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1

Burgess, N. A., H. E. Moore, J. O. Williams, and M. H. Lewis. "A Review of Pancreatico-Pleural Fistula in Pancreatitis and Its Management." HPB Surgery 5, no. 2 (1992): 79–86. http://dx.doi.org/10.1155/1992/90415.

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Pancreatico-pleural fistula is a rare condition in which pancreatic enzymes drain directly in to the pleural cavity, most commonly from an enlarging pseudocyst. We review the literature on the causes, investigations and treatment of pancreatico-pleural fistulae and compare this with our own experience of the case of a 41 year old man with a left sided pancreatico-pleural fistula associated with pancreatic duct obstruction. The fistula could not be demonstrated by USS, CT or ERCP, and after these investigations the patient was managed conservatively. However, deterioration in the patients' cond
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2

Abdulkarim, Shafic, Saud Aldeghaither Aldeghaither, and Dan L. Deckelbaum. "Complete major pancreatic duct disruption complicated by pancreatico-atmospheric fistula following blunt upper abdominal trauma." Archive of Clinical Cases 10, no. 4 (2023): 179–82. http://dx.doi.org/10.22551/2023.41.1004.10270.

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Pancreatic injury post blunt abdominal trauma is exceedingly rare. When complete major pancreatic duct (MPD) disruption occurs, a disconnection between the pancreas and the duodenum can take place, ultimately leading to fistula formation. We describe a case of MPD disruption following blunt abdominal trauma, complicated by a fistula between the pancreas and an open abdomen (pancreatico-atmospheric fistula). Although the fistula was managed using standard methods for treating pancreatic fistulas, wound care was a significant challenge in this case where the fistula exteriorized into an open abd
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3

Çetinkaya, Gökay, Ahmet Cihangir Emral, and Mustafa Kerem. "The Role of Inflammatory Indices in Predicting Pancreatic Fistula After Distal Pancreatectomy." Harran Üniversitesi Tıp Fakültesi Dergisi 22, no. 2 (2025): 255–59. https://doi.org/10.35440/hutfd.1635628.

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Background: The significance of inflammatory markers in forecasting pancreatic fistula development has not been thoroughly investigated in patients who have undergone distal pancreatectomy. This study seeks to assess the predictive value of postoperative inflammatory indices, particularly SII (systemic immune inflammation index), NLR (neutrophil-to-lymphocyte ratio) and PLR (platelet-to-lymphocyte ratio), concerning the onset of pancreatic fistula in these patients. Materials and Methods: This retrospective study analyzed patients who underwent distal pancreatec-tomy for pancreatic cancer betw
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4

Grobmyer, Stephen R., Darrell L. Hunt, Christopher E. Forsmark, Peter V. Draganov, Kevin E. Behrns, and Steven N. Hochwald. "Pancreatic Stent Placement is Associated with Resolution of Refractory Grade C Pancreatic Fistula after Left-Sided Pancreatectomy." American Surgeon 75, no. 8 (2009): 654–58. http://dx.doi.org/10.1177/000313480907500804.

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Pancreatic fistula have been a source of significant morbidity and mortality after left-sided pancreatectomy. The majority of fistulas are classified as Grade A and resolve quickly with no intervention. Grade C pancreatic fistulas, which require percutaneous or operative drainage, are less common and may be associated with morbidity and mortality. We used postoperative endoscopic pancreatic stent placement as an adjunctive strategy in the management of refractory Grade C pancreatic fistulas. Patients undergoing endoscopic pancreatic stent placement for persistent, refractory peripancreatic flu
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5

Aziz, Hassan, Shahzaib Ahmad, Faisal S. Jehan, Wasif M. Saif, and Syed Ahmad. "Management of Refractory Pancreatic Fistula: A Review of Literature." Pancreas – Open Journal 5, no. 2 (2022): 23–27. http://dx.doi.org/10.17140/poj-5-117.

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Background Chronic non-healing or refractory pancreatic fistulae are rare complications of pancreatic surgery (pancreaticoduodenectomy, distal pancreatectomy) or pancreatitis. Materials and Methods We conducted a thorough literature search of electronic databases such as PubMed, Google Scholar, BioMed Central, and Cochrane Library using the keywords and medical subject headings (MeSH) terms “chronic pancreatic fistula”, “post-operative fistula”, “fistula management” and “refractory pancreatic fistula”. The purpose of this review is to evaluate the management options for refractory pancreatic f
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6

Barannikov, Anton Yu, Vladimir D. Sakhno, Vladimir M. Durleshter, Laura G. Izmailova, Andrei V. Andreev, and Evgenii V. Tokarenko. "Differentiated approach to pancreatic-enteroanastomosis in pancreaticoduodenal resection: a clinical experimental controlled trial." Kuban Scientific Medical Bulletin 28, no. 5 (2021): 29–46. http://dx.doi.org/10.25207/1608-6228-2021-28-5-29-46.

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Background. Despite decreasing mortality in pancreaticoduodenal resection, the incidence of postoperative complications in such patients remains high. The choice and formation of “reliable” pancreatic-enteroanastomosis remain relevant.Objectives. The improvement of immediate surgery outcomes in pancreaticoduodenal resection via development of a differentiated algorithm for pancreatic-enteroanastomosis formation.Methods. A prospective non-randomised controlled trial enrolled 90 patients with a pancreaticoduodenal resection surgery. The patients were divided in three cohorts, A (n = 30), B (n =
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7

Valikhnovska, K. G. "Retrospective analysis of risk factors for occurrence of pancreatic fistula in patients following pancreaticoduodenectomy." Reports of Vinnytsia National Medical University 22, no. 3 (2018): 436–41. http://dx.doi.org/10.31393/reports-vnmedical-2018-22(3)-07.

