Dissertations / Theses on the topic 'Frey Twp'
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Morgan, J. D. "Codimension-two free boundary problems." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359484.
Full textGillow, Keith A. "Codimension-two free boundary problems." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298393.
Full textCAPRON, BARBARA ANNE. "TWO-PHOTON MULTIWAVE MIXING (DOPPLER-FREE SPECTROSCOPY)." Diss., The University of Arizona, 1986. http://hdl.handle.net/10150/183854.
Full textQiu, Shi. "Early exercise options with two free boundaries." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/early-exercise-options-with-two-free-boundaries(e19e1a9b-df0c-46e1-97f0-15cb1578689b).html.
Full textLindgren, Erik. "Regularity properties of two-phase free boundary problems." Doctoral thesis, KTH, Matematik (Inst.), 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-10336.
Full textQC 20100728
Kiel, David H. "Two nonlinear models of the Free Electron Laser." Thesis, Monterey, California. Naval Postgraduate School, 1990. http://hdl.handle.net/10945/30622.
Full textThe dynamics of the Free Electron Laser are governed by Maxwell's equations which causes many highly nonlinear regimes to exist in Free Electron Laser Physics. This thesis will examine two such areas and develop simple models to describe the highly dynamic and rich behavior two of these regimes. In the strong-field, high current regime, the Free Electron Laser driving current can be modeled by a single macroparticle representing the trapped electrons. When the trapped electrons act collectively as a macroparticle representing the trapped electrons. When the trapped electrons act collectively as a macroparticle, solutions which include synchrotron oscillations can be found for the self-consistent pendulum and wave equations. In an FEL oscillator with low single-pass gain, the evolution of the optical wave can lead to sideband development. This phenomenon is studied by applying Maxwell's equations to an oscillator with two optical modes and deriving a two-mode wave and pendulum equation. The two-mode wave and pendulum equations are implemented numerically on computers so that the onset of the sideband can be explored.
Konoplev, Ivan Vasilyevich. "Free-electron maser with two dimensional distributed feedback." Thesis, University of Strathclyde, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366827.
Full textSmith, Gregory J. "TOWARD A TWO-STAGE MODEL OF FREE CATEGORIZATION." CSUSB ScholarWorks, 2015. https://scholarworks.lib.csusb.edu/etd/234.
Full textKotík, David. "Implementace jednoduchého web serveru do mikrokontroléru ColdFire MCF 52233." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2009. http://www.nusl.cz/ntk/nusl-217778.
Full textAustvold, Stephen P. "Leading the Two Harbors Evangelical Free Church through the adjustment stage of the conflict cycle." Theological Research Exchange Network (TREN), 1991. http://www.tren.com.
Full textAlothman, Ahmad. "Model-Free Variable Selection For Two Groups of Variables." Diss., Temple University Libraries, 2018. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/515925.
Full textPh.D.
In this dissertation we introduce two variable selection procedures for multivariate responses. Our procedures are based on sufficient dimension reduction concepts and are model-free. In the first procedure we consider the dual marginal coordinate hypotheses, where the role of the predictor and the response is not important. Motivated by canonical correlation analysis (CCA), we propose a CCA-based test for the dual marginal coordinate hypotheses, and devise a joint backward selection algorithm for dual model-free variable selection. The second procedure is based on ordinary least squares (OLS). We derive and study the asymptotic properties of the OLS-based test under the normality assumption of the predictors as well as an asymmetry assumption. When these assumptions are violated, the asymptotic test with elliptical trimming and clustering is still valid with desirable numerical performances. A backward selection algorithm for the predictor is also provided for the OLS-based test. The performances of the proposed tests and the variable selection procedures are evaluated through synthetic examples and a real data analysis.
Temple University--Theses
Barros, Ricardo. "Gravity waves in two-layer flows with free surface." Aix-Marseille 3, 2007. http://www.theses.fr/2007AIX30080.
