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1

Farnworth, E. R., H. W. Modler, J. D. Jones, N. Cave, H. Yamazaki, and A. V. Rao. "Feeding Jerusalem artichoke flour rich in fructooligosaccharides to weanling pigs." Canadian Journal of Animal Science 72, no. 4 (December 1, 1992): 977–80. http://dx.doi.org/10.4141/cjas92-112.

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Weaned pigs were fed a control diet or one containing 1.5% Jerusalem artichoke tuber flour (JAF) containing fructooligosaccharides or 1.5% Neosugars (NS) for 4 wk. Experimental parameters, including feed intake, body-weight gain, feed efficiency, digesta volatile fatty acid levels and microbiological profile were not significantly affected by diet. Key words: Jerusalem artichoke, fructooligosaccharide, bifidobacteria
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2

Yıldız, S. "The Metabolism of Fructooligosaccharides and Fructooligosaccharide-Related Compounds in Plants." Food Reviews International 27, no. 1 (September 2010): 16–50. http://dx.doi.org/10.1080/87559129.2010.518295.

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3

Dimov, Ivica, Mariya Choneva, Ilia lliev, and Anelia Bivolarska. "EFFECT OF OLIGOSACCHARIDES ON ENZYMES OF CARBOHYDRATE METABOLISM AND ANTIOXIDANT PROTECTION IN IN VITRO TREATED ERYTHROCYTES UNDER CONDITIONS OF HYPERGLYCEMIA." Journal of IMAB - Annual Proceeding (Scientific Papers) 27, no. 4 (December 9, 2021): 4143–50. http://dx.doi.org/10.5272/jimab.2021274.4143.

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Introduction: The purpose of this experiment is to examine the effect of different oligosaccharides with proven prebiotic effects on enzymes of carbohydrate metabolism and the antioxidant protection of erythrocytes in vitro under conditions of hyperglycemia. Materials and methods: This experiment included 10 healthy men (27±3 years of age). The isolated erythrocytes were treated with 1% and 5% solutions of the following oligosaccharides: lactulose, inulin, galactooligosaccharide and fructooligosaccharide in the presence of 5mM, 50mM and 100mM glucose. After incubation, for 2 hours at 37 °C, the erythrocytes were lysed, and the supernatant was used for analyses of lactate dehydrogenase, hexokinase and glutathione reductase. FRAP (Ferric reducing antioxidant power) method was used for determining the total antioxidant activity of erythrocytes. Results: Lactate dehydrogenase was decreased in the presence of 5% lactulose in groups with 50mM and 100 mM Glc. An increase in the activity of glutathione reductase under severe hyperglycemia (100mM glucose) was observed after treatment with: 1% lactulose, 1% inulin, 1% galactooligosaccharide, 1% and 5% fructooligosaccharides (p<0.005). A significant difference in the enzymatic activity of hexokinase was found in all groups (p<0.05) and of glutathione reductase only in the control group as well as in the groups treated with 1% lactulose, 1% galactooligosaccharide, 1% and 5% fructooligosaccharides Conclusions: Galactooligosaccharides 1% and fructooligosaccharides 1% and 5% cause a statistically significant increase of the enzymatic activities of hexokinase and glutathione reductase in in vitro hyperglycemia induced by 100 mM glucose, as well as an increase in FRAP.
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4

Korczak, Renee, and Joanne L. Slavin. "Fructooligosaccharides and appetite." Current Opinion in Clinical Nutrition & Metabolic Care 21, no. 5 (September 2018): 377–80. http://dx.doi.org/10.1097/mco.0000000000000502.

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5

Deffert, Flávia, Bruna Carla Agustini, Geraldo Picheth, and Tania Maria Bordin Bonfim. "Screening of whole yeast free-cells and optimization of pH and temperature for fructooligosaccharides production." Acta Scientiarum. Biological Sciences 39, no. 2 (June 16, 2017): 189. http://dx.doi.org/10.4025/actascibiolsci.v39i2.34140.

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Fructooligosaccharides are catalyzed by β–fructofuranosidase enzyme, produced by many microorganisms. However, in order to achieve a more profitable, low time-consuming process with lower cost, researchers have sought alternatives. This study aimed to select and identify yeasts able to produce fructooligosaccharides and evaluate the influence of pH and temperature on their synthesis. Yeast suspensions, solutions of 500 g L-1 sucrose and three values of pH (4.5, 5.5, and 6.5) and temperature (40, 50, and 60ºC) were tested. Yeast species were identified by molecular techniques. Among 141 yeast isolates from grapes, 65 were able to synthesize fructooligosaccharides. The maximum concentration of fructooligosaccharides was 4.8% (w v-1), and Saccharomyces cerevisiae 222 produced 1-kestose and nystose.
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Kang, Sini, Hyun Ju You, Ying Ju, Hee Jung Kim, Yun Ju Jeong, Tony V. Johnston, Geun Eog Ji, Seockmo Ku, and Myeong Soo Park. "Butyl-fructooligosaccharides modulate gut microbiota in healthy mice and ameliorate ulcerative colitis in a DSS-induced model." Food & Function 13, no. 4 (2022): 1834–45. http://dx.doi.org/10.1039/d1fo03337a.

