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Dissertations / Theses on the topic 'Fuel regulator'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

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1

Holmström, Johnny. "GOVERNOR ELECTRONICS FOR DIESEL ENGINES : High availability platform for real-time control and advanced fuel efficiency algorithms." Thesis, Mälardalens högskola, Akademin för innovation, design och teknik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-20282.

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Fossil fuel is a rare commodity and the combustion of this fuel results in negative environmental effects. This paper evaluates and validates the electronics needed to run intelligent algorithms to lower the fuel consumption for commercial vessels. This is done by integrating advanced fuel saving functions into an electronic device that controls the fuel injection of large diesel engines, as known as a diesel engine governor. The control system is classified as a safety critical system. This means that the electronics needs to be designed for fail safe operation. To allow for future research a

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2

Ondráček, Vladimír. "Regulace přívodu paliva turbohřídelového motoru." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2013. http://www.nusl.cz/ntk/nusl-230889.

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Elaborated project gives a complex design of backup hydro-mechanical unit for fuel supply of turboshaft engine TS 100. Required function of backup unit is to secure basic function of engine TS 100 over failure of primary electro-mechanical fuel system. Backup hydro-mechanical unit consists of hydrostatic fuel pump, centrifugal regulator, valve of maximum and minimum pressure, switch valve and signalization of activation hydro-mechanical unit. Parameters of hydro-mechanical unit are designed considering requested rotations speed of output shaft of engine and its allowed fluctuation. Calculation

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3

Толбатов, Андрій Володимирович, Андрей Владимирович Толбатов та Andrii Volodymyrovych Tolbatov. "Формування сигналу управління паливним регулятором ГТЕ за даними вимірювань потужності вироблення електроенергії". Thesis, Видавництво СумДУ, 2011. http://essuir.sumdu.edu.ua/handle/123456789/10467.

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4

Bastedo, Donald. "Regulation of bacterial chromosome replication origins through binding of 'response regulator' transcription factors and regulated proteolysis." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=96776.

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In order to proliferate, bacteria must coordinate chromosome replication and chromosome segregation with cell wall remodeling and other growth-related events. Selective inhibition of these incompletely understood control processes can enable antibiotic and therapeutic strategies. In my thesis, I examine molecularly similar mechanisms for regulating chromosome replication in alpha-proteobacterium Caulobacter crescentus and in the Actinobacterial human pathogen Mycobacterium tuberculosis. It was presumed that the response regulator CtrA, a global phospho-relay transcription factor, coordinates

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5

Chan, Yeuk Him. "A self-regulated passive fuel-feed system for passive direct methanol fuel cells /." View abstract or full-text, 2007. http://library.ust.hk/cgi/db/thesis.pl?MECH%202008%20CHAN.

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6

Huang, Bin. "Convertisseur continu-continu à rapport de transformation élevé pour applications pile à combustible." Thesis, Vandoeuvre-les-Nancy, INPL, 2009. http://www.theses.fr/2009INPL021N/document.

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Ce travail concerne l’étude, le dimensionnement et la réalisation d’un convertisseur continu-continu, associé à une source de type pile à combustible. Pour l’application envisagée, ce convertisseur a un rapport de transformation élevé voisin de 12. De plus l’ondulation de courant est limitée à 1% du courant moyen maximal. La mise en cascade de deux convertisseurs a été retenue pour obtenir un rapport de transformation élevé. Le premier étage est un Boost entrelacé associé à un filtre d’entrée de type L-C, qui permettent de réduire fortement l’ondulation du courant de source. Le second étage es

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7

Odland, Leslie Maureen. "Regulation of intramuscular fuel selection in humans during exercise." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq24420.pdf.

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8

Orfali, Karen Ann. "Regulation of cardiac fuel selection in response to dietary fat." Thesis, Queen Mary, University of London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321741.

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9

PROULX, KARINE. "NOVEL FUEL SENSING MECHANISMS IN THE REGULATION OF FOOD INTAKE." University of Cincinnati / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1155823274.

