Academic literature on the topic 'Founder cell'

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Journal articles on the topic "Founder cell"

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Chandler, John W. "Founder cell specification." Trends in Plant Science 16, no. 11 (2011): 607–13. http://dx.doi.org/10.1016/j.tplants.2011.08.005.

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Ruiz-Gomez, M., S. Romani, C. Hartmann, H. Jackle, and M. Bate. "Specific muscle identities are regulated by Kruppel during Drosophila embryogenesis." Development 124, no. 17 (1997): 3407–14. http://dx.doi.org/10.1242/dev.124.17.3407.

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During Drosophila embryogenesis, mesodermal cells are recruited to form a complex pattern of larval muscles. The formation of the pattern is initiated by the segregation of a special class of founder myoblasts. Single founders fuse with neighbouring nonfounder myoblasts to form the precursors of individual muscles. Founders and the muscles that they give rise to have specific patterns of gene expression and it has been suggested that it is the expression of these founder cell genes that determines individual muscle attributes such as size, shape, insertion sites and innervation. We find that t
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Knirr, S., N. Azpiazu, and M. Frasch. "The role of the NK-homeobox gene slouch (S59) in somatic muscle patterning." Development 126, no. 20 (1999): 4525–35. http://dx.doi.org/10.1242/dev.126.20.4525.

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In the Drosophila embryo, a distinct class of myoblasts, designated as muscle founders, prefigures the mature pattern of somatic body wall muscles. Each founder cell appears to be instrumental in generating a single larval muscle with a defined identity. The NK homeobox gene S59 was the first of a growing number of proposed ‘identity genes’ that have been found to be expressed in stereotyped patterns in specific subsets of muscle founders and their progenitor cells and are thought to control their developmental fates. In the present study, we describe the effects of gain- and loss-of-function
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Menon, Sree Devi, Zalina Osman, Kho Chenchill, and William Chia. "A positive feedback loop between Dumbfounded and Rolling pebbles leads to myotube enlargement in Drosophila." Journal of Cell Biology 169, no. 6 (2005): 909–20. http://dx.doi.org/10.1083/jcb.200501126.

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In Drosophila, myoblasts are subdivided into founders and fusion-competent myoblasts (fcm) with myotubes forming through fusion of one founder and several fcm. Duf and rolling pebbles 7 (Rols7; also known as antisocial) are expressed in founders, whereas sticks and stones (SNS) is present in fcm. Duf attracts fcm toward founders and also causes translocation of Rols7 from the cytoplasm to the fusion site. We show that Duf is a type 1 transmembrane protein that induces Rols7 translocation specifically when present intact and engaged in homophilic or Duf–SNS adhesion. Although its membrane-ancho
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Mitchell, Simon, Koushik Roy, Thomas A. Zangle, and Alexander Hoffmann. "Nongenetic origins of cell-to-cell variability in B lymphocyte proliferation." Proceedings of the National Academy of Sciences 115, no. 12 (2018): E2888—E2897. http://dx.doi.org/10.1073/pnas.1715639115.

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Rapid antibody production in response to invading pathogens requires the dramatic expansion of pathogen-derived antigen-specific B lymphocyte populations. Whether B cell population dynamics are based on stochastic competition between competing cell fates, as in the development of competence by the bacterium Bacillus subtilis, or on deterministic cell fate decisions that execute a predictable program, as during the development of the worm Caenorhabditis elegans, remains unclear. Here, we developed long-term live-cell microscopy of B cell population expansion and multiscale mechanistic computati
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Reddy, G. V., B. Gupta, K. Ray, and V. Rodrigues. "Development of the Drosophila olfactory sense organs utilizes cell-cell interactions as well as lineage." Development 124, no. 3 (1997): 703–12. http://dx.doi.org/10.1242/dev.124.3.703.

