Relevant bibliographies by topics / FTSAQ

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Academic literature on the topic 'FTSAQ'

Author: Grafiati
Published: 5 June 2025
Last updated: 15 July 2025

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Journal articles on the topic "FTSAQ"

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Goehring, Nathan W., Ivana Petrovska, Dana Boyd, and Jon Beckwith. "Mutants, Suppressors, and Wrinkled Colonies: Mutant Alleles of the Cell Division Gene ftsQ Point to Functional Domains in FtsQ and a Role for Domain 1C of FtsA in Divisome Assembly." Journal of Bacteriology 189, no. 2 (2006): 633–45. http://dx.doi.org/10.1128/jb.00991-06.

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ABSTRACT Cell division in Escherichia coli requires the concerted action of at least 10 essential proteins. One of these proteins, FtsQ, is physically associated with multiple essential division proteins, including FtsK, FtsL, FtsB, FtsW, and FtsI. In this work we performed a genetic analysis of the ftsQ gene. Our studies identified C-terminal residues essential for FtsQ's interaction with two downstream proteins, FtsL and FtsB. Here we also describe a novel screen for cell division mutants based on a wrinkled-colony morphology, which yielded several new point mutations in ftsQ. Two of these m
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Hale, Cynthia A., and Piet A. J. de Boer. "ZipA Is Required for Recruitment of FtsK, FtsQ, FtsL, and FtsN to the Septal Ring in Escherichia coli." Journal of Bacteriology 184, no. 9 (2002): 2552–56. http://dx.doi.org/10.1128/jb.184.9.2552-2556.2002.

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ABSTRACT The septal ring in Escherichia coli consists of at least nine essential gene products whose order of assembly resembles a mostly linear dependency pathway: FtsA and ZipA directly bind FtsZ polymers at the prospective division site, followed by the sequential addition of FtsK, FtsQ, FtsL, FtsW, FtsI, and FtsN. Recruitment of FtsK and all downstream components requires the prior localization of FtsA. Here we show that recruitment of FtsK, FtsQ, FtsL, and FtsN equally requires ZipA. The results imply that association of both FtsA and ZipA with FtsZ polymers is needed for further maturati
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Chen, Joseph C., David S. Weiss, Jean-Marc Ghigo, and Jon Beckwith. "Septal Localization of FtsQ, an Essential Cell Division Protein in Escherichia coli." Journal of Bacteriology 181, no. 2 (1999): 521–30. http://dx.doi.org/10.1128/jb.181.2.521-530.1999.

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ABSTRACT Septation in Escherichia coli requires several gene products. One of these, FtsQ, is a simple bitopic membrane protein with a short cytoplasmic N terminus, a membrane-spanning segment, and a periplasmic domain. We have constructed a merodiploid strain that expresses both FtsQ and the fusion protein green fluorescent protein (GFP)-FtsQ from single-copy chromosomal genes. The gfp-ftsQgene complements a null mutation in ftsQ. Fluorescence microscopy revealed that GFP-FtsQ localizes to the division site. Replacing the cytoplasmic and transmembrane domains of FtsQ with alternative membrane
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Eberhardt, Christian, Lars Kuerschner та David S. Weiss. "Probing the Catalytic Activity of a Cell Division-Specific Transpeptidase In Vivo with β-Lactams". Journal of Bacteriology 185, № 13 (2003): 3726–34. http://dx.doi.org/10.1128/jb.185.13.3726-3734.2003.

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ABSTRACT Penicillin-binding protein 3 (PBP3; also called FtsI) is a transpeptidase that catalyzes cross-linking of the peptidoglycan cell wall in the division septum of Escherichia coli. To determine whether the catalytic activity of PBP3 is activated during division, we assayed acylation of PBP3 with three β-lactams (cephalexin, aztreonam, and piperacillin) in growing cells. Acylation of PBP3 with cephalexin, but not aztreonam or piperacillin, appeared to be stimulated by cell division. Specifically, cephalexin acylated PBP3 about 50% faster in a population of dividing cells than in a populat
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Park, Kyung-Tae, Sebastien Pichoff, Shishen Du, and Joe Lutkenhaus. "FtsA acts through FtsW to promote cell wall synthesis during cell division in Escherichia coli." Proceedings of the National Academy of Sciences 118, no. 35 (2021): e2107210118. http://dx.doi.org/10.1073/pnas.2107210118.

