Academic literature on the topic 'Foreign economic activity regulation'

Relevance of research topic. In conditions of the high-level export-oriented national economy of Ukraine, the importance of foreign trade and monetary policy research including the development of currency regulation becomes especially relevant. The need for a system of currency regulation based on the principles of liberalization, which corresponds to both the general economic situation in Ukraine and global trends, requires special attention to studying the instruments of currency regulation. Analysis of recent research and publications. Among the most studied aspects of regulating currency relations should be noted: the theoretical fundamentals of international monetary and financial relations, state regulation of the economy, international regulation of monetary relations, liberalization of international monetary relations, the current state and prospects of development of currency regulation in Ukraine and the monetary and financial mechanism of foreign economic activity. Selection of unexplored parts of the general problem. Due to the global challenges and the constant evolution of monetary and financial relations, as well as the modernization of the system of currency regulation in Ukraine, the peculiarities of formation and application of the instruments of currency regulation of foreign economic activity require a more detailed study. Setting the task, the purpose of the study. To analyze the modern instruments of currency regulation of foreign economic activity and the peculiarities of their use in Ukraine. Method or methodology for conducting research. System and structural approach, method of logical analysis, statistical method, method of graphic analysis, method of comparison, method of structuring. Presentation of the main material (results of work). The paper describes approaches to the definition of currency regulation of foreign economic activity. Its place in the economic system of the state is considered. The system of instruments and levers of currency regulation of foreign economic activity is proposed based on direct and indirect regulation. The use of instruments of currency regulation of foreign economic activity in Ukraine in the modern conditions of currency regulation system liberalization is characterized. The field of application of results. Educational process (in the preparation of the relevant sections of textbooks and tutorials for courses “International Economics”, “Global Economics”, “Finance”). Conclusions according to the article. Analysis of the essence and approaches to the definition of currency regulation of foreign economic activity allows considering it as an instrument of currency policy and an integral part of foreign economic policy, state regulation of the economy, financial regulation of foreign economic activity. Indirect and direct currency regulations define its regulatory and control functions. Thereafter the exchange rate and currency transactions should be considered as the main instruments of currency regulation of foreign economic activity. The corresponding regulation levers are triggering the instruments of currency regulation of foreign economic activity. The levers of currency transactions instrument are rules of trade in currency values, currency restrictions, rules of administrating the foreign exchange proceeds of business entities. The levers of the exchange rate instrument are exchange rate regimes, devaluation/revaluation, foreign exchange interventions, foreign exchange reserves diversification. A new currency regulation system that provides the significant liberalization of currency transactions and capital movements was launched in Ukraine in 2019. According to it the concept of foreign exchange control as a repressive mechanism will be removed from the legislation, and a system of currency supervision will be introduced instead. The priority of less discriminatory instruments of currency regulation is also defined. Thus, it can be argued that the considered instruments of currency regulation of foreign economic activity reflect the trends of Ukraine's integration into the world financial and economic system.

Relevance of research topic. One of the features of foreign economic activity is vulnerability because of fluctuations of the global market environment, which requires the use of mechanisms for its regulation using financial instruments, methods and leverage. Formulation of the problem. Effective regulation of foreign economic activity, which would correspond to its actual goals and objectives, requires the formation of financial regulatory levers system. Analysis of recent research and publications. The issues of financial mechanism and financial regulation functioning today are the subject of detailed research in the professional scientific literature on finance. Scientific interest is also caused by studies of modern financial regulatory mechanisms in various areas of the national economy, in particular, regulation in the sphere of foreign economic activity. Selection of unexplored parts of the general problem. Nowadays there is no consensus on the essence of financial leverage, its features and place in the structure of the financial mechanism. There is a lack of research on the problems of using financial levers within the framework of the mechanism for regulating foreign economic activity. Setting the task, the purpose of the study. Classification of financial levers of foreign economic activity regulation and specification of their composition as to methods and instruments of regulation. Method or methodology for conducting research. The system and structural approach, the method of logical analysis, the method of comparison were used. Presentation of the main material (results of work). In the paper the importance of applying financial levers in foreign economic activity regulation is grounded. Based on the essence of financial regulation, the structure of the financial mechanism, the goals and composition of the system of foreign economic activity financial regulation, the classification of financial levers for its regulation has been proposed. Directions of financial levers actions, forms of levers implementation, methods of regulation, and levels of regulation are highlighted as classification signs. In the framework of the proposed classification by regulation methods, a set of financial levers is presented in relation to the corresponding methods and instruments for foreign economic activity regulation. The field of application of results. Research of foreign economic activity financial regulation problems, educational process (in the preparation of the relevant sections of textbooks and tutorials for courses “Finance”, “Foreign Trade”). Conclusions according to the article. The specific features of financial levers of foreign economic activity regulation are their multi-level influence on it, orientation at obtaining strengthening or retaining effect in accordance with the goals the state sets in the sphere of foreign economic activity regulation. Each lever is used within the relevant regulatory instruments and putting them in motion, and is aimed at the implementation of the regulatory action. Financial levers of regulation are interconnected into a single system and should be used comprehensively in foreign economic activity regulation.

Relevance of research topic. In modern conditions of globalization and strengthening the international integration processes, the enterprises foreign economic activity (FEA) acquires strategic importance for their further development. Formulation of the problem. Today, one of the problems facing business entities in their foreign economic activity is the lack of an effective mechanism for its financial regulation. Taking into account the leading role of financial and economic factors in the management of the foreign economic activity, such a mechanism would allow enterprises to implement effectively their foreign economic strategy and improve their competitive positions in the foreign markets. Analysis of recent research and publications. The problems of financial mechanisms and financial regulation are the subject of research in the professional scientific literature on the theory of finance. Certain issues related to the financial regulation of enterprises’ foreign economic activity are studied in scientific papers on foreign economic activity, financial management, foreign economic activity management, strategic management of the foreign economic activity. Selection of unexplored parts of the general problem. A thorough study must be conducted on the specifics of financial regulation of foreign economic activity at the level of business entities, as well as on the creation and functioning of a financial self-regulation mechanism in foreign economic activity. Setting the task, the purpose of the study. Developing a mechanism of financial regulation of business entities foreign economic activity, and studying its components, taking into account the peculiarities of financial regulation of foreign economic activity at the micro-level. Method or methodology for conducting research. System and structural approach, method of logical analysis, method of graphic analysis, method of comparison, method of structuring. Presentation of the main material (results of work). The paper substantiates the feasibility of creating a separate mechanism on the enterprises carrying out foreign economic activity, aimed at its financial regulation. Based on the analysis of the domestic legal framework and scientific research on foreign economic activity and enterprise finances, the features of financial regulation of business entities foreign economic activity are determined, which should be taken into account when building an appropriate mechanism. The mechanism of financial regulation of business entities foreign economic activity is developed and its components are investigated. The field of application of results. Scientific research of the problems of financial regulation of business entities foreign economic activity, the educational process (in the preparation of the relevant sections of textbooks and tutorials for courses "Finance", "Foreign economic activity"). Conclusions according to the article. When forming the mechanism of financial regulation of business entities foreign economic activity, the peculiarities of such a regulation at the business entities level should be taken into account. The structure of the mechanism of financial regulation of business entities foreign economic activity is built based on its belonging to the general mechanism of enterprise management, the mechanism of foreign economic activity management, the financial mechanism of enterprises, and the monetary-financial mechanism of foreign economic activity. The structure includes financial management of business entity foreign economic activity as a set of target, functional, providing, and management subsystems, as well as a subsystem of financial levers through which the influences on foreign economic activity are made, and a direct regulation subsystem. Along with the key role of state regulation, the enterprises’ managers must make and implement independent decisions, develop their own systems of financial regulation of foreign economic activity at the corporate level.