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We have examined the mechanisms underlying the development of the olfactory sense organs on the third segment of the antenna of Drosophila. Our studies suggest that a novel developmental strategy is employed. Specification of the founder or precursor cell is not governed by the genes of the achaete-scute complex. Another basic helix-loop-helix encoding gene, atonal, is essential for determination of only a subset of the sensilla types--the sensilla coeloconica. Therefore, we predict the existence of additional proneural genes for the selection of sensilla trichoidea and sensilla basiconica. Th
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Yao, Congjun, William D. Martin, Kimberly Works, and Garth Austin. "The Human Myeloperoxidase Promoter Directs Hematopoietic Cell-Specific Transcription in Transgenic Mice." Blood 104, no. 11 (2004): 4202. http://dx.doi.org/10.1182/blood.v104.11.4202.4202.

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Abstract The myeloperoxidase (MPO) gene is expressed specifically in immature myeloid cells and not to a detectable extent in other cell types or in more mature myeloid cells. Furthermore, the MPO gene is actively transcribed both in normal myeloblasts (MPO protein constitutes about 5% of total protein in granulocytes) and in the myeloblasts of the majority of acute myeloid leukemias, but not in lymphoid leukemias or non-myeloid tumors. This has led to use of MPO activity for many years as the defining cytochemical marker for myeloid differentiation in anatomic pathology. We were the first to
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NEWTH, CYNTHIA K., CYNTHIA ARNAL, ROBERT A. GOULART, and MICHAEL H. HANNA. "Founder Cell Differentiation and Acrasin Production in an Aggregateless Mutant of Polyspondylium violaceum. (aggregation/D factor/founder cell/glorin/Polysphondylium violaceum)." Development, Growth and Differentiation 29, no. 5 (1987): 479–88. http://dx.doi.org/10.1111/j.1440-169x.1987.00479.x.

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Baker, R., and G. Schubiger. "Autonomous and nonautonomous Notch functions for embryonic muscle and epidermis development in Drosophila." Development 122, no. 2 (1996): 617–26. http://dx.doi.org/10.1242/dev.122.2.617.

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The Notch (N) gene encodes a cell signaling protein that mediates neuronal and epidermal determination in Drosophila embryos. N also regulates several aspects of myogenic development; embryos lacking N function have too many muscle founder cells and fail to properly differentiate somatic muscle. To identify cell-autonomous requirements for Notch function during muscle development, we expressed a Notch minigene in the mesoderm, but not in the ectoderm, of amorphic N-embryos. In these embryos, muscle founder hypertrophy is rescued, indicating that Notch is autonomously required by mesoderm cells
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Sens, Kristin L., Shiliang Zhang, Peng Jin, et al. "An invasive podosome-like structure promotes fusion pore formation during myoblast fusion." Journal of Cell Biology 191, no. 5 (2010): 1013–27. http://dx.doi.org/10.1083/jcb.201006006.

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Recent studies in Drosophila have implicated actin cytoskeletal remodeling in myoblast fusion, but the cellular mechanisms underlying this process remain poorly understood. Here we show that actin polymerization occurs in an asymmetric and cell type–specific manner between a muscle founder cell and a fusion-competent myoblast (FCM). In the FCM, a dense F-actin–enriched focus forms at the site of fusion, whereas a thin sheath of F-actin is induced along the apposing founder cell membrane. The FCM-specific actin focus invades the apposing founder cell with multiple finger-like protrusions, leadi
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Dissertations / Theses on the topic "Founder cell"

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Badrinath, Krishan. "Founder Cell and Myoblast Interactions during IFM Myogenesis in Drosophila: the Regulation of Myoblast Proliferation, Fusion, and Fiber Formation." Miami University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=miami1229615387.

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McIntyre, Colleen M. "Inhibition of cell migration and endothelial cell tubulogenesis by compounds found in black raspberries." Connect to resource, 2007. http://hdl.handle.net/1811/28927.

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Thesis (Honors)--Ohio State University, 2007.<br>Title from first page of PDF file. Document formatted into pages: contains [9] p.; also includes graphics. Includes bibliographical references. Available online via Ohio State University's Knowledge Bank.
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Diepenbruck, Sabine [Verfasser], and Peter [Akademischer Betreuer] Nelson. "The potential impact of Wnt5a on differentiation and phenotype of dendritic cells found in renal cell carcinoma / Sabine Diepenbruck ; Betreuer: Peter Nelson." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2017. http://d-nb.info/1148276033/34.

