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Dissertations / Theses on the topic 'FTSAQ'

Author: Grafiati

Published: 5 June 2025

Last updated: 15 July 2025

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1

MURA, ANDREA. "Characterization of ftsA conditional lethal mutants shows that FtsA is required at early and late stages of cell division in Streptococcus pneumoniae." Doctoral thesis, Università degli Studi di Cagliari, 2015. http://hdl.handle.net/11584/266786.

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FtsA is an essential cell division protein fairly conserved among Eubacteria. It is an actin-like protein that structurally differs from actin because it lacks one of the four subdomains that is replaced by an additional one located elsewhere in the structure. FtsA localizes early at the cell division site, together or immediately after FtsZ, where it is needed both to tether FtsZ to the membrane and also to recruit to midcell the other cell division proteins. In agreement with this, FtsA interacts, at least, with itself, FtsZ, ZapA and the septal PBP, FtsI. Despite the advances in understand

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2

Vinkenvleugel, Thessa Marleen Floor. "Timing of FtsQ midcell localisation and its interaction with other cell division proteins." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2006. http://dare.uva.nl/document/20363.

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3

Szwedziak, Piotr Łukasz. "Biochemical and structural studies of the FtsZ:FtsA complex and polymerising abilities of the FtsA protein." Thesis, University of Cambridge, 2012. https://www.repository.cam.ac.uk/handle/1810/250346.

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A key step in bacterial cell division is the formation of the Z-ring composed of polymers of the tubulin-like protein FtsZ. The Z-ring constricts and through interaction with other components engages in remodelling the cell wall and membranes in order to yield two daughter cells. During this process, FtsZ is known to interact with FtsA, which is an early component of the Z-ring, and then recruits other components of the divisome, the cell division apparatus. Analysis of FtsA sequences revealed a conserved C-terminal motif, which is predicted to form an amphipathic helix and has been shown to l

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4

Paradis-Bleau, Catherine. "Développement accéléré de nouveaux inhibiteurs contre les protéines de division cellulaire FtsZ et FtsA de Pseudomonas aeruginosa." Thesis, Université Laval, 2003. http://www.theses.ulaval.ca/2003/21334/21334.pdf.

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L’impact des infections bactériennes couplé à l’émergence des mécanismes de résistance aux antibiotiques suscite un besoin urgent de nouvelles classes d’agents antibactériens. D’ailleurs, la résistance du pathogène opportuniste P. aeruginosa diminue l’efficacité de traitement et met en danger la vie des personnes infectées. Dans le but d’identifier de nouveaux antimicrobiens, nous exploitons la machinerie de division cellulaire bactérienne en tant que cible. Ainsi, les protéines de division cellulaire FtsZ et FtsA de P. aeruginosa ont été utilisées afin d’identifier des inhibiteurs protéiques

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5

Marshall, Laura Emma. "The identification and characterisation of novel antimicrobial targets in Burkholderia pseudomallei." Thesis, University of Exeter, 2012. http://hdl.handle.net/10036/4074.

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The bacterium Burkholderia pseudomallei causes the disease melioidosis, a significant public health threat in endemic regions and is a potential biowarfare agent. Treatment of melioidosis is intensive and prolonged and there is no licensed vaccine to protect against it. The aim of this study was to characterise novel targets for antimicrobials to improve treatment of melioidosis. A holistic down selection process was undertaken in order to identify a range of possible novel and exploitable antimicrobial targets in Burkholderia pseudomallei. Four targets: FtsA, FtsZ, MraW and TonB were selected

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6

Liu, Bing. "Roles of FtsN and DedD in Initiating E. Coli Cell Constriction." Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1409698564.

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7

Glimstedt, Linda. "Mass flows of per- and polyfluoroalkyl substances (PFASs) in a Swedish wastewater network and treatment plant." Thesis, Uppsala universitet, Institutionen för geovetenskaper, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-298118.

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Per- and polyfluoroalkyl substances (PFASs) are man-made substances that hold unique properties. They are not only oil- and water repellants but also very resistant to degradation. Due to these properties, the applications are endless and PFASs can be found in a wide range of industrial applications and commercial products. The effluents of wastewater treatment plants (WWTPs) have been pointed out as one of the major sources of PFASs in the environment. The main aim of this project was to evaluate the sources and the occurrence of PFASs in a wastewater network in a Swedish city and in the diff

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8

Redfearn, James C. "A Comprehensive Model of the Structure and Function of the FtsZ Ring of Escherichia coli." Kent State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=kent1460475643.

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9

GRENGA, LUCIA. "Study of the biological role of the protein-protein interaction in the divisome assembling and functionality." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2010. http://hdl.handle.net/2108/202281.

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L’incremento delle infezioni causate da batteri resistenti alle attuali terapie e la scarsità di farmaci efficaci per il loro trattamento spingono la comunità scientifica a cercare strategie innovative, per identificare nuove classi di farmaci antibatterici. Un modo per raggiungere questo obiettivo è quello di sviluppare farmaci che hanno nuovi meccanismi d’azione. Diverse caratteristiche delle proteine dell’apparato di divisione (o divisoma) batterico suggeriscono che esse potrebbero essere dei bersagli ideali per nuovi antimicrobici. Poiché la divisione cellulare richiede molteplici interaz

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10

Mazouni, Khallil. "Analyse de la photo régulation des gènes secA et fedl chez la cyanobactérie Synechocystis : analyse de la cytokinèse chez la cyanobactérie Synechocystis." Paris 6, 2003. http://www.theses.fr/2003PA066213.

