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1

Fitzgerald, Margaret. "The Fluroquinolones." Journal of the American Academy of Nurse Practitioners 6, no. 9 (1994): 447–49. http://dx.doi.org/10.1111/j.1745-7599.1994.tb00983.x.

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2

Santos, Maria de Fátima, Iris da Fátima Mariotto, Isabela Lopes Massitel, et al. "Uso das fluoroquinolonas em cães e gatos domésticos." Research, Society and Development 10, no. 9 (2021): e25110917858. http://dx.doi.org/10.33448/rsd-v10i9.17858.

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As fluoroquinolonas são drogas sintéticas que evoluíram ao longo do tempo, sendo formadas por um grupo de antibióticos desenvolvido a partir do ácido nalidíxico, contendo assim, quatro gerações com diferenças estruturais que alteram o espectro de atividade. As fluroquinolonas são utilizadas em todo o mundo no tratamento de infecções de origem bacteriana. Este estudo teve como objetivo reunir informações sobre o uso das fluoroquinolonas em cães e gatos domésticos. Para a realização desta revisão bibliográfica, foram coletados os dados do período de 2006 a 2019 na literatura disponível no Portal
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3

Shital, J. Patil, S. Sonawane Rushikesh, B. Tarle* Shubham, R. Gavali Siddesh, A. Pawar Akash, and V. Inamke Om. "A REVIEW BASED ON ANTIMICROBIAL ACTIVITY OF QUINOLONES AND THEIR DERIVATIVES." World Journal of Pharmaceutical Science and Research 3, no. 3 (2024): 222–39. https://doi.org/10.5281/zenodo.12640666.

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The main aim of review is to learn the antimicrobial activity of Quinolone and their derivatives and to study the type and uses of quinolones and fluroquinolones. It is done to clarify the study regarding the first generation and second-generation fluroquinolones along with its working and spectrum also, to understand the study regarding to the different type antimicrobial drugs.
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Vishwajith. "Comparison of in-vitro Antibiotic Susceptibility of Ciprofloxacin, Cefotaxime, Ceftazidime and Cefepime against Gram Negative Bacilli Infections - A Study from Tertiary Care Centre." Journal of Medical Sciences and Health 9, no. 1 (2023): 64–69. http://dx.doi.org/10.46347/jmsh.v9i1.22.369.

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Introduction: Infections from gram negative bacilli is a challenge for clinicians and laboratory personnel. Treatment of these infections remained as an area of concern. Both fluroquinolones and cephalosporins are most common choice of antibiotics. Despite Cephalosporins, being drug of choice they are expensive also showed many adverse reactions. This study, compares and reevaluates the susceptibility of gram negative bacteria to fluroquinolones (ciprofloxacin) compared to cephalosporins. Method: Various samples(pus, sputum, urine, blood and bodyfluids) were processed according to standard pro
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Jain, Deepak Kumar, Sameeksha Jain, Anjali Devi Rajpoot, Basant Khare, Sanjana Soni, and Ruchi Yadav. "Synthesis of mutual prodrug of mefenamic acid and fluroquinolones." Current Trends in Pharmacy and Pharmaceutical Chemistry 6, no. 4 (2025): 146–59. https://doi.org/10.18231/j.ctppc.2024.030.

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A novel strategy in medicinal chemistry to increase the therapeutic efficacy and reduce the side effects of separate medications is the creation of mutual prodrugs. The production and pharmacological assessment of a mutual prodrug including the broad-spectrum antibiotic class fluoroquinolones and the nonsteroidal anti-inflammatory drug (NSAID) mefenamic acid are the main topics of this paper. The justification for this combination is its ability to reduce the gastrointestinal and other systemic side effects that are frequently linked to NSAIDs and fluoroquinolones, while also potentially enhan
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Lovanshi, Kavita, Bharti Choury, and Sanjeev Ranjan. "Synthesis of Mutual Prodrug of Mefenamic Acid and Fluroquinolones." International Journal of Pharmaceutical Sciences and Medicine 9, no. 8 (2024): 39–69. http://dx.doi.org/10.47760/ijpsm.2024.v09i08.004.

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The development of mutual prodrugs is an innovative approach in medicinal chemistry aimed at enhancing the therapeutic efficacy and minimizing the adverse effects of individual drugs. This review focuses on the synthesis and pharmacological evaluation of a mutual prodrug combining mefenamic acid, a nonsteroidal anti-inflammatory drug (NSAID), and fluoroquinolones, a class of broad-spectrum antibiotics. The rationale behind this combination stems from the potential to synergistically enhance anti-inflammatory and antibacterial activities while reducing the gastrointestinal and other systemic si
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7

Bhattacharjee, Atanu, Baphilinia Jones Mylliemngap, and Devadasan Velmurugan. "3D-QSAR studies on fluroquinolones derivatives as inhibitors for tuberculosis." Bioinformation 8, no. 8 (2012): 379–85. http://dx.doi.org/10.6026/97320630008379.