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Bader, S. A. "Regulation of an antigen found in tumour cells." Thesis, University of Oxford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376868.

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Jones, Patrick Emerson. "Characterization of the Rank Ligand Positive Giant Cell Found in the Interfacial Membrane." VCU Scholars Compass, 2006. http://hdl.handle.net/10156/2117.

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Waring-Green, Victoria. "Characterisation of a novel antigen found in osteoclasts and tumour cells." Thesis, University of Liverpool, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526832.

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Anderson, Ryan L. "Fatty Acid Amides and Their Biosynthetic Enzymes Found in Insect Model Systems." Scholar Commons, 2018. https://scholarcommons.usf.edu/etd/7467.

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A fatty acid amide is precisely as the name suggests: A fatty acid (CHn-COOH), in which the hydroxyl group of the carboxylic acid is displaced by an amine functional group from a biogenic amine (R-NH2), ultimately forming an amide bond. Furthermore, these fatty acid amides can be composed of a variety of different acyl chain lengths donated by the fatty acid and a myriad of different biogenic amines. Thus, these molecules can be subdivided in a number of different ways including the separation of short chain (acetyl to heptanoyl) and long chain (palmitoyl to arachidonoyl) and also based off t
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Cho, Eunkyung. "Determination via computational modeling of the structure-properties relationships in intercalated polymer:fullerene blends found in bulk-heterojunction solar cells." Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/45902.

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In bulk-heterojunction solar cells, device performance is influenced by both the intrinsic properties of the individual components - typically conjugated polymers and fullerene derivatives - and how they assemble and interact at their interface. The ability of fullerene to intercalate within the side-chains of a conjugated polymer can significantly affect the microstructure and overall device performance. Here, a series of computational chemistry approaches are applied to investigate the relationships between structure and property in intercalated polymer:fullerene blend. Using a combination o
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Finkernagel, Florian [Verfasser], and Rolf [Akademischer Betreuer] Müller. "On the transcriptome of ovarian carcinoma and immune cells found in ascites / Florian Finkernagel ; Betreuer: Rolf Müller." Marburg : Philipps-Universität Marburg, 2017. http://d-nb.info/1149544414/34.

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Osman, Jason John. "Response of GS-NSO mouse myeloma cells to pH fluctuations relevant to those found in large scale fermentation." Thesis, University of Reading, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393530.

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Books on the topic "Founder cell"

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Lodge, Thomascca 1558-1625. Rosalind: Euphues' golden legacy found after his death in his cell at Silexedra. Dovehouse, 1997.

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Donald, Beecher, ed. Rosalind: Euphues' golden legacy found after his death in his cell at Silexedra (1590). Dovehouse Editions, 1997.

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Thomas, Lodge. Rosalind: Euphues' golden legacy found after his death in his cell at Silexedra (1590). Dovehouse Editions, 1997.

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Bejan, Adrian, and Giuseppe Grazzini, eds. Shape and Thermodynamics. Firenze University Press, 2008. http://dx.doi.org/10.36253/978-88-8453-836-9.

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Shape and Thermodynamics is a two-day international Workshop focused on the Constructal Theory of generation of configuration in nature and engineering. From the early developments related to tree configurations for the cooling of electronics, today Constructal theory is being applied to conceptual design of transportation net-works, river basins, living bodies, building materials and many other flow systems. Constructal theory is also enriching thermo-dynamics, from basic theory to design and optimization. This theory approaches design "as science", with the generation of configuration regard
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Colbert, Robert A., and Paul Bowness. Immune mechanisms: HLA-B27. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198734444.003.0006.

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HLA-B27 is present in the majority of patients with ankylosing spondylitis (AS). Although we have learned a considerable amount about the natural immunologic function of HLA class I proteins, this has not provided a definitive mechanism of AS pathogenesis. While HLA-B27 is adept at presenting antigenic peptides to CD8+ T cells, ‘arthritogenic’ peptides targeted by a cross-reactive T or natural killer cell response have not been described, nor have autoreactive T cells been found. Newer concepts have evolved based on the propensity of HLA-B27 to ‘misbehave’, both inside cells and on the cell su
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Taiz, Lincoln, and Lee Taiz. Sex and the Single Cryptogam. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190490263.003.0017.

