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Journal articles on the topic 'Frequency Scale for Symptoms of GERD (FSSG Scale)'

Author: Grafiati

Published: 4 June 2025

Last updated: 15 July 2025

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1

Mushtaq, Zobia, Bushra Adeel, Tanveer Hussain, Mazhar Ali, Muhammad Ayyaz, and Imran Joher. "A Prospective Observational Study Combinition of Proton Pump Inhibitors with Prokinetics in Gerd." Pakistan Journal of Medical and Health Sciences 16, no. 9 (2022): 427–29. http://dx.doi.org/10.53350/pjmhs22169427.

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Background: Gastroesophageal reflux disease (GERD), a fairly common ailment that has a negative influence on quality of life. 30- 40% of patients with GERD have an insufficient response to standard PPIs therapy. For subjects resistant to this PPI therapy, double the PPI dosage or switch to different PPIs, which may not be ideal. So, combination therapy with prokinetic agent will significantly improve GERD symptoms. Study Design: A prospective observational study. Place and Duration: In the Department of Medicine, Faisalabad Medical University, Faisalabad from May 2022 to July 2022. Material an

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Paliy, I. G., S. V. Zaika, K. V. Ksenchyna, and I. V. Chernova. "Validation of the Frequency Scale for the Symptoms of GERD (FSSG) questionnaire for Ukrainian-speaking population in Vinnytsia region." Modern Gastroenterology, no. 4 (December 16, 2024): 30–37. https://doi.org/10.30978/mg-2024-4-30.

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Gastroesophageal reflux disease (GERD) is one of the most common pathologies of the digestive system. The main complaint is heartburn. The prevalence of gastroesophageal reflux disease is expected to remain high and even increase. Objective — to translate and adapt the Frequency Scale for the Symptoms of GERD (FSSG) questionnaire into Ukrainian and validate its use among the Ukrainian‑speaking population in Vinnytsia region as a screening tool for gastroesophageal reflux disease. Materials and methods. The process of cross‑cultural adaptation of the English version was carried out in accordanc

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Faruqui, Arif Ahmed. "Need of Combining Proton Pump Inhibitors with Prokinetics: A Prospective Observational Survey Conducted in India." Journal of Medicine 19, no. 2 (2018): 74–78. http://dx.doi.org/10.3329/jom.v19i2.37223.

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Background: Gastro esophageal reflux disease (GERD), a highly prevalent disorder has adverse impact on quality of life. An estimated 40% of GERD patients have incomplete response to standard PPI therapy. For these PPI refractory patients, doubling the PPI dose or switching to another PPI are pursued by the treating physicians that might not be optimal. Therefore, an appropriate second line treatment should focus on addition of gastro-prokinetic drugs that stimulates gastric motility.Materials & Methods: This was a prospective observational study conducted in 118 patients suffering from sym

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Kusano, Motoyasu, Yasuyuki Shimoyama, Sayaka Sugimoto, et al. "Development and evaluation of FSSG: frequency scale for the symptoms of GERD." Journal of Gastroenterology 39, no. 9 (2004): 888–91. http://dx.doi.org/10.1007/s00535-004-1417-7.

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Alkhaldi, Reem, Shatha Almuwallad, Fayrouz Khateeb, Hiyam Qanadily, Heba Adly, and Majed Obaid. "Gastroesophageal Reflux Disease (GERD) and its Association with Anxiety and Depression: An Online Cross-Sectional Survey Among Saudi Population." Journal of Umm Al-Qura University for Medical Sciences 10, no. 1 (2024): 54–60. http://dx.doi.org/10.54940/ms35393369.

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Background: Gastroesophageal reflux disease occurs when gastric juice flows into the esophagus. The presence of psychological issues may increase the risk of GERD, such as anxiety and depression. This study aims to determine the association between GERD symptoms and psychological issues. Methods: A cross-sectional study was done using an online questionnaire distributed through social media platforms (Facebook, Twitter, WhatsApp, Snapchat) to all Saudi residents ≥18 years of both genders. Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale (HADS). The Frequency

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Nomura, Masatoshi, Naotaka Tashiro, Tetsuhiro Watanabe, et al. "Association of Symptoms of Gastroesophageal Reflux with Metabolic Syndrome Parameters in Patients with Endocrine Disease." ISRN Gastroenterology 2014 (January 30, 2014): 1–6. http://dx.doi.org/10.1155/2014/863206.

