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1

Iacono, G., A. Carroccio, F. Cavataio, G. Montalto, M. Soresi, and V. Balsamo. "Use of Ass' Milk in Multiple Food Allergy." Journal of Pediatric Gastroenterology and Nutrition 14, no. 2 (1992): 177–81. http://dx.doi.org/10.1002/j.1536-4801.1992.tb10521.x.

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SummaryWe report a study of realimentation techniques in 9 unweaned infants with multiple food hypersensitivity. The patients had presented severe symptoms of cow's milk allergy and successive attempts using milk containing soy protein and/or a semielemental formula in their alimentation did not improve their clinical condition, due to the onset of hypersensitivity to these allergens as well. After a short period of parenteral alimentation the infants were refed per os with ass' milk (250 ml/kg/day) + medium chain triglycerides (40 ml/L milk). This food was well tolerated by all patients. No n
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2

AlSaimary, Ihsan E., and Falih Hmood Mezban. "Diagnostic Accuracy of Immunological Markers for Detection of Allergens by Poly Check Techniques among Patients with Bronchial Asthma in Basrah, Southren of Iraq." Journal of Biotechnology & Bioinformatics Research 3, no. 1 (2021): 1–16. http://dx.doi.org/10.47363/jbbr/2021(3)125.

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This study aimed to estimate specific IgE by poly check technique against various allergens. In the present study 56 environmental allergens (food, fungal, agricultural, and aeroallergens) were tested against specific IgE. This study found a very high significant allergen – specific IgE reactions with a high degrees mediated a various forms of hypersensitivity is sever in 4 and 5 stage of age groups to males asthma patients, in allergens except Cat Ep. While in females recorded severe hypersensitivity in 2, 3 and 4 stage of age groups, in allergens except cat. Ep., Plantain, hazel pollen. And
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3

Mgonja, Frida Richard, and Kaswija John Paul. "Antibiotic Residues in Foods of Animal Origin: Review." Journal of Biology and Life Science 14, no. 1 (2023): 65. http://dx.doi.org/10.5296/jbls.v14i1.20659.

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Antibiotic residue in food is a serious public health issue that demands much attention and has a harmful impact on consumer health. The presence of antibiotic residue in food of animal origin creates challenges in global trade in animals and animal products. Public health implications of antibiotic residue in food include the development and propagation of antimicrobial drug resistance, hypersensitivity reactions, carcinogenicity, mutagenicity, teratogenicity, bone marrow suppression, and disruption of normal intestinal flora. Improper use of antibiotics in animals results in the existence of
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4

Ullah, Hammad, Yaseen Hussain, Cristina Santarcangelo, et al. "Natural Polyphenols for the Preservation of Meat and Dairy Products." Molecules 27, no. 6 (2022): 1906. http://dx.doi.org/10.3390/molecules27061906.

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Food spoilage makes foods undesirable and unacceptable for human use. The preservation of food is essential for human survival, and different techniques were initially used to limit the growth of spoiling microbes, e.g., drying, heating, salting, or fermentation. Water activity, temperature, redox potential, preservatives, and competitive microorganisms are the most important approaches used in the preservation of food products. Preservative agents are generally classified into antimicrobial, antioxidant, and anti-browning agents. On the other hand, artificial preservatives (sorbate, sulfite,
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5

Sharma, Yatharth, Prasad Patil, Manjit M. Khatal, et al. "Biological and Chemical Factors Influencing Food Allergies: A Comprehensive Review." Journal of Scientific Research and Reports 30, no. 6 (2024): 787–94. http://dx.doi.org/10.9734/jsrr/2024/v30i62095.