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Butyl-fructooligosaccharides (B-FOSs) are synthetic molecules designed to combine the biofunctionalities of butyrate and fructooligosaccharides (FOSs), which solve the difficulty with oral butyrate delivery.
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7

Campagnol, Paulo Cezar Bastianello, Bibiana Alves dos Santos, José Manuel Lorenzo, and Alexandre José Cichoski. "A combined approach to decrease the technological and sensory defects caused by fat and sodium reduction in Bologna-type sausages." Food Science and Technology International 23, no. 6 (March 26, 2017): 471–79. http://dx.doi.org/10.1177/1082013217701859.

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The effect of the addition of fructooligosaccharides, transglutaminase, disodium inosinate, and disodium guanylate on some technological and sensory parameters of low-fat and low-salt Bologna-type sausages was evaluated. In the first experiment, sausages with a 25% and 50% fat reduction containing 0, 3%, or 6% fructooligosaccharides were manufactured. Fat reduction adversely affected the emulsion stability, hardness, and sensory properties; however, the addition of 6% fructooligosaccharides reduced the loss of quality associated with a lower fat content. In the second experiment, sausages with a 50% fat reduction containing 6% fructooligosaccharides were produced. Additionally, the salt content was reduced by 50% and transglutaminase, disodium inosinate, and disodium guanylate were added. The combination of transglutaminase (1%), disodium inosinate (0.03%), and disodium guanylate (0.03%) was efficient to supress the technological and sensory defects caused by NaCl reduction in low-fat Bologna-type sausages.
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8

Bhadra, Sushruta, Dixita Chettri, and Anil Kumar Verma. "Microbes in fructooligosaccharides production." Bioresource Technology Reports 20 (December 2022): 101159. http://dx.doi.org/10.1016/j.biteb.2022.101159.

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9

Kherade, Monika, Sohani Solanke, Mukund Tawar, and Sagar Wankhede. "Fructooligosaccharides: A comprehensive review." Journal of Ayurvedic and Herbal Medicine 7, no. 3 (September 30, 2021): 193–200. http://dx.doi.org/10.31254/jahm.2021.7305.

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Fructooligosaccharides (composed of short fructose chains) are useful for a variety of purposes. They are a type of carbohydrate known as oligosaccharides. Nowadays, people around the world are much more health-conscious and expect the food they consume to be tasty, safe as well as healthy. Fructooligosaccharides have become a prominent player in the functional food industry because of the growing demand for healthy and quality food. Due to its functional properties and health benefits, it is incorporated in various products like Dairy products, Bakery products, Beverages and Juices, Jams and Jellies, Candies, Chocolates, Breakfast cereals, Meat products, Ice cream, Confectionery. This article aims to review the numerous plant sources of Fructooligosaccharides available in nature, its structure, production, mode of action, attention-grabbing properties as well as their application as food ingredients, with special attention is being paid to the health benefits of these compounds.
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10

Silva, Karen Cristina Guedes, and Ana Carla Kawazoe Sato. "Biopolymer gels containing fructooligosaccharides." Food Research International 101 (November 2017): 88–95. http://dx.doi.org/10.1016/j.foodres.2017.08.042.

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11

Natasya, Nur Wanda Aini, and Prima Retno Wikandari. "Pengaruh Lama Fermentasi Umbi Gembili (Dioscorea esculenta L.) dengan Kultur Starter Lactobacilus plantarum B1765 Terhadap Produksi Fruktooligosakarida." Unesa Journal of Chemistry 11, no. 2 (July 1, 2022): 88–96. http://dx.doi.org/10.26740/ujc.v11n2.p88-96.