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Background. Metabolic syndrome (MetS) and obesity are known risk factors for gastroesophageal reflux disease (GERD), which is often found in patients with endocrine disorders, such as thyroid dysfunction and hypopituitarism. To clarify the relationship of endocrine disease with GERD, we investigated the symptoms of GERD in patients with various endocrine diseases. Methods. Patients with various endocrine disorders who visited Kyushu University Hospital were included. GERD symptoms were examined using a self-administered questionnaire, the frequency scale for the symptoms of GERD (FSSG). Metabo

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Ayesha, Abdul Bari, Syed Ibrahim Hassan Dr., Najmus Sahar Aaminah, Batool Safiyya Syeda, and Asif Rasheed Dr. "A PROSPECTIVE STUDY INVOLVING COMPARISON OF ACOTIAMIDE WITH RABEPRAZOLE VS. DOUBLE DOSE RABEPRAZOLE IN PATIENTS HAVING OVERLAPPING SYMPTOMS OF PROTON PUMP INHIBITOR REFRACTORY GASTROESOPHAGEAL REFLUX DISEASE AND FUNCTIONAL DYSPEPSIA." International Journal of Research - Granthaalayah 8, no. 1 (2020): 1–11. https://doi.org/10.5281/zenodo.3630666.

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Introduction: Gastroesophageal reflux disease (GERD) is a digestive disorder that affects the lower esophageal sphincter (LES). Functional dyspepsia (FD) is characterized by troublesome early satiety, epigastralgia or heart burn. It is often overlooked as the symptoms overlap with GERD. This study aims to compare the effectiveness of Acotiamide+Rabeprazole vs. a double dose of Rabeprazole in Indian population. Method: In this study 60 patients diagnosed with PPI refractory GERD (taking PPI>8weeks) and FD with no gastric or duodenal organic abnormalities were randomly allocated in two groups

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Inoue, Haruhiro, Mayo Tanabe, Enrique Rodríguez de Santiago, et al. "Anti-reflux mucosal ablation (ARMA) as a new treatment for gastroesophageal reflux refractory to proton pump inhibitors: a pilot study." Endoscopy International Open 08, no. 02 (2020): E133—E138. http://dx.doi.org/10.1055/a-1031-9436.

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Abstract Background The incidence of proton pump inhibitor (PPI)-refractory gastroesophageal reflux disease (GERD) has been increasing. While surgical intervention with Laparoscopic Nissen Fundoplication remains the gold standard, less invasive anti-reflux interventions are desired. We have developed a minimally invasive anti-reflux mucosal ablation (ARMA) treatment. Herein, we report its technical details and describe its feasibility, safety, and efficacy in PPI-refractory GERD. Methods We conducted a prospective single-center single-arm interventional trial evaluating the outcome of ARMA in

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Shiota, Seiji, Kazunari Murakami, Kunimitsu Inoue, et al. "Risk Factors for Dysmotility, Acid Reflux Symptoms, and Overlap Using FSSG in Japan." Epidemiology Research International 2012 (October 15, 2012): 1–7. http://dx.doi.org/10.1155/2012/984039.

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Aims. FSSG {frequency scale for the symptoms of gastroesophageal reflux disease (GERD)} was developed as a diagnostic tool for dysmotility and acid reflux symptoms. We first used FSSG to investigate the prevalence and risk factors for dysmotility and acid reflux symptoms and overlap of the two symptoms in a Japanese population. Methods. A cross-sectional survey was performed in Japanese underwent the routine medical examination. Dysmotility and acid reflux symptom were diagnosed by using FSSG. Subjects met both criteria were considered as overlap group. Results. Among 778 subjects, 395 persons

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Sugihartono, Titong, Amal Arifi Hidayat, Ricky Indra Alfaray та ін. "IL-8, TNF-α, and IL-17 in the Development of Erosive Esophagitis and Symptom Perception in Gastroesophageal Reflux Disease (GERD)". Journal of Clinical Medicine 13, № 19 (2024): 5832. http://dx.doi.org/10.3390/jcm13195832.

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Background: The diverse clinical characteristics of erosive esophagitis (EE) and symptom perception in patients with gastroesophageal reflux disease (GERD) remain a major challenge in understanding their underlying pathogenesis. This study aimed to investigate the association between the levels of IL-8, TNF-α, and IL-17 in serum and the presence of erosive esophagitis and symptoms related to GERD. Method: We enrolled 65 subjects presenting with GERD symptoms. Based on the findings of upper endoscopy, the subjects were categorized into two groups: (1) erosive esophagitis (EE LA grades B-D) and

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Bari, Ayesha Abdul, Dr Syed Ibrahim Hassan, Aaminah Najmus Sahar, Syeda Batool Safiyya, and Asif Rasheed. "A PROSPECTIVE STUDY INVOLVING COMPARISON OF ACOTIAMIDE WITH RABEPRAZOLE VS. DOUBLE DOSE RABEPRAZOLE IN PATIENTS HAVING OVERLAPPING SYMPTOMS OF PROTON PUMP INHIBITOR REFRACTORY GASTROESOPHAGEAL REFLUX DISEASE AND FUNCTIONAL DYSPEPSIA." International Journal of Research -GRANTHAALAYAH 8, no. 1 (2020): 1–11. http://dx.doi.org/10.29121/granthaalayah.v8.i1.2020.234.