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Pancreaticoduodenectomy still is a “gold standard” in treatment of hepatopancreaticobiliary tumors. The causes of pancreatic fistula were analyzed in 414 patients aged from 22 to 81 following pancreaticoduodenectomy due to periampullary tumors. The said patients were operated on during the period from 2008 to 2017. The aim of this study is to improve outcomes of pancreatic resection based on a retrospective analysis of the causes of postoperative pancreatic fistulae and the development of a range of measures to prevent the above complication. Influence of risk factors of pancreatic fistula for
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8

Satchithanandha, Vysheki, Jin-Soo Park, and Charbel Sandroussi. "The detours of pancreatic ducts, internal pancreatic fistulas: a rare complication of chronic pancreatitis." International Surgery Journal 11, no. 5 (2024): 784–86. http://dx.doi.org/10.18203/2349-2902.isj20241141.

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Internal pancreatic fistula occurs due to the disruption of the pancreatic duct, resulting in communication with it and another epithelial surface. A rare variant is the pancreaticopleural and pancreaticogastric fistula, typically associated with chronic necrotising pancreatitis, resulting from posterior disruption of the pancreatic duct. It is a complex disease with different aetiologies, varied clinical presentations and multiple management options. Unlike postoperative pancreatic fistula, internal pancreatic fistula lacks guidelines for classification and management. Once an internal fistul
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9

Aswani, Yashant, Shehbaz MS Ansari, Ulhaas S. Chakraborty, Priya Hira, and Sudeshna Ghosh. "Where there is pancreatic juice, there is a way: Spontaneous fistulization of severe acute pancreatitis-associated collection into urinary bladder." Indian Journal of Radiology and Imaging 30, no. 04 (2020): 529–32. http://dx.doi.org/10.4103/ijri.ijri_349_20.

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AbstractPancreatic fluid collections (PFC) are notorious for their extension beyond the normal confines of the pancreatic bed. This distribution is explained by dissection along the fascial planes in retroperitoneum due to the digestive enzymes within the PFC. In genitourinary track, PFCs have been described to involve the kidneys and the ureters. We report a case of severe acute necrotizing pancreatitis in a 28-year-old male, chronic alcoholic, who on readmission developed features of cystitis. The urine was turbid but did not show significant bacteriuria. Close location of the PFC near the u
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10

Ignjatovic, Dragan, Goran Kronja, Sidor Misovic, and Dragan Mirkovic. "External transluminal drainage of the pancreatic duct due to fistula caused by postbioptic pancreatic necrosis." Vojnosanitetski pregled 62, no. 5 (2005): 413–16. http://dx.doi.org/10.2298/vsp0505413i.

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Background. Pancreatic fistulas are not frequent after the needle biopsy of the pancreatic head. The aim was to present a patient with this type of fistula who was managed using the surgical method never previously applied in our surgical practice. Case report. In our patient, pancreatic fistula appeared at the site of the needle biopsies due to the development of the necrosis. Since the conservative treatment with octreotide and the total parenteral nutrition were without result, we turned to the surgical treatment by placing a silicone prosthesis along the pancreatic duct into the duodenum,
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11

Tudor, A., C. Molnar, C. Nicolescu, et al. "Cephalic Duodeno-Pancreatectomy with Pancreatic-Gastric Anastomosis with Double Purse String, in Patient with Lithiasis and Tumoral Jaundice - Case Report." Acta Medica Marisiensis 60, no. 5 (2014): 227–30. http://dx.doi.org/10.2478/amma-2014-0047.

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Abstract Introduction: One of the most feared complications after cephalic duodeno-pancreatectomy remains pancreatic fistula. In recent years, various methods of pancreatico-digestive reconstruction were performed in order to reduce the rate of pancreatic fistula. One of these methods is pancreatico-gastric reconstruction by using two purse string threads. Case report: We present in this article a patient with jaundice with mixed etiology: tumoral and lithiasic. Subjectively, the patient accused sclerose-skin-jaundice, right upper quadrant and epigastric pain, nausea and vomiting. Computed tom
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12

Mastalier, Bogdan, Victor Cauni, Constantin Tihon, et al. "Pancreaticogastrostomy versus Pancreaticojejunostomy and the Proposal of a New Postoperative Pancreatic Fistula Risk Score." Journal of Clinical Medicine 12, no. 19 (2023): 6193. http://dx.doi.org/10.3390/jcm12196193.

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Despite the substantial decrease in mortality rates following a pancreaticoduodenectomy to less than 5%, morbidity rates remain significant, reaching even 73%. Postoperative pancreatic fistula is one of the most frequent major complications and is significantly associated with other complications, including patient death. Currently, there is no consensus regarding the ideal type of pancreatic anastomosis, as the question of the choice between a pancreaticogastrostomy and pancreaticojejunostomy is still open. Furthermore, worldwide implementation of an ideal pancreatic fistula risk prediction s
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13

Desyateryk, V. I., O. V. Kotov, S. P. Mikhno, Ye O. Okhotnik, and M. P. Krasnov. "Pancreatopleural fistula as a complication of necrotizing pancreatitis (clinical case)." Medicni perspektivi 28, no. 2 (2023): 191–96. http://dx.doi.org/10.26641/2307-0404.2023.2.283421.

