Academic literature on the topic 'Focal Seizures'

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Journal articles on the topic "Focal Seizures"

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Cascino, Gregory. "Midline Spikes Associated with Focal Epilepsy." Epilepsy Currents 2, no. 4 (2002): 116–18. http://dx.doi.org/10.1111/j.1535-7597.2002.t01-1-00044.x.

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Seizure Semiology and Neuroimaging Findings in Patients with Midline Spikes Kutluay E, Passaro EA, Gomez-Hassan D, Beydoun A Epilepsia 2001;42:1563–1568 Purpose Midline epileptiform discharges are rare compared with discharges at other scalp locations. Neuroimaging results and semiologic seizure characteristics of patients with midline spikes are not adequately described. The aim of this study was to describe the neuroimaging findings and detailed seizure semiologies in patients with midline spikes. Methods We reviewed the EEG database of the University of Michigan Medical Center and identifie
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Vinay, Kumar Shivaputrappa Appannavar, Chandrasekhar Gouli, Samruddhapoorn, and H. Udbal Durugappa. "To study clinical profile and correlation of EEG and CT findings in diagnosis of focal seizures in children at medical institution in mid – Karnataka region." World Journal of Advanced Research and Reviews 20, no. 1 (2023): 768–74. https://doi.org/10.5281/zenodo.12204106.

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Focal-onset seizures account for approximately 40% of seizures in children. Focal seizures are most commonly associated with underlying brain pathology in extreme age groups. Clinical correlation and localizing the site of the lesion play an important role in the early diagnosis and proper management of focal seizures in children. Objectives: To study the clinical profile and correlation of EEG and CT findings in children admitted to the paediatric ward of Medical College.A prospective study on the correlation of focal seizures, CT brain, and EEG studies was carried out in children in the age
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Ko, Young Jun, Il Han Yoo, Jiwon Lee, et al. "The Role of Focal Epilepsy Features in Defining <i>SCN1A</i> Mutation-positive Dravet Syndrome as Generalized and Focal Epilepsy." Journal of Epilepsy Research 11, no. 2 (2021): 127–35. http://dx.doi.org/10.14581/jer.21019.

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Background and Purpose: This study was aimed to describe focal epilepsy features of &lt;i&gt;SCN1A&lt;/i&gt; mutation-positive Dravet syndrome patients.Methods: A total of 82 &lt;i&gt;SCN1A&lt;/i&gt; mutation-positive patients were reviewed retrospectively (39 boys and 43 girls). Seizure type and electroencephalography (EEG) findings were investigated according to the stage, disease onset, and steady state (after age 2 years). Long-term video EEG data were used to classify the seizure type.Results: Focal seizures at onset and the steady state were found in 54.9% (45/82) and 90% (63/70) of pati
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International, Journal of Medical Science and Innovative Research (IJMSIR). "Tiny Tremors: A Case of Pediatric Focal Seizures Unraveled." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 4 (2024): 98–101. https://doi.org/10.5281/zenodo.15422389.

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<strong>Abstract</strong> <strong>Introduction</strong><strong>:</strong> Simple focal seizures, also known as auras, occur in one area on one side of the brain, but may spread from there (1). The person does not lose consciousness during a simple focal seizure. Physicians typically break simple focal seizures down into the following four areas, depending on the location in the brain and parts of the body affected: <strong>Motor</strong>: A simple focal seizure with motor symptoms will affect muscle activity, causing jerking movements of a foot, the face, an arm or another part of the body(2).
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Syed, Abdul Mohid, Y. Shasidhar Reddy, and Gangadhar B. Belavadi. "Study on etiology and clinical course of neonatal seizures and their outcome." International Journal of Contemporary Pediatrics 6, no. 5 (2019): 1985. http://dx.doi.org/10.18203/2349-3291.ijcp20193710.

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Background: The aim was to explore etiology, clinical course of neonatal seizure sand their and outcome in Narayana Medical College Hospital, Nellore, Andhra Pradesh, India.Methods: Retrospective study of 65 neonates from 1 month to 1 year diagnosed with epilepsy between November 2016 to August 2018.Results: Most common type of seizures seen are subtle (40%), followed by multifocalclonic (20%), tonic (21%), focal clonic (9.2%), clonic (7.7%) and myoclonic (1.6%). Most common cause of neonatal seizures was HIE (41.5%), followed by hypoglycemia (13.8%), intracranial bleed (10.8%), septicemia (10
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Carstairs, Claire, Anmol Pandey, Zachary Moulder, Monika Kosela, and Jeremy Rees. "Seizure Semiology Over Time in Adult Diffuse Glioma." Neuro-Oncology 24, Supplement_4 (2022): iv10. http://dx.doi.org/10.1093/neuonc/noac200.043.