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Introduction: Gastroesophageal reflux disease (GERD) is a digestive disorder that affects the lower esophageal sphincter (LES). Functional dyspepsia (FD) is characterized by troublesome early satiety, epigastralgia or heart burn. It is often overlooked as the symptoms overlap with GERD. This study aims to compare the effectiveness of Acotiamide+Rabeprazole vs. a double dose of Rabeprazole in Indian population. Method: In this study 60 patients diagnosed with PPI refractory GERD (taking PPI>8weeks) and FD with no gastric or duodenal organic abnormalities were randomly allocated in two

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Gehlot, Valentina, Akshita Mathur, Kunal Das, Shweta Mahant, and Rajashree Das. "No Association between Helicobacter pylori and Gastroesophageal Reflux Disease: A Comprehensive Risk Factor Analysis in North Indian Patients." Biomedical and Biotechnology Research Journal 8, no. 2 (2024): 243–50. http://dx.doi.org/10.4103/bbrj.bbrj_157_24.

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Abstract Background: The relationship between gastroesophageal reflux disease (GERD) and Helicobacter pylori infection is a complicated topic. This study aimed to evaluate the association between H. pylori infection and GERD and identify the associated risk factors in North India. Methods: All individuals who were referred for an endoscopy because they had dyspepsia were included in a cross-sectional study. Using endoscopic assessment, GERD was diagnosed. As a comparison group, patients with normal esophageal function were chosen. H. pylori was cultured and genotyped to assess the virulent gen

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Jibran Umar Ayub, Ayesha Qaisar, Said Amin, Mehreen Zaman, Azhar Zahir Shah, and Farooq Ahmed. "Clinical Efficacy of Dexlansoprazole vs Esomeprazole in Gastro-Oesophageal Reflux Disease: A Randomized Clinical Trial." Journal of Saidu Medical College, Swat 12, no. 3 (2022): 112–17. http://dx.doi.org/10.52206/jsmc.2022.12.3.699.

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Background: Gastro-Esophageal reflux disease (GERD) is a very common problem in a gastrointestinal clinical setting. Still, the best treatment for it remains debatable as there are many new drugs that have evolved for its treatment in addition to dietary modification.Objective: To compare the clinical efficacy of Dexlansoprazole (modified-release 60 mg) and esomeprazole (40 mg) for the resolution of symptoms of GERD.Material and Methods: This randomized controlled trial or intervention was conducted for comparing the clinical efficacy of Dexlansoprazolevs Esomeprazole for the symptomatic treat

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Bulqaini, Alul Azmi, and Darmadi. "Relationship between Degrees of Severity Gastroesophageal Reflux Disease (Gerd) with Quality of Life." Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) 4, no. 3 (2023): 96–103. http://dx.doi.org/10.32734/jetromi.v4i3.10884.

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Background. Gastroesophageal reflux disease (GERD) is a pathological condition caused by the reflux of gastric contents into the esophagus, with symptoms that appear inside and outside the esophagus which can reduce the patient's quality of life. The aim study is to analyze the relationship between the severity of GERD and the quality of life of students Faculty of Medicine at Universitas Sumatera Utara (USU) in 2019 and 2020. Method. Cross-sectional research with a sampling technique in the form of total sampling. Data collection was carried out using an online questionnaire in the form of a

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Teimouri, Azam, and Babak Amra. "Association between Sleep Quality and Gastroesophageal Reflux in Medical Students." Middle East Journal of Digestive Diseases 13, no. 2 (2021): 139–44. http://dx.doi.org/10.34172/mejdd.2021.217.

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BACKGROUND Due to stressful occupational conditions, irregular dietary and sleep schedules, medical students are at increased risk of developing gastrointestinal disorders, gastroesophageal reflux (GERD) in particular, as well as sleep disturbances. Therefore, for the first time, we aimed to assess the correlation between GERD and sleep disturbances among medical students. METHODS The current cross-sectional study was done on 290 medical students at different study periods in Iran during 2018-2019. Age, sex, stage of studying, residence, and body mass index were gathered. The frequency scale f

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Shimada, Yuji, Akihito Nagahara, Mariko Hojo, et al. "Upper Gastrointestinal Mucosal Injury and Symptoms in Elderly Low-Dose Aspirin Users." Gastroenterology Research and Practice 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/252963.

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Background. We investigated the prevalence, symptoms, and QOL impact of esophageal (EI), gastric (GI), and duodenal mucosal injury (DI) individually between low-dose aspirin (LDA) users and nonusers to reveal the clinical features of LDA-related mucosal injury.Methods. Data were extracted from the records of subjects who underwent upper gastrointestinal endoscopy at our department between April 2008 and December 2013. Responses from 3162 elderly patients on Frequency Scale for Symptoms of GERD (FSSG) and SF-8 QOL questionnaires (SF-8) were analyzed. FSSG items were classified into total score

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Mizokami, Daisuke, Hirohumi Harada, Toshihiko Katoh, and Takashi Nakagawa. "A Clinical Investigation of Frequency Scale for the Symptoms of GERD (FSSG) for Foreign Body Sensation in the Throat." Koutou (THE LARYNX JAPAN) 18, no. 2 (2006): 141–45. http://dx.doi.org/10.5426/larynx1989.18.2_141.

