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1

Malkin-Washeim, Diana Louise. "Electronic Benefit Transfer: Food Choices, Food Insecurity, and Type 2 Diabetes." ScholarWorks, 2015. http://scholarworks.waldenu.edu/dissertations/1318.

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The purpose of this research was to examine food security for people with prediabetes participating in the Supplemental Nutrition Assistance Program (SNAP), focusing on their food choice decisions and coping strategies over a 30-day benefit cycle that potentially increases the risk of Type 2 diabetes. A cross-sectional, quantitative design based on food choice process model constructs was used. SNAP participants (n = 36) with prediabetes, aged 21â??70 years, were recruited as outpatients from Bronx Lebanon Hospital and completed self-reported questionnaires on demographics and health, food security, and food frequency. Descriptive statistics, Pearson chi square tests, and regression analysis were performed using SPSS. Also, independent t test, and Levene's test were used for ad hoc analysis to assess variation of food choice decisions over 30 days. Of the sample, 5% had low and 95% very low food secure status. Food security status did not predict coping strategies (p = .724); however, food security status and type of coping strategy had a moderate relationship (p < 0.01; r =.60). Food choices of 11 food categories changed over a 30-day cycle with greatest variation for Week 1, compared to Weeks 2â??4 (p < .005). Use of coping strategies to minimize hunger was limited. Very low food security associated with certain coping strategies disrupted eating patterns. Disrupted eating patterns affect food variation over time, increasing the intake of non-nutrient-dense foods and the risk of obesity and Type 2 diabetes. The implications for positive social change include the potential to change SNAP's benefit allotments, make nutrition education mandatory, and create a nutrition package, thereby lowering food insecurity and the risk of Type 2 diabetes.
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2

DiGiulio, Laura. "Food Policy Councils: Does Organization Type Matter." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1492620713327182.

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3

Acosta, Sanchez David. "White food-type sorghum in direct-expansion extrusion applications." Thesis, Texas A&M University, 2003. http://hdl.handle.net/1969.1/515.

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Whole sorghum kernels were directly processed into whole grain snacks with acceptable texture. Extrudates made from whole sorghum had a harder gritty texture than those made from decorticated materials. Extrusion of whole sorghum provides significant savings in processing: there are no dry matter losses; no equipment or energy is required for decortication or milling; the extruder consumes less power and processes more material per time unit. In addition, the extruder utilized is a simple adiabiatic, friction extruder of relatively low cost. Grinding whole sorghum and removing fines did not improve product expansion during extrusion but altered the gritty pieces in the extrudates. The best products were obtained when whole sorghum (ground or un-ground) was extruded at 14% moisture. The whole sorghum extrudates had larger bubbles with thick cell walls, which made extrudates more crunchy. Decortication of sorghum improved extrusion performance and products by allowing adequate formation and retention of air cells. Decortication to remove 20% of the original sorghum weight was enough to produce extrudates with characteristics comparable to those made from commercial yellow corn meal. Sorghum milled fractions with composition and particle size distribution similar to corn meal produced extrudates with higher expansion, lower bulk density and similar texture. In addition, sorghum extrudates were rated equal to corn meal extrudates by a taste panel for appearance, flavor, texture and overall characteristics. Extrudates made from polished rice were less expanded and whiter than extrudates made from sorghum. When processed under similar conditions, sorghum extrusion required more energy than corn meal extrusion. However, whole sorghum extrusion required less energy than corn meal extrusion. Unground sorghum samples (decorticated or non-decorticated) produced harder extrudates compared to those made from ground raw material. White sorghum is a feasible option for snack extrusion because of its versatility, product characteristics, cost and processing properties.
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4

Lenz, Possato Sarah. "Protein type and amount influences food intake in rats /." Available to subscribers only, 2007. http://proquest.umi.com/pqdweb?did=1402174401&sid=7&Fmt=2&clientId=1509&RQT=309&VName=PQD.

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5

Huerta-Gonzalez, L. "Interactions between lactic acid bacteria and lipids in milk type systems." Thesis, University of Reading, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242123.

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6

Bailey, Grace. "The Effect of Fast Food Restaurants on Type 2 Diabetes Rates." Scholarship @ Claremont, 2018. http://scholarship.claremont.edu/cmc_theses/1819.

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This paper conducts an analysis of county level data to determine the effect of fast food restaurants on type 2 diabetes rates. Due to endogeneity concerns with respect to the location of fast food restaurants, this paper follows the work of Dunn (2010) and uses the number of interstate exits in a given county to serve as an instrument for fast food restaurants. The strength of the instrument, which is theoretically and empirically tested in this paper, imposes some restraints on the interpretation of the findings. Using the Two-Stage Least Squares estimation method, I find that the presence of fast food restaurants has a positive and statistically significant effect on type 2 diabetes rates at the county level.
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7

McNeill, Meghan. "A Qualitative Study Exploring Food Pantry User’s Self-Management of Type 2 Diabetes." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1430749639.

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8

Md, Yasir Suhaimi Bin. "The role of protein cross-linking in soy food texture." Thesis, University of Canterbury. Biological Sciences, 2005. http://hdl.handle.net/10092/1388.

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Cross-linking in soy proteins is hypothesised to have an impact on the texture of tofu. In vitro incubation showed soy proteins and its two fractions, glycinin and β-conglycinin, were cross-linked using glutaraldehyde, formaldehyde, glyceraldehyde and transglutaminase (TGA). Increasing concentration of these carbonyl compounds and TGA, and temperature of the carbonyl compounds treatment, increased the reactivity of cross-linking. Glutaraldehyde was the most reactive in forming aggregated proteins, followed by formaldehyde and glyceraldehyde. Both carbonyl moieties of glutaraldehyde are believed to be essential for the rapid cross-linking reaction. In the unfractionated soy proteins, β-conglycinin had a higher reactivity than glycinin. In in vitro incubation using TGA, soy proteins served as good substrates for TGA, in which β-conglycinin was more susceptible to TGA than glycinin in the unfractionated soy proteins. The addition of TGA, and 1 and 2 mM glutaraldehyde prior to soymilk boiling in situ resulted in a small number of cross-linked proteins, which correspond to an increase in fracture force. The addition of glutaraldehyde after soymilk boiling resulted in a slight decrease in fracture force compared to the control. At higher concentrations of glutaraldehyde (15 and 30 mM), soy proteins were mostly cross-linked, regardless of addition before or after soymilk boiling. Highly cross-linked proteins resulted in a significant decrease in the fracture force. For TGA treatment, the fracture force was increased with increasing TGA concentration from 1000 to 5000 ppm, added either before or after soymilk boiling. However, the TGA treatment showed only a small quantity of cross-linking. It is hypothesised that TGA hydrolysed glutamine of proteins to glutamate and changed the functional properties of proteins. Upon examination of the microstructure, it was found that the TGA treatment resulted in a fine-stranded network, compact structure and less porosity. These characteristics resulted in a higher fracture force. In contrast, in the glutaraldehyde treatment, the network consisted of a higher porosity, loose network and diffuse structure, which gave lower fracture force. Thus, it appears that substrate modification to the structure of the soy proteins may have a greater impact than the number of cross-links. These findings are likely to have implications for production of soy products with a wide range of textures by manipulating the soy protein properties.
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9

