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Journal articles on the topic 'Film forming formulation'

Author: Grafiati

Published: 4 June 2021

Last updated: 2 February 2022

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1

Pünnel, Larissa Carine, and Dominique Jasmin Lunter. "Film-Forming Systems for Dermal Drug Delivery." Pharmaceutics 13, no. 7 (2021): 932. http://dx.doi.org/10.3390/pharmaceutics13070932.

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Film-forming formulations represent a novel form of sustained release dermatic products. They are applied to the skin as a liquid or semi-solid preparation. By evaporation of the volatile solvent on the skin, the polymer contained in the formulation forms a solid film. Various film-forming formulations were tested for their water and abrasion resistance and compared with conventional semi-solid formulations. Penetration and permeation studies of the formulations indicate a potential utility as transdermal therapeutic systems. They can be used as an alternative to patch systems to administer a

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2

Jassim, Zainab E., Mais F. Mohammed, and Zainab Ahmed Sadeq. "FORMULATION AND EVALUATION OF FAST DISSOLVING FILM OF LORNOXICAM." Asian Journal of Pharmaceutical and Clinical Research 11, no. 9 (2018): 217. http://dx.doi.org/10.22159/ajpcr.2018.v11i9.27098.

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Objective: The aim of the present work was to formulate and evaluate fast dissolving film containing lornoxicam.Materials and Methods: To prepare the film, hydroxypropyl methylcellulose E5 and polyvinyl alcohol (PVA) were used as film-forming polymers by solvent casting method. Glycerine was used as plasticizer, aspartame, and mannitol as sweetener. All prepared films were evaluated for its weight variation, disintegration time, thickness, drug content, pH, dissolution study, and folding endurance. The drug-excipients compatibility study was done using differential scanning calorimetry (DSC) a

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3

Wayal, Vipul, K. Nagasree, and B. A. Vishwanath. "Design, Development and Evaluation of Silk Based Film Forming Spray for Wound Healing." Journal of Drug Delivery and Therapeutics 11, no. 3-S (2021): 15–18. http://dx.doi.org/10.22270/jddt.v11i3-s.4812.

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The objective of the present study is to formulate and evaluate Silk based film forming spray for wound healing. On the wound surface the solution solidifies into a film which can deliver the active moiety on site of action. The spray solution was prepared by simple mixing of active extract of Centella Asiatica, Silk Protein and various film forming polymers. Silk protein form scaffold for active fibroblast movement and Asiaticosides from Centella Asiatica extract improve and fasten collagen synthesis. A clear yellowish solution was obtained. The formulations (F1-F8) had a pH range between 5.5

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4

T, Balakrishna, Vidyadhara S, Murthy Tegk, Ramu A, and Sasidhar Rlc. "FORMULATION AND EVALUATION OF ESOMEPRAZOLE FAST DISSOLVING BUCCAL FILMS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 10 (2018): 193. http://dx.doi.org/10.22159/ajpcr.2018.v11i10.27321.

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Objective: The present study deals with the formulation and evaluation of fast dissolving buccal films for effective treatment option in the gastroesophageal reflux disease.Methods: Esomeprazole fast dissolving buccal films are a convenient formulation of which can be taken with or without water. In the present investigation, polyvinyl alcohol and polyvinylpyrrolidone were used as film-forming agents and polyethylene glycol 400 is taken as plasticizer. Solvent evaporation method was used for the preparation of fast dissolving buccal films.Results: The films were prepared and evaluated for film

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5

Kaza, Rajesh, Sujatha Kumari M, Kishore Babu M, Avinash A, and Nagaraju R. "Biopharmaceutical and Pharmacodynamic Characteri-stics of Telmisartan Oral Disintegrating Films." International Journal of Pharmaceutical Sciences and Nanotechnology 12, no. 2 (2019): 4489–96. http://dx.doi.org/10.37285/ijpsn.2019.12.2.6.

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 This research work was aimed to develop the telmisartan fast dissolving films. Fast dissolving films allow rapid drug dissolution in the oral cavity and thereby bypass the first pass metabolism. Solid dispersions of telmisartan using natural polymers such as hupu gum (HG), guar gum (GG) and xanthan gum (XG) were prepared by kneading technique and the optimized solid dispersion was exploited in the development of rapidly dissolving film. Telmisartan films were prepared by solvent casting method using different grades of HPMC (E5, 50 cps and K4M). Six formulations (FT1-FT6) of telmisartan

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Dangre, Pankaj V., Ram D. Phad, Sanjay J. Surana, and Shailesh S. Chalikwar. "Quality by Design (QbD) Assisted Fabrication of Fast Dissolving Buccal Film for Clonidine Hydrochloride: Exploring the Quality Attributes." Advances in Polymer Technology 2019 (May 5, 2019): 1–13. http://dx.doi.org/10.1155/2019/3682402.

