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Relevant bibliographies by topics / Floating microballoons

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Journal articles

Academic literature on the topic 'Floating microballoons'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Floating microballoons"

1

Srivastava, Ankita, Ruchi Shukla, Kusum Sharma, Hitesh Jain, and D. B. Meshram. "Microballoons: A Gastro Retentive Drug Delivery System." Journal of Drug Delivery and Therapeutics 9, no. 4-s (2019): 625–30. http://dx.doi.org/10.22270/jddt.v9i4-s.3274.

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Oral route is most preferable and widely used route for the administration of drug. Microballoons becomes novel technology in pharmaceutical field in the floating drug delivery for achieving the gastric retention. Microballoons are also called as hollowspheres which are porous smooth in nature and thus show good floating properties in gastric fluid. Microballoons release the drug in controlled manner at the targeted site. Microballoons are spherical empty vesicles without core and that can remain buoyant in gastric region for prolong period of time without irritation in gastrointestinal tract.

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2

Manivannan, Subramanian, Akshay M, Bhuvaneswari S, and Nify F. "FORMULATION AND EVALUATION OF GASTRORETENTIVE MICROBALLOONS OF ACEBROPHYLLINE FOR THE TREATMENT OF BRONCHIAL ASTHMA." Asian Journal of Pharmaceutical and Clinical Research 9, no. 5 (2016): 105. http://dx.doi.org/10.22159/ajpcr.2016.v9i5.12603.

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ABSTRACTObjective: Gastroretentive dosage forms are an approach for prolonged and predictable drug delivery in the upper gastrointestinal tract to controlthe gastric residence time. Microballoons are considered as one of the most promising buoyant drug delivery systems as they possess the advantagesof both multiple-unit systems and good floating properties. Acebrophylline is a xanthine derivative with potent bronchodilator, mucosecretolytic, andanti-inflammatory property. It is used to treat bronchial asthma and chronic obstructive pulmonary diseases.Methods: Microballoons of acebrophylline we

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3

R. Lankapalli, Sasidhar, Vidyadhara Suryadevara, Sowjanya L. Battula, and Ramu Anne. "DEVELOPMENT AND EVALUATION OF CAPTOPRIL CONTROLLED RELEASE FLOATING MICROBALLOONS." Indian Drugs 59, no. 08 (2022): 31–38. http://dx.doi.org/10.53879/id.59.08.11130.

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The objective of the present study was to develop floating microballoons of captopril in order to achieve an extended gastric retention in the upper GIT which may enhance the absorption and improve bioavailability. The floating microballoons were formulated with calcium silicate as porous carrier, Eudragit L100 and ethyl cellulose 7 cps as coating polymers and captopril as model drug. The prepared microballoons were evaluated for particle size, angle of repose, Carr’s index, buoyancy studies, drug content and for in vitro drug release. Based upon the dissolution data obtained and various physi

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4

Gurpreet, Kaur* Ashita Pawaiya Damandeep Kaur Rajat Kumar Sharma. "Microballoons- Novel Approach in Floating Drug Delivery System." International Journal of Pharmaceutical Sciences 2, no. 12 (2024): 2293–309. https://doi.org/10.5281/zenodo.14501085.

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Recent developments in floating delivery systems for pharmaceuticals (FDDS), which included the uniform dispersion of multiparticulate dose forms along the GIT, led to the development of gastro-retentive floating microspheres. This may result in less chance of local discomfort and more reliable drug absorption. As a dose form with remarkable buoyancy in the stomach, microballoons (MB), a multi-unit prolonged release with a sphere-shaped hollow wrapped in a strong polymer shell, have been developed. Because stomach acid has a lower relative density than this preparation for limited intestinal a

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5

Malik, Prashant, Upendra Nagaich, Raj Kaur Malik, and Neha Gulati. "Pentoxifylline Loaded Floating Microballoons: Design, Development and Characterization." Journal of Pharmaceutics 2013 (May 9, 2013): 1–5. http://dx.doi.org/10.1155/2013/107291.