The article discusses the theoretical and methodological foundations of the study of integration processes and their practical testing. One of the most important areas for im-proving the efficiency of production and the country's economy is the development of foreign eco-nomic activity in the region. The activities of the foreign trade operations on the regional level implies economic benefits in the future. Establishing international business relations is necessary in order to increase the volume of exports, and as a result, companies receive more profit. State participation in the development of foreign economic activity in the region is to create favorable conditions for its development at the national (system of support and regulation of foreign eco-nomic activity) and interstate (in the framework of cooperation with foreign countries and partic-ipation in international organizations and forums) levels.

The paper assesses the fact that in the current conditions of globalization, any national economy is becoming more open, and therefore the state should take into account in its trade and economic policy the consistent relationship between the processes occurring within the economy and in the sphere of foreign economic relations. The state also acts as the organizer of the system of servicing foreign economic relations and achieving internal economic equilibrium, and finances this activity from budgetary funds. This system is branched in its nature, covering such areas of activity as the provision of information and consulting services, and organization of advertising and exhibition work; it also helps to increase the efficiency of foreign economic activity, introducing new participants to it. The authors conclude that in order to maintain domestic economic balance, the state should strengthen its influence on imports in order to maintain domestic producers and without depriving them of competition from foreign goods at the same time.

The article examines the definition of the term "foreign economic activity", analyses the definitions of foreign economic activity as well as legislation and theory formed in connection with the emergence, as well as the history of this term. Based on the results of the analysis of the definition of the term "foreign economic activity", its advantages and fragmentation and incompleteness are formulated in separate definitions, the need to highlight its complexity and multi-segment is emphasized, which are the objects, criteria and analytical features of economic management at micro level and legal regulation at macro level in this area. The article revealed the composition of the elements of the system of legal regulation of foreign economic activity, which includes: types of foreign economic activity, methods of foreign economic regulation, tools to influence foreign economic activity, subjects of foreign economic activity in Ukraine. The non-exclusive importance of legal regulation of foreign economic activity of economic entities in the field of grain growing is substantiated, namely the strategic importance of grain in the process of ensuring economic security of the country, including food, the priority of the grain market, which is enshrined in law. Based on the analysis of the system of legal regulation of foreign economic activity, a systematic approach to the interpretation of the category "legal regulation of foreign economic activity in the field of grain growing" is proposed. Improvement and specification of the specific category in the field of grain growing will create the necessary conditions for increasing the efficiency of using the existing potential at macro and micro levels. The proposals were made to improve the current legislation by eliminating the identified shortcomings in the definition of the term category in the interpretation of the concept of "foreign economic activity", what will promote the development of the system of legal regulation of foreign economic activity in the field and achieving the goals of sustainable development of Ukraine in accordance with the National Report of the Ministry of Economic Development and Trade of Ukraine (2017), in particular, the legal regulation of investment insurance.

Економічні перетворення в умовах кризи і процеси інтеграції що відбуваються у всьому світі, не залишають шансів будь-якій країні шукати і встановлювати свої власні, національні правила митного регулювання, внаслідок чого формується нова філософія митного регулювання. Сьогодні можна з повною упевненістю говорити про появу принципово нового підходу до митного регулювання, що враховує підприємницькі інтереси учасників зовнішньоекономічної діяльності. При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/33991

В даній магістерській кваліфікаційній роботі обґрунтовано актуальність теми, її значущість, визначено об’єкт та предмет дослідження, перелік використаних методів дослідження, а також розкрито теоретичні, методичні та фінансові основи державного регулювання фінансових аспектів зовнішньоекономічної діяльності на прикладі ТОВ «ХЕКСА». Актуальність теми роботи зумовлена потребою удосконалення аспектів зовнішньоекономічної збутової діяльності як одного із найважливіших напрямків покращення фінансового стану підприємства та економічного зростання загалом. Метою написання магістерської кваліфікаційної дипломної роботи є дослідження теоретико-методичних положень та розроблення практичних рекомендацій з удосконалення аспектів зовнішньоекономічної збутової діяльності на прикладі ТОВ «ХЕКСА». Для дослідження цієї мети в роботі вирішено такі основні завдання: - узагальнено теоретичні підходи до визначення сутності зовнішньоекономічної діяльності, згрупровано фактори впливу на ефективність зовнішньоекономічної збутової діяльності; - представлено характеристику особливостей діяльності ТОВ «ХЕКСА» та здійснено аналіз його фінансового стану; - досліджено сильні і слабкі сторони, а також можливості і загрози щодо розвитку зовнішньекономічної збутової діяльності ТОВ «ХЕКСА»; - розроблено пропозиції щодо управління ціновою пропозицією ТОВ «ХЕКСА» на основі точки беззбитковості для освновних експортних позицій ТОВ «ХЕКСА»; - сформовано складові алгоритму хеджування валютного ризику для ТОВ «ХЕКСА» в процесі здійснення зовнішньоекономічної діяльнсоті; - визначено вплив реалізації запропонованих заходів на результати фінансово-економічної діяльності ТОВ «ХЕКСА».
In this master's qualification work, the relevance of the topic, its significance, the object and subject of the research, the list of research methods used, as well as theoretical, methodical and financial bases of state regulation of financial aspects of foreign economic activity on the example of Hexa LLC are substantiated. The relevance of the topic of work is due to the need to improve aspects of foreign economic activity as one of the most important areas for improving the financial condition of the enterprise and economic growth in general. The purpose of writing a master's qualification diploma thesis is to study theoretical and methodological provisions and to develop practical recommendations for improving aspects of foreign trade marketing activity on the example of Hexa LLC. In order to investigate this goal, the following main tasks are solved in the work: - generalized theoretical approaches to determining the nature of foreign economic activity, grouped the factors of influence on the effectiveness of foreign economic sales activity; - the characteristics of the activities of Hexa LLC are presented and its financial status is analyzed; - Strengths, weaknesses, opportunities and threats to the development of foreign economic activity of Hexa LLC were investigated; - proposals for managing the price offer of Hexa LLC based on the break-even point for the main export positions of Hexa LLC were developed; - the components of the currency risk hedging algorithm for Hexa LLC in the process of foreign economic activity are formed; - the impact of the implementation of the proposed measures on the results of financial and economic activities of Hexa LLC has been determined.