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Acute pancreatitis is a disease that is accompanied by systemic inflammatory response syndrome and polysystemic dysfunction. Often acute pancreatitis leads to damage to various organs, including: pleura, mediastinum, cardiovascular structures. These complications cause difficulties in diagnosing and treating patients. In this review, we discuss the complications of acute pancreatitis, focusing on the diagnosis and treatment of pancreatopleural fistulas. Pancreatopleural fistula is a rather rare complication observed in patients with both acute and chronic pancreatitis due to traumatic or iatro
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14

Desyateryk, V.I., O.V. Kotov, S.P. Mikhno, Ye.O. Okhotnik, and M.P. Krasnov. "Pancreatopleural fistula as a complication of necrotizing pancreatitis (clinical case)." Medicni perspektivi 28, no. 2 (2023): 191–96. https://doi.org/10.26641/2307-0404.2023.2.283421.

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Acute pancreatitis is a disease that is accompanied by systemic inflammatory response syndrome and polysystemic dysfunction. Often acute pancreatitis leads to damage to various organs, including: pleura, mediastinum, cardiovascular structures. These complications cause difficulties in diagnosing and treating patients. In this review, we discuss the complications of acute pancreatitis, focusing on the diagnosis and treatment of pancreatopleural fistulas. Pancreatopleural fistula is a rather rare complication observed in patients with both acute and chronic pancreatitis due to traumatic or iatro
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15

Shaeir, Sayed Shaker, Mohamed Atef ElKordy, Mohamed Emam Sobeih, Rasha Mahmoud Allam, and Ayman Hanafy. "Pancreatico-jejunostomy versus pancreatico-gasrostomy after pancreatico-duodenectomy in decreasing postoperative pancreatic fistula." Egyptian Journal of Surgery 42, no. 2 (2023): 473–81. http://dx.doi.org/10.4103/ejs.ejs_91_23.

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Background Pancreatico-duodenectomy is still the cornerstone in curating pancreatic and periampullary cancers. Many techniques for pancreatic anastomosis were described. Pancreatico-gastrostomy (PG) may be a suitable technique, especially in small pancreatic ducts where the stitching of duct to mucosa may be difficult. Still, the results of pancreatico-gastrostomy compared to pancreatico-jejunostomy (PJ) in terms of morbidity are not well studied; hence, this study was designed to investigate. Objective To compare pancreatico-gastrostomy versus pancreatico-jejunostomy post pancreatico-duodenec
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16

Barmina, T. G., L. T. Khamidova, O. A. Zabavskaya, et al. "Diagnosis of gastrointestinal fistulas in pancreatic necrosis by X-ray and computed tomography." Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH) 14, no. 5 (2024): 128–36. https://doi.org/10.20340/vmi-rvz.2024.5.mlm.4.

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The purpose of the study: to clarify the possibilities of using X-ray research methods in the framework of a comprehensive diagnosis of gastrointestinal fistulas in pancreatic necrosis.Materials and methods. The analysis of the results of X-ray examination of 23 patients with pancreatic necrosis complicated by the formation of gastrointestinal tract fistulas (GI tract) is presented. All patients underwent computed tomography (CT) of the abdominal cavity and retroperitoneal space with bolus contrast enhancement and X-ray fistulography. Contrast examination of the upper gastrointestinal tract af
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17

Sguinzi, R., F. Pugin, C. Bader, et al. "Massive Haematochezia due to Splenic Artery Bleeding into the Colon: Unusual Manifestation of Advanced Pancreatic Cancer." Case Reports in Surgery 2023 (January 12, 2023): 1–5. http://dx.doi.org/10.1155/2023/7443508.

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We describe a case of an uncommon early pancreatic cancer presentation in a patient in his 60s who had haemorrhagic shock from extensive haematochezia and required blood transfusions as well as surveillance in an intensive care unit. A splenic artery pseudoaneurysm that had been effectively embolized by angiography was seen to be actively bleeding into the colon lumen on a computerized tomography (CT) scan along with a necrotic mass of the pancreatic tail. A pancreatic mucinous adenocarcinoma was diagnosed by a transgastric biopsy. A pancreatico-colic fistula was discovered by CT scan after a
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18

Tudor, A., C. Molnar, C. Copotoiu, et al. "Pancreatico-Gastric Anastomosis with and without Sutures – Experimental Swine Model." Acta Medica Marisiensis 61, no. 2 (2015): 105–9. http://dx.doi.org/10.1515/amma-2015-0032.

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Abstract Objectives. The aim of our study is to identify a surgical technical that has the lowest rate of pancreatic fistulas in pancreatico-gastric anastomosis following duodenopancreatectomies. We studied pancreatico-gastric anastomosis performed with stitches compared to the ones performed without stitches. Methods. Our experimental model is based on ten piglets, which were divided into 2 groups. In the first group (n=5) the pancreatico-gastric anastomosis was done using double purse-string threads one passed through the gastric seromuscular layer and one through the gastric mucosa. In the
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19

Kovalevskii, A. D., and M. I. Prudkov. "Combined interventions on pancreatic ducts with external fistulas." Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery 28, no. 1 (2023): 97–103. http://dx.doi.org/10.16931/1995-5464.2023-1-97-103.