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Food allergies have become a significant public health concern, affecting millions worldwide. This comprehensive review explores the multifaceted nature of food allergies, shedding light on the intricate interplay of biological and chemical factors. We delve into the mechanisms of allergen recognition and sensitization, genetic predisposition, and the role of the gut microbiome. Moreover, we examine the influence of food processing techniques, additives, and cross-reactivity in the development and severity of food allergies. Food allergies, an adverse health condition triggered by the immune s
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6

Khalifa, Hazim O., Lamek Shikoray, Mohamed-Yousif Ibrahim Mohamed, Ihab Habib, and Tetsuya Matsumoto. "Veterinary Drug Residues in the Food Chain as an Emerging Public Health Threat: Sources, Analytical Methods, Health Impacts, and Preventive Measures." Foods 13, no. 11 (2024): 1629. http://dx.doi.org/10.3390/foods13111629.

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Veterinary medications are necessary for both contemporary animal husbandry and food production, but their residues can linger in foods obtained from animals and pose a dangerous human risk. In this review, we aim to highlight the sources, occurrence, human exposure pathways, and human health effects of drug residues in food-animal products. Following the usage of veterinary medications, pharmacologically active compounds known as drug residues can be found in food, the environment, or animals. They can cause major health concerns to people, including antibiotic resistance development, the dev
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7

Singh, Neha, and Khushboo Bhange. "Environmental fungal spore aerosolization: a review." Journal of Bacteriology & Mycology: Open Access 11, no. 1 (2023): 20–22. http://dx.doi.org/10.15406/jbmoa.2023.11.00338.

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Bioaerosol containing fungal spores became public health hazards. The aerosols contain the fungal spores of different species of Aspergillus, Cladosporium, Chaetomium, Penicillium, Wallemia, Stachybotrys etc. and caused various life-threatening respiratory diseases such as hypersensitivity, pneumonia, Aspergillosis, Candidiasis, Mucormycosis, Cancer, etc. They are easily transmitted from one individual to another. They also cause extreme damage to crops and create problems in food security by producing mycotoxins. The transmissions of fungal spores depend upon the environmental factor, seasona
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8

Corey, Jacquelynne P., and Anil Gungor. "In vitro testing for immunoglobulin E-mediated food allergies." Otolaryngology–Head and Neck Surgery 115, no. 4 (1996): 312–18. http://dx.doi.org/10.1016/s0194-5998(96)70044-x.

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The role of immunoglobulin E-mediated food allergy in subjects with allergic disorders, especially in patients with rhinitis and sinusitis, is underestimated by clinicians because of the initial attribution of these disorders to immediate-type hypersensitivity reactions. The difficulties of diagnosing food-related reactions have caused further delay in their recognition and incorporation into the daily practice of diagnosing food allergy. Two of the diagnostic methods for food allergy are the in vitro assay of total immunoglobulin E and the measurement of food-specific immunoglobulin E levels
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9

Punj, Anahita, Sanjay Vasudevan, P. Ajay Reddy, and Abhinav Atchuta. "Interdisciplinary Triumph: Molar Preservation through the Unity of Periodontology, Prosthodontics, and Endodontics." Journal of Interdisciplinary Dentistry 14, no. 2 (2024): 136–39. http://dx.doi.org/10.4103/jid.jid_27_24.

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Preserving teeth is a long-term goal for each specialty of dentistry. Many times, it involves the use of interdisciplinary work and team effort to reach the desired goal. With the advancement of age and patient education, many patients have the desire to save their teeth as long as possible. Incorrect brushing techniques can lead to gingival recession, which, over a period of time, can advance to severe attachment loss of periodontal structures, causing complete denudation of the tooth root. Ultimately, it results in dentinal hypersensitivity and, consequently, chronic pulpitis. Over a period
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10

Nunes, João C. F., Raquel O. Cristóvão, Mara G. Freire, et al. "Recent Strategies and Applications for l-Asparaginase Confinement." Molecules 25, no. 24 (2020): 5827. http://dx.doi.org/10.3390/molecules25245827.

