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1

Alzamendi, Ana, Hector Del Zotto, Daniel Castrogiovanni, Jose Romero, Andres Giovambattista, and Eduardo Spinedi. "Oral Metformin Treatment Prevents Enhanced Insulin Demand and Placental Dysfunction in the Pregnant Rat Fed a Fructose-Rich Diet." ISRN Endocrinology 2012 (August 16, 2012): 1–8. http://dx.doi.org/10.5402/2012/757913.

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The intake of a fructose-rich diet (FRD) in the normal female rat induces features similar to those observed in the human metabolic syndrome phenotype. We studied the impact of FRD administration to mothers on pregnancy outcome. On gestational day (Gd) zero rats were assigned to either group: ad libitum drinking tap water alone (normal diet, ND) or containing fructose (10% w/vol; FRD) through pregnancy; all rats were fed a Purina chow diet ad libitum ND and FRD rats were daily cotreated or not with metformin (60 mg/Kg/day oral; ND + MF and FRD + MF) and submitted to a high glucose load test on
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2

Fariña, Juan Pablo, María Elisa García, Ana Alzamendi, et al. "Antioxidant treatment prevents the development of fructose-induced abdominal adipose tissue dysfunction." Clinical Science 125, no. 2 (2013): 87–97. http://dx.doi.org/10.1042/cs20120470.

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In the present study, we tested the effect of OS (oxidative stress) inhibition in rats fed on an FRD [fructose-rich diet; 10% (w/v) in drinking water] for 3 weeks. Normal adult male rats received a standard CD (commercial diet) or an FRD without or with an inhibitor of NADPH oxidase, APO (apocynin; 5 mM in drinking water; CD-APO and FRD-APO). We thereafter measured plasma OS and metabolic-endocrine markers, AAT (abdominal adipose tissue) mass and cell size, FA (fatty acid) composition (content and release), OS status, LEP (leptin) and IRS (insulin receptor substrate)-1/IRS-2 mRNAs, ROS (reacti
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3

Rivoira, María A., Alfredo Rigalli, Lucía Corball, Nori Tolosa de Talamoni, and Valeria Rodríguez. "Naringin prevents bone damage in the experimental metabolic syndrome induced by a fructose-rich diet." Applied Physiology, Nutrition, and Metabolism 47, no. 4 (2022): 395–404. http://dx.doi.org/10.1139/apnm-2021-0473.

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We analyzed the effect of naringin (NAR), a flavonoid from citric fruits, on bone quality and biomechanical properties, as well as the redox state of bone marrow in rats fed a fructose-rich diet (FRD), an experimental model to mimic human metabolic syndrome. NAR blocked the increase in the number of osteoclasts and adipocytes and the decrease in the number of osteocytes and osteocalcin (+) cells caused by FRD. Trabecular number was significantly higher in the FRD+NAR group. FRD induced a decrease in the femoral trabecular and cortical bone mineral density, which was blocked by NAR. The fractur
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4

Alzamendi, Ana, Daniel Castrogiovanni, Rolf C. Gaillard, Eduardo Spinedi, and Andrés Giovambattista. "Increased Male Offspring’s Risk of Metabolic-Neuroendocrine Dysfunction and Overweight after Fructose-Rich Diet Intake by the Lactating Mother." Endocrinology 151, no. 9 (2010): 4214–23. http://dx.doi.org/10.1210/en.2009-1353.

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An adverse endogenous environment during early life predisposes the organism to develop metabolic disorders. We evaluated the impact of intake of an iso-caloric fructose rich diet (FRD) by lactating mothers (LM) on several metabolic functions of their male offspring. On postnatal d 1, ad libitum eating, lactating Sprague-Dawley rats received either 10% F (wt/vol; FRD-LM) or tap water (controls, CTR-LM) to drink throughout lactation. Weaned male offspring were fed ad libitum a normal diet, and body weight (BW) and food intake were registered until experimentation (60 d of age). Basal circulatin
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5

Castro, María Cecilia, Hernán Gonzalo Villagarcía, Carolina Lisi Román, et al. "Chronological Appearance of Endocrine and Metabolic Dysfunctions Induced by an Unhealthy Diet in Rats." Medicina 58, no. 1 (2021): 8. http://dx.doi.org/10.3390/medicina58010008.

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Background and Objectives: The work was aimed to determine the chronological sequence of events triggered by a fructose-rich diet (FRD) (10% w/v in the drinking water) in normal rats. Material and Methods: Serum parameters, liver and islet markers of metabolism, inflammation and oxidative stress were determined weekly for 21 days. Results: At the end of the first week, rats fed with a FRD showed an early increase in circulating triglycerides, fat liver deposit, and enzymatic activity of liver glucokinase and glucose-6-phosphate dehydrogenase (G6P-DH). After two weeks of such a diet, liver gluc
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6

Miura, Akane, Masafumi Kameya, Hiroyuki Arai, Masaharu Ishii, and Yasuo Igarashi. "A Soluble NADH-Dependent Fumarate Reductase in the Reductive Tricarboxylic Acid Cycle of Hydrogenobacter thermophilus TK-6." Journal of Bacteriology 190, no. 21 (2008): 7170–77. http://dx.doi.org/10.1128/jb.00747-08.