Full textIn this work we study the wave propagation in two-layer flows with free surface. Two distinct classes of models are contemplated. First, we consider the "two-layer" version of the shallow water equations (also known by Saint-Venant's equations). This model is strictly hyperbolic for small relative velocities. It would be natural to consider this model as suitable for the description of hydraulic jumps. However, like most of models describing multi-velocity flows, the system is not presented in conservative form. We present a survey on the number of conservation laws available for the multi-dimensional case that seems to imply that the system is truly nonconservative. Therefore, the impossibility of presenting a complete set of Rankine-Hugoniot conditions enabling the characterization of weak solutions in the classical way. Then, we obtain a dispersive model suited to the description of large amplitude waves propagating in the same physical system. The model is a "two-layer" generalization of the Green-Naghdi model and can be derived by applying Hamilton's principle to a Lagrangian that results from the insertion of approximations directly into the Lagrangian for the full waterwave problem. As a consequence, the variational structure of the original problem and the corresponding symmetry properties are preserved. In addition, it is a fully nonlinear model and deals with rotational flows. As in the case of the full problem, the present model captures the resonance between short waves and long waves. In this framework it is shown, by using numerical computations, the existence of homoclinic trajectories embedded into the continuous spectrum. These correspond to true solitary waves having the same velocities at infinity in each layer. Their study reduces to the analysis of a Hamiltonian system with two degrees of freedom. The traveling-wave solutions depend on three parameters : the density ratio, the depth ratio and the Froude number based on the bottom layer. Two wave regimes, characterized by the elevation or depression of the interface between the layers are presented. A critical depth ratio separates these two regimes and it will be shown how it relates to a change of the structure of the potential for the Hamiltonian system. The analysis of the number and nature of critical points turned out to be decisive in this work. It was found that the number of critical points can be four or two, depending on the value of the Froude number (for fixed density and depth ratios). For sets of parameters corresponding to oceanic conditions we have perceived the existence of true solitary waves and their broadening whenever the wave speed increases towards a limit value. Finally, other sets of parameters are considered for which multi-humped solitons exist, highlighting the richness and complexity of the system considered
Botcherby, Edward J. "Aberration free extended depth of field microscopy." Thesis, University of Oxford, 2007. http://ora.ox.ac.uk/objects/uuid:7ad8bc83-6740-459f-8c48-76b048c89978.
Full textNandkumar, Subhash. "Two-stroke linear engine." Morgantown, W. Va. : [West Virginia University Libraries], 1998. http://etd.wvu.edu/templates/showETD.cfm?recnum=153.
Full textTitle from document title page. Document formatted into pages; contains x, 82 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 69-70).
Kinjo, Tomoaki. "FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics." Kyoto University, 2020. http://hdl.handle.net/2433/253137.
Full textMorgan, Edward Dylan. "Three Essays on Environmental Economics: Subsidies, Free Riding, and Public Shaming." Thesis, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31710.
Full textChung, Derrick Kin Hank 1980. "Equations of one and two variables over a free group." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=81273.
Full textMao, Wenqun. "Numerical simulation of transient viscoelastic flows with two free surfaces." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=68212.
Full textMunther, Daniel S. "Ideal Free Dispersal: Dynamics of Two and Three Competing Species." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1312904354.
Full textHeitzman, Michael Thomas Chicone Carmen Charles. "A free boundary gas dynamic model as a two-body field theory problem." Diss., Columbia, Mo. : University of Missouri--Columbia, 2009. http://hdl.handle.net/10355/7017.
Full textAyliffe, Michael H. "Alignment and packaging techniques for two-dimensional free-space optical interconnects." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=37866.
Full textThis thesis proposes a broad range of solutions to alleviate this alignment problem. One important aspect of this work concerns the development of a generic packaging strategy, which consists of partitioning an optical system into separate modules in such a way that the loose tolerances are between the modules while the tight tolerances are between the components inside the modules. To accomplish this, novel alignment techniques are designed and demonstrated, including the use of integrated diffractive features, CMOS position detectors, ultrathick photoresist micro-structures, and semi-kinematic fixtures using dowel pins. In all cases, emphasis is placed on approaches that are amenable to low-cost manufacturing and high-volume production.
