Relevant bibliographies by topics / Floating lag time

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Floating lag time'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Floating lag time"

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Mohammad, Rafivulla, Saketh Darisi, Pushpanjali Chowtipalli, Yohan Gangolu, Meghamala Gajula, and Rao Vadapalli* Rama. "A REVIEW OF THE ANALYSIS OF ANTIHISTAMINE MEDICATION FLOATING TIMES FOR EFFICIENCY EVALUATION." World Journal of Pharmaceutical Science and Research 3, no. 6 (2024): 68–80. https://doi.org/10.5281/zenodo.14252479.

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The purpose of a gastroretentive drug delivery system (GRDDS) is to increase drug absorption and bioavailability by extending the period of time that pharmaceuticals are in the stomach. This technique is especially helpful for medications with upper absorption windows digestive system or those that break down in the stomach's acidic environment. GRDDS can decrease dosage frequency and enhance therapeutic effects by prolonging a drug's gastrointestinal half-life.This review demonstrates a correlation between diminishing floating capabilities and the stomach residence time of antihistamine medic
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Darisi, Saketh1 Gangolu Yohan2 Gurram Lokeswari3 Bodapati Meghana4 Jayanth Kandula5 Dr. Rama Rao Vadapalli6*. "Analyzing Antihypertensive Drugs Floating Times for Efficiency Evaluation: A Review." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 1801–15. https://doi.org/10.5281/zenodo.15049315.

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Objective: This review aims to evaluate the efficacy of Gastroretentive Drug Delivery Systems (GRDDS) in enhancing the gastric residence time of antihypertensive drugs to improve drug absorption and bioavailability. Methods: The study analyzed various GRDDS formulations designed to prolong gastric residence time. Key parameters such as Total Floating Time and Floating Lag Time were measured to assess the sustained release capabilities of these formulations. A comparative analysis was conducted across different antihypertensive drugs, focusing on their floating capacities in simulated gastric f
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Aisiyah, Siti, Achmad Fudholi, and Abdul Rohman. "Optimasi Formula Tablet Floating Nifedipin Menggunakan HPMC K15M, PVP K-30 dan Avicel PH 102 dengan Metode Simplex Lattice Design." Jurnal Farmasi (Journal of Pharmacy) 2, no. 1 (2019): 30. http://dx.doi.org/10.37013/jf.v2i1.17.

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Nifedipin merupakan obat dengan kelarutan kecil dalam air sehingga kelarutan nifedipin perlu ditingkatkan dengan penambahan PVP K-30. Penelitian ini bertujuan untuk mengetahui pengaruh HPMC K15M, PVP K-30 terhadap pelepasan nifedipin, dan Avicel PH 102 terhadap floating lag time tablet floating nifedipin, serta untuk mengetahui proporsi masing-masing bahan untuk membuat formula optimum tablet floating nifedipin. Penelitian dilakukan dengan metode simplex lattice design (SLD) dengan 3 komponen yaitu HPMC K15M, PVP K-30 dan Avicel PH 102 sehingga diperoleh 14 formula. Parameter optimasi terdiri
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Sandeep, A. Wathore *. Vijaykumar M. Kale Yuvraj L. Pandhare. "FORMULATION AND EVALUATION OF FLOATING TABLETS OF CEFUROXIME AXETIL." Journal of Pharma Research 8, no. 8 (2019): 544–49. https://doi.org/10.5281/zenodo.3374079.

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<strong><em>ABSTRACT</em></strong> <strong><em>T</em></strong><em>he objective of research work was to formulate and evaluate the floating drug delivery system containing cefuroxime axetil using polymer HPMC K4M, Guar Gum.&nbsp; Effervescent floating tablets containing Cefuroxime axetil were prepared by direct compression technique using varying concentrations of different grades of polymer. Physical parameters like hardness, weight variation, thickness and friability were within pharmacopoeial limit. Percentage drug content in all floating tablet formulations was found to be 90% to 110%. The
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Patel, Keyur S., Akshar N. Rao, Deepa R. Patel, Dhaval M. Patel, and Advaita B. Patel. "Formulation and Evaluation of Gastroretentive Floating Tablets of Quetiapine Fumarate." Journal of Drug Delivery and Therapeutics 11, no. 3-S (2021): 65–73. http://dx.doi.org/10.22270/jddt.v11i3-s.4833.