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The floating microballoons have been utilized to obtain prolonged and uniform release in the stomach. The objective of the present study involves design, development, and characterization of pentoxifylline loaded floating microballoons to prolong their gastric residence time. Pentoxifylline (trisubstituted xanthine derivative) loaded microballoons were prepared by the solvent evaporation technique using different concentrations of polymers like HPMC K4M and ethyl cellulose (EC) in ethyl alcohol and dichloromethane organic solvent system. Microballoons were characterized for their particle size

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6

Negia, Rakhi, Laxmi Goswamia, and Preeti Kothiyal. "Microballoons: A better approach for gastro retention." Indian Journal of Pharmaceutical and Biological Research 2, no. 02 (2014): 100–107. http://dx.doi.org/10.30750/ijpbr.2.2.17.

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The purpose of this review is to accumulate the recent study on floating drug delivery system with special emphasis on microballoons as drug delivery. Microballoons are emerging as the most promising drug delivery as it overcome many limitations of conventional drug delivery system. As microballoons delivery system provides longer retention in gastric pH, hence longer is the residence time and therefore enhance the solubility of drugs that are less soluble in high pH environment. The formation of cavity inside the microsphere depends upon the preparation temperature and the surface smoothness

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7

S., Supriya, and M. Swetha* Dr. "A REVIEW ON MICROBALLOONS." World Journal of Pharmaceutical Science and Research 2, no. 4 (2023): 21–24. https://doi.org/10.5281/zenodo.10897607.

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Microballoons also known as hollow sphere drug delivery systems. These are typically spherical in size from 200 microns and do not have a core. They have a gastric retention drug delivery system (GRDDS), which can improve drug bioavailability and reduce stomach irritation. These floating microballoons have the convenience that they stay buoyant and circulate uniformly over the gastric ingredients to withhold the variations of gastric emptying and release the drug for extended period of time. It’s floating containing synthetic polymers that improves the processing of solid dosage forms su

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8

Penjuri, S. C. B., R. Nagaraju, S. Shaik, S. Damineni, and S. R. Poreddy. "GASTRORETENTIVE MICROBALLOONS OF RIBOFLAVIN: FORMULATION AND EVALUATION." INDIAN DRUGS 54, no. 04 (2017): 47–52. http://dx.doi.org/10.53879/id.54.04.10708.

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Gastroretentive dosage forms are useful to extend release of drugs having a narrow window of absorption in the upper intestine and for drugs degraded by higher pH or for drugs with local action in the proximal part of the GI tract. In the present study, an attempt was made to prepare microballoons of riboflavin by emulsion solvent diffusion method by using HPMC and ethylcellulose in order to extend the drug release in the upper GIT, which may result in enhanced absorption and thereby improved bioavailability. The size and surface morphology of riboflavin microballoons were characterized by opt

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9

Pandey, Chandra Prakash, and ,. Archana. "Development and Evaluation of Gastro Retentive Mucoadhesive Microballoons of Esomeprazole to Treat Peptic Ulcer." Journal of Drug Delivery and Therapeutics 12, no. 4-S (2022): 128–39. http://dx.doi.org/10.22270/jddt.v12i4-s.5552.

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The Gastro-retentive medication delivery method may increase patient compliance by lowering drug plasma level fluctuations1. The absorption maxima (max) of esomeprazole magnesium in 0.1 N HCl solution were found to be at 291 nm. Correlation coefficient values better than 0.99 suggest that the calibration curves provide strong linearity data. The results showed that the medication was soluble in 0.1 N HCl and had the maximum solubility in water. Magnesium esomeprazole was found to have a partition coefficient of (0.2442). The prepared mucoadhesive microballons percentage yield was calculated, w

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10

Hajare, Pranit P., and Punit R. Rachh. "FORMULATION AND DEVELOPMENT OF NOVEL GASTRORETENTIVE MICROBALLOONS OF REPAGLINIDE." Journal of Advanced Scientific Research 12, no. 04 Suppl 1 (2021): 193–204. http://dx.doi.org/10.55218/jasr.s1202112421.

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The present study involves preparation and evaluation of Microballoons of Repaglinide which is having poor solubility in water and low oral bioavailability. Repaglinide, an oral hypoglycemic agent, is rapidly absorbed and eliminated from the body after oral administration. The peak plasma level occurs within an hour of oral administration with elimination half life of 1 hr. The objective of the present work is to prepare floating microballoons of Repaglinide for delivering the drug in controlled manner which will help to reduce dosing frequency and maintain the plasma concentration of drug for

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