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Tandukar, Sudarshan, and Ansu Mali Joshi. "Incidence of gastro-esophageal reflux disease associated with type 2 diabetes." Journal of Universal College of Medical Sciences 3, no. 3 (2015): 32–34. http://dx.doi.org/10.3126/jucms.v3i3.24246.

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BACKGROUND: Gastro-Esophageal Reflux Disease is a growing problem with a reportedly increasing prevalence in type 2 diabetes patients. Despite this, study on the prevalence of Gastro-Esophageal Reflux Disease in Nepalese patients with type 2 diabetes is not available. The objective of this study is to determine the incidence of Gastro-Esophageal Reflux Disease in Nepalese patients with type 2 diabetes. MATERIAL AND METHODS: This cross-sectional study was carried out for a period of three months in patients with type 2 diabetes. A structured questionnaire “Frequency Scale for the Symptoms

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L, Gathara. "GERD and Its Association with BMI in Adult Patients Undergoing Upper GI Endoscopy at the Kenyatta National Hospital." Gastroenterology & Hepatology International Journal 7, no. 1 (2022): 1–11. http://dx.doi.org/10.23880/ghij-16000191.

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Background: Gastroesophageal reflux disease (GERD) is a common clinical problem affecting millions of people worldwide. GERD is highly prevalent in morbidly obese patients and a high body mass index (BMI) is a risk factor for this condition. However, there is differing data on the use of BMI as a predictor of GERD, its severity and frequency. We therefore aimed to determine the association between GERD and high BMI and to document the esophageal mucosal changes in these patients during endoscopy. Methodology: We conducted a cross-sectional study among the 174 GERD patients to investigate the a

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Tsutsui, Hideaki, Noriaki Manabe, Jiro Hata, et al. "Tu1134 Frequency Scale for Symptoms of GERD (FSSG) and the Upper Gastrointestinal Endoscopic Findings of Patients With Laryngopharyngeal Reflux Disease (LPRD)." Gastroenterology 142, no. 5 (2012): S—755. http://dx.doi.org/10.1016/s0016-5085(12)62928-x.

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Watanabe, Tetsuo, and Masashi Suzuki. "Frequency Scale for Symptoms of GERD (FSSG) and the Severity of an Abnormal Sensation in the Throat in Patients with Globus Pharyngeus." Practica Oto-Rhino-Laryngologica 102, no. 6 (2009): 465–71. http://dx.doi.org/10.5631/jibirin.102.465.

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Ito, Kyoko, Takashi Wada, Hisao Tajiri, and Mikio Zeniya. "S1933 Detection of Predictive Factors and Assessment of Therapeutic Effects for Gastro-Esophageal Reflux Diseases (GERD) Using a Novel System FSSG (Frequency Scale for Symptoms of GERD)." Gastroenterology 136, no. 5 (2009): A—295. http://dx.doi.org/10.1016/s0016-5085(09)61348-2.

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Song, Shunzhe, Yunshu Zhang, Jingwen Zhang, Yongshan Jiang, and Aixia Gong. "Efficacy evaluation and exploratory analysis of influencing factors of Banxia Houpu Decoction in the treatment of refractory gastroesophageal reflux disease." Medicine 103, no. 24 (2024): e38045. http://dx.doi.org/10.1097/md.0000000000038045.

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Approximately 10% to 40% of patients with gastroesophageal reflux disease (GERD) exhibit poor response to proton pump inhibitors (PPIs), indicating refractory GERD (RGERD). Banxia Houpu Decoction is a traditional Chinese medicine formula used for treating GERD, particularly for atypical symptoms. This study aimed to investigate the improvement of different symptoms in RGERD patients treated with Banxia Houpu Decoction and identify relevant factors influencing its efficacy. From November 2021 to November 2022, a total of 89 RGERD patients voluntarily participated in this clinical study at our h

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Paliy, I. G., S. V. Zayika, I. V. Chernova, and A. G. Kapitun. "Dyspepsia in medical university students: prevalence of symptoms and risk factors." Reports of Vinnytsia National Medical University 28, no. 3 (2024): 490–501. http://dx.doi.org/10.31393/reports-vnmedical-2024-28(3)-20.

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Annotation. Dyspepsia is one of the most common symptom complex encountered in internal medicine and includes a group of symptoms related to the gastroduodenal region of the gastrointestinal tract. The purpose of the research was to study the prevalence of dyspepsia symptoms among the 1-6 years students of National Pirogov Memorial Medical University, Vinnytsya, who did not seek medical help for symptoms of dyspepsia and also to establish risk factors for its development among the students in comparison with general practitioners. Using the Microsoft Forms platform we conducted a survey of 300

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Paliу, Iryna, Serhii Zaika, Inna Chernova, Alla Kapitun, and Mariia Shemeta. "Dyspepsia in Medical University Students and General Practitioners." Family medicine. European practices, no. 1 (February 27, 2025): 48–54. https://doi.org/10.30841/2786-720x.1.2025.324236.

