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Dissertations / Theses on the topic 'Flow cell'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Rabodzey, Aleksandr. "Flow-induced mechanotransduction in cell-cell junctions of endothelial cells." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/41586.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Biological Engineering Division, 2006.<br>Includes bibliographical references (leaves 86-92).<br>Endothelial cells show an unexpected behavior shortly after the onset of laminar flow: their crawling speed decreases ~40% within the first 30 min, but only in a confluent monolayer of endothelial cells, not in subconfluent cultures, where cell-cell interactions are limited. This led us to study early shear effects on cell-cell adherens junctions. We found a 30±6% increase in the number of VE-cadherin molecules in the junctions. The strength o

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2

LASAGNA, DAVIDE. "Flow physics and control of trapped vortex cell flows." Doctoral thesis, Politecnico di Torino, 2013. http://hdl.handle.net/11583/2518621.

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The main objective of this work is to investigate on the physics and on the control of the flow in a Trapped Vortex Cell, often referred to as TVC in the following. A TVC is a cavity with a particular geometry, which is optimised to trap a vortical structure. This configuration has recently gained interest has a device to control the flow past thick airfoils, but fundamental research is still required to make this technique effective. Specifically, a first goal of this work is to investigate on the fundamental physics of this flow, by studying the basic elements and the dominant phenomena. I

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3

Kucukal, Erdem. "BIOMIMETIC MICROFLUIDIC PLATFORMS FOR MONITORING CELLULAR INTERACTIONS IN MICROSCALE FLOW." Case Western Reserve University School of Graduate Studies / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1576231265150031.

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4

Ofsthun, Norma Jean. "Cross-flow membrane filtration of cell suspensions." Thesis, Massachusetts Institute of Technology, 1989. http://hdl.handle.net/1721.1/14481.

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5

Han, Tian. "Flow cell separation in fluctuating g-field." Thesis, Brunel University, 2015. http://bura.brunel.ac.uk/handle/2438/11105.

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Field flow fractionation of particles in rotating coiled column has been investigated in recent year. In contrast to the classical mode of field flow fractionation in narrow channels, the use of rotating coiled columns offers the possibility of large sample loading. In this thesis, the potential for new cell separation methods based on the use of flow fractionation in fluctuating g-fields generated in rotating coil columns is examined. The effects of operational conditions (flow rate and rotational speed – Chapter 3 and Chapter 5); cell properties (cell flexibility – Chapter 4); and column sha

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6

Choe, Juno. "Genomic analysis by single cell flow sorting /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/10850.

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7

Dive, C. "Flow cytoenzymology with special reference to cancer chemotherapy." Thesis, Open University, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384585.

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8

Camplejohn, Richard Stephen. "Cell kinetics and cancer." Thesis, University of Newcastle Upon Tyne, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327272.

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9

Korn, Christian. "Stochastic dynamics of cell adhesion in hydrodynamic flow." Phd thesis, Universität Potsdam, 2007. http://opus.kobv.de/ubp/volltexte/2007/1299/.

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10

Allen, R. J. "Modelling the endothelial cell response to fluid flow." Thesis, University College London (University of London), 2009. http://discovery.ucl.ac.uk/16119/.

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In vitro endothelial cells respond to fluid flow by elongating in the direction of flow. How the mechanical signal is transformed into an organised and directed response is poorly understood. The most studied and crucial aspects to this response are; actin filament alignment, mechano-transduction, signal transduction, Rho GTPase localised activation and lamellipodium formation. The goal of this project is to understand how these separate facets interact and lead to a coordinated response. The flow is modelled over a 3D virtual cell, which naturally gives the force the flow exerts on the cell s

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11

Polacheck, William J. (William Joseph). "Effects of interstitial flow on tumor cell migration." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/61917.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2010.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 80-84).<br>Interstitial flow is the convective transport of fluid through tissue extracellular matrix. This creeping fluid flow has been shown to affect the morphology and migration of cells such as fibroblasts, cancer cells, endothelial cells, and mesenchymal stem cells. However, due to limitations in experimental procedures and apparatuses, the mechanism by which cells detect flow and the details and dynamics of the c

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12

Bose, Suman. "Affinity Flow Fractionation for label-free cell sorting." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/87961.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2014.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages [107]-118).<br>Capture and isolation of flowing cells from body fluids such as peripheral blood, bone marrow or pleural effusion has enormous implications in diagnosis, disease monitoring, and drug testing. However, in many situations the conventional methods of cell sorting are of limited use due to complex sample preparation steps, high costs, or low sensitivity. Drawing inspiration from nature, a novel platf

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13

Kimpton, Laura Saranne. "On two-phase flow models for cell motility." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:93c3cc12-4aac-424d-83bf-3e695efb49fe.