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8

Bhattacharjee, Atanu, Baphilinia Jones Mylliemngap, and Devadasan Velmurugan. "3D-QSAR studies on fluroquinolones derivatives as inhibitors for tuberculosis." Bioinformation 8, no. 8 (2012): 381–87. http://dx.doi.org/10.6026/97320630008381.

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9

Selvam, P. "Synthesis, Anti-mycobacterial and Cytotoxicity Studies of Novel [(Sulphamoylphenyl)amino]methylpiperazinyl fluroquinolones." International Journal of Drug Design and Discovery 3, no. 3 (2025): 837–39. https://doi.org/10.37285/ijddd.3.3.2.

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A series of novel [(Sulphamoylphenyl)amino]methyl piperazinyl fluroquinolones were synthesized through modifying the N4-hydrogen of piperazine in fluoroquinolones with formaldehyde and sulphanomides by mannich reactions. Synthesized compounds were screened for anti-mycobacterial activity against TB H37Rv strain. Cytotoxicity of the synthesized compounds was also tested in mock-infected Vero cells. All the compounds exhibited significant anti-tubercular activity. Among the synthesized compounds, compounds GF-SA, GF-SD and CF-SD were found to exhibit the most potent in vitro anti-mycobacterial a
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10

Sah, MK, SK Mishra, T. Kirikae, JB Sherchan, BP Rijal, and BM Pokhrel. "Nosocomial Bacterial Infection and Antimicrobial Resistant Pattern in a Tertiary care Hospital in Nepal." Journal of Institute of Medicine Nepal 36, no. 3 (2014): 38–48. http://dx.doi.org/10.59779/jiomnepal.567.

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Introduction: Nosocomial infection is a global problem with multi facet outcomes. At present, the emergence of resistance to antimicrobial agents is a global public health problem which is well pronounced in developing countries. Methods: The aim of this study was to determine the prevalence of bacteria causing nosocomial infections and their antibiotics resistant pattern among the patients admitted at Tribhuvan University Teaching Hospital (TUTH), Kathmandu, Nepal. The study was conducted during a period of March 2011 to February 2012. Nine hundred clinical specimens which included urine, spu
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11

Islam, Baishakhi, Mitun Kumar Paul, Afroza Akbar Sweety, et al. "Current trends in prescribing antimicrobial drugs on patients suffering from ENT infection in a teaching hospital in Khulna." Journal of Dhaka Medical College 27, no. 2 (2020): 155–60. http://dx.doi.org/10.3329/jdmc.v27i2.45828.

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Background: Inappropriate use of antimicrobials results in development of resistance to antibiotics.
 Aims and objectives: The present study was aimed at evaluating the current trends in prescribing antimicrobials in patient sufferings from ENT infection.
 Methods: A descriptive cross sectional study was carried out at ENT out-patient department of Khulna Medical College Hospital for three months in which data were collected from 500 prescriptions in customized proforma and analyzed using the World Health Organization (WHO) prescribing indicators.
 Results: Majority of the patie
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12

Boxall, Megan D., Martin R. Day, David R. Greig, and Claire Jenkins. "Antimicrobial resistance profiles of diarrhoeagenic Escherichia coli isolated from travellers returning to the UK, 2015–2017." Journal of Medical Microbiology 69, no. 7 (2020): 932–43. http://dx.doi.org/10.1099/jmm.0.001214.

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Introduction. Diarrhoeagenic Escherichia coli (DEC) are difficult to distinguish from non-pathogenic commensal E. coli using traditional culture methods. The implementation of PCR targeting specific virulence genes characteristic of the five DEC pathotypes, has improved the detection of DEC in faecal specimens from patients with symptoms of gastrointestinal disease. Aim. Antimicrobial resistance (AMR) profiles of 660 strains of DEC isolated between 2015 and 2017 from UK travellers reporting symptoms of gastrointestinal disease were reviewed to look for evidence of emerging AMR associated with
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13

Neeraj, Srivastav, Goel Mani, Kaushik Sadhna, and Kumar Vinay. "Fixed Drug Eruption: A Case Series." International Journal of Toxicological and Pharmacological Research 14, no. 8 (2024): 69–73. https://doi.org/10.5281/zenodo.13827773.

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<strong>Background and Objectives:&nbsp;</strong>Fixed Drug Eruption (FDE), is a mucocutaeous eruption occurring as a part of adverse drug reaction. They are often localised, well defined, and reoccur on the same sites upon restarting the drug. Here, we are reporting a case series of 309 patients who developed FDE after consuming these commonly used drugs.&nbsp;<strong>Methods:</strong>&nbsp;This study was conducted at the dermatology outpatient department (OPD) in collaboration with the Adverse Drug Reaction (ADR) Monitoring Centre of the pharmacology department of MLB Medical College, Jhansi
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Rajendran, Harish Kumar, Mohammed Askkar Deen Fakrudeen, Ragavan Chandrasekar, Eric D. van Hullebusch, and Padmanaban Velayudhaperumal Chellam. "Electrocatalytic removal of fluroquinolones from simulated pharmaceutical effluent: Chemometric analysis, chemical blueprint of electrodes and generated sludge." Environmental Research 195 (April 2021): 110844. http://dx.doi.org/10.1016/j.envres.2021.110844.