These techniques were developed in the context of a photonic backplane prototype experiment that demonstrated 1024 free-space interconnections between four optoelectronic-VLSI (OE-VLSI) chips. The design and implementation of a module integrating an OE-VLSI chip, a mini-lens array, a thermoelectric cooler and a heatsink is presented. Optomechanical, electrical and thermal characterization results are reported.
The other aspect of this work aims at identifying the types of optical designs that provide more generous misalignment tolerances. This is done by investigating various optical configurations for the design of the chip module. The central objective is to understand the underlying reasons that make one configuration more misalignment-tolerant than another. A significant outcome of this work is to show that the inherent misalignment tolerances of 2D-FSOI systems translates into an aspect-ratio limitation similar to the one found in electrical interconnects.
King, Andrew. "Claw-free graphs and two conjectures on omega, Delta, and chi." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=66861.
Full textCette thèse a pour sujet la relation entre quatre invariants de graphes : omega, chi_f, chi, et Delta.Il s'agit respectivement du nombre de clique, du nombre chromatique fractionnaire,du nombre chromatique, et du degré maximum. Ces paramètres vérifient trivialementl'encadrement suivant : omega <= chi_f <= chi <= Delta+1, dans lequel on cherche ça améliorerla borne supérieure sur chi. Une des principales motivations pour ce travail est uneconjecture de Reed, qui dit essentiellement que chi est au plus la moyenne de ses bornesinférieures et supérieures triviales.Conjecture. Pour tout graph, chi <= (Delta + 2 + omega)/2.On appelle cet énoncé la Conjecture Principale, et on propose un RenforcementLocal basé sur le voisinage de chaque sommet.Conjecture. Pour tout graphe G, chi <= max{v dans V(G)} (d(v) + 2 + omega(G[N(v)]) + 1) / 2.On commence par montrer que la plupart des arguments en faveur de la ConjecturePrincipale incitent également à croire que le Renforcement Local est vrai. Enparticulier, la borne donnée par le Renforcement Local vaut pour chi_f et le RenforcementLocal peut être montré lorsque le nombre de stabilité vaut deux.Guidé par ces premiers pas, on s'intéresse aux graphes adjoints, pour lesquels chi_fet chi sont asymptotiquement équivalents. On montre la Conjecture Principale dansle cas des graphes adjoints et on cherche ensuite à généraliser ce résultat.Pour cela on utilise des résultats récents de Chudnovsky et Seymour, qui ontcaractérisé la structure les graphes sans griffes. On affine ces résultats en introduisantla notion de graphes squelettes. Dans les problèmes auxquels on s'intéresse,on peut facilement se ramener au cas des graphes squelettes, et la structure desgraphes squelettes sans griffes est plus simple que celle des graphes sans griffes engénéral.On étend deux résultats des graphes adjoints aux graphes quasi-adjoints : onmontre que la Conj
Châteauneuf, Marc. "Design and alignment methodologies for two-dimensional free-space optical interconnects." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=19655.
Full textLee, Wing Kuen. "Interpreting tables in text using probabilistic two-dimensional context-free grammars /." View abstract or full-text, 2005. http://library.ust.hk/cgi/db/thesis.pl?COMP%202005%20LEEW.
Full textCord, Gregory A. "Free electron laser short pulse simulation and two-mode sideband analysis." Thesis, Monterey, California. Naval Postgraduate School, 1991. http://hdl.handle.net/10945/28234.
Full textMay, Andrew J. "A Comparison of the Effectiveness of Two Free Throw Shooting Methods." BYU ScholarsArchive, 2011. https://scholarsarchive.byu.edu/etd/2918.
Full textHull, Jesse F. "Recognition of mathematics using a two-dimensional trainable context-free grammar." Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/10587.
