Academic literature on the topic 'FTO rs9939609'

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Journal articles on the topic "FTO rs9939609"

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Wang, Li, QiZhong Yi, Hua Yao, et al. "Correlations between FTO Gene Polymorphisms and TSH Level in Uyghur Chinese Patients with Type 2 Diabetes." BioMed Research International 2021 (June 26, 2021): 1–7. http://dx.doi.org/10.1155/2021/6646750.

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Objective. The aim of this study was to investigate the correlation between polymorphisms in the FTO gene and TSH level in Uyghur patients with type 2 diabetes in the Xinjiang region. Material and Methods. This cohort was made up of 498 Uyghur patients with type 2 diabetes who underwent genotype screening for rs8050136 and rs9939609 using the Sequenom MassARRAY system. The distribution frequencies of the genotypes and alleles at rs8050136 and rs993960 were compared between two patient groups, those with TSH < 2.5 mU/L and those with TSH ≥ 2.5 mU/L group. We further evaluated the relationshi
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Nurmaliana, Tati, and Vector Stephen Dewangga. "Polimorfisme Gen FTO Rs9939609 Terhadap Konsentrasi Trigliserida Pada Subyek Obesitas Sentral." Jurnal Analis Kesehatan 12, no. 2 (2023): 65–70. http://dx.doi.org/10.26630/jak.v12i2.3908.

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Obesitas sentral merupakan keadaan bagian perut bagian tengah terdapat lemak yang berlebih. Penumpukan lemak berlebihan mengakibatkan peningkatan jumlah asam lemak bebas yang dihidrolisis LPL endotel. Free Fatty Acid (FFA) dilepaskan karena adanya penimbunan lemak yang berlebihan juga menghambat lipogenesis sehingga menghambat klirens serum triasilgliserol dan terjadinya hipertrigliseridemia. Gen FTO (fat mass and obesity associated) rs9939609 banyak dikaitkan dengan massa lemak dan obesitas. Tujuan penelitian untuk mengetahui gambaran polimorfisme gen FTO rs9939609 dan faktor risiko polimorfi
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HIZ ÇİÇEKLİYURT, Meliha Merve, Sevilay OĞUZ KILIÇ, and Levent ELMAS. "EFFECT OF FTO rs9939609 POLIMORPHISM ON OBESITY IN TURKISH POPULATION." Journal of Scientific Perspectives 4, no. 4 (2020): 255–62. http://dx.doi.org/10.26900/jsp.4.022.

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Obesity is a disease that is affected by environmental conditions as well as genetic predisposition. This is a case-control study that aimed to investigate the relationship between FTO rs9939609 polymorphism and obesity. The relation between the rs9939609 polymorphism and obesity in 80 ower-weight (BMI≥30) and 131 under/normal weight (BMI<30) subjects was examined. The allele and genotype frequencies of each group were determined by the allele counting method. The relationship between single nucleotide exchange and obesity risk was calculated using the odds ratio. Statistical analyzes were
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Yusof, Hartini, Nur Aimi Mohd Rodzi, Nurhanis Syahira Shakir, Azrina Begam Mohd Ali, Zana Jamal Kareem, and Fazleen Haslinda Mohd Hatta. "DEVELOPMENT OF PCR-BASED GENOTYPING METHOD FOR FAT MASS OBESITY-ASSOCIATED (FTO) GENE POLYMORPHISM RS9939609." Journal of Health and Translational Medicine sp2023, no. 1 (2023): 51–54. http://dx.doi.org/10.22452/jummec.sp2023no2.5.

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Malaysia has the highest obesity rate in Southeast Asia and is growing. Environmental and genetic factors influence weight increase and obesity, leading to numerous diseases and mortality. This study aimed to develop a genotyping method to detect FTO gene variant rs9939609, known for its association with body mass index (BMI) and obesity. In-house primers detected rs9939609. Two common primers flanked the variation region, and two more primers identified the wild type and alternative allele. Capillary sequencing verified results. We developed FTO gene variant rs9939609 genotyping. This method
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Abd Ali, A. H., O. V. Bocharova, T. P. Shkurat, M. A. Shkurat, and M. A. Amelina. "Association of Ser447Ter polymorphisms of the LPL gene and rs9939609 of the FTO gene with obesity in children and adolescents in the Rostov-on-Don population." Вестник Пермского университета. Серия «Биология»=Bulletin of Perm University. Biology, no. 2 (2021): 119–27. http://dx.doi.org/10.17072/1994-9952-2021-2-119-127.

