Academic literature on the topic 'Floating controlled drug delivery system'

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Journal articles on the topic "Floating controlled drug delivery system"

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Thakur, Sanjay, Krishnappa Ramya, Deepak Kumar Shah, and Khadga Raj. "Floating Drug Delivery System." Journal of Drug Delivery and Therapeutics 11, no. 3-S (2021): 125–30. http://dx.doi.org/10.22270/jddt.v11i3-s.4828.

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Floating drug delivery system (FDDS) helps to improve the buoyancy property of the drug over the gastric fluids and hence maintain the longer duration of action. It is helpful in minimizing the dosing frequency. The density of dosage form must be less than the density of gastric contents (1.004 gm/ml) in FDDS. It may effervescent or non-effervescent system. The drugs having narrow absorption window in GIT is good candidate for the floating drug delivery system. The main objective of writing this review article is to compile the recent literature with special focus on classification, method of
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G., Yashavanth, Prakash S. Goudanavar, and Mallamma T. "FLOATING DRUG DELIVERY SYSTEM: A REVIEW." International Journal of Advanced Research 10, no. 11 (2022): 161–67. http://dx.doi.org/10.21474/ijar01/15653.

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Recent technological and scientific research has been devoted to the development of rate-controlled drug delivery system to overcome physiological adversities such as unpredictable gastric emptying times and gastric residence time. FDDS are of particular interest of drugs that are locally active and have narrow absorption window in stomach. FDDS offers numerous advantages, specially the drugs having narrow absorption window in GIT, primary absorption in the stomach, Prolonged gastric retention improves bioavailability, reduces drug waste, and improves solubility for drugs that are least solubl
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Aman Shukla, Deepika Joshi, Bhavana Singh, and Nidhi Semwal. "Floating microspheres: Emerging delivery system for diabetes mellitus." World Journal of Biology Pharmacy and Health Sciences 11, no. 3 (2022): 026–35. http://dx.doi.org/10.30574/wjbphs.2022.11.3.0121.

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In order to increase bioavailability, stability, and target the drug to a specific region at a predetermined rate, floating microspheres, multi-unit drug delivery systems, are designed to accomplish controlled or delayed drug administration. In clinical practise, drugs that have an upper small intestine absorption window may benefit the most from a controlled drug delivery system with an extended stomach residence period. The non-uniformity of medication absorption throughout the gastrointestinal tract and the heterogeneity of gastrointestinal (GI) transit time across and among subjects are th
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Aman, Shukla, Joshi Deepika, Singh Bhavana, and Semwal Nidhi. "Floating microspheres: Emerging delivery system for diabetes mellitus." World Journal of Biology Pharmacy and Health Sciences 11, no. 3 (2022): 026–32. https://doi.org/10.5281/zenodo.7181330.

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In order to increase bioavailability, stability, and target the drug to a specific region at a predetermined rate, floating microspheres, multi-unit drug delivery systems, are designed to accomplish controlled or delayed drug administration. In clinical practise, drugs that have an upper small intestine absorption window may benefit the most from a controlled drug delivery system with an extended stomach residence period. The non-uniformity of medication absorption throughout the gastrointestinal tract and the heterogeneity of gastrointestinal (GI) transit time across and among subjects are th
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chilukala, Swathi. "Gastro retentive Drug Delivery of Cyclobenzaprine Hydrochloride." Gastroenterology Pancreatology and Hepatobilary Disorders 2, no. 1 (2018): 01–03. http://dx.doi.org/10.31579/2641-5194/006.

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Drugs that are easily absorbed from the GI tract and have a short half-life are eliminated quickly from the blood circulation, require frequent dosing. To avoid this problem, the oral controlled release formulations are being developed. Gastro-retentive dosage forms have the potential from use as controlled release systems. The purpose of this research is to develop the gastro retentive drug delivery system of centrally acting alpha adrenergic agonist cyclobenzaprine Hydrochloride (cyclobenzaprine HCl). It is well absorbed from the upper part of the GIT, due to short gastric residence time the
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Fu, Kai, Yifei Zhou, Jia Hou, et al. "Floating poly(lactic-co-glycolic acid)-based controlled-release drug delivery system for intravesical instillation." Journal of International Medical Research 51, no. 4 (2023): 030006052311620. http://dx.doi.org/10.1177/03000605231162065.