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In Escherichia coli, FtsQLB is required to recruit the essential septal peptidoglycan (sPG) synthase FtsWI to FtsA, which tethers FtsZ filaments to the membrane. The arrival of FtsN switches FtsQLB in the periplasm and FtsA in the cytoplasm from a recruitment role to active forms that synergize to activate FtsWI. Genetic evidence indicates that the active form of FtsQLB has an altered conformation with an exposed domain of FtsL that acts on FtsI to activate FtsW. However, how FtsA contributes to the activation of FtsW is not clear, as it could promote the conformational change in FtsQLB or act
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NURZHAN, SHILMURZAYEV, TURSYNBAYEV ABYLAY, CHANDAN PAL SINGH, AN IGOR, and OMIRKUL BAISEYIT. "DEVELOPMENT OF ANALYSIS AND EVALUATION SKILLS IN A PHYSICS TEACHING THROUGH PRACTICAL WORK." International Journal Of Multidisciplinary Research And Studies 05, no. 06 (2022): 01–15. http://dx.doi.org/10.33826/ijmras/v05i06.3.

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This research paper addresses how to enhance analysis and evaluation skills in physics lessons using practical or lab work. Analysis and evaluation skills are very important for high school science students that can lead to developing critical thinking also, especially where English is a third-level language. Practicality plays a very important role in understanding complex and confusing topics, so integrating physics lessons with teaching practical work can improve a significant level of understanding. We have researched and analyzed data after applying for practical work in regular lessons a
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Dr., SHILMURZAYEV NURZHAN, TURSYNBAYEV ABYLAY Dr., CHANDAN PAL SINGH Dr., AN IGOR Dr., and OMIRKUL BAISEYIT5 Dr. "DEVELOPMENT OF ANALYSIS AND EVALUATION SKILLS IN A PHYSICS TEACHING THROUGH PRACTICAL WORK." International Journal Of Multidisciplinary Research And Studies 05, no. 06 (2022): 19–33. https://doi.org/10.33826/ijmras/v05i06.3.

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This research paper addresses how to enhance analysis and evaluation skills in physics lessons using practical or lab work. Analysis and evaluation skills are very important for high school science students that can lead to developing critical thinking also, especially where English is a third-level language. Practicality plays a very important role in understanding complex and confusing topics, so integrating physics lessons with teaching practical work can improve a significant level of understanding. We have researched and analyzed data after applying for practical work in regular lessons a
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Vinella, Daniel, Michael Cashel, and Richard D’Ari. "Selected Amplification of the Cell Division Genes ftsQ-ftsA-ftsZ in Escherichia coli." Genetics 156, no. 4 (2000): 1483–92. http://dx.doi.org/10.1093/genetics/156.4.1483.

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Abstract Rapidly growing Escherichia coli is unable to divide in the presence of the antibiotic mecillinam, whose direct target is penicillin-binding protein 2 (PBP2), responsible for the elongation of the cylindrical portion of the cell wall. Division can be restored in the absence of PBP2 activity by increasing the concentration of the cell division proteins FtsQ, FtsA, and FtsZ. We tried to identify regulators of the ftsQ-ftsA-ftsZ operon among mecillinam-resistant mutants, which include strains overexpressing these genes. By insertional mutagenesis with mini-Tn10 elements, we selected for
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Marbouty, Martial, Khalil Mazouni, Cyril Saguez, Corinne Cassier-Chauvat, and Franck Chauvat. "Characterization of the Synechocystis Strain PCC 6803 Penicillin-Binding Proteins and Cytokinetic Proteins FtsQ and FtsW and Their Network of Interactions with ZipN." Journal of Bacteriology 191, no. 16 (2009): 5123–33. http://dx.doi.org/10.1128/jb.00620-09.

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ABSTRACT Because very little is known about cell division in noncylindrical bacteria and cyanobacteria, we investigated 10 putative cytokinetic proteins in the unicellular spherical cyanobacterium Synechocystis strain PCC 6803. Concerning the eight penicillin-binding proteins (PBPs), which define three classes, we found that Synechocystis can survive in the absence of one but not two PBPs of either class A or class C, whereas the unique class B PBP (also termed FtsI) is indispensable. Furthermore, we showed that all three classes of PBPs are required for normal cell size. Similarly, the putati
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Reddy, Manjula. "Role of FtsEX in Cell Division of Escherichia coli: Viability of ftsEX Mutants Is Dependent on Functional SufI or High Osmotic Strength." Journal of Bacteriology 189, no. 1 (2006): 98–108. http://dx.doi.org/10.1128/jb.01347-06.