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The present work endeavors fabrication of fast dissolving buccal film of clonidine hydrochloride by employing quality by design (QbD) based approach. The total nine formulations were prepared according to formulation by design helped by JMP software 13.2.1. The patient oriented quality target product profiles were earmarked and on that basis critical quality attributes were identified. Preliminary screening studies along with initial risk assessment eased the selection of film-forming polymer (HPMC E 15) and plasticizer (PEG 400) as CMAs for formulation of films. A 32 full factorial plan was u

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Surini, Silvia, Fungi Gotalia, and Kurnia Sari Setio Putri. "FORMULATION OF MUCOADHESIVE BUCCAL FILMS USING PREGELATINIZED CASSAVA STARCH PHTHALATE AS A FILM-FORMING POLYMER." International Journal of Applied Pharmaceutics 10, no. 1 (2018): 225. http://dx.doi.org/10.22159/ijap.2018.v10s1.50.

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Objective: This study aimed to compare the characteristics of four buccal films formulated with phthalylated cassava starch and their drug deliverypotentials.Methods: An alternative to conventional (oral) drug administration is to administer drugs in a buccal film; however, the required dosage mustbe dissolved in a film-forming polymer with suitable mechanical and mucoadhesive characteristics. Previous studies have produced excipientsby physically and chemically modifying starch, such as by completely pregelatinization and phthalylation it in an aqueous medium under alkalineconditions (pH 8–10

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8

Jamal Mohamed A, Perinbam K, Vahitha V, Devanesan S, and Janakiraman K K. "Povidone iodine loaded film-forming topical gel and evaluation of its chemical stability." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (2020): 148–53. http://dx.doi.org/10.26452/ijrps.v11i1.1799.

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The main aim of this study was to develop Povidone Iodine loaded film-forming gel for excellent wound healing property with various formulations, and corresponding application stratification was prepared with Povidone Iodine, polyethylene glycol-400, polyethylene glycol-4000, aloe vera, and honey. Povidone Iodine is a broad spectrum antiseptic for topical application in the treatment and prevention of infection in wounds. Among the antiseptic and antimicrobial substances, Povidone-Iodine still occupies its position of lasting importance in everyday human and veterinary medicine. Povidone-iodin

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9

Kumar, Y. Shravan, R. Gowthami, Sujitha H, et al. "Formulation and Evaluation of Sumatriptan Succinate Fast Disintegrating Films and Tablets." International Journal of Pharmaceutical Sciences and Nanotechnology 6, no. 2 (2013): 2087–96. http://dx.doi.org/10.37285/ijpsn.2013.6.2.11.

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Sumatriptan succinate is a 5-HT1B/1D receptor agonist which has well established efficacy in treating migraine. The main objective of the study was to formulate Oral Fast Disintegrating Films (ODF) and Oral Fast Disintegrating Tablets (ODT) to achieve a better dissolution rate and further improving the bioavailability of the drug. ODFs were prepared by solvent casting method using film forming polymers like HPMC – E15,5cps,50cps in different ratios & prepared batches of films were evaluated for the drug content, film thickness, disintegration time and in vitro dissolution studies. Among th

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Kumar, Y. Shravan, Deepthi B, and Mounika M. "Formulation and Evaluation of Salbutamol Sulphate Sublingual Films." International Journal of Pharmaceutical Sciences and Nanotechnology 10, no. 5 (2017): 3836–43. http://dx.doi.org/10.37285/ijpsn.2017.10.5.4.

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Salbutamol is a short-acting, selective beta-2-adrenergic receptor agonist used in treatment of asthma and COPD. In the present work, sublingual films of Salbutamol sulphate were developed with a view to enhance the patient compliance and provide quick onset of action. Salbutamol has a bioavailability of 53 - 60%. The goal of the study was to formulate sublingual films of Salbutamol sulphate to achieve a better dissolution rate and further improving the bioavailability of the drug. Sublingual films prepared by solvent casting method using film forming polymers HPMC-E5, HPMC-E15 and Maltodextri

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Gupta, Ashutosh, Jatin Kumar, Surajpal Verma, and Harmanpreet Singh. "APPLICATION OF QUALITY BY DESIGN APPROACH FOR THE OPTIMIZATION OF ORODISPERSIBLE FILM FORMULATION." Asian Journal of Pharmaceutical and Clinical Research 11, no. 14 (2018): 8. http://dx.doi.org/10.22159/ajpcr.2018.v11s2.28508.

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Objective: The present study was done to understand the effect of formulation variables on the quality of orodispersible films using quality by design (QbD) approach as mentioned in ICH Q8 (R2) guideline.Methods: A definitive screening design of experiments (DoE) was used to identify and classify the critical formulation variables affecting critical quality attributes (CQA) using 2×2 factorial design. Based on prescreening study, the critical formulation variables, i.e. concentration of film-forming polymer and plasticizers (propylene glycol and polyethylene glycol 400 [PEG 400]) were kept in

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12

Kale, Rupali, Dattatray Doifode, and Pratiksha Shete. "Film Forming, Antimicrobial and Growth Promoting Wound Healing Spray Formulation." International Journal of Pharmaceutical Investigation 10, no. 3 (2020): 320–25. http://dx.doi.org/10.5530/ijpi.2020.3.57.