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ABSTRACT Fumarate reductase (FRD) is an enzyme that reduces fumarate to succinate. In many organisms, it is bound to the membrane and uses electron donors such as quinol. In this study, an FRD from a thermophilic chemolithoautotrophic bacterium, Hydrogenobacter thermophilus TK-6, was purified and characterized. FRD activity using NADH as an electron donor was not detected in the membrane fraction but was found in the soluble fraction. The purified enzyme was demonstrated to be a novel type of FRD, consisting of five subunits. One subunit showed high sequence identity to the catalytic subunits
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7

Romic, Snjezana, Snezana Tepavcevic, Zorica Zakula, et al. "Does oestradiol attenuate the damaging effects of a fructose-rich diet on cardiac Akt/endothelial nitric oxide synthase signalling?" British Journal of Nutrition 109, no. 11 (2012): 1940–48. http://dx.doi.org/10.1017/s0007114512004114.

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Fructose-rich diets (FRD) cause cardiac insulin resistance manifested by impairment of Akt/endothelial NO synthase (eNOS) signalling. In contrast, oestradiol (E2) activates this signalling pathway in the heart. To study the ability of E2 to revert the detrimental effect of fructose on cardiac Akt/eNOS, female rats were subjected to a FRD and ovariectomy followed with or without E2 replacement. We also analysed the effects of the FRD and E2 on cardiac extracellular signal-regulated kinase (Erk 1/2) signalling related to their role in cardiac hypertrophy development. Expression of Akt, eNOS and
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8

Bundalo, Maja, Ana Djordjevic, Biljana Bursac, Maja Zivkovic, Goran Koricanac, and Aleksandra Stanković. "Fructose-rich diet differently affects angiotensin II receptor content in the nucleus and a plasma membrane fraction of visceral adipose tissue." Applied Physiology, Nutrition, and Metabolism 42, no. 12 (2017): 1254–63. http://dx.doi.org/10.1139/apnm-2016-0725.

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The adipose tissue renin–angiotensin system (RAS) is proposed to be a pathophysiological link between adipose tissue dysregulation and metabolic disorders induced by a fructose-rich diet (FRD). RAS can act intracellularly. We hypothesized that adipocyte nuclear membranes possess angiotensin receptor types 1 and 2 (AT1R and AT2R), which couple to nuclear signaling pathways and regulate oxidative gene expression under FRD conditions. We analyzed the effect of consumption of 10% fructose solution for 9 weeks on biochemical parameters, adipocyte morphology, and expression of AT1R, AT2R, AT1R-assoc
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9

Rather, Shagufta, Sumaya Zeerak, and Manzoor Bhat. "Favre–Racouchot disease: A clinico-dermoscopic profile." Our Dermatology Online 12, no. 4 (2021): 448–51. http://dx.doi.org/10.7241/ourd.20214.24.

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Favre–Racouchot disease (FRD) is clinically characterized by the presence of open comedones, small papules, and cystic lesions with deep wrinkles and furrows on sun-exposed areas, especially the face. FRD is a purely cosmetic disorder, with most patients not requesting treatment. Dermoscopy may play a vital role in diagnosing early lesions of FRD, averting the need for an invasive procedure such as a skin biopsy, and helping to differentiate it from close mimics. The dermoscopic features of FRD have not been reported in the literature before. We report a clinicoepidemiological profile and derm
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10

Alzamendi, Ana, Andrés Giovambattista, María E. García, Oscar R. Rebolledo, Juan J. Gagliardino, and Eduardo Spinedi. "Effect of Pioglitazone on the Fructose-Induced Abdominal Adipose Tissue Dysfunction." PPAR Research 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/259093.

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Aim. To test the potential role of PPARγin the endocrine abdominal tissue dysfunction induced by feeding normal rats with a fructose rich diet (FRD) during three weeks.Methodology. Adult normal male rats received a standard commercial diet (CD) or FRD, (10% in drinking water) without or with pioglitazone (PIO) (i.p. 0.25 mg/Kg BW/day; CD-PIO and FRD-PIO). Thereafter, we measured circulating metabolic, endocrine, and oxidative stress (OS) markers, abdominal adipose tissue (AAT) mass, leptin (LEP) and plasminogen activator inhibitor-1 (PAI-1) tissue content/expression, and leptin release by isol
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11

Khlifa, Rim, Denis A. Angers, and Alison D. Munson. "Understory Species Identity Rather than Species Richness Influences Fine Root Decomposition in a Temperate Plantation." Forests 11, no. 10 (2020): 1091. http://dx.doi.org/10.3390/f11101091.

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Different silvicultural treatments that are applied at plantation establishment may drive different vegetation succession pathways. These divergent vegetation types subsequently feed back to influence soil carbon and nitrogen cycles. One potential mechanism of feedback is through litter decomposition, and in particular fine root decomposition (FRD; <2 mm roots). In the present study we investigated how blade scarification, fertilization, and vegetation control influenced over- and understory vegetation 27 years after plantation, and whether these different vegetation communities affected FR
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12

Mano, Fukutaro, Kuo-Chung Chang, and Tomiya Mano. "Repair of Traumatic Rhegmatogenous Retinal Detachment Combined with Congenital Falciform Retinal Detachment." Case Reports in Ophthalmology 9, no. 1 (2018): 55–59. http://dx.doi.org/10.1159/000485550.