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Dyspepsia is a common complex of symptoms encountered in internal medicine and includes a group of symptoms related to the gastroduodenal region of the gastrointestinal tract. The objective: the purpose of the research is to study the prevalence of dyspepsia symptoms among the 1-6 years students of National Pirogov Memorial Medical University, Vinnytsya, who had dyspepsia symptoms but did not ask for medical help and to establish risk factors for dyspepsia development among the students in comparison with general practitioners. Materials and methods. Using the Microsoft Forms platform we surve

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Paliу, Iryna, Serhii Zaika, Inna Chernova, Alla Kapitun, and Mariia Shemeta. "Dyspepsia in Medical University Students and General Practitioners." Family Medicine. European Practices, no. 1 (February 27, 2025): 48–54. https://doi.org/10.30841/2786-720X.1.2025.324236.

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Dyspepsia is a common complex of symptoms encountered in internal medicine and includes a group of symptoms related to the gastroduodenal region of the gastrointestinal tract. <strong>The objective:</strong> the purpose of the research is to study the prevalence of dyspepsia symptoms among the 1-6 years students of National Pirogov Memorial Medical University, Vinnytsya, who had dyspepsia symptoms but did not ask for medical help and to establish risk factors for dyspepsia development among the students in comparison with general practitioners. <strong>Materials and methods.</strong>&nbsp

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Miyamoto, Masaki, Keisuke Takeuchi, and Ken Haruma. "M1915 Efficacy of Addition of Prokinetics for Proton Pump Inhibitor (PPI)-Resistant Non-Erosive Reflux Disease (NERD) Patients: Significance of Frequency Scale for the Symptoms of GERD(FSSG) On Decision of Treatment Strategy." Gastroenterology 136, no. 5 (2009): A—445. http://dx.doi.org/10.1016/s0016-5085(09)62050-3.

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Miyamoto, Masaki, Noriaki Manabe, and Ken Haruma. "Efficacy of the Addition of Prokinetics for Proton Pump Inhibitor (PPI) Resistant Non-erosive Reflux Disease (NERD) Patients: Significance of Frequency Scale for the Symptom of GERD (FSSG) on Decision of Treatment Strategy." Internal Medicine 49, no. 15 (2010): 1469–76. http://dx.doi.org/10.2169/internalmedicine.49.3615.

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Komatsu, Yasuhiko, Hiroyasu Miura, Yoshitaka Iwama, and Yoshihisa Urita. "Beneficial Effect of Heat-Killed Lactic Acid Bacterium Lactobacillus johnsonii No. 1088 on Temporal Gastroesophageal Reflux-Related Symptoms in Healthy Volunteers: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study." Nutrients 16, no. 8 (2024): 1230. http://dx.doi.org/10.3390/nu16081230.

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A randomized, placebo-controlled, double-blind, parallel-group clinical study was conducted to examine the effects of ingesting a heat-killed lactic acid bacterium, Lactobacillus johnsonii No. 1088 (LJ88) on temporal gastroesophageal reflux-related symptoms in healthy volunteers. A total of 120 healthy Japanese volunteers of both sexes, aged between 21 and 63 years, whose Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease (FSSG) total score was 8 or greater, but who were not diagnosed with functional dyspepsia according to the Rome IV classification, were enrolled. They were r

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Zohalinezhad, Mohammad E., Mohammad Kazem Hosseini-Asl, Rahimeh Akrami, Majid Nimrouzi, Alireza Salehi, and Mohammad M. Zarshenas. "Myrtus communis L. Freeze-Dried Aqueous Extract Versus Omeprazol in Gastrointestinal Reflux Disease." Journal of Evidence-Based Complementary & Alternative Medicine 21, no. 1 (2015): 23–29. http://dx.doi.org/10.1177/2156587215589403.

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The current work assessed a pharmaceutical dosage form of Myrtus communis L. (myrtle) in reflux disease compared with omeprazol via a 6-week double-blind randomized controlled clinical trial. Forty-five participants were assigned randomly to 3 groups as A (myrtle berries freeze-dried aqueous extract, 1000 mg/d), B (omeprazol capsules, 20 mg/d), and C (A and B). The assessment at the beginning and the end of the study was done by using a standardized questionnaire of frequency scale for the symptoms of gastroesophageal reflux disease (FSSG). In all groups, both reflux and dyspeptic scores signi

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Maeda, Tetsuya, Ken Nagata, Yuichi Satoh, Takashi Yamazaki, and Daiki Takano. "High Prevalence of Gastroesophageal Reflux Disease in Parkinson’s Disease: A Questionnaire-Based Study." Parkinson's Disease 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/742128.