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Nagpal, Meenu, Geeta Aggarwal, Upendra Kumar Jain, and Jitender Madan. "OKRA FRUIT GUM-CHITOSAN IMPREGNATED POLYMER NETWORK FILMS: FORMULATION AND SUBSTANTIAL DEPICTION." Asian Journal of Pharmaceutical and Clinical Research 10, no. 10 (2017): 219. http://dx.doi.org/10.22159/ajpcr.2017.v10i10.20362.

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Objective: The present research is aimed at formulation and evaluation of okra fruit gum (OFG)-chitosan (CH) impregnated polymer network films.Methods: The film forming property of the gum attained from fruits of Abelmoschus esculentus was enhanced by co-processing it with CH. Estimation of properties including swelling index (SI), film volume, volume index, film surface contact angle with buffer solutions (pH 1.2, 7.4 or 6.8), work of adhesion (Wa), and spreading coefficient was done.Results: The contact angle and SI of OFG-CH film in both acidic and alkaline buffers were witnessed to be lowe

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14

Socaciu, Maria-Ioana, Melinda Fogarasi, Cristina Anamaria Semeniuc, et al. "Formulation and Characterization of Antimicrobial Edible Films Based on Whey Protein Isolate and Tarragon Essential Oil." Polymers 12, no. 8 (2020): 1748. http://dx.doi.org/10.3390/polym12081748.

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The effects of heat treatment and the addition of tarragon essential oil on physical and mechanical properties of films prepared with 5% whey protein isolate (WPI) and 5% glycerol were investigated in this study. Heat treatment of the film-forming solution caused increases in thickness, moisture content, swelling degree, water vapor permeability (WVP), b*-value, ΔE*-value, transmittance values in the 200–300-nm region, transparency, and puncture resistance of the film, but decreases in water solubility, L*-value, a*-value, transmittance values in the 350–800-nm region, and puncture deformation

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Pawar, Rajat, Ravi Sharma, and Gajanan Darwhekar. "Formulation and Evaluation of Mouth Dissolving Film of Prochlorperazine Maleate." Journal of Drug Delivery and Therapeutics 9, no. 6 (2019): 110–15. http://dx.doi.org/10.22270/jddt.v9i6.3679.

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This research work was aimed to enhance the oral bioavailability and provide faster onset of action of Prochlorperazine maleate (used for the treatment nausea and vomiting) by formulating its mouth dissolving film (MDF). Prochlorperazine belongs to BCS II and oral bioavailability of it’s about 11-15%. The MDF of Prochlorperazine maleate was prepared by solvent casting method using HPMC (film forming agent),Glycerol (plasticizer), Betacyclodextrin (solubilizing agent), Citric acid (saliva stimulating agent), Mannitol (sweetening agent). The formulation was optimized by two factors, three levels

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16

P, Sanjay, Vishal Gupta N, Gowda Dv, and Praveen Sivadasu. "FORMULATION AND EVALUATION OF ORAL DISINTEGRATING FILM OF ATENOLOL." Asian Journal of Pharmaceutical and Clinical Research 11, no. 8 (2018): 312. http://dx.doi.org/10.22159/ajpcr.2018.v11i8.26464.

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Objective: The main objective of the study was to formulate the oral disintegrating films loaded with atenolol by solvent-casting method and to carry out its evaluation studies.Methods: The films were prepared using the film-forming hydrophilic polymer like hydroxypropyl methylcellulose (E-5) and super disintegrant like pectin in various proportions.The formulated oral films were characterized for Fourier transform infrared (FTIR) and morphological evaluations. Various physicochemical parameters such as weight variation, folding endurance, surface pH, in vitro disintegration, and in vitro diss

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Bajaj, Himani, Vinod Singh, Ranjit Singh, and Tirath Kumar. "FABRICATION AND EVALUATION OF CHITOSAN-BASED FILM FORMING GEL OF ACECLOFENAC FOR TRANSDERMAL DRUG DELIVERY." INDIAN DRUGS 58, no. 06 (2021): 68–70. http://dx.doi.org/10.53879/id.58.06.12758.

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The objective of the present study was to prepare a topical film-forming gel of aceclofenac for the treatment of rheumatic diseases, using a safe and effective drug delivery approach. Aceclofenac film-forming gels were prepared using hydroxypropyl methyl cellulose and chitosan polymeric blend in varying concentrations, polyethylene glycol 400 (PEG 400) as a plasticizer, Tween 80 as a permeation enhancer and ethanol as solvent. The prepared film-forming gels were evaluated and the influence of the concentration and ratio of polymeric blends, plasticizer, and ethanol used were investigated. All

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Ahmed, Jwan, Dina Boya, and Hunar Kamal. "Formulation of a fast-dissolving oral film using gelatin and sodium carboxymethyl cellulose." Zanco Journal of Medical Sciences 24, no. 3 (2020): 338–46. http://dx.doi.org/10.15218/zjms.2020.040.