В роботі розглянуто сутність та складові митного регулювання, розкриваються основні аспекти митного контролю та напрямки забезпечення його ефективності.
The paper considers the nature and components of customs regulations, reveals the main aspects of customs control and direction of ensuring its effectiveness.

У роботі досліджено теоретичні та методологічні засади та розробка практичних рекомендацій щодо вдосконалення системи зовнішньоекономічної діяльності підприємства. Цілі та основні принципи зовнішньоекономічної діяльності підприємства.
The theoretical and methodological principles and develop practical recommendations for improving the system of foreign economic activity of the enterprise. The objectives and basic principles of foreign economic activity of the enterprise.

Germany’s economic dominance in Europe, generous investment incentives, and technical manufacturing prowess has encouraged an influx of Chinese-led inbound activity, concentrated in high-tech sector mergers and acquisitions. A close examination of these M&As yields evidence of systemic Chinese state-financing through both state-owned and private vehicles that likely stems from China’s “Made in China 2025” policy, which hopes to stem capital outflow and to indigenize technological innovation. As Germany braces for what it sees to be continuous attempts by China to take patented German technology through M&As, it worries that Chinese patent law will allow for rampant patent infringement by copycat Chinese entities. This paper presents an overview of the root causes of China’s heavy economic activity in Germany, as well as an analysis of the legal concerns held by German firms based on a close reading of the Patent Law of the People’s Republic of China and strategic recommendations for German companies hoping to work with or in China.

Офшорна фінансова діяльність посідає значне місце у глобальній фінансовій системі, спостерігається суттєве зростання обсягів офшорних операцій та зростання кількості офшорних фінансових установ. Зважаючи на широке використання офшорів вітчизняними підприємцями та значні масштаби відтоку капіталу з економіки України в офшорні зони, дослідження негативного впливу офшорів на національну економіку та знаходження шляхів вирішення даної проблеми на сьогоднішній день є особливо актуальними. У роботі надана характеристика теоретичних засад офшорних зон, розглянуті принципи, покладені в його основу, даються різні класифікації офшорних зон, їх функціональне призначення. Описані цілі створення офшорних зон його переваги та недоліки. Розглянуті особливості функціонування офшорних юрисдикцій в сучасних умовах. Надані основні напрямки протидії негативним наслідкам діяльності офшорних юрисдикцій, наведені проблеми функціонування офшорного бізнесу і можливі шляхи їх вирішення.
The object of study of the master's thesis is the mechanism of functioning of offshore zones, the subject - financial relations that arise in the process of financial and economic activities of offshore zones and their impact on the economy. The methodological basis of the work is a systematic approach and a dialectical method. In addition, the methods of unity of historical and logical, comparative analysis, induction and deduction, as well as positive and normative approaches were used in the work. Results: the essence of the concept and history of offshore zones development is considered, the specifics of separate offshore zones and their characteristics and specialization are studied, advantages of doing business in offshore zones are allocated, the problems connected with capital migration to offshore zones are opened, problems of offshorization and deoffshorization of domestic business. The theoretical significance of the master's thesis is to justify the need to regulate national legislation on the deoffshorization of business in the country. The practical significance of the work lies in the generalization and systematization of a large array of statistical data, recommendations and proposals of scientists, specialists dealing with the problem of offshorization and deoffshorization in modern conditions. In the near future, the role of offshore zones in the world economy will weaken as more countries join the organization to combat further offshorization of business through various agreements.