Staus, Alexander [Verfasser]. "Determinants of Store and Store Type Choice in the Food Market / Alexander Staus." Aachen : Shaker, 2010. http://d-nb.info/1084535793/34.

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10

Gunasekaran, Nishkaran. "Effect of Fat Content and Food Type on Heat Transfer during Microwave Heating." Thesis, Virginia Tech, 2002. http://hdl.handle.net/10919/34844.

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Microwaves heat food rapidly and foods are prepared in less time. However, due to non-uniform heating nature of microwave cooking, there exists a serious concern over complete elimination of pathogens in the food. There has been an increase in interest to accurately understand the behavior of different food materials in a microwave field and microbial inactivation during microwave cooking. Recent research showed that fat content in muscle food plays an important role in microbial inactivation by increasing the inactivation level with an increase in the fat level. It was also demonstrated that muscle food heats up differently than a vegetable food product. Cooking food in a microwave oven either by covering the food container or not results in significantly different temperature profiles. The current research attempts to use modeling techniques to analyze impact of these factors on microwave heating. Mathematical modeling is faster, easier and economically better than actual experiments in determining heating behavior of a microwave-cooked food. Though modeling cannot completely replace actual experiments, it can be used as a tool to understand the effects of various factors influencing the microwave cooking. A factor that is highly important during microwave processing is dielectric properties of the material. The interaction of microwave with the food is mainly based on its dielectric properties, which can change with temperature. Therefore, determination of dielectric properties of food with respect to temperature becomes critical. The current research project has two parts. One to determine the dielectric properties of food being tested and another is to employ mathematical modeling techniques to analyze the effect of fat content, food type and the effect of cooking food by covering the bowl using the lid and not covering bowl. Dielectric properties of ground beef patties at 4%, 9%, 20% fat levels and frozen broccoli were determined using an open-ended, 3.6 mm diameter, semi-rigid coaxial line with copper conductors, connected to a network analyzer. The properties were determined at various temperatures. Foods were measured in triplicate. Results showed that dielectric constant and dielectric loss factor of low fat ground beef were higher than that of high fat level ground beef. In addition, the dielectric properties of florets were lower than that of stem parts for frozen broccoli. A 1,200W, household type microwave oven was used in this study to heat the food. Food was placed in a microwave-safe glass bowl and cooked for 120 seconds. One headspace and three internal temperature measurements were recorded for every 0.6 seconds. Five replications were performed. Finite element method was used as modeling technique and temperatures were predicted. Experimental and predicted temperature values were compared. Results showed that the model used in the study was more suitable for modeling the uncovered cooking than covered cooking process. Modeling results also revealed that high fat ground beef patties reached higher temperature than low fat patties. In high fat meat products, fat content also contributed to increase in temperature during microwave heating. In vegetable products and low fat meat food, moisture content is mainly responsible for microwave heating. A more extensive study on critical fat level above which fat content helps in increasing temperature is needed. In addition, inclusion of steam properties in the headspace for modeling the covered cooking is recommended.
Master of Science
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11

Mansouri, Abdelhak. "Hepatic fatty acid oxidation and control of food intake /." Zürich : ETH, 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17697.

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12

Linley, Moreland. "INVOLVEMENT OF TISSUE-TYPE PLASMINOGEN ACTIVATOR IN THE REGULATION OF CIRCADIAN RHYTHMS." Kent State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=kent1278950189.

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13

Arguelles, Mercedes C. "FOOD AND FOOD-DERIVED BIOACTIVE COMPOUNDS: RELEVANCE TO HOMEOSTASIS OF THE ANTIOXIDANT, CARDIOVASCULAR, AND IMMUNE SYSTEMS." Diss., Tucson, Arizona : University of Arizona, 2005. http://etd.library.arizona.edu/etd/GetFileServlet?file=file:///data1/pdf/etd/azu%5Fetd%5F1079%5F1%5Fm.pdf&type=application/pdf.

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14

Klockow-Beck, Antje. "Analysis of carbohydrates in food and glycoconjugates with capillary electrophoresis /." [S.l.] : [s.n.], 1995. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=11241.

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15

Subramanian, Ramachandran. "Merger Type and Performance: A Longitudinal Study of the Food and Kindred Products Industry." Thesis, University of North Texas, 1990. https://digital.library.unt.edu/ark:/67531/metadc935755/.

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The purpose of this study was to measure merger performance on a longitudinal basis using a micro perspective. Specifically, this study looked at the performance of a sample of mergers drawn from the food and kindred products industry, Standard Industrial Classification code 20, for a period of five years before and five years after the merger using two performance measures. The performance measures, namely market returns to stockholders and return on investment, have been used extensively in the literature to study the performance of mergers and acquisitions, albeit on macro samples. The study offered significant statistical support for the hypothesis that mergers benefit the acquiring firm and its stockholders, as well as for the hypothesis that merger performance in the latter time period of study (1977 to 1984) was better than in the former (1968 to 1977). However, no significant difference in performance was found across merger types. The study discussed the managerial implications of these findings and offered directions for future research in the area of merger performance.
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16

Inuzuka, Megumi. "C-type Natriuretic Peptide as a New Regulator of Food Intake and Energy Expenditure." Kyoto University, 2010. http://hdl.handle.net/2433/126777.

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17

Hix, April. "Effect of Evaporative Cooling, Fat Content and Food Type on Pathogen Survival during Microwave Cooking." Thesis, Virginia Tech, 2000. http://hdl.handle.net/10919/35830.

