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Relevant bibliographies by topics / Flavanone Derivatives

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Academic literature on the topic 'Flavanone Derivatives'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Flavanone Derivatives"

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Poerwono, Hadi, and Marcellino Rudyanto. "Bibliometric Study of Microwave-Assisted Synthesis of Flavanone Derivatives." Borneo Journal of Pharmacy 6, no. 4 (2023): 339–48. http://dx.doi.org/10.33084/bjop.v6i4.5602.

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This study aims to describe various studies related to synthesizing flavanone derivatives using the microwave-assisted method with a bibliometric approach. Metadata information was collected from Scopus on June 30th, 2023, with three keywords (microwave-assisted OR microwave, synthesis, and flavanone) searched for article titles, abstracts, and keywords. Analysis and research mapping were carried out with VOSviewer. Of the 33 articles relevant for analysis, 15 keyword clusters were obtained, most of which contained a list of flavanone derivatives. Interestingly, none of these clusters contain

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Sinyeue, Cynthia, Mariko Matsui, Michael Oelgemöller, et al. "Synthesis and Investigation of Flavanone Derivatives as Potential New Anti-Inflammatory Agents." Molecules 27, no. 6 (2022): 1781. http://dx.doi.org/10.3390/molecules27061781.

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Flavonoids are polyphenols with broad known pharmacological properties. A series of 2,3-dihydroflavanone derivatives were thus synthesized and investigated for their anti-inflammatory activities. The target flavanones were prepared through cyclization of 2′-hydroxychalcone derivatives, the later obtained by Claisen–Schmidt condensation. Since nitric oxide (NO) represents an important inflammatory mediator, the effects of various flavanones on the NO production in the LPS-induced RAW 264.7 macrophage were assessed in vitro using the Griess test. The most active compounds were flavanone (4G), 2′

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Maciel Diogo, Gabriela, Josimara Souza Andrade, Policarpo Ademar Sales Junior, Silvane Maria Fonseca Murta, Viviane Martins Rebello Dos Santos, and Jason Guy Taylor. "Trypanocidal Activity of Flavanone Derivatives." Molecules 25, no. 2 (2020): 397. http://dx.doi.org/10.3390/molecules25020397.

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Chagas disease, also known as American trypanosomiasis, is classified as a neglected disease by the World Health Organization. For clinical treatment, only two drugs have been on the market, Benznidazole and Nifurtimox, both of which are recommended for use in the acute phase but present low cure rates in the chronic phase. Furthermore, strong side effects may result in discontinuation of this treatment. Faced with this situation, we report the synthesis and trypanocidal activity of 3-benzoyl-flavanones. Novel 3-benzoyl-flavanone derivatives were prepared in satisfactory yields in the 3-step s

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Kłósek, Małgorzata, Agnieszka Krawczyk-Łebek, Edyta Kostrzewa-Susłow, et al. "In Vitro Anti-Inflammatory Activity of Methyl Derivatives of Flavanone." Molecules 28, no. 23 (2023): 7837. http://dx.doi.org/10.3390/molecules28237837.

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Inflammation plays an important role in the immune defense against injury and infection agents. However, the inflammatory chronic process may lead to neurodegenerative diseases, atherosclerosis, inflammatory bowel diseases, or cancer. Flavanones present in citrus fruits exhibit biological activities, including anti-oxidative and anti-inflammatory properties. The beneficial effects of flavanones have been found based on in vitro cell cultures and animal studies. A suitable in vitro model for studying the inflammatory process are macrophages (RAW264.7 cell line) because, after stimulation using

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Felgines, Catherine, Odile Texier, Christine Morand, et al. "Bioavailability of the flavanone naringenin and its glycosides in rats." American Journal of Physiology-Gastrointestinal and Liver Physiology 279, no. 6 (2000): G1148—G1154. http://dx.doi.org/10.1152/ajpgi.2000.279.6.g1148.

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Naringenin, the predominant flavanone in grapefruit, mainly occurs as glycosides such as naringenin-7- rhamnoglucoside or naringenin-7-glucoside. This study compared kinetics of absorption of naringenin and its glycosides in rats either after a single flavanone-containing meal or after adaptation to a diet for 14 days. Regardless of the diet, circulating metabolites were glucurono- and sulfoconjugated derivatives of naringenin. The kinetics of absorption of naringenin and naringenin-7-glucoside were similar, whereas naringenin-7-rhamnoglucoside exhibited a delay in its intestinal absorption, r

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De, Surya K., Mrinal G. Dhara, and Asok K. Mallik. "Synthesis of trans-2,3-dimethoxy-3- (phenylamino)flavanones and related compounds." Canadian Journal of Chemistry 76, no. 2 (1998): 199–204. http://dx.doi.org/10.1139/v97-219.