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10

Hinkson, Deborah Anne Rochelle. "The mechanism of protein kinase C regulation of the cystic fibrosis transmembrane conductance regulator /." Thesis, McGill University, 2000. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33407.

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The cystic fibrosis transmembrane conductance regulator (CFTR) is a plasma membrane chloride channel expressed in epithelial tissues. While protein kinase A (PKA) is the main activator of CFTR, patch clamp data have suggested a permissive role for PKC in modulating PKA responses. To clarify the role of PKC in CFTR regulation we used PCR mutagenesis to construct a CFTR mutant (9CA) in which the serines or threonines in nine consensus sequences for PKC phosphorylation were replaced by alanines. Its expression in stably transfected baby hamster kidney (BHK) cells was consistently lower than that

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11

Siam, Rania. "Mechanisms of C. crescentus regulation of chromosome replication by a cell cycle regulator protein." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=37838.

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Caulobacter crescentus divides asymmetrically to produce two different progeny, a swarmer progeny that is replication incompetent, and a stalked cell progeny that is replication competent. Upon cell division, a cell cycle regulator protein (CtrA) was identified only in the swarmer cells, and additional circumstantial evidence links this protein to being a repressor of chromosome replication. For example, this response regulator protein binds to five specific sites in the replication origin (Cori) designated [a-e]. We carefully studied the binding characteristics of both phosphorylated (CtrA~P)

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12

Xu, Minghong. "Regulation of two WW domain-containing transcriptional co-regulators in mammalian cells." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=21954.

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Abstract One of the major tasks in cancer research is to understand the regulation of transcription factors that are crucial in controlling cell proliferation, differentiation and apoptosis. To achieve this, transcriptional co-regulators and signaling pathways that control transcription factors have been extensively studied. One good example is the Runx family of proteins and two of their co-regulators, transcription co-activator with PDZ domain-binding motif (TAZ) and Yes-associated protein (YAP). TAZ and YAP are paralogous and serve as either co-activators or co-repressors depending on th

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13

Lee, Julie 1983. "Role of oxidative stress in the regulation of iron regulatory protein 2." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116073.

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Iron homeostasis is regulated by iron regulatory proteins, IRP1 and IRP2, which bind to iron responsive elements (IRE) in the mRNA of proteins of iron metabolism such as ferritin (iron storage). IRP2 undergoes iron-mediated degradation, and this pathway shares notable similarities with that of hypoxia-inducible factor 1 (HIF-1). It has been reported that oxidative stress marked by increased reactive oxygen species (ROS) signal HIF-1 stabilization in hypoxia. The role of ROS in IRP2 regulation is not well-established. We show that the degree of hypoxia induces differential effects on iron-media

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14

Trinh, Gina. "Novel regulator of tumour cell invasion:effect of Down-regulated renal cell carcinoma on cytoskeletal remodeling process." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=110515.

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DRR has been shown to be a novel regulator of malignant glial cell invasion. Isolated from a screen for up-regulated genes in hyper-invasive cells, DRR is expressed in the peripheral regions of high grade gliomas (Le et al., 2010). In culture, DRR+ cells have significantly enhanced invasion (3D collagen, 2D wound healing assays) and their motility is characterized by elongated, mesenchymal-like shape with rapidly extending/retracting protrusions. The study of malignant cell invasion is multi-faceted; one aspect of this dysregulated process involves cytoskeletal remodeling to promote motility.

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15

Huang, Bin. "Convertisseur continu-continu à rapport de transformation élevé pour applications pile à combustible." Electronic Thesis or Diss., Vandoeuvre-les-Nancy, INPL, 2009. http://www.theses.fr/2009INPL021N.

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Ce travail concerne l’étude, le dimensionnement et la réalisation d’un convertisseur continu-continu, associé à une source de type pile à combustible. Pour l’application envisagée, ce convertisseur a un rapport de transformation élevé voisin de 12. De plus l’ondulation de courant est limitée à 1% du courant moyen maximal. La mise en cascade de deux convertisseurs a été retenue pour obtenir un rapport de transformation élevé. Le premier étage est un Boost entrelacé associé à un filtre d’entrée de type L-C, qui permettent de réduire fortement l’ondulation du courant de source. Le second étage es

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16

Pitts, Michelle Lynn. "Design and analysis of subcritical experiments using fresh fuel assemblies." Diss., Georgia Institute of Technology, 1999. http://hdl.handle.net/1853/18375.