Full textIncludes bibliographical references (leaves [100]-101).
by Jesse F. Hull.
M.Eng.
Nord, Iza. "Reducing Greenhouse Gas Emissions Through the Use of Free Shops : A Case Study of Two Free Shops in Gothenburg." Thesis, Mittuniversitetet, Avdelningen för ekoteknik och hållbart byggande, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-33920.
Full text20180625
Kaganovskii, Yuri, Lyudmila N. Paritskaya, and Valeriy V. Bogdanov. "Lateral diffusion spreading of two competitive intermetallic phases along free surface (system Cu-Sn): Lateral diffusion spreading of two competitive intermetallicphases along free surface (system Cu-Sn)." Diffusion fundamentals 6 (2007) 43, S. 1-2, 2007. https://ul.qucosa.de/id/qucosa%3A14219.
Full textViana, MartÃnio Ponte. "ToxicoproteÃmica aplicada à anÃlise de risco da proteÃna recombinante cry1ac de Bacillus thuringiensis." Universidade Federal do CearÃ, 2014. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=17262.
Full textCoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior
Dentre os vÃrios microrganismos entomopatogÃnicos utilizados no controle biolÃgico, o Bacillus thuringiensis (Bt) vem sendo considerado uma das alternativas mais viÃveis, devido à presenÃa de proteÃnas inseticidas em seus esporos, como as δ-endotoxinas Cry. As toxinas Cry apresentam atividade contra diferentes ordens de insetos, como Coleoptera, Diptera, Hymenoptera, Hemiptera e Lepidoptera. Tais proteÃnas sÃo altamente especÃficas, ou seja, sÃo inÃcuas para a maioria dos organismos nÃo-alvo, fato que favorece sua utilizaÃÃo na agricultura. Hoje existem mais de 114 milhÃes de hectares de lavouras geneticamente modificadas e 37% expressam traÃos de proteÃnas inseticidas de Bt. Como os organismos geneticamente modificados (OGMs) estÃo se tornando cada vez mais predominantes, vÃrias organizaÃÃes internacionais tÃm dado orientaÃÃes no sentido de investigar a seguranÃa de alimentos provenientes de OGMs. Este trabalho teve como objetivo utilizar uma abordagem toxicoproteÃmica para anÃlise de risco da proteÃna recombinante Cry1Ac de Bt a fim de contribuir para uma maior compreensÃo de seus efeitos em modelo de mamÃferos. O ensaio de toxicidade foi conduzido de acordo com o protocolo 425 da âOrganizaÃÃo para a CooperaÃÃo e Desenvolvimento EconÃmicoâ - OECD e nÃo foram verificadas mortes ou sinais de toxicidade. As anÃlises proteÃmicas baseadas em gel mostraram 4 proteÃnas diferencialmente expressas Serpina α-1, Serpina A3K, CininogÃnio e Complemento C3. Essas proteÃnas tiveram uma reduÃÃo em sua expressÃo no grupo tratado com a toxina Cry1Ac. Na abordagem âgel-freeâ foram identificadas 7 proteÃnas diferencialmente expressas. Dentre elas, fator I, inibidor de tripsina H3, plasminogÃnio, serpina A6, albumina e proteÃna resistente à oxidaÃÃo apresentaram uma expressÃo maior em animais tratados com Cry1Ac, enquanto que a protrombina teve sua expressÃo reduzida em animais tratados com a mesma proteÃna. Tais molÃculas sÃo importantes para hemostasia e sistema imune, podendo interferir no processo inflamatÃrio, na ativaÃÃo da via do complemento e da cascata de coagulaÃÃo. No entanto, a abordagem toxicoproteÃmica adotada mostra-se Ãtil para a identificaÃÃo de efeitos adversos, atà mesmo de uma jà amplamente conhecida por sua baixa toxicidade. Isso encoraja a utilizaÃÃo da referida abordagem para a avaliaÃÃo de risco de proteÃnas recombinantes. Apesar das alteraÃÃes fisiolÃgicas causadas, a proteÃna Cry1Ac ainda à considerada segura jà que tais alteraÃÃes ocorreram na dose mais alta recomenda pela OECD (2000mg/Kg) e sem causar morte dos animais.
