traction), and cytotoxicity. Bupropion content

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10

Sathya Seeli, David, Abinash Das, and Mani Prabaharan. "Zinc Oxide–Incorporated Chitosan–Poly(methacrylic Acid) Polyelectrolyte Complex as a Wound Healing Material." Journal of Functional Biomaterials 14, no. 4 (2023): 228. http://dx.doi.org/10.3390/jfb14040228.

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A novel type of porous films based on the ZnO-incorporated chitosan–poly(methacrylic acid) polyelectrolyte complex was developed as a wound healing material. The structure of porous films was established by Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and energy dispersive X-ray (EDX) analysis. Scanning electron microscope (SEM) and porosity studies revealed that the pore size and porosity of the developed films increased with the increase in zinc oxide (ZnO) concentration. The porous films with maximum ZnO content exhibited improved water swelling degree (1400%), c

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11

Connor, Lydia M., Carol A. Ballinger, Thomas B. Albrecht, and Edward M. Postlethwait. "Interfacial phospholipids inhibit ozone-reactive absorption-mediated cytotoxicity in vitro." American Journal of Physiology-Lung Cellular and Molecular Physiology 286, no. 6 (2004): L1169—L1178. http://dx.doi.org/10.1152/ajplung.00397.2003.

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The intrapulmonary distribution of inhaled ozone (O3) and induction of site-specific cell injury are related to complex interactions among airflow patterns, local gas-phase concentrations, and the rates of O3 flux into, and reaction and diffusion within, the epithelial lining fluid (ELF). Recent studies demonstrated that interfacial phospholipid films appreciably inhibited NO2 absorption. Because surface-active phospholipids are present on alveolar and airway interfaces, we investigated the effects of interfacial films on O3-reactive absorption and acute cell injury. Compressed films of dipalm

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12

Buinov, Aleksandr S., Elvira R. Gafarova, Ekaterina A. Grebenik, et al. "Fabrication of Conductive Tissue Engineering Nanocomposite Films Based on Chitosan and Surfactant-Stabilized Graphene Dispersions." Polymers 14, no. 18 (2022): 3792. http://dx.doi.org/10.3390/polym14183792.

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Chitosan (CS)/graphene nanocomposite films with tunable biomechanics, electroconductivity and biocompatibility using polyvinylpyrrolidone (PVP) and Pluronic F108 (Plu) as emulsion stabilizers for the purpose of conductive tissue engineering were successfully obtained. In order to obtain a composite solution, aqueous dispersions of multilayered graphene stabilized with Plu/PVP were supplied with CS at a ratio of CS to stabilizers of 2:1, respectively. Electroconductive films were obtained by the solution casting method. The electrical conductivity, mechanical properties and in vitro and in vivo

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13

Jelinek, Miroslav, Tomáš Kocourek, Karel Jurek, et al. "Preliminary Study of Ge-DLC Nanocomposite Biomaterials Prepared by Laser Codeposition." Nanomaterials 9, no. 3 (2019): 451. http://dx.doi.org/10.3390/nano9030451.

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This paper deals with the synthesis and study of the properties of germanium-doped diamond-like carbon (DLC) films. For deposition of doped DLC films, hybrid laser technology was used. Using two deposition lasers, it was possible to arrange the dopant concentrations by varying the laser repetition rate. Doped films of Ge concentrations from 0 at.% to 12 at.% were prepared on Si (100) and fused silica (FS) substrates at room temperature. Film properties, such as growth rate, roughness, scanning electron microscopy (SEM) morphology, wavelength dependent X-ray spectroscopy (WDS) composition, VIS-

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14

Savaris, Michele, Gustavo L. Braga, Venina dos Santos, et al. "Biocompatibility Assessment of Poly(lactic acid) Films after Sterilization with Ethylene Oxide in Histological Study In Vivo with Wistar Rats and Cellular Adhesion of Fibroblasts In Vitro." International Journal of Polymer Science 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/7158650.