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Abstract. Fructooligosaccharides (FOS) are additives that are often used and utilized in the food, pharmaceutical, and chemical industries that have functional value for health. Lactobacillus plantarum B1765 has been known to have inulinase activity. This research aimed to further explore the potential of L.plantarum B1765 in the production of FOS from lesser yam tuber inulin by looking at the total growth of lactic acid bacteria (LAB) and the degree of polymerization (DP) during a certain fermentation time. The duration of fermentation was carried out for 24, 48, and 72 hours. The testing of Total LAB using total plate count (TPC) method with MRS Agar medium. The Testing determination of total sugar and reduction sugar using the Nelson Somogyi method. Determination of the degree of polymerization (DP) of the formed FOS is based on the result of dividing the total sugar formed with the reducing sugar released during the fermentation process. The results of total LAB that grows from each fermentation time is 2,11×107; 1,55 ×108; and 3,3 ×109 CFU/mL, with degree of polymerization formed from each fermentation time are 3,470; 2,286; and 1,740. Comercial FOS has a DP value of 3-5. This study was able to produce a commercially acceptable fructooligosaccharide with a DP of 3,470, which could be used for industrial development of fermented lesser yam tuber fructooligosaccharides. Key words: Lactobacillus plantarum B1765, lesser yam tuber, inulin, FOS, degree of Polymerization
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12

Guio, Felipe, Mauro Rodriguez, Carlos Almeciga-Diaz, and Oscar Sanchez. "Recent Trends in Fructooligosaccharides Production." Recent Patents on Food, Nutrition & Agriculturee 1, no. 3 (November 1, 2009): 221–30. http://dx.doi.org/10.2174/2212798410901030221.

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13

Guio, Felipe, Mauro A. Rodriguez, Carlos J. Almeciga-Diaz, and Oscar F. Sanchez. "Recent Trends in Fructooligosaccharides Production." Recent Patents on Food, Nutrition & Agriculture 1, no. 3 (January 9, 2010): 221–30. http://dx.doi.org/10.2174/1876142910901030221.

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14

Tokunaga, Takahisa. "Novel physiological function of fructooligosaccharides." BioFactors 21, no. 1-4 (2004): 89–94. http://dx.doi.org/10.1002/biof.552210117.

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15

Yun, Jong Won. "Fructooligosaccharides—Occurrence, preparation, and application." Enzyme and Microbial Technology 19, no. 2 (August 1996): 107–17. http://dx.doi.org/10.1016/0141-0229(95)00188-3.

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16

Patel, V., G. Saunders, and C. Bucke. "Production of fructooligosaccharides byFusarium oxysporum." Biotechnology Letters 16, no. 11 (November 1994): 1139–44. http://dx.doi.org/10.1007/bf01020840.

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17

Zhou, Lihong, Hui Ni, Linlin Zhang, Wenyong Wu, Tengqian Zhang, Qi Su, Jing Zhou, et al. "Calculating Relative Correction Factors for Quantitative Analysis with HILIC-HPLC-ELSD Method: Eight Fructooligosaccharides of Morinda Officinalis as a Case Study." Journal of Analytical Methods in Chemistry 2022 (August 12, 2022): 1–10. http://dx.doi.org/10.1155/2022/8022473.

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Objective. Because the response of evaporating light scattering detector (ELSD) being in a nonlinear mode, there is no consensus on the method of calculating its relative correction factors (RCF), which limits the application of the quantitative analysis for multi-components by a single marker (QAMS) with LC-ELSD. Methods. Using eight fructooligosaccharides of Morinda officinalis as a case study, the nystose (GF3) as a single standard was adopted to develop a QAMS method to simultaneously determine the other seven fructooligosaccharides with HILIC-HPLC-ELSD method. Six calculation methods of RCF were investigated to select the most reasonable method. The relative error of content between the QAMS and the external standard method (ESM) obtained from 30 batches of samples was used as an indicator to evaluate the six methods. Finally, a chemometrics analysis was performed to find the differential components among MO and its three processing products. Results. It was first reported that only one calculation method was scientific for calculating RCF for the LC-ELSD method. The RCFs of GF3 to the other seven fructooligosaccharides (GF1–GF8) were obtained as 0.86, 0.91, 0.93, 1.05, 1.15, 1.12, and 1.18, respectively. The QAMS of eight fructooligosaccharides of Morinda officinalis was validated with good linearity (R2 > 0.9998) and accepted the accuracy of 95–105% (RSD < 1.81%) based on nystose. Finally, Morinda officinalis and its three processed products were distinguished and could be differed based on the content of the eight fructooligosaccharides. Conclusion. The scientific calculation method of RCF would be of great significance for developing the QAMS method in Pharmacopoeia when performing the LC-ELSD method.
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18

KLEWICKI, R., and M. UCZCIWEK. "Effect of osmotic dehydration in fructose, sucrose and fructooligosaccharide solutions on the content of saccharides in plums and apples and their energy value." Agricultural and Food Science 17, no. 4 (December 4, 2008): 367. http://dx.doi.org/10.2137/145960608787235559.