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The present paper describes clinical observation of successful treatment of a patient with chronic calcifying pancreatitis complicated by an external pancreatic fistula. Abdominal surgery after laparotomy and cholecystectomy had to be limited to bursoomentostomy due to the bleeding tissues and severe blood loss. Combined endoscopic intervention through the external pancreatic fistula was used for the treatment. The performed interventions included stone extraction in Wirsung’s duct, dilation and stenting of the distal stricture of the pancreatic duct. The fistula closed, a pain-free period las
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20

Mihai, Catalina, Mariana Floria, Radu Vulpoi, et al. "Pancreatico-Pleural Fistula – from Diagnosis to Management. A Case Report." Journal of Gastrointestinal and Liver Diseases 27, no. 4 (2018): 465–69. http://dx.doi.org/10.15403/jgld.2014.1121.274.ple.

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Pancreatic pseudocysts are frequent complications of both acute and chronic pancreatitis. By contrast, pancreatico-pleural fistula is rare. Here we report a case of massive pleural effusion secondary to a fistula in the left hemi-diaphragm, between a pancreatic pseudocyst and the left pleura, in a patient with a right kidney tumor and bilateral massive pulmonary thromboembolism. This fistula developed after several episodes of un-investigated acute pancreatitis. The pleural effusion was treated by three thoracocenteses, without recurrence.
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21

Andrey, Kriger, Gorin David, R. Kaldarov Ayrat, et al. "A RARE CASE OF CHRONIC PANCREATITIS COMPLICATED BY INTERNAL PANCREATIC FISTULA AND PANCREATOGENIC ASCITES." International Journal of Medical Reviews and Case Reports 2, no. 4 (2018): 115–18. https://doi.org/10.5455/IJMRCR.pancreatic-fistula.

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Objective: pancreatogenic ascites is rare complication of the chronic pancreatitis associated with a rupture in the ductal system and caused by internal pancreatic fistula. It can become as a result of the chronic pancreatitis, injury of the pancreas and stricture of the pancreatic duct. Case presentation: 40 years old male was admitted to our hospital suffered of surrounded epigastric pain, nausea, vomiting, enlargement of the abdomen, dyspnoea. Anamnesis showed that patient suffers of chronic calculous pancreatitis for 4 years, was hospitalized 8-9 times per year for conservative treatment.
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22

Tudor, A., VO Butiurca, C. Nicolescu, et al. "Pancreatico-gastric Anastomosis Following Cephalic Duodenopancreatectomy: New Perspectives." Acta Medica Marisiensis 61, no. 3 (2015): 172–75. http://dx.doi.org/10.1515/amma-2015-0058.

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Abstract Introduction. Although in recent years there have been various versions of pancreatic - digestive reconstruction after cephalic duodenopancreatectomy, this issue is still highly debated. Purpose. This paper aims at comparing postoperative outcomes after gastric pancreatic anastomosis using transfixing threads as opposed to the purse-string suture method. Material and methods. Our study consisted of a lot of 15 patients that underwent cephalic duodenopancreatectomy from the 1th of May 2014 to the 30th of April 2015. The pancreatico - digestive reconstruction was done by pancreatico-gas
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23

LUKASHEW, ANDREW D., SERGEY V. KUROCHKIN, MARAT R. TAGIROV, ELVIRA B. ZAKIROVA, and DENIS V. MAKAROV. "INTERNAL PANCREATIC FISTULA IN A PATIENT WITH ACUTE DESTRUCTIVE PANCREATITIS ASSOCIATED WITH SYSTEMIC CONNECTIVE TISSUE DISEASES." Bulletin of Contemporary Clinical Medicine 17, no. 6 (2024): 112–19. https://doi.org/10.20969/vskm.2024.17(6).112-119.

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Introduction. A pPancreatic fistula is an abnormal connection of pancreatic ductal epithelium with another epithelial surface. Pancreatic fistulas may occur as a complication of acute or chronic pancreatitis. The incidence of external and internal fistulas in the outcome of pancreatic necrosis ranges from 5 to 50%. Aim was to present for discussion a clinical case of a female patient with acute pancreatitis complicated by pseudocysts and an internal pancreatic fistula, associated with systemic connective tissue diseases, as well as the results of diagnosing and the treatment options chosen. Ma
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24

Sommer, Camille Anne, and C. Mel Wilcox. "Pancreatico-pericardial fistula as a complication of chronic pancreatitis." F1000Research 3 (January 29, 2014): 31. http://dx.doi.org/10.12688/f1000research.3-31.v1.

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Pancreatico-pericardial fistula is an extremely rare complication of chronic pancreatitis. We present a case of a 58-year-old man who presented with syncope. Transthoracic echocardiogram revealed a pericardial effusion with tamponade physiology. Pericardiocentesis and pericardial fluid analysis demonstrated a lipase level of 2321 U/L. Subsequently, an endoscopic retrograde cholangiopancreatography (ERCP) was performed, confirming the presence of a pancreatico-pericardial fistula (PPF) from the distal body of the pancreas. A pancreatic duct stent was placed across the duct disruption on two sep
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25

Kusnierz, Katarzyna, Slawomir Mrowiec, and Pawel Lampe. "A Comparison of Two Invagination Techniques for Pancreatojejunostomy after Pancreatoduodenectomy." Gastroenterology Research and Practice 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/894292.