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Due to the rapid nature of microwave heating, the microbiological safety of foods prepared in the microwave has been in question for several years. Because foods are heated from the inside out and are strictly governed by their own internal properties such as ionic content, moisture level and specific heat, work must be done to further master control of such properties so microwave cooking can be more predictable, controlled and ensure control pathogens. This study concentrated on the effect of fat content, evaporative cooling and food type on the rate of food borne pathogen survival rates in microwave heated foods. Foods investigated in this study included fresh, raw broccoli spears; a regular, whole muscle breaded chicken patty and a fat free, breaded, formed chicken patty; and raw ground beef patties at three differing fat percentages. All foods were tested in triplicate. A Sharp® 1000W Light-Duty Commercial Microwave Oven was used to treat inoculated samples according to their recommended cooking times. Two sets of samples were treated, one wrapped with Saran⠢ Wrap and the other without wrap. F-values were determined for each product. Raw ground beef patties at fat contents of 30%, 15% and 7%, heated for the same time had F-values ranging from 0.03 to 126.20. The lower the fat content, the lower the lethality. Regular and fat free chicken tenders had similar patterns. F-values for fresh broccoli indicted that vegetative pathogens survived the recommended microwave process. Covering in Saran⠢ Wrap had some preventive effect on evaporative cooling depending on the food tested and significantly (p < 0.05) increased most F-values. Inoculated pack studies were performed in triplicate on each food with Listeria monocytogenes, Salmonella and Escherichia coli O157:H7. Survival was determined by presence or absence of growth of each pathogen after enrichment. Listeria monocytogenes survived in all samples except for the 30% fat ground beef patties. The Salmonella species had a lower survival rate; however, it was still present in uncovered 15% fat ground beef, covered 7% fat ground beef, uncovered chicken patties (both types) and in all broccoli samples tested. E. coli O157:H7 survived in all samples except the 30% fat ground beef samples. Results indicate that higher fat contents seem to ensure lower rates of pathogen survival. This was especially true for the raw ground beef, which had received no prior processing other than the grinding of the whole muscle. There were fewer survival differences in the preprocessed, frozen chicken patties. Both were shown to support no pathogen survival in covered samples, except the fat free chicken patties. Listeria monocytogenes was shown to consistently survive the suggested cooking time in these samples. This is consistent with expectations that fat free food samples would display more survival than regular fat samples. Overall, covering samples with Saran⠢ had little effect on pathogen survival rates. There were survival differences in some covered and uncovered samples consistent with expectations that covered samples would show less survival than uncovered, but further work including more samples would be necessary to ensure that the covered or uncovered variable made the true difference in pathogen survival. Finally, broccoli demonstrated consistent pathogen survival in all categories of testing. This indicates microwave oven prepared vegetables could be a prime source of pathogen transmission to consumers. Further work needs to concentrate on determining the correct processing times and parameters that need to be met to ensure safe food.
Master of Science
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18

Surina-Baumgartner, Denise M. "Fatty acid oxidation and insulin in the control of food intake /." [S.l.] : [s.n.], 1995. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=11083.

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19

Hoppler, Matthias. "Content and bioavailability of ferritin-bound iron in staple food crops /." Zürich : ETH, 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=18038.

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20

Patel, Pinal Suryakant. "Epidemiological evidence for an association between the amount and type of fish intake and the risk of type 2 diabetes." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610422.

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21

Loucks, Jessilee Noel. "The Effect of Monetary Reward and Food Type on Motivation of Untrained Sensory Panelists in Triangle Tests." BYU ScholarsArchive, 2016. https://scholarsarchive.byu.edu/etd/5794.

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Although human panelists provide unparalleled data, they are prone to bias, which is a primary concern of sensory scientists. Motivational bias is of concern because it determines how much effort a panelist will exert to be consistent, find a difference, or use appropriate descriptors when taking a test. For central location tests, money has become a common motivational device to compensate panelists for their time and effort. Studies have documented that money can change results in sensory testing but have not measured the impact on motivation. Additionally, little research has been conducted on the effect of the test food itself as a motivator. This scientific investigation explored monetary reward and the test food type as motivational factors to examine how these affected untrained panelist effort. Panelist accuracy on a triangle test and assessment time to complete the triangle test were measured as the response variables. Two models were generated using the two response variables, and both were adjusted for panelist age, gender, liking, time of day, and day of the week. Statistical analysis indicated that monetary compensation was not a primary motivational factor for untrained sensory panelists, but might play a role in panelist attendance. Food type impacted models differently showing its importance but also making results inconclusive. Other factors like gender, age, time of day, and day of the week were significant to a panelist's motivation and may be related to things like food involvement and workday accumulation, but more research is needed to further support these ideas. In addition to the study at hand, three preliminary studies were completed prior to obtaining the results in the main study. First, surveys gathering data on general liking of different foods were conducted. Triangle tests were then completed on potential products to confirm that treatments created for foods were not too obvious for panelists. The last preliminary step was to confirm that all differences used for treatment differences per product type were similarly different, even though not similar in nature. Difference from control tests were conducted on each product and its treatments to find how different a product's treatments were from each other. Eventually, we were able to verify that between all treatment difference couples for all products were similarly different by keeping the individual differences between a range of 10 points or 10% of a 100-point scale.
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22

Tietz, Melanie. "Starch-flavour interactions : impact on flavour retention and release in model food systems /." Zürich : ETH, 2007. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17517.

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23

Rungarara-Keenan, Margareth. "Culture and diet : food choice among Black African and African-Caribbean women with Type 2 Diabetes." Thesis, University of Essex, 2016. http://repository.essex.ac.uk/16866/.