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The objective of the present study was to develop gastroretentive floating tablets of quetiapine fumarate. The gastroretentive floating tablets of quetiapine fumarate were formulated using natrosol 250 HHX as a sustained release polymer and sodium bicarbonate as a gas forming agents. A 32 factorial design was employed to study the influence of concentration of natrosol HHX 250 (X1) and concentration of sodium bicarbonate (X2) on the dependent variables % drug release at 1h (Y1), % drug release at 8 h (Y2) and floating lag time (Y3). The optimized formulation (O1) showed floating lag time 49 ±
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Patel, Upasana J., Hitesh kumar A. Patel, Bhumika J. Limbachiya, and Mehzabeen Jhankhwala. "Formulation, development and optimization of gastroretentive floating pellets of febuxostat." Journal of medical pharmaceutical and allied sciences 11, no. 1 (2022): 4317–23. http://dx.doi.org/10.55522/jmpas.v11i1.2095.

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The aim of the study was to develop gastro retentive floating pellets of febuxostat used to treat gout condition which having low solubility and high bioavailability. The gastro retentive floating pellets of febuxostat were formulated using Gelucire 43/01 and ethyl cellulose as a sustain release polymer and microcrystalline cellulose as spheronizing agent by extrusion- spheronization technique. A 32 full factorial design was applied to investigate the effect of the two-independent variable, that is, ratio of Drug: Gelucire (X1) and ratio of Drug: ethyl cellulose (X2), on the dependent variable
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Tania, Alinda, Fitrya Fitrya, and Najma Fithri. "FORMULASI DAN EVALUASI TABLET SISTEM GASTRORETENTIF EKSTRAK DAUN PETAI (Parkia speciosa Hassk.) MENGGUNAKAN HPMC-K4M DAN CARBOPOL® 934P." ISTA Online Technologi Journal 4, no. 2 (2023): 01–17. http://dx.doi.org/10.62702/ion.v4i2.85.

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Tukak peptik adalah luka yang dapat terjadi pada lambung dan usus halus bagian atas dengan prevalensi 6 – 15% terutama pada usia 20 – 50 tahun. Obat-obatan sintetis masih menjadi pilihan utama dalam pengobatan, namun ada banyak tanaman yang diketahui berkhasiat sebagai obat antitukak. Salah satu tanaman yang berkhasiat sebagai antitukak adalah petai (Parkia speciosa). Daun petai dapat diformulasi menjadi tablet floating-mucoadhesive dengan polimer HPMC-K4M dan Carbopol®934P, sehingga pelepasan obat tertarget di saluran pencernaan atas. Penelitian ini bertujuan untuk mengetahui pengaruh komposi
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Gaur, A., and H. P. Shah. "Formulation, Development and Evaluation of floating tablet of Metformin Hydrochloride using optimization of gas generating agent." Formulation, Development and Evaluation of floating tablet of Metformin Hydrochloride using optimization of gas generating agent 1, no. 3 (2011): 26–31. https://doi.org/10.5281/zenodo.12699386.

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The present study deals with drug release enhancement of MetforminHydrochloride using floating technology by optimization of gas generating agent to improvethe buoyancy time. Metformin hydrochloride is a oral antihyperglycemic agent of biguanideclass used in treatment of type 2 Diabetes. It is hydrophilic drug which absorbed slowly andnot completely form the gastrointestinal tract. The absolute bioavailability is reported to be50-60%. This technology uses direct compression method to prepare floating tablet ofMetformin Hydrochloride with release retardant polymer HPMC K-100, PVP K-30, Carbopol
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K R, Shankar, Aminabee S, Ramana G, Lakshmi KNVC, and Indusree G. "Formulation and Evaluation of Propranolol Hydrochloride Floating Tablets by 32 Factorial Design." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 04 (2024): 1716–21. https://doi.org/10.25258/ijddt.14.4.17.