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ABSTRACT In Escherichia coli, at least 12 proteins, FtsZ, ZipA, FtsA, FtsE/X, FtsK, FtsQ, FtsL, FtsB, FtsW, FtsI, FtsN, and AmiC, are known to localize to the septal ring in an interdependent and sequential pathway to coordinate the septum formation at the midcell. The FtsEX complex is the latest recruit of this pathway, and unlike other division proteins, it is shown to be essential only on low-salt media. In this study, it is shown that ftsEX null mutations are not only salt remedial but also osmoremedial, which suggests that FtsEX may not be involved in salt transport as previously thought.
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Dissertations / Theses on the topic "FTSAQ"

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MURA, ANDREA. "Characterization of ftsA conditional lethal mutants shows that FtsA is required at early and late stages of cell division in Streptococcus pneumoniae." Doctoral thesis, Università degli Studi di Cagliari, 2015. http://hdl.handle.net/11584/266786.

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FtsA is an essential cell division protein fairly conserved among Eubacteria. It is an actin-like protein that structurally differs from actin because it lacks one of the four subdomains that is replaced by an additional one located elsewhere in the structure. FtsA localizes early at the cell division site, together or immediately after FtsZ, where it is needed both to tether FtsZ to the membrane and also to recruit to midcell the other cell division proteins. In agreement with this, FtsA interacts, at least, with itself, FtsZ, ZapA and the septal PBP, FtsI. Despite the advances in understand
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Vinkenvleugel, Thessa Marleen Floor. "Timing of FtsQ midcell localisation and its interaction with other cell division proteins." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2006. http://dare.uva.nl/document/20363.

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Szwedziak, Piotr Łukasz. "Biochemical and structural studies of the FtsZ:FtsA complex and polymerising abilities of the FtsA protein." Thesis, University of Cambridge, 2012. https://www.repository.cam.ac.uk/handle/1810/250346.

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A key step in bacterial cell division is the formation of the Z-ring composed of polymers of the tubulin-like protein FtsZ. The Z-ring constricts and through interaction with other components engages in remodelling the cell wall and membranes in order to yield two daughter cells. During this process, FtsZ is known to interact with FtsA, which is an early component of the Z-ring, and then recruits other components of the divisome, the cell division apparatus. Analysis of FtsA sequences revealed a conserved C-terminal motif, which is predicted to form an amphipathic helix and has been shown to l
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Paradis-Bleau, Catherine. "Développement accéléré de nouveaux inhibiteurs contre les protéines de division cellulaire FtsZ et FtsA de Pseudomonas aeruginosa." Thesis, Université Laval, 2003. http://www.theses.ulaval.ca/2003/21334/21334.pdf.

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L’impact des infections bactériennes couplé à l’émergence des mécanismes de résistance aux antibiotiques suscite un besoin urgent de nouvelles classes d’agents antibactériens. D’ailleurs, la résistance du pathogène opportuniste P. aeruginosa diminue l’efficacité de traitement et met en danger la vie des personnes infectées. Dans le but d’identifier de nouveaux antimicrobiens, nous exploitons la machinerie de division cellulaire bactérienne en tant que cible. Ainsi, les protéines de division cellulaire FtsZ et FtsA de P. aeruginosa ont été utilisées afin d’identifier des inhibiteurs protéiques
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Marshall, Laura Emma. "The identification and characterisation of novel antimicrobial targets in Burkholderia pseudomallei." Thesis, University of Exeter, 2012. http://hdl.handle.net/10036/4074.

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The bacterium Burkholderia pseudomallei causes the disease melioidosis, a significant public health threat in endemic regions and is a potential biowarfare agent. Treatment of melioidosis is intensive and prolonged and there is no licensed vaccine to protect against it. The aim of this study was to characterise novel targets for antimicrobials to improve treatment of melioidosis. A holistic down selection process was undertaken in order to identify a range of possible novel and exploitable antimicrobial targets in Burkholderia pseudomallei. Four targets: FtsA, FtsZ, MraW and TonB were selected
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Liu, Bing. "Roles of FtsN and DedD in Initiating E. Coli Cell Constriction." Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1409698564.