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As Chapter 17 makes clear, the asexualist/sexualists controversy continued even as Johann Hedwig and Karl von Nägel demonstrated the existence of sex in cryptogams by discovering the Alternation of Generations (1782, 1784), hybridizers A. F. Wiegman and Carl Friedrich von Gaertner recieved prestigious prizes for their work, and Giovanni Battista Amici and Adolphe-Theodore Brongniart discovered—and confirmed—the pollen tube. Unconvinced, Matthias Jacob Schleiden, co-founder of the cell theory, insisted that ferns grow asexually from spores, and that spores, not seeds, are the primary units of p
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Lees, A. J. Parkinson’s disease. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199658602.003.0008.

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The following landmark discoveries in our understanding of Parkinson’s disease are considered in this chapter: the first full medical description of the malady; consistent severe loss of pigmented cells in the substantia nigra; severe depletion of striatal dopamine; the use of high doses of racemic dopa to improve the motor symptoms; a superior animal model for the study of potential new treatments; functional lesioning and deep brain stimulation to relieve symptoms; capability of fetal dopamine cells to reinnervate the striatum and improve handicap; a compensatory phase before the emergence o
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Moerdler, Scott, and Xingxing Zang. PD-1/PDL-1 Inhibitors as Immunotherapy for Ovarian Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0010.

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Programmed death 1 (PD-1), a member of the B7-CD28 immunoglobulin superfamily, and its ligands PD-L1/PD-L2 inhibit T-cell activation. They also play a key role in the tumor microenvironment, allowing for cancer immune escape. PD-1 is induced on a variety of immune cells, including tumor-infiltrating lymphocytes (TILs), while PD-L1 is found on many types of solid tumors including ovarian cancer and some TILs. The use of immunocheckpoint inhibitors like anti-PD-1 and anti-PD-L1 therapies has been shown to reactivate the immune system to attack tumor cells. Ovarian cancers have been shown to be r
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Flanagan, Stuart. Pneumocystis jirovecii. Edited by Christopher C. Kibbler, Richard Barton, Neil A. R. Gow, Susan Howell, Donna M. MacCallum, and Rohini J. Manuel. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198755388.003.0019.

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In humans, Pneumocystis pneumonia is caused by a yeast-like fungus Pneumocystis jirovecii. Originally called P. carinii, this organism was thought to be a protozoan; however, the discovery of chitin, β‎-1,3-glucan, and ergosterol in the cell wall confirmed it as a fungus. DNA analysis demonstrated that the human disease was caused by P. jirovecii, while P. carinii was found to infect rats. P. jirovecii resides in mammalian lung tissue, usually without ill effects, but in immunocompromised hosts it becomes pathogenic and causes respiratory infection. P. jirovecii has been isolated from air and
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Anderson, James A. The Brain Doesn’t Work by Logic. Oxford University Press, 2018. http://dx.doi.org/10.1093/acprof:oso/9780199357789.003.0008.

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This chapter gives three examples of real neural computation. The conclusion is that the “brain doesn’t work by logic.” First, is the Limulus (horseshoe crab) lateral eye. The neural process of “lateral inhibition” tunes the neural response of the compound eye to allow crabs to better see other crabs for mating. Second, the retina of the frog contains cells that are selective to specific properties of the visual image. The frog responds strongly to the moving image of a bug with one class of selective retinal receptors. Third, experiments on patients undergoing neurosurgery for epilepsy found
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Book chapters on the topic "Founder cell"

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Baker, Nicholas E. "NOTCH and the Patterning of Ommatidial Founder Cells in the Developing Drosophila Eye." In Results and Problems in Cell Differentiation. Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-540-45398-7_4.

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Jiang, Jinxia, Min Feng, Annemarie Jacob, Lin Z. Li, and He N. Xu. "Optical Redox Imaging Differentiates Triple-Negative Breast Cancer Subtypes." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-48238-1_40.