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Purpose: To report a case of surgical repair of traumatic rhegmatogenous retinal detachment combined with congenital falciform retinal detachment (FRD). Methods: A retrospective case report. Results: A 36-year-old man with traumatic rhegmatogenous retinal detachment complicating a previously known FRD was successfully treated despite residual FRD following pars plana lensectomy, vitrectomy, and encircling scleral buckling. His best corrected visual acuity improved from hand motion at 50 cm to 20/1,000. Conclusion: We concluded that the root of the FRD is susceptible to trauma because of the co
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13

Chen, Ming, Lin Zhai, Søren Brøgger Christensen, Thor G. Theander, and Arsalan Kharazmi. "Inhibition of Fumarate Reductase inLeishmania major and L. donovani by Chalcones." Antimicrobial Agents and Chemotherapy 45, no. 7 (2001): 2023–29. http://dx.doi.org/10.1128/aac.45.7.2023-2029.2001.

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ABSTRACT Our previous studies have shown that chalcones exhibit potent antileishmanial and antimalarial activities in vitro and in vivo. Preliminary studies showed that these compounds destroyed the ultrastructure of Leishmania parasite mitochondria and inhibited the respiration and the activity of mitochondrial dehydrogenases of Leishmania parasites. The present study was designed to further investigate the mechanism of action of chalcones, focusing on the parasite respiratory chain. The data show that licochalcone A inhibited the activity of fumarate reductase (FRD) in the permeabilized Leis
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14

Mallick, Urmila Basu, Marja H. Bakermans, and Khalid Saeed. "Transforming a Liability into an Asset: A System Dynamics Model for Free-Ranging Dog Population Management." Systems 9, no. 3 (2021): 56. http://dx.doi.org/10.3390/systems9030056.

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Using Indian free-ranging dogs (FRD) as a case study, we propose a novel intervention of social integration alongside previously proposed methods for dealing with FRD populations. Our study subsumes population dynamics, funding avenues, and innovative strategies to maintain FRD welfare and provide societal benefits. We develop a comprehensive system dynamics model, featuring identifiable parameters customizable for any management context and imperative for successfully planning a widescale FRD population intervention. We examine policy resistance and simulate conventional interventions alongsi
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15

Belland, Brent, James Gunn, Dan Reiley, et al. "Focal Ratio Degradation for Fiber Positioner Operation in Astronomical Spectrographs." Journal of Astronomical Instrumentation 08, no. 03 (2019): 1950007. http://dx.doi.org/10.1142/s2251171719500077.

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Focal ratio degradation (FRD), the decrease of light’s focal ratio between the input into an optical fiber and the output, is important to characterize for astronomical spectrographs due to its effects on throughput and the point spread function. However, while FRD is a function of many fiber properties such as stresses, microbending, and surface imperfections, angular misalignments between the incoming light and the face of the fiber also affect the light profile and complicate this measurement. A compact experimental setup and a model separating FRD from angular misalignment was applied to a
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16

Zhao, Ge, Yu Zhang, Yue Yang Liu, et al. "A Simulation Method of Pressure-Stress Affects Power Press Pack FRD Chip Forward Voltage." Applied Mechanics and Materials 433-435 (October 2013): 2121–24. http://dx.doi.org/10.4028/www.scientific.net/amm.433-435.2121.

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Press Pack IGBTs modules have the characteristics of easy series connection and double side cooling widely used in industry, electric power, smart grid and other fields. Press Pack FRD (Fast Recovery Diode) chips is a component of Press Pack IGBTs module. In the actual operating conditions, the electrical parameters of FRD device will change in the electrical properties under pressure-stress, especially the Forward Voltage (VF) parameters. This change of the VF parameters will have adverse effect on the reliability of FRD chip and the overall module. In this paper, according to the stress of p
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17

Hartmann, Peter, and Klaus von Wilpert. "Fine-root distributions of Central European forest soils and their interaction with site and soil properties." Canadian Journal of Forest Research 44, no. 1 (2014): 71–81. http://dx.doi.org/10.1139/cjfr-2013-0357.

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Fine-root distributions (FRDs) of forest stands are hypothesized to be a reflection of the influence of site properties on the intrinsic rooting strategies of trees. Based on forest soil survey data, we present a multivariate approach to identify the main parameters of FRD patterns of Central European forests, compare them with the FRD model according to Gale and Grigal (1987), and aim to detect the decisive site and soil properties. Two main parameters for the description of FRDs were found: one describes “shallowness” and the other additionally characterizes “divergence” from an evenly decre
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18

Tiwari, Bruce, O’Dea, and Robertson. "Utilising Group-Size and Home-Range Characteristics of Free-Roaming Dogs (FRD) to Guide Mass Vaccination Campaigns against Rabies in India." Vaccines 7, no. 4 (2019): 136. http://dx.doi.org/10.3390/vaccines7040136.

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Adequate vaccination coverage of free roaming dogs (FRD) against canine rabies is not achieved primarily due to difficulties in administering parenteral vaccinations to this population. One factor associated with this difficulty is the tendency of FRD to form groups, which increases their aggressive behavior, resulting in a significant risk of dog-bites for the vaccinators. This study investigated factors that influenced FRD forming groups and their home-ranges, using data obtained from photographic capture-recapture/sight-resight surveys conducted in rural Shirsuphal (584 sightings) and urban
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19

Wang, Zhen Yan, Zhi Mei Chen, and Jing Gang Zhang. "Simulation and Experimental Study of FRD Snubber Circuits in Buck Converter." Advanced Materials Research 463-464 (February 2012): 1350–54. http://dx.doi.org/10.4028/www.scientific.net/amr.463-464.1350.