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15

Rahme, Christine, Helen Jacoby, Karen Whalen, and Lisa Avery. "765Impact of a Hospital Based Antibiotic Stewardship Team on Prescribing Fluroquinolones at a Long Term Care Facility." Open Forum Infectious Diseases 1, suppl_1 (2014): S216. http://dx.doi.org/10.1093/ofid/ofu052.473.

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16

Li, Dandan, Tiansheng Wang, Su Shen, et al. "Effects of Fluroquinolones in Newly Diagnosed, Sputum-Positive Tuberculosis Therapy: A Systematic Review and Network Meta-Analysis." PLOS ONE 10, no. 12 (2015): e0145066. http://dx.doi.org/10.1371/journal.pone.0145066.

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17

SAFILA, NAVEED, UROOG SHEEBA, and WAHEED NIMRA. "ASSAY OF MOXIFLOXACIN BRANDS." International Journal of Current Pharmaceutical Review and Research 6, no. 1 (2015): 22–27. https://doi.org/10.5281/zenodo.12687945.

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Moxifloxacin is a fourth generation fluroquinolones synthetic antibacterial agent. Moxifloxacin activeagainst gram positive and gram negative bacteria. Many oral and parentral preparation of moxifloxacin areused to treat the many respiratory and skin infections. In this study, a quick and simple assay method hasbeen developed by using the UV spectrophotometer. The assay of different brands of moxifloxacin isbased on measuring the absorbance at the 294 nm wave length .Moxiget , avolox and izilone threedifferent brands of moxifloxacin are taken from the market . 200 ppm, 100ppm, 50ppm and 25ppms
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18

Tascini, Carlo. "Antibiotic stewardship: ripartiamo dalla pratica clinica." Urologia Journal 85, no. 1_suppl (2018): S20—S23. http://dx.doi.org/10.1177/0391560318770093.

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Antibiotic stewardship: a milestone in everyday clinical practice Infectious diseases caused by multi-resistant pathogens are increasing worldwide and are challenging for clinicians, also in urological setting. The alarming situation is worsened by the limited perspective of new antibiotic developments. Several authors demonstrated that in Italy we have alarming data about resistance rates: in Campania about 58% of Escherichia coli are resistant to fluroquinolones, as 46% to sulfamethoxazole-trimethoprim. On the other hand, the resistance rate against fosfomycin is still low less than 5%. More
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19

Intra, Jari, Davide Carcione, Roberta Maria Sala, Claudia Siracusa, Paolo Brambilla, and Valerio Leoni. "Antimicrobial Resistance Patterns of Enterobacter cloacae and Klebsiella aerogenes Strains Isolated from Clinical Specimens: A Twenty-Year Surveillance Study." Antibiotics 12, no. 4 (2023): 775. http://dx.doi.org/10.3390/antibiotics12040775.

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We retrospectively analyzed the antimicrobial data of Enterobacter spp. strains isolated from hospitalized subjects and outpatients over 20 years (2000–2019). A total of 2277 non-duplicate Enterobacter spp. isolates, 1037 from outpatients (45%) and 1240 from hospitalized subjects (55%), were retrieved. Most of samples are infections of the urinary tract. Considering Enterobacter aerogenes, now classified as Klebsiella aerogenes, and Enterobacter cloacae, representing more than 90% of all isolates, except for aminoglycosides and fluroquinolones, which showed significant antibiotic decreasing tr
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20

Ryan, Tenley, Neena Thomas-Gosain, Jane Eason, Hanna Akalu, Navila Sharif, and Jessica Bennett. "Evaluation of periprocedure antibiotics and infection-related hospitalizations after transrectal prostate biopsies." Antimicrobial Stewardship & Healthcare Epidemiology 2, S1 (2022): s71. http://dx.doi.org/10.1017/ash.2022.193.

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Background: Prostate cancer is the leading cancer diagnosis and the second leading cause of cancer deaths in men. Definitive diagnosis is made by prostate biopsy. This procedure poses a risk of infection and, rarely, sepsis. Studies have found the incidence of symptomatic urinary tract infection (UTI) after biopsy to be 2%–3%, and the rate of infection-related hospitalization (IRH) to be 0.6%–4.1%. An initial review at our facility found the IRH rate to be 3.7%. The primary purpose of this study was to determine the incidence of IRH following prostate biopsy in patients at the Memphis VA Medic
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21

Ndiaye, A. Guèye, Hounkponou Edwige, Fatou Bintou Guèye, and Cheikh Saad Bouh Boye. "Trend in Antibiotic Resistance of Streptococcus Pneumoniae and Haemophilus Influenzae Strains Isolated from Community Acquired Respiratory Tract Infections in Dakar, Senegal between 2005 and 2008." Microbiology Insights 3 (January 2010): MBI.S3819. http://dx.doi.org/10.4137/mbi.s3819.