Дисертація на здобуття наукового ступеня доктора економічних наук за спеціальністю 08.00.01 – економічна теорія та історія економічної думки. – Державний вищий навчальний заклад “Національний гірничий університет”. – Дніпропетровськ, 2013.
Диссертация на соискание ученой степени доктора экономических наук по специальности 08.00.01 – экономическая теория и история экономической мысли. – Государственное высшее учебное заведение “Национальный горный университет”. – Днепропетровск, 2013
Dissertation for a Doctor Degree in Economics. Specialty 08.00.01 – Economic Theory and History of Economic Thought. – State Higher educational Establishment “National Mining University”. – Dnipropetrovsk, 2013
Проведений аналіз відмітних рис ринкової координації. У дисертації вводиться новий методологічний принцип індивідуалістичного релятивізму. Досліджена роль суб’єктних та позасуб’єктних оцінок у процесі діадичної міжсуб’єктної взаємодії. Проаналізовані два підходи до інтерпретації мети та припустимих меж конкуренції. Досліджені особливості суб’єктного оцінювання на ринку кінцевих благ. Розроблена модель ринку кінцевих благ, розділеного на цінові категорії. Розглянуті передумови стійкості цінових категорій. Досліджений механізм впливу продавця на свідомість покупця за рахунок зміни референтної точки та поля вибору. Розглянутий процес розподілу спільно створеного продукту між учасниками виробництва. Проаналізована роль суб’єктних та позасуб’єктних оцінок у розподілі спільно створеного продукту. Досліджений процес інституціоналізації оцінок. Запропонована модель ринку праці, яка включає суб’єктне оцінювання. Аналізуються проблеми відтворювально-ефективного розподілу спільно створеного продукту. Встановлені принципи ефективного комбінування ринкового саморегулювання та державної політики з метою забезпечення сталого розвитку. Розроблені концептуальні моделі реформи пенсійного забезпечення та реформи регулювання зовнішньоекономічної діяльності
Проведен анализ отличительных черт рыночной координации. Исследована терминологическая нестрогость содержания категорий “рынок” и “рыночное”. Выявлена возможность исследования рыночной координации на уровне диадического межсубъектного взаимодействия. В диссертации вводится новый методологический принцип индивидуалистического релятивизма, включающий внутренне-компаративное и внешне-компаративное субъектное оценивание. Исследована роль субъектных и внесубъектних оценок в процессе диадического межсубъектного взаимодействия. Проанализированы эгоистический и интегративный подходы к интерпретации целей и допустимых пределов конкуренции. Исследованы особенности субъектного оценивания на рынке конечных благ. Разработана модель рынка конечных благ, разделенного на ценовые категории, включающая субъектные оценки покупателей и продавцов. Рассмотрены предпосылки устойчивости ценовых категорий с учетом различной ценовой эластичности спроса для разных ценовых категорий. Исследован механизм влияния продавца на сознание покупателя за счет изменения точки сравнения и поля выбора. Выявлено, что в условиях среды, контролируемой продавцом, покупатель утрачивает суверенитет при совершении покупок. Рассмотрен процесс распределения совместно созданного продукта между участниками производства. Проанализирована роль субъектных и внесубъектных оценок в распределении совместно созданного продукта. Выявлены угрозы нарушения паритета в отношениях между участниками совместного производственного процесса и появления перераспределительной власти за счёт манипулирования субъектными оценками контрагента. Исследован процесс институционализации оценок, предполагающий игнорирование промежуточных причинно-следственных связей при оценивании предметов или явлений. Предложена модель рынка труда, которая включает субъектное оценивание работником возможных последствий прекращения контракта с работодателем. Выявлены объективные предпосылки смещения экономической власти во взаимодействиях типа “работник – работодатель” в пользу работодателя с последующей гиперэксплуатацией наиболее квалифицированной части рабочей силы. Анализируются проблемы воспроизводственно-эффективного распределения совместно созданного продукта применительно к воспроизводству рабочей силы. Изложена концепция пенсионной реформы, учитывающая участие пенсионера в воспроизводстве будущих поколений и учитывающая специфику субъектного оценивания. Выявлена специфика концентрации политической власти в условиях манипулирования субъектными оценками участников политического процесса. Установлены принципы эффективного комбинирования рыночного саморегулирования и государственной политики с целью обеспечения устойчивого развития. Разработана концептуальная модель реформы регулирования внешнеэкономической деятельности, включающей аукционную продажу квот на вывод иностранной валюты за пределы Украины. Проанализированы возможности этой реформы по регулированию платёжного баланса и предотвращению кризисов, вызванных валютными шоками
The analysis of the characteristic features of market coordination is carried out. A new methodological principle of individualistic relativism is introduced in the paper. The role of subject and out-of-subject estimations in the process of dyadic interaction between subjects is studied. Two approaches to the interpretation of the purpose and permissible levels of competition are distinguished. Peculiarities of subject estimations on the market of final goods are investigated. The model of market divided into price categories is suggested. Preconditions of price categories sustainability are reviewed. The mechanism of sellers’ impact on the minds of customer by changing the reference point and field of selection is investigated. The process of sharing of common product between participants of production is considered. The role of subject and out-of subject estimations in product distribution is examined. The process of estimations’ institutionalization is reviewed. The model of labour market regarding subject estimations is suggested. Problems of reproductive efficiency of common product distribution are analyzed. Principles of effective combining of market self-regulation and public policy to ensure sustainable development are discussed. Conceptual models of pension reform and foreign economic activity regulation reform are worked out.

The textbook deals with the problems of conducting foreign economic activity from the point of view of taxation, accounting, analysis, audit, application of Russian and international legislation regulating this type of activity. All theoretical provisions are analyzed on the example of practical situations that arise in real practice. The presented theoretical material and practical situations are designed to help master the conduct of foreign economic activity. The textbook contains diagrams, tables of typical operations, sample documents, verification tests on each topic, practical tasks and applications of the necessary documents for a more complete development of the discipline. Meets the requirements of the federal state educational standards of higher education of the latest generation. For bachelors, undergraduates, postgraduates studying in economic programs and studying foreign economic activity in depth, the textbook will also be useful for teachers of economic faculties of universities and practitioners.

The monograph comprehensively examines the models and experience of interaction between government and business of the leading modern economic systems. Close attention is paid to the Russian specifics of relations between the state and the business community, starting with the characteristics of the institutional foundations and changing business conditions in Russia and ending with the problem of trust. Such aspects of the relationship as the leading role of the state in economic management, inconsistency of legislative regulation of entrepreneurial activity, excessive fiscal administration and tax burden, insufficient level of professionalism of personnel, social responsibility of business are disclosed. The empirical basis of the monograph is a study that was carried out within the framework of the RFBR grant "New models of interaction between the government and the industrial community in conditions of increasing risks of technological development under the influence of international sanctions". It is addressed to researchers and university teachers, graduate students and students specializing in the field of business relations and public authorities, as well as related fields of scientific research.

The COP9 signalosome (CSN) is an eight-subunit protein complex that is highly conserved among eukaryotes. Genetic analysis of the signalosome in the plant model species Arabidopsis thaliana has shown that the signalosome is a repressor of light dependent seedling development as mutant Arabidopsis seedlings that lack this complex develop in complete darkness as if exposed to light. These mutant plants die following the seedling stage, even when exposed to light, indicating that the COP9 signalosome also has a central role in the regulation of normal photomorphogenic development. The biochemical mode of action of the signalosome and its position in eukaryotic cell signaling pathways is a matter of controversy and ongoing investigation, and recent results place the CSN at the juncture of kinase signaling pathways and ubiquitin-mediated protein degradation. We have shown that one of the many CSN functions may relate to the regulation of translation through the interaction of the CSN with its related complex, eukaryotic initiation factor (eIF3). While we have established a physical connection between eIF3 subunits and CSN subunits, the physiological and developmental significance of this interaction is still unknown. In an effort to understand the biochemical activity of the signalosome, and its role in regulating translation, we originally proposed to dissect the contribution of "h" subunit of eIF3 (eIF3h) along the following specific aims: (i) Isolation and phenotypic characterization of an Arabidopsis loss-of-function allele for eIF3h from insertional mutagenesis libraries; (ii) Creation of designed gain and loss of function alleles for eIF3h on the basis of its nucleocytoplasmic distribution and its yeast-two-hybrid interactions with other eIF3 and signalosome partner proteins; (iii) Determining the contribution of eIF3h and its interaction with the signalosome by expressing specific mutants of eIF3h in the eIF3h- loss-of function background. During the course of the research, these goals were modified to include examining the genetic interaction between csn and eif3h mutations. More importantly, we extended our effort toward the genetic analysis of mutations in the eIF3e subunit, which also interacts with the CSN. Through the course of this research program we have made several critical scientific discoveries, all concerned with the apparent diametrically opposed roles of eIF3h and eIF3e. We showed that: 1) While eIF3e is essential for growth and development, eIF3h is not essential for growth or basal translation; 2) While eIF3e has a negative role in translational regulation, eIF3h is positively required for efficient translation of transcripts with complex 5' UTR sequences; 3) Over-accumulation of eIF3e and loss-of-function of eIF3h both lead to cop phenotypes in dark-grown seedlings. These results were published in one publication (Kim et al., Plant Cell 2004) and in a second manuscript currently in revision for Embo J. Are results have led to a paradigm shift in translation research – eIF3 is now viewed in all systems as a dynamic entity that contains regulatory subuits that affect translational efficiency. In the long-term agronomic outlook, the proposed research has implications that may be far reaching. Many important plant processes, including developmental and physiological responses to light, abiotic stress, photosynthate, and hormones operate in part by modulating protein translation [23, 24, 40, 75]. Translational regulation is slowly coming of age as a mechanism for regulating foreign gene expression in plants, beginning with translational enhancers [84, 85] and more recently, coordinating the expression of multiple transgenes using internal ribosome entry sites. Our contribution to understanding the molecular mode of action of a protein complex as fundamental as eIF3 is likely to lead to advances that will be applicable in the foreseeable future.