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Abstract AIMS Patients with gliomas often present with generalised seizures, but subsequently develop focal seizures on treatment. The occurrence of a single generalised seizure at onset precludes the return of a driving licence, even if a patient continues to have only focal aware seizures. We investigated seizure semiology over time, to determine how many patients with ongoing seizures may be safe to drive. METHOD We analysed clinical data of patients with histologically-confirmed IDH-mutant diffuse gliomas, diagnosed between 2004-2015. Seizures were classified as: 1 – focal / 2 - generalise
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Fisher, Robert S. "Revised Operational Classification of Seizure Types." US Neurology 13, no. 02 (2017): 72. http://dx.doi.org/10.17925/usn.2017.13.02.72.

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The International League Against Epilepsy (ILAE) issued a revised operational classification of seizure types. The ILAE retained much of the old structure, but new features include new types of focal motor seizures: automatism, tonic, atonic, myoclonic, hyperkinetic, and spasm motor seizures. Focal nonmotor seizures can be autonomic, behavior arrest, cognitive, emotional, and sensory. A few new generalized types are included, as well as seizures of unknown onset. Partial is renamed focal. Simple partial is renamed focal aware and complex partial, focal impaired awareness. The new classificatio
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Chung, Steve S., Jacqueline A. French, Jacek Kowalski, et al. "Randomized phase 2 study of adjunctive cenobamate in patients with uncontrolled focal seizures." Neurology 94, no. 22 (2020): e2311-e2322. http://dx.doi.org/10.1212/wnl.0000000000009530.

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ObjectiveTo evaluate the efficacy and safety of adjunctive cenobamate 200 mg/d in patients with uncontrolled focal (partial-onset) seizures despite treatment with 1 to 3 antiepileptic drugs.MethodsIn this multicenter, double-blind, placebo-controlled study, adults 18 to 65 years of age with focal seizures were randomized 1:1 (cenobamate:placebo) after an 8-week baseline period. The 12-week double-blind treatment period consisted of a 6-week titration phase and a 6-week maintenance phase. The primary outcome was percent change in seizure frequency (from baseline) per 28 days during double-blind
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Volpe, Joseph J. "Neonatal Seizures: Current Concepts and Revised Classification." Pediatrics 84, no. 3 (1989): 422–28. http://dx.doi.org/10.1542/peds.84.3.422.

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In recent years, prolonged EEG monitoring with simultaneous observation by video recorder on by direct inspection has produced findings that suggest that (1) the number of certain neonatal seizures (when identified only clinically) has been overestimated in the past, and (2) the total number of neonatal seizures (identified electrographically but clinically silent) has been underestimated in the past. In this article, we propose a classification of seizures that includes the following as major seizure types: subtle, clonic, tonic, and myoclonic. Subtle seizure phenomena include those alteratio
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Shi, Yanfang, and Huancong Zuo. "Surgical treatment of focal inhibitory motor seizures." Journal of Neurosurgery: Pediatrics 9, no. 3 (2012): 301–4. http://dx.doi.org/10.3171/2011.12.peds11205.

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The authors describe a rare case of a pediatric patient with focal inhibitory motor seizures (ictal paralysis) with the seizure focus in the primary motor cortex. Seizures were characterized by ictal paralysis of the contralateral limbs without loss of consciousness. The seizure focus and progression were examined using long-term video electroencephalography (EEG) monitoring and MR imaging. Invasive recordings of the ictal EEG revealed spike rhythms arising from the primary motor cortex, suggesting that seizures associated with paralysis can arise from hyperactivity in either positive or negat
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Dissertations / Theses on the topic "Focal Seizures"

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McTague, Amy. "The molecular genetic investigation of epilepsy of infancy with migrating focal seizures." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10053215/.