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trans-2,3-Dimethoxy-3-(phenylamino)flavanones (2), a new type of flavanone derivatives, are synthesized from flavanones or 2'-hydroxychalcones in two steps, the first one being a condensation with nitrosobenzenes (Ehrlich-Sachs reaction) and the second an oxidation with (diacetoxyiodo)benzene in methanol. Nitrone formation, an important side reaction of the Ehrlich-Sachs reaction, has also been exploited to synthesize 2 simply by use of an excess of nitrosobenzene in aqueous methanol. Syntheses of several analogues of 2 are also reported.Key words: trans-2,3-dimethoxy-3-(phenylamino)flavanones

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Łodyga-Chruścińska, Elżbieta, Agnieszka Kowalska-Baron, Paulina Błazińska, et al. "Position Impact of Hydroxy Groups on Spectral, Acid–Base Profiles and DNA Interactions of Several Monohydroxy Flavanones." Molecules 24, no. 17 (2019): 3049. http://dx.doi.org/10.3390/molecules24173049.

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Structure-related biological activities of flavanones are still considered largely unexplored. Since they exhibit various medicinal activities, it is intriguing to enter deeper into their chemical structures, electronic transitions or interactions with some biomolecules in order to find properties that allow us to better understand their effects. Little information is available on biological activity of flavanone and its monohydroxy derivatives in relation to their physicochemical properties as spectral profiles, existence of protonated/deprotonated species under pH changes or interaction with

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Mottaghipisheh, Javad, and Marcello Iriti. "Sephadex® LH-20, Isolation, and Purification of Flavonoids from Plant Species: A Comprehensive Review." Molecules 25, no. 18 (2020): 4146. http://dx.doi.org/10.3390/molecules25184146.

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Flavonoids are considered one of the most diverse phenolic compounds possessing several valuable health benefits. The present study aimed at gathering all correlated reports, in which Sephadex® LH-20 (SLH) has been utilized as the final step to isolate or purify of flavonoid derivatives among all plant families. Overall, 189 flavonoids have been documented, while the majority were identified from the Asteraceae, Moraceae, and Poaceae families. Application of SLH has led to isolate 79 flavonols, 63 flavones, and 18 flavanones. Homoisoflavanoids, and proanthocyanidins have only been isolated fro

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Syah, Yana M., and Emilio L. Ghisalberti. "Flavanone derivatives from Macaranga tanarius." Biochemical Systematics and Ecology 62 (October 2015): 151–54. http://dx.doi.org/10.1016/j.bse.2015.08.009.

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Oganesyan, Eduard T., та Stanislav S. Shatokhin. "USING QUANTUM-CHEMICAL PARAMETERS FOR PREDICTING ANTI-RADICAL (НО∙) ACTIVITY OF RELATED STRUCTURES CONTAINING A CINNAMOYL FRAGMENT II. DERIVATIVES OF 2’,4’-DIHYDROXYCHALCONE, FLAVANONE AND FLAVONE, CONTAINING A HYDROXY GROUP IN POSITION 7". Pharmacy & Pharmacology 8, № 2 (2020): 112–23. http://dx.doi.org/10.19163/2307-9266-2020-8-2-112-123.

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42 derivatives of 2’,4’-dihydroxychalcone, flavanone and flavone, containing the hydroxy group in position 7 (ring "A"), as well as substituents in the ring "B", have been studied.The aim is to study the quantum-chemical parameters of 2',4'-dihydroxychalcone, flavanone and flavone derivatives containing a hydroxy group in position 7, in order to identify the effect of substituents on Mulliken charges (a.e) in the aromatic core "A", bond numbers (Nµ), the unsaturation index (IUA) and the electron density of the carbon atoms of the cinnamoyl fragment.Materials and methods. The listed above param

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Dissertations / Theses on the topic "Flavanone Derivatives"

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方顥伶. "One-Pot Synthesis of Bioactive Decahydroquinolines and Flavanone Derivatives Using Iodine as Catalyst." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/10554964013312880949.

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Chiou, Yi-Ling, and 邱翊玲. "Effects of flavanone derivatives and fenofibrate on melanogenesis in murine B16-F10 melanoma cells." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/38776993419825850819.

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碩士<br>靜宜大學<br>化粧品科學系碩士班<br>98<br>The color of mammalian skin and hair is determined by a number of factors, the most obvious phenotypical characteristics of which is the distribution of melanin pigment. Therefore, melanocytes act as important regulators for skin pigmentation and targets to study the mechanism of melanoma. In the present study, we investigated the action mechanisms of Citrus flavonoids and peroxisome proliferator-activated receptors (PPARs) activators on melanogenesis in B16-F10 melanoma cells. The most abundant Citrus flavonoids are flavanones, such as naringenin, naringin

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Passreiter, C. M., A.-K. Suckow-Schnitker, A. Kulawik, Jonathan A. Addae-Kyereme, Colin W. Wright, and W. Wätjen. "Prenylated flavanone derivatives isolated from Erythrina addisoniae are potent inducers of apoptotic cell death." 2015. http://hdl.handle.net/10454/7498.