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People of Black African heritage in the UK have increased susceptibility of being diagnosed with Type 2 Diabetes Mellitus (T2DM) compared to the general White population. Nutrition is central in halting T2DM and the progression of complications such as cardiovascular diseases. However, little is known about the factors influencing the diet of women of Black African heritage with T2DM. In addition, clinical and public health conceptions of the problem tend to be individualistic in orientation. This study is an exploratory and in-depth inquiry into food choice and the implications of dietary change for women of Black African heritage who self-manage T2DM by diet alone. Eight participants were recruited using purposive sampling. Recruitment sites included Black and Minority Ethnic charities in Norfolk and Suffolk. Data was derived from direct observation using the ‘Accompanied Shopping Task’, combined with a ‘Think Aloud Technique’ called a ‘Product Choice Reasoning Task’. In-depth interviews were undertaken and transcribed verbatim. Framework Analysis was used to provide a procedure to manage data analysis, which was informed by the PEN-3 public health cultural model which moves beyond overly individualistic conceptions of the issues. The study showed that six participants prioritised the disease and used what I have called a ‘Disease Focused Approach’ to self-manage T2DM. Two used a ‘Family Focused Approach’, as family played a crucial role in T2DM self-management. All participants undertook T2DM self-care by following a culturally appropriate diet. Their least preferred options for managing T2DM were medical therapy and physical activity. The study showed that although food choice is influenced by many factors, culture was particularly important. Moreover, participants showed greater knowledge than had been anticipated about the role of nutrition to prevent progression of T2DM. Results are explored and presented for three main domains of experience for the participants: first, food shopping and decision-making; second, diet choice and lifestyle; and third, the interface with health services. For each of these the culture was found to be of paramount importance. The implications of the findings are presented in relation to the importance of culturally appropriate advice; culturally sensitive service provision; and the significance of household composition in managing the illness, especially for people with T2DM who have young children living at home.
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McDermid, Ann Sheena. "The influence of pH on the survival and pathogenicity of Salmonella enteritidis phage-type 4." Thesis, Open University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264476.

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25

Matzinger, Daniel Andreas. "The role of fat in regulating food intake in humans : potential mechanisms of action /." [S.l.] : [s.n.], 1999. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=13303.

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26

Miner, Cheryl Ann. "Maternal, Neonatal and Feeding Type Factors Associated with Severity of Necrotizing Enterocolitis." BYU ScholarsArchive, 2011. https://scholarsarchive.byu.edu/etd/3097.

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Objective: To identify statistical associations with necrotizing enterocolitis (NEC) severity as dichotomized into cases with Bell stage II and III disease. Study Design: We conducted a retrospective study using eight consecutive years of data from a multihospital healthcare system analyzed NEC severity (Bell stage II vs. III). Results: We identified 220 neonates with stage ≥ II who had 225 separate episodes of NEC (157 stage II and 68 stage III). Those with stage III were born at earlier gestational age (P<0.0001) and lower birth weight (P<0.0001). Diagnosis of NEC occurred on about the same day of life in stage II and stage III cases. Those who developed stage III had significantly higher C-reactive protein (P<0.0001), I/T ratio (P= 0.0005), mean platelet volume (MPV) (P= 0.0001) and lower pH (P<0.0001) and platelet counts (P<0.0001). Transfusions were more common to those who progressed to stage III (P<0.0001). Regression analysis indicated higher odds of stage III in relationship to the volume of RBC transfusions (OR 2.41, {CI 1.85 to 3.11}, P<0.0001) and pasteurized human milk (PHM) (OR 1.32, {CI 1.07 to 1.62}, P = 0.0089). In contrast, feeding early mother's own milk (colostrum) for five days reduced the odds for stage III (OR 0.802, {CI 0.67 to 0.96}, P=0.0170). Those with small bowel resection were less likely to have received mother's own milk before NEC (OR 0.94, {CI 0.89 to 0.99}, P = 0.019) and factors predicting death from NEC were a low pH (OR 2.21, {CI 1.27 to 3.85}, P = 0.0005) and less colostrum (OR 0.96, {CI 0.94 to 0.99}, P = 0.003). Conclusions: RBC transfusions and PHM increased the odds for stage III NEC, whereas early mother's own milk five days reduced the odds. Mother's own milk with PHM decreased the risk for small bowl resection and early mother's milk decreased the odds for mortality from NEC. Future research and prospective randomized controlled studies are needed to quantify any reduction in NEC severity on the basis of decreasing RBC transfusions and increasing early mother's own milk or colostrum.
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Boisclair, Daniel. "Among-population variability in fish growth rates : the influence of food consumption, prey type and fish community." Thesis, McGill University, 1988. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=75957.

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I assessed the relationship between growth of fish in situ, food consumption, prey type and fish community descriptors in 12 perch (Perca flavescens) populations exhibiting a 1.8 to 10-fold range in growth rates.
Perch growth rates consistently decreased as fish numerical density increased (r$ sp2$ = 0.60) and increased as feeding levels increased (r$ sp2$ = 0.30). I found no significant relationship between the quantity of food consumed by perch and fish numerical density. Prey quality explained from 50 to 95% of the observed variability in growth but was related to fish numerical density in only one of the 3 perch age classes studied.
I conclude that non-exploitative interactions (operating through increased activity costs) is a more viable explanation for the among-population variability in fish growth rates than is exploitative competition (yielding decreases in the total quantities of food consumed and/or prey quality).
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28

Liu, Junguo. "Modelling global water and food relations : development and application of a GIS-based EPIC model /." Zürich : ETH, 2007. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17069.

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29

Ma, Zhen. "Techno-functional and sensory properties of salad dressing-type emulsion prepared with pulse flours and pulse fractions." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114459.