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The aim of this study was to study the correlation between the Ser447ter (C-G) polymorphisms of the LPL gene and rs9939609 of the FTO gene and obesity in children and adolescents of the Rostov region (Russia). A case-control study examined the relationship between the rs9939609 polymorphisms of the FTO gene and Ser447Ter (S447X) of the LPL gene with obesity in 520 children and adolescents of both sexes aged 3 to 18 years: the main group consisted of 370 obese children and adolescents, and the control group - 150 children and adolescents without obesity. Genotyping of polymorphisms T / A rs9939
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Priliani, Lidwina, Sukma Oktavianthi, Ria Hasnita, et al. "Obesity in the Balinese is associated with FTO rs9939609 and rs1421085 single nucleotide polymorphisms." PeerJ 8 (January 3, 2020): e8327. http://dx.doi.org/10.7717/peerj.8327.

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Obesity prevalence is increasing worldwide, including in the Bali Province, Indonesia, a popular tourism destination area. The common single nucleotide polymorphisms (SNPs) rs9939609 and rs1421085 of the fat mass and obesity-associated (FTO) gene have been repeatedly reported as one of the important obesity genetic risk factors. We have examined the associations of FTO rs9939609 and rs1421085 SNPs with obesity in the 612 unrelated Balinese subjects living in urban and rural areas. Linear and logistic regression analyses with adjustment for age and gender were employed to investigate the associ
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NING, MEIWEI, AOHONG XU, RONG ZENG, JINRUO XUE, BODA WANG, and XIANG LIU. "The effect of overweight/obesity and FTO gene polymorphism on liver function-related parameters in Chinese adolescents." National Medical Journal of India 37 (February 7, 2025): 248–52. https://doi.org/10.25259/nmji_264_2022.

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Background Overweight/obesity is an important risk factor for liver disease, affecting changes in liver function-related parameters. The fat mass and obesity associated (FTO) gene has been reported to have a link between overweight/obesity and liver fat metabolism. We studied the association of FTO rs9939609 variants with liver function-related parameters and overweight/obesity in Chinese adolescents aged 16 to 26 as freshmen. Methods We examined rs9939609 polymorphisms in 198 control and 173 overweight/obese people, and the genotypes of the samples were analyzed by Sanger sequencing. We inves
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А.А., Яковлева,, Торгунакова, А.В., Соболева, О.А., and Минина, В.И. "FTO (rs9939609), FABP2 (rs1799883), and PPARG (rs1801282) gene polymorphisms and obesity risk in men living in Kuzbass." Nauchno-prakticheskii zhurnal «Medicinskaia genetika, no. 9 (September 30, 2022): 13–16. http://dx.doi.org/10.25557/2073-7998.2022.09.13-16.

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Цель: изучение ассоциаций полиморфизма генов FTO, FABP2, PPARG и ожирения у жителей Кузбасса. Методы. Выборка для исследования составила 395 мужчин, жителей Кузбасса. Средний возраст испытуемых составил 59±7,7 года. Согласно анкетным данным, все обследованные мужчины отнесли себя к русской национальности. Частота ожирения в данной выборке (индекс массы тела>30) составила 46,3%. Генотипирование полиморфных вариантов FTO (rs9939609), FABP2 (rs1799883) и PPARG (rs1801282) проводилось с использованием TaqMan PCR. Далее проводилась проверка ассоциации данных полиморфных вариантов с ожирением в р
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Sun, Yanlei, Jiazhong Sun, Xiang Wang, Wei You, and Mei Yang. "Variants in the fat mass and obesity associated (FTO) gene are associated with obesity and C-reactive protein levels in Chinese Han populations." Clinical & Investigative Medicine 33, no. 6 (2010): 405. http://dx.doi.org/10.25011/cim.v33i6.14592.

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Purpose: Various genetic variants of the fat mass and obesity associated gene (FTO) have been linked to obesity in populations of Europeans. Low-grade inflammation is a key feature of obesity, characterized by elevated plasma levels of C-reactive protein (CRP). In the present study, we have investigated whether the FTO-risk variant is associated with obesity and CRP in the Chinese population. Methods: 1799 individuals aged 50-70 years (896 men and 903 women), including both obese (560 cases) and control individuals, (1200 cases) were recruited. The FTO rs9939609 polymorphism was tested using s
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Tabassum, Sobia, Sadaf Mushtaq, M. Naveed Anwar, et al. "Genetic Association of FTO rs9939609 Polymorphism with Hypertension in Pakistani Population." Pakistan Journal of Medical and Health Sciences 15, no. 11 (2021): 2985–88. http://dx.doi.org/10.53350/pjmhs2115112985.