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Plums (Najbolia and Stanley) and apples (Idared) were subjected to osmotic dehydration in 50% solutions of fructose, sucrose and fructooligosaccharides (FOS) at 22, 40 and 60 °C for 24 hours. The content of fructooligosaccharides, sucrose and monosaccharides in dried material was determined. Plums osmosed in fructose contained from 22.3% w/w to 29.6%w/w of this saccharide depending on the process temperature. The content of sucrose in plums and apples varied from 18.6% w/w to 30.4% w/w after using sucrose as osmotic agent. Material processed at 40 °C was characterised by the highest content of FOS: 22.6–24.7% w/w in plums (nystose as osmotic agent) and 13.7% w/w in apples (FOS preparation as osmotic agent). The partial replacement of sucrose and monosaccharides by fructooligosaccharides reduced the energy value of carbohydrates in dried material by 12–37% depending on the process conditions.;
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19

Mao, Shuhong, Yanna Liu, Juanjuan Yang, Xiaoyu Ma, Fang Zeng, Zhaohui Zhang, Shan Wang, Haichao Han, Hui-Min Qin, and Fuping Lu. "Cloning, expression and characterization of a novel fructosyltransferase from Aspergillus niger and its application in the synthesis of fructooligosaccharides." RSC Advances 9, no. 41 (2019): 23856–63. http://dx.doi.org/10.1039/c9ra02520k.

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20

Setiarto, Raden Haryo Bimo, Nunuk Widhyastuti, and Nimas Ayu Rikmawati. "Optimasi Konsentrasi Fruktooligosakarida untuk Meningkatkan Pertumbuhan Bakteri Asam Laktat Starter Yoghurt (CONCENTRATION OPTIMIZATION OF FRUCTOOLIGOSACCHARIDES TO INCREASE GROWTH OF LACTIC ACID BACTERIA YOGHURT STARTER)." Jurnal Veteriner 18, no. 3 (September 4, 2017): 428. http://dx.doi.org/10.19087/jveteriner.2017.18.3.428.

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Fructooligosaccharides are prebiotic source that widely used in food products, such as: fermented milk and infant formula. Prebiotics are food components that cannot be digested in the digestive tract enzymatically. However, they can be fermented by probiotic bacteria in the colon. This study aimed to determine the optimum concentrations of fructooligosaccharides in order to increase the growth of lactic acid bacteria yogurt starter (Lactobacillus acidophillus, Lactobacillus bulgaricus, Streptococcus thermophillus). Optimation concentration of fructooligosaccharides on the growth of Lactobacillus acidophilus, Lactobacillus bulgaricus, Streptococcus thermophillus can be determined based on OD (optical density), TPC (Total Plate Count), total lactic acid content and pH value. Suplementation of fructooligosaccharides 1 % (w/v) on the media MRSB increased significantly the growth of L. acidophilus, L.bulgaricus, S. thermophilus. Furthermore, L. acidophilus, L. bulgaricus and S. thermophilus experienced exponential growth phase during incubation period from 6 to 18 hours. Fermentation of L. acidophilus, L. bulgaricus, S. thermophilus in MRSB medium supplemented by fructooligosaccharides decreased the pH value of the formation of organic acids from 6.00 to 4.00. ABSTRAK Fruktooligosakarida adalah sumber prebiotik yang banyak digunakan dalam produk pangan olahan seperti susu fermentasi dan susu formula. Prebiotik adalah komponen bahan pangan fungsional yang tidak dapat dicerna di dalam saluran pencernaan secara enzimatik sehingga akan difermentasi oleh bakteri probiotik dalam usus besar. Penelitian ini bertujuan menentukan konsentrasi optimum fruktooligosakarida untuk meningkatkan pertumbuhan bakteri asam laktat starter yoghurt (Lactobacillus acidophillus, Lactobacillus bulgaricus, Streptococcus thermophillus). Konsentrasi optimum fruktooligosakarida pada pertumbuhan Lactobacillus acidophilus, Lactobacillus bulgaricus, Streptococcus thermophillus dapat ditentukan berdasarkan OD (optical density), TPC (Total Plate Count), total asam laktat tertitrasi dan nilai pH. Penambahan fruktooligosakarida 1% (b/v) pada media MRSB (Man, Rogosa Sharpe Broth) dapat meningkatkan secara signifikan pertumbuhan L. acidophilus, L. bulgaricus, S. thermophilus. Bakteri asam laktat L. acidophilus, L. bulgaricus dan S. thermophilus mengalami fase pertumbuhan eksponensial selama masa inkubasi 6-18 jam. Fermentasi L. acidophilus, L. bulgaricus, S. thermophilus pada MRSB dengan penambahan fruktooligosakarida dapat menurunkan nilai pH dari kisaran 6,00 hingga 4,00 karena pembentukan asam-asam organik.
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Flores-Maltos, Dulce A., Solange I. Mussatto, Juan C. Contreras-Esquivel, Raúl Rodríguez-Herrera, José A. Teixeira, and Cristóbal N. Aguilar. "Biotechnological production and application of fructooligosaccharides." Critical Reviews in Biotechnology 36, no. 2 (December 18, 2014): 259–67. http://dx.doi.org/10.3109/07388551.2014.953443.