Among the various pathogenic bacteria used in biological control, Bacillus thuringiensis has been considered one of the most viable alternatives, due to the presence of insecticidal proteins in their spores, such as the δ-endotoxin, Cry. The Cry toxins exhibit activity against different insect orders, such as Coleoptera, Diptera, Hymenoptera, Hemiptera and Lepidoptera. Such proteins are highly specific, which means, they are harmless to most organisms. This fact justifies their use in agriculture. Nowadays, there are over 114 million hectares of GM crops and 37% express traits of insecticidal proteins of B. thuringiensis. Since genetically modified organisms (GMOs) are becoming increasingly prevalent, several international organizations have given guidelines to investigate the safety of food derived from GMOs. This work aimed to evaluate the acute toxicity of the entomotoxin Cry1Ac in rats through classical in vivo analyzes associated with proteomic study by two-dimensional electrophoresis and shotgum proteomic technique (gel-free). Toxicity tests were conducted according to the protocol of 425 "Organization of Economic Cooperation and Development" - OECD and no deaths or signs of toxicity were observed. The gel-based proteomic analysis showed four differentially expressed proteins: Serpin α-1, Serpin A3K, Kininogen and Complement C3. These proteins expressions were reduced for the group treated with the Cry1Ac toxin. In gel-free approach, seven differentially expressed proteins were identified. Among them, factor I, H3 trypsin inhibitor, plasminogen, serpin A6, albumin, and protein resistant to oxidation showed a higher expression in animals treated with Cry1Ac, while the prothrombin expression was reduced in animals treated with the same protein. Such molecules are important for hemostasis and immune system, and may interfere with the inflammatory process, activation of the complement pathway and the coagulation cascade. Despite the physiological changes caused by Cry1Ac, this protein is still considered safe since these changes occurred at the highest dose recommended by OECD (2000 mg / kg) and without causing death of the animals.
Ponraj, Sathishkumar. "Stimulus-free RT level power model using belief propagation." [Tampa, Fla.] : University of South Florida, 2004. http://purl.fcla.edu/fcla/etd/SFE0000531.
Full textHoudyschell, David. "A diesel two-stroke linear engine." Morgantown, W. Va. : [West Virginia University Libraries], 2000. http://etd.wvu.edu/templates/showETD.cfm?recnum=1312.
Full textTitle from document title page. Document formatted into pages; contains ix, 64 p. : ill. (some col.) Includes abstract. Includes bibliographical references (p. 42-43).
Frey, Tanja [Verfasser], and Mathias [Akademischer Betreuer] Ritzmann. "Wirksamkeit einer two-shot Vakzine nach experimenteller Infektion von Endmastschweinen mit Mycoplasma hyopneumoniae / Tanja Frey. Betreuer: Mathias Ritzmann." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2014. http://d-nb.info/1053618476/34.
Full textYilmaz, Burak. "Development And Validation Of Two-dimensional Depth-averaged Free Surface Flow Solver." Master's thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/1089523/index.pdf.
Full textGhamry, Haitham Kamal. "Two-dimensional vertically averaged and moment equations for shallow free-surface flows." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0026/NQ39531.pdf.
Full textLiu, Bo Yan. "Two-dimensional free vibration analysis of cracked FGM beams by Ritz method." Thesis, University of Macau, 2015. http://umaclib3.umac.mo/record=b3335682.
Full textPersaud, Michael Alan. "Doppler-free two-photon spectroscopy of one electron atoms using pulsed lasers." Thesis, University of Southampton, 1991. https://eprints.soton.ac.uk/361600/.
Full textMeyers, David Morton. "Freak beer (Part two - Do not resuscitate)." Thesis, University of Iowa, 2019. https://ir.uiowa.edu/etd/6805.