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Objectives To investigate the floating, structural, and controlled-release characteristics of a floating poly(lactic-co-glycolic acid) (PLGA)-based controlled-release drug delivery system, and determine the feasibility of this drug delivery system for intravesical instillation. Methods PLGA was dissolved in dimethylacetamide, then mixed with IR780 and doxorubicin (DOX) to prepare a drug delivery system capable of solidification and flotation on water at room temperature. Preparations of PLGA, PLGA+IR780, PLGA+DOX, and PLGA+IR780+DOX were formulated. Their floating characteristics in vivo and i
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panwar, Asha, Sakshi Singh, and Dr Himadri Dr. Himadri. "A Review on Formulation Development of Bilayer Floating Tablet." International Journal of Pharmaceutical Research and Applications 10, no. 1 (2025): 1406–10. https://doi.org/10.35629/4494-100114061410.

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In the recent past, controlled release concept and technology have received increasing attention in the face of growing awareness to toxicity and ineffectiveness of drugs when administered or applied by conventional methods. Thus drugs applied in the form of tablets, capsules, injectables and ointments etc., usually produce wide range of fluctuations in drug concentration in the blood stream and tissues with consequent undesirable toxicity and poor efficiency. This factor as well such as repetitive dosing and unpredictable absorption led to the concept of controlled drug delivery systems or th
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Choudhary, Mahima, Chanchal Tiwari, Rajeev Kumar Chahar, Princy Malik, PANKAJ KUMAR JAISWAL, and Reetu Chauhan. "Floating Drug Delivery System: As A Novel Approach for Drug Delivery." Journal of Drug Delivery and Therapeutics 12, no. 6 (2022): 210–18. http://dx.doi.org/10.22270/jddt.v12i6.5778.

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The retention period of the drug and dosage form in the stomach is very challenging for the treatment of gastrointestinal disease. To solve this problem and improve the efficacy and bioavailability of the drug, most researchers develop a novel carrier system that is called a Floating drug delivery system (FDDS). The goal of this review on floating drug delivery systems (FDDS) is to synthesise contemporary material with a particular concentration on the main mechanism of flotation for stomach retention. The physiology of the stomach (including gastric pH and movement) has been shown a major eff
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Mayur, Aware, Gondkar Sheetal, and Bachhav Rishikesh. "Bilayer Floating Tablet : A Novel Floating Tablet." International Journal in Pharmaceutical Sciences 1, no. 1 (2022): 86–93. https://doi.org/10.5281/zenodo.5895074.

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Out of various drug delivery system the novel drug delivery system is overcomes and then physiological problems of gastric retention by decreasing fluctuations in blood drug concentration level with consequent reduction in the undesirable toxicity and poor efficiency. Approaches have their been introduced to prolong gastric residence time such as the floating system, modified shape, swelling index, expanding system and high density system. Two layer floating drug delivery system is combined principle of bilayer tablet as well as floating mechanism. Bilayer floating tablet is new in the era for
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Pant, Shailaja, Ashutosh Badola, and Preeti Kothiyal. "A review on gastroretentive drug delivery system." Indian Journal of Pharmaceutical and Biological Research 4, no. 2 (2016): 01–10. http://dx.doi.org/10.30750/ijpbr.4.2.1.

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Oral controlled release and site specific drug delivery system has been of great interest in pharmaceutical field to achieve improved therapeutic advantage. Concept of novel drug delivery system arose to overcome certain aspect related to physicochemical properties of drug molecule and the related formulations. Gastro retentive drug delivery system is one of such novel approaches to prolong gastric residence time, thereby targeting site specific drug release in the stomach for local or systemic effects. This approach is useful particularly for the drugs which have narrow absorption window in t
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Dissertations / Theses on the topic "Floating controlled drug delivery system"

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Samaligy, Samar el [Verfasser]. "Floating Systems for Oral Controlled Release Drug Delivery / Samar El Samaligy." Berlin : Freie Universität Berlin, 2010. http://d-nb.info/1024784614/34.

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Lee, Yan Sim. "The development of controlled-chemotherapy drug delivery system." Thesis, University of Bath, 2009. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.512304.