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Glimstedt, Linda. "Mass flows of per- and polyfluoroalkyl substances (PFASs) in a Swedish wastewater network and treatment plant." Thesis, Uppsala universitet, Institutionen för geovetenskaper, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-298118.

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Per- and polyfluoroalkyl substances (PFASs) are man-made substances that hold unique properties. They are not only oil- and water repellants but also very resistant to degradation. Due to these properties, the applications are endless and PFASs can be found in a wide range of industrial applications and commercial products. The effluents of wastewater treatment plants (WWTPs) have been pointed out as one of the major sources of PFASs in the environment. The main aim of this project was to evaluate the sources and the occurrence of PFASs in a wastewater network in a Swedish city and in the diff
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Redfearn, James C. "A Comprehensive Model of the Structure and Function of the FtsZ Ring of Escherichia coli." Kent State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=kent1460475643.

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GRENGA, LUCIA. "Study of the biological role of the protein-protein interaction in the divisome assembling and functionality." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2010. http://hdl.handle.net/2108/202281.

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L’incremento delle infezioni causate da batteri resistenti alle attuali terapie e la scarsità di farmaci efficaci per il loro trattamento spingono la comunità scientifica a cercare strategie innovative, per identificare nuove classi di farmaci antibatterici. Un modo per raggiungere questo obiettivo è quello di sviluppare farmaci che hanno nuovi meccanismi d’azione. Diverse caratteristiche delle proteine dell’apparato di divisione (o divisoma) batterico suggeriscono che esse potrebbero essere dei bersagli ideali per nuovi antimicrobici. Poiché la divisione cellulare richiede molteplici interaz
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Mazouni, Khallil. "Analyse de la photo régulation des gènes secA et fedl chez la cyanobactérie Synechocystis : analyse de la cytokinèse chez la cyanobactérie Synechocystis." Paris 6, 2003. http://www.theses.fr/2003PA066213.

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Books on the topic "FTSAQ"

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María del Pilar Honrubia Marcos. Clonación y caracterización de los genes murC, ftsQ y ftsZ de la agrupación génica dcw de Brevibacterium Lactofermentum ATCC 13869. Publicaciones Universidad de León, 2001.

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Book chapters on the topic "FTSAQ"

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Baranova, N., and M. Loose. "Single-molecule measurements to study polymerization dynamics of FtsZ-FtsA copolymers." In Methods in Cell Biology. Elsevier, 2017. http://dx.doi.org/10.1016/bs.mcb.2016.03.036.

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Melina Franco, Coradini, Cavicchioli Natalia, Chambo Ana Paula Sartório, Braccini Graciela Lucca, and Souza Maria Luiza Rodrigues. "INCLUSÃO DE FARINHA DE PEIXES DE DIFERENTES ESPÉCIES EM MASSA DE ESFIRRA ABERTA." In CIÊNCIA, TECNOLOGIA E INOVAÇÃO: DO CAMPO À MESA. Instituto Internacional Despertando Vocações, 2020. http://dx.doi.org/10.31692/978-65-88970-00-3.v.2.77-92.

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O objetivo foi elaborar esfirra aberta com a inclusão de farinha de peixe de diferentes espécies, para avaliar a composição química, microbiológica e sensorial. Para farinha de peixe, foram utilizadas carcaças de tilápia do Nilo, salmão, atum e sardinha. As carcaças de salmão, atum e sardinha foram submetidas ao cozimento. As carcaças de tilápia foram submetidas à salmouragem com extrato de alecrim defumados. Posteriormente todas as matérias primas foram prensadas, moídas, desidratadas, moídas novamente e embaladas a vácuo. Foram elaboradas quatro massas de esfirra com inclusão de 10% de farinha aromatizada de peixe (Tratamento1= controle –tilápia –FT; tratamento 2= Tilápia+Salmão –FTS; tratamento 3= tilápia+atum –FTA; tratamento 4= tilápia+sardinha -FTSA). A mistura foi de 80% farinha de tilápia e 10% da farinha das demais espécies. A inclusão de farinhas de espécies marinhas (atum, salmão e sardinha) na de tilápia aromatizada não apresentaram diferença no teor de umidade e cinzas, mas proporcionou um enriquecimento proteico e aumento no valor calórico das esfirras aberta prontas para consumo, e os teores de carboidratos foram reduzidos. As esfirras abertas prontas com a inclusão de FT e FTS foram melhores aceitas pelos provadores com maior intenção de compra destesprodutos em relação aos demais.
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