Academic literature on the topic 'Filoviridae/physiology'

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Journal articles on the topic "Filoviridae/physiology"

1

Mohan, Gopi S., Ling Ye, Wenfang Li, et al. "Less Is More: Ebola Virus Surface Glycoprotein Expression Levels Regulate Virus Production and Infectivity." Journal of Virology 89, no. 2 (2015): 1205–17. https://doi.org/10.5281/zenodo.14822548.

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(Uploaded by Plazi for the Bat Literature Project) The Ebola virus (EBOV) surface glycoprotein (GP1,2) mediates host cell attachment and fusion and is the primary target for host neutralizing antibodies. Expression of GP1,2 at high levels disrupts normal cell physiology, and EBOV uses an RNA-editing mechanism to regulate expression of the GP gene. In this study, we demonstrate that high levels of GP1,2 expression impair production and release of EBOV virus-like particles (VLPs) as well as infectivity of GP1,2-pseudotyped viruses. We further show that this effect is mediated through two mechani
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2

Schuh, A. J., B. R. Amman, M. E. Jones, et al. "Modelling filovirus maintenance in nature by experimental transmission of Marburg virus between Egyptian rousette bats." Nat Commun 8 (June 12, 2017): 14446. https://doi.org/10.5281/zenodo.13504317.

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(Uploaded by Plazi for the Bat Literature Project) The Egyptian rousette bat (ERB) is a natural reservoir host for Marburg virus (MARV); however, the mechanisms by which MARV is transmitted bat-to-bat and to other animals are unclear. Here we co-house MARV-inoculated donor ERBs with naive contact ERBs. MARV shedding is detected in oral, rectal and urine specimens from inoculated bats from 5-19 days post infection. Simultaneously, MARV is detected in oral specimens from contact bats, indicating oral exposure to the virus. In the late study phase, we provide evidence that MARV can be horizontall
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3

Schuh, A. J., B. R. Amman, M. E. Jones, et al. "Modelling filovirus maintenance in nature by experimental transmission of Marburg virus between Egyptian rousette bats." Nat Commun 8 (June 7, 2017): 14446. https://doi.org/10.5281/zenodo.13504317.

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(Uploaded by Plazi for the Bat Literature Project) The Egyptian rousette bat (ERB) is a natural reservoir host for Marburg virus (MARV); however, the mechanisms by which MARV is transmitted bat-to-bat and to other animals are unclear. Here we co-house MARV-inoculated donor ERBs with naive contact ERBs. MARV shedding is detected in oral, rectal and urine specimens from inoculated bats from 5-19 days post infection. Simultaneously, MARV is detected in oral specimens from contact bats, indicating oral exposure to the virus. In the late study phase, we provide evidence that MARV can be horizontall
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4

Schuh, A. J., B. R. Amman, M. E. Jones, et al. "Modelling filovirus maintenance in nature by experimental transmission of Marburg virus between Egyptian rousette bats." Nat Commun 8 (July 3, 2017): 14446. https://doi.org/10.5281/zenodo.13504317.

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(Uploaded by Plazi for the Bat Literature Project) The Egyptian rousette bat (ERB) is a natural reservoir host for Marburg virus (MARV); however, the mechanisms by which MARV is transmitted bat-to-bat and to other animals are unclear. Here we co-house MARV-inoculated donor ERBs with naive contact ERBs. MARV shedding is detected in oral, rectal and urine specimens from inoculated bats from 5-19 days post infection. Simultaneously, MARV is detected in oral specimens from contact bats, indicating oral exposure to the virus. In the late study phase, we provide evidence that MARV can be horizontall
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5

Schuh, A. J., B. R. Amman, M. E. Jones, et al. "Modelling filovirus maintenance in nature by experimental transmission of Marburg virus between Egyptian rousette bats." Nat Commun 8 (July 10, 2017): 14446. https://doi.org/10.5281/zenodo.13504317.

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Abstract:
(Uploaded by Plazi for the Bat Literature Project) The Egyptian rousette bat (ERB) is a natural reservoir host for Marburg virus (MARV); however, the mechanisms by which MARV is transmitted bat-to-bat and to other animals are unclear. Here we co-house MARV-inoculated donor ERBs with naive contact ERBs. MARV shedding is detected in oral, rectal and urine specimens from inoculated bats from 5-19 days post infection. Simultaneously, MARV is detected in oral specimens from contact bats, indicating oral exposure to the virus. In the late study phase, we provide evidence that MARV can be horizontall
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6

Ferrero, Diego Sebastian, Omar Tomás Gilabert, and Nuria Verdaguer. "Structural insights on the nucleoprotein C-terminal domain of Měnglà virus." Microbiology Spectrum, October 27, 2023. http://dx.doi.org/10.1128/spectrum.02373-23.

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ABSTRACT Filoviruses depend on the nucleoprotein (NP) to accomplish multiple functions during the viral life cycle. NP is the most abundantly expressed viral protein in infected cells and the main component of the viral nucleocapsid. It can be structurally divided into amino- and carboxy- terminal domains (NTD and CTD). The NTD can homo-oligomerize to interact and protect the (−) ssRNA genome, forming long helical structures. The flexible CTD is responsible for the binding of other nucleocapsid proteins and is involved in the formation of inclusion bodies (IBs)—the cytoplasmic sites of nucleoc
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Books on the topic "Filoviridae/physiology"

1

Pattnaik, Asit Kumar, and Michael A. Whitt. Biology and Pathogenesis of Rhabdo- and Filoviruses. World Scientific Publishing Co Pte Ltd, 2015.

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