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Background.The aim of the study was to compare two invagination techniques for pancreatojejunostomy after pancreatoduodenectomy.Methods.For effective prevention of the development of pancreatic leakage, we modified invagination technique that we term the “serous touch.” We analysed the diameter of the main pancreatic duct, the texture of the remnant pancreas, the method of the reconstruction, pancreatic external drainage, anastomotic procedure time, histopathological examination, and postoperative complications.Results.Fifty-two patients underwent pancreatoduodenectomy with pancreatojejunostom
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26

Munirathinam, Manoj, Pugazhendhi Thangavelu, and Ratnakar Kini. "Pancreatico‑pleural Fistula: Case Series." Journal of Digestive Endoscopy 09, no. 01 (2018): 026–31. http://dx.doi.org/10.4103/jde.jde_23_17.

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ABSTRACTPancreatico‑pleural fistula is a rare but serious complication of acute and chronic pancreatitis. The pleural effusion caused by pancreatico‑pleural fistula is usually massive and recurrent. It is predominately left‑sided but right‑sided and bilateral effusion does occur. We report four cases of pancreatico‑pleural fistula admitted to our hospital. Their clinical presentation and management aspects are discussed. Two patients were managed by pancreatic endotherapy and two patients were managed conservatively. All four patients improved symptomatically and were discharged and are on reg
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27

Salgado-Garza, Gustavo, Annika Willy, Flavio G. Rocha, Skye C. Mayo, Brett C. Sheppard, and Patrick J. Worth. "The VIPR-1 trial (Visualizing Ischemia in the Pancreatic Remnant): Assessing the role of intraoperative indocyanine green perfusion in predicting postoperative pancreatic leaks and fistulas: Protocol for a phase II clinical trial." PLOS One 20, no. 6 (2025): e0311025. https://doi.org/10.1371/journal.pone.0311025.

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Surgery of the pancreas has come a long way since its inception; however, postoperative morbidity is still high. Pancreatic leaks and fistulas are common complications in patients undergoing surgery to remove the pancreas. Fistulas delay subsequent oncological care after surgery and prolong the hospital stay. Hypoperfusion of the pancreas has been proposed as one factor leading to fistulas. Indocyanine green (ICG) injection allows the surgeon to evaluate blood perfusion to tissue in real-time. This protocol describes a trial that aims to assess the effectiveness of intraoperative ICG metrics o
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28

Ishizaki, Yoichi, Jiro Yoshimoto, Hiroyuki Sugo, Hiroshi Imamura, and Seiji Kawasaki. "Validation of Mucosal Sutureless Pancreatojejunostomy after Pancreatoduodenectomy." American Surgeon 80, no. 2 (2014): 149–54. http://dx.doi.org/10.1177/000313481408000222.

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Although duct-to-mucosa pancreatojejunostomy has been considered safer than other techniques, this procedure is particularly difficult when the pancreatic duct is small. It has therefore become increasingly necessary to develop a simple mucosal sutureless pancreatojejunostomy technique to replace the conventional hand-sewing one. Two hundred fourteen patients who underwent mucosal sutureless pancreatojejunostomy were classified into two groups: those with a normal pancreatic duct diameter (less than 3 mm, n = 97) and those with a dilated pancreatic duct (3 mm or greater, n = 117). The rate of
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29

Pedrazzoli, Sergio, Cosimo Sperti, and Claudio Pasquali. "An Easier Technique for End to End Pancreatlcojejunostomy." HPB Surgery 9, no. 3 (1996): 141–43. http://dx.doi.org/10.1155/1996/18087.

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Breakdown of the pancreaticoenterostomy is responsible for a number of complications and for the high mortality associated with pancreaticoduodenectomy. Although in recent years the postoperative mortality has dropped to less than 10% and in some to less than 5%, pancreatic fistula remains the most common and troublesome complication.Various procedures, such as duct ligation or occlusion, resection of the pancreatic stump or pancreaticogastrostomy, have been proposed to treat the pancreatic stump when it is considered unsuitable for jejunal anastomosis. A little trick permitted us to perform 4
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30

Desu, Bharath Kumar, Supreeth Kumar Reddy Kunnuru, Mayank Kumar Gurjar, et al. "A study on predictive factors for anastomotic leakage in enteropancreatic anastomosis in a tertiary centre in Andhra Pradesh." International Surgery Journal 6, no. 9 (2019): 3297. http://dx.doi.org/10.18203/2349-2902.isj20194069.

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Background: This study aimed to identify various factors influencing occurrence of post-operative pancreatic fistula.Methods: Only those patients who underwent standard pancreatojejunostomy anastomosis in duct to mucosa technique using vicryl 4-0 sutures (double layer- interrupted fashion) were included in the study. Patients who had duct size ≤3 mm underwent papillary like main pancreatic duct invaginated technique of pancreaticojejunostomy (fish mouth type).Results: In 40 patients, 10 patients (25%) developed postoperative pancreatic fistula. 5 (12.5%) patients had grade A pancreatic fistula
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31

Valikhnovska, K. G. "Pancreatic fistulae following pancreatic resection. Analysis of causes and prevention methods." Reports of Vinnytsia National Medical University 22, no. 4 (2018): 640–46. http://dx.doi.org/10.31393/reports-vnmedical-2018-22(4)-11.