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11

Huang, Jian-Yun, and 黃正宇. "Analysis of the ftsA P2 promoter region in Bacillus subtilis." Thesis, 1994. http://ndltd.ncl.edu.tw/handle/15669119651407900227.

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碩士<br>國立成功大學<br>微生物及免役學研究所<br>82<br>The asymmetric septum formation is a very signal and special character at the initiation of Bacillus subtilis sporulation. The septum formation genes, ftsA and ftsZ (or ftsAZ), are co- transcribed and controlled by three promoter (P1,P2 and P3) in Bacillus subtilis. The transcription of ftsAZ from P1 or P3 is required for the symmetric septum formation during vegetative stage. In contrast, expression of ftsAZ from P2 is only at sporulation phase. The σH,

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12

Huang, Zheng-Yu, and 黃正宇. "ANALYSIS OF THE ftsA P2 PROMOTER REGION IN BACILLUS SUBTILISZENG." Thesis, 1994. http://ndltd.ncl.edu.tw/handle/15570667921088847383.

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13

CHAUDHARY, ALOK. "EXPLORING THE ROLE OF FTSA FRAGMENT AS A POTENT ANTIMICROBIAL PEPTIDE." Thesis, 2016. http://dspace.dtu.ac.in:8080/jspui/handle/repository/15122.

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The quick increase in drug-resistant infections has dispense a significant challenge to antimicrobial therapies. The collapse of the most potent antibiotics to eliminate “superbugs” emphasizes the critical need to develop other control agents. All organism like bacteria, insect, plant and human being produce antimicrobial peptides (AMPs) as vital part of their nonspecific and immediately effective immunity against infection. Antimicrobial peptides are a key component of the innate defense of all species of life. Antimicrobial peptide has different characteristic like antiendotoxic, antibacteri

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14

Kubincová, Hana. "Kontrola buněčného dělení Streptococcus pneumoniae unikátní signální dráhou." Master's thesis, 2017. http://www.nusl.cz/ntk/nusl-368458.

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Genome of S. pneumoniae contains only one copy of the gene coding eukaryotic type protein kinase StkP and corresponding phosphatase PhpP. These two enzymes form a functional signaling pair regulating cell division, which could be used in the future for the design of new bacteriostatic compounds. Not only kinase and phosphatase are important components of the system, but also other members of this pathway - specific substrates of these enzymes. The identification of the Ser/Thr phosphoproteom with a focus on the membrane fraction provided information not only about already known substrates such

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15

Muzata, Tapiwa. "Examining consequences of principal-agent and corporate governance interactions in South Africa : a study of FTSA/JSE TOP40 companies." Thesis, 2018. http://hdl.handle.net/10500/25016.

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Abstract in Zulu, English and Afrikaans<br>This study examined the consequences of Principal-Agent and Corporate Governance interactions within South Africa’s FTSE/JSE Top40 listed companies from 2008 to 2016. The study’s objectives were to examine the prevalence of Principal-Agent and Corporate Governance problems, to ascertain potential costs of these problems, to establish their socio-economic consequences, and evaluate the effectiveness of the governance codes. The study is anchored in Principal-Agent theory. Mixed methods methodology was employed, specifically Concurrent and Exploratory S

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16

Bhatt, Brijesh Narayan. "Influence Of FtsH Protease On The Medial FtsZ Ring In Escherichia Coli." Thesis, 2011. https://etd.iisc.ac.in/handle/2005/2118.

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FtsH is an essential AAA family Zn++ metalloprotease of Escherichia coli, possessing ATPase-dependent chaperon activity and ATP-dependent protease activity. Heat shock transcription factor Sigma32, LpxC, SecY, and bacteriophage protein CII are some of the substrates of FtsH. Although FtsH is known to influence several cellular processes, the role of FtsH in bacterial cell division had not been identified. FtsZ is the principal cell division protein that marks the cell division site at mid-cell by forming a ring structure. Using a pair of ftsH-null and isogenic wild type strain of E. coli, ear

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17

Bhatt, Brijesh Narayan. "Influence Of FtsH Protease On The Medial FtsZ Ring In Escherichia Coli." Thesis, 2011. http://etd.iisc.ernet.in/handle/2005/2118.

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FtsH is an essential AAA family Zn++ metalloprotease of Escherichia coli, possessing ATPase-dependent chaperon activity and ATP-dependent protease activity. Heat shock transcription factor Sigma32, LpxC, SecY, and bacteriophage protein CII are some of the substrates of FtsH. Although FtsH is known to influence several cellular processes, the role of FtsH in bacterial cell division had not been identified. FtsZ is the principal cell division protein that marks the cell division site at mid-cell by forming a ring structure. Using a pair of ftsH-null and isogenic wild type strain of E. coli, ear

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