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Epilepsy of infancy with migrating focal seizures (EIMFS) is characterised by the onset of frequent focal seizures in the first 6 months of life, a typical migratory EEG pattern and severe developmental delay. In this thesis, I report a cohort of patients with EIMFS, delineate clinical features and investigate the molecular genetic basis of this syndrome. In 2012, heterozygous mutations in the sodium-gated potassium channel KCNT1, were described in patients with EIMFS. Using a variety of genetic techniques, I have identified 12 patients with mutations in this gene. Four are novel, previously u
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Houston, Wes S. "PRESIDENTS TEST PERFORMANCE OF PATIENTS WITH FOCAL EPILEPSY." University of Cincinnati / OhioLINK, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=ucin991166083.

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Wang, Yujiang. "Multi-scale modelling of epileptic seizure rhythms as spatio-temporal patterns." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/multiscale-modelling-of-epileptic-seizure-rhythms-as-spatiotemporal-patterns(baad4a1e-fa22-47c2-84af-1c26b9399148).html.

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Epileptic seizures are characterised by an onset of abnormal brain activity that evolves in space and time, which ultimately returns to normal background activity. For different types of seizures, the abnormal activity can be vastly different both in duration, electrographic morphology and spatial extent. Mechanistic understanding of the different seizure dynamics (spatially, as well as temporally) is crucial for the advancement and improvement of clinical treatment. To gain a deeper mechanistic insight into different seizure dynamics, mathematical models of brain processes were developed in t
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Maynard, Lauren M. "Predictors of Epilepsy Severity in MRI-Identified Focal Cortical Dysplasia." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1458299543.

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Couturier, Nicholas H. "FIBER TRACT STIMULATION OF THE CORPUS CALLOSUM FOR FOCAL CORTICAL EPILEPSY." Case Western Reserve University School of Graduate Studies / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1572960613391293.

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BRESCHI, GIAN LUCA. "STUDIO ANATOMICO E FUNZIONALE DELLA REGIONE DI PENOMBRA IN UN MODELLO DI ISCHEMIA IN VITRO." Doctoral thesis, Università degli Studi di Milano, 2013. http://hdl.handle.net/2434/215236.

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ANATOMICAL AND FUNCTIONAL STUDY OF THE PENUMBRA REGION IN AN IN VITRO MODEL OF FOCAL CEREBRAL ISCHEMIA Experimental data have shown that the ischemic brain region is characterized by a highly damaged core surrounded by a rim of reversibly altered tissue, commonly referred to as the ischemic penumbra. The core region is characterized by a severely compromised CBF, whereas in the penumbra CBF is reduced but cellular metabolism is still preserved (Hossmann, 2008). One possible approach to identify core and penumbra is based on the evaluation of both metabolism and perfusion of the cerebral tis
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Jimenez, Jimenez Diego Mauricio. "Pathophysiology of seizure onset in human focal epilepsy and its relevance to epilepsy surgery." Thesis, King's College London (University of London), 2016. https://kclpure.kcl.ac.uk/portal/en/theses/pathophysiology-of-seizure-onset-in-human-focal-epilepsy-and-its-relevance-to-epilepsy-surgery(d062586c-22be-4351-84f2-0acc594c9460).html.

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Epilepsy is a major source of disability amongst all age groups. Most epilepsies are well controlled on antiepileptic drugs. However, significant proportions of patients are not controlled on medical treatment and may be successfully treated with resective surgery. Unfortunately, as many as 30% of patients remain with disabling seizures after resective surgery. In the present thesis I aim at identifying seizure onset patterns on intracranial EEG that are predictors of surgical outcome. Methods: I have studied all patients operated after intracranial recordings implantation between 1999 and 201
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Cho, Sukhee. "Astrocytic regulation of seizure-like behavior." eScholarship@UMMS, 2017. https://escholarship.umassmed.edu/gsbs_diss/959.

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Astrocytes are emerging as important regulators of neural circuit function and behavior in the healthy and diseased nervous system. In a screen for astrocyte molecules that modulate neuronal hyperexcitability we identified multiple components of focal adhesion complexes (FAs) as potent suppressors of genetically- or pharmacologically-induced seizure-like activity. Depletion of astrocytic Tensin, b-integrin, Talin, Focal adhesion kinase (FAK), or matrix metalloproteinase 1 (Mmp1), which degrades extracellular matrix to activate b-integrin receptors, resulted in enhanced recovery from, or resist
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Yee, Nicole. "Qualitative Assessment of Activated Microglia and Astrocytes in Focal Cortical Dysplasia: Case Series of Pediatric Patients." Thesis, The University of Arizona, 2017. http://hdl.handle.net/10150/623560.