D. Ricardo is one of the founders of classical economy. The most significant discoveries of the outstanding scientist in the field of capital can be called the definition of capital and free capital, the creation of a theory of comparative advantages of trade, the division of capital into fixed and circulating capital depending on strength, as well as the description of the reasons that stimulate and hinder foreign investment. Given that capital is primarily an economic category, it seems quite reasonable to consider the emergence and development of these concepts in the retrospect of economic theories, in order to understand the essence of the phenomenon and finally solve the issue of its legal regulation.

Original objectives: The basic goal of the present project was to increase our understanding of the cellular mechanisms operating during the gravitropic response of cut flowers, for solving their bending problem without affecting flower quality. Thus, several elements operating at the 3 levels o the gravity-induced signal transduction pathway, were proposed to be examined in snapdragon stems according to the following research goals: 1) Signaling: characterize the signal transduction pathway leading to the gravitropic response, regarding the involvement of [Ca2+]cyt as a mediator of IAA movement and sensitivity to auxin. 2) Transduction by plant hormones: a) Examine the involvement of auxin in the gravitropic response of flower stems with regard to: possible participation of auxin binding protein (ABP), auxin redistribution, auxin mechanism of action (activation of H+-ATPase) mediation by changes in [Ca2+]cyt and possible regulation of auxin-induced Ca2+ action b: calmodulin-activated or Ca2+-activated protein kinases (PK). b) Examine the involvement of ethylene in the gravitropic response of flower stems with regard to auxin-induced ethylene production and sensitivity of the tissue to ethylene. 3) Response: examine the effect of gravistimulation on invertase (associated with growth and elongation) activity and invertase gene expression. 4) Commercial practice: develop practical and simple treatments to prevent bending of cut flowers grown for export. Revisions: 1) Model systems: in addition to snapdragon (Antirrhinum majus L.), 3 other model shoe systems, consisting of oat (Avena sativa) pulvini, Ornithogalun 'Nova' cut flowers and Arabidopsis thaliana inflorescence, were targeted to confirm a more general mechanism for shoot gravitropism. 2 Research topics: the involvement of ABP, auxin action, PK and invertase in the gravitropic response of snapdragon stems could not be demonstrated. Alternatively, the involvement in the gravity signaling cascade of several other physiological mediators apart of [Ca2+]cyt such as: IP3, protein phosphorylation and actin cytoskeleton, was shown. Additional topics introduced: starch statolith reorientation, differential expression of early auxin responsive genes, and differential shoot growth. Background to the topic: The gravitropic bending response of flowering shoots occurring upon their horizontal placement during shipment exhibits a major horticultural problem. In spite of extensive studies in various aboveground organs, the gravitropic response was hardly investigated in flowering shoots. Being a complex multistep process that requires the participation of various cellular components acting in succession or in parallel, analysis of the negative gravitropic response of shoot includes investigation of signal transduction elements and various regulatory physiological mediators. Major achievements: 1) A correlative role for starch statoliths as gravireceptors in flowering shoot was initially established. 2) Differentially phosphorylated proteins and IP3 levels across the oat shoe pulvini, as well as a differential appearance of 2 early auxin-responsive genes in snapdragon stems were all detected within 5-30 minutes following gravistimulation. 3) Unlike in roots, involvement of actin cytoskeleton in early events of the gravitropic response of snapdragon shoots was established. 4) An asymmetric IAA distribution, followed by an asymmetric ethylene production across snapdragon stems was found following gravistimulation. 5) The gravity-induced differential growth in shoots of snapdragon was derived from initial shrinkage of the upper stem side and a subsequent elongation o the lower stem side. 6) Shoot bending could be successfully inhibited by Ca2+ antagonists (that serve as a basis for practical treatments), kinase and phosphatase inhibitors and actin-cytoskeleton modulators. All these agents did not affect vertical growth. The essential characterization of these key events and their sequence led us to the conclusion that blocking gravity perception may be the most powerful means to inhibit bending without hampering shoot and flower growth after harvest. Implications, scientific and agriculture: The innovative results of this project have provided some new insight in the basic understanding of gravitropism in flower stalks, that partially filled the gap in our knowledge, and established useful means for its control. Additionally, our analysis has advanced the understanding of important and fundamental physiological processes involved, thereby leading to new ideas for agriculture. Gravitropism has an important impact on agriculture, particularly for controlling the bending of various important agricultural products with economic value. So far, no safe control of the undesired bending problem of flower stalks has been established. Our results show for the first time that shoot bending of cut flowers can be inhibited without adverse effects by controlling the gravity perception step with Ca2+ antagonists and cytoskeleton modulators. Such a practical benefit resulting from this project is of great economic value for the floriculture industry.

The article examines the views of one of the founders of classical economics, David Ricardo, on the issues of investment, capital and profit. The need for this study is caused by the lack of a single definition of investment in the regulatory acts of investment legislation, as well as in the scientific community. Thus, there is a problem of regulatory regulation of one of the most important concepts of the economy. Given that the concepts of investment, capital, and capital investment are primarily economic categories, it seems quite reasonable to consider the emergence and development of these concepts in the retrospect of economic theories, in order to understand the essence of the phenomenon and finally solve the issue of its legal regulation. The scientific novelty of the study is that despite a large number of works on the work of David Ricardo «The Beginnings of Political Economy and Taxation», no special work was carried out on the contribution of the great economist to the theory of investment. Conclusions. The main achievements of Ricardo in the field of capital and investment include the author's definitions of capital, free capital, the creation of a theory of comparative advantages of trade, the division of capital into fixed and circulating capital depending on strength, as well as the description of the reasons that stimulate and hinder foreign investment.

