Academic literature on the topic 'Fluoroamines'

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Journal articles on the topic "Fluoroamines"

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Toulgui, Ch, M. M. Chaabouni та A. Baklouti. "Synthese de β-fluoroamines". Journal of Fluorine Chemistry 46, № 3 (1990): 385–91. http://dx.doi.org/10.1016/s0022-1139(00)82924-3.

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Médoc, M., and F. Sobrio. "Nucleophilic radiofluorination at room temperature via aziridinium intermediates." RSC Adv. 4, no. 67 (2014): 35371–74. http://dx.doi.org/10.1039/c4ra07158a.

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Posakony, Jeffrey J., and Timothy J. Tewson. "Fluoroamines via Chiral Cyclic Sulfamidates." Synthesis 2002, no. 06 (2002): 766–70. http://dx.doi.org/10.1055/s-2002-25766.

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Okoromoba, Otome E., Zhou Li, Nicole Robertson, et al. "Achieving regio- and stereo-control in the fluorination of aziridines under acidic conditions." Chemical Communications 52, no. 91 (2016): 13353–56. http://dx.doi.org/10.1039/c6cc07855a.

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DMPU–HF demonstrates good reactivity and regioselectivity in conversion of aziridines into biologically important β-fluoroamines. The stereochemistry of aziridine-opening was found to be depend greatly on substitution pattern.
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Chevis, Philip J., Sirilak Wangngae, Thanaphat Thaima та ін. "Highly diastereoselective synthesis of enantioenriched anti-α-allyl-β-fluoroamines". Chemical Communications 55, № 43 (2019): 6050–53. http://dx.doi.org/10.1039/c9cc02765c.

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A highly diastereoselective synthesis (dr = 99 : 1 97 : 3) of enantioenriched anti-α-allyl-β-fluoroamines (ee = 86–92%) has been developed involving a highly diastereoselective Petasis allyl borono-Mannich reaction of (S)- or (R)-α-fluoroaldehydes.
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Park, Hyeonjeong, Doo-Ha Yoon, Hyun-Joon Ha, Se In Son, and Won Koo Lee. "Asymmetric Synthesis of Fluoroamines from Chiral Aziridines." Bulletin of the Korean Chemical Society 35, no. 3 (2014): 699–700. http://dx.doi.org/10.5012/bkcs.2014.35.3.699.

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Posakony, Jeffrey J., and Timothy J. Tewson. "ChemInform Abstract: Fluoroamines via Chiral Cyclic Sulfamidates." ChemInform 33, no. 34 (2010): no. http://dx.doi.org/10.1002/chin.200234081.

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Hamman, S., та C. G. Beguin. "Selective reduction of β-fluoroazides to β-fluoroamines". Journal of Fluorine Chemistry 37, № 2 (1987): 191–96. http://dx.doi.org/10.1016/s0022-1139(00)82016-3.

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Posakony, J. J., and T. J. Tewson. "The synthesis and characterization of [18F]-labeled fluoroamines." Journal of Labelled Compounds and Radiopharmaceuticals 44, S1 (2001): S925—S926. http://dx.doi.org/10.1002/jlcr.25804401325.

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O’Reilly, Matthew C., та Craig W. Lindsley. "A general, enantioselective synthesis of β- and γ-fluoroamines". Tetrahedron Letters 54, № 28 (2013): 3627–29. http://dx.doi.org/10.1016/j.tetlet.2013.04.116.

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Dissertations / Theses on the topic "Fluoroamines"

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Corro, Morón Macarena. "Novel Strategies for the Syntheses of Sphingosine Kinase Inhibitors, b-Fluoroamines and Enantioenriched Allenes." Doctoral thesis, Universitat Rovira i Virgili, 2018. http://hdl.handle.net/10803/665123.

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Els esfingolípids tenen un paper molt important tant en processos biològics com fisiològics i es converteixen els uns en els altres per l'acció d'enzims. El futur cel·lular és determinat pel balanç que controla la síntesi de ceràmida, esfingosina i esfingosina-1-fosfat, esfingolípids associats al càncer. Mentres que la ceràmida com l'esfingosina estan associades a processos d'apoptosi cel·lular, l'esfingosina-1-fosfat està vinculada a la proliferació. Degut a això, molts grups d'investigació centren els seus treballs en la síntesi d'inhibidors d'esfingosina quinasa, enzim que promou la formaci
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Duthion, Béranger. "Réarrangement stéréospécifique de β-aminoalcools : synthèse de 1,2-aminoalcools et β-fluoroamines biologiquement actifs". Paris 6, 2011. http://www.theses.fr/2011PA066017.

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Anxionnat, Bruno. "Synthèse de beta-fluoroamines cycliques par réarrangement de beta-aminoalcools et réactions tandem via des transferts d'hydrogène catalysés par des complexes d'iridium." Paris 6, 2013. http://www.theses.fr/2013PA066817.

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Médoc, Marie. "Radiosynthèse et évaluation biologique de radiotraceurs pour la visualisation en TEP de l'apoptose et marquage au fluor-18 de β-fluoroamines via un intermédiaire aziridinium". Caen, 2014. http://www.theses.fr/2014CAEN3151.