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17

McPhail, Lihong Lu. "Impacts of renewable fuel regulation and production on agriculture, energy, and welfare." [Ames, Iowa : Iowa State University], 2010. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3403859.

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18

Zhu, Hong 1968. "Reforming the China Securities Regulatory Commission : towards efficient and effective regulation of China's securities markets." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=20146.

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Today, China's securities markets are facing a number of regulatory problems. Many central regulatory problems arise from the fragmented regulatory system, which is not effectively structured to further the goals of securities legislation.<br>The purpose of this thesis is to review, and make recommendations in respect of, the securities regulatory system in China with particular attention to the regulatory role of the China Securities Regulatory Commission (CSRC).<br>After examining the characteristics of China's securities market development and identifying existing problems in the regulatory

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19

Li, Xiao Yu 1973. "Beta-adrenoreceptor mediated atria specific up-regulation of regulator of G-protein signaling (RGS) 5 in rodent atrium." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=80318.

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Due to a 195 fold cardiac overexpression of beta2-Adrenoreceptor (beta2AR), the hearts of transgenic TG4 mice are chronically overstimulated and, indeed, show little stimulatory response to further betaAR agonists. Previous investigations had suggested that signaling from the overexpressed beta 2ARs was dampened in the atria of TG4 mice. Regulators of G-protein Signaling (RGSs) are a family of negative regulators of G-Protein Coupled Receptor (GPCR) signaling that are frequently induced by GPCR stimulation. Using an RT-PCR based strategy, we have identified RGS5 as being a candidate RGS

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20

Vignos, Bridget A. "Influence of environmental regulation on automobile materials substitution decisions--the plastic fuel tank." Thesis, Massachusetts Institute of Technology, 1991. http://hdl.handle.net/1721.1/13421.

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21

Clarkberg, Jasper W. "Regulatory Uncertainty and the Natural Gas Industry in the US." Oberlin College Honors Theses / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=oberlin1495560884199246.

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22

MATTOS, LUIS A. T. de. "Proposta metodológica para a identificação e avaliação de aspectos e impactos ambientais em instalações nucleares do IPEN: estudo de caso aplicado ao Centro do Combustível Nuclear." reponame:Repositório Institucional do IPEN, 2013. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10595.

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Made available in DSpace on 2014-10-09T12:42:19Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:00:09Z (GMT). No. of bitstreams: 0<br>Tese (Doutoramento)<br>IPEN/T<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP

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23

Wilkinson, Nicole. "Regulation of murine erythropoiesis and metabolism by the iron regulatory protein1/hypoxia inducible factor 2 alpha pathway." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=121348.

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Iron is an essential nutrient for many biochemical functions within the body. However, its flexible redox potential is a "double edged" sword that makes it both essential for life but also renders it potentially toxic. As iron excretion is limited, iron absorption is tightly regulated. Systemic iron homeostasis is controlled through the hepatic hormone hepcidin. Iron and other stimuli control hepcidin transcription. When produced hepcidin circulates through out the body and binds to the cellular iron exporter ferroportin (FPN1) expressed on duodenal enterocytes, macrophages, and hepatocytes

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24

Millard, David A. (David Anthony). "Strategic analysis of technical, commercial, and regulatory influences on the commercialization of hydrogen fuel cell vehicles." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/104392.

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Thesis: M.B.A., Massachusetts Institute of Technology, Sloan School of Management, 2016. In conjunction with the Leaders for Global Operations Program at MIT.<br>Thesis: S.M. in Engineering Systems, Massachusetts Institute of Technology, School of Engineering, Institute for Data, Systems, and Society, 2016. In conjunction with the Leaders for Global Operations Program at MIT.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 46-47).<br>Increasing regulatory pressures are being applied to automotive manufacturers requiring them to reduce the negative impacts

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25

Brits, Derek. "The regulatory regime for bio–fuels in South Africa / Brits D." North-West University, 2011. http://hdl.handle.net/10394/8098.