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The aim of this thesis was to develop biodegradable devices loaded with chemotherapy drug. The system is targeted for advanced ovarian cancer treatment through the intraperitoneal (IP) route of administration. Polylactide-co-glycolide (PLGA) was selected as the model biodegradable polymer to produce drug-loaded microsphere, hollow and solid fibres. Copolymer PLGA with three different lactic:glycolic acids ratios; 50:50, 65:35 and 75:25 were used in order to compare their drug loading capacities and in vitro drug release profiles. Cisplatin, a cytotoxic drug with proven activity against ovarian
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Goettsche, Thorsten [Verfasser], Roland [Akademischer Betreuer] Zengerle, and Gerald A. [Akademischer Betreuer] Urban. "IntelliDrug - controlled, oral drug delivery system as tooth implant." Freiburg : Universität, 2016. http://d-nb.info/1128574195/34.

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Feely, L. C. "Controlled release hydroxypropylmethylcellulose mini-matrices." Thesis, University of Nottingham, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.373348.

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Babu, Kavitha Mary Vadakkel. "The Development of a Novel Controlled Release Drug Delivery System." The University of Waikato, 2007. http://hdl.handle.net/10289/2590.

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The aim of this research was to formulate, characterise and assess the feasibility of a novel drug delivery system known as the in situ gelling matrix (ISGM) where a hydrophilic polymer is suspended in a non-aqueous solvent that converts into a gel when injected subcutaneously or intramuscularly thus giving a controlled release matrix for a drug. Although the concept has been patented with claims that this kind of drug delivery is achievable in theory for a wide variety of candidate substances, actual formulation studies for making a commercially viable product for this technology are complet
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Rodriguez, Lidia Betsabe. "Controlled Release System for Localized and Sustained Drug Delivery Applications." University of Toledo / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1365107103.

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Zhuk, Mikalai. "Nanostructured granules for controlled delivery of dexamethasone." Master's thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/14181.

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Mestrado em Ciência e Engenharia de Materiais<br>A Drug Delivery System (DDS) may provide the precise transportation of the medical drug inside the patient’s body, directly to the pathological area or alternatively it may be also locally administrated. Once at the site of interest, the ideal DDS is expected to release the drug in a sustained manner according to the specific needs of the patient. As compared to other routes of drug administration, an appropriately designed DDS which active components are conveniently targeted should also ensure the desired in situ treatment without harmful effe
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Krishnan, Aadithya. "SIMVASTATIN INCORPORATED PERIVASCULAR POLYMERIC CONTROLLED DRUG DELIVERY SYSTEM FOR THE INHIBITION OF VASCULAR WALL INTIMAL HYPERPLASIA." University of Akron / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=akron1186425531.

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Tait, C. J. "A study of the properties of a poly(oxyethylene)-poly(oxypropylene)- poly(oxyethylene) block copolymer as a controlled release drug delivery system." Thesis, University of Manchester, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379172.

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De, la Torre Paredes Cristina. "Nanotechnology and supramolecular chemistry in controlled release and molecular recognition proceses for biomedical applications"." Doctoral thesis, Universitat Politècnica de València, 2018. http://hdl.handle.net/10251/94043.

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La presente tesis doctoral, titulada "Nanotecnología y química supramolecular en procesos de liberación controlada y reconocimiento molecular para aplicaciones biomédicas", se centra en dos temas importantes: el reconocimiento molecular y los procesos de liberación controlada. Esta tesis doctoral está estructurada en cuatro capítulos. El primer capítulo introduce el concepto de materiales híbridos orgánicos-inorgánicos funcionalizados con puertas moleculares y sus aplicaciones biomédicas como nanomateriales para dirigir y controlar la liberación controlada de fármacos. Además se introduce
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Books on the topic "Floating controlled drug delivery system"

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Frost & Sullivan., ed. Programmed drug delivery system markets. Frost & Sullivan, 1988.

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Frost & Sullivan., ed. U.S. fluid and drug delivery system markets: Annual update identifies market hot spots. Frost & Sullivan, 1994.

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Mangukia, Dhruv. Transdermal Drug Delivery System: Formulation and Evaluation of Matrix Diffusion Controlled Transdermal Patch of Glipizide. LAP Lambert Academic Publishing, 2012.