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Development of antibiotic resistance among common respiratory pathogens is a major cause of concern worldwide. Streptococcus pneumoniae and Haemophilus influenzae are among the most common respiratory pathogens. In this study, representative samples obtained from 3 different medical centers in Dakar, Senegal were subjected to antibiotic susceptibility testing. The samples were collected from 2005 to 2008 and the data obtained was compared to establish resistance patterns between the two years (i.e. 2005–2006 to 2007–2008). S. pneumoniae exhibited a significant increase in the resistance to azi
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22

Villanueva, Juan, David Nix, Rachana Bhattarai, Kenneth Komatsu, and Elizabeth Kim. "Antimicrobial Stewardship Approach: Strategy to Enhance Antimicrobial Stewardship Programs in Arizona Long-Term Care." Infection Control & Hospital Epidemiology 41, S1 (2020): s122—s123. http://dx.doi.org/10.1017/ice.2020.631.

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Background: Implementing robust antimicrobial stewardship programs within long-term care facilities (LTCFs) presents unique challenges not typically seen in other healthcare settings. These facilities tend to care for older adults, rely on limited on-site clinician availability and experience higher-than-normal staff turnover. Many LTCFs lack the resources and expertise to track and analyze antibiotics usage. Through a collaborative effort between the Arizona Department of Health Services and the University of Arizona College of Pharmacy, support for carrying out stewardship activities was pro
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Medler, Corey, Nicholas Mercuro, Helina Misikir, et al. "Patterns of Oral Antibiotic Use and Excess Duration at Hospital Discharge." Infection Control & Hospital Epidemiology 41, S1 (2020): s522—s523. http://dx.doi.org/10.1017/ice.2020.1206.

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Background: Antimicrobial stewardship (AMS) interventions have predominantly involved inpatient antimicrobial therapy. However, for many hospitalized patients, most antibiotic use occurs after discharge, and unnecessarily prolonged courses of therapy are common. Patient transition from hospitalization to discharge represents an important opportunity for AMS intervention. We describe patterns of antibiotic use selection and duration of therapy (DOT) for common infections including discharge antibiotics. Methods: This retrospective cross-sectional analysis was derived from an IRB-approved, multi
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Lai, Chih-Cheng, Ya-Hui Wang, Kuang-Hung Chen, Chao-Hsien Chen, and Cheng-Yi Wang. "The Association between the Risk of Aortic Aneurysm/Aortic Dissection and the Use of Fluroquinolones: A Systematic Review and Meta-Analysis." Antibiotics 10, no. 6 (2021): 697. http://dx.doi.org/10.3390/antibiotics10060697.

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This study aimed to investigate the association between the risk of aortic aneurysm (AA)/aortic dissection (AD) and the use of fluoroquinolones (FQs). PubMed, Embase, Cochrane CENTRAL, Cochrane Database of Systematic Reviews, Web of Science and Scopus were searched for relevant articles to 21st February 2021. Studies that compared the risk of AA/AD in patients who did and did not receive FQs or other comparators were included. The pooled results of nine studies with 11 study cohorts showed that the use of FQs increased the risk of AA/AD by 69% (pooled risk ratio (RR) = 1.69 (95% CI = 1.08, 2.6
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Hathurusinghe, Madhavi H., Ruwan C. Gunasena, and Preeni Abeynayake. "A SIX PLATE MICROBIOLOGICAL ASSAY FOR SCREENING OF ANTIMICROBIAL RESIDUES IN FOOD OF ANIMAL ORIGIN." International Journal of Research -GRANTHAALAYAH 8, no. 11 (2020): 22–28. http://dx.doi.org/10.29121/granthaalayah.v8.i11.2020.2069.

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Occurrence of antimicrobial residues in livestock and aquatic products is a current public health concern. The monitoring of food commodities for antimicrobial residues will ensure the consumer safety and promote trade. Therefore, the objective of this study was to establish a screening test to detect antimicrobial residues in food of animal origin. A bioassay consists of six plates was established, which enables screening of six groups of antimicrobials, namely; penicillins, sulphonamides, streptomycin, erythromycin, tetracyclines and fluroquinolones. The Six Plate Test (SPT) is a bioassay te
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C. H., Janaki Devi, Seethalakshmi S., and Devaraj S. "Drug utilization study in ophthalmology out patients in a tertiary care teaching hospital." International Journal of Basic & Clinical Pharmacology 9, no. 11 (2020): 1721. http://dx.doi.org/10.18203/2319-2003.ijbcp20204501.

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Background: The objective of the study was to evaluate the utilization of the drugs in the ophthalmology outpatient department.Methods: Present study was conducted at ESIC medical college &amp; PGIMSR Ophthalmology Department. Total 700 prescriptions were collected from 700 patients and prescriptions were analysed for total and average number drugs per prescription, duration of treatment, dosage form, drug encounter with antibiotics and other group of drugs also percentage of drugs prescribed by generic names.Results: After analysing the prescriptions, average number of drugs per prescription
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27

Sriaroon, Chakrapol, John N. Greene, Albert L. Vincent, Veronica T. Tucci, Mohamed A. Kharfan-Dabaja, and Ramon Sandin. "BK virus: microbiology, epidemiology, pathogenesis, clinical manifestations and treatment." Asian Biomedicine 4, no. 1 (2010): 3–18. http://dx.doi.org/10.2478/abm-2010-0002.

