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Journal articles on the topic 'Fosprenil'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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1

Ozherelkov, Sergey V., and Tatiana N. Kozhevnikova. "Study of adjuvant effect of fosprenil on immunogenicity of vaccines against parvovirus enteritis and rabies in experiment." Veterinaria Kubani, no. 1 (February 27, 2020): 33–35. http://dx.doi.org/10.33861/2071-8020-2020-1-33-35.

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To prevent most common viral diseases of small pets, vaccines are most often used that stimulate animal immune system and provide specific protection. Data on the adjuvant properties of well-known and widely used immunomodulator of natural origin, fosprenil, used in veterinary practice as an immunomodulator with antiviral activity for the correction of the immune response in various viral infections, during experimental immunization of BALB/mouse vaccines against dog parvovirus enteritis and rabies are presented in the article. It was shown that fosprenil use in animals at immunostimulating do
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2

Bouchemla, Fayssal, Valery Alexandrovich Agoltsov, Stepan Yuryevich Veselovsky, Sergey Vasilyevich Larionov, Olga Mikhaylovna Popova, and Dmitry Valentinovich Krivenko. "Clinical results of an inactivated anti-brucella vaccine in combination with immunomodulators." April-2020 13, no. 4 (2020): 758–63. http://dx.doi.org/10.14202/vetworld.2020.758-763.

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Aim: The aim of the study was to obtain a vaccine against animal brucellosis having high immunogenic properties by carrying an evaluation of the effectiveness of split-conjugated animal brucellosis vaccine combined with fosprenil and polypeptide C as a molecular immunomodulatory adjuvant according to the results of serological studies of the blood of animals: Agglutination reaction, complement fixation, and rose Bengal sample. Materials and Methods: Eighteen calves of Holstein Friesians breed, aged 5 months, with a living weight of 100-150 kg, were divided into three groups of six animals each
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3

Zavalishina, S. Yu. "Physiological Features of Hemostasis in Newborn Calves Receiving Ferroglukin, Fosprenil and Hamavit, for Iron Deficiency." Annual Research & Review in Biology 14, no. 2 (2017): 1–8. https://doi.org/10.9734/ARRB/2017/33617.

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Newborn calves still often suffer from iron deficiency. This state damages their growth and development - to some extent, due to the development of pathological changes in hemostasis. Thereby, both veterinary science and cattle physiology give great scientific and practical significance to the search of approaches to effective correction of new-born calves’ hemostasis pathology connected with iron deficiency. It seemed to be perspective to evaluate the influence degree of ferroglukin, traditionally applied at iron deficiency, in combination with metabolism stimulators (fosprenil and hamavit) o
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4

Kozlov, V. G., Yu Kh Khapchaev, and A. A. Ishmukhametov. "Application of Imunofan, Polioksidoniy, Ronkoleykin, Salmozan and Fosprenil for Stimulating the Humoral Immune Response in Rabbits Immunized against Enteroviruses." Epidemiology and Vaccine Prevention 15, no. 4 (2016): 53–58. http://dx.doi.org/10.31631/2073-3046-2016-15-4-53-58.

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Enterprise of viral and bacterial Preparations of Chumakov Institute of poliomyelitis and viral encephalitides, Moscow Abstract Selective and inconstant adjuvant activities of the agents Imunofan, Polioksidoniy, Roncoleykin, Salmozan and Fosprenil were determined. Those agents were used as an additional stimulant of the immune response in rabbit immunized with enteroviruses to get the polyclonal diagnostic sera for neutralization.
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5

Tukhvatullina, L. A., and R. G. Karimova. "INFLUENCE OF DRUGS "IMUNOFAN" AND "FOSPRENIL" ON MORPHOLOGICAL COMPOSITION OF BLOOD OF CALVES." Scientific Notes Kazan Bauman State Academy of Veterinary Medicine 247, no. 3 (2021): 262–66. http://dx.doi.org/10.31588/2413-4201-1883-247-3-262-266.

