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Journal articles on the topic 'Full Mouth Disinfection'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 April 2022

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1

Jervøe-Storm, Pia-Merete, Jörg Eberhard, and Søren Jepsen. "Full-Mouth-Disinfection." Zahnmedizin up2date 1, no. 1 (October 2007): 13–28. http://dx.doi.org/10.1055/s-2007-965436.

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2

Sharpe, Geoffrey, and Robin A. Seymour. "Full-Mouth Disinfection." Dental Update 37, no. 7 (September 2, 2010): 435–44. http://dx.doi.org/10.12968/denu.2010.37.7.435.

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3

Manjunatha, Vinayaka Ambujakshi. "Full-mouth disinfection-A literature update." International Dental Journal of Student's Research 10, no. 1 (March 15, 2022): 1–4. http://dx.doi.org/10.18231/j.idjsr.2022.001.

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Non-surgical periodontal disease therapy has traditionally been performed through a series of sessions by a jaw quadrant or sextant. Reinfection from untreated periodontal pockets, tongue, and tonsils might develop at this time. In contrast, in the full-mouth disinfection (FMD) technique, all teeth's root instrumentation is finished within 24 hours and comprises, Cleaning the tongue and using chlorhexidine on a regular basis.
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4

Pockpa, Ange Désiré, Assem Soueidan, Pauline Louis, Nadin Thérèse Coulibaly, Zahi Badran, and Xavier Struillou. "Twenty Years of Full-Mouth Disinfection: The Past, the Present and the Future." Open Dentistry Journal 12, no. 1 (May 31, 2018): 435–42. http://dx.doi.org/10.2174/1874210601812010435.

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Background: Conventional periodontal treatment, performed quadrant by quadrant in multiple visits, was re-evaluated in the early 1990s when the full-mouth disinfection concept was introduced. Over the years, several modifications to the full-mouth disinfection approach have been suggested. Objective: The purpose of this article is to review the evolution of full-mouth disinfection during the past 20 years, to specify its indications and to consider the prospects for this approach. Materials and Methods: An electronic and manual search of the literature, ending in December 2016, was performed by two independent researchers. Only pivotal studies and randomized controlled clinical trials published in the English language that evaluated a new approach to full-mouth disinfection were selected. Results: According to the studies included in our analysis (21 articles), several modified full-mouth disinfection protocols have been designed including: full-mouth treatment without chlorhexidine, the extension of hygiene methods and an increase in the duration of post-treatment chlorhexidine use, the replacement of chlorhexidine with other antiseptics, supplementation with antibiotics or probiotics, full-mouth antimicrobial photodynamic therapy and one-stage full-mouth disinfection combined with a periodontal dressing. Conclusion: Since 1995, several modifications have been suggested to improve the effectiveness of full-mouth disinfection. The majority of the studies demonstrate that the results obtained with full-mouth disinfection and its variants are equivalent to each other and to those obtained with the conventional quadrant method. Currently, the selection of this technique remains empirical and depends on the preferences of the practitioner and the patient. In the future, a patient-centered approach should be the best indication for the use of this technique.
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5

Cho, Ik Hyun, Ui Won Jung, Jeong Heon Cha, Joong Su Kim, Dae Sil Lee, Chong Kwan Kim, and Seong Ho Choi. "Clinical evaluation of full mouth disinfection therapy." Journal of the Korean Academy of Periodontology 35, no. 3 (2005): 597. http://dx.doi.org/10.5051/jkape.2005.35.3.597.

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6

Murray, Sarah. "Full mouth disinfection: what’s it all about?" Dental Nursing 3, no. 7 (August 2007): 388–91. http://dx.doi.org/10.12968/denn.2007.3.7.29736.

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7

Lee, Shin Hwa, Ok Su Kim, Young Joon Kim, and Hyun Ju Chung. "Clinical short-term effects of full-mouth disinfection." Journal of the Korean Academy of Periodontology 37, no. 3 (2007): 613. http://dx.doi.org/10.5051/jkape.2007.37.3.613.

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8

Apatzidou, Danae Anastasia. "One stage full-mouth disinfection ? Treatment of choice?" Journal of Clinical Periodontology 33, no. 12 (December 2006): 942–43. http://dx.doi.org/10.1111/j.1600-051x.2006.01021.x.