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Pejin, Boris, Marko Sabovljevic, Vele Tesevic, and Vlatka Vajs. "Further Study on Fructooligosaccharides ofRhodobryum ontariense." Cryptogamie, Bryologie 33, no. 2 (April 2012): 191–96. http://dx.doi.org/10.7872/cryb.v33.iss2.2012.191.

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23

Roberfroid, Marcel B. "Chicory fructooligosaccharides and the gastrointestinal tract." Nutrition 16, no. 7-8 (July 2000): 677–79. http://dx.doi.org/10.1016/s0899-9007(00)00244-6.

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Tamiya, Taiga, Haruko Hirose, Keiko Kunihiro, Takushi Yamamoto, Kiyotsuna Toyohara, Yasunori Nakayama, and Eiichi Kitazono. "Mass spectrometry imaging of BARLEYmax fructooligosaccharides." Journal of Cereal Science 95 (September 2020): 103068. http://dx.doi.org/10.1016/j.jcs.2020.103068.

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Yan, Xiumei, Jingbin Yan, Qiangwei Xiang, Fanyan Wang, Huan Dai, Kaiyu Huang, Lingjuan Fang, Hao Yao, Lingya Wang, and Weixi Zhang. "Fructooligosaccharides protect against OVA-induced food allergy in mice by regulating the Th17/Treg cell balance using tryptophan metabolites." Food & Function 12, no. 7 (2021): 3191–205. http://dx.doi.org/10.1039/d0fo03371e.

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Mao, Bingyong, Dongyao Li, Jianxin Zhao, Xiaoming Liu, Zhennan Gu, Yong Q. Chen, Hao Zhang, and Wei Chen. "In vitro fermentation of fructooligosaccharides with human gut bacteria." Food & Function 6, no. 3 (2015): 947–54. http://dx.doi.org/10.1039/c4fo01082e.

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Krivorotova, Tatjana, and Jolanta Sereikaite. "Correlation between Fructan Exohydrolase Activity and the Quality of Helianthus tuberosus L. Tubers." Agronomy 8, no. 9 (September 13, 2018): 184. http://dx.doi.org/10.3390/agronomy8090184.

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Jerusalem artichoke tubers have diverse applications in the food industry as well as in biotechnology. Their suitability depends mostly on the inulin content. Seasonal fluctuations of fructan exohydrolase activity responsible for inulin degradation was investigated in the tubers of three Jerusalem artichoke cultivars. The changes of fructan exohydrolase activity positively correlated with the changes of the content of total and short fructooligosaccharides. Therefore, to extract inulin with higher degree of polymerization for biotechnological purposes, the tubers of Jerusalem artichoke should be uprooted in autumn before the level of fructan exohydrolase reaches its maximum. If short fructooligosaccharides are desirable, the tubers in late autumn or spring tubers overwintered in soil are suitable.
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Zivkovic, B., W. Migdal, and C. Radovic. "Prebiotics in nutrition of sows and piglets." Biotehnologija u stocarstvu 27, no. 3 (2011): 547–59. http://dx.doi.org/10.2298/bah1103547z.

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The effects of prebiotic Bio Mos (0.2%) used in nutrition of gestating and sows in lactation, as well as Bio Mos (0.5%) and fructooligosaccharides (0.4%) used in nutrition of suckling piglets were investigated. Obtained results showed that the introduction of additives in mixtures influenced: greater food intake of sows in lactation by 13.75 %, by 14.7% more born piglets and by 3.6% heavier piglets at birth, greater litter weight by 3.1 % at weaning and better intake of pre-starter by 6.7% per litter during lactation. In general, obtained results showed that the use of investigated prebiotic Bio Mos and fructooligosaccharides are recommended for use in nutrition of sows and suckling piglets.
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Charoenwongpaiboon, Thanapon, Karan Wangpaiboon, Rath Pichyangkura, and Manchumas Hengsakul Prousoontorn. "Highly porous core–shell chitosan beads with superb immobilization efficiency forLactobacillus reuteri121 inulosucrase and production of inulin-type fructooligosaccharides." RSC Advances 8, no. 30 (2018): 17008–16. http://dx.doi.org/10.1039/c8ra02241k.