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A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.<br>Epilepsy is the most common neurologic condition seen in children. Focal cortical dysplasia (FCD), a seizure disorder characterized by abnormal cortical laminar development, comprises approximately 75% of medically intractable epilepsies in the pediatric population. A greater appreciation of the pathology and intrinsic properties of the epileptogenic zone may help in understanding why FCD lesions are drug‐resistant, and could potentia
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NOBILI, PAOLA. "Seizure-induced pathologic plasticity and cell death in epileptogenic focal cortical dysplasia: converging evidences from human patients and an experimental model." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2014. http://hdl.handle.net/10281/52724.

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RATIONALE: We previously demonstrated in a rat model of chronic epilepsy associated with cortical malformations, the methylazoxymethanol (MAM)-pilocarpine -MP- rats, that status epilepticus (SE) and subsequent seizures set in motion a maladaptive plasticity altering the morphology of cortical pyramidal neurons and NMDA receptor expression and localization. We have here exploited the same model to verify i) the activation of cell death pathways in both neurons and glia during the course of epilepsy and ii) whether these changes could be related to epilepsy course. METHODS: MAM rats treated w
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Books on the topic "Focal Seizures"

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Liou, Jyun-you. The spatiotemporal dynamics of human focal seizures. [publisher not identified], 2017.

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Panayiotopoulos, C. P. Benign Childhood Focal Seizures and Related Epileptic Syndromes. Springer London, 2011. http://dx.doi.org/10.1007/978-1-84996-477-7.

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Bäumer, Dirk. Seizures. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0042.

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Seizures are transient neurological events caused by abnormal excessive or synchronous neuronal activity in the brain. This can arise from a localized brain region, causing focal seizures, or simultaneously from both hemispheres, leading to generalized seizures. Epilepsy is the tendency to develop recurrent seizures and is usually diagnosed after two or more unprovoked seizures. This chapter covers simple partial seizures (sometimes called aura), complex partial seizures, and focal (or partial) seizures, their differential diagnosis, context, approach to diagnosis, key diagnostic tests, therap
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Benign Childhood Focal Seizures And Related Epileptic Syndromes. Springer, 2010.

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Boro, Alex, and Jerome Engel. Clinical Presentation, Diagnosis, and Course: Epilepsy Syndromes with Focal Seizures. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0043.

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The epilepsies are a common and often devastating group of diseases characterized by recurrent seizures and coexisting conditions including cognitive, emotional, and behavioral comorbidities. These diseases affect about 1% of the population worldwide. About 60% of patients with epilepsy have focal seizures. The goal of this chapter is to describe the clinical presentation, epidemiology, and prognosis of the epilepsy syndromes characterized by focal seizures. The biological bases of these diseases and their management are explored in detail in other chapters in this volume.
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Mahta, Ali, and Peter B. Crino. Focal Cortical Dysplasias. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0039.

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Focal cortical dysplasias (FCDs) are common malformations of cerebral cortical development that are highly associated with medically intractable epilepsy. FCDs have been classified according to neuropathological subtypes (type Ia, Ib, IIA, IIb, and III) based on the severity of cytoarchitectural disruption, and the presence of unique cell types (e.g., balloon cells). Most FCDs can be detected by neuroimaging studies and will require respective epilepsy surgery to cure refractory seizures. The pathogenesis of FCDs remains to be defined, although current belief is that these lesions result from
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Kaplan, Tamara, and Tracey Milligan. Seizures and Epilepsy (DRAFT). Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190650261.003.0008.

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The video in this chapter explores seizures and epilepsy, including definitions or focal or generalized seizures and epilepsy, as well as the differences between the two. It discusses risk factors for epilepsy (family history, history of febrile seizures, brain injury) and its diagnosis (by history and EEG), as well as comorbidities of epilepsy (mood and cognitive disorders, accidents, and sudden unexpected death).
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Krishnan, Vaishnav, Bernard S. Chang, and Donald L. Schomer. The Application of EEG to Epilepsy in Adults and the Elderly. Edited by Donald L. Schomer and Fernando H. Lopes da Silva. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228484.003.0019.

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Surface or scalp electroencephalography (EEG) has become an indispensable tool for the diagnosis, classification, and care of patients with epilepsy across the age spectrum. This chapter provides an overview of interictal and corresponding ictal scalp EEG patterns observed in adults with certain classical epilepsy syndromes. In patients with one or more new-onset seizures, the value of EEG testing begins with a close examination of the interictal record. The morphology, frequency, and topography of interictal epileptiform discharges (when present) are typically sufficient to broadly distinguis
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Bertram, Edward H. Temporal Lobe Epilepsy. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0038.