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Pulses, the low-fat dried seeds of legumes, including peas, chickpeas, lentils, beans and lupins, have received increased attention due to their numerous health-promoting benefits. Significant opportunities exist for using whole pulses as well as their fractions in a variety of innovative value-added food products. Salad dressings, which are important oil-in-water emulsions, account for a large part of the semi-solid foods market and are widely consumed in North America and in many other countries. The development of salad dressings supplemented with pulse flours and pulse fractions represents a novel avenue of study with great potential for improving the techno-functional and nutritional quality of salad dressing products by enhancing protein, fibre, vitamin and mineral content and, in some cases, promoting amino acid complementation.Salad dressing emulsions supplemented with raw and thermally treated pulse flours were developed. The effect of pulse addition on the dressing formulations was studied by comparing the physical properties of dressings prepared with or without supplementation. The results showed that lentil flours have considerable potential for use as an ingredient in salad dressings. The rheological parameters were significantly increased, pointing to a thickening effect associated with pulse flour supplementation. Pre-boiling of pulse flours further increased the thickening effect, giving the highest rheological properties observed. The relationship between the physical properties and structural characteristics was explored by comparing the rheological behaviour and the scanning electron microscope observations. The results of the quantitative descriptive analysis (evaluation of firmness) were consistent with the rheological data. All the dressings maintained acceptable stability over 28 days of storage. With respect to dressing appearance, lentil supplementation significantly increased the yellowness hue and the total colour intensity of the dressing samples. The effects of reducing the fat and cholesterol (egg yolk) contents of the supplemented dressings, as well as increasing the amount of pulse flour added, upon the color and rheological properties were investigated by using a central composite design and response surface methodology. The results showed that changes in the main ingredients had a large effect on the responses observed. The scanning electron microscope results indicated that the dressings with lower oil and egg yolk contents had a less densely packed network and looser aggregated droplets. This finding was in good agreement with the observed response surface plots of the rheological parameters. Consumer sensory tests on showed that the dressings supplemented with whole green lentil flour, low concentrations of yellow pea flour, and chickpea flour with high oil content hold promise for commercial applications. The results should prove useful in selecting the most suitable ingredients for the production of supplemented salad dressings. Additionally, pulse protein fractions derived from green lentil, yellow pea and Desi chickpea were used in the preparation of pulse-supplemented dressings. The response surface plots showed that an increase in oil and emulsifier (pulse protein or egg yolk) concentration led to a linear or non-linear increase in the rheological and textural properties. Response surface methodology was used to optimize the salad dressing formulations based on selected response (dependent) variables. The validation test confirmed the overall adequacy of this modelling approach for predicting the behaviour of the dressing systems under different factor combinations, with the ultimate goal of meeting market specifications. The research work underpinning this thesis provides information to support the development of whole pulse flours and pulse fraction supplemented dressings with nutritional and techno-functional potential for commercial and industrial applications.
Les légumineuses (sous forme de graines sèches avec une faible teneur en gras) tel que les petits pois, les pois chiches, les lentilles, les haricots et les graines de lupins, ont reçu une attention accrue en raison de leurs nombreux avantages favorables à la santé. Il existe plusieurs façons d'utiliser les légumineuses entières ainsi que leurs fractions dans une variété de produits alimentaires innovants à haute valeur ajoutée. Les vinaigrettes, qui sont des émulsions huile-en-eau, représentent une grande partie du marché des aliments semi-solides et sont largement consommés en Amérique du Nord ainsi que dans de nombreux autres pays. Le développement de vinaigrettes supplémentées avec des farines de légumineuses ou des fractions de légumineuses représente une nouvelle avenue avec un grand potentiel pour améliorer la qualité technico-fonctionnelle et nutritionnelle des vinaigrettes en augmentant la teneur en protéines, en fibres, en vitamines et minéraux, et dans certains cas complémentant les acides aminés du produit. Des émulsions de vinaigrettes supplémentées avec des farines de légumineuses brutes et traitées thermiquement ont été développées. L'effet de l'addition de légumineuses dans les formulations des vinaigrettes a été étudié en comparant les propriétés physiques des vinaigrettes préparées avec ou sans supplémentation. Les résultats ont montré que les farines de lentilles ont un potentiel considérable comme ingrédient dans les vinaigrettes. Les paramètres rhéologiques ont été considérablement augmentés, montrant un effet d'épaississement associé à la supplémentation de la farine de légumineuses. L'addition de farines de légumineuses pré- bouillies a en outre augmenté l'effet épaississant, conduisant à des propriétés rhéologiques observées plus élevées. La relation entre les propriétés physiques et les caractéristiques structurelles a été explorée en comparant le comportement rhéologique et les observations faites à l'aide d'un microscope électronique à balayage. Les effets de la réduction des matières grasses et du cholestérol (jaune d'oeuf) dans les vinaigrettes supplémentées et de l'augmentation de la quantité de farine de légumineuses ajoutée, sur la couleur et les propriétés rhéologiques ont été étudiés en utilisant un plan central composite et une méthode de surface de réponse. Les résultats ont montré que des changements des principaux ingrédients ont eu un effet important sur les réponses observées. Les résultats au microscope électronique à balayage ont indiqué que les vinaigrettes contenant moins d'huile et de jaune d'œuf disposaient d'un réseau moins dense et des gouttelettes agrégées plus souples. Cette constatation est en accord avec les courbes de surface de réponses observées pour les paramètres rhéologiques. Les courbes de surface de réponses ont montré que l'augmentation de la concentration de l'huile et de l'émulsifiant (protéine de légumineuse ou le jaune d'œuf) conduit à une augmentation linéaire ou non linéaire dans les propriétés rhéologiques et texturales. La méthode de surface de réponse a été utilisée pour optimiser la formulation des vinaigrettes et a été basée sur les variable réponses (dépendantes) choisies. Le test de validation a confirmé la pertinence globale de cette approche de modélisation pour prédire le comportement des systèmes vinaigrettes avec différentes combinaisons de facteurs, dont le but ultime est de répondre aux spécifications du marché.Les travaux de recherche de cette thèse fournissent des informations importantes et pertinentes pour permettre le développement de vinaigrettes supplémentées avec des farines de légumineuses entières ou avec des fractions protéiques avec un potentiel nutritionnel et techno-fonctionnel intéressants pour des applications commerciales et industrielles.
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30

Spooner, Holly Sue. "Hydration status of endurance horses as affected by dietary fiber type with and without supplemental fat." Diss., Connect to online resource - MSU authorized users, 2008.

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31

Singleton, Tyler J. "The Effect of Exopolysaccharide-producing Streptococcus thermophilus MR1C on Functionality in High Moisture Cheddar-type Cheese." DigitalCommons@USU, 2007. https://digitalcommons.usu.edu/etd/5537.

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Differences in texture at any particular stage of ripening depend upon differences in the basic structure and the extent to which the basic structure is modified by physical parameters. Thus, very young cheeses of the same variety differ in texture because of variations in pH and in salt, moisture, and fat content. How well a cheese melts and shreds depend on its texture and physical parameters. Streptococcus thermophilus MR1C produces an exopolysaccharide (EPS) that is tightly associated with the bacterial cell wall. Addition of S. thermophilus MR1C to the cheese make will increase the moisture of the cheese 2-3% and thus affect the texture, melt, and shreddability of that cheese. To determine the effect of S. thermophilus MR1C on the texture, melt, and shreddability of cheese, two stirred-curd cheeses with equivalent physical parameters using BPS-producing S. thermophilus MR1C or non-BPS-producing S. thermophilus DM10 adjunct cultures were produced. Because MR1C cheese would increase moisture, the curd size, wash water temperature, and pH at salting had to be altered in order to make the physical parameters the same for both cheeses. The MR1C cheese was harder and had a higher fracture stress than the DM10 cheese. The MRlC cheese was also more adhesive, but only for one of the two trials. Even with adjustments in the method of manufacture, the MR1C cheese still had a slightly higher SM and pH, which may be partly responsible for the differences between the two cheeses. There were no differences between the MRlC cheese and the DM1 0 cheese in shreddability as determined by fines, stickiness, and gumminess. Cheese produced without a streptoccus adjunct culture was more cohesive and had fewer fines than the MRIC or DM10 cheese.
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AIR, ELLEN LOUISE. "THE MECHANISMS THROUGH WHICH INSULIN AND AN INSULIN-MIMETIC REGULATE FOOD INTAKE AND BODY WEIGHT." University of Cincinnati / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1021213893.