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The ability of cells to move through their environment and spread on surfaces is fundamental to a host of biological processes; including wound healing, growth and immune surveillance. Controlling cell motion has wide-ranging potential for medical applications; including prevention of cancer metastasis and improved colonisation of clinical implants. The relevance of the topic coupled with the naturally arising interplay of biomechanical and biochemical mechanisms that control cell motility make it an exciting problem for mathematical modellers. Two-phase flow models have been widely used in th

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14

Brown, Jason Britton. "An experimental facility for the investigation of the flow in a circular-couette flow bioreactor." Thesis, Georgia Institute of Technology, 1998. http://hdl.handle.net/1853/18174.

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15

Lähdesmäki, Ilkka Johannes. "Flow injection methods for drug-receptor interaction studies, based on probing cell metabolism /." Thesis, Connect to this title online; UW restricted, 1999. http://hdl.handle.net/1773/8590.

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16

Silva, Michael Santos. "Flow cytometric of c-FLIPl-mediated regulation of cell cycle and cell population size." Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22487.

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Mestrado em Bioquímica - Bioquímica Clínica<br>c-FLIP é uma proteína conhecida pela sua capacidade de se ligar ao DISC, onde compete com a procaspase-8 pela interação com FADD. No entanto, existem evidências que a sua isoforma longa consegue regular também o ciclo celular e mecanismos de proliferação. Para além disso, a atividade de c-FLIPL pode ser controlada por fosforilação. Assim, o objetivo deste estudo é perceber como a fosforilação no resíduo de serina 227 nesta proteína afeta a proliferação e ciclo celular. Neste estudo, observamos que a sobre-expressão de c-FLIPL com uma mutação de se

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17

Shaffer, Christian Edward. "Flow system modeling with applications to fuel cell systems." Morgantown, W. Va. : [West Virginia University Libraries], 2005. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=4198.

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Thesis (M.S.)--West Virginia University, 2005.<br>Title from document title page. Document formatted into pages; contains xii, 111 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 100-102).

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18

Tamaresis, John S. "Mathematical modeling of arterial endothelial cell responsiveness to flow /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2004. http://uclibs.org/PID/11984.

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19

Raina, Rajeev. "Development of a cell-based stream flow routing model." Thesis, Texas A&M University, 2003. http://hdl.handle.net/1969.1/2219.

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This study presents the development of a cell-based routing model. The model developed is a two parameter hydrological routing model that uses a coarse resolution stream network to route runoff from each cell in the watershed to the outlet. The watershed is divided into a number of equal cells, which are approximated as cascade of linear reservoirs or tanks. Water is routed from a cell downstream, depending on the flow direction of the cell, using the cascade of tanks. The routing model consists of two phases, first is the overland flow routing, which is followed by the channel flow routing. I

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20

Hasson, Ali Thuriya A. Razzak. "A flow cell to study formation potential of pulps." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ29377.pdf.

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21

Yamamoto, Miharu. "Coupling of Arterial Wall Cell Dynamics and Blood Flow." Thesis, University of Canterbury. Centre for Bioengineering, 2011. http://hdl.handle.net/10092/6288.

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The objective of this research is to investigate both mathematically and numerically the effects of vascular geometry upon the cellular dynamics in the endothelium and its consequence in the localisation of atherosclerosis. It is widely accepted that the formation of atherosclerotic plaques preferentially occurs at specific locations in the vasculature, such as arterial branches and bends. It has also been observed that, at the sites of plaque formation, the physiological functions of the vascular endothelium are impaired due to a defect in the production mechanisms of or diminished activities

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22

Alexander, R. G. "Flow cytometry and cell sorting in plant genetic manipulations." Thesis, University of Nottingham, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356016.

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23

Sayer, Robert Michael. "Atir flow cell developments and studies in atmospheric chemistry." Thesis, University of York, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250623.

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24

Madden, Jacqueline. "Flow cytometric assessment of T cell activation in asthma." Thesis, University of Southampton, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.245048.

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25

Bremner, Sherry. "A granular flow model of an annular shear cell." Doctoral thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20304.

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Machinery such as an IsaMillTM used in communition to produce fine particle sizes that allow minerals to be extracted are best modelled using granular flows. A single rheological description that captures all the features of granular flows has not yet been realised, although considerable progress towards a complete theory has been made. Existing models of such horizontally stirred mills are empirical, tend to be extremely dependent on boundary conditions and do not allow for confident extrapolation beyond their window of design. As a first step to understanding the dynamics inside the IsaMill

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26

Reyes, Eduardo Alberto. "Flow chamber for studying cell attachment to opaque substrates." [Gainesville, Fla.] : University of Florida, 2004. http://purl.fcla.edu/fcla/etd/UFE0008971.