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Biomaterials must meet certain fundamental requirements for their usage in living beings, such as biocompatibility, bifunctionality, and sterilizability, without having chemical and structural changes. The biocompatibility of poly(lactic acid) (PLA) films, shaped by compression, was evaluated after sterilization by ethylene oxide by a histological in vivo test with Wistar rats and cytotoxicity in cell adhesion in vitro. The cytotoxicity test was performed by the reduction of tetrazolium salt (MTT). Thermal and chemical changes in PLA films concerning the proposed sterilization process and char

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15

Eulálio, Hugo Yves C., Mariana Vieira, Thiago B. Fideles, et al. "Physicochemical Properties and Cell Viability of Shrimp Chitosan Films as Affected by Film Casting Solvents. I-Potential Use as Wound Dressing." Materials 13, no. 21 (2020): 5005. http://dx.doi.org/10.3390/ma13215005.

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Chitosan solubility in aqueous organic acids has been widely investigated. However, most of the previous works have been done with plasticized chitosan films and using acetic acid as the film casting solvent. In addition, the properties of these films varied among studies, since they are influenced by different factors such as the chitin source used to produce chitosan, the processing variables involved in the conversion of chitin into chitosan, chitosan properties, types of acids used to dissolve chitosan, types and amounts of plasticizers and the film preparation method. Therefore, this work

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16

Ghafouri Azar, Mina, Lucie Wiesnerova, Jana Dvorakova, et al. "Optimizing PCL/PLGA Scaffold Biocompatibility Using Gelatin from Bovine, Porcine, and Fish Origin." Gels 9, no. 11 (2023): 900. http://dx.doi.org/10.3390/gels9110900.

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This research introduces a novel approach by incorporating various types of gelatins, including bovine, porcine, and fish skin, into polycaprolactone and poly (lactic-co-glycolic acid) using a solvent casting method. The films are evaluated for morphology, mechanical properties, thermal stability, biodegradability, hemocompatibility, cell adhesion, proliferation, and cytotoxicity. The results show that the incorporation of gelatins into the films alters their mechanical properties, with a decrease in tensile strength but an increase in elongation at break. This indicates that the films become

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17

Jeong, Heeseok, Jeongwon Rho, Ji-Yeon Shin, Deuk Yong Lee, Taeseon Hwang, and Kwang J. Kim. "Mechanical properties and cytotoxicity of PLA/PCL films." Biomedical Engineering Letters 8, no. 3 (2018): 267–72. http://dx.doi.org/10.1007/s13534-018-0065-4.

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18

Kędzierska, Marta, Sara Blilid, Katarzyna Miłowska, et al. "Insight into Factors Influencing Wound Healing Using Phosphorylated Cellulose-Filled-Chitosan Nanocomposite Films." International Journal of Molecular Sciences 22, no. 21 (2021): 11386. http://dx.doi.org/10.3390/ijms222111386.

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Marine polysaccharides are believed to be promising wound-dressing nanomaterials because of their biocompatibility, antibacterial and hemostatic activity, and ability to easily shape into transparent films, hydrogels, and porous foams that can provide a moist micro-environment and adsorb exudates. Current efforts are firmly focused on the preparation of novel polysaccharide-derived nanomaterials functionalized with chemical objects to meet the mechanical and biological requirements of ideal wound healing systems. In this contribution, we investigated the characteristics of six different cellul

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19

Zhang, Bowei, Hongwei Ni, Rongsheng Chen, et al. "Cytotoxicity effects of three-dimensional graphene in NIH-3T3 fibroblasts." RSC Advances 6, no. 51 (2016): 45093–102. http://dx.doi.org/10.1039/c6ra04018g.

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We present an evaluation of the in vitro cytotoxicity of 3D graphene sheets fabricated by carbonization of polydopamine (PDA) films on a template of aligned nanopore arrays (NPAs) on a stainless steel surface.

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20

Ozeki, K., and Y. Nakajima. "Antibacterial effect of Ag-containing hydroxyapatite thin film fabricated by sputtering." Bio-Medical Materials and Engineering 35, no. 1 (2024): 87–98. http://dx.doi.org/10.3233/bme-230131.