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l-asparaginase (ASNase, EC 3.5.1.1) is an aminohydrolase enzyme with important uses in the therapeutic/pharmaceutical and food industries. Its main applications are as an anticancer drug, mostly for acute lymphoblastic leukaemia (ALL) treatment, and in acrylamide reduction when starch-rich foods are cooked at temperatures above 100 °C. Its use as a biosensor for asparagine in both industries has also been reported. However, there are certain challenges associated with ASNase applications. Depending on the ASNase source, the major challenges of its pharmaceutical application are the hypersensit
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11

Habib, Rahat Bin, and ARM Luthful Kabir. "The Risks of Forceful Feeding: Lentil Soup Aspiration and Its Association to Hypersensitivity Pneumonitis (HP) in Weaning Young Children." Journal of Ad-din Women's Medical College 13, no. 1 (2025): 31–36. https://doi.org/10.3329/jawmc.v13i1.81327.

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Forceful feeding practices, especially during the weaning period, are prevalent in South Asian countries, such as Bangladesh, where lentil soup is commonly introduced to young children. However, this practice can lead to accidental aspiration of food, resulting in hypersensitivity pneumonitis (HP), an immune-mediated inflammatory lung disease. This article explores the association between lentil soup aspiration due to forceful feeding and HP in pediatric patients. The pathophysiology of HP involves immune complex-mediated (Type III) and delayed-type hypersensitivity (Type IV) reactions, trigge
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12

Cekova-Yaneva, Mariana, Iliyana Stoeva-Ivanova, and Georgi S. Nikolov. "DEVELOPING AN INDIVIDUALIZED TREATMENT PLAN FOR DENTAL PATIENTS WITH ACCOMPANYING SENSITIZATION TO BACTERIA, FOOD, POLLEN, AND MORE." Journal of IMAB - Annual Proceeding (Scientific Papers) 26, no. 4 (2020): 3378–82. http://dx.doi.org/10.5272/jimab.2020264.3378.

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Contemporary dental medicine offers a wide range of materials and techniques for the rehabilitation of the dentomaxillofacial system, which in recent years has led to a dramatic increase in allergic reactions in sensitized patients after dental treatment. Once in the oral cavity, saliva and gastrointestinal tract, dental medication or dental material release products that, under certain conditions, can cause direct cell damage or induce an immunological/allergic reaction. The local and systemic reactivity in each individual is different and this explains why biocompatible materials that persis
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13

Iannaccone, Marco, Gianfranco Cosenza, Alfredo Pauciullo, et al. "Milk microRNA-146a as a potential biomarker in bovine tuberculosis." Journal of Dairy Research 85, no. 2 (2018): 178–80. http://dx.doi.org/10.1017/s0022029918000122.

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In this research communication we exploited the potential use of milk microRNAs (miRs) as biomarkers for bovine tuberculosis (bTB). bTB is a zoonotic disease caused by Mycobacterium bovis which affects animal health, influencing herd economic sustainability. Diagnosis is based on skin delayed-type hypersensitivity reaction and quantification of interferon gamma but both techniques are influenced by several confounding factors. Thus, new methods for early diagnosis are required. In this context, microRNAs have been used as promising biomarkers for both infectious and non-infectious diseases. To
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14

Rodrigues, Helena, Marta Leite, Beatriz Oliveira, and Andreia Freitas. "Antibiotics in honey: a comprehensive review on occurrence and analytical methodologies." Open Research Europe 4 (November 8, 2024): 125. http://dx.doi.org/10.12688/openreseurope.17664.2.

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Honey is a food of great nutritional importance and has always been used for human consumption. The production of honey and other beekeeping products depends on the proper functioning of this extremely important sector, as it has a direct impact on other sectors such as agriculture. The decline in bee colony numbers has been linked, among other factors, to bacterial diseases affecting bees, including American and European foulbrood, and Nosema spp. disease. In this matter, prophylactic or therapeutic use of veterinary drugs in apiculture is common but can lead to their accumulation in bees and
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15

Quinn, A. G., J. McLelland, T. Essex, and P. M. Farr. "Quantification of contact allergic inflammation: a comparison of existing methods with a scanning laser Doppler velocimeter." Acta Dermato-Venereologica 73, no. 1 (1993): 21–25. http://dx.doi.org/10.2340/00015555732125.