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Background and objective: Orally disintegrating film is a solid dosage form made as an alternative for tablets for pediatric and geriatric patients who have difficulty in swallowing. These formulations are designed to dissolve in the mouth rapidly upon contact with saliva. This study aimed to prepare a thin oro-dispersible film base that can withstand handling in which a drug can be incorporated to provide a new dosage form. Methods: The solvent casting method was used to prepare the films, in which the ingredients were mixed, dissolved, and cast in a Petri dish. Then, they were left to dry in

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Yang, Qingliang, Feng Yuan, Lei Xu, et al. "An Update of Moisture Barrier Coating for Drug Delivery." Pharmaceutics 11, no. 9 (2019): 436. http://dx.doi.org/10.3390/pharmaceutics11090436.

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Drug hydrolytic degradation, caused by atmospheric and inherent humidity, significantly reduces the therapeutic effect of pharmaceutical solid dosages. Moisture barrier film coating is one of the most appropriate and effective approaches to protect the active pharmaceutical ingredients (API) from hydrolytic degradation during the manufacturing process and storage. Coating formulation design and process control are the two most commonly used strategies to reduce water vapor permeability to achieve the moisture barrier function. The principles of formulation development include designing a coati

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Saudagar, R. B., and S. Samuel. "Formulation Development and Evaluation of Topical Film-Forming Lotion Containing Butenafine Hydrochloride." Asian Journal of Pharmacy and Technology 6, no. 4 (2016): 238. http://dx.doi.org/10.5958/2231-5713.2016.00035.0.

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McDonough, Carrie A., Chastity Ward, Qing Hu, Samuel Vance, Christopher P. Higgins, and Jamie C. DeWitt. "Immunotoxicity of an Electrochemically Fluorinated Aqueous Film-Forming Foam." Toxicological Sciences 178, no. 1 (2020): 104–14. http://dx.doi.org/10.1093/toxsci/kfaa138.

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Abstract Aqueous film-forming foams (AFFFs) are complex per- and polyfluoroalkyl substance (PFAS)-containing mixtures used extensively as fire suppressants. AFFF-impacted groundwater and surface water have contaminated drinking water with PFASs in many communities, raising concerns about health effects from drinking water exposures. As individual PFASs have been identified as immune hazards, the immunotoxicity of complex PFAS mixtures is also a concern. Adult female and male C57BL/6 mice were given a commercial AFFF formulation for 10 days via gavage; administered dose was based on combined co

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Cirule, Dace, Errj Sansonetti, Ingeborga Andersone, Edgars Kuka, and Bruno Andersons. "Enhancing Thermally Modified Wood Stability against Discoloration." Coatings 11, no. 1 (2021): 81. http://dx.doi.org/10.3390/coatings11010081.

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Thermal modification of wood has gained its niche in the production of materials that are mainly used for outdoor applications, where the stability of aesthetic appearances is very important. In the present research, spectral sensitivity to discoloration of thermally modified (TM) aspen wood was assessed and, based on these results, the possibility to delay discoloration due to weathering by non-film forming coating containing transparent iron oxides in the formulation was studied. The effect of including organic light stabilizers (UVA and HALS) in coatings as well as pretreatment with lignin

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Kim, Yujin, Moritz Beck-Broichsitter, and Ajay Banga. "Design and Evaluation of a Poly(Lactide-co-Glycolide)-Based In Situ Film-Forming System for Topical Delivery of Trolamine Salicylate." Pharmaceutics 11, no. 8 (2019): 409. http://dx.doi.org/10.3390/pharmaceutics11080409.

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Trolamine salicylate (TS) is a topical anti-inflammatory analgesic used to treat small joint pain. The topical route is preferred over the oral one owing to gastrointestinal side effects. In this study, a poly(lactide-co-glycolide) (PLGA)-based in situ bio-adhesive film-forming system for the transdermal delivery of TS was designed and evaluated. Therefore, varying amounts (0%, 5%, 10%, 20%, and 25% (w/w)) of PLGA (EXPANSORB® DLG 50-2A, 50-5A, 50-8A, and 75-5A), ethyl 2-cyanoacrylate, poly (ethylene glycol) 400, and 1% of TS were dissolved together in acetone to form the bio-adhesive polymeric

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Sadeq, Zainab Ahmed, and Nawal Ayash Rajab. "STUDYING THE EFFECT OF DIFFERENT VARIABLES ON THE FORMULATION OF MUCOADHESIVE BUCCAL PATCHES OF CAPTOPRIL." International Journal of Applied Pharmaceutics 9, no. 2 (2017): 16. http://dx.doi.org/10.22159/ijap.2017v9i2.16345.

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Objective: The objective of this research was to formulate the captopril as mucoadhesive buccal films for hypertension treatment and studying the effect of different variables on the physical and mechanical behavior of the prepared films.Methods: The bucco-adhesive patches were prepared using hydroxyl propyl methyl cellulose K4 (HPMC) as film forming a polymer with secondary polymer included carbopol 934 and eudragit RL100. The patches were prepared by a solvent casting method and evaluated for the weight variation, surface pH, mechanical properties, content, uniformity, ex-vivo mucoadhesive s

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Yadav, Chandrajeet Kumar, Manish Karn, Pinki Yadav, and Roshan Mehta. "Formulation, Optimization and In-vitro Evaluation of Fast Dissolving Oral films of Metoclopramide Hydrochloride by Solvent Casting method." International Journal of PharmTech Research 13, no. 3 (2020): 229–41. http://dx.doi.org/10.20902/ijptr.2019.130314.