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BACKGROUND: Infections related to joint prosthesis are still a major concern for orthopedic surgeons. Hydroxyapatite (HA) is a useful biocompatible material because of its good osteocompatibility. Antibacterial HA coatings have been fabricated with addition of antibacterial agents such as Ag to HA using the plasma spraying method. However, the plasma-sprayed HA coating suffers from fractures at large thicknesses. The sputter-coated HA thin film has a high density, and has been applied clinically for dental implants. However, there are no extensive studies on Ag-containing HA thin films. OBJECT

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21

Jongwannasiri, Chavin, Nutthanun Moolsradoo, Anak Khantachawana, Pongpan Kaewtatip, and Shuichi Watanabe. "The Comparison of Biocompatibility Properties between Ti Alloys and Fluorinated Diamond-Like Carbon Films." Advances in Materials Science and Engineering 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/724126.

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Titanium and titanium alloys have found several applications in the biomedical field due to their unique biocompatibility. However, there are problems associated with these materials in applications in which there is direct contact with blood, for instance, thrombogenesis and protein adsorption. Surface modification is one of the effective methods used to improve the performance of Ti and Ti alloys in these circumstances. In this study, fluorinated diamond-like carbon (F-DLC) films are chosen to take into account the biocompatible properties compared with Ti alloys. F-DLC films were prepared o

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22

Donnadio, Anna, Valeria Ambrogi, Donatella Pietrella, Monica Pica, Giulia Sorrentino, and Mario Casciola. "Carboxymethylcellulose films containing chlorhexidine–zirconium phosphate nanoparticles: antibiofilm activity and cytotoxicity." RSC Advances 6, no. 52 (2016): 46249–57. http://dx.doi.org/10.1039/c6ra04151e.

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23

Rezvova, Maria A., Arseniy E. Yuzhalin, Tatiana V. Glushkova, et al. "Biocompatible Nanocomposites Based on Poly(styrene-block-isobutylene-block-styrene) and Carbon Nanotubes for Biomedical Application." Polymers 12, no. 9 (2020): 2158. http://dx.doi.org/10.3390/polym12092158.

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In this study, we incorporated carbon nanotubes (CNTs) into poly(styrene-block-isobutylene-block-styrene) (SIBS) to investigate the physical characteristics of the resulting nanocomposite and its cytotoxicity to endothelial cells. CNTs were dispersed in chloroform using sonication following the addition of a SIBS solution at different ratios. The resultant nanocomposite films were analyzed by X-ray microtomography, optical and scanning electron microscopy; tensile strength was examined by uniaxial tension testing; hydrophobicity was evaluated using a sessile drop technique; for cytotoxicity an

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Ozeki, K., Hideyuki Aoki, and Y. Fukui. "Crystallization of Sputtered Hydroxyapatite Films by Hydrothermal Technique and Its Cytotoxicity." Key Engineering Materials 284-286 (April 2005): 195–98. http://dx.doi.org/10.4028/www.scientific.net/kem.284-286.195.

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Hydroxyapatite (HA) was coated onto titanium substrates using radio frequency sputtering, and the coated HA films were crystallized in an autoclave at 110 °C using a low temperature hydrothermal method. The crystallinity, the Ca/P ratio, and the surface of the films were observed using XRD, EDS, and SEM, respectively. From the XRD patterns, a sputtered film after the hydrothermal treatment had crystallized after 24 h, and the Ca/P ratio decreased from 2.43 ± 0.07 to 1.75 ± 0.11. The growth rate of osteoblast cells was used for cell culture. Among control, titanium and hydrothermally treated fi

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Lou, Jia, Beibei Ren, Jie Zhang, Hao He, Zonglong Gao, and Wei Xu. "Evaluation of Biocompatibility of 316 L Stainless Steels Coated with TiN, TiCN, and Ti-DLC Films." Coatings 12, no. 8 (2022): 1073. http://dx.doi.org/10.3390/coatings12081073.