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In this study bio–fuels are identified as a possible solution to the effects of climate change and a more secure supply of energy. It is determined if there exist any policies that could provide for the regulation of a bio–fuels industry in a sustainable manner. The management tools and regulatory measures used in the energy related policies to pursue the sustainable development of a secure energy sector are identified. Thereafter a discussion regarding the concept of strategic environmental assessment (SEA) follows to determine whether South African energy policies have been strategically dev

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26

Jean-Baptiste, Gaël. "Analysis of regulators of G protein signaling (RGS) 5 regulation and lysophosphatidic acid (LPA) signaling in muscle cells." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=98734.

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G protein-coupled Receptor (GPCR) signalling pathways are essential for all aspects of cell and organ physiology and the involved proteins work together to transmit signals across the plasma membrane. This process is highly regulated by a number of proteins including RGS (Regulators of G protein Signalling) proteins, which serve as GTPase-activating proteins for the Galpha subunit of heterotrimeric G proteins. Previous work in our lab has identified RGS5 as being expressed in the heart as well as being up regulated in the atria but not the ventricules of transgenic (TG4) mice that have a 195-f

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27

Kaboub, Fadhel Forstater Mathew. "A roadmap to full employment and price stability in developing countries the case of Tunisia /." Diss., UMK access, 2006.

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Thesis (Ph. D.)--Dept. of Economics and Social Science Consortium. University of Missouri--Kansas City, 2006.<br>"A dissertation in economics and social science consortium." Advisor: Mathew Forstater. Typescript. Vita. Title from "catalog record" of the print edition Description based on contents viewed Oct. 31, 2007. Includes bibliographical references (leaves 223-241). Online version of the print edition.

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28

Porter, Craig. "The impact of carnitine depletion on the regulation of fuel metabolism in rodent skeletal muscle." Thesis, University of Nottingham, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.580174.

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The body's carnitine pool is almost entirely confined to skeletal muscle where it plays a dual role in cellular energy metabolism. At rest and during moderate intensity exercise, carnitine is an obligatory cofactor in long chain fatty acid metabolism, whereas during intense contraction, carnitine plays a central role in the maintenance of the mitochondrial free Co enzyme A (CoASH) pool. Although carnitine supplementation has been touted as a means to alter skeletal muscle fuel metabolism for several decades, only recently has it been shown that skeletal muscle carnitine availability can be ele

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29

Laithwaite, David. "The role of the pyruvate dehydrogenase complex in the regulation of human skeletal muscle fuel metabolism." Thesis, University of Nottingham, 2009. http://eprints.nottingham.ac.uk/10992/.

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The pyruvate dehydrogenase complex (PDC) is the rate limiting step in the entry of glucose derived pyruvate into the tricarboxylic acid (TCA) cycle. As such it plays an important role in the control of the use of carbohydrate as the source of oxidative energy for skeletal muscle contraction. The first experimental chapter investigates the effect of dichloroacetate pre-treatment during low-intensity (<60% VO2max) exercise, below which it is suggested that increasing PDC activation and resting acetyl group availability via dichloroacetate (DCA) pre-treatment will be ineffective at reducing non-o

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30

Koops, Marten Derek. "Transcriptional regulation of human nonspecific cross-reacting antigen, a carcinoembryonic antigen gene family member up-regulated in colorectal carcinomas." Thesis, McGill University, 1997. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=20829.

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Human nonspecific cross-reacting antigen (NCA), a close relative of the tumour marker human carcinoembryonic antigen (CEA), is also an in vitro homotypic intercellular adhesion molecule capable of inhibiting differentiation when expressed ectopically in myoblasts. Moreover, NCA appears to be overexpressed at the transcriptional level to a greater extent and more frequently in colorectal carcinomas than CEA. This study examines the transcriptional control mechanisms responsible for orchestrating NCA expression. The region within 283 bp upstream of the translational start site of the NCA gene wa

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31

Hemlin, Karl. "Development of Sensor Concept to Regulate Fuel Supply During Priming of Water to Air Heater in Production." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-300905.