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The causes of pancreatic fistula were analyzed in 503 patients aged from 22 to 81who underwent pancreaticoduodenectomy for pancreatic and periampullary tumors. The said patients were operated on during the period from 2008 to 2017. The aim of this study is to improve the outcomes of pancreatic resection based on a retrospective analysis of the risk factors of postoperative pancreatic fistulae and the development of a range of measures to prevent the above complication. The influence of factors on the risk of pancreatic fistula was investigated by Pearson method (χ2). The factors contributing t
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32

Garale, Mahadeo Namdeo, Yogesh Prabhakar Takalkar, and Karthik Venkatramani. "Clinical study of enterocutaneous fistula." International Surgery Journal 4, no. 9 (2017): 2972. http://dx.doi.org/10.18203/2349-2902.isj20173705.

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Background: An enterocutaneous fistulae (ECF) may be challenging to manage due to the large volume of fluid losses, that may result in severe dehydration, electrolyte imbalances, malnutrition and sepsis. It is imperative that this group of patients receive adequate nutrition, as malnutrition and sepsis are the leading cause of death.Methods: This descriptive study was conducted prospectively in the Department of Surgery between September 2004 and August 2010. Patients whom develop ECF after surgery were included in the study while patients with esophageal, biliary, pancreatic, and perianal fis
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33

Violi, Vincenzo, Carlo Salvemini, Antonio Darecchio, Paolo Detullio, and Renato Costi. "Pure Pancreaticocutaneous Fistula Shunted Into the Urinary Bladder. Lesson Learned by an Incomplete, Original Attempt." International Surgery 99, no. 3 (2014): 258–63. http://dx.doi.org/10.9738/intsurg-d-13-00110.1.

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Abstract Because pancreaticocystostomy is a method of exocrine secretion management in pancreas transplantation, a legitimate question is whether a pure pancreatic fistula could be shunted into the bladder. After duodenopancreatectomy for cancer, a pancreaticojejunostomy leakage was treated by pancreas-saving anastomosis disconnection. The resulting pure pancreaticocutaneous fistula was later diverted into the bladder using a Denver valved-pump device. Technical problems necessitated redoing the shunt using a modified technique and device. Although the system did work, catheter displacement ou
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Maeda, Koki, Naohisa Kuriyama, Yuki Nakagawa, et al. "Optimal management of peripancreatic fluid collection with postoperative pancreatic fistula after distal pancreatectomy: Significance of computed tomography values for predicting fluid infection." PLOS ONE 16, no. 11 (2021): e0259701. http://dx.doi.org/10.1371/journal.pone.0259701.

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Peripancreatic fluid collections have been observed in most patients with postoperative pancreatic fistula after distal pancreatectomy; however, optimal management remains unclear. This study aimed to evaluate the management and outcomes of patients with postoperative pancreatic fistula and verify the significance of computed tomography values for predicting peripancreatic fluid infections after distal pancreatectomy. We retrospectively investigated 259 consecutive patients who underwent distal pancreatectomy. Grade B postoperative pancreatic fistula patients were divided into two subgroups (B
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Warshaw, Andrew L. "Jejunum or Stomach for the Pancreatic Anastomosis After Pancreaticoduodenectomy." HPB Surgery 10, no. 3 (1997): 191–93. http://dx.doi.org/10.1155/1997/76467.

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Objective: The authors hypothesized that pancreaticogastrostomy is safer than pancreaticojejunostomy after pancreaticoduodenectomy and less likely to be associated with a postoperative pancreatic fistula.Summary Background Data: Pancreatic fistula is a leading cause of morbidity and mortality after pancreaticoduodenectomy, occurring in 10% to 20% of patients. Nonrandomized reports have suggested that pancreaticogastrostomy is less likely than pancreaticojejunostomy to be associated with postoperative complications.Methods: Between May 1993 and January 1995, the findings for 145 patients were a
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Nestler, Sebastian, Andreas Neisius, Frederik Roos, et al. "Pancreatic Fistulae after Urologic Surgery - A Single Centre Experience." Urologia Internationalis 95, no. 3 (2015): 346–51. http://dx.doi.org/10.1159/000381561.

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Introduction: To evaluate incidence, symptoms and management of postoperative pancreatic fistula (POPF) after urologic surgery based on our experience. Material and Methods: Database was searched for clinically evident POPF after urologic surgery between 1998 and 2014. Fistulae were graded using the POPF classification. Clinical course of every POPF patient was evaluated. Results: During this time, 3,200 surgeries for renal, adrenal and retroperitoneal pathologies were performed. Twelve POPF occurred postoperatively in this series. Eight fistulae were POPF grade A, 3 POPF grade B and one POPF
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Najafizadeh-Sari, Shahriar, Jamal A. Moghadam, Hamed Gholizadeh, et al. "Pyloric-preserving Pancreaticoduodenectomy with Duct to Mucosa Pancreatico-gastrostomy Reconstruction: Long-term Follow-up in a Tertiary Center." Romanian Journal of Military Medicine 127, no. 5 (2024): 375–80. http://dx.doi.org/10.55453/rjmm.2024.127.5.6.

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Background: Duct to mucosa Pancreatico-gastrostomy (DMPG) is a method for reconstruction of pancreatic mass following pancreaticoduodenectomy (PD). There are still controversies about the benefits of this surgical technique compared to the old ones. Objectives: This study aimed to evaluate the long-term outcomes of DMPG reconstruction following PD operation. Method: Through a prospective observational setting, 164 patients, undergoing PD surgery, with diagnosed pancreatic head or peri-ampullary cancer, were enrolled. A pylorus-preserving PD and DMPG were done for all patients to reconstruct th
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Remizov, S. I., A. V. Andreev, V. M. Durleshter, S. A. Gabriel’, and O. V. Zasyadko. "Principles of diagnosis and choice of treatment tactics for patients with pancreatic-pleural fistulas." Ural Medical Journal 22, no. 4 (2023): 11–17. http://dx.doi.org/10.52420/2071-5943-2023-22-4-11-17.