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In this study, TiN, TiCN, and Ti-diamond-like carbon (Ti-DLC) films were coated on 316 L stainless steel (AISI 316 L) substrate surface by physical vapor deposition. The biocompatibility of the three films (TiN, TiCN, and Ti-DLC) and three metals (AISI 316 L, Ti, and Cu) was compared on the basis of the differences in the surface morphology, water contact angle measurements, CCK-8 experiment results, and flow cytometry test findings. The biocompatibility of the TiN and TiCN films is similar to that of AISI 316 L, which has good biocompatibility. However, the biocompatibility of the Ti-DLC film

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Zhang, Jingjing, Wenqiang Tan, Qing Li, Xiaorui Liu, and Zhanyong Guo. "Preparation of Cross-linked Chitosan Quaternary Ammonium Salt Hydrogel Films Loading Drug of Gentamicin Sulfate for Antibacterial Wound Dressing." Marine Drugs 19, no. 9 (2021): 479. http://dx.doi.org/10.3390/md19090479.

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Hydrogels, possessing high biocompatibility and adaptability to biological tissue, show great usability in medical applications. In this research, a series of novel cross-linked chitosan quaternary ammonium salt loading with gentamicin sulfate (CTMCSG) hydrogel films with different cross-linking degrees were successfully obtained by the reaction of chitosan quaternary ammonium salt (TMCS) and epichlorohydrin. Fourier transform infrared spectroscopy (FTIR), thermal analysis, and scanning electron microscope (SEM) were used to characterize the chemical structure and surface morphology of CTMCSG

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27

Recco, M. S., A. C. Floriano, D. B. Tada, A. P. Lemes, R. Lang, and F. H. Cristovan. "Poly(3-hydroxybutyrate-co-valerate)/poly(3-thiophene ethyl acetate) blends as a electroactive biomaterial substrate for tissue engineering application." RSC Advances 6, no. 30 (2016): 25330–38. http://dx.doi.org/10.1039/c5ra26747a.

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Polyblend films based on poly(3-hydroxybutirate-co-valerate) and poly(3-thiophene ethyl acetate) – PHBV/PTAcEt showed low cytotoxicity, good adhesion and mammalian cell proliferation. The physical–chemical properties were explored.

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Kania, Aneta, Piotr Nolbrzak, Adrian Radoń, Aleksandra Niemiec-Cyganek, and Rafał Babilas. "Effect of the Thickness of TiO2 Films on the Structure and Corrosion Behavior of Mg-Based Alloys." Materials 13, no. 5 (2020): 1065. http://dx.doi.org/10.3390/ma13051065.

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This article discusses the influence of the thickness of TiO2 films deposited onto MgCa2Zn1 and MgCa2Zn1Gd3 alloys on their structure, corrosion behavior, and cytotoxicity. TiO2 layers (about 200 and 400 nm thick) were applied using magnetron sputtering, which provides strong substrate adhesion. Such titanium dioxide films have many attractive properties, such as high corrosion resistance and biocompatibility. These oxide coatings stimulate osteoblast adhesion and proliferation compared to alloys without the protective films. Microscopic observations show that the TiO2 surface morphology is ho

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Henriques, Mariana, Maria Susano, Isabel Carvalho, Isabel Ferreri, Sandra Carvalho, and R. Oliveira. "Biological Properties of Ti-Si-C-O-N Thin Films." Journal of Nano Research 6 (June 2009): 99–114. http://dx.doi.org/10.4028/www.scientific.net/jnanor.6.99.

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The main aim of this work was to study the feasibility of new coatings for medical devices. Ti-Si-C-O-N films were deposited by DC unbalanced reactive magnetron sputtering, using different oxygen and nitrogen partial pressure ratios (pO2/pN2). Surface properties were also analysed. Staphylococcus epidermidis was used to study biofilm formation and cytotoxicity was determined using fibroblasts. Surface morphology changed with the increase of pO2/pN2. Samples of high hydrophobicity displayed opposite behaviour in terms of biofilm formation, presenting the highest and lowest biomass. Moreover, th

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F. B. de O. Correia, Rebeca, Aline G. Sampaio, Noala V. M. Milhan, et al. "Zn:DLC films via PECVD-HIPIMS: Evaluation of antimicrobial activity and cytotoxicity to mammalian cells." Journal of Vacuum Science & Technology A 41, no. 3 (2023): 033103. http://dx.doi.org/10.1116/6.0002354.