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Liu, Lei, Daiwen Chen, Bing Yu, Heng Yin, Zhiqing Huang, Yuheng Luo, Ping Zheng, et al. "Fructooligosaccharides improve growth performance and intestinal epithelium function in weaned pigs exposed to enterotoxigenic Escherichia coli." Food & Function 11, no. 11 (2020): 9599–612. http://dx.doi.org/10.1039/d0fo01998d.

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Silva, C. A., C. P. Dias, M. A. Callegari, A. M. Bridi, R. K. S. Santos, F. G. Luiggi, V. L. Santos, and J. B. Silva. "Prebiotics and butyric acid can replace colistin as a growth promoter for nursery piglets." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 72, no. 4 (August 2020): 1449–57. http://dx.doi.org/10.1590/1678-4162-11596.

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ABSTRACT This study aimed to assess different prebiotic concentrations and principles, in addition to calcium butyrate, aiming to replace colistin as a growth promoter. The sample consisted of 120 piglets weaned at 22 days old with mean initial weight of 5.475 ± 0.719kg. The animals were assigned to random blocks in six treatments corresponding to the use of the following dietary additives: T1) colistin (40 ppm); T2) β-glucan/mannan-oligosaccharides (0.2%); T3) calcium butyrate (0.1%); T4) β-glucan/mannan-oligosaccharides (0.1%) + fructooligosaccharides (0.01%) + galactooligosaccharides (0.09%); T5) β-glucan/mannan-oligosaccharides (0.1%) + fructooligosaccharides (0.03%) + galactooligosaccharides (0.07%); and T6) β-glucan/mannan-oligosaccharides (0.1%) + fructooligosaccharides (0.05%) + galactooligosaccharides (0.05%). The results showed no difference among treatments for the performance parameters in any of the phases evaluated. For diarrhea incidence and intensity, the results indicated that the treatments with alternative additives had similar effects as the group treated with colistin. A significant difference was found for the profile of propionic acid (0.23% colistin and 0.32%, 0.36%, 0.37% additives) and total fatty acids (0.67% colistin and 0.97% additives) values in the caecum. The supplementation with different compositions and concentrations of prebiotics and butyric acid may viably replace colistin in controlling diarrhea and modulating volatile fatty acid production in the caecum.
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Aguiar-Oliveira, Elizama, Maria Isabel Rodrigues, and Francisco Maugeri. "Optimization of fructooligosaccharides synthesis by immobilized fructosyltransferase." Current Chemical Biology 6, no. 1 (March 1, 2012): 42–52. http://dx.doi.org/10.2174/187231312799984367.

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Aguiar-Oliveira, Elizama, Maria Isabel Rodrigues, and Francisco Maugeri. "Optimization of fructooligosaccharides synthesis by immobilized fructosyltransferase." Current Chemical Biology 6, no. 1 (March 1, 2012): 42–52. http://dx.doi.org/10.2174/2212796811206010042.

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Kuhn, Raquel Cristine, Laura Palacio, Pedro Prádanos, Antonio Hernández, and Francisco Maugeri Filho. "Selection of membranes for purification of fructooligosaccharides." Desalination and Water Treatment 27, no. 1-3 (March 2011): 18–24. http://dx.doi.org/10.5004/dwt.2011.2038.

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35

Delzenne, Nathalie M., Nadine Kok, Marie-France Fiordaliso, Dominique M. Deboyser, Fabienne M. Goethals, and Marcel B. Roberfroid. "Dietary fructooligosaccharides modify lipid metabolism in rats." American Journal of Clinical Nutrition 57, no. 5 (May 1, 1993): 820S. http://dx.doi.org/10.1093/ajcn/57.5.820s.

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Agopian, Roberta Ghedini Der, Claudinéia Aparecida Soares, Eduardo Purgatto, Beatriz Rosana Cordenunsi, and Franco Maria Lajolo. "Identification of Fructooligosaccharides in Different Banana Cultivars." Journal of Agricultural and Food Chemistry 56, no. 9 (May 2008): 3305–10. http://dx.doi.org/10.1021/jf073011l.

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37

Ganaie, Mohd Anis, Agbaje Lateef, and Uma Shanker Gupta. "Enzymatic Trends of Fructooligosaccharides Production by Microorganisms." Applied Biochemistry and Biotechnology 172, no. 4 (December 14, 2013): 2143–59. http://dx.doi.org/10.1007/s12010-013-0661-9.

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38

Sabater-Molina, M., E. Larqué, F. Torrella, and S. Zamora. "Dietary fructooligosaccharides and potential benefits on health." Journal of Physiology and Biochemistry 65, no. 3 (September 2009): 315–28. http://dx.doi.org/10.1007/bf03180584.

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39

Hidaka, Hidemasa, Masao Hirayama, and Kazuhiko Yamada. "Review Article: Fructooligosaccharides Enzymatic Preparation and Biofunctions." Journal of Carbohydrate Chemistry 10, no. 4 (January 1991): 509–22. http://dx.doi.org/10.1080/07328309108543928.