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Responses to a range of doses of common contact dermatitis/producing allergens were measured using a novel scanning laser Doppler velocimeter and three commonly used conventional measurement techniques. The techniques were compared in terms of sensitivity, measurement error, range of the linear portion of the dose/response curve and ease of use. The detection thresholds of the objective methods did not differ significantly and did not detect responses at concentrations less than those required to produce a visible response. Of the objective methods the range of linearity was greatest when reac
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16

Reyes, Niel Khangel S. "Hypopharyngeal, Supraglottic and Subglottic Stenosis after 1 Week Intubation." Philippine Journal of Otolaryngology-Head and Neck Surgery 30, no. 2 (2015): 62–64. http://dx.doi.org/10.32412/pjohns.v30i2.361.

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Laryngeal stenosis is a partial or complete narrowing of the endolarynx and has many etiologies. Common causes of laryngeal stenosis are iatrogenic (prolonged intubation, laryngeal surgery), external neck trauma, congenital, burns, ingestions, infection, and inflammation (gastroesophageal reflux or Wegener’s). Laryngeal stenosis secondary to trauma usually affects the posterior endolaryngeal region in adults and the subglottic region in children.1
 Patients with mild to moderate laryngeal stenosis are usually asymptomatic and if otherwise, majority of the presenting signs and symptoms are
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17

Hartman, Amy, Deniz Kocanaogullari, Adriane Soehner, Roxanna Bendixen, and Murat Akcakaya. "0760 Applying machine learning to examine settling down period for children with and without sensory hypersensitivities." SLEEP 46, Supplement_1 (2023): A335—A336. http://dx.doi.org/10.1093/sleep/zsad077.0760.

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Abstract Introduction Children with sensory hypersensitivities have poorer subjective sleep health than their peers. However, traditional actigraphy variables (e.g., sleep efficiency, sleep duration) do not adequately capture these sleep deficits. In qualitative interviews, caregivers of children with sensory hypersensitivities identified the settling down period prior to sleep as a major family stressor, potentially indicating a novel target for intervention. We applied machine learning techniques to thoroughly characterize and discriminate differences in the settling down period for children
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18

Kozera, Katarzyna, Bogdan Ciszek, and Paweł Szaro. "Posterior Branches of Lumbar Spinal Nerves – Part III: Spinal Dorsal Ramus Mediated Back Pain – Pathomechanism, Symptomatology and Diagnostic Work-up." Ortopedia Traumatologia Rehabilitacja 19, no. 4 (2017): 0. http://dx.doi.org/10.5604/01.3001.0010.4611.

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Spinal Dorsal Ramus Mediated Back Pain is the second most frequently described condition (the first one being Lumbar Facet Syndrome) originating from pathology involving posterior branches of lumbar spinal nerves. Spinal Dorsal Ramus Mediated Back Pain was described as “thoracolumbar junction syndrome” by Maigne in 1989. As a rule, Spinal Dorsal Ramus Mediated Back Pain presents unilaterally within posterior branches at the levels Th11-12 and L1-2. The pain is triggered by extension and/or rotation. Typical symptoms include pain that may radiate towards the gluteal area and posterior iliac cre
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19

Iheukwumere, C. M., I. H. Iheukwumere, U. O. Okoli, and C. H. Ugwu. "Immunological Impact of Fermented Soybean Condiments Produced from Indigenous Fermenters." Journal of Advances in Microbiology 23, no. 10 (2023): 27–37. http://dx.doi.org/10.9734/jamb/2023/v23i10754.

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Several studies have shown that most condiments consumed in Nigeria today are fortified with chemicals that alter the nature and stripped the natural immunological adjuvants designed by nature to protect the body system. Several condiments have been developed from fermented foods in order to control this ugly situation but there is still controversial thought in the choice of microorganism to be used in order to produce a non-toxic condiment with an improved immunological function. The aim of this study was to evaluate the toxicity, nutritive value and immunological impact of fermented soybean
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20

Shanaj Parvin, Most, and Md Ehsanul Haque. "Microrna Regulation of Nodule Zone-Specific Gene Expression In Soybean." Journal of Natural Products and Natural Products Synthesis 1, no. 1 (2021): 15–21. http://dx.doi.org/10.55124/jnns.v1i1.82.