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Temporal lobe epilepsy, as discussed in this chapter, is a focal epilepsy that involves primarily the limbic structures of the medial temporal lobe (amygdala, hippocampus, and entorhinal cortex). In recent years animal models have been developed that mirror the pathology and pathophysiology of this disease. This chapter reviews the human condition, the structural and physiological changes that support the development of seizures. The neural circuitry of seizure initiation will be reviewed with a goal of creating a framework for developing more effective treatments for this disease.
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Wijdicks, Eelco F. M., and Sarah L. Clark. Antiepileptic Drugs. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190684747.003.0006.

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Patients are often admitted to the neurosciences intensive care unit specifically for the treatment of a series of seizures or focal status epilepticus. Far more urgent is convulsive status epilepticus, which requires multiple intravenously administered antiepileptic drugs. The choices are different when the patient is in status epilepticus and refractoriness is mostly due to pharmacologic resistance. Use of an algorithm for decision making is common in the management of refractory status epilepticus. Antiepileptic drugs often interact with other antiepileptic drugs. This chapter discusses the
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Book chapters on the topic "Focal Seizures"

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Sperling, Michael R. "Focal Clonic Seizures." In Atlas of Epilepsies. Springer London, 2010. http://dx.doi.org/10.1007/978-1-84882-128-6_58.

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Jobst, Barbara C. "Focal Tonic Seizures." In Atlas of Epilepsies. Springer London, 2010. http://dx.doi.org/10.1007/978-1-84882-128-6_59.

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Skidmore, Christopher T. "Focal Myoclonic Seizures." In Atlas of Epilepsies. Springer London, 2010. http://dx.doi.org/10.1007/978-1-84882-128-6_60.

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Jobst, Barbara C. "Focal Hyperkinetic Seizures." In Atlas of Epilepsies. Springer London, 2010. http://dx.doi.org/10.1007/978-1-84882-128-6_61.

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Skidmore, Christopher T. "Focal Inhibitory Seizures." In Atlas of Epilepsies. Springer London, 2010. http://dx.doi.org/10.1007/978-1-84882-128-6_62.

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Zangaladze, Andro. "Focal Somatosensory Seizures." In Atlas of Epilepsies. Springer London, 2010. http://dx.doi.org/10.1007/978-1-84882-128-6_63.

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Stern, John M. "Focal Vertiginous Seizures." In Atlas of Epilepsies. Springer London, 2010. http://dx.doi.org/10.1007/978-1-84882-128-6_68.

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Urbach, Horst, and Jörg Wellmer. "Localization of Focal Seizures." In MRI in Epilepsy. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/174_2012_554.

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Nickels, Katherine. "Focal Seizures in Children." In Epilepsy Case Studies. Springer International Publishing, 2013. http://dx.doi.org/10.1007/978-3-319-01366-4_8.

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Caraballo, Roberto H., Giuseppe Capovilla, and Antonino Romeo. "Benign Focal Seizures of Adolescence." In Atlas of Epilepsies. Springer London, 2010. http://dx.doi.org/10.1007/978-1-84882-128-6_145.

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Conference papers on the topic "Focal Seizures"

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Diao, Yueqin, Jiansheng Fang, Yan Ding, Ying Zhao, Heng Meng, and Yanwu Xu. "Temporal-Focal Attention on EEG for Cross-Patient Epileptic Seizure Detection." In 2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI). IEEE, 2025. https://doi.org/10.1109/isbi60581.2025.10980801.

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Sadoun, Maria Sara Nour, and Taous-Meriem Laleg-Kirati. "Seizure Onset Zone Localization in Focal Epilepsy using stereo-EEG: SCSA and Visibility Graph complementary features." In 2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2024. https://doi.org/10.1109/embc53108.2024.10782524.

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Hartigan, Thomas, Lauren Byrne, Sarah Lavelle, Ali McDonnell, Kieron Sweeney, and Richard B. Reilly. "An Improved Neurosurgical Planning Method for Focal Epileptic Seizure Surgery using Stereo-EEG-Based Source Localization and Multimodal Imaging." In 2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2024. https://doi.org/10.1109/embc53108.2024.10781654.

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Chen, Yue, Megan E. Poorman, David B. Comber, et al. "Treating Epilepsy via Thermal Ablation: Initial Experiments With an MRI-Guided Concentric Tube Robot." In 2017 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dmd2017-3408.

