Academic literature on the topic 'Fluroquinolones'

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Journal articles on the topic "Fluroquinolones"

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Fitzgerald, Margaret. "The Fluroquinolones." Journal of the American Academy of Nurse Practitioners 6, no. 9 (1994): 447–49. http://dx.doi.org/10.1111/j.1745-7599.1994.tb00983.x.

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Santos, Maria de Fátima, Iris da Fátima Mariotto, Isabela Lopes Massitel, et al. "Uso das fluoroquinolonas em cães e gatos domésticos." Research, Society and Development 10, no. 9 (2021): e25110917858. http://dx.doi.org/10.33448/rsd-v10i9.17858.

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As fluoroquinolonas são drogas sintéticas que evoluíram ao longo do tempo, sendo formadas por um grupo de antibióticos desenvolvido a partir do ácido nalidíxico, contendo assim, quatro gerações com diferenças estruturais que alteram o espectro de atividade. As fluroquinolonas são utilizadas em todo o mundo no tratamento de infecções de origem bacteriana. Este estudo teve como objetivo reunir informações sobre o uso das fluoroquinolonas em cães e gatos domésticos. Para a realização desta revisão bibliográfica, foram coletados os dados do período de 2006 a 2019 na literatura disponível no Portal
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Shital, J. Patil, S. Sonawane Rushikesh, B. Tarle* Shubham, R. Gavali Siddesh, A. Pawar Akash, and V. Inamke Om. "A REVIEW BASED ON ANTIMICROBIAL ACTIVITY OF QUINOLONES AND THEIR DERIVATIVES." World Journal of Pharmaceutical Science and Research 3, no. 3 (2024): 222–39. https://doi.org/10.5281/zenodo.12640666.

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The main aim of review is to learn the antimicrobial activity of Quinolone and their derivatives and to study the type and uses of quinolones and fluroquinolones. It is done to clarify the study regarding the first generation and second-generation fluroquinolones along with its working and spectrum also, to understand the study regarding to the different type antimicrobial drugs.
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Vishwajith. "Comparison of in-vitro Antibiotic Susceptibility of Ciprofloxacin, Cefotaxime, Ceftazidime and Cefepime against Gram Negative Bacilli Infections - A Study from Tertiary Care Centre." Journal of Medical Sciences and Health 9, no. 1 (2023): 64–69. http://dx.doi.org/10.46347/jmsh.v9i1.22.369.

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Introduction: Infections from gram negative bacilli is a challenge for clinicians and laboratory personnel. Treatment of these infections remained as an area of concern. Both fluroquinolones and cephalosporins are most common choice of antibiotics. Despite Cephalosporins, being drug of choice they are expensive also showed many adverse reactions. This study, compares and reevaluates the susceptibility of gram negative bacteria to fluroquinolones (ciprofloxacin) compared to cephalosporins. Method: Various samples(pus, sputum, urine, blood and bodyfluids) were processed according to standard pro
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Jain, Deepak Kumar, Sameeksha Jain, Anjali Devi Rajpoot, Basant Khare, Sanjana Soni, and Ruchi Yadav. "Synthesis of mutual prodrug of mefenamic acid and fluroquinolones." Current Trends in Pharmacy and Pharmaceutical Chemistry 6, no. 4 (2025): 146–59. https://doi.org/10.18231/j.ctppc.2024.030.

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A novel strategy in medicinal chemistry to increase the therapeutic efficacy and reduce the side effects of separate medications is the creation of mutual prodrugs. The production and pharmacological assessment of a mutual prodrug including the broad-spectrum antibiotic class fluoroquinolones and the nonsteroidal anti-inflammatory drug (NSAID) mefenamic acid are the main topics of this paper. The justification for this combination is its ability to reduce the gastrointestinal and other systemic side effects that are frequently linked to NSAIDs and fluoroquinolones, while also potentially enhan
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Lovanshi, Kavita, Bharti Choury, and Sanjeev Ranjan. "Synthesis of Mutual Prodrug of Mefenamic Acid and Fluroquinolones." International Journal of Pharmaceutical Sciences and Medicine 9, no. 8 (2024): 39–69. http://dx.doi.org/10.47760/ijpsm.2024.v09i08.004.