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The aim of the work was to study the effect of immunomodulators "Imunofan" and "Fosprenil" on the intensity of nitric oxide (II) formation and the morphological composition of blood in calves. Increased levels of stable nitric oxide (II) metabolites in the blood plasma of calves after the use of immunomodulators indicates the participation of NO in nonspecific immunity reactions. Also the established relationship between the level of stable nitric oxide (II) metabolites and the number of stab neutrophils proves that NO is one of the regulators of neutrophil activity.
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6

Tukhvatullina, L. A., and R. G. Karimova. "INFLUENCE OF IMMUNOMODULATORS ON NON-SPECIFIC RESISTANCE AND PRODUCTION OF NITRIC OXIDE (II) IN THE ORGANISM OF CALVES." Scientific Notes Kazan Bauman State Academy of Veterinary Medicine 247, no. 3 (2021): 267–72. http://dx.doi.org/10.31588/2413-4201-1883-247-3-267-272.

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The article presents data on the dynamics of bactericidal activity of blood serum against St. aureus and E. coli, and the lysozyme activity of calf blood serum against Micrococcus lisodeicticus, as well as nitrate and nitrite anions when immunomodulators are administered. It has been established that administration of «Fosprenil» increases bactericidal and lysozyme activity of blood serum, whereas, Imunophane increases nonspecific resistance without affecting lysozyme activity. Nitric oxide (II) has been shown to be directly involved in the mechanism of non-specific immunity. At the same time,
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7

Shan'shin, N. "THE IMMUNOMODULATORS COMBINED USE INFLUENCE ON THE NON-SPECIFIC RESISTANCE IN CALVES IN THE EARLY POSTNATAL REARING PERIOD." Bulletin of KSAU, no. 6 (January 22, 2025): 111–17. https://doi.org/10.36718/1819-4036-2023-6-111-117.

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he purpose of research is to study the effect of the combined use of immunomodulators on the nonspecific resistance of calves in the early postnatal period of growing. Objectives: to study the dynamics of morpho-biochemical, immunological blood parameters with the combined use of immunomodulators in calves in the early postnatal period of rearing; to determine the optimal combination, the frequency of administration of immunomodulators to calves in the early postnatal period, to increase nonspecific resistance. Research and production experience was carried out on calves of black-motley breed
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8

Yu, Zavalishina. "Physiological Features of Hemostasis in Newborn Calves Receiving Ferroglukin, Fosprenil and Hamavit, for Iron Deficiency." Annual Research & Review in Biology 14, no. 2 (2017): 1–8. http://dx.doi.org/10.9734/arrb/2017/33617.

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9

Nenchuk, M. "Hepathoprotective and dezintoxictional effect of medicine «Hamavit» and «Fospreniol» under direct and administrative application in the poultry." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 20, no. 83 (2018): 420–24. http://dx.doi.org/10.15421/nvlvet8382.

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Changes in the biochemical composition of blood among hens during experimental eimeriosis reflect the development of pathological processes in their bodies. Taking into account that eimeria affect not only the epithelial cells of the intestinal mucosa, but cause deep morphofunctional changes in the liver, we have studied the protein synthesis and detoxification properties of the chickens during the experimental eimeriosis. To solve the problems, the study was conducted on the chickens, which, by analogy, were divided into 6 groups: control (K) and 5 experimental (D1–D5) with 8 chickens in each
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10

Asrutdinova, Rezilya, Nadezhda Kanalina, Lenar Rakhmatov, and Rustem Mullakhmetov. "Morphological characteristics of chicken liver influenced by immunostimulants." BIO Web of Conferences 37 (2021): 00018. http://dx.doi.org/10.1051/bioconf/20213700018.

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The paper studies the influence of Raspol polysaccharide and fosprenil on chicken liver microstructure during vaccination against avian infectious bronchitis. The response to the integrated effects of the vaccine and immunostimulants during this period caused weakly expressed edema in perisinusoid spaces and marked activation of reticuloendothelium cells represented by the increase of Kupffer’s cells. On the 28th day after vaccination, all hepatocytes were distinguished by uniformity of magnitude and shape. They lacked evidence of prior dystrophic changes. Most hepatocytes represented actively
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11

Kozlenko, T., та O. Martyniuk. "ДОСЛІДЖЕННЯ ТЕРАПЕВТИЧНОЇ ЕФЕКТИВНОСТІ ГІПЕРІМУННОЇ СИРОВАТКИ ПРОТИ КАЛІЦИВІРУСНОЇ ІНФЕКЦІЇ КОТІВ". Scientific Messenger of LNU of Veterinary Medicine and Biotechnology 18, № 3(70) (2016): 141–46. http://dx.doi.org/10.15421/nvlvet7033.