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33

Heller, Hansraj Christine. "Trophic cascading in Lake Lucerne, Switzerland : the influence of top-down controls on the pelagic food web /." [S.l.] : [s.n.], 2000. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=13631.

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34

Lodefalk, Maria. "Adolescent type 1 diabetes : Eating and gastrointestinal function." Doctoral thesis, Karolinska institutet, Stockholm, Sweden, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-46180.

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Adolescents with type 1 diabetes (T1DM) are given nutritional education, but the knowledge about their adherence to the food recommendations and associations between dietary intake and metabolic control is poor. Gastrointestinal symptoms are more prevalent in adults with T1DM than in healthy controls, which may be due to disturbed gastrointestinal motility. The meal content affects the gastric emptying rate and the postprandial glycaemia in healthy adults and adults with type 2 diabetes. Meal ingestion also elicits several postprandial hormonal changes of importance for gastrointestinal motility and glycaemia. Eating disorders are more prevalent in young females with T1DM than in healthy females, and are associated with poor metabolic control. The prevalence of eating disorders in adolescent boys with T1DM is not known.  This thesis focuses on eating and gastrointestinal function in adolescents with T1DM. Three population-based, cross-sectional studies demonstrated that adolescents with T1DM consume healthy foods more often and have a more regular meal pattern than age- and sex-matched controls. Yet both boys and girls are heavier than controls. The intake of saturated fat is higher and the intake of fibre is lower than recommended in adolescents with T1DM. Patients with poor metabolic control consume more fat and less carbohydrates than patients with better metabolic control. Gastrointestinal symptoms are common in adolescents with T1DM, but the prevalence is not increased compared with controls. Gastrointestinal symptoms in patients are associated with female gender, daily cigarette smoking, long duration of diabetes, poor metabolic control during the past year, and an irregular meal pattern. Adolescent boys with T1DM are heavier and have higher drive for thinness than healthy boys, but do not differ from them in scales measuring psychopathology associated with eating disorders.   In a randomized, cross-over study, we found that a meal with a high fat and energy content reduces the initial (0–2 hours) postprandial glycaemic response and delays gastric emptying in adolescents with T1DM given a fixed prandial insulin dose compared with a low-fat meal. The glycaemic response is significantly associated with the gastric emptying rate. Both a high- and a low-fat meal increase the postprandial concentrations of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) and suppress the postprandial ghrelin levels in adolescents with T1DM. The postprandial changes of these hormones are more pronounced after the high-fat meal. Insulin-like growth factor binding-protein (IGFBP) –1 concentrations decrease after insulin administration irrespective of meal ingestion. The GLP-1 response is negatively associated with the gastric emptying rate. The fasting ghrelin levels are negatively associated with the postprandial glycaemic response, and the fasting IGFBP-1 levels are positively associated with the fasting glucose levels.  We conclude that nutritional education to adolescents with T1DM should focus more on energy intake and expenditure to prevent and treat weight gain. It should also focus on fat quality and fibre intake to reduce the risk of macrovascular complications and improve glycaemia. Gastrointestinal symptoms in adolescents with T1DM should be investigated and treated as in other people irrespective of having diabetes. However, adolescents with long duration of diabetes, poor metabolic control, and symptoms from the upper gut should have their gastric emptying rate examined during euglycaemia. There may be an increased risk for development of eating disorders in adolescent males with T1DM since they are heavier than healthy boys and have higher drive for thinness. This should be investigated in future, larger studies.  For the first time, we showed that a fat-rich meal delays gastric emptying and reduces the initial glycaemic response in patients with T1DM. The action profile of the prandial insulin dose to a fat-rich meal may need to be postponed and prolonged compared with the profile to a low-fat meal to reach postprandial normoglycaemia. Circulating insulin levels affect postprandial GIP, GLP-1, and ghrelin, but not IGFBP-1, responses less than the meal content. The pronounced GIP-response to a fat- and energy-rich meal may promote adiposity, since GIP stimulates lipogenesis. Such an effect would be disadvantageous for adolescents with T1DM since they already have increased body fat mass and higher weights compared with healthy adolescents. Adolescents with T1DM may have subnormal postprandial ghrelin suppression, which may be due to their increased insulin resistance or elevated growth hormone levels. This needs to be investigated in future, controlled studies.
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35

Halbrook, Courtney (Courtney Ann). "A Laboratory Study of the Asiatic Clam (Corbicula fluminea Müller) as Influenced by Substrate, Food Source and Water Type." Thesis, University of North Texas, 1995. https://digital.library.unt.edu/ark:/67531/metadc279067/.

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Growth of Corbicula fluminea was monitored in the laboratory. Three experiments were conducted. Experiment I utilized three substrates and one food type. Experiment II utilized three substrates and two food types. Experiments I and II were conducted to determine if substrate type or food type effected growth. Experiment III used no substrates, one food type and was conducted to determine growth response to different types of water. Clams were maintained in three substrates: sand, gravel and clay. Clams were also maintained without substrate. Growth was monitored by measuring shell length (mm) and recording the weight (mg) of clams over a period of thirty days. At the end of the test period data were evaluated for normality and homogeneity.
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36

Chikuta, Maxwell K. "Preventing Obesity and Type 2 Diabetes in Immigrant Populations." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/6541.