Full textAkinbohun, Olugbenga John. "To ascertain why some women delay in seeking termination of pregnancy (TOP) for unwanted pregnancies in Lejweleputswa District (DC18), Free State." Thesis, University of the Western Cape, 2005. http://etd.uwc.ac.za/index.php?module=etd&.
Full textRegardless of the availability of choice of TOP, some pregnant women still present late (after 12 weeks) for TOP when the risks of complications and costs are higher. Women who present late for TOP usually have to be admitted to a district or regional hospital and managed. The costs at such institutions are high. TOPs before 12 weeks (early TOP) are done in a primary health care (PHC) facility (TOP center) and no admission is required hence less cost. Complications of early TOP are also very mild and rare. In Lejweleputswa district there is only one TOP Center (Kopano TOP Clinic) and this serves both Lejweleputswa and the Northern Free State districts. Early TOPs (less than 12 weeks) are done and completed at this center. Late TOPs (above 12 weeks but not more than 20 weeks) are initiated at this TOP center and referred to district or regional hospitals nearest to the patient&rsquo
s home, in both districts for completion.
Problems - An increasing number of women are seeking TOP service at late stages of pregnancies and the incidence of severe complications like severe bleeding, retained placenta, infection, amniotic fluid embolism, death etc, are increasing. The hospital&rsquo
s bed space and budget are stretched to the limit due to the influx of late term TOP to the hospitals. Lack of manpower, especially doctors, in these hospitals also create some problems, as the few doctors available have to attend to other ill patients as well. Sometimes bleeding TOP patients are transfused with blood and placed on a waiting list for theatre and this often increases the risk of complications. The emotional effect of late TOP on hospital staff (doctors and nurses) are enormous as the expelled fetus are much more developed than in early TOP where no fetus is seen at evacuation with simple Manual Vacuum Aspiration (MVA).
Yamamoto, Shinya. "Spatiotemporal ATP Dynamics during AKI Predict Renal Prognosis." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263351.
Full textVahlroos, Riikka. "I began to be free : A study on two trans-active Finnish men." Thesis, Linköping University, Department of Culture and Communication, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-16686.
Full textThis study focuses on Finnish transmen and their life stories. It goes through the practical reality of the gender re-assignment process, but focuses on the personal experiences of two individual men. The study is based on in-depth interviews with informants, material which has been analyzed with the help of Judith Butler’s theory on gender.
Den här uppsatsen handlar om två finska transmän och deras livshistorier. Studien går igenom den praktiska realiteten av könskorrigeringsprocessen, men fokuserar på de personliga erfarenheterna av dessa två individuella män. Den är baserad på djupintervjuer med informanter, material som har analyserats med hjälp av Judith Butlers teori om genus.
Elborai, Shihab M. (Shihab Mahmoud) 1977. "Operation and control of a two-stroke, free-piston-engine-driven linear alternator." Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/86476.
Full textIncludes bibliographical references (p. 126).
by Shihab M. Elborai.
S.B.and M.Eng.
Zanet, Phillip. "Characterization of two novel cysteine proteases in the free-living organism «Macrostomum ligano »." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119584.
Full textL'objectif de cette recherche était d'explorer l'organisme, vivant en liberté dans la nature, Macrostomum lignano en tant qu'organisme modèle pour ses cousins parasites, Fasciola et Schistosoma, et de mieux comprendre le rôle de leurs protéases cystéines (cathepsins). En utilisant une approche bioinformatique, deux nouveaux gènes de protéases cystéines (mlcl1 et mlcb2) ont été découverts et caractérisés phylogénétiquement. Ces gènes ont été synthétisés, clonés dans un système de sécrétion employant la levure Pichia pastoris (Invitrogen) et exprimés en tant que protéases recombinantes et actives. Ces protéases recombinantes ont alors été caractérisées biochimiquement en termes d'activité et de stabilité dans diverses conditions telles que la température, la salinité et le pH. Des anticorps spécifiques aux protéines recombinantes ont été générés en immunisant des mammifères avec des séquences de peptides ou la protéine recombinante entière, et ont été testés avec l'extrait du vers prouvant ainsi que les protéines sont bel et bien exprimées. Ces études jettent la base pour l'investigation sur la fonction biologique des protéases cystéines par l'emploi du RNAi et de la microscopie confocale. En conclusion, M. lignano est un organisme modèle tractable pour ses cousins parasites.