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The Present study aimed to prepare fast dissolving oral films (FDFs) of metoclopramide hydrochloride, because of its application in emesis condition where fast onset of action and avoidance of water is highly desirable. Moreover, this dosage form is highly useful in pediatrics, geriatrics and unconscious patients. FDFs were prepared by solvent casting technique with film forming polymers HPMC, PVA & Sodium alginate in varying concentrations with excipients like SLS as surfactant, Glycerol as plasticizer, citric acid as saliva stimulating agent, Sodium Saccharin as sweetening agent. The fil

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Bala, Rajni, Sushil Khanna, and Pravin Pawar. "Design Optimization and In Vitro-In Vivo Evaluation of Orally Dissolving Strips of Clobazam." Journal of Drug Delivery 2014 (September 28, 2014): 1–15. http://dx.doi.org/10.1155/2014/392783.

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Clobazam orally dissolving strips were prepared by solvent casting method. A full 32 factorial design was applied for optimization using different concentration of film forming polymer and disintegrating agent as independent variable and disintegration time, % cumulative drug release, and tensile strength as dependent variable. In addition the prepared films were also evaluated for surface pH, folding endurance, and content uniformity. The optimized film formulation showing the maximum in vitro drug release, satisfactory in vitro disintegration time, and tensile strength was selected for bioav

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Carpenter, Garima, and R. K. Maheshwari. "Formulation and development of fast dissolving oral film of a poorly soluble drug, frusemide with improved drug loading using mixed solvency concept and its evaluation." Journal of Drug Delivery and Therapeutics 8, no. 6 (2018): 132–41. http://dx.doi.org/10.22270/jddt.v8i6.2034.

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The aim of the present research work is to explore the application of mixed solvency concept to formulate and develop a fast dissolving oral film of furosemide with improved drug loading. In the present study, poorly soluble drug, furosemide was tried to be solubilized by employing the combination of physiologically compatible water-soluble additives (solubilizers) to formulate its fast dissolving formulations. For the development of fast dissolving oral film, firstly, different film forming polymers were tested for their film properties. The second fast dissolving layer was also formed and op

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Tamer, Manar Adnan, Shaimaa Nazar Abd-al Hammid, and Balqis Ahmed. "FORMULATION AND IN VITRO EVALUATION OF BROMOCRIPTINE MESYLATE AS FAST DISSOLVING ORAL FILM." International Journal of Applied Pharmaceutics 10, no. 1 (2018): 7. http://dx.doi.org/10.22159/ijap.2018v10i1.22615.

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Objective: The aim of this study was to formulate and in vitro evaluate fast dissolving oral film of practically insoluble bromocriptine mesylate to enhance its solubility and to improve its oral bioavailability by avoiding first pass effect as well as to produce an immediate release action of the drug from the film for an efficient management of diabetes mellitus type II in addition to an improvement of the patient compliance to this patient-friendly dosage form.Methods: The films were prepared by the solvent casting method using hydroxypropyl methylcellulose of grades (E3, E5, E15), polyviny

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Mohd Azharuddin, Theivendren Panner Selvam, Maya Sharma, and Jayesh Dwivedi. "Design development and evaluation of novel ophthalmic nano lipid in situ gel-forming solution using timolol hydrochloride." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 6837–44. http://dx.doi.org/10.26452/ijrps.v11i4.3654.

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The present research work was aimed to design, develop and evaluate the nano lipid-based drug delivery system by incorporating timolol hydrochloride drug for ocular therapy and improve the release of the drug through the ocular route. Nanolipids in situ gels were prepared by film hydration method involving two steps. First nano lipids were formulated with the help of organic solvents, and then they were incorporated into a gel by using gelling agents. FTIR spectrum studies were carried out for drug and the formulations which reveal that there was no interaction between the drug and excipients

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Senthilkumar, K., and C. Vijaya. "Formulation Development of Mouth Dissolving Film of Etoricoxib for Pain Management." Advances in Pharmaceutics 2015 (January 26, 2015): 1–11. http://dx.doi.org/10.1155/2015/702963.

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Etoricoxib is a potent, orally active, and highly selective COX-2 inhibitor that exhibits anti-inflammatory, analgesic, and antipyretic activities. The present research was undertaken to develop mouth dissolving films of etoricoxib to have rapid onset of action. Mouth dissolving film (MDF) is a better alternate to oral disintegrating tablets due to its novelty, ease of use, and the consequent patient compliance. Solubility enhancement and taste masking of etoricoxib were the two challenges solved by formulating drug-inclusion complex with beta-cyclodextrin (BCD). MDF prepared by solvent castin

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Pecora, Tiziana Maria Grazia, Barbara Ragazzo, Walter Bertin, et al. "Rheological Behavior of a New Mucoadhesive Oral Formulation Based on Sodium Chondroitin Sulfate, Xyloglucan and Glycerol." Journal of Functional Biomaterials 12, no. 2 (2021): 28. http://dx.doi.org/10.3390/jfb12020028.