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Nitrogen is a paramount important essential element for all living organisms. It has been found to bea crucial structural component of proteins, nucleic acids, enzymes and other cellular constituents which are inevitable for all forms of life. In the atmosphere, the percentage of nitrogen is very high (N2, 78%) compared to other inorganic gases. However, most organisms have practically no direct access to this nitrogen. While plants can not directly uptake nitrogen from atmosphere, they are capable of assimilating other forms of nitrogen, for example ammonium (NH4+) and nitrate (NO3-). For agr
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21

Mustafa, Yasser Fakri, Gholamabbas Chehardoli, Sepideh Habibzadeh, and Zeinab Arzehgar. "Electrochemical detection of sulfite in food samples." Journal of Electrochemical Science and Engineering, November 29, 2022. http://dx.doi.org/10.5599/jese.1555.

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In various pharmaceutical and food industries, sulfite is utilized for the inhibition of nonenzymatic and enzymatic browning. Also, in brewing industries, it acts as an antioxidizing and antibacterial agent. Several toxic and adverse reactions, including vitamin deficiency, hypersensitivity, and allergic diseases, have been attributed to sulfite ingestion that may cause dysbiotic oral and gut microbiota events. Thus, the content of sulfite in foods must be controlled and monitored, and it is essential to find a specific, reproducible, and sensitive method to detect sulfite. Some analytical sol
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22

Zhao, Jinlong, Mukeshimana Camus‐Ela, Lili Zhang, et al. "A comprehensive review on mango allergy: Clinical relevance, causative allergens, cross‐reactivity, influence of processing techniques, and management strategies." Comprehensive Reviews in Food Science and Food Safety 23, no. 2 (2024). http://dx.doi.org/10.1111/1541-4337.13304.

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AbstractMangoes (Mangifera indica) are widely prized for their abundant nutritional content and variety of beneficial bioactive compounds and are popularly utilized in various foods, pharmaceuticals, and cosmetics industries. However, it is important to note that certain proteins present in mango can trigger various allergic reactions, ranging from mild oral allergy syndrome to severe life‐threatening anaphylaxis. The immunoglobulin E‐mediated hypersensitivity of mango is mainly associated with three major allergenic proteins: Man i 1 (class IV chitinase), Man i 2 (pathogenesis‐related‐10 prot
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23

Jiang, Lianghong, Fen Xu, Weiwei Feng, Chen Fu, and Changjiang Zhou. "The value of hypersensitivity quantitative fecal immunochemical test in early colorectal cancer detection." Postgraduate Medical Journal, December 6, 2023. http://dx.doi.org/10.1093/postmj/qgad114.

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Abstract At present, both the incidence and mortality rates of colorectal cancer are on the rise, making early screening a crucial tool in reducing the fatality rate. Although colonoscopy is the recommended method according to the guidelines, compliance tends to be poor. The fecal immunochemical test (FIT), a new technology that uses latex immunoturbidimetry to detect fecal blood, offers high specificity and sensitivity. Additionally, it is low-cost, easy to operate, and less likely to be affected by food and drugs, thus improving the compliance rate for population screening. Compared to other
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24

Nayab, Tayyaba, Ammara Chaudhry, Muhammad Saad Shaikh, Sana Ikram, Nimra Meraj, and Rabia Ijaz. "Evaluating Patient Experiences and Perceptions in the Diagnosis and Management of Dentine Hypersensitivity: A Cross-Sectional Study." Pakistan Journal of Health Sciences, November 30, 2024, 203–8. https://doi.org/10.54393/pjhs.v5i11.2055.