Effective development of the domestic economy is possible only on condition of mandatory formation of a qualitatively new level of regulation of economic relations in the business environment. By its nature, entrepreneurship is an activity associated with a high level of risk and innovation, aimed at ensuring the interests of both an individual entrepreneur and an enterprise, and society. The purpose of the study, the results of which are presented in this article, is to study theoretical and methodological approaches to managing financial risks of an enterprise in modern dynamically changing conditions.

1.1 Macroeconomic summary Economic recovery has consistently outperformed the technical staff’s expectations following a steep decline in activity in the second quarter of 2020. At the same time, total and core inflation rates have fallen and remain at low levels, suggesting that a significant element of the reactivation of Colombia’s economy has been related to recovery in potential GDP. This would support the technical staff’s diagnosis of weak aggregate demand and ample excess capacity. The most recently available data on 2020 growth suggests a contraction in economic activity of 6.8%, lower than estimates from January’s Monetary Policy Report (-7.2%). High-frequency indicators suggest that economic performance was significantly more dynamic than expected in January, despite mobility restrictions and quarantine measures. This has also come amid declines in total and core inflation, the latter of which was below January projections if controlling for certain relative price changes. This suggests that the unexpected strength of recent growth contains elements of demand, and that excess capacity, while significant, could be lower than previously estimated. Nevertheless, uncertainty over the measurement of excess capacity continues to be unusually high and marked both by variations in the way different economic sectors and spending components have been affected by the pandemic, and by uneven price behavior. The size of excess capacity, and in particular the evolution of the pandemic in forthcoming quarters, constitute substantial risks to the macroeconomic forecast presented in this report. Despite the unexpected strength of the recovery, the technical staff continues to project ample excess capacity that is expected to remain on the forecast horizon, alongside core inflation that will likely remain below the target. Domestic demand remains below 2019 levels amid unusually significant uncertainty over the size of excess capacity in the economy. High national unemployment (14.6% for February 2021) reflects a loose labor market, while observed total and core inflation continue to be below 2%. Inflationary pressures from the exchange rate are expected to continue to be low, with relatively little pass-through on inflation. This would be compatible with a negative output gap. Excess productive capacity and the expectation of core inflation below the 3% target on the forecast horizon provide a basis for an expansive monetary policy posture. The technical staff’s assessment of certain shocks and their expected effects on the economy, as well as the presence of several sources of uncertainty and related assumptions about their potential macroeconomic impacts, remain a feature of this report. The coronavirus pandemic, in particular, continues to affect the public health environment, and the reopening of Colombia’s economy remains incomplete. The technical staff’s assessment is that the COVID-19 shock has affected both aggregate demand and supply, but that the impact on demand has been deeper and more persistent. Given this persistence, the central forecast accounts for a gradual tightening of the output gap in the absence of new waves of contagion, and as vaccination campaigns progress. The central forecast continues to include an expected increase of total and core inflation rates in the second quarter of 2021, alongside the lapse of the temporary price relief measures put in place in 2020. Additional COVID-19 outbreaks (of uncertain duration and intensity) represent a significant risk factor that could affect these projections. Additionally, the forecast continues to include an upward trend in sovereign risk premiums, reflected by higher levels of public debt that in the wake of the pandemic are likely to persist on the forecast horizon, even in the context of a fiscal adjustment. At the same time, the projection accounts for the shortterm effects on private domestic demand from a fiscal adjustment along the lines of the one currently being proposed by the national government. This would be compatible with a gradual recovery of private domestic demand in 2022. The size and characteristics of the fiscal adjustment that is ultimately implemented, as well as the corresponding market response, represent another source of forecast uncertainty. Newly available information offers evidence of the potential for significant changes to the macroeconomic scenario, though without altering the general diagnosis described above. The most recent data on inflation, growth, fiscal policy, and international financial conditions suggests a more dynamic economy than previously expected. However, a third wave of the pandemic has delayed the re-opening of Colombia’s economy and brought with it a deceleration in economic activity. Detailed descriptions of these considerations and subsequent changes to the macroeconomic forecast are presented below. The expected annual decline in GDP (-0.3%) in the first quarter of 2021 appears to have been less pronounced than projected in January (-4.8%). Partial closures in January to address a second wave of COVID-19 appear to have had a less significant negative impact on the economy than previously estimated. This is reflected in figures related to mobility, energy demand, industry and retail sales, foreign trade, commercial transactions from selected banks, and the national statistics agency’s (DANE) economic tracking indicator (ISE). Output is now expected to have declined annually in the first quarter by 0.3%. Private consumption likely continued to recover, registering levels somewhat above those from the previous year, while public consumption likely increased significantly. While a recovery in investment in both housing and in other buildings and structures is expected, overall investment levels in this case likely continued to be low, and gross fixed capital formation is expected to continue to show significant annual declines. Imports likely recovered to again outpace exports, though both are expected to register significant annual declines. Economic activity that outpaced projections, an increase in oil prices and other export products, and an expected increase in public spending this year account for the upward revision to the 2021 growth forecast (from 4.6% with a range between 2% and 6% in January, to 6.0% with a range between 3% and 7% in April). As a result, the output gap is expected to be smaller and to tighten more rapidly than projected in the previous report, though it is still expected to remain in negative territory on the forecast horizon. Wide forecast intervals reflect the fact that the future evolution of the COVID-19 pandemic remains a significant source of uncertainty on these projections. The delay in the recovery of economic activity as a result of the resurgence of COVID-19 in the first quarter appears to have been less significant than projected in the January report. The central forecast scenario expects this improved performance to continue in 2021 alongside increased consumer and business confidence. Low real interest rates and an active credit supply would also support this dynamic, and the overall conditions would be expected to spur a recovery in consumption and investment. Increased growth in public spending and public works based on the national government’s spending plan (Plan Financiero del Gobierno) are other factors to consider. Additionally, an expected recovery in global demand and higher projected prices for oil and coffee would further contribute to improved external revenues and would favor investment, in particular in the oil sector. Given the above, the technical staff’s 2021 growth forecast has been revised upward from 4.6% in January (range from 2% to 6%) to 6.0% in April (range from 3% to 7%). These projections account for the potential for the third wave of COVID-19 to have a larger and more persistent effect on the economy than the previous wave, while also supposing that there will not be any additional significant waves of the pandemic and that mobility restrictions will be relaxed as a result. Economic growth in 2022 is expected to be 3%, with a range between 1% and 5%. This figure would be lower than projected in the January report (3.6% with a range between 2% and 6%), due to a higher base of comparison given the upward revision to expected GDP in 2021. This