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40

LOGUE, ANN C. "Fructooligosaccharides Promising As ‘Prebiotic’ in Crohn's Therapy." Family Practice News 35, no. 14 (July 2005): 55. http://dx.doi.org/10.1016/s0300-7073(05)71067-7.

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41

Kaplan, Handan, and Robert W. Hutkins. "Metabolism of Fructooligosaccharides by Lactobacillus paracasei 1195." Applied and Environmental Microbiology 69, no. 4 (April 2003): 2217–22. http://dx.doi.org/10.1128/aem.69.4.2217-2222.2003.

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ABSTRACT Fermentation of fructooligosaccharides (FOS) and other oligosaccharides has been suggested to be an important property for the selection of bacterial strains used as probiotics. However, little information is available on FOS transport and metabolism by lactic acid bacteria and other probiotic bacteria. The objectives of this research were to identify and characterize the FOS transport system of Lactobacillus paracasei 1195. Radiolabeled FOS was synthesized enzymatically from [3H]sucrose and purified by column and thin-layer chromatography, yielding three main products: glucose (G) α-1,2 linked to two, three, or four fructose (F) units (GF2, GF3, and GF4, respectively). FOS hydrolysis activity was detected only in cell extracts prepared from FOS- or sucrose-grown cells and was absent in cell supernatants, indicating that transport must precede hydrolysis. FOS transport assays revealed that the uptake of GF2 and GF3 was rapid, whereas little GF4 uptake occurred. Competition experiments showed that glucose, fructose, and sucrose reduced FOS uptake but that other mono-, di-, and trisaccharides were less inhibitory. When cells were treated with sodium fluoride, iodoacetic acid, or other metabolic inhibitors, FOS transport rates were reduced by up to 60%; however, ionophores that abolished the proton motive force only slightly decreased FOS transport. In contrast, uptake was inhibited by ortho-vanadate, an inhibitor of ATP-binding cassette transport systems. De-energized cells had low intracellular ATP concentrations and had a reduced capacity to accumulate FOS. These results suggest that FOS transport in L. paracasei 1195 is mediated by an ATP-dependent transport system having specificity for a narrow range of substrates.
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42

Ten Bruggencate, Sandra J. M., Ingeborg M. J. Bovee-Oudenhoven, Mischa L. G. Lettink-Wissink, and Roelof Van der Meer. "Dietary Fructooligosaccharides Increase Intestinal Permeability in Rats." Journal of Nutrition 135, no. 4 (April 1, 2005): 837–42. http://dx.doi.org/10.1093/jn/135.4.837.

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43

Barbosa, A. F., R. S. Henrique, A. S. Lucho, V. Paffaro, and J. M. Schneedorf. "Action of Chicory Fructooligosaccharides on Biomimetic Membranes." International Journal of Electrochemistry 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/186109.

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Fructooligosaccharides from chicory (FOSC) are functional prebiotic foods recognized to exert several well-being effects in human health and animal production, as decreasing blood lipids, modulating the gut immune system, enhancing mineral bioavailability, and inhibiting microbial growth, among others. Mechanisms of actions directly on cell metabolism and structure are however little known. In this sense this work was targeted to investigate the interaction of FOSC with biomimetic membranes (liposomes and supported bilayer membrane; s-BLM) through cyclic voltammetry, impedance spectroscopy, spectrofluorimetry, and microscopy. FOSC was able to disrupt the membrane structure of liposomes and s-BLM from the onset of molecular pores induced on it. The mechanism of interaction of fructans with biomimetic membranes suggests hydrogen bonding between the polyhydroxylated structure of the oligosaccharides and the negative polar group of L-α-phosphatidylcholine (PC) present in both liposomes and s-BLM.
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Chen, Maoshen, Xiaolei Yong, John Nsor-Atindana, Kingsley George Masamba, Jianguo Ma, and Fang Zhong. "Quantitative optimization and assessments of supplemented fructooligosaccharides in dry dog food." RSC Advances 6, no. 111 (2016): 110047–52. http://dx.doi.org/10.1039/c6ra19721c.

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The effects of supplementation of fructooligosaccharides (FOS) in dry dog food on the populations of microflora, short-chain fatty acid (SCFA) production, fecal protein catabolites and fecal quality in puppies were investigated.
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45

Charoenwongpaiboon, Thanapon, Karan Wangpaiboon, Rath Pichyangkura, and Manchumas Hengsakul Prousoontorn. "Correction: Highly porous core–shell chitosan beads with superb immobilization efficiency for Lactobacillus reuteri 121 inulosucrase and production of inulin-type fructooligosaccharides." RSC Advances 9, no. 8 (2019): 4453. http://dx.doi.org/10.1039/c9ra90009h.