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DLC films were grown with Zn via a combined plasma-enhanced chemical vapor deposition (PECVD) and high-power impulse magnetron sputtering (HIPIMS) process. The films were deposited on textiles in an atmosphere of Ar and C2H2, and the percentage of metal in the DLC was varied by controlling the acetylene gas flow. At first, to evaluate the antimicrobial activity, a screening test with the ISO 22196 standard was carried out. Afterward, AATCC TM100:2019 was used to evaluate the antimicrobial effectiveness of the films on textiles. The antimicrobial effectiveness of the coating was studied against

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Sunthornpan, Narin, Shuichi Watanabe, and Nutthanun Moolsradoo. "Elements-Added Diamond-Like Carbon Film for Biomedical Applications." Advances in Materials Science and Engineering 2019 (March 3, 2019): 1–11. http://dx.doi.org/10.1155/2019/6812092.

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Elements-added diamond-like carbon films for biomedical applications were investigated. The aim of this work was to study the effects of the elemental contents (silicon and silicon-nitrogen) in a DLC film on its properties for biomedical applications. Pure DLC, Si-DLC, and Si-N-DLC films were prepared from C2H2, C2H2 : TMS, and C2H2 : TMS : N2 gaseous mixtures, deposited on an AISI 316L substrate using the plasma-based ion implantation (PBII) technique. The structure of films was analyzed using Raman spectroscopy. The chemical composition of films was measured using energy dispersive X-ray spe

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Abalymov, A. A., F. S. Fedorov, F. S. Fedorov, D. A. Gorin, and A. G. Nasibulin. "PROMISING ELECTRICALLY CONDUCTIVE CARBON NANOTUBE SUBSTRATES FOR CELL GROWTH MONITORING." BIOTECHNOLOGY: STATE OF THE ART AND PERSPECTIVES 1, no. 2022-20 (2022): 68–70. http://dx.doi.org/10.37747/2312-640x-2022-20-68-70.

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Carbon nanotube (CNT) films were tested for cytotoxicity and biocompatibility on Neuro-2A cells. Parameters such as survival, mortality and cell morphology were evaluated. The tests for the material sensitivity to a direct contact with cells were carried out.

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Wang, Yiyu, Xinyu Wang, Jian Shi, Rong Zhu, Junhua Zhang, and Zongrui Zhang. "Flexible silk fibroin films modified by genipin and glycerol." RSC Advances 5, no. 123 (2015): 101362–69. http://dx.doi.org/10.1039/c5ra19754f.

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Rangel, Elidiane C., Eduardo S. de Souza, Francine S. de Moraes, et al. "Cell Adhesion to Plasma-Coated PVC." Scientific World Journal 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/132308.

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To produce environments suitable for cell culture, thin polymer films were deposited onto commercial PVC plates from radiofrequency acetylene-argon plasmas. The proportion of argon in the plasmas, PAr, was varied from 5.3 to 65.8%. The adhesion and growth of Vero cells on the coated surfaces were examined for different incubation times. Cytotoxicity tests were performed using spectroscopic methods. Carbon, O, and N were detected in all the samples using XPS. Roughness remained almost unchanged in the samples prepared with 5.3 and 28.9% but tended to increase for the films deposited with PArbet

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Saied, M. A., and K. N. Abdel Nour. "Preparation and characterization of PMMA/ZnO nanocomposites for antistatic and biomedical applications." Advances in Natural Sciences: Nanoscience and Nanotechnology 14, no. 3 (2023): 035005. http://dx.doi.org/10.1088/2043-6262/ace711.

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Abstract Polymethyl methacrylate (PMMA)/Palm oil/ZnO nanocomposite films of concentrations 0, 0.5, 1, 2, 5, 10, and 15 wt% were prepared by solution casting technique. Tween 80 was used as a surfactant. The prepared films were characterised by different techniques in addition to antimicrobial and cytotoxicity tests. The scanning electron microscope (SEM) micrographs of fractured surfaces of the films showed that palm oil (PO) and Tween 80 enhanced ZnO NPs dispersion. An excess ZnO loading led to polymer saturation with ZnO NPs which accumulate on PMMA surface. X-ray diffraction (XRD) measureme

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Jorge, Hernando Bautista-Ruiz, Jairo Olaya-Flórez Jhon, and Arnulfo Aperador-Chaparro Willian. "Biocompatibility of bismuth silicate coatings deposited on 316L stainless steel by sol-gel process." Revista Facultad de Ingeniería –redin-, no. 84 (September 25, 2017): 27–34. https://doi.org/10.17533/udea.redin.n84a04.