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The goal of current work is to develop Propranolol HCl floating tablets. Floating tablets of Propranolol HCl were designed basing on the idea of gas generation. Using sodium bicarbonate (NaHCO3) as a gas-generating agent, xanthan gum, polyox WSR 303a as a matrix-forming polymer, and HPMC K4 M and K15 M as matrix-forming polymers, matrix tablets totalling 40 mg of propranolol HCl were created.Among the four polymers namely HPMCK4M, HPMCK15M, Xanthan gum and Polyox WSR, HPMC K4M gave good release and was selected for formulation of propranolol HCl floating tablets by 32 factorial design. Propran
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Tripathi, Ankita, Suraj Neupane, Khushboo Bhardwaj, Shiva Mishra, Meenakshi Gupta, and Raj Kumar Mishra. "FLOATING DRUG DELIVERY SYSTEM OF NSAIDS TO INCREASE GASTRIC RETENTION TIME IN UPPER PART OF GASTROINTESTINAL TRACT." International Research Journal of Pharmacy 12, no. 1 (2021): 33–39. http://dx.doi.org/10.7897/2230-8407.1201115.

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The purpose of the present work is to prolong the gastric residence time of Lornoxicam by developing gastric floating drug delivery system. Lornoxicam is non-steroidal anti-inflammatory drugs. Its short half life 2 to 3 hrs and maximal absorption of upper part of gastrointestinal tract. The residence time of the dosage form in the stomach depends upon various factors like pH, size of the dosage form, food intake, and biological factors which include age, body weight gender, posture, and diseased states Floating tablet prepared by melt granulation techniques, using bees wax as a binder and the
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Dissertations / Theses on the topic "Floating lag time"

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Thitinan, Sumalee. "Development of multiple dose platforms for oral drug delivery." Thesis, 2011. http://hdl.handle.net/2152/ETD-UT-2011-12-4529.

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Multiple dose regimens are frequently required to optimize therapy; however, such therapy is frequently undermined by poor patient adherence. In fact, patient adherence is inversely related to the number of doses a patient is asked to take each drug. Consequently, great efforts are under way to develop drug delivery systems that are able to release drugs over an extended time interval; this could offer considerable benefits including reducing administration frequency. This dissertation describes multiple dose platforms designed to deliver a variety of drugs as a single oral administration a
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Book chapters on the topic "Floating lag time"

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Srikar, Grandhi, and I. Nagamma. "Quality by Design Approach for Optimization and Development of Gastro-Retentive Hollow Microspheres for Prasugrel." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00414.

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Prasugrel (PSG) is used in minimizing the risk of atherothrombotic events in people with cardiovascular problems. Developing extended-release products for PSG is highly advantageous owing to its pharmacodynamic and pharmacokinetic properties. But, due to its insolubility in aqueous media with pH above 6.0, it becomes poorly bioavailable from the small intestine upon oral administration. Hence, an extended-release formulation which resides in gastric region until released completely is highly recommended. Polymeric hollow-microspheres with inherent floating property without lag time are highly
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Cally, Jordan. "Part IV Market Institutions And International Capital Markets, 12 Intermediaries—From Handmaiden to New Market." In International Capital Markets, edited by Golden Jeffrey. Oxford University Press, 2021. http://dx.doi.org/10.1093/law/9780198849001.003.0012.