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AbstractTriple-negative breast cancer (TNBC) is a highly diverse group of cancers with limited treatment options, responsible for about 15% of all breast cancers. TNBC cells differ from each other in many ways such as gene expression, metabolic activity, tumorigenicity, and invasiveness. Recently, many research and clinical efforts have focused on metabolically targeted therapy for TNBC. Metabolic characterization of TNBC cell lines can facilitate the assessment of therapeutic effects and assist in metabolic drug development. Herein, we used optical redox imaging (ORI) techniques to characterize TNBC subtypes metabolically. We found that various TNBC cell lines had differing redox statuses (levels of reduced nicotinamide adenine dinucleotide (NADH), oxidized flavin adenine dinucleotide (FAD), and the redox ratio (FAD/(NADH+FAD)). We then metabolically perturbed the cells with mitochondrial inhibitors and an uncoupler and performed ORI accordingly. As expected, we observed that these TNBC cell lines had similar response patterns to the metabolic perturbations. However, they exhibited differing redox plasticity. These results suggest that subtypes of TNBC cells are different metabolically and that ORI can serve as a sensitive technique for the metabolic profiling of TNBC cells.
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Verter, Frances, and Kyle J. Cetrulo. "Interview with Frances Verter, Founder of Parent's Guide to Cord Blood Foundation." In Perinatal Stem Cells. John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118497883.ch18.

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Froud, Stephen J., John Birch, Carol McLean, Alasdair J. Shepherd, and Kenneth T. Smith. "Viral Contaminants Found in Mouse Cell Lines Used in the Production of Biological Products." In Animal Cell Technology. Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-011-5404-8_107.

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Dvorak, Ann M. "Biochemical Contents of Granules and Lipid Bodies—Two Distinctive Organelles Found in Basophils and Mast Cells." In Blood Cell Biochemistry. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4757-9525-7_3.

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Koch-Heitzmann, I., and W. Schultze. "Compilation of volatile compounds found in plant cell cultures." In Bioflavour ’87, edited by Peter Schreier. De Gruyter, 1988. http://dx.doi.org/10.1515/9783110867121-028.

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Emmrich, F., G. Zenke, and K. Eichmann. "Isotype Restriction of Idiotopes found on Human Anti-Carbohydrate Antibodies." In The Molecular Basis of B-Cell Differentiation and Function. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-7035-2_7.

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Komuro, Terumasa. "ICC Found in the Submucosal Layer." In Atlas of Interstitial Cells of Cajal in the Gastrointestinal Tract. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-2917-9_8.

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Alvina, Fidelia B., Arvin M. Gouw, and Anne Le. "Cancer Stem Cell Metabolism." In The Heterogeneity of Cancer Metabolism. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-65768-0_12.

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AbstractCancer stem cells (CSCs), also known as tumorinitiating cells (TICs), are a group of cells found within cancer cells. Like normal stem cells, CSCs can proliferate, engage in self-renewal, and are often implicated in the recurrence of tumors after therapy [1, 2]. The existence of CSCs in various types of cancer has been proven, such as in acute myeloid leukemia (AML) [3], breast [4], pancreatic [5], and lung cancers [6], to name a few. There are two theories regarding the origin of CSCs. First, CSCs may have arisen from normal stem/progenitor cells that experienced changes in their environment or genetic mutations. On the other hand, CSCs may also have originated from differentiated cells that underwent genetic and/or heterotypic modifications [7]. Either way, CSCs reprogram their metabolism in order to support tumorigenesis.
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Maul, G. G., P. McGregory, D. Ziemnicka-Kotula, and C. Ascoli. "A New Autoantibody Specific for the Limited Systemic Sclerosis (ISSc) Found Through Molecular Biology." In Molecular and Cell Biology of Autoantibodies and Autoimmunity. Abstracts. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-46681-6_42.

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Conference papers on the topic "Founder cell"

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Deshpande, Rohan, Gregory Billus, Nikitha Penmethsa, et al. "Enabling Cell Aware Diagnosis in a Foundry for Accurate and Efficient Failure Analysis of Cell Internal Defects." In ISTFA 2020. ASM International, 2020. http://dx.doi.org/10.31399/asm.cp.istfa2020p0335.