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Epilepsy is a prevalent neurological disorder affecting 65 million people globally [1]. Anti-epileptic medications fail to provide effective seizure control for 30% of patients, placing them at a 7–17% risk of Sudden Unexplained Death in Epilepsy and recurrent seizures. Surgical resection of the seizure focus is a potentially curative treatment for patients with seizures that electrophysiologically correlate to a focal lesion. For these patients, focal surgical resection can result in 60–70% seizure-freedom rates [2]. However, open resection carries the risk of cognitive impairment or focal ne
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Khouaja, Ibtissem, Imane Youkana, and M. Ali Saafi. "Monitoring Consciousness and Spatiotemporal Dynamics During Complex Focal Seizures." In 2020 5th International Conference on Advanced Technologies for Signal and Image Processing (ATSIP). IEEE, 2020. http://dx.doi.org/10.1109/atsip49331.2020.9231891.

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Falcicchio, Giovanni, and Michiel Tent. "Real-world efficacy of cenobamate in focal-onset seizures." In EAN 2022 Congress, edited by Giovanni Falcicchio and Hans-Peter Hartung. Medicom Medical Publishers, 2022. http://dx.doi.org/10.55788/1546ab9d.

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Hata, Kei, Koichi Fujiwara, Manabu Kano, et al. "Design of focal brain cooling system for suppressing epileptic seizures." In 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2017. http://dx.doi.org/10.1109/embc.2017.8036817.

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Morais, Gabriela Lopes de, Ellen Silva de Carvalho, Anny Karoliny de Santana Nogueira, et al. "Elderly man presenting with focal seizures, encephalopathy and tumefactive lesion on imaging scans." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.753.

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An 84-year-old man with cardiomyopathy and a pacemaker was admitted to our hospital due to a focal impaired awareness seizure. Computed tomography (CT) scan on admittance evidenced right parieto-occipital hypodensity with mild mass effect. A non-contrast CT scan realized in an outer institution seven months earlier showed that such hypodensity, considered then as a stroke, was present, but slowly progressing. He was submitted to therapy with phenytoin upon entry and his electroencephalogram showed increased slow-wave activity. Cerebrospinal fluid showed hyperproteinrachia, normal cell count an
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Silveira, Rayanne Maria Brandão da, Marcela Marques de Oliveira Gregório, Elza Marcia Targar Yacubian, and Laura Maria de Figueiredo Ferreira Guilhoto. "Cardiovascular risk in adults with drug-resistant epilepsy submitted to the modified atkins diet." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.728.

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Introduction: The modified Atkins diet (MAD) the carbohydrates are limited to 15–30 g/d and high fat intake is encouraged. It are used in children, being less studied in adults Objectives: To assess the impact of MAD over a 6-month period in adults with drug-resistant epilepsy in terms of reduction in seizure frequency and cardiovascular risk. Methods: Prospective and interventional study.Inclusion criteria:patients aged 18–60 yrs, with drug-resistant focal epilepsy, without surgical indication or in the postoperative of epilepsy surgery. Exclusion criteria were: use of corticosteroids, metabo
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Chung, Steve, Samy Guirguis, David Cantu, et al. "Efficacy, Safety, and Tolerability of Adjunctive Eslicarbazepine Acetate in Focal Seizure Patients With Focal to Bilateral Tonic-Clonic Seizures at Baseline (P14-1.003)." In 2023 Annual Meeting Abstracts. Lippincott Williams & Wilkins, 2023. http://dx.doi.org/10.1212/wnl.0000000000202263.

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Reports on the topic "Focal Seizures"

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Treadwell, Jonathan R., Mingche Wu, and Amy Y. Tsou. Management of Infantile Epilepsies. Agency for Healthcare Research and Quality (AHRQ), 2022. http://dx.doi.org/10.23970/ahrqepccer252.

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Objectives. Uncontrolled seizures in children 1 to 36 months old have serious short-term health risks and may be associated with substantial developmental, behavioral, and psychological impairments. We evaluated the effectiveness, comparative effectiveness, and harms of pharmacologic, dietary, surgical, neuromodulation, and gene therapy treatments for infantile epilepsies. Data sources. We searched Embase®, MEDLINE®, PubMed®, the Cochrane Library, and gray literature for studies published from January 1, 1999, to August 19, 2021. Review methods. Using standard Evidence-based Practice Center me
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