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In buck converter, the reverse recovery failure may cause electrical spikes and deteriorate the circuit performance. In this paper, the snubber circuits for FRD in Buck converter are presented and the simulation and experimental study are investigated. RC snubber, saturated inductance snubber and RCD snubber are developed and simulated by PSpice to reduce the voltage spikes of FRD. The comparisons of the voltage spike show the advantages of the snubber circuit for the reverse recovery failure of FRD. In a Buck converter experimental system with RCD snubber circuits, the measured voltage show t
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Angeles Vasquez, Roberto Julio, Julio Miguel Angeles Suazo, Nataly Suazo, Arlitt Lozano, Jose Flores Rojas, and Hugo Abi Karam. "Forzamiento radiativo directo debido a los aerosoles atmosféricos en Perú utilizando técnicas de sensoramiento remoto." TAYACAJA 4, no. 2 (2021): 159–63. http://dx.doi.org/10.46908/tayacaja.v4i2.186.

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Describimos los resultados del estudio del espesor óptico de aerosol (EOA) y el Forzamiento Radiativo Directo (FRD) en la cima de la atmósfera (TOA), obtenidos en el periodo 2004 utilizando el sensor MODIS del satélite TERRA para Perú. Donde se observa que el valor del EOA puede tomar valores máximos alrededor de 0.5, obteniéndose como resultado el FRD de aerosol en la parte superior de la atmósfera. Los resultados indican que, la FRD está entre [-5 0] W / m2.
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21

Aslan, Belma I., Ebru Kucukkaraca, Cagri Turkoz, and Mufide Dincer. "Treatment effects of the Forsus Fatigue Resistant Device used with miniscrew anchorage." Angle Orthodontist 84, no. 1 (2013): 76–87. http://dx.doi.org/10.2319/032613-240.1.

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ABSTRACT Objective: To evaluate the dentofacial effects of the Forsus Fatigue Resistant Device (FRD) used with miniscrew anchorage (FRDMS) and compare them with those of conventional FRD and an untreated Class II control group. Materials and Methods: The sample consisted of 48 Class II subjects. Sixteen patients (13.68 ± 1.09 years of age) were treated with FRDMS, whereas 17 subjects (14.64 ± 1.56 years of age) were treated with only FRD. Also, a control sample of 15 untreated Class II subjects (14.13 ± 1.50 years of age) was constructed. Angular and linear measurements were made on 96 lateral
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22

Francini, Flavio, María C. Castro, Juan J. Gagliardino, and María L. Massa. "Regulation of liver glucokinase activity in rats with fructose-induced insulin resistance and impaired glucose and lipid metabolism." Canadian Journal of Physiology and Pharmacology 87, no. 9 (2009): 702–10. http://dx.doi.org/10.1139/y09-064.

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We evaluated the relative role of different regulatory mechanisms, particularly 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase (PFK2/FBPase-2), in liver glucokinase (GK) activity in intact animals with fructose-induced insulin resistance and impaired glucose and lipid metabolism. We measured blood glucose, triglyceride and insulin concentration, glucose tolerance, liver triglyceride content, GK activity, and GK and PFK2 protein and gene expression in fructose-rich diet (FRD) and control rats. After 3 weeks, FRD rats had significantly higher blood glucose, insulin and triglyceride levels,
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23

Bufarwa, Idris M., Ahmed A. Elamer, Collins G. Ntim, and Aws AlHares. "Gender diversity, corporate governance and financial risk disclosure in the UK." International Journal of Law and Management 62, no. 6 (2020): 521–38. http://dx.doi.org/10.1108/ijlma-10-2018-0245.

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Purpose This study aims to investigate the impact of corporate governance (CG) mechanisms on financial risk reporting in the UK. Design/methodology/approach The study uses a panel data of 50 non-financial firms belonging to 10 industrial sectors listed on the London Stock Exchange in the period 2011-2015. Multivariate regression techniques are used to examine the relationships. Findings The findings of this study reveal that CG has a significant influence on financial risk disclosure. Specifically, it is found that block ownership and board gender diversity have a positive effect on the level
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24

Maiztegui, B., M. I. Borelli, M. A. Raschia, H. Del Zotto та J. J. Gagliardino. "Islet adaptive changes to fructose-induced insulin resistance: β-cell mass, glucokinase, glucose metabolism, and insulin secretion". Journal of Endocrinology 200, № 2 (2008): 139–49. http://dx.doi.org/10.1677/joe-08-0386.

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β-Cell mass, hexokinase/glucokinase (HK/GK) activity, glucose metabolism and insulin secretion were studied in the islets of rats with fructose-induced insulin resistance (IR). Normal male Wistar rats were fed a standard commercial diet and water without (control, C) or with 10% fructose-rich diet (FRD) for 3 weeks. Blood glucose (strips), triglyceride (commercial kit), and insulin (RIA) levels were measured at the time of death. Glucose-induced insulin release, glucose metabolism (14CO2 and 3H2O production from d-[U-14C]- and d-[5-3H]-glucose) and HK/GK activity (G-6-P production), transcript
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25

AC, Spichiger, K. Allenspach, Y. Zbinden, et al. "Plasma insulin-like growth factor-1 concentration in dogs with chronic enteropathies." Veterinární Medicína 51, No. 1 (2012): 35–43. http://dx.doi.org/10.17221/5515-vetmed.