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Introduction. Pancreatic-pleural fistula is a rare complication of pancreatitis that has no pathognomonic symptoms and unified approaches to the choice of treatment tactics.The aim of the study was to formulate the principles of diagnosis and choice of treatment tactics in patients with pancreatic-pleural fistulas.Materials and methods. Five patients with pancreatic-pleural fistulas were treated from 2012 to 2022. All patients underwent standard clinical-laboratory and instrumental methods of investigation.Results. The diagnosis of pancreatic-pleural fistula was made at 18−65th day from the di
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Chabowski, Mariusz, Wiktor Pawlowski, Michał Lesniak, et al. "Successful postoperative pancreatic fistula treatment with the use of somatostatin infusion after duodenal gastrointestinal stromal tumor resection." Srpski arhiv za celokupno lekarstvo 147, no. 7-8 (2019): 484–87. http://dx.doi.org/10.2298/sarh180413053c.

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Introduction. According to the International Study Group on Pancreatic Fistula, a postoperative pancreatic fistula is defined as every case of fluid leak on the third (or later) postoperative day, in which the level of amylase in the collected fluid is at least three times higher than the serum amylase level. Depending on the stage and the designated management, pancreatic fistulas are divided into the following three categories: A (mild), B, and C (severe). Regardless of favorable conditions, exocrine pancreatic secretion is the key factor in fistula formation. The decrease in pancreatic secr
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Klein, Fritz, Igor Maximilian Sauer, Johann Pratschke, and Marcus Bahra. "Bovine Serum Albumin-Glutaraldehyde Sealed Fish-Mouth Closure of the Pancreatic Remnant during Distal Pancreatectomy." HPB Surgery 2017 (January 17, 2017): 1–7. http://dx.doi.org/10.1155/2017/9747421.

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Introduction. Postoperative pancreatic fistula formation remains the major complication after distal pancreatectomy. At our institution, we have recently developed a novel bovine serum albumin-glutaraldehyde sealed hand sutured fish-mouth closure technique of the pancreatic remnant during distal pancreatectomy. The aim of this study was to analyze the impact of this approach with regard to technical feasibility and overall postoperative outcome. Patients and Methods. 32 patients who underwent a bovine serum albumin-glutaraldehyde sealed hand sutured fish-mouth closure of the pancreatic remnant
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Sajika Dighe, Raju Shinde, Sangita Shinde, and Mohit Gupte. "A rare case of pancreaticopleural fistula patient presented in surgery OPD." International Journal of Research in Pharmaceutical Sciences 11, SPL4 (2020): 1329–32. http://dx.doi.org/10.26452/ijrps.v11ispl4.4301.

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Pancreatico-pleural fistula is rare and infrequent complication of commonly occurring chronic pancreatitis leading to an extra-peritoneal abnormal connection between the pancreatic system and pleural cavity. Diagnosis needs high-level clinical suspicion to avoid delay in the diagnosis as the patient presents with respiratory distress rather than any abdominal symptom and produces large quantities of pleural fluid intractable of pleural tapping or chest drain. Diagnosis of the fistula is clicked by elevated pleural fluid amylase. Various imaging options are available with their unique importanc
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Sheehan, Maureen K., Kimberly Beck, Steve Creech, Jack Pickleman, and Gerard V. Aranha. "Distal Pancreatectomy: Does the Method of Closure Influence Fistula Formation?" American Surgeon 68, no. 3 (2002): 264–68. http://dx.doi.org/10.1177/000313480206800309.

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The appropriate closure of the pancreatic remnant after distal pancreatectomy is still debated. Suture techniques, stapled closure, and pancreaticoenteric anastomosis all have their supporters. In this study we have reviewed our data from distal pancreatectomy to determine whether the type of remnant closure or underlying pathologic process had any relation to postoperative fistula formation. We performed a retrospective chart review of patients undergoing distal pancreatectomy at our institution between 1993 and 2001. The charts were reviewed for morbidity and mortality. These were then relat
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Коpchak, V. М., L. О. Pererva, О. V. Duvalko, et al. "The methods of prophylaxis of the morbidity occurrence after pancreatico-duodenal resection." Klinicheskaia khirurgiia 86, no. 5 (2019): 3–7. http://dx.doi.org/10.26779/2522-1396.2019.05.03.

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Objective. To elaborate the system of measures with objective of lowering of the occurrence rate for pancreatic fistula and severe complications after pancreaticoduodenal resection (PDR).
 Маterials and methods. Results of treatment was analyzed for 143 patients, to whom pancreaticoduodenal resection performed. In accordance to the scheme proposed, using elaborated scale of the risk for occurrence of postoperative pancreatic fistula, were operated 56 patients in 2017 - 2018 yrs (the main group). Comparative group consisted of 87 patients, operated in the clinic in 2015 - 2016 yrs without
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Malya, Fatma Umit, Mustafa Hasbahceci, Yunus Tasci, et al. "The Role of C-Reactive Protein in the Early Prediction of Serious Pancreatic Fistula Development after Pancreaticoduodenectomy." Gastroenterology Research and Practice 2018 (2018): 1–7. http://dx.doi.org/10.1155/2018/9157806.