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Background: Hypertension is a medical condition that often occurs parallel to diabetes and obesity. Previously, the role of fat mass and obesity associated (FTO) gene rs9939609 polymorphism (c.46-23525T>A) with obesity has been reported while prevalence and etiological differences exist among different regions and ethnic groups. Aim: To investigate the association of FTO rs9939609 SNP with hypertension in Pakistani population. Study design: Cross-sectional study. Place and duration of study: Institute of Biomedical and Genetic Engineering (IBGE), Islamabad, Pakistan from 1st January 2019 to
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Dissertations / Theses on the topic "FTO rs9939609"

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Martínez, Martínez María de los Ángeles 474387, and Martínez María de los Ángeles Martínez. "Presencia del polimorfismo FTO rs9939609 en mujeres embarazadas con riesgo de desarrollo de diabetes gestacional." Tesis de doctorado, Universidad Autónoma del Estado de México, 2020. http://hdl.handle.net/20.500.11799/109123.

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En los últimos años a nivel mundial la salud pública y lo relacionado a enfermedades metabólicas como diabetes mellitus, obesidad, dislipidemias, entre otras; se ha convertido en todo un reto. Para México la diabetes representa la principal causa de morbimortalidad; así mismo, la diabetes gestacional se considera un factor de riesgo en el aumento de mortalidad materno infantil mundial, por lo que se buscan acciones de prevención pues representa un factor de riesgo para el desarrollo futuro de diabetes tipo 2. En particular la población mexicana es considerada por los organismos internacionales
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Castro, Mariana Laitano Dias de. "Associação do polimorfismo rs9939609 do FTO ao transtorno de compulsão alimentar periódica (TCAP) em pacientes obesos mórbidos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2013. http://hdl.handle.net/10183/87112.

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Introdução: Obesidade é um dos principais problemas de saúde do século XXI, sendo ela um dos maiores preditores no desenvolvimento de doenças como diabetes melitos tipo 2, doenças cardiovasculares e alguns tipos de câncer. “Fat mass and obesity associated” (FTO) tem mostrado variações fortemente associadas com a obesidade e diabetes e obesidade. Entre as pessoas com obesidade grave, existe uma subpopulação que apresenta um tipo de transtorno alimentar conhecido como Transtorno da Compulsão Alimentar Periódica. Devido à sua expressão no hipotálamo, o FTO poderia estar associado com a modulação
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Bitello, Adriana Regina. "Relação entre a dieta e o polimorfismo rs9939609 do gene FTO e a interação entre os marcadores bioquímicos e nutricionais." reponame:Repositório Institucional da UNIVATES, 2014. http://hdl.handle.net/10737/484.

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Submitted by FERNANDA DA SILVA VON PORSTER (fdsvporster@univates.br) on 2014-06-02T17:12:47Z No. of bitstreams: 3 license_text: 21393 bytes, checksum: 7c4ecb3427d83129a338fc10c55e726a (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) 2014AdrianaReginaBitello.pdf: 740341 bytes, checksum: 3038e78bbc36511e66c5eab91ca5e5f3 (MD5)<br>Approved for entry into archive by Ana Paula Lisboa Monteiro (monteiro@univates.br) on 2014-06-05T12:30:58Z (GMT) No. of bitstreams: 3 license_text: 21393 bytes, checksum: 7c4ecb3427d83129a338fc10c55e726a (MD5) license_rdf: 23148 bytes, ch
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Horvath, Jaqueline Driemeyer Correia. "Genética da obesidade : polimorfismos do LEPR (rs1137101 e rs8179183), FTO (rs9939609) e suas associações com transtorno alimentar e parâmetros nutricionais em pacientes obesos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/164918.

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Steemburgo, Thais. "Interação gene e nutriente em pacientes com diabete melito tipo 2 : aspectos relacionados às complicações crônicas do diabetes, síndrome metabólica e efeitos dos polimorfismos rs9939609 (A/T) e rs7204609 (CT) do gene do FTO." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2009. http://hdl.handle.net/10183/16853.

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Book chapters on the topic "FTO rs9939609"

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"Fat mass profile in early adolescence: Influence of nutritional parameters and rs9939609 FTO polymorphism." In Advances in Biomolecular Medicine, edited by S. N. Fatimah, A. Purba, K. Roesmil, G. I. Nugraha, and A. M. Maskoen. CRC Press, 2017. http://dx.doi.org/10.1201/9781315208619-6.

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Conference papers on the topic "FTO rs9939609"

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Yakovleva, A. A., O. A. Soboleva, A. V. Torgunakova, and A. V. Ponasenko. "CONTRIBUTION OF INHERITED VARIANTS OF THE FTO (RS9939609) AND ADRB3 (RS4994) GENES TO THE RISK OF OBESITY DEVELOPMENT AMONG KUZBASS RESIDENTS." In I International Congress “The Latest Achievements of Medicine, Healthcare, and Health-Saving Technologies”. Kemerovo State University, 2023. http://dx.doi.org/10.21603/-i-ic-156.