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No<br>Extracts of Erythrina addisoniae are frequently used in the traditional medicine of Western Africa, but insufficient information about active compounds is available. From the stem bark of E. addisoniae, three (1, 2, 4) and three known (3, 5, 6) flavanones were isolated: addisoniaflavanones I and II, containing either a 2″,3″-epoxyprenyl moiety (1) or a 2″,3″-dihydroxyprenyl moiety (2) were shown to be highly toxic (MTT assay: EC50 values of 5.25 ± 0.7 and 8.5 ± 1.3 μM, respectively) to H4IIE hepatoma cells. The cytotoxic potential of the other isolated flavanones was weaker (range of EC5

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Liao, Wei-Ting, and 廖唯廷. "Synthesis of Flavanone Derivatives via Conjugate Addition of Chromones and Arylboronic Acids by Reusable Palladium Catalyst in Water." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/xh89a3.

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碩士<br>國立臺北科技大學<br>有機高分子研究所<br>105<br>Flavonoids and flavanones are privileged structural motifs in numerous nature products and pharmaceutical molecules that show a variety of biological activities. For example: anti-oxidation, anti-inflammatory, anti-bacterial, anti-cancer and so on. In this study, we developed a Pd(OAc)2/cationic 2,2’-bipyridyl-catalytic system to catalyzed conjugate addition of chromones and arylboronic acids forming flavanone derivatives using water as the reaction medium. In comparison with other published conditions, our reaction not only use water as the green solvent f

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Lien, Wan Chen, and 連婉媜. "The establishment of structure-permeation relationship: flavanones and benzoxazinone derivative as the examples." Thesis, 2019. http://ndltd.ncl.edu.tw/cgi-bin/gs32/gsweb.cgi/login?o=dnclcdr&s=id=%22107CGU05553012%22.&searchmode=basic.

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Chen, Po-Yuan, and 陳伯淵. "New syntheses of benzoheterocyclic derivatives: (i) flavanones; (ii) 2-substituted 3-benzylbenzofurans and (iii) 3,4-dihydroisoquinolin-1(2H)-ones." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/87931651625025683656.

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博士<br>高雄醫學大學<br>醫藥暨應用化學研究所<br>100<br>Chapter I Mild and environmentally benign methods for the syntheses of flavanones are described. The reaction of o-hydroxyacetophenones (I-1) and benzaldehydes (I-2) in water in the presence of DABCO at room temperature gave 3-hydroxy-1-(2-hydroxylphenyl)-3-arylpropan-1-ones (I-3a-i) as intermediates. Followed by an intramolecular dehydration of the 3a-i with the modified Mitsunobu’s reaction, the target flavanones (I-4a-i) were obtained. Moreover, the reaction of I-1 and I-2 at the same conditions but at reflux gave flavanones in one pot with good yields.

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Wu, Chao-Chin, and 吳朝欽. "1.Characterization of Flavones and Flavanones by Ion-Molecule Reactions/Collisionally Activated Dissociation in an External Source Ion Trap Mass Spectrometer 2.Characterization of Phthalic Anhydride and their derivatives by Electron Capture Detection/Coll." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/70810705469591265110.

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碩士<br>淡江大學<br>化學學系<br>87<br>2.Electron Capture Detection Mass Spectrometry is a sensitive and selective technique for the analysis of compounds containing electrophilic functional groups. It has been used extensively for the analysis of many classes of compounds in the traditional mass spectrometers but none was reported from the ion trap mass spectrometer since the traditional ion trap MS can not perform negative ion analysis. However, in this study we have examined a series of Phthalic anhydride and their derivatives by electron capture detection in the ion trap tandem mass spectr

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Book chapters on the topic "Flavanone Derivatives"

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Eshghi, Hossein, Mahsa Khoshnevis, and Fatemeh Pirani. "Recent Progress on Natural and Synthetic Flavanone and its Derivatives." In Frontiers in Natural Product Chemistry: Volume 9. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815040586122090009.

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Attia, Youssef A., Mohamed E. Abd El-Hack, Mahmoud M. Alagawany, et al. "Propolis." In Phytogenic and Phytochemical as Alternative Feed Additives for Animal Production. BENTHAM SCIENCE PUBLISHERS, 2025. https://doi.org/10.2174/9789815322767125010014.