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Introduction. Despite recent advances in surgical techniques, pancreatic fistulas are common. We aimed to determine the role of C-reactive protein in the prediction of clinically relevant fistula development. Materials and Methods. Data from patients who underwent pancreaticoduodenectomy between 2012 and 2015 is collected. Postoperative 1st, 3rd, and 5th day (POD1, POD3, and POD5) C-reactive protein (CRP) levels, postoperative pancreatic fistula (POPF) development, other complications, length of hospital stay, and mortality were recorded. Results. Of 117 patients, 43 patients (36.8%) developed
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Matsumoto, Ippei, Keiko Kamei, Shumpei Satoi, Takuya Nakai, and Yoshifumi Takeyama. "Pancreaticogastrostomy Prevents Postoperative Pancreatic Fistula of Portal Annular Pancreas During Pancreaticoduodenectomy." International Surgery 101, no. 11-12 (2016): 550–53. http://dx.doi.org/10.9738/intsurg-d-16-00044.1.

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Portal annular pancreas (PAP) is an asymptomatic congenital pancreatic anomaly in which the uncinate process of the pancreas extends and fuses to the dorsal surface of the body of the pancreas by surrounding the portal vein and or the superior mesenteric vein. During pancreaticoduonectomy (PD), the presence of PAP significantly increased risk for postoperative pancreatic fistula (POPF) because specific management of 2 pancreatic resection planes with 1 or 2 pancreatic ducts is required for pancreatico-intestinal reconstruction. To reduce the risk of POPF, a shift of the resection plain to the
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Kopchak, V. M., L. O. Pererva, V. O. Kropelnytskyi, V. V. Khanenko, P. A. Azadov, and Z. Y. Holobor. "Prevention strategies for reducing the incidence of postoperative pancreatic fistulas in patients following pancreatoduodenectomy." General Surgery, no. 2 (November 15, 2023): 8–15. http://dx.doi.org/10.30978/gs-2023-2-8.

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Objective — to design and implement a preventive approach aimed at reducing the incidence of postoperative pancreatic fistulas and other complications following pancreatoduodenectomy in patients diagnosed with cancer of the pancreatic head and periampullary region.
 Materials and methods. The present study involved the analysis of treatment outcomes for a cohort of 370 patients diagnosed with cancer of the pancreatic head and periampullary region who underwent pancreatoduodenectomy during the years 2015—2021. Between November 2018 and December 2021, a total of 141 patients were operated o
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Aimoto, Takayuki, and Eiji Uchida. "Postoperative Pancreatic Fistula after Pancreaticoduodenectomy: Toward "Zero Pancreatic Fistulas"." Nihon Ika Daigaku Igakkai Zasshi 5, no. 4 (2009): 193–201. http://dx.doi.org/10.1272/manms.5.193.

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Meierhofer, Clara, Reinhold Fuegger, Georg O. Spaun, et al. "Endoscopic Transmural Therapy of Pancreatic Fistulas in an Interdisciplinary Setting—A Retrospective Data Analysis." Journal of Clinical Medicine 12, no. 13 (2023): 4531. http://dx.doi.org/10.3390/jcm12134531.

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Pancreatic fistulas belong to the most feared complications after surgery on or near the pancreas, abdominal trauma, or severe pancreatitis. The majority occur in the setting of operative interventions and are called postoperative pancreatic fistulas (POPF). They can lead to various complications, including abscesses, delayed gastric emptying or hemorrhages with a significant impact on morbidity and mortality. Several risk factors have been identified, including smoking, high BMI, male gender, and age. Prophylactic measures and treatment options have been explored but with limited success. Thi
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Jiang, H., N. Liu, M. Zhang, L. Lu, R. Dou, and L. Qu. "A Randomized Trial on the Efficacy of Prophylactic Active Drainage in Prevention of Complications after Pancreaticoduodenectomy." Scandinavian Journal of Surgery 105, no. 4 (2016): 215–22. http://dx.doi.org/10.1177/1457496916665543.

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Background and Aims: This randomized controlled trial was conducted to examine whether prophylactic active drainage decreases morbidity associated with pancreati-coduodenectomy. Material and Methods: A prospective, randomized controlled trial was conducted between April 2010 and May 2015 when 160 consecutive patients following elective pancreaticoduodenectomy were randomized intraoperatively to either prophylactic active drainage group or conventional passive drainage group. The main objectives were the incidence of postoperative pancreatic fistula and the associated clinical outcomes. Results
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Shah, Devank, Rupesh Pokharna, Sudhir Maharshi, Kamleshkumar Sharma, and Prerak Maniar. "Pancreatitis, Polyarthritis and Panniculitis (PPP) Syndrome - A Rare Presentation." ACG Case Reports Journal 12, no. 2 (2025): e01601. https://doi.org/10.14309/crj.0000000000001601.

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ABSTRACT Pancreatitis, panniculitis, and polyarthritis (PPP) syndrome is a rare manifestation (prevalence 2%–3%) of underlying pancreatic pathology which is characterized by fat necrosis in subcutaneous tissue and joints. The widely accepted etiological hypothesis is systemic dissemination of pancreatic lipase. It has a mortality rate approaching 25%. We present a case of pancreatitis, panniculitis, and polyarthritis syndrome in a 52-year-old man with chronic pancreatitis complicated by pancreatico-pericardial fistula.
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