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The Water To Air heater (WTA) is a component that heats the interior and the engine of the truck by heating coolant through a combustion of diesel fuel. It is vital that the Water To Air heater is primed with fuel prior to using it in order for it to start when desired. Priming of the heater is done in production, which is where the trucks are built. This is done to ensure that there is fuel available to heat the coolant. However, the current priming process has too many weaknesses, it is sensitive to component changes and there are a number of uncertainties present. The goal of this thesis is

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32

Rodríguez, Morales Jorge Ernesto, and López Fernando Rodríguez. "Regulation, agro-energy policy and market evolution for renewable fuels in Brazil." Pontificia Universidad Católica del Perú, 2015. http://repositorio.pucp.edu.pe/index/handle/123456789/116056.

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The costs of oil dependence, the environmental external costs of fossil fuels, or the promotion of agricultural development, has justified a number of measures of state intervention to expand the domestic market of biofuels, assuming that state intervention is necessary and sufficient condition for achieving this aim. After analyzing the political and economic elements in the Brazilian ethanol sector in historical perspective, in this article we argue that the expansion or contraction of the market should not be understood as an effect of a particular policies determined by the regulatory stat

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33

Gessler, Dominic J. "Age-dependent rAAV Mediated Reconstitution of hASPA Reveals N-acetylaspartate Regulates Fuel Selection in the Central Nervous System." eScholarship@UMMS, 2020. https://escholarship.umassmed.edu/gsbs_diss/1110.

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N-acetylaspartate (NAA) is one of the most abundant molecules in the mammalian central nervous system (CNS). The current paradigm suggests that NAA is synthesized in neurons by the enzyme N-acetyltransferase 8-like (NAT8L) and hydrolyzed into aspartate and acetate by the enzyme aspartoacylase (ASPA) in oligodendrocytes. Although the function of NAA is not well understood, several hypotheses have been proposed since its discovery several decades ago. Among the most cited theory is the concept of acetate delivery to oligodendrocytes via NAA for the synthesis of fatty acids for myelin lipids and

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Silveira, Júnior Osmani Prates. "O mercado de combustíveis no Brasil: intervenção e regulação estatal." Núcleo de Pós-Graduação em Administração - NPGA, 2002. http://www.repositorio.ufba.br/ri/handle/ri/9510.

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Gorman, C. Allen, and Reyes D. A. Chavez. "Full Range Focus: How Regulatory Focus Influences the Relationship Between Leader Behavior and Subordinate Outcomes." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/2613.

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Excerpt: The current study explores these variables simultaneously to illustrate how both leader and follower characteristics influence organizational citizenship behavior (OCB) and counterproductive work behavior (CWB).

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36

Chatzopoulos, Aristeidis-Panagiotis. "Full envelope wind turbine controller design for power regulation and tower load reduction." Thesis, University of Strathclyde, 2011. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=18247.

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Gamache, Martin Christina. "In the Spirit of Full Disclosure: Maternal Characteristics that Encourage Adolescent Disclosure of Distressing Experiences." Thesis, University of Oregon, 2018. http://hdl.handle.net/1794/23087.

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The purpose of the current study was to investigate the dynamic process of disclosure within the adolescent–mother relationship by examining maternal characteristics that encourage adolescent disclosure of distressing experiences and risk factors that may interfere with mothers’ abilities to be supportive. A community sample of 66 mothers and their adolescent children (M = 14.31 years, 58% female) participated. The adolescents disclosed an emotionally distressing experience to their mothers for the first time. Mothers’ validating behaviors and emotional distress in response to their adoles

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38

Perron-Savard, Philippe. "Activation of bacterial response regulators." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=82406.