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Background: The study aimed at assessing the mucoadhesive properties and the barrier effect of a formulation, labelled as AL2106, containing sodium chondroitin sulfate (ChS), xyloglucan from tamarind seed extract, and glycerol, by evaluating the capacity to adhere to a layer of mucin, the rheological synergism and the barrier effect in comparison to the marketed Esoxx One medical device. AL2106 is a medical device distributed by Alfasigma SpA, Italy with REF FTP57 (Manufacturer: Labomar SpA); it is analogous to Esoxx One medical device: the two products are drinkable solutions that, after swal

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Zarandona, Iratxe, Mónica Estupiñán, Carla Pérez, Laura Alonso-Sáez, Pedro Guerrero, and Koro de la Caba. "Chitosan Films Incorporated with Exopolysaccharides from Deep Seawater Alteromonas sp." Marine Drugs 18, no. 9 (2020): 447. http://dx.doi.org/10.3390/md18090447.

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Two Alteromonas sp. strains isolated from deep seawater were grown to promote the production of exopolysaccharides (EPS, E611 and E805), which were incorporated into chitosan solutions to develop films. The combination of the major marine polysaccharides (chitosan and the isolated bacterial EPS) resulted in the formation of homogenous, transparent, colorless films, suggesting good compatibility between the two components of the film-forming formulation. With regards to optical properties, the films showed low values of gloss, in the range of 5–10 GU, indicating the formation of non-glossy and

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Meteleva, Olga V., and Ludmila I. Bondarenko. "Optimization of Film Composite Functional Properties for Sewing Products." Key Engineering Materials 869 (October 2020): 382–87. http://dx.doi.org/10.4028/www.scientific.net/kem.869.382.

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The process technological parameters of forming a film composite for making heat-protective clothing have been developed. The peculiarities of its application in sewing production are taken into account. The effect of the initial polymer compositions formulation on the formed composites physical-mechanical and technological properties was studied. It has been found that the use of the composite film material developed reduces the compounds permeability of protective clothing.

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Qin, Jing, and Ni Yin. "Tobramycin Collagen Fast Dissolving Ocular Films for Corneal Tissue Engineering of Keratoconus." Journal of Biomaterials and Tissue Engineering 9, no. 6 (2019): 804–9. http://dx.doi.org/10.1166/jbt.2019.2051.

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Fast dissolving films are a one of novel dosage form in pharmaceutical research. They have convenience and ease of use over other dosage forms such as orally disintegrating tablets and immediate release tablets. In the present research, rapidly dissolving films of Tobramycin were developed using Polyvinyl acetate (PVA) and polyvinyl pyrollidone (PVP) as film forming polymers by solvent casting method. The prepared films were evaluated for drug content, weight variation, thickness and in vitro in vivo disintegration time. The in vitroand in vivodissolving time of the optimized formulation was f

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Yi Sul, Chin, Ana Lucia Morocho-Jacomel, Fabiana Vieira Lima, et al. "In vitro water resistance evaluation of a bioactive sunscreen containing distinct film/ barrier-forming agents." Biomedical and Biopharmaceutical Research Journal 17, no. 2 (2020): 1–14. http://dx.doi.org/10.19277/bbr.17.2.241.

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The use of functional bioactive ingredients and the property of water resistance are differentials in the choice of more effective and safer sunscreens. Water-resistance tests are expensive, time-consuming, and usually performed on subjects that expose them to irradiation and long immersion times. Thus, the study of in vitro water resistance using different film/ barrier-forming agents is relevant for obtaining sunscreen resistant to rinsing. We aimed to evaluate the water resistance of a rutin-based bioactive sunscreen containing distinct film/barrier-forming agents by an in vitro method. The

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Nabil Abdullah та Amit B Patil. "Application of DoE in polymers screening and optimization of in situ topical ϑilm-forming solution for spray formulation". International Journal of Research in Pharmaceutical Sciences 11, SPL4 (2020): 2499–515. http://dx.doi.org/10.26452/ijrps.v11ispl4.4505.

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DoE is a structured and organised method to determine the relationship between the effect of change in the concentration of the independent variables and its impact on the formulation, through establishing a mathematical model. Since the acceptance of the QbD approach by the regulatory authorities across the world, DoE has been widely implemented in the areas of screening and optimisation of the formulations by the pharmaceutical industries. The topical delivery of API still posses' limitations such as insufficient contact time, odd hours of application time, sticking to fabrics, formulation w

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Vangara, Kiran Kumar, Kishore K. Konda, Shiva K. Ravula, Pradeep K. Vuppala, Vijay K. Sripuram, and Sushma Samala. "Formulation Development of Metoprolol Succinate Controlled Release Tablets using Ethyl-cellulose-polyvinyl-pyrrolidone Coating." International Journal of Pharmaceutical Sciences and Nanotechnology 8, no. 2 (2015): 2851–57. http://dx.doi.org/10.37285/ijpsn.2015.8.2.8.