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Abstract Background: BK virus infection is common but is usually asymptomatic. However, it can become life threatening as severe hemorrhagic cystitis (HC) or the polyomavirus-associated nephropathy (PVAN) particularly in immune compromised and transplant recipients. Some investigators have studied the pathophysiology and there are anecdotal and uncontrolled studies of therapy with few conclusions allowing treatment guidelines. Objectives: Summarize literature review of current knowledge concerning the nature, epidemiology, pathophysiology, diagnosis and treatment of this common virus infection
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Ndiaye, Aissatou Geuye, Cheikh Saadbou Boye, Edwige Hounkponou, Fatou Bintou Gueye, and Aida Badiane. "Antimicrobial susceptibility of select respiratory tract pathogens in Dakar, Senegal." Journal of Infection in Developing Countries 3, no. 09 (2009): 660–66. http://dx.doi.org/10.3855/jidc.20.

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Background : Haemophilus influenzae, Moraxella catarrhalis, Streptococcus pyogenes, and Streptococcus pneumoniae are the most common causative agents of respiratory tract infections (RTIs). The increase in resistance to current antibacterial agents highlights the need to monitor the resistance pattern of these bacterial pathogens. Methodology: In this study, we assessed the antibacterial susceptibility of these pathogens causing respiratory tract infections in Dakar, Senegal, during 2007-2008. A total of 290 bacterial isolates (75 H. influenzae, 10 M. catarrhalis, 105 S. pneumoniae, and 100 S.
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Vikramjeet, Singh, Batta Angelika, and Malik Nishtha. "Norfloxacin Induced Recurrent Fixed Drug Eruption in a self Treated Adult Female Patient - A Case Report." Current Drug Safety 14, no. 1 (2019): 72–76. http://dx.doi.org/10.2174/1574886313666180807095559.

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Background: Fixed drug eruption is a clinical entity occurring at the same site each time the drug is administered. They are usually found on lips, genitalia, abdomen, and legs but can occur at any location. The eruptions usually occur within hours of administration of the drug and resolves spontaneously. Most common drugs causing them include antimicrobials. Fluroquinolones especially norfloxacin is commonly used in the treatment of gastrointestinal infections. Cutaneous adverse drug reactions are very rare with norfloxacin. Case Report: In this case report, a young female, soon after taking
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30

Panta, Usha. "Utilization Of Antibiotics In Patients With Urinary Tract Infections." INDONESIAN JOURNAL OF HEALTH SCIENCES RESEARCH AND DEVELOPMENT (IJHSRD) 4, no. 2 (2022): 38–48. http://dx.doi.org/10.36566/ijhsrd/vol4.iss2/130.

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Objectives: This study aims to investigate the utilization of antibiotics among the patients attending in Silverline Hospital, Lekhnath Marg, Balaju, Kathmandu-44600, Nepal. Methods: A hospital based cross sectional study was conducted in between June to September, 2022. A standard questionnaire was prepared, to conduct the survey based on patient’s demographic data such as which utilization of drug, age, gender, therapy and medication. Results: Out of 111 patients, antibiotics Levofloxacin is highly prescribed to the patients. It is prescribed to 92 (82.90%) people. Cefixime is prescribed for
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Addison, Naa Okaikor, Albert Paintsil, and Mercy Jemima Newman. "Changes In Bacterial Flora Of Burn Wounds And Their Antibiotic Susceptibility Patterns At A Tertiary Hospital In Ghana." Postgraduate Medical Journal of Ghana 12, no. 2 (2023): 55–59. http://dx.doi.org/10.60014/pmjg.v12i2.319.

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Objective: To determine the time-related changes in burn wound bacteria and to determine the antibiotic susceptibilities of these bacteria. Methodology: The study was carried out over a 4-month period from September 2017 at the Burns Unit of the Korle-Bu Teaching Hospital in Accra. Wound swabs were taken weekly from burn patients on admission and each patient was followed-up for a month. The swabs were cultured, and antibiotic susceptibility testing done on isolated pathogens. Results: A total of 214 wound swabs were taken from 59 patients enrolled with an overall isolation rate of 65%. Gram n
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Jorige, Archana, Lohitha B., and Lavanya S. L. "A cross sectional study on prescribing pattern for children at primary health care clinics." International Journal Of Community Medicine And Public Health 7, no. 8 (2020): 3149. http://dx.doi.org/10.18203/2394-6040.ijcmph20203392.