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In Salmonella typhimurium, PhoP is the response regulator of the PhoP/PhoQ two-component regulatory system. Gel filtration chromatography showed that PhoP exists as a mixture of monomer and dimer regardless of its phosphorylation state. Unphosphorylated PhOPHis (a mutant harboring a histidine tag at the C-terminus) was mostly monomeric, whereas PhoP His~P existed as a mixture of monomer and dimer. Binding of PhoP to the PhoP box was barely influenced by phosphorylation as determined by surface plasmon resonance. In contrast, phosphorylation of PhoPHis induced a 200% increase in PhoPHis

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Wang, Jia. "Design of a low noise, limited area and full on-chip power management for CMOS pixel sensors in high energy physics experiments." Phd thesis, Université de Strasbourg, 2012. http://tel.archives-ouvertes.fr/tel-00758209.

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What are the elementary particles and how did the universe originate are the main driving forces in the high energy physics. In order to further demonstrate the standard model and discover new physics, several detectors are built for the high energy physics experiments. CMOS pixel sensors (CPS) can achieve an attractive tradeoff among many performance parameters, such as readout speed, granularity, material budget, power dissipation, radiation tolerance and integrating readout circuitry on the same substrate, compared with the hybrid pixel sensors and charge coupled devices. Thus, the CPS is a

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40

Farrah, Jennifer. "CEACAMI as a negative regulator of T cell functions." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=81247.

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CEA-related cell adhesion molecule 1 (CEACAM1) is a member of the carcinoembryonic antigen (CEA) family that is expressed on activated T lymphocytes. Previous studies have reported both costimulatory and coinhibitory roles for this glycoprotein in T cell activation and effector functions. We have used a Ceacam1-/- mouse model to further explore this paradox. We demonstrate that CEACAM1 is not involved in T cell development or in migration of these lymphocytes to peripheral lymphoid organs. In vitro, CEACAM1 was observed to play an inhibitory role on T lymphocytes as it limits T cell pro

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Gocevski, Goran. "Interplay of Mye and Max with Epigenetic Regulator Bmi1." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114264.

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The polycomb group protein Bmi1 is an epigenetic regulator essential for the proliferation of many types of cancers. By impeding the expression of the tumor suppressor p53, Bmi1 is able to prevent apoptosis and senescence. c-Myc, a prominent oncogene, cooperates with Bmi1 to stimulate cellular transformation and tumorigenesis. Further investigation of the basic biological interplay between Bmi1 and c-Myc is crucial for our understanding of their tumorigenic ability. In my project I demonstrated that c-Myc and Bmi1 directly interact with each other and form nuclear foci. Overexpression of Max,

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Ionescu, Irina Gabriela. "Aircraft noise regulation." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=82660.

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Aircraft noise is one of the most controversial environmental concerns in the aviation industry, partly due to the difficulty in harmonizing countries' regulation regarding this issue. The purpose of this thesis is to analyze the ways in which aircraft noise is regulated at the national and international levels, and to compare the legislative responses to aircraft noise issues in Europe and North America. Each of the four main chapters of the thesis takes into consideration a different aspect of the problem. The first chapter describes the objective and subjective ways of measuring airc

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Nguyen, Ngoc phuong thao. "Metabolic engineering of clostridium acetobutylicum for the production of fuels and chemicals." Thesis, Toulouse, INSA, 2016. http://www.theses.fr/2016ISAT0051/document.

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À l'heure actuelle, il y a un regain d'intérêt pour Clostridium acetobutylicum, le biocatalyseur du procédé Weizmann historique, pour produire le n-butanol un produit chimique de commodité et un bio-carburant alternatif et renouvelable . Ce mémoire de thèse décrit un procédé de recombinaison homologue, utilisant plasmide réplicatif, pour la délétion ou l'introdu ction de gènes chez C. acetobutylicum avec une élimination facile des marqueurs utilisés. La souche de C. acetobutylicum cacl502upp et ce système de recombinaison homologue ont été utilisés dans d'autres expériences d'ingénierie pour o

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Nwaozuzu, Chijioke Ekezie. "The regulation of fuel retailing activities and its contribution to a rural development policy : lessons from the UK and Australian jurisdictions." Thesis, University of Dundee, 2010. https://discovery.dundee.ac.uk/en/studentTheses/a71dc0af-34ab-4c8a-a0d3-202064df04be.