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Correction for ‘Highly porous core–shell chitosan beads with superb immobilization efficiency for Lactobacillus reuteri 121 inulosucrase and production of inulin-type fructooligosaccharides’ by Thanapon Charoenwongpaiboon et al., RSC Adv., 2018, 8, 17008–17016.
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Charoenwongpaiboon, Thanapon, Rath Pichyangkura, Robert A. Field, and Manchumas Hengsakul Prousoontorn. "Preparation of Cross-Linked Enzyme Aggregates (CLEAs) of an Inulosucrase Mutant for the Enzymatic Synthesis of Inulin-Type Fructooligosaccharides." Catalysts 9, no. 8 (July 27, 2019): 641. http://dx.doi.org/10.3390/catal9080641.

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Fructooligosaccharides are well-known carbohydrate molecules that exhibit good probiotic activity and are widely used as sweeteners. Inulin-type fructooligosaccharides (IFOs) can be synthesized from sucrose using inulosucrase. In this study, cross-linked enzyme aggregates (CLEAs) of Lactobacillus reuteri 121 inulosucrase (R483A-LrInu) were prepared and used as a biocatalyst for IFOs production. Under optimum conditions, R483A-LrInu CLEAs retained 42% of original inulosucrase activity. Biochemical characterization demonstrated that the optimum pH of inulosucrase changed from 5 to 4 after immobilization, while the optimum temperature was unchanged. Furthermore, the pH stability and thermostability of the R483A-LrInu CLEAs was significantly improved. IFOs product characterization indicated that the product specificity of the enzyme was impacted by CLEA generation, producing a narrower range of IFOs than the soluble enzyme. In addition, the R483A-LrInu CLEAs showed operational stability in the batch synthesis of IFOs.
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Borromei, Chiara, Maria Careri, Antonella Cavazza, Claudio Corradini, Lisa Elviri, Alessandro Mangia, and Cristiana Merusi. "Evaluation of Fructooligosaccharides and Inulins as Potentially Health Benefiting Food Ingredients by HPAEC-PED and MALDI-TOF MS." International Journal of Analytical Chemistry 2009 (2009): 1–9. http://dx.doi.org/10.1155/2009/530639.

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This paper describes the complementarity of high-performance anion exchange chromatography coupled with pulsed electrochemical detection (HPAEC-PED) and matrix-assisted laser desorption/ionization mass spectrometry (MALDI-TOF-MS) to evaluate commercial available fructans (fructooligosaccharides (FOS) and inulins), having different degrees of polymerization (DP) which are usually employed by food industry as functional ingredients either for their prebiotic properties or as a fat replacer, giving a fat-like mouth feel and texture. The developed HPAEC-PED methods are able to analyze FOS (fructans with DP 3–10) and inulins (DP ranging from 3 to 80) with a good resolution and relatively short retention times to evaluate structural differences between fructooligosaccharide and inulins and the possible presence of inulooligosaccharides as well as of branching. To characterize FOS and inulin at different degrees of polymerization and to assure correct molecular assignment, MALDI-TOF MS analysis was also investigated. The 2,5-dihydroxy benzoic acid (2,5-DHB) was found to be the best matrix for FOS analysis as Actilight and Raftilose P95 products, while 3-aminoquinoline (3-AQ) seems to be the best matrix for inulin with higher DP. The applicability of the optimized methods to the identification and determination of FOS contained in a symbiotic milk as well as a type of inulin added as functional ingredient to a cooked ham is demonstrated.
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Singh, R. S., Taranjeet Singh, Dhandeep Singh, and John F. Kennedy. "HPTLC-densitometry quantification of fructooligosaccharides from inulin hydrolysate." International Journal of Biological Macromolecules 177 (April 2021): 221–28. http://dx.doi.org/10.1016/j.ijbiomac.2021.02.116.

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49

Xu, Chuanlai, Xudong Chen, Cheng Ji, Qiugang Ma, and Kai Hao. "Study of the Application of Fructooligosaccharides in Piglets." Asian-Australasian Journal of Animal Sciences 18, no. 7 (November 26, 2005): 1011–16. http://dx.doi.org/10.5713/ajas.2005.1011.

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50

Reiffová, Katarína, Jana Podolonovičová, Andrej Oriňák, Karol Flórián, and Tat’ána Gondová. "Preliminary TLC analysis of fructooligosaccharides as feed additives." Journal of Planar Chromatography – Modern TLC 16, no. 1 (February 2003): 52–57. http://dx.doi.org/10.1556/jpc.16.2003.1.11.

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