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This chapter studies the roles of intermediaries. As exchanges developed in Western Europe and the colonies, they spun out a widening web of intermediaries participating in the process of trading financial products. In the lead up to the global financial crisis, the roles assumed by intermediaries, and their sources of revenue, had mutated over time. Intermediaries became issuers and capital raisers in their own right. Originally handmaidens to the exchanges, intermediaries created a new, free floating, trading world. In this new trading world, the potential conflicts of interest inherent in a
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Verhagen, Hendrik L. E. "From Special to General Pledge." In Security and Credit in Roman Law. Oxford University PressOxford, 2022. http://dx.doi.org/10.1093/oso/9780199695836.003.0010.

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Abstract In the second half of the second century ad a pledge originated which extended to all the assets which were from time to time part of the debtor’s patrimony. For centuries the general pledge has given rise to two questions: what was its object and what were its legal consequences? This chapter will first look at generic pledges as ancestors of the general pledge. The origin of the general pledge, via the intermediate stage of the so-called cetera bona pledge, will then be charted. The remaining sections of this chapter will review the legal consequences of the general pledge. It will
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Olivelle, Patrick. "Authorship And Composition." In Manu’s Code Of Law. Oxford University PressNew York, NY, 2004. http://dx.doi.org/10.1093/oso/9780195171464.003.0001.

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Abstract Scholars traditionally have regarded the composition of the MDh as a gradual process at the hands of anonymous and successive compilers, editors, and copyists lasting for several centuries, the same sort of agentless process that many have thought lies behind the composition of the great epic Mahiibhiirata. These compilers and editors, we are told, did nothing more than gather together proverbial sayings, moral maxims, and legal axioms that were floating in the mouths of people and handed down from generation to generation. The composition of the text is thus divorced from authorial i
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French, Derek. "11. Borrowing and security." In Mayson, French, and Ryan on Company Law. Oxford University Press, 2023. http://dx.doi.org/10.1093/he/9780198874317.003.0011.

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This chapter considers borrowing as an important method of financing a company’s activities, and security as a right of recourse against company property if the loan is not repaid on time. It begins by discussing security for financial obligations, paying particular attention to security contracts, the redemption or discharge of security and the realisation of security. It then turns to the registration of non-possessory security contracts, the priorities of legal and equitable charges and floating charges as a form of security and their crystallisation. The extent to which the assets of a com
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French, Derek. "11. Borrowing and security." In Mayson, French & Ryan on Company Law. Oxford University Press, 2019. http://dx.doi.org/10.1093/he/9780198841517.003.0011.

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This chapter considers borrowing as an important method of financing a company’s activities, and security as a right of recourse against company property if the loan is not repaid on time. It begins by discussing security for financial obligations, paying particular attention to security contracts, the redemption or discharge of security and the realisation of security. It then turns to the registration of non-possessory security contracts, the priorities of legal and equitable charges and floating charges as a form of security and their crystallisation. The extent to which the assets of a com
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French, Derek. "11. Borrowing and security." In Mayson, French & Ryan on Company Law. Oxford University Press, 2017. http://dx.doi.org/10.1093/he/9780198797234.003.0011.

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This chapter considers borrowing as an important method of financing a company’s activities, and security as a right of recourse against company property if the loan is not repaid on time. It begins by discussing security for financial obligations, paying particular attention to security contracts, the redemption or discharge of security and the realisation of security. It then turns to the registration of non-possessory security contracts, the priorities of legal and equitable charges and floating charges as a form of security and their crystallisation. The extent to which the assets of a com
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French, Derek. "11. Borrowing and security." In Mayson, French & Ryan on Company Law. Oxford University Press, 2021. http://dx.doi.org/10.1093/he/9780198870029.003.0011.

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This chapter considers borrowing as an important method of financing a company’s activities, and security as a right of recourse against company property if the loan is not repaid on time. It begins by discussing security for financial obligations, paying particular attention to security contracts, the redemption or discharge of security and the realisation of security. It then turns to the registration of non-possessory security contracts, the priorities of legal and equitable charges and floating charges as a form of security and their crystallisation. The extent to which the assets of a com
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Bogataj, David, and Damjana Drobne. "Control of Perishable Goods in Cold Logistic Chains by Bionanosensors." In Materials Science and Engineering. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-1798-6.ch019.