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Book chapters on the topic "Floating controlled drug delivery system"

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Pillai, Akhilraj, Dhanashree Bhande, and Vinal Pardhi. "Controlled Drug Delivery System." In Studies in Mechanobiology, Tissue Engineering and Biomaterials. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-6564-9_11.

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Jain, Surendra K., Aristide Laurel Mokale Kognou, Deepti Jain, Vinod Dhote, and Rajesh Singh Pawar. "Chemical Drug Delivery System." In Novel Carrier Systems for Targeted and Controlled Drug Delivery. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-4970-6_12.

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Kumar, Amit, Kashid Saurabh Machhindra, Keerti Jain, and Awesh K. Yadav. "Transdermal Drug Delivery System." In Novel Carrier Systems for Targeted and Controlled Drug Delivery. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-4970-6_5.

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Upadhyay, S., S. Soni, T. Shukla, et al. "Implantable Drug Delivery System." In Novel Carrier Systems for Targeted and Controlled Drug Delivery. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-4970-6_6.

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Sakagami, Masahiro, and Mark Gumbleton. "Targeted Drug Delivery Through the Respiratory System: Molecular Control on Lung Absorption and Disposition." In Controlled Pulmonary Drug Delivery. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-9745-6_6.

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Urquhart, John. "The Therapeutic System: Therapeutic Implications of Rate-Controlled Drug Delivery." In Directed Drug Delivery. Humana Press, 1985. http://dx.doi.org/10.1007/978-1-4612-5186-6_4.

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Pandey, Dheeraj, Neelam Gupta, Awesh Yadav, and Abha Sharma. "Protein/Peptides Drug Delivery System." In Novel Carrier Systems for Targeted and Controlled Drug Delivery. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-4970-6_7.

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Pandey, Shikha, Puja Nayak, Akanksha Malaiya, et al. "Colloidal Drug Delivery System: An Overview." In Novel Carrier Systems for Targeted and Controlled Drug Delivery. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-4970-6_15.

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Stegemann, Sven. "Capsules as a Delivery System for Modified-Release Products." In Controlled Release in Oral Drug Delivery. Springer US, 2011. http://dx.doi.org/10.1007/978-1-4614-1004-1_14.

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Shilpi, Satish, Khyati Saini, Pranali Chimaniya, et al. "Stimuli-Responsive Drug Delivery Systems: Magnetically, Thermally and pH Assisted Drug Delivery System." In Novel Carrier Systems for Targeted and Controlled Drug Delivery. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-4970-6_17.

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Conference papers on the topic "Floating controlled drug delivery system"

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Batista, Daniel V., and Marco S. Reis. "Balancing modelling complexity and experimental effort for conducting QbD on lipid nanoparticles (LNPs) systems." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.163183.

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The promising properties of lipid nanoparticles (LNPs) as drug carriers have been attracting significant attention in the field of drug delivery. However, further research is still required for a better understanding of their integration in the pharmaceutical industry. The Quality by Design (QbD) approach aims at ensuring the safety and efficiency in the development of new drugs, through an holistic, risk-based approach that gathers all sources of knowledge available about the system under analysis. One key resource of the QbD framework is the rich toolkit of Design of Experiments (DOE), to de
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Demina, P. A., N. V. Sholina, R. A. Akasov, et al. "Multimodal upconversion nanoparticles with controlled drug release as drug delivery system." In 2020 International Conference Laser Optics (ICLO). IEEE, 2020. http://dx.doi.org/10.1109/iclo48556.2020.9285550.

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Maloney, John M. "An Implantable Microfabricated Drug Delivery System." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-43186.

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We report on the development of a fully implantable drug delivery system capable of delivering hundreds of individual doses. This product is intended for the controlled release of potent therapeutic compounds that might otherwise require frequent injections. Our system has the following capabilities: • Stable, hermetic storage of therapeutic drugs in solid, liquid, or gel form; • Individual storage of discrete doses for multiple-drug regimens; • Wireless communication with an external controller for device monitoring and therapy modification; • Choice of preprogrammed release or release on com
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Ratnayake, W. R. A. P. J., J. W. Damunupola, S. Rajapakse, and A. C. A. Jayasundera. "Nanocellulose-Protein Matrices: A Model System for Controlled Drug Delivery." In International Conference on Nano Science and Nano Technology. The International Institute of Knowledge Management (TIIKM), 2018. http://dx.doi.org/10.17501/23861215.2018.5101.