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Dentine Hypersensitivity (DH), or sensitive teeth, was a dental pain caused by exposure of dentinal tubules. Understanding patients' experiences and perceptions was crucial for developing effective diagnostic and treatment plans. Objective: To investigate the patients' experiences, perceptions, and diagnostic techniques for DH. The research also addresses the therapy approaches to limit dentine hypersensitivity for the better quality of life in patients. Methods: A non-probability convenience sampling technique was used to conduct the study for three months, from April 2024 to June 2024, in th
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25

Tontini, Chiara, Urszula Radzikowska, Carlos J. Aranda, et al. "The Use of Omics Sciences in Allergic Diseases From Bench to Bedside: An EAACI Position Paper." Allergy, July 2, 2025. https://doi.org/10.1111/all.16638.

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ABSTRACTOmics have revolutionized our understanding of allergic diseases, with increasingly more studies adopting techniques like genomics, proteomics, and metabolomics over the years. Integrating high‐dimensional omics data with clinical features can enable more precise disease classification and biomarker identification, leading to improved disease management and the development of novel therapies. However, translating these discoveries into clinical practice remains a challenge. In this European Academy of Allergy and Clinical Immunology (EAACI) Position Paper, the Task Force (TF) “The Use
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26

Singh, Meghan, Gokul Sridharan, Dhanraj Ganapathy, and Ashok K. Sundramoorthy. "Electrochemical Detection of Gallic Acid Using Zinc Oxide/Graphene Oxide Hybrid Nanocomposite-modified Electrode." Nanoscience & Nanotechnology-Asia 15 (March 21, 2025). https://doi.org/10.2174/0122106812375545250313081034.

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Background: Gallic acid (GA) is an important biomarker with significant relevance in the food, pharmaceutical, and environmental industries, requiring highly sensitive and selective detection techniques. Aim: This study presents the development of a robust electrochemical sensor for GA detection, utilizing a zinc oxide/graphene oxide (ZnO/GO) nanocomposite-modified electrode, with a focus on applications for assessing the impact of GA on oral health. Methods: GO was synthesized via a modified Hummers' method, while ZnO nanoparticles with rodshaped morphology were prepared hydrothermally. The Z
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27

Cohen, Matthew, Asma Fikree, and Calum D. Moulton. "Using central gut–brain neuromodulators to manage disorders of gut–brain interaction: a practical guide for gastroenterologists." Frontline Gastroenterology, June 6, 2025, flgastro—2024–103007. https://doi.org/10.1136/flgastro-2024-103007.

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Disorders of gut–brain interaction (DGBI) are common clinical presentations in gastroenterology. Central gut–brain neuromodulator medications have an increasingly important role in the management of DGBI. However, gastroenterologists often lack confidence in prescribing central neuromodulators and typically lack access to specialist psychiatric support. This review aims to provide a practical guide to the prescribing of key central neuromodulator medications. We first suggest a positive dialogue for discussing DGBI, covering concepts such as visceral hypersensitivity, central sensitisation and
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28

Rodrigues, Helena, Marta Leite, Beatriz Oliveira, and Andreia Freitas. "Antibiotics in honey: a comprehensive review on occurrence and analytical methodologies." Open Research Europe, June 24, 2024. https://doi.org/10.12688/openreseurope.17664.1.

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Honey is a food of great nutritional importance and has always been used for human consumption. The production of honey and other beekeeping products depends on the proper functioning of this extremely important sector, as it has a direct impact on other sectors such as agriculture. The decline in bee colony numbers has been linked, among other factors, to bacterial diseases affecting bees, including American and European foulbrood, and Nosema spp. disease. In this matter, prophylactic or therapeutic use of veterinary drugs in apiculture is common but can lead to their accumulation in bees and
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29

Rodrigues, Helena, Marta Leite, Beatriz Oliveira, and Andreia Freitas. "Antibiotics in honey: a comprehensive review on occurrence and analytical methodologies." Open Research Europe, November 8, 2024. https://doi.org/10.12688/openreseurope.17664.2.