forecast also takes into account the likely effects on private demand of a fiscal adjustment of the size currently being proposed by the national government, and which would come into effect in 2022. Excess in productive capacity is now expected to be lower than estimated in January but continues to be significant and affected by high levels of uncertainty, as reflected in the wide forecast intervals. The possibility of new waves of the virus (of uncertain intensity and duration) represents a significant downward risk to projected GDP growth, and is signaled by the lower limits of the ranges provided in this report. Inflation (1.51%) and inflation excluding food and regulated items (0.94%) declined in March compared to December, continuing below the 3% target. The decline in inflation in this period was below projections, explained in large part by unanticipated increases in the costs of certain foods (3.92%) and regulated items (1.52%). An increase in international food and shipping prices, increased foreign demand for beef, and specific upward pressures on perishable food supplies appear to explain a lower-than-expected deceleration in the consumer price index (CPI) for foods. An unexpected increase in regulated items prices came amid unanticipated increases in international fuel prices, on some utilities rates, and for regulated education prices. The decline in annual inflation excluding food and regulated items between December and March was in line with projections from January, though this included downward pressure from a significant reduction in telecommunications rates due to the imminent entry of a new operator. When controlling for the effects of this relative price change, inflation excluding food and regulated items exceeds levels forecast in the previous report. Within this indicator of core inflation, the CPI for goods (1.05%) accelerated due to a reversion of the effects of the VAT-free day in November, which was largely accounted for in February, and possibly by the transmission of a recent depreciation of the peso on domestic prices for certain items (electric and household appliances). For their part, services prices decelerated and showed the lowest rate of annual growth (0.89%) among the large consumer baskets in the CPI. Within the services basket, the annual change in rental prices continued to decline, while those services that continue to experience the most significant restrictions on returning to normal operations (tourism, cinemas, nightlife, etc.) continued to register significant price declines. As previously mentioned, telephone rates also fell significantly due to increased competition in the market. Total inflation is expected to continue to be affected by ample excesses in productive capacity for the remainder of 2021 and 2022, though less so than projected in January. As a result, convergence to the inflation target is now expected to be somewhat faster than estimated in the previous report, assuming the absence of significant additional outbreaks of COVID-19. The technical staff’s year-end inflation projections for 2021 and 2022 have increased, suggesting figures around 3% due largely to variation in food and regulated items prices. The projection for inflation excluding food and regulated items also increased, but remains below 3%. Price relief measures on indirect taxes implemented in 2020 are expected to lapse in the second quarter of 2021, generating a one-off effect on prices and temporarily affecting inflation excluding food and regulated items. However, indexation to low levels of past inflation, weak demand, and ample excess productive capacity are expected to keep core inflation below the target, near 2.3% at the end of 2021 (previously 2.1%). The reversion in 2021 of the effects of some price relief measures on utility rates from 2020 should lead to an increase in the CPI for regulated items in the second half of this year. Annual price changes are now expected to be higher than estimated in the January report due to an increased expected path for fuel prices and unanticipated increases in regulated education prices. The projection for the CPI for foods has increased compared to the previous report, taking into account certain factors that were not anticipated in January (a less favorable agricultural cycle, increased pressure from international prices, and transport costs). Given the above, year-end annual inflation for 2021 and 2022 is now expected to be 3% and 2.8%, respectively, which would be above projections from January (2.3% and 2,7%). For its part, expected inflation based on analyst surveys suggests year-end inflation in 2021 and 2022 of 2.8% and 3.1%, respectively. There remains significant uncertainty surrounding the inflation forecasts included in this report due to several factors: 1) the evolution of the pandemic; 2) the difficulty in evaluating the size and persistence of excess productive capacity; 3) the timing and manner in which price relief measures will lapse; and 4) the future behavior of food prices. Projected 2021 growth in foreign demand (4.4% to 5.2%) and the supposed average oil price (USD 53 to USD 61 per Brent benchmark barrel) were both revised upward. An increase in long-term international interest rates has been reflected in a depreciation of the peso and could result in relatively tighter external financial conditions for emerging market economies, including Colombia. Average growth among Colombia’s trade partners was greater than expected in the fourth quarter of 2020. This, together with a sizable fiscal stimulus approved in the United States and the onset of a massive global vaccination campaign, largely explains the projected increase in foreign demand growth in 2021. The resilience of the goods market in the face of global crisis and an expected normalization in international trade are additional factors. These considerations and the expected continuation of a gradual reduction of mobility restrictions abroad suggest that Colombia’s trade partners could grow on average by 5.2% in 2021 and around 3.4% in 2022. The improved prospects for global economic growth have led to an increase in current and expected oil prices. Production interruptions due to a heavy winter, reduced inventories, and increased supply restrictions instituted by producing countries have also contributed to the increase. Meanwhile, market forecasts and recent Federal Reserve pronouncements suggest that the benchmark interest rate in the U.S. will remain stable for the next two years. Nevertheless, a significant increase in public spending in the country has fostered expectations for greater growth and inflation, as well as increased uncertainty over the moment in which a normalization of monetary policy might begin. This has been reflected in an increase in long-term interest rates. In this context, emerging market economies in the region, including Colombia, have registered increases in sovereign risk premiums and long-term domestic interest rates, and a depreciation of local currencies against the dollar. Recent outbreaks of COVID-19 in several of these economies; limits on vaccine supply and the slow pace of immunization campaigns in some countries; a significant increase in public debt; and tensions between the United States and China, among other factors, all add to a high level of uncertainty surrounding interest rate spreads, external financing conditions, and the future performance of risk premiums. The impact that this environment could have on the exchange rate and on domestic financing conditions represent risks to the macroeconomic and monetary policy forecasts. Domestic financial conditions continue to favor recovery in economic activity. The transmission of reductions to the policy interest rate on credit rates has been significant. The banking portfolio continues to recover amid circumstances that have affected both the supply and demand for loans, and in which some credit risks have materialized. Preferential and ordinary commercial interest rates have fallen to a similar degree as the benchmark interest rate. As is generally the case, this transmission has come at a slower pace for consumer credit rates, and has been further delayed in the case of mortgage rates. Commercial credit levels stabilized above pre-pandemic levels in March, following an increase resulting from significant liquidity requirements for businesses in the second quarter of 2020. The consumer credit portfolio continued to recover and has now surpassed February 2020 levels, though overall growth in the portfolio remains low. At the same time, portfolio projections and default indicators have increased, and credit establishment earnings have come down. Despite this, credit disbursements continue to recover and solvency indicators remain well above regulatory minimums. 1.2 Monetary policy decision In its meetings in March and April the BDBR left the benchmark interest rate unchanged at 1.75%.