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Wang, Xiaopeng, Tianning Chen, Zhanxiao Yang, and Wanjun Wang. "Design of controlled drug delivery system with optimal release characteristics." In MOEMS-MEMS 2006 Micro and Nanofabrication, edited by Ian Papautsky and Wanjun Wang. SPIE, 2006. http://dx.doi.org/10.1117/12.644077.

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Talbi, Yassine, Damien Brulin, Eric Campo, and Jean-Yves Fourniols. "Controlled Permeation of Lidocaine Hydrochloride Using a Smart Drug Delivery System." In Biomedical Engineering. ACTAPRESS, 2017. http://dx.doi.org/10.2316/p.2017.852-024.

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Chude-Okonkwo, Uche A. K. "Diffusion-controlled enzyme-catalyzed molecular communication system for targeted drug delivery." In GLOBECOM 2014 - 2014 IEEE Global Communications Conference. IEEE, 2014. http://dx.doi.org/10.1109/glocom.2014.7037236.

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Krishnamoorthy, G., P. Stephen, M. Prabhu, et al. "Collagen Coated Nanoliposome as a Targeted and Controlled Drug Delivery System." In INTERNATIONAL CONFERENCE ON ADVANCED NANOMATERIALS AND NANOTECHNOLOGY (ICANN-2009). AIP, 2010. http://dx.doi.org/10.1063/1.3504292.

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Blanco, Letia, Panos S. Shiakolas, Pranesh B. Aswath, et al. "A Thermoresponsive Hydrogel Based Controlled Drug Delivery Device." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-88564.

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Thermoresponsive hydrogels exhibit the unique property of volume change as a function of change in temperature as they transition between hydrophilic and hydrophobic states. These hydrogels can be loaded with drug/protein and serve as reservoirs for drug/protein delivery applications. A hydrogel based device for controlled drug delivery is designed with a number of subsystems that are interfaced with LabVIEW for development of a functional device. The device was designed using analytical and finite element analysis procedures and fabricated. In this manuscript, the device design will be review
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Dardano, P., I. Rea, L. De Stefano, A. Calio, and J. Politi. "Optically Controlled Drug Delivery System based on Porous Silicon and Microneedles patch." In 2015 1st Workshop on Nanotechnology in Instrumentation and Measurement (NANOFIM). IEEE, 2015. http://dx.doi.org/10.1109/nanofim.2015.8425359.

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Reports on the topic "Floating controlled drug delivery system"

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Sirivat, Anuvat. Electrically controlled release of drugs from alginate hydrogels for transdermal drug delivery application. Chulalongkorn University, 2014. https://doi.org/10.58837/chula.res.2014.80.

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A drug-loaded conductive polymer/hydrogel blend, benzoic acid-loaded poly(3,4-ethylenedioxythiophene/alginate (BA-loaded PEDOT/Alg) hydrogel, was used as a carrier/matrix for an electrical stimuli transdermal drug delivery system (TDDS). The effects of crosslinking ratio, PEDOT particle size, and electric field strength on the release mechanism and the diffusion coefficient (D) of BA were examined by using a modified Franz-diffusion cell. The diffusion scaling exponent value of BA is close to 0.5 which refers to the diffusion controlled mechanism, or the Fickian diffusion as the BA release mec
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Chutimaworapan, Suchada, Chaiyo Chaichantippayuth, and Areerat Laopaksa. Formulation of pharmaceutical products of Garcinia mangostana Linn. extracts. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.32.

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Part I: The purpose of the investigation was to develop the extraction process that was simple, practical and giving high yield. The maceration of dried powder of Garcinia mangostana fruit husk with ethyl acetate gave yellow crystalline powder of mangostin. The yield was calculated as 7.47%. The identification of the Garcinia mangostanahusk extract was carried out by thin-layer chromatography (TLC) and differential scanning calorimetry. The TLC of mangostin was done by using the alumina sheet and ethyl acetate: hexane (3:1) as mobile phase. The Rf value as compared with standard mangostin was
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