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27

Melane, Xolani. "Visualisation of electrolyte flow fields in an electrolysis cell." Diss., University of Pretoria, 2015. http://hdl.handle.net/2263/57492.

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The performance and efficiency of an electrochemical system with gas evolution can be related to the mass transfer effects which are influenced by the resulting two-phase flow. The aim of this investigation was to develop a better understanding in the effects of current density, anode height and inter-electrode spacing on the electrolyte flow patterns and to validate Computational Fluid Dynamic (CFD) model predictions of the electrolyte flow patterns. The CFD model was developed in a previous study and was applied to the experimental rig developed for this study, in which the electrolysis of c

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28

McIlvenna, David. "Raman activated cell sorting and counting in continuous flow." Thesis, University of Glasgow, 2015. http://theses.gla.ac.uk/6333/.

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Bacteria play a key role in the natural maintenance of our ecosystem and are also used extensively in agriculture, environmental engineering and in the manufacturing of food products and medicines. However, it is estimated that up to 99% of all micro- organisms are currently unculturable. As a result, it is likely that a vast range of potentially useful phenotypes remain unknown. Current techniques to investigate unculturable cells, such as metagenomics, lack the ability to link a specific piece of genetic information to an originating cell. As heterogeneity of phenotypes exists in populations

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29

Duqi, Enri. "Continuos Flow Single Cell Separation into Open Microwell Arrays." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amsdottorato.unibo.it/4778/1/duqi_enri_tesi.pdf.

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A novel design based on electric field-free open microwell arrays for the automated continuous-flow sorting of single or small clusters of cells is presented. The main feature of the proposed device is the parallel analysis of cell-cell and cell-particle interactions in each microwell of the array. High throughput sample recovery with a fast and separate transfer from the microsites to standard microtiter plates is also possible thanks to the flexible printed circuit board technology which permits to produce cost effective large area arrays featuring geometries compatible with laboratory equip

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30

Duqi, Enri. "Continuos Flow Single Cell Separation into Open Microwell Arrays." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amsdottorato.unibo.it/4778/.

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A novel design based on electric field-free open microwell arrays for the automated continuous-flow sorting of single or small clusters of cells is presented. The main feature of the proposed device is the parallel analysis of cell-cell and cell-particle interactions in each microwell of the array. High throughput sample recovery with a fast and separate transfer from the microsites to standard microtiter plates is also possible thanks to the flexible printed circuit board technology which permits to produce cost effective large area arrays featuring geometries compatible with laboratory equip

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31

Poles, Richard R. "Free-surface flow in a shallow laterally heated cavity." Thesis, City University London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363313.

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32

Pinto, Preston Albert. "Novel Bio-inspired Aquatic Flow Sensors." Thesis, Virginia Tech, 2012. http://hdl.handle.net/10919/33807.

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Inspired by the roles of hair cells in nature, this study aims to develop and characterize two new sets of novel flow sensors. One set of sensors developed and studied in this work are flow sensors fabricated using carbon nanomaterials. These sensors are made by embedding carbon nanotubes (CNT) and carbon nanohorns (CNH) into a polymeric substrate and then tested by flowing a conductive aqueous solution over the surface of the exposed CNT and CNH. In response, a flow-dependent voltage is generated. The surface coverage and the electrical relationship between the sensor and water is investi

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33

Zheng, Hong. "Efficient Algorithms for the Cell Based Single Destination System Optimal Dynamic Traffic Assignment Problem." Diss., The University of Arizona, 2009. http://hdl.handle.net/10150/195304.

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The cell transmission model (CTM) based single destination system optimal dynamic traffic assignment (SD-SO-DTA) model has been widely applied to situations such as mass evacuations on a transportation network. Although formulated as a linear programming (LP) model, embedded multi-period cell network representation yields an extremely large model for real-size networks. As a result, most of these models are not solvable using existing LP solvers. Solutions obtained by LP also involve holding vehicles at certain locations, violating CTM flow dynamics. This doctoral research is aimed at developi

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34

Trotter, Martin James. "Intermittent blood flow in the murine SCCVII squamous cell carcinoma." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/31344.