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Limited competition among the few fuel retailers in rural and remote locations results in fuel pricing problems, such as high rural fuel prices and rural-urban fuel price differentials. Thus, the regulation of fuel retailing activities in these locations is expected to resolve these problems, and thus contribute to a rural development policy. These problems are of concern to governments and rural communities, primarily because high fuel prices generate significant multiplier effects on the cost of rural living and economic activities. Therefore, the purpose of this study was to investigate the

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Huynh, Kevin Weijian. "Structural Analysis of TRPV2 by Cryo-Electron Microscopy Reveals Regulatory Diversity Among the ThermoTRPV Channels." Case Western Reserve University School of Graduate Studies / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1467996438.

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Kapoustina, Oxana. "The identification of genes regulated by Interferon Regulatory Factors (IRF) 1 and 8 in the context of pathogen challenge by ChIP on Chip and genome wide transcription profiling approaches." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=86565.

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Interferon regulatory factors (IRFs) is a family of transcriptional regulators that are essential for cell differentiation and growth, oncogenesis and the regulation of immunity. IRF1 and IRF8 play a crucial role in immunity by regulating the differentiation of the cells of myeloid lineage, particularly the development of immune cells including macrophages, NK and dendritic cells. Both transcription factors are essential for the resistance to viral and bacterial infections. We optimized the chromatin immunoprecipitation (ChIP) technique to be used with IRF8 and IRF1 antibodies in a J774 line

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Ranger, Jill. "Stat3 as a multifaceted regulator of mammary tumourigenesis and metastasis." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=110488.

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Many forms of cancer express activated Stat3, a pleiotropic transcription factor that is implicated in pro-tumourigenic signaling in a variety of cancer cell lines, revealing that it may be important for tumour onset, progression, and malignancy. Yet, the role of Stat3 in the context of tumourigenesis in vivo is still unclear. Downstream of an activated form of ErbB2, we have demonstrated that Stat3 is dispensable for in vivo tumour initiation but is crucial for metastasis. Conversely, the loss of Stat3 in a novel inducible model of PyVMT-driven tumourigenesis revealed that Stat3 is necessa

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Ajlan, Abdulrazag. "Characterising DRR as a novel regulator of focal adhesion dynamics." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116975.

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Intracranial gliomas are the most common primary brain tumors. Despite advances in medicine, patient outcomes have not changed significantly over the last century. The invasive behavior of these cells is the main reason for treatment failure. Cancer invasion and cell motility are topics under intense investigation in cancer research. However, they are less studied in gliomas and the literature describing the molecular mechanisms which govern glioma cells motility is lagging.We have recently reported Down Regulated in Renal cell carcinoma (DRR) as a novel modulator of glioma invasion and migrat

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Tuason, Maria Clarita. "Functional analysis of Proteolipid Protein regulatory sequence." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=101805.

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Myelin is an evolutionarily late acquisition of the vertebrate nervous system which speeds electrochemical signaling in mature nerve fibers by providing insulation in the form of a lipid-rich multilammelar sheath. Proteolipid Protein (PLP) is the most abundant protein in mature mammalian central nervous system myelin where it serves as a structural component in addition to other yet undefined roles. It is coordinately regulated at the transcriptional level with other myelin genes such as Myelin Basic Protein (MBP). The major components of MBP transcriptional regulation have been defined using

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Wilds, Roy. "Dynamics, function and evolution of regulatory networks." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=66809.

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Biochemical regulatory networks are involved in many essential processes of life, such as maintaining homeostatic conditions, cell-cycle division, and responding to environmental stimuli. Such networks contain a staggering degree of complexity, inhibiting our ability to understand how they function. Two major challenges in quantitative biology are addressed in this thesis. First, the problem of identifying regulatory models from observational data. Second, characterizing how regulatory networks evolve. Making use of a simple regulatory model that is based on piecewise linear

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