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Honey is a food of great nutritional importance and has always been used for human consumption. The production of honey and other beekeeping products depends on the proper functioning of this extremely important sector, as it has a direct impact on other sectors such as agriculture. The decline in bee colony numbers has been linked, among other factors, to bacterial diseases affecting bees, including American and European foulbrood, and Nosema spp. disease. In this matter, prophylactic or therapeutic use of veterinary drugs in apiculture is common but can lead to their accumulation in bees and
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30

Jafari, Nazanin, Mina Seyed Habashi, Alireza Hashemi, Reza Shirazi, Nader Tanideh, and Amin Tamadon. "Application of bioactive glasses in various dental fields." Biomaterials Research 26, no. 1 (2022). http://dx.doi.org/10.1186/s40824-022-00274-6.

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AbstractBioactive glasses are a group of bioceramic materials that have extensive clinical applications. Their properties such as high biocompatibility, antimicrobial features, and bioactivity in the internal environment of the body have made them useful biomaterials in various fields of medicine and dentistry. There is a great variation in the main composition of these glasses and some of them whose medical usage has been approved by the US Food and Drug Administration (FDA) are called Bioglass. Bioactive glasses have appropriate biocompatibility with the body and they are similar to bone hyd
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31

Borrelli, Michela, Tasha Nasrollahi, Jonathan Raskin, Sana Khan, and Omid B. Mehdizadeh. "Severe Airway Edema Following Calcium Hydroxylapatite (CaHA) Injection Augmentation." Ear, Nose & Throat Journal, September 29, 2022, 014556132211275. http://dx.doi.org/10.1177/01455613221127584.

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This case study presents an abnormal complication after routine injection augmentation using calcium hydroxylapatite (CaHA) vocal fold filler in-office on a 73-year-old female. The patient presented initially with severe dysphonia, hypophonia, and a past surgical history of total thyroidectomy, bilateral neck dissection, and a right lateral neck dissection for history of metastatic papillary thyroid carcinoma. She also had a past medical history of hypothyroidism. Post-injection of CaHA, the patient developed severe laryngeal edema, limited vocal cord mobility, obliteration of the pyriform, an
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32

Nagarajappa, Ramesh, Priyanca Panigrahi, Dharmashree Satyarup, et al. "Comparison of Vantej and Dente 91 Toothpastes in the Management of Dentin Hypersensitivity: A Randomised Clinical Trial." JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2023. http://dx.doi.org/10.7860/jcdr/2023/64972.18532.

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Introduction: Dentinal hypersensitivity is a prevalent and distressing dental condition characterised by acute, transient pain or discomfort arising from exposed dentin in response to external stimuli, such as variations in temperature, mechanical stimuli, or consumption of acidic or sweet foods. Dentinal Hypersensitivity (DH) impacts daily activities, such as eating, drinking, and oral hygiene practices. Dentifrices are commonly used in the treatment of hypersensitivity, as they relieve sensitivity by obstructing nerve pathways through the formation of compounds. Aim: The aim of the study is
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33

Copaescu, Ana, Phuti Choshi, Sarah Pedretti, Effie Mouhtouris, Jonathan Peter, and Jason A. Trubiano. "Dose Dependent Antimicrobial Cellular Cytotoxicity—Implications for ex vivo Diagnostics." Frontiers in Pharmacology 12 (August 10, 2021). http://dx.doi.org/10.3389/fphar.2021.640012.

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Introduction:Ex vivo and in vitro diagnostics, such as interferon-γ (IFN-γ) release enzyme linked ImmunoSpot (ELISpot) and flow cytometry, are increasingly employed in the research and diagnostic setting for severe T-cell mediated hypersensitivity. Despite an increasing use of IFN-γ release ELISpot for drug causality assessment and utilization of a range of antimicrobial concentrations ex vivo, data regarding antimicrobial-associated cellular cytotoxicity and implications for assay performance remain scarcely described in the literature. Using the measurement of lactate dehydrogenase (LDH) and
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