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The development of mutual prodrugs is an innovative approach in medicinal chemistry aimed at enhancing the therapeutic efficacy and minimizing the adverse effects of individual drugs. This review focuses on the synthesis and pharmacological evaluation of a mutual prodrug combining mefenamic acid, a nonsteroidal anti-inflammatory drug (NSAID), and fluoroquinolones, a class of broad-spectrum antibiotics. The rationale behind this combination stems from the potential to synergistically enhance anti-inflammatory and antibacterial activities while reducing the gastrointestinal and other systemic si
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Bhattacharjee, Atanu, Baphilinia Jones Mylliemngap, and Devadasan Velmurugan. "3D-QSAR studies on fluroquinolones derivatives as inhibitors for tuberculosis." Bioinformation 8, no. 8 (2012): 379–85. http://dx.doi.org/10.6026/97320630008379.

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Bhattacharjee, Atanu, Baphilinia Jones Mylliemngap, and Devadasan Velmurugan. "3D-QSAR studies on fluroquinolones derivatives as inhibitors for tuberculosis." Bioinformation 8, no. 8 (2012): 381–87. http://dx.doi.org/10.6026/97320630008381.

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Selvam, P. "Synthesis, Anti-mycobacterial and Cytotoxicity Studies of Novel [(Sulphamoylphenyl)amino]methylpiperazinyl fluroquinolones." International Journal of Drug Design and Discovery 3, no. 3 (2025): 837–39. https://doi.org/10.37285/ijddd.3.3.2.

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A series of novel [(Sulphamoylphenyl)amino]methyl piperazinyl fluroquinolones were synthesized through modifying the N4-hydrogen of piperazine in fluoroquinolones with formaldehyde and sulphanomides by mannich reactions. Synthesized compounds were screened for anti-mycobacterial activity against TB H37Rv strain. Cytotoxicity of the synthesized compounds was also tested in mock-infected Vero cells. All the compounds exhibited significant anti-tubercular activity. Among the synthesized compounds, compounds GF-SA, GF-SD and CF-SD were found to exhibit the most potent in vitro anti-mycobacterial a
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Sah, MK, SK Mishra, T. Kirikae, JB Sherchan, BP Rijal, and BM Pokhrel. "Nosocomial Bacterial Infection and Antimicrobial Resistant Pattern in a Tertiary care Hospital in Nepal." Journal of Institute of Medicine Nepal 36, no. 3 (2014): 38–48. http://dx.doi.org/10.59779/jiomnepal.567.

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Introduction: Nosocomial infection is a global problem with multi facet outcomes. At present, the emergence of resistance to antimicrobial agents is a global public health problem which is well pronounced in developing countries. Methods: The aim of this study was to determine the prevalence of bacteria causing nosocomial infections and their antibiotics resistant pattern among the patients admitted at Tribhuvan University Teaching Hospital (TUTH), Kathmandu, Nepal. The study was conducted during a period of March 2011 to February 2012. Nine hundred clinical specimens which included urine, spu
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Book chapters on the topic "Fluroquinolones"

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Farzin, Anika, Md Mizanur Rahman, and Ferdows Ara Mollika. "Pseudomonas aeruginosa: The Alarming Pathogen of Hospital Acquired Infection." In Pseudomonas aeruginosa - New Perspectives and Applications [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.110249.

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Pseudomonas aeruginosa is a Gram-negative bacillus that is ubiquitous. It is found in abundant amount in the environment, especially in moist places. Immunocompetent persons get less infected by P. aeruginosa, while immunocompromised patients get more infected by them. The burn patients, patients with cystic fibrosis, and patients who are dependent on any device like ventilator, intravenous catheter, or indwelling bladder catheter are more prone to acquire the infection. It is the main cause of ventilator-associated pneumonia. Patients with neutropenia are more susceptible to P. aeruginosa inf
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