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Bismuth silicate, (BSO) thin films have been fabricated by sol–gel process. The stable sol was synthesized by using bismuth nitrate (III) pentahydrate and tetraethyl orthosilicate (TEOS). The films were deposited by spin-coating at 1500 rpm on Stainless Steel 316L. The films were characterized by Atomic Force Microscopy (AFM), Scanning Electron Microscopy (SEM), X-ray diffraction (XRD) besides the measured of the films thickness. This study aimed to evaluate the cell adhesion and cellular proliferation of osteoblast cells on BSO thin films and substrate 316L by MTT assay. It is concluded

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Altınay, Ezgi, Fatma Zehra Köse, Sezen Canım Ateş, and Kadriye Kızılbey. "Ibuprofen-Loaded Silver Nanoparticle-Doped PVA Gels: Green Synthesis, In Vitro Cytotoxicity, and Antibacterial Analyses." Gels 10, no. 2 (2024): 143. http://dx.doi.org/10.3390/gels10020143.

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In contrast to conventional drug delivery systems, controlled drug release systems employ distinct methodologies. These systems facilitate the release of active substances in predetermined quantities and for specified durations. Polymer hydrogels have gained prominence in controlled drug delivery because of their unique swelling–shrinkage behavior and ability to regulate drug release. In this investigation, films with a hydrogel structure were crafted using polyvinyl alcohol, a biocompatible polymer, and silver nanoparticles. Following characterization, ibuprofen was loaded into the hydrogels

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Luangbudnark, Witoo, Jarupa Viyoch, Wiroon Laupattarakasem, Palakorn Surakunprapha, and Pisamai Laupattarakasem. "Properties and Biocompatibility of Chitosan and Silk Fibroin Blend Films for Application in Skin Tissue Engineering." Scientific World Journal 2012 (2012): 1–10. http://dx.doi.org/10.1100/2012/697201.

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Chitosan/silk fibroin (CS/SF) blend films were prepared and evaluated for feasibility of using the films as biomaterial for skin tissue engineering application. Fourier transform infrared spectroscopy and differential scanning calorimetry analysis indicated chemical interaction between chitosan and fibroin. Chitosan enhancedβ-sheet conformation of fibroin and resulted in shifting of thermal degradation of the films. Flexibility, swelling index, and enzyme degradation were also increased by the chitosan content of the blend films. Biocompatibility of the blend films was determined by cultivatio

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Zhang, Xiaojuan, Wenbin Cai, Lingyun Hao, and Wei Zhang. "In Situ Preparation and Properties of Poly(vinyl alcohol)/Carboxymethyl Chitosan/Cyanidin Hydrogel Films." Journal of Nanomaterials 2019 (March 27, 2019): 1–8. http://dx.doi.org/10.1155/2019/7510573.

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This study synthesized poly(vinyl alcohol)/carboxymethyl chitosan/cyanidin (PVA/CMCS/CY) hydrogel films. First, PVA and CMCS were used to synthesize hydrogel films by ultraviolet irradiation. Meanwhile, CY was in situ combined into the hydrogel films through the electrostatic attraction between CMCS and CY. Next, the products were analyzed using Fourier-transform infrared spectroscopy, scanning electron microscopy, contact angle test, swelling analysis, and mechanical property test. The results revealed that compared with PVA/CMCS hydrogel films, the PVA/CMCS/CY hydrogel films had an interporo

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Wang, Hua-Jie, Yuan-Yuan Sun, Ying Cao, Xue-Hong Yu, Xiao-Min Ji, and Lin Yang. "Porous zinc oxide films: Controlled synthesis, cytotoxicity and photocatalytic activity." Chemical Engineering Journal 178 (December 2011): 8–14. http://dx.doi.org/10.1016/j.cej.2011.09.088.

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Mzyk, A., R. Major, J. M. Lackner, F. Bruckert, and B. Major. "Cytotoxicity control of SiC nanoparticles introduced into polyelectrolyte multilayer films." RSC Adv. 4, no. 60 (2014): 31948–54. http://dx.doi.org/10.1039/c4ra03914a.