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In Ukraine, as elsewhere in the world, feline calicivirus is one of the most common infectious diseases of cats. The main reason is the continuous growth of infections in animal populations, and high recurrence interest of feline calicivirus in cats that have undergone treatment. In addition, nowadays, it is a chronic disease. Therefore, according to existing treatment regimens, there is a need to develop new, more effective, aimed at the elimination of the pathogen through the appointment of immunomodulators, antibiotics with simultaneous application of specific medicine, including hyperimmun
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12

Asrutdinova, Rezilya, Rustem Mullahmetov, Lenar Rakhmatov, Nadezhda Kanalina, and Salavat Garipov. "Microstructure of replacement chickens’ spleen after immunostimulant application." BIO Web of Conferences 27 (2020): 00057. http://dx.doi.org/10.1051/bioconf/20202700057.

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The article presents the histological studies of replacement chickens’ spleen. The predominance of medium lymphocytes over small ones in the periarterial area was noted after vaccination with “Raspol” being an immunostimulant against chicken infectious bronchitis. In the periarterial area, the predominance of medium lymphocytes over small ones was noted. The lumen profiles of the central, trabecular arteries were well defined, and there were no signs of connective tissue disorganization in their walls. The marginal part of the lymph nodules also remained well defined especially from the inner
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13

Krotova, Olga Evgenievna, Victoria Svyatoslavovna Petrenko, Tatiana Viktorovna Alekseeva, and Konstantin Stanislavovich Savenkov. "ANTIVIRAL DRUGS AND THEIR EFFECTIVENESS IN THE TREATMENT OF CALCIVIROSIS OF CATS." SCIENTIFIC LIFE 17, no. 2 (2022): 282–94. http://dx.doi.org/10.35679/1991-9476-2022-17-2-282-294.

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Calicivirus disease of cats is widespread in the world. Members of the Felidae family are the only hosts susceptible to FCV infection. The prevalence of FCV is directly related to the number of cats present in the kennel, and is higher in large groups, for example, in colonies and shelters, where it can reach from 25 to 40%. Currently, it is relevant to study the frequency of manifestation and distribution areas of this animal disease, the search for antiviral drugs that are effective against the causative agent of calicivirus infection in cats to optimize therapeutic measures. The virus is ab
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14

Shanshin, N. V. "Joint use of polyvalent serum and immunomodulators for calves in early postnatal period." Veterinary Science Today 12, no. 3 (2023): 246–52. http://dx.doi.org/10.29326/2304-196x-2023-12-3-246-252.

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The paper demonstrates how a joint use of polyvalent serum and immunomodulators affects morbidity, survival, and resistance of calves in the early postnatal period. The objectives of the research are: to study how a joint administration of polyvalent serum and immunomodulators changes dynamics of morpho-biochemical and immunological blood parameters in calves; to determine an optimal ratio between the polyvalent serum and immunomodulators and frequency of administration so that to increase overall body resistance, ensure survival of calves in the early postnatal period; to assess cost-effectiv
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15

Газин, А. А., А. Н. Чернышева та Е. О. Рысцова. "Адаптация сердечной мышцы цыплят-бройлеров при использовании иммуномодулирующих препаратов". Bulletin of Science and Practice 372, № 7(8) (2016): 35–38. https://doi.org/10.5281/zenodo.58045.

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В работе рассмотрены различные аспекты влияния иммуномодулирующих препаратов («Гамавит» и «Фоспренил») на гистологическую и морфологическую структуру сердечной мышцы цыплят–бройлеров, закономерности морфофункциональной адаптации данного органа. На птицеводческих предприятиях при производстве мясной продукции используются цыплята–бройлеры. В рационы  кормления  часто входят иммуномодулирующие препараты, влияние которых на сердечно–сосудистую систему, на данном этапе, недостаточно освещено в современной литературе. Использование в пти
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