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Abstract Cell aware diagnosis identifies defects within the standard cell as opposed to traditional layout aware diagnosis that identifies the failing standard cell or the area between two standard cells. In a mature technology dominated by random defects, cell aware results pinpoint the cell internal layer drastically reducing the turnaround time for failure analysis. This paper describes a method to enable cell aware diagnosis in a foundry environment, perform a volume diagnosis analysis with RCAD (fail mode pareto) and drive failure analysis with a quick turnaround time for a 14nm customer
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Skender, M. R., and A. Tlemcani. "Sliding mode observer control founded to series multi-cell converter." In 2015 4th International Conference on Electrical Engineering (ICEE). IEEE, 2015. http://dx.doi.org/10.1109/intee.2015.7416842.

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Otero, Carlos Tadeo Ortega, Jonathan Tse, Robert Karmazin, Benjamin Hill, and Rajit Manohar. "Automatic obfuscated cell layout for trusted split-foundry design." In 2015 IEEE International Symposium on Hardware Oriented Security and Trust (HOST). IEEE, 2015. http://dx.doi.org/10.1109/hst.2015.7140237.

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Rosenbluth, Michael J., Wilbur A. Lam, and Daniel A. Fletcher. "Contribution of Cell Mechanics to Acute Leukemia." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-59881.

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Leukostasis is a life-threatening condition that occurs when leukemia cells accumulate in the vasculature of organs such as the brain and lungs. Recent evidence has shown that leukostasis is not simply due to the physical overcrowding of leukemia cells, as previously thought, but may result from specific mechanical properties of the cells and interactions between cells. Using atomic force microscopy (AFM), we obtained direct measurements of two mechanical properties that are likely involved in this condition: (1) stiffness of individual leukemia cells and (2) non-specific adhesion forces betwe
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Weinberg, Eli, and Mohammad Mofrad. "Multiscale Fluid-Structure Simulations of the Aortic Valve." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176730.

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In the heart aortic valve, maintenance of healthy conditions and transition to diseased conditions are modulated by the cells in the valve. The cells found within the valve leaflets and walls are the valvular interstitial cells (VICs), and those found on the fluid-facing surfaces are the endothelial cells (ECs). Both types of cell are known to respond to their mechanical state; that is, the stresses and deformations imposed on the cell by its surrounding environment. Here, we present a set of simulations to examine the mechanical states of cells as the valve goes through its opening and closin
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Chasiotis, I., D. C. Street, H. L. Fillmore, and G. T. Gillies. "AFM Studies of Tumor Cell Invasion." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-43293.

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Our recent investigations on human brain tumor (glioma) cell micro and nanodynamics via AFM methodologies have shown that brain tumor invadopodia (malignant cytostructural cell extensions with sensory, motility, and invasive characteristics extended by tumor cells into their environment) can assume specific geometries based on cell plating density and the location/distance of neighboring cells indicating strong cell sensing and signaling mechanisms between malignant cells and their surroundings. In certain occasions, cancer cell processes (extensions) have been found to be highly directional m
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Tang, Xin, Tony Cappa, Theresa Kuhlenschmidt, Mark Kuhlenschmidt, and Taher A. Saif. "A Novel Way to Characterize the Non-Specific Surface Adhesion of Cancer Cells and Understand Cancer Metastasis." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-11953.

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Cancer deaths are mostly caused by the metastasis of the malignant cells, not by the primary tumor itself. During metastasis, cancer cells detach from the primary tumor, spread to different tissues via blood circulation or lymph system, and reattach to invade new tissues and organs. In this project, we hypothesize that cancer cells manage their invasion by changing their surface adhesivity. To study the cell surface adhesivity, a novel and versatile microelectromechanical systems (MEMS) force sensor is developed to quantify the strength of adhesion between living cancer cells and a probe. The
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Jerpseth, Laura, Ketan Thakare, Zhijian Pei, and Hongmin Qin. "Experimental Investigation of Effects of Extrusion Pressure on Cell Growth of Bioprinted Algae Cells in Green Bioprinting." In ASME 2020 15th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/msec2020-8481.