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Martins, Valter F. R., Ana I. Lopes, Manuela Machado, et al. "Biodegradable Films with Polysaccharides, Proteins, and Bioactive Compounds from Lobosphaera sp.: Antioxidant and Antimicrobial Activities." Foods 14, no. 8 (2025): 1327. https://doi.org/10.3390/foods14081327.

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Microalgae are a sustainable source of bioactive compounds and nutrients that do not compete with crops for arable land. Lobosphaera sp. was used to produce biodegradable films. Bioactive compounds, polysaccharides, and proteins were extracted from this microalga. The total phenolic content (TPC) and antioxidant activity (ABTS, DPPH, and ORAC) of the bioactive-rich extract were determined, and its composition was analyzed for phenolics using LC-ESI-QqTOF-HRMS and for lipids using GC-FID. The cytotoxicity of this extract on Caco-2 cells was also assessed. Different types of films were produced

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Reznickova, Alena, Veronika Lacmanova, Kalbacova Marie Hubalek, et al. "As-deposited and dewetted Cu layers on plasma treated glass: adhesion study and its effect on biological response." Applied Surface Science Advances 24 (September 18, 2024): 100639. https://doi.org/10.1016/j.apsadv.2024.100639.

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Improving the adhesion of nanosized copper films to a glass substrate is vital for their application in electronics and medicine, as it enhances their overall reliability. For this purpose, we employed Ar plasma etching (240 s) and magnetron sputtering to create copper layers on a glass substrate. Furthermore, we investigated the effect of subsequent solid state dewetting (at 300 °C) of Cu nanolayers on the interface stability. Increasing the sputtering time resulted in elevated copper concentration, UV-Vis absorption, conductivity, and surface roughness. The as-deposited and dewetted samp

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Naumenko, K. S., A. I. Ievtushenko, V. A. Karpyna, O. I. Bykov, and L. A. Myroniuk. "The Effect of Ag-Doping on the Cytotoxicity of ZnO Nanostructures Grown on Ag/Si Substrates by APMOCVD." Mikrobiolohichnyi Zhurnal 84, no. 2 (2022): 47–56. http://dx.doi.org/10.15407/microbiolj84.02.047.

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The search and development of new nanostructures and nanomaterials are very important for the progress of nanotechnology and modern microbiology. Due to the unique properties of silver and zinc oxide, these nanoparticles are the optimal basis for creating nanostructures with potential antiviral activity. An important issue in these studies is the establishment of cytotoxicity of these nanoparticles and their composites. Aim. To define the influence of substrate temperature and Ag concentration in ZnO lattice on the microstructure and cytotoxicity of zinc oxide nanostructures. Methods. Pure and

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Popovici, Violeta, Elena Matei, Georgeta Camelia Cozaru, et al. "Evaluation of Usnea barbata (L.) Weber ex F.H. Wigg Extract in Canola Oil Loaded in Bioadhesive Oral Films for Potential Applications in Oral Cavity Infections and Malignancy." Antioxidants 11, no. 8 (2022): 1601. http://dx.doi.org/10.3390/antiox11081601.

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Usnea lichens are known for their beneficial pharmacological effects with potential applications in oral medicine. This study aims to investigate the extract of Usnea barbata (L.) Weber ex F.H. Wigg from the Călimani Mountains in canola oil as an oral pharmaceutical formulation. In the present work, bioadhesive oral films (F-UBO) with U. barbata extract in canola oil (UBO) were formulated, characterized, and evaluated, evidencing their pharmacological potential. The UBO-loaded films were analyzed using standard methods regarding physicochemical and pharmacotechnical characteristics to verify t

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Doğan, E. E., P. Tokcan, M. E. Diken, B. Yilmaz, B. K. Kizilduman, and P. Sabaz. "Synthesis, Characterization and Some Biological Properties of PVA/PVP/PN Hydrogel Nanocomposites: Antibacterial and Biocompatibility." Advances in Materials Science 19, no. 3 (2019): 32–45. http://dx.doi.org/10.2478/adms-2019-0015.