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Objective: To study and compare the associations of FTO (rs9939609), ADRB3 (rs4994)&#x0D; gene polymorphisms with obesity in sick and healthy Kuzbass residents.&#x0D; The data of 1149 people (568 control and 581 main group) were used in this work. After&#x0D; statistical processing of the data, it was found that rs9939609 of FTO gene increases the risk of&#x0D; obesity in both healthy and atherosclerosis patients. No statistically significant associations were&#x0D; found in the ADRB3 gene.
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Валеева, Ф. В., Т. А. Киселева, К. Б. Хасанова, Д. Р. Исламов та Л. А. Сыдыкова. "СРАВНИТЕЛЬНЫЙ АНАЛИЗ АССОЦИАЦИИ ПОЛИМОРФИЗМА RS9939609 ГЕНА FTO У ПАЦИЕНТОВ С САХАРНЫМ ДИАБЕТОМ 2 ТИПА В ТАТАРСКОЙ И ЯКУТСКОЙ ПОПУЛЯЦИЯХ". У Сборник тезисов III Конференции по лечению и диагностике сахарного диабета «Фундаментальная и клиническая диабетология в 21 веке: от теории к практике». ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/diaconfiii25-26.05.23-22.

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ЦЕЛЬ: анализ распределения частот аллелей и генотипов полиморфизма rs9939609 гена FTO, ассоцииро-&#x0D; ванного с риском развития сахарного диабета 2 типа (СД2), у пациентов с СД 2 типа в якутской популяции&#x0D; и у жителей Республики Татарстан (РТ)&#x0D; МАТЕРИАЛЫ И МЕТОДЫ: в исследовании приняли участие пациенты с подтверждённым диагнозом&#x0D; СД 2 типа из популяции якутской национальности Республики Саха (Якутия), г. Якутск (n=132) и популяции&#x0D; РТ (n=134).&#x0D; ДНК выделяли из лейкоцитов крови сорбентным методом с помощью набора реагентов&#x0D; «АмплиПрайм ДНК-сорб-В» (ИнтерЛабСер
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Abd Ali, Alaa Hashim, Tatyana Pavlovna Shkurat, and Maria Aleksandrovna Amelina. "Investigation of the rs9939609 polymorphism of the FTO gene in obese children and adolescents living." In THE 9TH INTERNATIONAL CONFERENCE ON APPLIED SCIENCE AND TECHNOLOGY (ICAST 2021). AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0113704.

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Salgado-Montilla, Jeannette, Jorge Rodríguez-Caban, Lorena Gonzalez-Sepulveda, Ricardo Sanchez-Ortiz, and Margarita Irizarry-Ramirez. "Abstract 4836: Presence of FTO rs9939609 and rs9930506 and severity of prostate cancer in Puerto Ricans." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-4836.

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"Association between Fat Mass and Obesity Associated (FTO) Gene Polymorphism (rs9939609) and Polycystic Ovary Syndrome (PCOS): A Sri Lankan Study." In CABES-2017, DMCCIA-2017, FEBM-17, BDCMTE-17, LLHIS-17 and BMLE-17. Dignified Researchers Publication (DiRPUB), 2018. http://dx.doi.org/10.15242/dirpub.dir1217205.

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Hằng, Nguyễn Thị Thanh, Phạm Bùi Quang Minh, Trương Ngọc Mai, Nguyễn Thị Trung Thu, Nguyễn Thị Hồng Hạnh та Lê Thị Tuyết. "ẢNH HƯỞNG ĐA HÌNH NUCLEOTIDE ĐƠN RS9939609 GENE FTO ĐẾN BÉO PHÌ Ở TRẺ 24-60 THÁNG TUỔI TẠI HÀ NỘI". У HỘI NGHỊ KHOA HỌC QUỐC GIA LẦN THỨ 6 THÀNH PHỐ HUẾ. Nhà xuất bản Khoa học tự nhiên và Công nghệ, 2024. http://dx.doi.org/10.15625/vap.2024.0089.

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Ferreira, AS, AVAP Mendes, MLG Sodré, et al. "POLIMORFISMO DO GENE FAT MASS AND OBESITY-ASSOCIATED (FTO) E SUA ASSOCIAÇÃO COM LÍPIDES SÉRICO EM ADOLESCENTES." In Resumos do 55º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s2.8772.

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Objetivo: O gene Fat Mass and Obesity-Associated (FTO) desempenha um importante papel no metabolismo energético e na adipogênese. Ele tem sido associado ao maior ganho de massa de gordura corporal e dislipidemias, principalmente o alelo A. O objetivo deste estudo foi avaliar os níveis séricos de colesterol total e triglicerídeos em adolescentes e sua associação com o gene FTO variante rs9939609 (T&gt;A). Método: Trata-se de um estudo transversal com 144 adolescentes, com faixa etária entre 10 e 18 anos, analisados no período de 2016-2018, em uma capital do Nordeste brasileiro. As variáveis ana
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