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The aim of this study is to investigate the frequency and clinical features of gastroesophageal reflex disease (GERD) in Parkinson’s disease (PD). Consecutively recruited PD patients and controls were questioned about heartburn and GERD with a questionnaire. In PD patients, disease duration and severity, quality of life, and nonmotor symptoms were also examined and then the clinical features of GERD were analyzed. A total of 102 patients and 49 controls were enrolled and 21 patients and 4 controls had heartburn, significantly frequent in PD. The prevalence rate of GERD was 26.5% in PD and the

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Lee, Hesol, Changsub Yang, Ojin Kwon, Ki-Byoung Kim, Wongu Lee, and Sungha Kim. "Effectiveness analysis of herbal medicine for gastroesophageal reflux disease: A retrospective study." Medicine 103, no. 8 (2024): e37295. http://dx.doi.org/10.1097/md.0000000000037295.

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This study aimed to identify the clinical features of gastroesophageal reflux disease (GERD) in primary clinics and the effectiveness and safety of herbal medicine (HM). Thirty-five patients with gastroesophageal-reflux symptom who visited the 16 Korean medicine (KM) primary clinics from June 2022 to October 2022 were included in the study. We retrospectively analyzed the charts of 35 patients and collected clinical characteristics, HM, and outcome variables such as the numerical rating scale, gastroesophageal reflux disease questionnaire, frequency scale for symptoms of gastroesophageal reflu

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Ohmure, H., K. Kanematsu-Hashimoto, K. Nagayama, et al. "Evaluation of a Proton Pump Inhibitor for Sleep Bruxism." Journal of Dental Research 95, no. 13 (2016): 1479–86. http://dx.doi.org/10.1177/0022034516662245.

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Bruxism is a repetitive jaw-muscle activity characterized by clenching or grinding of the teeth and/or bracing or thrusting of the mandible. Recent advances have clarified the relationship between gastroesophageal reflux and sleep bruxism (SB). However, the influence of pharmacological elimination of gastric acid secretion on SB has not been confirmed. The authors aimed to assess the efficacy of a proton pump inhibitor (PPI) on SB and to examine the gastrointestinal (GI) symptoms and endoscopic findings of the upper GI tract in SB patients. The authors performed a randomized double-blind place

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Sukharamwala, Prashant, Anthony Teta, Sharona Ross, et al. "Over 250 Laparoendoscopic Single Site (LESS) Fundoplications: Lessons Learned." American Surgeon 81, no. 9 (2015): 870–75. http://dx.doi.org/10.1177/000313481508100919.

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Laparoendoscopic single site (LESS) surgery is a more recent advance in the progression of minimally invasive surgery. This study was undertaken to assess lessons learned after our first 250 LESS fundoplications for gastroesophageal reflux disease (GERD). All patients undergoing LESS fundoplications were prospectively followed from 2008 to 2014. Patients scored the frequency/severity of their symptoms before/after LESS fundoplication using a Likert scale (0 = never/not bothersome to 10 = always/very bothersome). Patients also scored satisfaction with their incision using a Likert scale (1 = re

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Paré, Pierre, François Meyer, David Armstrong, Myron Pyzyk, Dan Pericak, and Goeree Ron. "Validation of the GSFQ, a Self-Administered Symptom Frequency Questionnaire for Patients with Gastroesophageal Reflux Disease." Canadian Journal of Gastroenterology 17, no. 5 (2003): 307–12. http://dx.doi.org/10.1155/2003/530984.

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BACKGROUND: Although the diagnosis of gastroesophageal reflux disease (GERD) is based primarily on symptoms experienced by a patient, relatively little attention has been paid to the development and validation of self-administered questionnaires specific to GERD symptoms. The present article presents the validation of the short, self-administered GERD Symptom Frequency Questionnaire (GSFQ).METHODS: Patients with GERD participating in a randomized clinical trial comparing pantoprazole and nizatidine were asked to complete the GSFQ together with validated instruments for measurement of health-re

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Oparin, O. A., and O. M. Kashyrtseva. "Characteristics of psychosomatic disorders in patients with gastroesophageal reflux disease with concomitant obesity." Shidnoevropejskij zurnal vnutrisnoi ta simejnoi medicini 2022, no. 2 (2022): 91–95. http://dx.doi.org/10.15407/internalmed2022.02.091.

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Purpose: To investigate the frequency and severity of psychosomatic disorders in patients with gastroesophageal reflux disease with comorbid obesity and patients with GERD without concomitant pathology, to evaluate the influence of psychoemotional state on the clinical picture of GERD. Materials and results. 90 patients and 20 practically healthy individuals took part in the study. The first group included GERD patients with accompanying obesity, the second group included GERD patients without accompanying pathology and the control group. Surveys were conducted using the GERDQ questionnaire, t

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Nandurkar, Sanjay. "Frequency scale symptoms for gastroesophageal reflux disease (Frequency Scale for Symptoms of GERD) predicts need for addition of prokinetics to proton pump inhibitor therapy." Journal of Gastroenterology and Hepatology 23, no. 8pt1 (2008): 1165–67. http://dx.doi.org/10.1111/j.1440-1746.2008.05517.x.