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Obesity-related diseases have been increasing in African immigrants throughout the United States. Although research has been done to identify risk factors associated with many ethnic groups in the United States, only a few studies exist that explore obesity and type 2 diabetes diseases among Central African immigrants. The conceptual framework for this qualitative case study was social constructivism and the health belief model. The primary research question addressed the potential underlying causes for an increase in obesity and type 2 diabetes among Central African Immigrants. The secondary research questions explored how culture, illiteracy, and religion contribute to the problem of obesity in Central African immigrants, and what strategies could be effective in preventing and reducing the increase of obesity and type 2 diabetes in this population. Interviews with 17 Central African immigrants living in the northeastern U.S. were conducted to explore their social, cultural, and behavioral factors that influence the prevalence of obesity. Interview responses were transcribed and entered into NVivo software for data analysis. The results revealed that socioeconomic issues, cultural differences, and language gaps were the primary risk factors. Feeling stressed and overwhelmed and a lack of communication were also found to be significant. The results could provide health administrators and health educators with a platform for advancing policies and programs to foster greater health and well-being among Central African immigrants and thus contribute to the overall social welfare of Central African immigrants.
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Porqueddu, Tania. "Ethnographic investigation of the impact of type 2 diabetes among Indian and Pakistani migrants." Thesis, University of Edinburgh, 2013. http://hdl.handle.net/1842/9754.

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This thesis explores the impact of type 2 diabetes among Indian and Pakistani migrants. Indians and Pakistanis living in the UK have a high incidence of type 2 diabetes and associated complications. Research is needed in order to understand factors that make it difficult to adhere to lifestyle advice about diet, exercise and medication. Drawing on data collected during a sixteen-month ethnographic investigation, this thesis explores Indians’ and Pakistanis’ perceptions of diabetes. The research revealed that Indians and Pakistanis related the onset of diabetes to processes of migration and settling in the UK as well as to stress and depression. In particular, holding on to negative thoughts and worries, were perceived by respondents as directly affecting the body by causing stress, depression and eventually illness. Struggles over diabetes control were also perceived as to cause distress. Specifically, respondents struggled to adhere to a healthy diet regime, since food, especially taste, played a crucial role in forming, reinforcing and demarcating social relations and in ensuring cultural continuity. In addition, respondents struggled to ‘adhere’ to their prescriptions of diabetes medications due to the uncomfortable side effects that they experienced, particularly in the stomach. Respondents, however, counteracted side effects by turning to alternative medications which were perceived to facilitate flow within the circulatory and digestive system. Thus, in spite of the difficulties that Indians and Pakistanis experienced in following biomedical recommendations for diabetes control, they still actively engaged in searching and using different treatments available to them in order to control the disease.
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38

Gutbrodt, Bettina. "Diet composition of wildebeest, waterbuck and reedbuck in relation to food quality in a moist savanna of Tanzania /." Zürich : ETH, Eidgenössische Technische Hochschule Zürich, [Institut für Integrative Biologie], 2006. http://e-collection.ethbib.ethz.ch/show?type=dipl&nr=290.

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39

Huggins, Michele. "An exploration of the implicit food attitudes of people with Type-1 Diabetes using reaction-time and electrophysiological measures." Thesis, University of Birmingham, 2011. http://etheses.bham.ac.uk//id/eprint/2880/.

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People with type-1 diabetes mellitus (T1DM) have to be aware of their dietary intake for health reasons and this study aims to investigate whether their food attitudes are different from non diabetic controls. Adult participants with T1DM (n = 12) and non diabetic controls (n = 12) were recruited to this affective priming study on food attitudes. Participants were exposed to picture primes from 3 food categories (high-fat sweet, high-fat savoury and low-fat) and to pictures of non-food items (i.e. chair, ball). Brain activity was recorded during the affective priming task using EEG to explore electrophysiological differences between the groups. The results found positive implicit and explicit attitudes towards all food-types with no group differences. The EEG data focussed on N200, P300 and LPP ERP’s and group differences were observed for the N200 ERP. The T1DM group demonstrated a larger N200 than the control group in all food and non-food conditions suggesting that there are electro cortical differences in brain functioning between these two groups and reasons for this difference are presented.
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40

Aldryhm, Yousif N. "An ecological study of the Indian meal moth, Plodia interpunctella Hbn, with emphasis on the effect of food type /." The Ohio State University, 1985. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487262825075745.

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41

Hu, Feifei. "Application of High Performance Liquid Chromatography (HPLC) and Fourier Transform Infrared (FTIR) Spectroscopy to Swiss-type Cheese Split Defects." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1343392495.

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42

Engels, Stéphanie Véronique. "Determinants of environmental innovations in the Swiss and German food and beverage industry : what role does environmental regulation play? /." Zürich : ETH, 2007. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17465.

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43

Zheng, Jinsen. "NITROGEN MANAGEMENT IN MAIZE-BASED SYSTEMS OF THE TANZANIAN HIGHLANDS: BALANCING FOOD AND ENVIRONMENTAL OBJECTIVES." Kyoto University, 2019. http://hdl.handle.net/2433/236626.

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付記する学位プログラム名: グローバル生存学大学院連携プログラム
Kyoto University (京都大学)
0048
新制・課程博士
博士(農学)
甲第21465号
農博第2308号
新制||農||1064(附属図書館)
学位論文||H31||N5160(農学部図書室)
京都大学大学院農学研究科地域環境科学専攻
(主査)教授 舟川 晋也, 教授 間藤 徹, 教授 縄田 栄治
学位規則第4条第1項該当
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44

Culley, Amanda A. "Knowledge and Perceptions of a Plant-Based Diet Among Individuals with Type 2 Diabetes and High Food Security Living in Rural Appalachian Ohio." Ohio University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1447871209.

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45

Spires, Mark Haydn. "Community insights into, and an international perspective on the role food environments and diet play in the self-management of type 2 diabetes mellitus in urban and rural South Africa." The University of the Western Cpae, 2018. http://hdl.handle.net/11394/6470.

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Philosophiae Doctor - PhD
Type 2 diabetes mellitus (T2DM) and pre-diabetes contribute increasingly to the global burden of disease. Along with other behavioural risk factors, diet plays a key role in the onset and management of the disease, in turn largely determined by what foods are immediately accessible in local food environments. With this in mind, this thesis aims to answer the research question: What role do local food environments play in promoting or inhibiting access to healthy foods as part of the self - management of T2DM in urban and rural communities in South Africa, and what can be learned from an international perspective? Specific research objectives include, to: 1. Understand the current national-level policy context with regard to the observed rise in NCDs, their proximal determinants (specifically an observed change in diet patterns), and contributing environmental factors; 2. Identify the current food-related environmental factors associated with the onset and/or management of T2DM in an urban and a rural setting (as well as in four additional international settings in order to provide an international perspective); 3. Explore community perspectives of the role the local food environment plays in the self-management of T2DM in an urban and a rural setting; and, consequently 4. Recommend intervention- and/or policy-related actions that can be implemented based on study findings. A review of the literature and relevant policies was conducted towards achieving the first research objective. Quantitative data were systematically collected at an urban and rural site in South Africa through the creation of an ‘environmental profile’ in an attempt to achieve the second objective – comparable urban and rural data was also collected as part of a larger study at two other international sites (Kampala, Uganda and Stockholm, Sweden) to provide an international perspective. Included in the third objective is the collection of qualitative data through a community based participatory research method at the same urban and rural sites in South Africa. Finally, intervention and/or policy-related recommendations are developed based on study findings and in consultation with relevant stakeholders through interviews.
2018-12-14
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46

Wahlberg, Jeanette. "Environmental determinants associated with Type 1 diabetes-related autoantibodies in children /." Linköping : Linköpings universitet, 2005. http://www.bibl.liu.se/liupubl/disp/disp2005/med922s.pdf.