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Nanotechnology can contribute to food security in supply chains of agri production-consumption systems. The unique properties of nanoparticles have stimulated the increasing interest in their application as biosensing. Biosensing devices are designed for the biological recognition of events and signal transduction. Many types of nanoparticles can be used as biosensors, but gold nanoparticles have sparked most interest. In the work presented here, we will address the problem of fruit and vegetable decay and rotting during transportation and storage, which could be easily generalized also onto p
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Conference papers on the topic "Floating lag time"

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Mahajanam, Sudhakar, Jane Brown, Krista Heidersbach, and Lokesh Choudhary. "Aluminum Floating Roof Damage from Hydrotesting." In CONFERENCE 2024. AMPP, 2024. https://doi.org/10.5006/c2024-20804.

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Abstract During construction or refurbishment of crude oil tanks, hydrotesting is routinely performed, sometimes with an aluminum floating roof or pontoons in place. Upon occasion, damage has been sustained to the aluminum floating roofs in a relatively short period of time. Damage is commonly believed to be a result of poor water quality with bacteria or chlorides being suspected of causing the corrosion. Galvanic coupling between the roof and the carbon steel tank has also been cited as a potential contributing factor. Experiments were set up using three types of aluminum alloys: AA 3003, AA
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Dockens, Kim, Shawna Johnston, Marc Demeter, and Stan Leong. "Comparison of Planktonic and Sessile Bacteria Counts Using ATP and DNA Based Methods." In CORROSION 2017. NACE International, 2017. https://doi.org/10.5006/c2017-09414.

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Abstract Microbiologically influenced corrosion (MIC) is a term used to describe corrosive damage to metals caused by microbes. Corrosion damage is costly to operations, the environment and life. As such, monitoring for, and diagnosing MIC as part of a complete corrosion mitigation strategy is of paramount importance. Traditional MIC diagnostic techniques employ culture-based methods aimed at enumerating microbes presumed to be associated with MIC. Culture-based diagnostics are time consuming and may severely under estimate populations. Moreover, microbes mediating corrosion typically exhibit
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O’Sullivan, Keith, Jimmy Murphy, and Dara O’Sullivan. "Power Output Performance and Smoothing Ability of an Oscillating Water Column Array Wave Energy Converter." In ASME 2013 32nd International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/omae2013-11375.

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This paper presents the physical model testing results of a floating oscillating water column (OWC) array wave energy converter (WEC) and the power smoothing ability inherent in the OWC chamber arrangement in the structure. The device can be categorised as a very large floating structure (VLFS) with structure dynamics which may make it a suitable device on which to mount wind turbines. It incorporates 32 individual OWC chambers in a “V” shaped arrangement such that there is a phase-lag between successive wave crests in the OWC chambers as an individual wave passes the structure. This OWC array
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Gang, Chen, Zhao Nan, Zhang Wei, Yuan Hongtao, Li Chunhui, and Yang Yong. "Hydrodynamic Performance Effect of Steel Catenary Risers on Wave Frequency Motions of a Semi Submersible." In ASME 2016 35th International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/omae2016-54092.

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The analysis of the influence of risers on the motions of a floating platform is often conducted and simplified by uncoupled method. As the number of risers and water depth increase, this method would not predict system motion accurately. Coupled analysis method in time domain becomes a very convenient approach in response calculation since it automatically includes the interaction among platform, mooring lines and risers. This paper introduces a full coupled approach by AQWA-NAUT to include viscous damping of the semi submersible and effects of steel catenary risers on the wave frequency resp
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Mathisen, Jan, and Torfinn Hørte. "A Probabilistic Metocean Model for Mooring Response in Gulf of Mexico Hurricanes." In ASME 2013 32nd International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/omae2013-10735.