Alexis, naza. "Corrosion behavior of lead-free and dezincification resistant brass alloys in tap water." Thesis, KTH, Kemi, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-299738.
Full textDezincification resistant (DZR) and lead-free brass alloys continue to be widely applied replacing lead containing brasses in the drinking water sector. Due to the limited number of corrosion studies of these alloys in tap water, the present thesis was initiated with the aim to understand how the water type, its temperature and exposure duration can affect the corrosion behavior. Three DZR brass alloys were studied in order to evaluate their corrosion behavior in tap water of varying characteristics. The alloys included were two lead-free brasses (CW511L and CW724R) and a leaded brass alloy (CW602N) considered as a reference material. A combination of electrochemical, microscopic and surface analytical techniques were adopted to explore the corrosion form, mechanisms and corrosion rate. While these alloys passed the dezincification test as per ISO 6509-1:2014, the aim was to assess their corrosion performance in tap water. The influence of water chemistry parameters including pH, chloride concentration and alkalinity on the corrosion resistance of the three DZR alloys was investigated in short-term exposures (24 h). Depending on the brass alloy, the corrosivity of the test waters varied. The results show grade CW511L to be more sensitive in tap water of higher chloride concentration (44.7 mg/L) and alkalinity (310 mg/L) compared with low pH (6.9). However, opposite results were obtained for both CW724R and CW602N. The corrosivity of the test water was also affected by the temperature when increased from 22°C to 50°C during 24 h of immersion. While no dezincification features were observed on the surfaces, a combination of general and localized corrosion was observed to a largely variable extent between the alloys. The extent of initiation of localized corrosion varied with test water and alloy composition. While CW724R and CW602N showed similar high susceptibility to localized corrosion in the alkaline (pH 8.2) tap water, CW511L was more prone to pitting corrosion in tap water of low pH (6.9). The effect of exposure duration was explored in the alkaline test water for the three brasses up to 72 days. Corrosion rates based on weight loss showed an expected initial high corrosion rate which declined with continuous immersion, leading to low and similar corrosion rates for all three brass alloys after 72 days. Thus, at given test conditions, the lead-free brasses showed good corrosion behavior being competitive to the performance of lead containing brass. Therefore, lead-free brass alloys are good candidates to substitute lead-containing brasses in tap water applications.
Rasadurai, Rajavaheinthan. "Forced water entry and exit of two-dimensional bodies through a free surface." Thesis, Brunel University, 2014. http://bura.brunel.ac.uk/handle/2438/8327.
Full textPagden, Louise. "Free school Policy Enactment in two case-study schools : motivation, vision and reality." Thesis, University of Reading, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.701639.
Full textJonsson, Karl. "Two Problems in non-linear PDE’s with Phase Transitions." Licentiate thesis, KTH, Matematik (Avd.), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-223562.
Full textQC 20180222
Olsson, Elin. "Mass Conserving Simulations of Two Phase Flow." Licentiate thesis, Stockholm, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3851.
Full textOlszak, Peter D. "Nonlinear absorption and free carrier recombination in direct gap semiconductors." Doctoral diss., University of Central Florida, 2010. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/4620.
Full textID: 029050684; System requirements: World Wide Web browser and PDF reader.; Mode of access: World Wide Web.; Thesis (Ph.D.)--University of Central Florida, 2010.; Includes bibliographical references.
Ph.D.
