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Dissertations / Theses on the topic 'FISIC platform'

Author: Grafiati
Published: 23 November 2024

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1

Jolly, Mariette. "Study of many-body dynamics in ion-ion/atom collisions : a joint experimental and theoretical investigation." Electronic Thesis or Diss., Sorbonne université, 2024. http://www.theses.fr/2024SORUS243.

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Étudier les collisions ion-atome et ion-ion permet d'appréhender les probabilités des processus électroniques tels que la capture, l'ionisation et/ou l'excitation en maîtrisant le nombre d'électrons initialement liés à chaque partenaire de la collision. En allant de l'étude d'un système à trois corps (les deux noyaux avec un seul électron) vers des systèmes plus complexes impliquant des électrons supplémentaires permet d'examiner des effets sur la dynamique globale des électrons et par conséquent sur les sections efficaces des processus élémentaires.Dans la section théorique de la thèse, des c
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SUSA, FRANCESCA. "Extracellular vesicles as nanotechnological platform." Doctoral thesis, Politecnico di Torino, 2022. http://hdl.handle.net/11583/2964788.

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FORNASIER, MARCO. "Bio-surfactants-based lipid architectures as nanomedicine platforms." Doctoral thesis, Università degli Studi di Cagliari, 2021. http://hdl.handle.net/11584/306899.

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The use of nanocarriers for drug delivery and imaging purposes have highly increased in the last decades. Both hard and soft matter-based formulations can provide selective and efficient treatment in several administration routes. Indeed, the biocompatibility and the biodegradability of the formulations represent a key requirement in order to translate the in vitro studies into in vivo investigations. Therefore, lipids are a safe choice as building blocks to formulate a large variety of liquid crystalline architectures in water. Vesicles, hexosomes and cubosomes have been adopted as nanomedic
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Boccioletti, Luca. "Programmable electronic platform for the remote control of the cell-migration galvanotaxis." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amslaurea.unibo.it/10289/.

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Il presente lavoro di tesi nasce come collaborazione tra il Laboratorio di Progettazione Elettronica e il Laboratorio di Microscopia a Fluorescenza del Dipartimento di Fisica e Astronomia dell' Università di Bologna. In particolare nasce dalla volontà di dotare il dipartimento di un apparato sperimentale in grado di svolgere studi sulla Galvanotassia, un fenomeno biologico consistente nella migrazione di cellule sottoposte a stimolazione elettrica. La Galvanotassia è nota da fine '800 ma non sono ancora chiari i meccanismi cellulari che la provocano. Una migliore comprensione di tale fenomeno
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ANGELINI, ANGELO. "Photon Management on a Photonic Crystal Platform." Doctoral thesis, Politecnico di Torino, 2015. http://hdl.handle.net/11583/2611159.

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A multilayered dielectric structure, namely a one dimensional photonic crystal (1DPC), is proposed as a suitable platform for photon management, due to the low absorption of the dielectric materials. When properly designed, a 1DPC can sustain surface electromagnetic modes called Bloch Surface Waves (BSWs). In this PhD Thesis it is shown how light coupled to BSW can be focused or guided by means of ultrathin polymeric refractive structures directly patterned on the surface. Moreover, by patterning the surface with surface relief gratings, far-field radiation can be efficiently coupled to the su
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AMBROSETTI, ELENA. "Development of an integrated nanotechnology-based platform for the early diagnosis of cancer: assessment of circulating biomarkers in Her2-positive breast cancer and role of novel binders in biomarkers detection." Doctoral thesis, Università degli Studi di Trieste, 2017. http://hdl.handle.net/11368/2908116.

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Early detection of cancer plays a crucial role in determining disease prognosis. The major challenge consists in the ability of identifying the disease through the quantification of a set of specific biomarkers in tissues and/or, more interestingly, released in the bloodstream. Non-invasiveness, sensitivity, parallelization, low cost, are some of the most relevant keywords in this field. Hence the development of miniaturized devices for the early detection of cancer is at the core of nanodiagnostics, requiring the recognition and quantification of low amounts of specific disease biomarkers, th
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Santini, Giulia. "The ISHTAR website on the MOODLE e-learning platform: a starting point." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amslaurea.unibo.it/18011/.

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In questa tesi magistrale ho studiato e analizzato gli strumenti e le risorse offerte dalla piattaforma di e-learning MOODLE e verificato quali opportunità offre per l'insegnamento e l'apprendimento. Ho effettuato, tenendo conto di queste risorse e di concetti di didattica della fisica, il trasferimento di uno dei corsi presenti sul sito ISHTAR dell'Università di Bologna, facendone la traduzione in inglese e integrandolo con elementi multimediali e forme di interfaccia, verifica e comunicazione proprie della piattaforma. Per un secondo corso, ho studiato e confrontato diverse metodologie di im
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Corvaglia, Stefania. "Nanoscale platform to study unstructured proteins interactions." Doctoral thesis, Università degli studi di Trieste, 2014. http://hdl.handle.net/10077/9975.

