Academic literature on the topic 'Flinders Resistant Line rotte'

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Journal articles on the topic "Flinders Resistant Line rotte"

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Lillethorup, Thea Pinholt, Peter Iversen, Gregers Wegener, Doris Jeanne Marie Doudet та Anne Marlene Landau. "α2-adrenoceptor binding in Flinders-sensitive line compared with Flinders-resistant line and Sprague-Dawley rats". Acta Neuropsychiatrica 27, № 6 (2015): 345–52. http://dx.doi.org/10.1017/neu.2015.24.

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ObjectivesDisturbances in the noradrenergic system, including alterations in the densities of α2-adrenoceptors, are posited to be involved in the pathophysiology of depression. In this study, we investigate the binding of α2-adrenoceptors in regions relevant to depression in an animal model of depression.MethodsUsing in vitro autoradiography techniques and the selective α2-ligand, [3H]RX 821002, we investigated the density of α2-adrenoceptors in female Flinders-sensitive line (FSL) rats, a validated model of depression, and in two traditional control groups – female Flinders-resistant line (FR
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Matthews, Keith, Brian A. Baldo, Athina Markou, Olwen Lown, David H. Overstreet, and George F. Koob. "Rewarding electrical brain stimulation: Similar thresholds for flinders sensitve line hypercholinergic and flinders resistant line hypocholinergic rats." Physiology & Behavior 59, no. 6 (1996): 1155–62. http://dx.doi.org/10.1016/0031-9384(95)02212-0.

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Mattsson, Hillevi, Zahra Arani, Alfred Bayati, Claes Ekman, David H. Overstreet, and Maria Astin. "Flinders sensitive line (FSL) rats have increased gastric accommodation capacity compared to flinders resistant line (FRL) and sprague dawley (SD) rats." Gastroenterology 124, no. 4 (2003): A677. http://dx.doi.org/10.1016/s0016-5085(03)83431-5.

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Janssen, L. J., V. J. Djuric, J. Wattie, J. Otis, and P. M. O'Byrne. "In Vitro Airway Responsiveness of Flinders Sensitive and Resistant Line Rats." Brain, Behavior, and Immunity 14, no. 1 (2000): 62–67. http://dx.doi.org/10.1006/brbi.1999.0573.

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Ferreira-Nuño, A., D. H. Overstreet, A. Morales-Otal, and J. Velázquez-Moctezuma. "Masculine sexual behavior features in the Flinders sensitive and resistant line rats." Behavioural Brain Research 128, no. 2 (2002): 113–19. http://dx.doi.org/10.1016/s0166-4328(01)00313-8.

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Friedman, E. "Natural and Cellular Immune Responses in Flinders Sensitive and Resistant Line Rats." Neuropsychopharmacology 15, no. 3 (1996): 314–22. http://dx.doi.org/10.1016/0893-133x(95)00235-6.

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Jefsen, Oskar, Kristoffer Højgaard, Sofie Laage Christiansen, et al. "Psilocybin lacks antidepressant-like effect in the Flinders Sensitive Line rat." Acta Neuropsychiatrica 31, no. 04 (2019): 213–19. http://dx.doi.org/10.1017/neu.2019.15.

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AbstractObjective:Psilocybin is a serotonin receptor agonist with a therapeutic potential for treatment-resistant depression and other psychiatric illnesses. We investigated whether the administration of psilocybin had an antidepressant-like effect in a rat model of depression.Methods:Using the Flinders Sensitive Line (FSL) rat model of depression, we assessed the antidepressant-like effect of psilocin and psilocybin, measured as a reduction in immobility time in the forced swim test (FST). We measured locomotor activity in an open field test (OFT) to control for stimulant properties of the dr
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Zambello, Erika, Patricia A. Jiménez-Vasquez, Aram El Khoury, Aleksander A. Mathé, and Laura Caberlotto. "Acute stress differentially affects corticotropin-releasing hormone mRNA expression in the central amygdala of the “depressed” flinders sensitive line and the control flinders resistant line rats." Progress in Neuro-Psychopharmacology and Biological Psychiatry 32, no. 3 (2008): 651–61. http://dx.doi.org/10.1016/j.pnpbp.2007.11.008.

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Liu, Xi-Cong, Sophie Erhardt, Michel Goiny, Göran Engberg, and Aleksander A. Mathé. "Decreased levels of kynurenic acid in prefrontal cortex in a genetic animal model of depression." Acta Neuropsychiatrica 29, no. 1 (2016): 54–58. http://dx.doi.org/10.1017/neu.2016.31.

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ObjectiveThere is a growing interest in the role of kynurenine pathway and tryptophan metabolites in the pathophysiology of depression. In the present study, the metabolism of tryptophan along the kynurenine pathway was analysed in a rat model of depression.MethodsKynurenic acid (KYNA) and 3-hydroxykynurenine (3-HK) were measured by high-performance liquid chromatography (HPLC) in prefrontal cortex (PFC) and frontal cortex (FC) in a rat model of depression, the Flinders Sensitive Line (FSL) and their controls, the Flinders Resistant Line (FRL) rats. In addition, KYNA was also measured in hippo
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Kanemaru, Kazuya, and Mirko Diksic. "The Flinders Sensitive Line of rats, a rat model of depression, has elevated brain glucose utilization when compared to normal rats and the Flinders Resistant Line of rats." Neurochemistry International 55, no. 7 (2009): 655–61. http://dx.doi.org/10.1016/j.neuint.2009.06.011.

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Dissertations / Theses on the topic "Flinders Resistant Line rotte"

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Visser, Gert Petrus. "Cortical brain release of glutamate by ketamine and fluoxetine : an in vivo microdialysis study in the Flinders sensitive line rat / Gert Petrus Visser." Thesis, North-West University, 2012. http://hdl.handle.net/10394/9249.

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In vivo intracranial microdialysis is a valuable technique yielding novel and useful insight into normal or pathological neurochemical processes in the brain by means of sampling of interstitial fluid of cells in a living animal. It's most important advantage is that it can continuously monitor time-related changes in the concentration of neurotransmitters and their metabolites, other neuromodulators, energy substrates, as well as exogenous drugs in the extracellular fluid of specific brain areas of interest. While the development and standardization of the intracranial microdialysis technique
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Mouton, Moné. "The long-term effects of methamphetamine on depressive-like behaviour and neuroplasticity in stress-sensitive rats / Moné Mouton." Thesis, 2014. http://hdl.handle.net/10394/16313.

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Methamphetamine (METH) abuse has become a fast growing drug problem that has developed into a global epidemic. In fact, METH is one of the most commonly abused substances with an estimated 35 million abusers worldwide and is said to be the second most popular illicit drug. The Western Province of South Africa has seen a dramatic increase in drug abuse in recent years where METH is the primary or secondary drug of abuse. Interestingly, more than 50% of these individuals are under the age of 20 years. The longer duration of euphoric effects of METH has attracted many users away from cocaine in f
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