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It is challenging to develop a controlled release (CR) formulation for a freely water soluble drug molecule without using rate controlling polymers in the core matrix. This study is aimed to develop and evaluate cost-effective ethyl cellulose (EC)-polyvinyl pyrrolidone (PVP) film coating that can effectively control the release of freely water soluble drug, metoprolol succinate (MS) and to match that of release profile with its marketed tablet. Simple core tables of MS were compressed and coated with a solution composed of hydrophobic rate controlling polymer, EC and water soluble pore forming

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Jabir, Saba Abdulhadee, and Halah Talal Sulaiman. "PREPARATION AND CHARACTERIZATION OF LAFUTIDINE AS IMMEDIATE RELEASE ORAL STRIP USING DIFFERENT TYPE OF WATER-SOLUBLE POLYMER." International Journal of Applied Pharmaceutics 10, no. 5 (2018): 249. http://dx.doi.org/10.22159/ijap.2018v10i5.28292.

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Objective: The objective of the present study was to design and optimize oral fast dissolving film (OFDF) of practically insoluble drug lafutidine in order to enhance bioavailability and patient compliance especially for a geriatric and unconscious patient who are suffering from difficulty in swallowing.Methods: The films were prepared by a solvent casting method using low-grade hydroxyl propyl methyl cellulose (HPMC E5), polyvinyl alcohol (PVA), and sodium carboxymethyl cellulose (SCMC) as film forming polymers. Polyethylene glycol 400 (PEG400), propylene glycol (PG) and glycerin were used as

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Phaechamud, T., and Juree Charoenteeraboon. "Rapidly Dried Antimicrobial Spray for Foot Deodorant." Advanced Materials Research 506 (April 2012): 473–76. http://dx.doi.org/10.4028/www.scientific.net/amr.506.473.

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This paper aimed to develop a physiologically activated dried antimicrobial spray for foot deodorant and select the suitable components such as film forming agent, solvent, antimicrobial agent and flavoring agents. The evaporation rates, antimicrobial activity, spray pattern, viscosity and cooling effect were evaluated. The developed formulation exhibited the high evaporating rate, high antimicrobial activity, appropriate spray pattern, slightly viscous solution with cooling effect after spraying onto skin. The developed formulation exhibited the potential application as the rapidly dried anti

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Abbas, Ishraq K., Nawal A. Rajab, and Ahmed A. Hussein. "Formulation and In-Vitro Evaluation of Darifenacin Hydrobromide as Buccal Films." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 28, no. 2 (2019): 83–94. http://dx.doi.org/10.31351/vol28iss2pp83-94.

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Darifenacin hydrobromide (DH) is the more recent uroselective M3 receptor antagonist for treating uncomplicated overactive bladder (OAB). This study was aimed to formulate DH as fast dissolving buccal films (FDBFs) using a solvent casting method to enhance patient’s compliance. Films were prepared by using polyvinyl alcohol (PVA) as a film forming polymer. Different types and concentrations of superdisintegrants (croscarmellose sodium, sodium starch glycolate, indion 414) were used to select the best formula by studying the physicochemical properties of the films, disintegration time (DT

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Weng, Verónica, Carla Brazinha, Isabel M. Coelhoso, and Vitor D. Alves. "Decolorization of a Corn Fiber Arabinoxylan Extract and Formulation of Biodegradable Films for Food Packaging." Membranes 11, no. 5 (2021): 321. http://dx.doi.org/10.3390/membranes11050321.

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Corn fiber from the corn starch industry is a by-product produced in large quantity that is mainly used in animal feed formulations, though it is still rich in valuable components, such as arabinoxylans, with proven film-forming ability. During arabinoxylans’ recovery under alkaline extraction, a dark-colored biopolymer fraction is obtained. In this work, a purified arabinoxylan extract from corn fiber with an intense brownish color was decolorized using hydrogen peroxide as the decolorizing agent. Biodegradable films prepared by casting the decolorized extract exhibited a light-yellow color,

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Saudagar, R. B., and P. A. Gangurde. "Formulation, development and evaluation of film-forming gel for prolonged dermal delivery of miconaole nitrate." Research Journal of Topical and Cosmetic Sciences 8, no. 1 (2017): 19. http://dx.doi.org/10.5958/2321-5844.2017.00003.6.

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Oh, Dong-Won, Ji-Hyun Kang, Hyo-Jung Lee, et al. "Formulation and in vitro/in vivo evaluation of chitosan-based film forming gel containing ketoprofen." Drug Delivery 24, no. 1 (2017): 1056–66. http://dx.doi.org/10.1080/10717544.2017.1346001.

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Ногина, Анна, Anna Nogina, Сергей Тихонов, Sergey Tikhonov, Наталья Тихонова, and Nataliya Tikhonova. "The Influence of Biodegradable Food Films on Freshness Indices of Semi-Finished Meat Products." Food Processing: Techniques and Technology 48, no. 4 (2019): 73–78. http://dx.doi.org/10.21603/2074-9414-2018-4-73-78.