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Cheng, Jing, and Arthur C. Ouwehand. "Gastroesophageal Reflux Disease and Probiotics: A Systematic Review." Nutrients 12, no. 1 (2020): 132. http://dx.doi.org/10.3390/nu12010132.

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Probiotic is little known for its benefits on upper gastrointestinal health. The objective of this systematic review was to examine the efficacy of probiotics in alleviating the frequency and severity of symptoms in gastroesophageal reflux disease (GERD) in the general adult population. The PubMed and Web of Science databases were searched for prospective studies on GERD, heartburn, regurgitation, and dyspepsia, without any limitation on sample size. The Jadad scale was used to evaluate the quality of randomized controlled trials. In total, 13 prospective studies that were published in 12 arti

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Krishan Gopal and Shashi Shekhar. "Role of Probiotics in Reducing GERD." International Journal of Contemporary Surgery 9, no. 2 (2021): 13–16. http://dx.doi.org/10.37506/ijocs.v9i2.3080.

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Probiotic is little known for its benefits on upper gastrointestinal health. The objective of this systematicreview was to examine the efficacy of probiotics in alleviating the frequency and severity of symptoms ingastroesophageal reflux disease (GERD) in the general adult population.. In total, 13 prospective studiesthat were published in 12 articles were included in the analysis and scored per the Jadad scale as high- (fivestudies), medium- (two), and low- (six) quality. One article reported on two probiotic groups; thus, 14comparisons were included in the selected studies, of which 11 (79%)

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Rosemurgy, Alexander, Harold Paul, Lauren Madison, et al. "A Single Institution's Experience and Journey with over 1000 Laparoscopic Fundoplications for Gastroesophageal Reflux Disease." American Surgeon 78, no. 9 (2012): 917–25. http://dx.doi.org/10.1177/000313481207800928.

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There have been great advances in laparoscopic surgery for gastroesophageal reflux disease (GERD), including laparoendoscopic single-site (LESS) surgery. This study details our experience with over 1000 patients undergoing fundoplication for GERD and the journey therein. A total of 1078 patients have been prospectively followed after fundoplication. Patients scored the frequency/severity of symptoms using a Likert scale (0 = never/not bothersome to 10 = always/very bothersome). We compared the outcomes of the first and last 100 patients. Median data are reported. Of 1078 patients, 943 underwen

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Asakura, Koji, Tomo Homma, Tsuyoshi Okuni, and Norikazu Yamazaki. "Globus Pharyngeus and Gastroesophageal Reflux-A Study with Frequency Scale for Symptoms of GERD-." Practica Oto-Rhino-Laryngologica 100, no. 6 (2007): 485–90. http://dx.doi.org/10.5631/jibirin.100.485.

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Yamamichi, Nobutake, Takeshi Shimamoto, Yu Takahashi, et al. "Trends in proton pump inhibitor use, reflux esophagitis, and various upper gastrointestinal symptoms from 2010 to 2019 in Japan." PLOS ONE 17, no. 6 (2022): e0270252. http://dx.doi.org/10.1371/journal.pone.0270252.

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The increasing usage of proton pump inhibitors (PPIs) has been reported worldwide, but information on PPI use in East Asia is inadequate. This study aimed to examine the trends in PPI use in Japan, along with the changes in histamine H2 receptor antagonist (H2RA) use, disease rate of reflux esophagitis, and the prevalence of upper gastrointestinal symptoms. We analyzed 217,712 healthy subjects (127,607 men and 90,105 women; 51.4 ± 9.7 years old) participating in the health check program from 2010 to 2019. Various upper gastrointestinal symptoms were evaluated using the frequency scale for the

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Dowgiałło-Gornowicz, Natalia, Anna Masiewicz, Justyna Kacperczyk, et al. "Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study." Medicina 58, no. 1 (2021): 47. http://dx.doi.org/10.3390/medicina58010047.

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Background and Objectives: Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases. It affects 20% of the adult population and is the third most common cause of chronic cough in adults. This study describes the results of LNF for the relief of GERD-related cough. Materials and Methods: The prospectively collected data on 135 laparoscopic LNF in our department from 2014 to 2018 were reviewed. During consultations, patients were asked about the frequency of symptoms using the GERD Impact Scale (GERD-IS), their satisfaction and recommendation to others, and thei

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Bakry, Salah, Sulten Al-Zahrani, Asem Rashed, Talal Alharthi, Suhayb Bakry, and Muhammad Siddiqui. "association of anxiety and depression among health specialties students with GERD in Makkah city, kingdom of Saudi Arabia (KSA). Cross-sectional study." Saudi Medical Horizons Journal 2, no. 2 (2022): 17–28. http://dx.doi.org/10.54293/smhj.v2i2.30.