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Background: Rational prescribing for pediatrics is very essential as there is increased risk from the use of medicines in them due to multiple reasons ranging from altered pharmacokinetics to long-term side effects. Drug related needs of children must be assessed on individual basis to meet appropriate health care out comes. This cross-sectional descriptive study aimed at assessing drug use pattern and rationality in prescribing pattern as per World Health Organization (WHO) core prescribing indicators.Methods: A cross-sectional and prospective study was carried out in private primary health c
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Vilaró, Anna, Elena Novell, Vicens Enrique-Tarancon, Jordi Balielles, Lourdes Migura-García, and Lorenzo Fraile. "Antimicrobial Susceptibility Testing of Porcine Bacterial Pathogens: Investigating the Prospect of Testing a Representative Drug for Each Antimicrobial Family." Antibiotics 11, no. 5 (2022): 638. http://dx.doi.org/10.3390/antibiotics11050638.

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Antimicrobial susceptibility testing is necessary to carry out antimicrobial stewardship but a limited number of drugs belonging to each antimicrobial family has to be tested for technical limitations and economic resources. In this study, we have determined the minimal inhibitory concentration, using microdilution following international standards (CLSI), for 490 Actinobacillus pleuropneumoniae, 285 Pasteurella multocida, 73 Bordetella bronchiseptica, 398 Streptococcus suis and 1571 Escherichia coli strains from clinical cases collected in Spain between 2018 and 2020. The antimicrobial suscep
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Papadopoulos, Dimitrios, Evanthia Petridou, Konstantinos Papageorgiou, et al. "Phenotypic and Molecular Patterns of Resistance among Campylobacter coli and Campylobacter jejuni Isolates, from Pig Farms." Animals 11, no. 8 (2021): 2394. http://dx.doi.org/10.3390/ani11082394.

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The purpose of this research was to characterize the antibiotic resistance patterns of Campylobacter spp. isolated from commercial farrow to finish farms in Greece, and analyze the relevant molecular resistance mechanisms among the resistant Campylobacter isolates. Susceptibility testing to five different classes of antibiotics was performed in 100 C. coli and 100 C. jejuni, previously isolated and identified. All isolates were found susceptible to meropenem. Very high rates of resistance were recorded for tetracyclines (84.5%), medium rates of resistance were recorded regarding quinolones (23
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Kakati, Barnali, Nupur Koul, Sonika Agarwal, and Garima Mittal. "Multidrug resistant Acinetobacter baumannii causing Ventilator associated respiratory infections at a tertiary care center of India." IP International Journal of Medical Microbiology and Tropical Diseases 8, no. 1 (2022): 15–18. http://dx.doi.org/10.18231/j.ijmmtd.2022.004.

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A rise in Multidrug resistant causing ventilator-associated respiratory infections (VARIs) is posing a therapeutic challenge for physicians and diagnosticians worldwide. Timely detection and reporting of these robust multidrug resistant (MDR) pathogens would be useful in not only guiding an appropriate empirical therapy but also in controlling the spread of these drug resistant strains in the ICUs and hospital. : To detect in Endotracheal secretions of suspected cases of Ventilator-associated respiratory infections (VARIs) and report the antimicrobial sensitivity pattern for the same. : Observ
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Qekwana, Daniel Nenene, Agricola Odoi, and James Wabwire Oguttu. "Efficacy Profiles of Antimicrobials Evaluated against Staphylococcus Species Isolated from Canine Clinical Specimens." Animals 11, no. 11 (2021): 3232. http://dx.doi.org/10.3390/ani11113232.

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Cross-resistance occurs between antimicrobials with either similar mechanisms of action and/or similar chemical structures, or even between unrelated antimicrobials. This study employed a multivariate approach to investigate the associations between the efficacy profile of antimicrobials and the clustering of eleven different antimicrobial agents based on their efficacy profile. Records of the susceptibility of 382 confirmed Staphylococcus species isolates against 15 antimicrobials based on the disc diffusion method were included in this study. Tetrachoric correlation coefficients were compute
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Butov, D., C. Lange, J. Heyckendorf, et al. "Multidrug-resistant tuberculosis in the Kharkiv Region, Ukraine." International Journal of Tuberculosis and Lung Disease 24, no. 5 (2020): 485–91. http://dx.doi.org/10.5588/ijtld.19.0508.

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OBJECTIVE: To document the level of drug resistance in MDR-TB patients and to characterize management capacities for their medical care and MDR-TB treatment outcomes in the Kharkiv region of Ukraine. This area has one of the highest frequencies of MDR-TB worldwide.METHODS: A retrospective observational cohort study was performed on registry data from the regional anti-TB dispensary in Kharkiv. All microbiologically confirmed MDR-TB patients registered in 2014 were included. Diagnostic, treatment and post-treatment follow-up data were analysed.RESULTS: Of 169 patients with MDR-TB, 55.0% had pre
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Ashrafuzzaman, Mohammad, Mohammod Asaduzzaman, Montosh Kumar Mondal, et al. "Prevalence and Pattern of Antimicrobial Resistance in ICU Patients with Sepsis in Dhaka City: A Single Center Study." EAS Journal of Anaesthesiology and Critical Care 6, no. 06 (2024): 151–58. https://doi.org/10.36349/easjacc.2024.v06i06.007.