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2012/2013<br>Le proteine intrinsecamente disordinate (IDP), nello stato nativo non ripiegate, sono inclini all’aggregazione e direttamente correlate con lo sviluppo di malattie amiloidi. Tra queste, ci siamo focalizzati sullo studio dell’alfa-Sinucleina (AS), una proteina coinvolta nella malattia di Parkinson, un disturbo neurodegenerativo caratterizzato dalla degenerazione dei neuroni dopaminergici e l’accumulo di AS in placche amiloidi. Sebbene lo studio delle interazioni AS-dopamina sia di importanza cruciale nella comprensione dei meccanismi responsabili dello sviluppo della malattia, tutt
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Pozza, Gianluca. "Development of an Optofluidic Platform in Lithium Niobate." Doctoral thesis, Università degli studi di Padova, 2015. http://hdl.handle.net/11577/3424115.

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Optofluidics is a promising interdisciplinary research and technological field, thanks to its wide potential of application in sector like medicine, chemistry, biology and environmental science. In this context the study of innovative materials including their properties, their efficiency, their limits and their possibility of leading to miniaturized devices is the key point for the overcoming of currently adopted strategies. A promising material that could satisfy new optofluidic requirements is Lithium Niobate (LiNbO3 - LN) thanks to its excellent optical and nonlinear optical properties. I
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Marcante, Andrea. "PD_manager: an mHealth platform for Parkinson's disease Management." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3421871.

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Parkinson’s disease (PD) current clinical management is mostly based on patient’s subjective report about the effects of treatments and on medical examinations that unfortunately represent only a snapshot of a highly fluctuating clinical condition. This traditional approach requires time, it is biased by patient’s judgment and is often not completely reliable, especially in moderate advanced stages. The main purpose of the EU funded project PD_manager (Horizon 2020, Grant Agreement n° 643706) is to build and evaluate an innovative, mHealth, patient-centric system for PD remote monitoring. Afte
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11

Sogne, E. "NOVEL PLATFORM FOR BIOSENSING APPLICATION BASED ON CLUSTER-ASSEMBLED MATERIALS." Doctoral thesis, Università degli Studi di Milano, 2015. http://hdl.handle.net/2434/265569.

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Rapid methods to identify bacteria in biological samples are important for prompt antimicrobial therapy. The current detection methods are classical biological sample cultures and biochemical tests, which are however, time-consuming and not highly sensitive. A novel and highly performing approach is offered by aptamers acting as recognition elements able to detect epitopes on the surface of a bacterium. Aptamers interacting with specific bacteria are known and then could provide a solid base for developing promising solutions for this issue. With this PhD work I intended to tackle one drawback
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MELLE, GIOVANNI. "Development of a Novel Platform for in vitro Electrophysiological Recording." Doctoral thesis, Università degli studi di Genova, 2020. http://hdl.handle.net/11567/1000590.

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The accurate monitoring of cell electrical activity is of fundamental importance for pharmaceutical research and pre-clinical trials that impose to check the cardiotoxicity of all new drugs. Traditional methods for preclinical evaluation of drug cardiotoxicity exploit animal models, which tend to be expensive, low throughput, and exhibit species-specific differences in cardiac physiology (Mercola, Colas and Willems, 2013). Alternative approaches use heterologous expression of cardiac ion channels in non-cardiac cells transfected with genetic material. However, the use of these constructs an
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13

PEZZUOLI, DENISE. "Nanofluidic platforms for sensing applications in biomedical and environmental fields." Doctoral thesis, Università degli studi di Genova, 2020. http://hdl.handle.net/11567/1001584.

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Nowadays, nanofluidic platforms are powerful tools for carrying out fundamental studies on molecular-scale phenomena. Typically, the use of these systems results in being crucial both in biomedical and environmental fields. In fact, they are widely exploited for many applications such as detection, concentration, sorting, counting and sizing of several nano-objects such as nanoplastics, viruses, antibodies and DNA. This is the context in which my Ph.D. research project is inserted. I have worked on the development of elastomeric nanofluidic platforms, equipped with different nanostructures,
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14

GEBREYES, WONDIMU ALEMU. "AN ELECTROCHEMICAL MICROFLUIDIC BIOSENSOR PLATFORM FABRICATED BY ADDITIVE MANUFACTURING AND SUPERSONIC CLUSTER BEAM DEPOSITION." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/613065.