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Plasma concentrations of insulin-like growth factor (IGF)-1 were examined in dogs suffering from food-responsive diarrhea (group FRD) or inflammatory bowel disease (group IBD) before and after treatment and compared with IGF-1 values in healthy dogs (group C). Blood of 76 dogs was sampled (FRDbefore treatment, n = 23; IBD before treatment, n = 11; C, n = 42) and after treatment (FRD, n = 15; IBD, n= 8) with a hypoallergenic diet combined with (group IBD) or without prednisolone (group FRD). A clinical score (Canine IBD Activity Index = CIBDAI) was applied to judge the health status in all dogs
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26

Gerasimov, Konstantin, Oleg Dantsev, and Anton Krasyukov. "AUTOMATED CALCULATION OF STATIC CHARACTERISTICS OF SILICON FAST RECOVERY DIODES FOR APPLYING IN POWER ELECTRONICS DEVICES." Automation and modeling in design and management, no. 1 (March 17, 2022): 4–14. http://dx.doi.org/10.30987/2658-6436-2022-1-4-14.

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Calculating, analysing and verifying current-voltage characteristics (CVC) of a silicon fast-recovery diode (FRD) are performed using the methods of instrumental-technological modelling. The article determines the planar structure configuration of a semiconductor device crystal, the levels of doping and doses of irradiation with high-energy particles, at which the required values of operating and maximum forward currents and reverse (breakdown) voltages are achieved. The main tasks to be solved in the article are to determine the optimal design and technological parameters of the fast-recovery
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Koricanac, G., Ana Djordjevic, Zorica Zakula, et al. "Gender modulates development of the metabolic syndrome phenotype in fructose-fed rats." Archives of Biological Sciences 65, no. 2 (2013): 455–64. http://dx.doi.org/10.2298/abs1302455k.

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We analyzed the effects of a fructose-rich diet (FRD) to test the assumption that the expression of metabolic syndrome phenotype is different in male and female rats. Two-way ANOVA revealed a significant effect of FRD on feeding behavior and carbohydrate/lipid metabolism. The increased caloric intake in FRD rats of both sexes was followed by a cluster of gender-specific changes typical for the metabolic syndrome. Female rats were characterized by decreased glycemia, increased triglycerides, enlarged visceral adipose tissue and increased absolute mass of liver, without changes in systolic blood
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Mostert, E., and S. J. Junier. "The European flood risk directive: challenges for research." Hydrology and Earth System Sciences Discussions 6, no. 4 (2009): 4961–88. http://dx.doi.org/10.5194/hessd-6-4961-2009.

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Abstract. In recent years, flood management has shifted from protection against floods to managing the risks of floods. In Europe, this shift is reflected in the Flood risk directive of October 2007 (2007/60/EC; FRD). The FRD requires EU Member States to undertake a preliminary assessment of flood risks and, for areas with a significant flood risk, to prepare flood hazard and flood risk maps and flood risk management plans. The purpose of this paper is to introduce the FRD and discuss the challenges that the FRD poses to research. These challenges include the issue how to define and measure ''
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29

Baughn, Anthony D., and Michael H. Malamy. "The essential role of fumarate reductase in haem-dependent growth stimulation of Bacteroides fragilis." Microbiology 149, no. 6 (2003): 1551–58. http://dx.doi.org/10.1099/mic.0.26247-0.

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Haem is required for optimal growth of the bacterial anaerobe Bacteroides fragilis. Previous studies have shown that growth in the presence of haem is coincident with increased yields of ATP from glucose, expression of b-type cytochromes and expression of fumarate reductase activity. This paper describes the identification of the genes that encode the cytochrome, iron–sulfur cluster protein and flavoprotein of the B. fragilis fumarate reductase. These genes, frdC, frdA and frdB, respectively, are organized in an operon. Nonpolar, in-frame deletions of frdC and frdB were constructed in the B. f
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30

Albrecht, Mark T., and Neal L. Schiller. "Alginate Lyase (AlgL) Activity Is Required for Alginate Biosynthesis in Pseudomonas aeruginosa." Journal of Bacteriology 187, no. 11 (2005): 3869–72. http://dx.doi.org/10.1128/jb.187.11.3869-3872.2005.

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ABSTRACT To determine whether AlgL's lyase activity is required for alginate production in Pseudomonas aeruginosa, an algLΔ::Gmr mutant (FRD-MA7) was created. algL complementation of FRD-MA7 restored alginate production, but algL constructs containing mutations inactivating lyase activity did not, demonstrating that the enzymatic activity of AlgL is required for alginate production.
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31

Runkle, Erik S., and Royal D. Heins. "254 Stem Extension and Subsequent Flowering of Plugs Grown Under A Far-red-deficient Film." HortScience 35, no. 3 (2000): 435A—435. http://dx.doi.org/10.21273/hortsci.35.3.435a.

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Environments with a low red (R, 600 to 700 nm) to far-red (FR, 700 to 800 nm) ratio (e.g., with high plant density) promote stem elongation, and a high R: FR suppresses it. While FR light promotes stem extension, it is also required for rapid, uniform flowering of many long-day plants. We investigated how a new FR filter [creating a FR-deficient (FRd) environment] influenced plug growth and subsequent flowering of pansy (Viola ×wittrockiana `Crystal Bowl Yellow'), petunia (Petunia ×hybrida `Carpet Pink'), impatiens (Impatiens wallerana `Accent Rose'), snapdragon (Antirrhinum majus `Liberty Sca
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Silva, Giulliano Guimarães, Liliana Pena Naval, Luiz Di Bernardo, and Angela Di Bernardo Dantas. "Tratamento de água de reservatórios por dupla filtração, oxidação e adsorção em carvão ativado granular." Engenharia Sanitaria e Ambiental 17, no. 1 (2012): 71–80. http://dx.doi.org/10.1590/s1413-41522012000100011.