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Hindcast data for a specific location is utilised to develop a joint probability function for the metocean variables that are expected to have a significant effect on mooring line tensions for a floating platform moored at that location. The main random variables comprise: peak significant wave height, peak wind speed, peak surface current speed, peak wave direction, peak wind direction and peak current direction, where “peak” indicates the maximum intensity of the metocean effect during a random hurricane. The time lead of peak wind relative to peak waves and the time lag of peak current afte
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Milano, Daniel, Christophe Peyrard, Matteo Capaldo, David Ingram, Qing Xiao, and Lars Johanning. "Impact of High Order Wave Loads on a 10 MW Tension-Leg Platform Floating Wind Turbine at Different Tendon Inclination Angles." In ASME 2019 38th International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/omae2019-96243.

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Abstract Floating wind technology is being developed rapidly with the aim of harvesting high-energy wind resources in medium and deep water areas, unreachable using fixed bottom solutions. Given the complexity of these systems, the interactions between the structure and incident hydro-aerodynamic forces need to be well understood. While numerous solutions are being explored, an optimal design is yet to be established within the industry. This study explores the effects of tendon inclination on the dynamic behaviour of a 10MW tension-leg platform (TLP) floating offshore wind turbine (FOWT), and
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Jensen, Jo̸rgen Juncher. "Extreme Load Predictions for Floating Offshore Wind Turbines." In ASME 2009 28th International Conference on Ocean, Offshore and Arctic Engineering. ASMEDC, 2009. http://dx.doi.org/10.1115/omae2009-79160.

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An effective stochastic procedure for extreme value predictions related to wave and wind induced stochastic loads is applied to a tension-leg concept for floating offshore wind turbines. The method is based on the First Order Reliability Method (FORM) and as the procedure makes use of only short time-domain simulations all kinds of non-linearities can be included. The procedure has been used previously for wave induced loads and is in this note extended to combined wave and wind loads.
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Martin, Heather R., Richard W. Kimball, Anthony M. Viselli, and Andrew J. Goupee. "Methodology for Wind/Wave Basin Testing of Floating Offshore Wind Turbines." In ASME 2012 31st International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/omae2012-83627.

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Scale model wave basin testing is often employed in the development and validation of large scale offshore vessels and structures by the oil and gas, military and marine industries. A basin model test requires less time, resources and risk than a full scale test while providing real and accurate data for model validation. As the development of floating wind turbine technology progresses in order to capture the vast deepwater wind energy resource, it is clear that model testing will be essential for the economical and efficient advancement of this technology. However, the scale model testing of
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Xu, Yuwang, Ole Øiseth, and Torgeir Moan. "Time Domain Modelling of Frequency Dependent Wind and Wave Forces on a Three-Span Suspension Bridge With Two Floating Pylons Using State Space Models." In ASME 2017 36th International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/omae2017-62721.

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Floating suspension bridges, one of several new designs to make it possible to cross deep and wide fjords, consist of three spans and supported by two tension leg platforms and two fixed traditional concrete pylons. Geometric nonlinearities, nonlinear aerodynamic and hydrodynamic forces and nonlinear mooring systems can become of high importance. Time domain methods are commonly applied when nonlinearities need to be considered. The main challenge in time domain simulation of the floating suspension bridge is the modelling of frequency-dependent aerodynamic self-excited forces and hydrodynamic
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Naess, A., O. Gaidai, and P. S. Teigen. "Simulation Based Estimation of Extreme Response of Floating Offshore Structures." In ASME 2007 26th International Conference on Offshore Mechanics and Arctic Engineering. ASMEDC, 2007. http://dx.doi.org/10.1115/omae2007-29079.

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The paper presents a study of the extreme response statistics of a tension leg platform (TLP) subjected to random seas. Two different approaches are compared: A numerical integration method based on saddle point integration and the Monte Carlo method. While the saddle point method is a mathematically attractive technique, which gives numerically very accurate results at low computational costs at any response level, the advantage of the Monte Carlo method is its simplicity and versatility. It is demonstrated in this paper that the commonly assumed obstacle against using the Monte Carlo method
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