Doctorate
Optics and Photonics
Coppola, Owen Herbert. "A Finite Element Model for Free Surface and Two Fluid Flows on Fixed Meshes." Doctoral thesis, Universitat Politècnica de Catalunya, 2009. http://hdl.handle.net/10803/5913.
Full textSe usa un método de elementos finitos de malla fija, donde la posición de interfaz es capturada por la función de Level Set. Los flujos a bajo número de Froude son particularmente desafiantes para los métodos de malla fija. Una representación precisa es necesaria en los elementos cortados por el frente. Se proponen dos alternativas.
La primera alternativa usa el modelo de flujo de dos fases típico, enriqueciendo las funciones de forma de presión, para permitir una mejor aproximación de la discontinuidad en el gradiente de presión en la interfaz. La mejora de la representación del gradiente de presión es el ingrediente clave para el correcto modelado de tales flujos.
La influencia del segundo fluido puede ser ignorada en una amplia variedad de aplicaciones para terminar con un modelo de superficie libre que es más simple que el modelo de flujo de dos fases. La discontinuidad en el gradiente de presión desaparece porque sólo se simula un fluido. La particularidad de este segundo método es que se usa una malla fija. Las condiciones de contorno son aplicadas exactamente usando integración mejorada e integrándose sólo en la parte llena de los elementos cortados por el frente. Se desarrolla un método ALE de malla fija para tener en cuenta correctamente que el dominio se mueve a pesar de que se usa una malla fija. Los métodos de segregación de presión son explorados como una alternativa a la discretización monolítica de las ecuaciones de Navier Stokes. Ellos desacoplan las incógnitas de velocidad y presión, conduciendo a subproblemas más pequeños y mejor condicionados. Los métodos de corrección de presión y corrección de velocidad son presentados y comparados numéricamente. Usando un Laplaciano discreto se obtiene un método de corrección de velocidad de tercer orden numéricamente estable.
Los métodos son aplicados a problemas de llenado de moldes tridimensionales tomados directamente de la fundición con resultados muy satisfactorios. El modelo monolítico con superficial libre resulta ser la opción más robusta y eficiente. La comparación con un código comercial muestra la exactitud y la eficacia del método que proponemos.
Flows with moving interfaces (free surface and two-fluid interface problems) appear in numerous engineering applications. The methods presented in this thesis are oriented mainly to the simulation of mould filling process. Nevertheless the methodology is sufficiently general as to be applied to most free surface and two-fluid interface flows. Numerical modeling provides an efficient way of analyzing the physical phenomena that occur during casting and injection processes. It gives insight into details of the flow that would otherwise be difficult to observe.
A fixed mesh finite element method, where the interface position is captured by the Level Set function, is used. Low Froude number flows are particularly challenging for fixed grid methods. An accurate representation is needed in the elements cut by the interface for such flows. Two alternatives are proposed.
The first alternative is to use the typical two-phase flow model enriching the pressure shape functions so that the discontinuity in the pressure gradient at the interface can be better approximated. The improvement in the representation of the pressure gradient is shown to be the key to ingredient for the successful modeling of such flows.
The influence of the second fluid can be neglected on a wide range of applications to end up with a free surface model that is simpler than the twophase flow model. The discontinuity in the pressure gradient disappears because only one fluid is simulated. The particularity of this second approach is that a fixed mesh is used. Boundary conditions are applied accurately using enhanced integration and integrating only in the filled part of cut elements.
A fixed mesh ALE approach is developed to correctly take into account that the domain is moving despite a fixed mesh is used.
Pressure segregation methods are explored as an alternative to the monolithic discretization of the Navier Stokes equations. They uncouple the velocity and pressure unknowns, leading to smaller and better conditioned subproblems.
Pressure correction and velocity correction methods are presented and compared numerically. Using a discrete Laplacian a numerically stable third order velocity correction method is obtained.
The methods are applied to three dimensional mould filling problems borrowed directly from the foundry with very satisfactory results. The free surface monolithic model turns out to be the most robust and efficient option. The comparison with a commercial code shows the accuracy and efficiency of the method we propose.