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Fused Filament Fabrication (FFF) three-dimensional printing have attracted much attention for fabrication of microfluidic platforms used to construct electrochemical microfluidic biosensors because of high process speed, low production costs and the possibility of manufacturing directly from virtual data. Because of poor adhesion between metal electrodes fabricated using conventional techniques and FFF printed thermoplastic substrates, electrodes are usually integrated into the devices either modularly or using adhesive layers placed at the bottom of fluidic channels. These have hindered the e
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15

Zamboni, Riccardo. "Study of light driven phenomena for optofluidic applications in Lab-on-a-chip platforms in lithium niobate." Doctoral thesis, Università degli studi di Padova, 2019. http://hdl.handle.net/11577/3423177.

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Since the growing interest in Lab-On-a-Chip (LOC) applications, the demand for a high multifunctional and portable devices in order to increase the achievement of complex laboratories analysis on a small size chips. This need pushed the research to integrate in the substrates several tools with different tasks, and consequently, the requirements of the material exploited become rapidly more restricted. In particular, the performances of multiple toolkit device are related to its capabilities of combining and matching stages, thus avoiding any detrimental interferences between the material prop
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16

VERNA, ALESSIO. "A transistor based sensing platform and a microfluidic chip for a scaled-up simulation of controlled drug release." Doctoral thesis, Politecnico di Torino, 2015. http://hdl.handle.net/11583/2591165.

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The framework of my thesis are Biomedical (or Biological) Microelectromechanical Systems (BioMEMSs). Two fields in which this discipline is involved are sensors and fluidics. Functionalized organic materials are under investigation to be the means for target biological sensing, and sensors are evolving to be integrated in fluidics platforms in order to produce in the future new small portable diagnostic devices. On the other hand one of the challenges of micro and nanofluidic technology is the fabrication of drug release devices, in order to control the amount of drug present in an organism. I
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17

Salvadori, Andrea. "Design and development of a cross-platform molecular viewer for Immersive Virtual Reality systems." Doctoral thesis, Scuola Normale Superiore, 2017. http://hdl.handle.net/11384/85810.

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18

CAVALLINI, Susanna. "Organic Light Emitting Transistors: A Platform for the Integration of Innovative Nanophotonic Structures." Doctoral thesis, Università degli studi di Ferrara, 2014. http://hdl.handle.net/11392/2389387.

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The focus of this Ph.D. thesis is the investigation of the opto-electronic performances and photonic characteristics of Organic Light Emitting Transistors (OLETs). These promising multifunctional devices unify the switching properties of transistors with the light emission capability of light-emitting diodes. The OLETs that have been studied in this research present a peculiar trilayer configuration, which can allow to obtain high light emission efficiency by reducing the quenching processes inherent to the device structure. For these devices, the exciton formation, the light outcoupli
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19

BASTA, Luca. "Defect-engineered graphene functionalization via cycloaddition reaction – towards a versatile platform for nanoscale devices and 3D heterostructures." Doctoral thesis, Scuola Normale Superiore, 2022. https://hdl.handle.net/11384/126242.

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In recent years it has been shown that the outstanding properties of graphene, a direct consequence of its unique 2D structure, could be further tailored by surface functionalization with suitable materials, towards a fine tuning of the system's physical and chemical properties. In particular, the covalent functionalization of graphene using organic functional groups has been explored as a pivotal step towards the formation of graphene composites at the nanoscale. Alongside the commonly diffused approach with diazonium salts (abundant and quick but hard to control), a more selective and contro
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20

REIS, G. A. LINO DOS. "Microfabrication and characterization of cellon-chip platforms on poly (amidoamine) hydrogels." Doctoral thesis, Università degli Studi di Milano, 2010. http://hdl.handle.net/2434/148436.

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The control of cell growth, proliferation and differentiation on biomaterials surfaces is of fundamental importance for regenerative medicine, prosthetics, or cell-based assays. The microfabrication of cell-on-chip platforms based on a new family of poly (amidoamine) hydrogels, are promising for in vitro and in vivo applications. Hydrogels present characteristics that mimics biological environments, such as the cross-linked nature of the extracellular matrix, the tissue properties (high water content), and the permeability to oxygen and metabolites. Hydrogels based on poly (amidoamine) results
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21

CIONTI, CAROLINA. "PHOTO-RESPONSIVE OXIDES AS PLATFORMS FOR ENVIRONMENTAL REMEDIATION, HYBRID MATERIALS SYNTHESIS AND SMART SYSTEMS." Doctoral thesis, Università degli Studi di Milano, 2022. http://hdl.handle.net/2434/916845.