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Este trabalho teve como objetivo avaliar o tratamento de água bruta proveniente de um reservatório de água, utilizando instalação piloto de dupla filtração (DF), composta por filtro ascendente de pedregulho (FAP) e filtro rápido descendente de areia (FRD), seguida de uma unidade de pós-tratamento com carvão ativado granular (CAG). Adicionalmente, foi verificado o efeito da pré e interoxidação (entre o FAP e o FRD) na eficiência global do tratamento e na formação de subprodutos orgânicos halogenados (SOH). Em função dos resultados obtidos, foi observado que a pré-oxidação melhorou a qualidade d
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Liu, Yue Yang, Hai Long Bao, Wen Yu Gao, et al. "A Novel Fast Recovery Diode with Lower Emitter Efficiency." Applied Mechanics and Materials 433-435 (October 2013): 2222–26. http://dx.doi.org/10.4028/www.scientific.net/amm.433-435.2222.

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In this paper, a new structure of Fast Recovery Diode (FRD) and its manufacture methods were investigated. The active region designed by TCAD simulation software could achieve low emitter injection efficiency, and then reduce the peak reverse recovery current, improve the reverse recovery softness and increase working stability. Meanwhile, the effect of the P-body dose and carrier lifetime on the turn-off characteristic of FRD was also discussed. Taking an example of 3300V voltage grade devices for FRD, the reasonable P-body dose and carrier lifetime on the basis of the new structure were conf
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Celikoglu, Mevlut, Suleyman Kutalmis Buyuk, Abdullah Ekizer, and Tuba Unal. "Treatment effects of skeletally anchored Forsus FRD EZ and Herbst appliances: A retrospective clinical study." Angle Orthodontist 86, no. 2 (2015): 306–14. http://dx.doi.org/10.2319/040315-225.1.

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ABSTRACT Objective: To evaluate the skeletal, dentoalveolar, and soft tissue effects of the Forsus FRD appliance with miniplate anchorage inserted in the mandibular symphyses and to compare the findings with a well-matched control group treated with a Herbst appliance for the correction of a skeletal Class II malocclusion due to mandibular retrusion. Materials and Methods: The sample consisted of 32 Class II subjects divided into two groups. Group I consisted of 16 patients (10 females and 6 males; mean age, 13.20 ± 1.33 years) treated using the Forsus FRD EZ appliance with miniplate anchorage
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Tripathi, R. C., R. Kumar, and V. N. Tripathi. "When the Advantaged Feel Victimised: The Case of Hindus in India." Psychology and Developing Societies 31, no. 1 (2019): 31–55. http://dx.doi.org/10.1177/0971333618825085.

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This article seeks to understand the collective victimhood of the Hindus, a majority group in India, relative to the feelings of collective victimhood of the Muslim minority. It studies the role that is played by feelings of collective victimhood (CV) along with ingroup identity, fraternalistic relative deprivation (FRD), intergroup emotions and relative power in responding to intergroup conflict situations. The results showed that Hindus reported collective victimhood in greater amount compared to Muslims. Muslims felt more FRD than Hindus. Hindus also carried more negative emotions as a cons
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Bošković, Maja, Maja Živković, Goran Korićanac, et al. "Walnut Supplementation Restores the SIRT1-FoxO3a-MnSOD/Catalase Axis in the Heart, Promotes an Anti-Inflammatory Fatty Acid Profile in Plasma, and Lowers Blood Pressure on Fructose-Rich Diet." Oxidative Medicine and Cellular Longevity 2021 (April 21, 2021): 1–12. http://dx.doi.org/10.1155/2021/5543025.

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The benefits of walnut (Juglans regia) consumption for metabolic health are known, but the molecular background underlying their putative antioxidant and anti-inflammatory/immunomodulatory effects is underexplored. We assessed that walnut supplementation (6 weeks) reverted unfavorable changes of the SIRT1/FoxO3a/MnSOD/catalase axis in the heart induced by fructose-rich diet (FRD). Intriguingly, Nox4 was increased by both FRD and walnut supplementation. FRD increased the cytosolic fraction and decreased the nuclear fraction of the uniquely elucidated ChREBP in the heart. The ChREBP nuclear frac
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Giuntini, Veronica, Andrea Vangelisti, Caterina Masucci, Efisio Defraia, James A. McNamara Jr, and Lorenzo Franchi. "Treatment effects produced by the Twin-block appliance vs the Forsus Fatigue Resistant Device in growing Class II patients." Angle Orthodontist 85, no. 5 (2015): 784–89. http://dx.doi.org/10.2319/090514-624.1.

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ABSTRACT Objective: To compare the dentoskeletal changes produced by the Twin-block appliance (TB) followed by fixed appliances vs the Forsus Fatigue Resistant Device (FRD) in combination with fixed appliances in growing patients having Class II division 1 malocclusion. Materials and Methods: Twenty-eight Class II patients (19 females and 9 males; mean age, 12.4 years) treated consecutively with the TB followed by fixed appliances were compared with a group of 36 patients (16 females and 20 males; mean age, 12.3 years) treated consecutively with the FRD in combination with fixed appliances and
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Liu, Jiang, Feng He, Yueyang Liu, Rui Jin, Shaohua Dong, and Mingchao Gao. "Research on high robustness 4.5kV FRD chip." Journal of Physics: Conference Series 1486 (April 2020): 042017. http://dx.doi.org/10.1088/1742-6596/1486/4/042017.