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La tomographie par émission de positons (TEP) est une technique d’imagerie médicale nécessitant l’utilisation de radiopharmaceutiques et permettant la visualisation au niveau moléculaire de nombreux phénomènes biologiques in vivo. L’apoptose est une forme de mort cellulaire programmée intervenant dans de nombreuses pathologies (ischémies, cancers, maladies autoimmunes…). De nombreuses thérapies déclenchent ce phénomène de mort cellulaire notamment en oncologie. L’observation de ce phénomène in vivo constitue un enjeu majeur pour le diagnostic, le pronostic et le suivi des thérapies. Plusieurs
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Banks, John W. "α-fluoroamides in biotransformations". Thesis, Durham University, 2004. http://etheses.dur.ac.uk/3171/.

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Classically hydrolytic enzymes, such as lipases, are considered to exhibit selectivity at a stereogenic centre, based on the steric nature of the adjacent substituent. In this study we report on the selectivity of hydrolytic enzymes (acylase's and protease's) on compounds containing both hydrogen and fluorine atoms at the stereogenic centre. A selectivity of 96% de is reported for the hydrolysis of an α-fluoroamide using Aspergillus melleus acylase. The K,„ and Ymax values are reported for each diastereomer, which demonstrate a ten-fold preference for the {S, S)-isomer over the (S-S)-isomer. A
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Moraux, Thomas. "Synthesis and evaluation of α-fluoro analogues of capsaicin and 2-(aminomethyl)piperidine derivatives". Thesis, University of St Andrews, 2011. http://hdl.handle.net/10023/2094.

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Chapter 1 gives an overview of the fluorine chemistry field, from its early developments to recent applications in medicinal chemistry. The development of asymmetric electrophilic or nucleophilic installation of fluorine in organic molecules is highlighten. Chapter 2 of this thesis discusses the enantioselective synthesis of α-fluoroamides. The study is applied to the synthesis of fluoroenantiomers of the bioactive molecule capsaicin and short-chain analogues. The biological activity of these compounds is assayed with the TRPV1 receptor. Results show that enantioselective α-fluoroamides (R)-97
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Book chapters on the topic "Fluoroamines"

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Soloshonok, Vadim A. "Biomimetic, Reducing Agent-Free Reductive Amination of Fluorocarbonyl Compounds: Practical Asymmetric Synthesis of Enantiopure Fluoroamines and Amino Acids." In ACS Symposium Series. American Chemical Society, 1999. http://dx.doi.org/10.1021/bk-2000-0746.ch006.

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Fowden, L. "Fluoroamino Acids and Protein Synthesis." In Novartis Foundation Symposia. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470719855.ch8.

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Coenen, H. H. "Biochemistry and Evaluation of Fluoroamino Acids." In PET Studies on Amino Acid Metabolism and Protein Synthesis. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1620-6_8.

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Tsukamoto, Takashi, James K. Coward, and John J. McGuire. "Fluoroamino Acid Containing Analogues of Folic Acid and Methotrexate." In ACS Symposium Series. American Chemical Society, 1996. http://dx.doi.org/10.1021/bk-1996-0639.ch009.

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Soloshonok, V. A. "Practical Synthesis of Enantiopure Fluoroamino Acids of Biological Interest by Asymmetric Aldol Reactions." In ACS Symposium Series. American Chemical Society, 1996. http://dx.doi.org/10.1021/bk-1996-0639.ch002.

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Collier, S. J., and W. Xiang. "-Chloro--fluoroamines." In Nitro, Nitroso, Azo, Azoxy, and Diazonium Compounds, Azides, Triazenes, and Tetrazenes. Georg Thieme Verlag KG, 2010. http://dx.doi.org/10.1055/sos-sd-041-00635.

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Collier, S. J., and W. Xiang. "-Bromo--fluoroamines." In Nitro, Nitroso, Azo, Azoxy, and Diazonium Compounds, Azides, Triazenes, and Tetrazenes. Georg Thieme Verlag KG, 2010. http://dx.doi.org/10.1055/sos-sd-041-00640.

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"34.10.5 β-Fluoroamines (Update 2017)." In Knowledge Updates: 2017/2, edited by Christmann, Paquin, Weinreb, Carreira, and Schaumann. Georg Thieme Verlag, 2017. http://dx.doi.org/10.1055/sos-sd-134-00206.

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"Product Class 10: β-Fluoroamines." In Category 5, Compounds with One Carbon Heteroatom Bond, edited by Percy. Georg Thieme Verlag, 2006. http://dx.doi.org/10.1055/sos-sd-034-00262.

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Ostrowska, K., and A. Kolasa. "-Fluoroamidines from Imidoyl Fluorides and Amines." In Three Carbon-Heteroatom Bonds: Amides and Derivatives; Peptides; Lactams. Georg Thieme Verlag KG, 2005. http://dx.doi.org/10.1055/sos-sd-022-00569.

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