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47

Kokot-Helbling, Karin Susanne. "Critical kinetic aspects of lipophilic compounds : I. Volatile organic compounds as food contaminants : II. Musk xylene in humans and laboratory animals /." Zürich, 1995. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=11152.

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48

Domingo, Rodriguez Laura 1992. "Neurobiological mechanisms involved in the loss of control over food intake." Doctoral thesis, Universitat Pompeu Fabra, 2020. http://hdl.handle.net/10803/668410.

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The easy access to palatable foods is a major contributing factor for compulsive eating and development of food addiction, a disorder closely linked to obesity and binge eating disorder. The concept of food addiction is still controversial but a validated tool for diagnosis, the Yale food addiction scale (YFAS 2.0), is widely accepted. However, the complex multifactorial nature of this disorder and the unknown neurobiological mechanistic correlation explain the current lack of effective treatments. In this thesis, we used a food addiction mouse model to elucidate the crucial role of the glutamatergic cortico‐striatal pathways modulated by the endocannabinoid and the dopamine systems as a critical mechanism for the loss of inhibitory control for palatable food seeking. This result was supported by electrophysiological recordings, genome‐wide RNA and DNA methylome sequencing, chemogenetic interference and adenoviral gene delivery, giving an understanding of the food addiction construct at genetic, epigenetic, cellular, circuit and behavioral level. This thesis unravels a new neurobiological mechanism underlying resilience and vulnerability to develop food addiction, which is expected to pave ways for novel interventions to battle compulsive eating behavior and other related disorders.
El fàcil accés a aliments altament saborosos és un factor important que contribueix a la ingesta compulsiva i al desenvolupament de l’addicció al menjar. Aquest trastorn està molt vinculat a l’obesitat i al trastorn per afartament. El concepte d’addicció al menjar és controvertit, però l’aparició d’una eina diagnòstica valida, el Yale food addiction scale (YFAS 2.0), ha sigut àmpliament acceptada. Tot i això, la naturalesa complexa i multifactorial d’aquest trastorn i la desconeguda correlació neurobiològica expliquen la manca actual de tractaments efectius. En aquesta tesi, hem utilitzat un model d’addicció al menjar en ratolins per descobrir el paper crucial de les vies cortico‐estriatals glutamatergiques modulades pels sistemes endocannabinoid i dopaminèrgic com a mecanisme clau per a la pèrdua del control inhibitori en la cerca d’aliments saborosos. Aquest resultat, amb el suport d’estudis electrofisiològics, seqüenciació d’ARN i d’ADN de tot el genoma i tècniques de “chemogenetics” ens donen una comprensió del trastorn a nivell genètic, epigenètic, cel·lular, de circuit i de comportament. Aquesta tesi revela un nou mecanisme neurobiològic subjacent a la resiliència i a la vulnerabilitat a desenvolupar addicció al menjar. S’espera que obri noves vies eficients d’intervenció per combatre el comportament d’ingesta compulsiva i altres trastorns relacionats.
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49

Davids, Rebecca Susanne. "Identifying food constituents that may improve cardiovascular disease risk factors in persons with or at risk for type 2 diabetes mellitus." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ56316.pdf.

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50

Sundell-Rånby, Birgitta. "Food intake, fibrinolysis and risk factors for cardiovascular disease : studies with special focus on plasminogen activator inhibitor type 1 (PAI-1)." Doctoral thesis, Umeå universitet, Patologi, 1993. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-101290.

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Elevated plasminogen activator inhibitor (PAI-1) activity levels, hyperlipemia, hypertension, impaired glucose tolerance and obesity, in particular central obesity, are all related to increased risk for the development of cardiovascular disease.Some risk factors are known to be and shown to be influenced by dietary habits. One aim of this study was to determine the distribution of PAI-1 activity and its linkage to serum lipids, body build, glucose and insulin (including glucose tolerance) among healthy men and women. Another aim was to elucidate the effects of different diet programes on the relationship between PAI-1 activity, serum lipid, glucose and insulin levels. Two cross-sectional studies, involving 260 individuals, the Norsjö study 1986, the mean PAI-1 activity among 30-60 year-old men was 7.9 U/mL and among women 7.8 U/mL. Both men and women with a body mass index over 27 kg/m2 had higher PAI-1 activity, tPA antigen, fasting insulin and insulin responses following an oral glucose tolerance test than persons with body mass index <27. They also had lower HDL-cholesterol. Women with a high waist/hip circumference ratio had a higher mean PAI-1 activity, tPA antigen, triglyceride, blood pressure and insulin response to an oral glucose tolerance test than women with low or normal waist/hip ratio. Men with high waist/hip ratio had higher tPA antigen, glucose and insulin responses to an oral glucose tolerance test than men with low or normal waist/hip ratio. In two dietary studies different low-energy diets (a juice fast or a weight reduction program) were followed. PAI-1 activity was decreased in both cases. In a third dietary study, transition from a high-fat/low-carbohydrate diet to a low-fat/high-carbohydrate diet decreased PAI-1 activity provided that it did not also cause a substantial increase in triglycerides or glucose. In a fourth dietary study the regular diet was supplemented with oat-husk. PAI-1 activity was reduced; a small increase in glucose but not in triglyceride levels was observed. On the basis of these results it is concluded that PAI-1 activity levels are associated with constitutional factors such as body mass index and waist/hip ratio. PAI-1 is elevated in obesity. Nutritional factors are also of importance for the PAI-1 activity levels. PAI-1 activity levels can be reduced by dietary regiments such as low-energy diets or high-fiber diets.

Diss. (sammanfattning) Umeå : Umeå universitet, 1993, härtill 6 uppsatser.


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