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Eissa, Osama, Mahmoud El-Shennawy, Safaa Gaballah, Ghada El-Meehy, and Tarek El Bialy. "Treatment outcomes of Class II malocclusion cases treated with miniscrew-anchored Forsus Fatigue Resistant Device: A randomized controlled trial." Angle Orthodontist 87, no. 6 (2017): 824–33. http://dx.doi.org/10.2319/032717-214.1.

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ABSTRACT Objective: To evaluate the skeletal, dental, and soft tissue effects of the Forsus Fatigue Resistant Device (FRD) used with miniscrew anchorage and compare them with those of the conventional Forsus FRD. Materials and Methods: This study was carried out on 38 patients. These patients were randomly allocated into three groups. The 14 patients in group 1 (aged 12.76 ± 1.0 years) were treated with the FRD appliance. In group 2, the 15 patients (aged 12.52 ± 1.12 years) received treatment with FRD using miniscrew anchorage, and the 9 patients in group 3 (aged 12.82 ± 0.9 years) received n
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Li, Fa Chao, and Jian Ning Yin. "Fuzzy Roughness Degree Measurement Model Based on Level Effect." Applied Mechanics and Materials 610 (August 2014): 377–80. http://dx.doi.org/10.4028/www.scientific.net/amm.610.377.

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Nowadays there are two kinds of tools which are widely used in uncertain information processing, namely, the fuzzy sets theory and fuzzy roughness sets theory. Besides, how to construct a fusion method for the two kinds of uncertain information systematically has been a focus in both academic and applied fields. In this paper, we put forward the concept of level effect function, and analyze the characteristics of a kind of level effect function. Furthermore, we present the fuzzy roughness degree measurement model based on level effect (FRD-BLE), by combining with the roughness measurement meth
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Celikoglu, Mevlut, Tuba Unal, Mehmet Bayram, and Celal Candirli. "Treatment of a skeletal Class II malocclusion using fixed functional appliance with miniplate anchorage." European Journal of Dentistry 08, no. 02 (2014): 276–80. http://dx.doi.org/10.4103/1305-7456.130637.

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ABSTRACTBased on our literature search, we found that the use of miniplate anchorage with Forsus fatigue-resistance device (FRD) has not yet been reported. Therefore, the aim of the present case report was to present the treatment of a patient with skeletal Class II malocclusion with mandibular retrusion using Forsus FRD with miniplate anchorage. Fixed appliances with 0.022-inch slots were attached to the maxillary teeth and after 8 months of the leveling and alignment of the upper arch, 0.019 × 0.025-inch stainless steel archwire was inserted and cinched back. Two weeks after the placement of
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42

Runkle, Erik S., and Royal D. Heins. "Specific Functions of Red, Far Red, and Blue Light in Flowering and Stem Extension of Long-day Plants." Journal of the American Society for Horticultural Science 126, no. 3 (2001): 275–82. http://dx.doi.org/10.21273/jashs.126.3.275.

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For many long-day plants (LDP), adding far red light (FR, 700 to 800 nm) to red light (R, 600 to 700 nm) to extend the day or interrupt the night promotes extension growth and flowering. Blue light (B, 400 to 500 nm) independently inhibits extension growth, but its effect on flowering is not well described. Here, we determined how R-, FR-, or B-deficient (Rd, FRd, or Bd, respectively) photoperiods influenced stem extension and flowering in five LDP species: Campanula carpatica Jacq., Coreopsi ×grandiflora Hogg ex Sweet, Lobelia ×speciosa Sweet, Pisum sativum L., and Viola ×wittrockiana Gams. P
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Balanagouda, Patil, Shankarappa Sridhara, Sandip Shil, et al. "Assessment of the Spatial Distribution and Risk Associated with Fruit Rot Disease in Areca catechu L." Journal of Fungi 7, no. 10 (2021): 797. http://dx.doi.org/10.3390/jof7100797.

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Phytophthora meadii (McRae) is a hemibiotrophic oomycete fungus that infects tender nuts, growing buds, and crown regions, resulting in fruit, bud, and crown rot diseases in arecanut (Areca catechu L.), respectively. Among them, fruit rot disease (FRD) causes serious economic losses that are borne by the growers, making it the greatest yield-limiting factor in arecanut crops. FRD has been known to occur in traditional growing areas since 1910, particularly in Malnad and coastal tracts of Karnataka. Systemic surveys were conducted on the disease several decades ago. The design of appropriate ma
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Govindraj, Varun, Sanjeev Datana, Mohit Sharma, Shiv Shankar Agarwal, and Deepak Chauhan. "Improvement in Soft Tissue Profile & Upper Airway Dimensions Following Forsus FRD – A Prospective Clinical Study." Journal of Pierre Fauchard Academy (India Section) 35, no. 2 (2021): 43. http://dx.doi.org/10.18311/jpfa/2021/27278.