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Background: Pathogenic resistance against antibiotics is substantially mounting in the developing countries including Bangladesh. Antimicrobial resistance is a rising concern specially among the critically ill patients who are often treated by multiple antibiotics. Objective: To observe the pattern of antimicrobial resistance among the patients diagnosed with sepsis admitted into the intensive care unit (ICU). Method: This observational study took place in the ICU of Bangabandhu Sheikh Mujib Medical University for 1 year. Samples of blood, urine, tracheal aspirate were obtained from 192 patien
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Thamarai, Selvi V.T., A.S. Smiline Girija, and J. Vijayashree Priyadharsini. "Co-occurrence of bap gene among multi-drug resistant strains of Acinetobacter baumannii from India." ACTA MICROBIOLOGICA HELLENICA 66, no. 2-3 (2022): 145–54. https://doi.org/10.5281/zenodo.10077330.

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bapAb-associated biofilm formation in Acinetobacter baumannii enhances the virulence properties and highly influences the pattern of drug susceptibility among hospitalized patients. This study thus aims to molecularly characterize bapAb gene and to evaluate its co-occurrence among the multidrug-resistant (MDR) strains of A. baumannii. Semi-quantitative adherent bioassay was performed to detect the biofilm formation by 73 MDR strains of A. baumannii. Genomic DNA was further extracted and screened for bapAb by PCR followed by sequencing of the amplicons from representative strains. Pearson corre
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Hsueh, P. R. "Fluroquinolone-resistant Gonorrhea." International Journal of Infectious Diseases 12 (December 2008): e39. http://dx.doi.org/10.1016/j.ijid.2008.05.146.

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Sigdel, Brihaspati, and Sanjib Mani Regmi. "The Shift of Bacterial Sensitivity with Antibiotics in Acute Tonsillitis." Journal of Nobel Medical College 10, no. 1 (2021): 3–6. http://dx.doi.org/10.3126/jonmc.v10i1.37807.

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Correction: The second author, Sanjib Mani Regmi, was added to the website version on 13th August 2021. It omitted by mistake. The PDF of the article was correct. Background: The infection of tonsil may occur primarily or secondarily as a result of upper respiratory tract infection, usually preceded by a viral infection. Bacterial tonsillitis is most commonly caused by Streptococcus pyogenes. Penicillin remains the treatment of choice for S. pyogenes tonsillitis. The present study aimed to identify the bacterial pathogen in acute tonsillitis and their sensitivity to antibiotics. Material and M
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Bhaveshaikh, Nachiket, Sangita Sukumaran, and Upal Vyas. "Drug prescribing pattern in acute gastroenteritis in an in-patient setting in a private hospital." International Journal of Research in Medical Sciences 5, no. 4 (2017): 1256. http://dx.doi.org/10.18203/2320-6012.ijrms20170953.

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Background: Diarrheal diseases cause significant morbidity in developing countries and are the leading cause of death in children. The study was undertaken to assess drug utilization patterns in patients with gastroenteritis in a private setting.Methods: The in-patient data records of 208 patients (96 males, 112 females) admitted with acute gastroenteritis in a private hospital in Mumbai over 2 years were analysed. WHO core drug prescribing indicators - average number of drugs per prescription, percentage of drugs prescribed by generic name, percentage of encounters resulting in prescription o
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Rahman, Mustafa Sofiur, Ritu Garg, Varsha A. Singh та Dipankar Biswas. "Antibiotic susceptibility profile and extended spectrum β-lactamases production by uropathogenic Escherichia coli from tertiary care hospital of rural settings". International Journal of Research in Medical Sciences 6, № 12 (2018): 4022. http://dx.doi.org/10.18203/2320-6012.ijrms20184901.

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Background: Escherichia coli are the most common cause of urinary tract infections in community as well as hospital settings. Emergence of drug resistance in Escherichia coli due to various mechanisms makes the treatment options very limited. This study was undertaken to detect ESBLs in uropathogenic Escherichia coli isolates and to determine their antimicrobial susceptibility pattern in rural setting.Methods: A prospective study was done on 502 E. coli isolates from clinically suspected cases of urinary tract infections (UTI) patients of all age groups. All samples were inoculated on Cysteine
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S., Shanmugapriya, Saravanan T., and Janani K. "Antibiotic sensitivity pattern to urinary tract infections in a tertiary care hospital in South India." International Journal of Basic & Clinical Pharmacology 6, no. 6 (2017): 1445. http://dx.doi.org/10.18203/2319-2003.ijbcp20172239.

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Background: Urinary tract infection (UTI) is one of the most common bacterial illnesses and hence one of the most important indications for antibiotic treatment. Current knowledge of the common organisms implicated in causing UTI in the local community and surveillance to monitor the changes in susceptibility of uropathogens are imperative to ensure appropriate therapy. The study objectives were to assess the proportion of UTI caused by each of the common urinary pathogens, to study the antibiotic drug sensitivity patterns by analyzing the culture and sensitivity reports and to identify the dr
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Pise, Nitin D., and Swapnil B. Kaikade. "Analysis of prescribing pattern of antimicrobial agents and its rationality in tertiary care rural setup of Central India." International Journal of Basic & Clinical Pharmacology 6, no. 9 (2017): 2289. http://dx.doi.org/10.18203/2319-2003.ijbcp20173761.