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Propolis, a resinous substance collected by bees from plant exudates and buds, has gained renewed interest as a natural feed additive for animal nutrition. Its composition varies depending on the plant source, time, and place of collection; however, it is primarily composed of phenolic acids, flavonoids, and their derivatives. Egyptian propolis contains phenolic acid esters (72.7%), dihydrochalcones (6.5%), flavones (4.6%), aliphatic acids (2.4%), flavanones (1.9%), chalcones (1.7%), phenolic acids (1.1%), and tetrahydrofuran (THF) derivatives (0.7%). Turkish propolis contains flavonoids (37.8

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Rita Estevam, Maria, Estela Mesquita, and Magali Monteiro. "Phenolic Compounds Profile of Brazilian Commercial Orange Juice." In High Performance Liquid Chromatography - Recent Advances and Applications [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.109785.

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Orange juice is largely produced, exported and consumed in Brazil. It is an important source of bioactive compounds, such as flavonoids and phenolic acids, which are beneficial to the health of consumers. The aim of this work was to evaluate the phenolic compounds profile of commercial orange juice from Brazil using HPLC-DAD and UPLC-ESI-MS, and multivariate analysis. Forty-five phenolic compounds and one precursor were identified: cinnamic acid, 19 cinnamic acid derivatives, 8 flavanones and 18 flavones. Rutin, eriocitrin, narirutin, naringin, hesperidin, naringenin, nobiletin and tangeritin

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D’Ascenzio, Melissa. "The Role of Flavonoids and other Selected (Poly) Phenols in Cancer Prevention and Therapy: A Focus on Epigenetics." In Flavonoids and Phenolics. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815079098122010015.

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The importance of diet in determining the incidence of chronic illnesses such as diabetes, cardiovascular disorders, neurodegenerative diseases, and cancer has inspired extensive research on the role of individual dietary components in chemoprevention. Flavonoids and (poly)phenols have often been identified as the ideal candidates for these types of studies, as they represent large classes of natural products that are widely available in fruit and vegetables. In this chapter, we will discuss the antiproliferative properties of flavonols, flavanols, flavones, isoflavones, anthocyanins, curcumin

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Conference papers on the topic "Flavanone Derivatives"

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Marliyana, Soerya Dewi, Maulidan Firdaus, Muhamad Widyo Wartono, Diana Inas Utami, and Uly Wulan Apriani. "Evaluation of the Antibacterial Activity of Pinostrobin Derivative Compounds from Ethylation and Allylation Reactions." In 8th International Conference on Advanced Material for Better Future. Trans Tech Publications Ltd, 2025. https://doi.org/10.4028/p-s3ucax.

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Temu Kunci (Kaempferia pandurata Roxb.) is one of the plants from the Zingiberaceae family that contains secondary metabolites derived from flavonoids. Studies on the bioactivity of flavonoid compounds from this species have shown various biological activities such as antibacterial, antioxidant, antiviral, antitumor, antipyretic, anti-inflammatory, analgesic, and insecticidal properties. Pinostrobin (5-hydroxy-7-methoxy flavanone) (1) is the major flavonoid found in the rhizomes of this plant and has been successfully derivatized through ethylation and allylation reactions. Two compounds were

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Šaćirović, Sabina, Andrija Ćirić, Mališa Antić, and Zoran Marković. "HPLC ANALYSIS OF PHENOLS OF SLOVENIAN RED WINES: CABERNET SAUVIGNON AND MERLOT." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.165s.

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In this study, HPLC-DAD rapid analysis of phenols in wine samples was performed. The recording was performed at different wavelengths: phenolic acid (254nm), flavan-3-ols and stilbene (280nm), flavonoids (340nm) and anthocyanins (520nm). In selected wines, the concentrations of the following compounds were determined and expressed in mg/l of wine. The isolated derivatives were: hydroxybenzoic acids, derivatives of caffeic, ferulic, syringic, and vanillic acids, catechin (flavanol), rutin, myricetin and quercetin (flavonols), and the stilbene derivative-resveratrol. The properties and quantitie

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Peng, Han, and Fereidoon Shahidi. "Antioxidant activity of EGC (epigallocatechin) ester derivatives in food and biological model system." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/qchb4629.

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Objective: Antioxidants retard oxidative processes in food and pharmaceuticals as well as in the body. However, potential adverse effects of synthetic antioxidants and insufficient efficacy of current natural/natural-derived antioxidant substitutes necessitate developing novel antioxidants. Thus, EGC, as one of the most widely distributed dietary flavanols, serves as an efficient natural antioxidant with numerous health effects, but it is relatively poorly soluble in lipophilic media. In this study, novel lipophilic EGC derivatives prepared via enzymatic esterification will be evaluated in con

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