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Intermittent blood flow in tumour microvasculature is believed to contribute to heterogeneity in tumour oxygen delivery; transient vessel nonperfusion is thought to result in acutely hypoxic cells resistant to conventional radiotherapy. This thesis describes three main areas of work: (1) the development of a histologic method capable of detecting intermittent blood flow in experimental tumours at the single vessel level; (2) the quantification and characterization of tumour blood flow fluctuations in the murine SCCVII carcinoma; and (3) the modification of tumour blood flow and the reduction o

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35

Chu, Chun-sing, and 朱振聲. "Flow cytometric analysis of cell-cycle regulatory proteins during apoptosis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31240070.

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36

Chu, Chun-sing. "Flow cytometric analysis of cell-cycle regulatory proteins during apoptosis /." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21490144.

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37

Martin, Ashley Diane. "Modulation of endothelial cell characteristics by pericytes." Thesis, University of Ulster, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287133.

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38

Piri, Hossein. "Flow visualization in 3D printed PEM fuel cell bipolar plates." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/62259.

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In recent years, due to the public concern on global warming, both increasing energy efficiency and developing green energy become crucially important. Fuel cells can be one of the most suitable clean energy solutions for the environment because of its high energy conversion efficiency and near zero emissions of criteria air pollutants at the use stage. To increase the energy efficiency of fuel cells, effectively utilize the Pt catalyst and increase the fuel cell durability, the uniform distribution of the reactants over the fuel cell active area is of great importance. Over the last decade, m

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39

Godoy, Ramirez Karina. "Flow cytometric methods for assessment of cell-mediated immune responses /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-409-0/.

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40

O'Connell, Gregory Raymond. "Detector cell hydrodynamics and electrode selectivity in flow-injection potentiometry." Thesis, Brunel University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.290935.

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41

Bae, C. H. "Cell design and electrolytes of a Novel Redox flow battery." Thesis, University of Manchester, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509374.

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42

Bessaih, Nabil. "Erosion of sediment from a cell under high velocity flow." Thesis, University of Salford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386404.

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43

Medina, Jose L. "Work-cell Centric Satellite Pulse Flow Production System Integration Test." Digital Commons at Loyola Marymount University and Loyola Law School, 2012. https://digitalcommons.lmu.edu/etd/419.

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44

Moshaei, Mohammad Hossein. "Adhesion of Rolling Cell to Deformable Substrates in Shear Flow." Ohio University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou153373230467728.

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45

Kim, Jungtae. "Development of continuos flow micro cell sorter using immune magnetophoresis." Aachen Shaker, 2008. http://d-nb.info/992481430/04.

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46

Karp-Boss, Lee. "Phytoplankton-flow interactions in relation to cell size and morphology /." Thesis, Connect to this title online; UW restricted, 1998. http://hdl.handle.net/1773/11004.

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47

Poon, Grace Chemical Sciences &amp Engineering Faculty of Engineering UNSW. "Bromine complexing agents for use in vanadium bromide (V/Br) redox flow cell." Publisher:University of New South Wales. Chemical Sciences & Engineering, 2008. http://handle.unsw.edu.au/1959.4/41210.

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The Vanadium bromide (V/Br) flow cell employs the Br3-/Br- couple in the positive and the V(II)/V(III) couple in the negative half cell. One major issue of this flow cell is bromine gas formation in the positive half cell during charging which results from the low solubility of bromine in aqueous solutions. Bromine complexing agents previously used in the zinc-bromine fuel cell were evaluated for their applicability in V/Br flow cell electrolytes. Three quaternary ammonium bromides: N-ethyl-N-methyl-morpholinium bromide (MEM), N-ethyl-N-methyl-pyrrolidinium bromide (MEP) and Tetra-butyl ammoni

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48

Pomalis, Richard. "A fundamental study of Starling flow and protein redistribution within a cell-free rectilinear membrane flow device." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq20982.pdf.

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49

Sawyer, Frederick Emile. "Coupled mixing-cell and mass balance flow path models of the White River Flow System, Nevada, USA." abstract and full text PDF (UNR users only), 2009. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1467765.

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50

FACCHINETTI, IRENE. "Thermally Regenerable Redox-Flow Batteries." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2021. http://hdl.handle.net/10281/308694.

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Il calore a bassa temperatura (LTH), inferiore a 100°C, è una forma di energia largamente disponibile che viene dispersa nell’ambiente, senza alcun utilizzo. La conversione di questo tipo di energia in elettricità aprirebbe le porte allo sfruttamento di fonti energetiche come il calore solare, geotermico e di scarto industriale. La conversione di LTH in elettricità non è però un processo efficiente a causa dei limiti posti dalla termodinamica, con la cosiddetta legge di Carnot, oltre che ai limiti tecnologici che riducono ulteriormente la conversione di questa forma di energia. I dispositivi

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