The UK government’s Integrated Review of security, defence, development and foreign policy, published in March 2021 alongside a supporting defence command paper, set a new course for UK national security and highlighted opportunities for an innovative approach to international engagement activity. The Integrated Review focused principally on the state threats posed by China’s increasing power and by competitors – including Russia – armed with nuclear, conventional and hybrid capabilities. It also stressed the continuing risks to global security and resilience due to conflict and instability in weakened and failed states. These threats have the potential to increase poverty and inequality, violent extremism, climate degradation and the forced displacement of people, while presenting authoritarian competitors with opportunities to enhance their geopolitical influence. There are moral, security and economic motives to foster durable peace in conflict-prone and weakened regions through a peacebuilding approach that promotes good governance, addresses the root causes of conflict and prevents violence, while denying opportunities to state competitors. The recent withdrawal from Afghanistan serves to emphasize the complexities and potential pitfalls associated with intervention operations in complex, unstable regions. Success in the future will require the full, sustained and coordinated integration of national, allied and regional levers of power underpinned by a sophisticated understanding of the operating environment. The UK armed forces, with their considerable resources and global network, will contribute to this effort through ‘persistent engagement’. This is a new approach to overseas operations below the threshold of conflict, designed as a pre-emptive complement to warfighting. To achieve this, the UK Ministry of Defence (MOD) must develop a capability that can operate effectively in weak, unstable and complex regions prone to violent conflict and crises, not least in the regions on the eastern and southern flanks of the Euro-Atlantic area. The first step must be the development of a cohort of military personnel with enhanced, tailored levels of knowledge, skills and experience. Engagement roles must be filled by operators with specialist knowledge, skills and experience forged beyond the mainstream discipline of combat and warfighting. Only then will individuals develop a genuinely sophisticated understanding of complex, politically driven and sensitive operating environments and be able to infuse the design and delivery of international activities with practical wisdom and insight. Engagement personnel need to be equipped with: An inherent understanding of the human and political dimensions of conflict, the underlying drivers such as inequality and scarcity, and the exacerbating factors such as climate change and migration; - A grounding in social sciences and conflict modelling in order to understand complex human terrain; - Regional expertise enabled by language skills, cultural intelligence and human networks; - Familiarity with a diverse range of partners, allies and local actors and their approaches; - Expertise in building partner capacity and applying defence capabilities to deliver stability and peace; - A grasp of emerging artificial intelligence technology as a tool to understand human terrain; - Reach and insight developed through ‘knowledge networks’ of external experts in academia, think-tanks and NGOs. Successful change will be dependent on strong and overt advocacy by the MOD’s senior leadership and a revised set of personnel policies and procedures for this cohort’s selection, education, training, career management, incentivization, sustainability and support.

The research on thermotolerance acquisition in broiler chickens by temperature conditioning early in life was focused on the following objectives: a. To determine the optimal timing and temperature for inducing the thermotolerance, conditioning processes and to define its duration during the first week of life in the broiler chick. b. To investigate the response of skeletal muscle tissue and the gastrointestinal tract to thermal conditioning. This objective was added during the research, to understand the mechanisms related to compensatory growth. c. To evaluate the effect of early thermo conditioning on thermoregulation (heat production and heat dissipation) during 3 phases: (1) conditioning, (2) compensatory growth, (3) heat challenge. d. To investigate how induction of improved thermotolerance impacts on metabolic fuel and the hormones regulating growth and metabolism. Recent decades have seen significant development in the genetic selection of the meat-type fowl (i.e., broiler chickens); leading to rapid growth and increased feed efficiency, providing the poultry industry with heavy chickens in relatively short growth periods. Such development necessitates parallel increases in the size of visceral systems such as the cardiovascular and the respiratory ones. However, inferior development of such major systems has led to a relatively low capability to balance energy expenditure under extreme conditions. Thus, acute exposure of chickens to extreme conditions (i.e., heat spells) has resulted in major economic losses. Birds are homeotherms, and as such, they are able to maintain their body temperature within a narrow range. To sustain thermal tolerance and avoid the deleterious consequences of thermal stresses, a direct response is elicited: the rapid thermal shock response - thermal conditioning. This technique of temperature conditioning takes advantage of the immaturity of the temperature regulation mechanism in young chicks during their first week of life. Development of this mechanism involves sympathetic neural activity, integration of thermal infom1ation in the hypothalamus, and buildup of the body-to-brain temperature difference, so that the potential for thermotolerance can be incorporated into the developing thermoregulation mechanisms. Thermal conditioning is a unique management tool, which most likely involves hypothalamic them1oregulatory threshold changes that enable chickens, within certain limits, to cope with acute exposure to unexpected hot spells. Short-tem1 exposure to heat stress during the first week of life (37.5+1°C; 70-80% rh; for 24 h at 3 days of age) resulted in growth retardation followed immediately by compensatory growth" which resulted in complete compensation for the loss of weight gain, so that the conditioned chickens achieved higher body weight than that of the controls at 42 days of age. The compensatory growth was partially explained by its dramatic positive effect on the proliferation of muscle satellite cells which are necessary for further muscle hypertrophy. By its significant effect of the morphology and functioning of the gastrointestinal tract during and after using thermal conditioning. The significant effect of thermal conditioning on the chicken thermoregulation was found to be associated with a reduction in heat production and evaporative heat loss, and with an increase in sensible heat loss. It was further accompanied by changes in hormones regulating growth and metabolism These physiological responses may result from possible alterations in PO/AH gene expression patterns (14-3-3e), suggesting a more efficient mechanism to cope with heat stress. Understanding the physiological mechanisms behind thermal conditioning step us forward to elucidate the molecular mechanism behind the PO/AH response, and response of other major organs. The thermal conditioning technique is used now in many countries including Israel, South Korea, Australia, France" Ecuador, China and some places in the USA. The improvement in growth perfom1ance (50-190 g/chicken) and thermotolerance as a result of postnatal thermal conditioning, may initiate a dramatic improvement in the economy of broiler's production.