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Photoactive semiconductors are a hot topic of research due to their applications in environmental remediation, photovoltaics, smart devices, light-activated synthesis and self-cleaning surfaces. Among them, oxide semiconductors play a main role thanks to their wide availability, stability, ease of preparation and tunable surface properties. In this context, my Ph.D. focused on the application of oxide semiconductors for three main purposes: pollutant remediation, photocatalytic synthesis of hybrid materials, and smart systems for the controlled release of active substances. Alongside this main
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22

Porciani, David. "Aptamers against transferrin receptor: rational engineering of nanoscale platforms for targeted delivery of molecular payloads." Doctoral thesis, Scuola Normale Superiore, 2016. http://hdl.handle.net/11384/86212.

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23

Pintossi, C. "CARBON-BASED HYBRID PLATFORMS FOR NOVEL PHOTOVOLTAIC DEVICES: BURIED INTERFACE CHEMISTRY AND CHARGE CARRIERS DYNAMICS." Doctoral thesis, Università degli Studi di Milano, 2016. http://hdl.handle.net/2434/362241.

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Current photovoltaic (PV) market is strongly dominated by an intense use of silicon. Although it is the second most abundant element on the Earth crust, after oxygen, Si is never present in its pure form but always bounded with other elements, and relatively complex and expensive purification procedures are needed in order to have clean, crystalline and optimally doped pure silicon. This issue, joined with the ever-increasing demand of clean Si by almost all the technological modern applications, led scientists all over the world to look for suitable alternatives. One of the most promising
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Sonato, Agnese. "Nanofabrication and development of surface plasmon resonance platforms for sensing applications." Doctoral thesis, Università degli studi di Padova, 2014. http://hdl.handle.net/11577/3423741.

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In recent decades, surface plasmon resonance has known a growing interest in the realization of miniaturized devices for label-free sensing applications due to the need of increasing the sensitivity of the sensor and limiting the consumption of material. This work is aimed to the realization of plasmonic nanostructures that can be applied to different sensoristic fields in order to create a starting point for the realization of miniaturized sensors for a wide range of applications. In this context a careful study of geometry and materials suitable for creating the starting plasmonic platform
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25

BLANCO, SACRISTAN JAVIER. "Investigation of terrain control on dryland functioning and composition using multiple remote sensing sensors and platforms." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2020. http://hdl.handle.net/10281/294894.

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Le zone aride sono tra le aree più sensibili al cambiamento globale e i modelli prevedono un incremento della loro superficie nei prossimi decenni. La morfologia del terreno ha un ruolo chiave nella distribuzione dell'acqua e delle sostanze nutritive nelle zone aride e nella determinazione della loro composizione. Questi ambienti sono composti da vegetazione e suolo nudo, molte volte colonizzato da biocroste, che si prevede subiranno cambiamenti nella composizione. Il telerilevamento è stato evidenziato come uno strumento importante per il monitoraggio delle zone aride. Si tratta di un approcc
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26

Meneghello, Anna. "Surface plasmon resonance based platforms for clinical and environmental biosensing applications." Doctoral thesis, Università degli studi di Padova, 2016. http://hdl.handle.net/11577/3424512.

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My PhD Thesis work, developed in Veneto Nanotech Laboratories (Nanofab in Marghera, LaNN in Padova and ECSIN in Rovigo), was aimed at the exploitation of the Surface Plasmon Resonance (SPR) phenomenon for the set-up of biosensing platforms for clinical and environmental applications. In particular, two types of SPR-based platforms were set-up and optimised: the first one was an oligonucleotide-based platform for the detection of Cystic Fibrosis (CF) causing mutations while the second one was an antibody-based platform for the detection of Legionella pneumophila whole cells. Both sensors are
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27

FALLATI, LUCA. "Remote sensing across multiple platforms and spatial scales: monitoring and assessment of eco-geomorphological changes on climatically sensitive coastal areas." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2020. http://hdl.handle.net/10281/262344.

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Con l’avvento dell’Antropocene, una nuova epoca geologica caratterizzata dall’impatto delle attività umane sul clima e l’ambiente, il sistema Terra si trova a fronteggiare un netto aumento di fattori di stress di diversa origine. Tra tutti gli ecosistemi del pianeta, quelli delle regioni costiere sono sicuramente tra i più dinamici e vulnerabili. Questi sono caratterizzati da marcate dinamiche spazio-temporali e la loro posizione tra l’interfaccia terra acqua li rende soggetti ad impatti sia di origine terrestre che marina. Le minacce derivanti dai cambiamenti climatici e da un diretto impatto
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SCHIERA, DANIELE SALVATORE. "Towards Energy Systems Integration: a holistic methodology, software platform, and toolset for modelling and simulation of Cyber-Physical-Social Energy Systems." Doctoral thesis, Politecnico di Torino, 2022. https://hdl.handle.net/11583/2973800.

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