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<strong>Aim:</strong> To assess improvement of soft tissue profile and upper airway dimensions in skeletal Class II adolescent patients treated with Forsus Fatigue Resistant Device (FRD). <strong>Material and Methods:</strong> This prospective observational study was planned with a sample size of 15 subjects (5 male & 10 female) diagnosed with mandibular hypoplasia as a cause of Class II malocclusion, requiring fixed functional therapy, with the inclusion criteria of age of 16-25 yrs with the ANB value range of 4°+2° with a non-extraction treatment plan. Pre-f
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Ren, Lidong, and Mingbin Huang. "Fine root distributions and water consumption of alfalfa grown in layered soils with different layer thicknesses." Soil Research 54, no. 6 (2016): 730. http://dx.doi.org/10.1071/sr15126.

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Although creation of layers with different textures in topsoil is known to increase available water holding capacity (AWHC) and plant survival, little is known about associations between the layers and fine root density (FRD) or water consumption. This study investigates the effects of alternating a coarse sand layer over a finer loess layer on alfalfa growth. Soils were packed into 90-cm long columns, either individually or in alternating layers. The three layered soils had layer thicknesses of 11.25, 22.5 or 45cm. Soils were saturated, allowed to drain freely and the AWHC was determined. Alf
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Brown, D. T., Y. S. Yang, and D. B. Sittman. "Histone gene switching in murine erythroleukemia cells is differentiation specific and occurs without loss of cell cycle regulation." Molecular and Cellular Biology 8, no. 10 (1988): 4406–15. http://dx.doi.org/10.1128/mcb.8.10.4406.

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We investigated the expression characteristics of the fully replication-dependent (FRD) and the partially replication-dependent (PRD) histone gene variants by measuring changes in steady-state mRNA levels during hexamethylene bisacetamide (HMBA)-induced differentiation of murine erythroleukemia (MEL) cells. Between 24 and 60 h after induction, there was a dramatic switch in histone gene expression, such that the ratio of PRD to FRD transcripts increased severalfold over that found in uninduced MEL cells. We demonstrated that this gene switching was not simply a partial or complete uncoupling o
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Brown, D. T., Y. S. Yang, and D. B. Sittman. "Histone gene switching in murine erythroleukemia cells is differentiation specific and occurs without loss of cell cycle regulation." Molecular and Cellular Biology 8, no. 10 (1988): 4406–15. http://dx.doi.org/10.1128/mcb.8.10.4406-4415.1988.

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We investigated the expression characteristics of the fully replication-dependent (FRD) and the partially replication-dependent (PRD) histone gene variants by measuring changes in steady-state mRNA levels during hexamethylene bisacetamide (HMBA)-induced differentiation of murine erythroleukemia (MEL) cells. Between 24 and 60 h after induction, there was a dramatic switch in histone gene expression, such that the ratio of PRD to FRD transcripts increased severalfold over that found in uninduced MEL cells. We demonstrated that this gene switching was not simply a partial or complete uncoupling o
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48

Arai, Yoichi, Yu-Chin Hsu, Toru Kitagawa, Ismael Mourifié, and Yuanyuan Wan. "Testing identifying assumptions in fuzzy regression discontinuity designs." Quantitative Economics 13, no. 1 (2022): 1–28. http://dx.doi.org/10.3982/qe1367.

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We propose a new specification test for assessing the validity of fuzzy regression discontinuity designs (FRD‐validity). We derive a new set of testable implications, characterized by a set of inequality restrictions on the joint distribution of observed outcomes and treatment status at the cut‐off. We show that this new characterization exploits all of the information in the data that is useful for detecting violations of FRD‐validity. Our approach differs from and complements existing approaches that test continuity of the distributions of running variables and baseline covariates at the cut
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Sun, Baoguo, Yan Chen, Ting Xiang, et al. "The Chinese HerbJianpijieduContributes to the Regulation of OATP1B2 and ABCC2 in a Rat Model of Orthotopic Transplantation Liver Cancer Pretreated with Food Restriction and Diarrhea." BioMed Research International 2015 (2015): 1–10. http://dx.doi.org/10.1155/2015/752850.

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Traditional Chinese MedicineJianpijiedudecoction (JPJD) could improve the general status of liver cancer patients in clinics, especially the symptoms of decreased food intake and diarrhea. In this study, our results showed that the survival rate of the liver cancer with food restriction and diarrhea (FRD-LC) rats was lower than the liver cancer (LC) rats, and the tumor volume of the FRD-LC rats was higher than the LC rats. It was also shown that the high dose of JPJD significantly improved the survival rate, weight, and organ weight when compared with FRD-LC-induced rats. Moreover, JPJD admini
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Unal, Tuba, Mevlut Celikoglu, and Celal Candirli. "Evaluation of the effects of skeletal anchoraged Forsus FRD using miniplates inserted on mandibular symphysis: A new approach for the treatment of Class II malocclusion." Angle Orthodontist 85, no. 3 (2014): 413–19. http://dx.doi.org/10.2319/051314-345.1.

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ABSTRACT Objective: To evaluate the skeletal, dentoalveolar, and soft tissue effects of the Forsus Fatigue Resistant Device (FRD) appliance with miniplate anchorage for the treatment of skeletal Class II malocclusion. Material and Methods: The prospective clinical study group included 17 patients (11 girls and 6 boys; mean age 12.96 ± 1.23 years) with Class II malocclusion due to mandibular retrusion and treated with skeletal anchoraged Forsus FRD. After 0.019 × 0.025-inch stainless steel archwire was inserted and cinched back in the maxillary arch, two miniplates were placed bilaterally on th
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