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Background: Antimicrobial agents are most commonly prescribed drug and share major cost of the treatment. Excessive and inappropriate use of antimicrobial has become a global problem, resulting not only in substantial economic burden on healthcare system but also in contributing to the selective pressure favoring the emergence of antibiotic-resistant microorganisms. Antimicrobial agents which one uses for prophylactic, empiric and therapeutic purposes, depends upon the local epidemiology of infectious diseases, microbiology and resistance pattern as well as local clinical experience. Rational
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Klompas, Michael, Ken Kleinman, and Michael V. Murphy. "Descriptive Epidemiology and Attributable Morbidity of Ventilator-Associated Events." Infection Control & Hospital Epidemiology 35, no. 5 (2014): 502–10. http://dx.doi.org/10.1086/675834.

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Objective.The Centers for Disease Control and Prevention implemented new surveillance definitions for ventilator-associated events (VAEs) in January 2013. We describe the epidemiology, attributable morbidity, and attributable mortality of VAEs.Design.Retrospective cohort study.Setting.Academic tertiary care center.Patients.All patients initiated on mechanical ventilation between January 1, 2006, and December 31, 2011.Methods.We calculated and compared VAE hazard ratios, antibiotic exposures, microbiology, attributable morbidity, and attributable mortality for all VAE tiers.Results.Among 20,356
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Joshi, Bindira, Santosh Kumar Yadav, Manju Shree Shakya Hada, et al. "Post-Transplant Fecal Carriage of Antibiotic Resistant and ?-Lactamases-Producing Enterobacteriales among Renal Transplant Recipients." Journal of Nepal Health Research Council 21, no. 4 (2024): 578–86. http://dx.doi.org/10.33314/jnhrc.v21i4.4801.

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Background: The intestinal colonization and transmission of antibiotic-resistant Enterobacteriales to renal transplant recipients may pose a threat to them because they are profoundly immunocompromised and vulnerable to infection. Hence, it is crucial to identify these antibiotic-resistant fecal Enterobacteriales harboring high-risk populations. The objective of this study was to determine antibiotic resistance as well as ?-lactamases production in fecal Enterobacteriales among renal transplant recipients.Methods: The stool samples, one collected from each transplant recipient, were processed
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Nwala, Chuks G., Oluchi M. Izuka, Ifeyinwa Roseann Chidomere, Ikechukwu Frank Ogbonna, Ichie Eziyi Kalu, and Ihuoma Kathleen Ukpabi. "Drug resistance profiling, antimicrobial susceptibility and demographic characteristics of children with acute bacterial meningitis in a Southeastern tertiary health facility." International Journal of Scientific Reports 10, no. 11 (2024): 392–98. http://dx.doi.org/10.18203/issn.2454-2156.intjscirep20243051.

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Background: Over the years, varying patterns of bacterial susceptibility and multidrug resistance (MDR) rates have been reported in different settings. Detailed evaluation of the drug profile of the bacterial pathogens implicated in children with invasive bacterial infection helps to reduce the heightened risk of adverse events that could follow poorly managed or complicated cases in resource limited environment like ours. This study therefore, aimed to highlight the antibiotic susceptibility and MDR rate, and establish the relationship if any, between demographic characteristics and positive
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Dola, Nigha Zannat. "Microbial Profile in Paediatric Patients with Wound Infection and Their Antibiotic Susceptibility Pattern." Community Based Medical Journal 14, no. 1 (2025): 46–53. https://doi.org/10.3329/cbmj.v14i1.79299.

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Wound infection is one of the major health problems that frequently occur among patients reporting or admitted in the hospital. This observational study was conducted in the Department of Microbiology at Bangladesh Shishu Hospital and Institute, Dhaka, Bangladesh, between November 2023 and May 2024, to observe the microbial profile in paediatric patients with wound infection and their antibiotic susceptibility pattern. A total of 372 wound swabs were collected and analyzed by using culture and antibiotic sensitivity tests. From total wound swab samples, culture positive samples were 281(75.54%
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Nagaraj, S., BS Kalal, N. Kamath, and S. Muralidharan. "Microbiological and antimicrobial profile of pathogens associated with pediatric urinary tract infection: A one year retrospective study from a tertiary care teaching hospital." National Journal of Laboratory Medicine 3, no. 1 (2014): 4–7. https://doi.org/10.5281/zenodo.163563.

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Introduction: Urinary tract infections in the pediatric population are second only to respiratory tract infections. There is limited information on bacterial resistance to commonly used antibiotics or on the risk factors for increased resistance in these patients. Settings and Design: A retrospective study was carried out to evaluate the microbiological and antimicrobial profile of uropathogens isolated in between January 2011 and December 2011 from the pediatrics department, St John’s Medical College Hospital, a tertiary-care setting in Bangalore, India. Materials and Methods: Urine samples w
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