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Barrier storage technologies are a promising means of increasing the shelf life of meat products, in particular, food wrap. The authors developed an edible food film with antioxidant and antibacterial properties and tested its efficiency in storage of semi-finished meat products. The formula includes nutrients available for industrial production: structure-forming polysaccharide nature-agar-agar, thickener, stabilizer, antioxidant-arabinogalactan, plasticizer-food glycerin, and universal solvent-distilled water. The food film was produced by extrusion dosing of bulk components and distilled wa

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Pamlényi, Krisztián, Katalin Kristó, Orsolya Jójárt-Laczkovich, and Géza Regdon. "Formulation and Optimization of Sodium Alginate Polymer Film as a Buccal Mucoadhesive Drug Delivery System Containing Cetirizine Dihydrochloride." Pharmaceutics 13, no. 5 (2021): 619. http://dx.doi.org/10.3390/pharmaceutics13050619.

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Currently, pharmaceutical companies are working on innovative methods, processes and products. Oral mucoadhesive systems, such as tablets, gels, and polymer films, are among these possible products. Oral mucoadhesive systems possess many advantages, including the possibility to be applied in swallowing problems. The present study focused on formulating buccal mucoadhesive polymer films and investigating the physical and physical–chemical properties of films. Sodium alginate (SA) and hydroxypropyl methylcellulose (HPMC) were used as film-forming agents, glycerol (GLY) was added as a plasticizer

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Biswas, EH, MA Islam, R. Ferdowsi, YA Yusof, and MG Aziz. "Effect of sugar and starch on chemical and organoleptic parameters of pineapple bar during storage." Progressive Agriculture 30, no. 2 (2019): 227–37. http://dx.doi.org/10.3329/pa.v30i2.42519.

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The aim of this study was to assess the effect of major ingredients on the changes of fundamental quality parameters of pineapple fruit bar during preparation and storage. Four samples were prepared by using Extreme Vertex mixture taking three major ingredients namely fruit pulp, sugar and starch content as factors and non-enzymatic browning data and overall acceptability as responses. The result revealed that compositional differences of different ingredients in formulation fitted to the quadratic linear model at p<0.05. Among the four formulations the liking intensity of formulation F4 co

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Wang, Shiying, Yi Zhang, Liupeng Yang, et al. "Indoxacarb-Loaded Anionic Polyurethane Blend with Sodium Alginate Improves pH Sensitivity and Ecological Security for Potential Application in Agriculture." Polymers 12, no. 5 (2020): 1135. http://dx.doi.org/10.3390/polym12051135.

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Traditional pesticide formulations show poor utilization and environmental safety due to their low foliage adhesion and large auxiliaries. In this study, a novel and environment-friendly indoxacarb formulation was prepared to improve the pesticide’s utilization rate, target control characteristics and ecological security. Indoxacarb-loaded waterborne polyurethane–sodium alginate (PU/SA) nanoemulsions with film forming properties, alkaline responsive release, high effectiveness against Spodoptera litura, and reduced acute contact toxicity for nontarget organisms were successfully prepared. The

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Olechno, Katarzyna, Anna Basa, and Katarzyna Winnicka. "“Success Depends on Your Backbone”—About the Use of Polymers as Essential Materials Forming Orodispersible Films." Materials 14, no. 17 (2021): 4872. http://dx.doi.org/10.3390/ma14174872.

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Polymers constitute a group of materials having a wide-ranging impact on modern pharmaceutical technology. Polymeric components provide the foundation for the advancement of novel drug delivery platforms, inter alia orodispersible films. Orodispersible films are thin, polymeric scraps intended to dissolve quickly when put on the tongue, allowing them to be easily swallowed without the necessity of drinking water, thus eliminating the risk of choking, which is of great importance in the case of pediatric and geriatric patients. Polymers are essential excipients in designing orodispersible films

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Pichayakorn, Wiwat, Prapaporn Boonme, and Wirach Taweepreda. "Cosmetic Pore Packs from Deproteinized Natural Rubber Latex." Advanced Materials Research 844 (November 2013): 466–69. http://dx.doi.org/10.4028/www.scientific.net/amr.844.466.

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Natural rubber latex (NRL) from Hevea brasiliensis consists of cis-1,4-polyisoprene that have many excellent physical properties such as high elasticity, tensile strength, and easily film-forming. However, some proteins in NRL can cause allergy. Hence, this research aimed to prepare cosmetic pore packs from deproteinized NRL (DNRL) that was prepared in-house by enzyme treatment and centrifugation processes. The properties of DNRL were evaluated in terms of amount of remained protein, pH, particle size, polydispersity index, and zeta potential. This DNRL was then formulated the pore pack produc

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Niu, Xiaoqing, Qianyun Ma, Shuiling Li, et al. "Preparation and Characterization of Biodegradable Composited Films Based on Potato Starch/Glycerol/Gelatin." Journal of Food Quality 2021 (January 28, 2021): 1–11. http://dx.doi.org/10.1155/2021/6633711.

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The use of plastics is resisted worldwide. Therefore, finding alternatives to plastic packaging products is an urgent issue. This work was dedicated to the preparation of biodegradable composited films with potato starch, glycerol, and gelatin. The formulation of the biodegradable film was first optimized via response surface methodology combined with the multi-index comprehensive evaluation method that considered physical properties (thickness, water solution (WS), tensile strength (TS) and elongation at break (E%)) and barrier property (light transmittance (T%)). Results indicated that the o

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