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AbstractIn this study, it was aimed to synthesize hydrogel based antibacterial, biocompatible and non-toxic wound dressing materials by solvent removal method usingpoly(vinylalcohol) (PVA), poly(vinylpyrolidone) (PVP) and nano pomegranate seed (PN).The morphology, swelling capacity, contact angle, antibacterial activity, biocompatibility and cytotoxicity of the synthesized films were determined. From the experimental findings, it was found that the PN particles were nano-sized, showed homogeneous and spherical distribution and improved the hydrophobic properties of the materials obtained by th

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Kobayashi, Takaomi, Karla L. Tovar-Carrillo, Kazuki Nakasone, and Motohiro Tagaya. "Biopolymer Hydrogels Regenerated From Agave Tequilana Waste For Cytocompatable Materials." MRS Proceedings 1613 (2014): 75–82. http://dx.doi.org/10.1557/opl.2014.161.

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ABSTRACTAgave fibers were used to elaborate a transparent and flexible cellulose hydrogel films used as scaffold for tissue regeneration and tested by in vitro assays with NIH 3T3 fibroblast cells. Using dimethylacetamide/lithium chloride (DMAc/LiCl) system was possible to obtain cellulose solutions and hydrogel films were prepared by phase inverse method without cross-linker. The concentration of LiCl in the DMAc solution was varied from 4 to 12 wt% in the phase inversion process and then the cytotoxicity was tested for 14 days on the cultivation. The resultant hydrogel films showed better cy

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Rodrigues, L. R., C. G. B. T. Dias, H. J. Ceragioli, A. C. D. Rodas, F. J. M. Monteiro, and Cecília A. C. Zavaglia. "FTIR Analysis and Cytotoxicity Test of Titanium Dioxide Nanoparticles." Key Engineering Materials 493-494 (October 2011): 768–74. http://dx.doi.org/10.4028/www.scientific.net/kem.493-494.768.

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Titanium dioxide is a material widely used in electronics industry and little explored in the biomedical area, which is the objective of this work. Nowadays one can find surgical instruments coated with thin films that have bactericidal properties when they are activated in the presence of ultraviolet light. For crystalline phase control TiO2was calcinated at 500°C. The crystallite mean size for sample calcinated at 500°C was 27nm. With the results of cytotoxicity it is possible to say that biomedical applications are possible. Electron microscopy images showed nanoparticles obtained by sol-ge

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Supanakorn, Goragot, Siriporn Taokaew, and Muenduen Phisalaphong. "Multifunctional Cellulosic Natural Rubber and Silver Nanoparticle Films with Superior Chemical Resistance and Antibacterial Properties." Nanomaterials 13, no. 3 (2023): 521. http://dx.doi.org/10.3390/nano13030521.

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Composite films of natural rubber/cellulose fiber/silver nanoparticle were synthesized in a green route via the latex solution process. Hybrid cellulose filler containing carboxymethyl cellulose and cellulose microfibers was used to facilitate facile and fast preparation and to improve mechanical strength to the composites, respectively. All the composites possessed a high tensile strength of ~120 MPa, a high heat resistance of nearly 300 °C, and more than 20% biodegradability in soil in two weeks. Chemical resistance and antibacterial activity of the composite was enhanced depending on sizes

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Łopusiewicz, Łukasz, Emilia Drozłowska, Paulina Trocer, et al. "Whey Protein Concentrate/Isolate Biofunctional Films Modified with Melanin from Watermelon (Citrullus lanatus) Seeds." Materials 13, no. 17 (2020): 3876. http://dx.doi.org/10.3390/ma13173876.

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Valorization of food industry waste and plant residues represents an attractive path towards obtaining biodegradable materials and achieving “zero waste” goals. Here, melanin was isolated from watermelon (Citrullus lanatus) seeds and used as a modifier for whey protein concentrate and isolate films (WPC and WPI) at two concentrations (0.1% and 0.5%). The modification with melanin enhanced the ultraviolet (UV) blocking, water vapor barrier, swelling, and mechanical properties of the WPC/WPI films, in addition to affecting the apparent color. The modified WPC/WPI films also exhibited high antiox

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