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Introduction: The correlation between psychological factors and digestive abnormalities is significant yet, the full mechanism still undetermined. Objectives: Our study aimed to study the correlation between anxiety, depression, and GERD among health specialties students in Makkah city, Saudi Arabia (KSA). Methods: a survey-based study was demonstrated among health-related students in different medical colleges at Umm Al-Qura University in the period time between December 2020 until January 2021. GERD symptom frequency was evaluated using a previously validated gastroesophageal reflux symptom

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Takenaka, R., O. Matsuno, K. Kitajima, et al. "The use of frequency scale for the symptoms of GERD in assessment of gastro-oesophageal reflex symptoms in asthma." Allergologia et Immunopathologia 38, no. 1 (2010): 20–24. http://dx.doi.org/10.1016/j.aller.2009.06.005.

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Sadowitz, Benjamin D., Kenneth Luberice, Ty A. Bowman, et al. "A Single Institutions First 100 Patients Undergoing Laparoscopic Anti-Reflux Fundoplications: Where are They 20 Years Later?" American Surgeon 81, no. 8 (2015): 791–97. http://dx.doi.org/10.1177/000313481508100817.

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Although anti-reflux surgery has been used liberally over the past decades for the treatment of gastroesophageal reflux disease (GERD), few studies report follow-up after 10 years. This study was undertaken to report follow-up on 100 consecutive GERD patients up to 22 years after utilizing a laparoscopic fundoplication. Hundred consecutive patients undergoing laparoscopic fundoplication for GERD were prospectively followed beginning in 1992. The frequency and severity of symptoms before and after laparoscopic fundoplication were scored on a Likert scale (1 = never/none to 10 = always/very both

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Kusano, Motoyasu, Akiyo Kawada, Hiroko Hosaka, Yasuyuki Shimoyama, Shiko Kuribayashi, and Osamu Kawamura. "Sa1130 Modified Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease (FSSG) Distinguishes Functional Dyspepsia (FD) From Non-Erosive Reflux Disease (NERD)." Gastroenterology 142, no. 5 (2012): S—224. http://dx.doi.org/10.1016/s0016-5085(12)60838-5.

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Tassi, Valentina, Marialuisa Lugaresi, Benedetta Mattioli, et al. "FA02.03: TIMING OF REFLUX ESOPHAGITIS (RE) AND BARRET’S ESOPHAGUS (BE) DEVELOPMENT IN PATIENTS AFFECTED BY GERD AFTER HELLER MYOTOMY FOR ESOPHAGEAL ACHALASIA." Diseases of the Esophagus 31, Supplement_1 (2018): 3–4. http://dx.doi.org/10.1093/dote/doy089.fa02.03.

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Abstract Background In order to acquire data on development of RE and BE in patients affected by GERD after Heller myotomy, we investigated a group of these patients who had long term endoscopic follow up. Data acquired in this group and in a group of patients affected by primary GERD and BE were compared. Methods In 1973 our group established a research protocol and data base to include patients affected by esophageal diseases observed since 1955 and successively, who were followed up according to defined protocols. A semi quantitative Visick modified scale (RS0 absence; RS3 maximal severity)

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Shumilov, P. V., A. I. Khavkin, Yu A. Kucheryavy, et al. "Evaluation of esophagoprotective therapy for gastroesophageal reflux disease with extraesophageal symptoms in children and adolescents: results of an open-label, multicenter, observational study." Voprosy detskoj dietologii 20, no. 6 (2022): 6–13. http://dx.doi.org/10.20953/1727-5784-2022-6-5-13.

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Objective. To study the effect of esophagoprotector Alfasoxx on extraesophageal symptoms in children and adolescents with gastroesophageal reflux disease (GERD). Patients and methods. This article presents a prospective, open-label, multicenter, post-registration, observational study (the pediatric part of the EXTRASOXX protocol). The study enrolled 61 patients aged between 6 and 17 years (mean age: 12.5 ± 3.2 years) with a confirmed diagnosis of GERD who were prescribed a course of treatment with the esophagoprotector Alfasoxx (a combination of hyaluronic acid, chondroitin sulfate, and poloxa

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Fatani, Asmaa, Kadi Vaher, Karima Alabasi, and Wendy Dahl. "Fermented Soy Supplementation Improves Quality of Life Indicators: A Randomized, Placebo-Controlled, Double-Blind Trial in Adults Experiencing Heartburn." Current Developments in Nutrition 4, Supplement_2 (2020): 1124. http://dx.doi.org/10.1093/cdn/nzaa055_009.

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Abstract Objectives The aim of this pilot study was to determine the effects of a fermented soy supplement on heartburn relief, gastrointestinal symptoms, and quality of life. Methods A 5-week, randomized, double-blind pilot study was conducted with adults (n = 51; 37F/14 M, 31 ± 12y) experiencing mild or moderate heartburn. Following a 1-week baseline, participants self-treated heartburn symptoms with up to 3, 1 g sachets of a non-GMO soy flour fermented by Lactobacillus delbrueckii ssp. delbrueckii Rosell-187 or placebo (maltodextrin) sachets per incident for 3 weeks followed by a 1-week was

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