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Abstract In bioprinting, biomaterials are deposited layer-by-layer to fabricate structures. Bioprinting has many potential applications in drug screening, tissue engineering, and regenerative medicine. Both animal cells and plant cells can be used to synthesize bioinks. Green bioprinting uses bioinks that have been synthesized using plant cells. Constructs fabricated via green bioprinting contain immobilized plant cells, with these cells arranged at desired locations. The constructs provide scaffolds for cell growth. Printing parameters affecting the growth of cells in green bioprinted constru
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Weinberg, Eli J., and Mohammad R. K. Mofrad. "Multiscale Simulations of the Healthy and Calcific Human Aortic Valve." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192671.

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In the heart’s aortic valve, maintenance of a healthy state and transition to disease states are modulated by the cells in the valve. The cells found within the valve leaflets are valvular interstitial cells (VICs) and those found on the fluid-facing surfaces are endothelial cells (ECs). Both types of cell are known to respond to their mechanical state; that is, the stresses and deformations imposed on a cell by its surrounding environment. Here we present a set of simulations to examine these mechanical states of the cells as the valve goes through its opening and closing cycle. We have creat
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Sadana, S., M. Gupta, R. Shankar, S. Singla, H. S. Jatana, and U. Ganguly. "Demonstration of Charge Trap Flash Bit-Cell in 180nm CMOS Logic Foundry." In 2018 4th IEEE International Conference on Emerging Electronics (ICEE). IEEE, 2018. http://dx.doi.org/10.1109/icee44586.2018.8937900.

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Reports on the topic "Founder cell"

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Paul, Satashree. Flavivirus and its Threat. Science Repository, 2021. http://dx.doi.org/10.31487/sr.blog.30.

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A number of studies found that the virus can activate the endothelial cells and affect the structure and function of the blood?brain barrier, promoting immune cell migration to benefit the virus nervous system target cells infected by flaviviruses.
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Arnett, Clint, Justin Lange, Ashley Boyd, Martin Page, and Donald Cropek. Expression and secretion of active Moringa oleifera coagulant protein in Bacillus subtilis. Engineer Research and Development Center (U.S.), 2021. http://dx.doi.org/10.21079/11681/41546.

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Cationic polypeptide proteins found in the seeds of the tropical plant Moringa oleifera have coagulation efficiencies similar to aluminum and ferric sulfates without their recalcitrant nature. Although these proteins possess great potential to augment or replace traditional coagulants in water treatment, harvesting active protein from seeds is laborious and not cost-effective. Here, we describe an alternative method to express and secrete active M. oleifera coagulant protein (MO) in Bacillus subtilis. A plasmid library containing the MO gene and 173 different types of secretory signal peptides
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Jones, Robert M., Alison K. Thurston, Robyn A. Barbato, and Eftihia V. Barnes. Evaluating the Conductive Properties of Melanin-Producing Fungus, Curvularia lunata, after Copper Doping. Engineer Research and Development Center (U.S.), 2020. http://dx.doi.org/10.21079/11681/38641.

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Melanins are pigmented biomacromolecules found throughout all domains of life. Of melanins’ many unique properties, their malleable electrically conductive properties and their ability to chelate could allow them to serve as material for bioelectronics. Studies have shown that sheets or pellets of melanin conduct low levels of electricity; however, electrical conductance of melanin within a cellular context has not been thoroughly investigated. In addition, given the chelating properties of melanin, it is possible that introducing traditionally con-ductive metal ions could improve the conducti
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Hutchinson, M. L., J. E. L. Corry, and R. H. Madden. A review of the impact of food processing on antimicrobial-resistant bacteria in secondary processed meats and meat products. Food Standards Agency, 2020. http://dx.doi.org/10.46756/sci.fsa.bxn990.

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For meat and meat products, secondary processes are those that relate to the downstream of the primary chilling of carcasses. Secondary processes include maturation chilling, deboning, portioning, mincing and other operations such as thermal processing (cooking) that create fresh meat, meat preparations and ready-to-eat meat products. This review systematically identified and summarised information relating to antimicrobial resistance (AMR) during the manufacture of secondary processed meatand meat products (SPMMP). Systematic searching of eight literature databases was undertaken and the resu
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Harmful Shunting Mechanisms Found in Silicon Solar Cells (Fact Sheet). Office of Scientific and Technical Information (OSTI), 2011. http://dx.doi.org/10.2172/1016431.

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