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9

Teughels, Wim, Christel Dekeyser, Mark Van Essche, and Marc Quirynen. "One-stage, full-mouth disinfection: fiction or reality?" Periodontology 2000 50, no. 1 (June 2009): 39–51. http://dx.doi.org/10.1111/j.1600-0757.2008.00292.x.

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10

Quirynen, Marc, Wim Teughels, and Daniel van Steenberghe. "Impact of antiseptics on one-stage, full-mouth disinfection." Journal of Clinical Periodontology 33, no. 1 (January 2006): 49–52. http://dx.doi.org/10.1111/j.1600-051x.2005.00868.x.

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11

Lowden, C., and S. Termaat. "Full-Mouth-Disinfection - Eine Behandlungsmodifikation im Zeitmanagement der geschlossenen Parodontaltherapie." ZWR - Das Deutsche Zahnärzteblatt 116, no. 07/08 (July 2007): 344–50. http://dx.doi.org/10.1055/s-2007-986164.

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12

Sagar, Anjana. "Full Mouth versus Quadrant Treatment in Chronic Periodontitis." Primary Dental Journal 3, no. 3 (September 2014): 66–69. http://dx.doi.org/10.1308/205016814812736853.

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Aim The aim of this review is to discuss the evidence for the management of chronic periodontitis, including methods of non-surgical therapy such as full mouth disinfection, full mouth debridement and conventional quadrant-by-quadrant therapy. Methods Manual searches of Medline and Embase databases provided the relevant studies. Results Multiple randomised controlled trials (RCTs) selected for the paper failed to show any significant differences between the quadrant-wise treatment and full mouth debridement and modalities. Practical implications This review demonstrates that there is no known difference in treatment outcomes between full mouth debridement and traditional quadrant therapy. Further RCTs are necessary to assess clinical effectiveness of chemical adjunct use.
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13

Bollen, Curd M. L., Betty N. A. Vandekerckhove, William Papaioannou, Johan Van Eldere, and Marc Quirynen. "Full- versus partial-mouth disinfection in the treatment of periodontal infections." Journal of Clinical Periodontology 23, no. 10 (October 1996): 960–70. http://dx.doi.org/10.1111/j.1600-051x.1996.tb00519.x.

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14

Cortelli, José Roberto, Marcos Vinicius Moreira de Castro, Rodrigo Dalla Pria Balejo, Camila Oliveira de Alencar, Antonio Carlos Gargioni Filho, Sheila Cavalca Cortelli, and Fernando Oliveira Costa. "Clinical and microbiological evaluation of one-stage full-mouth disinfection: a short-term study." Revista de Odontologia da UNESP 42, no. 4 (August 2013): 298–303. http://dx.doi.org/10.1590/s1807-25772013000400010.

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INTRODUCTION: Patients seem to adhere better to short-term periodontal treatment schemes. Besides, time-reduced treatments are more cost-effective. However, the degree of benefits related to this type of treatment still requires additional investigations. AIM: The present short-term study evaluated clinical and microbiological outcomes, from baseline to 3-months, of chronic periodontitis subjects treated by the one-stage full-mouth disinfection protocol. MATERIAL AND METHOD: Sixteen chronic periodontitis subjects (mean-age 49.87 ± 8.22) who met inclusion/exclusion criteria were included. A calibrated examiner measured whole-mouth plaque and gingival indices, periodontal pocket depth and clinical attachment level at baseline and at 3-months. Subgingival samples were also collected from the 5 most diseased periodontal sites to determine total bacterial load and levels of P. gingivalis and S. oralis by real time qPCR. Periodontal treatment consisted of full-mouth manual debridement plus wide intraoral use of chlorhexidine in gel and solution. Additionally, after debridement, individuals rinsed 0.12% chlorhexidine at home twice a day for the following 2 months. Data monitored were compared by paired Student-t test (p<0.05). RESULT: Statistical analysis revealed that, in general, one-stage full-mouth disinfection treatment provided significant clinical and microbiological improvements at 3-months. Total bacterial load showed one of the most pronounced reductions from baseline to 3-months (p=0.0001). Also, subgingival levels P. gingivalis and S. oralis reduced overtime. CONCLUSION: After a short period of monitoring, chronic periodontitis subjects showed clinical and microbial improvements following one-stage full-mouth disinfection treatment.
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15

G. Soares, Léo, Lisiane Castagna, Sérgio C. Weyne, Denise G. Silva, Márcio E. V. Falabella, and Eduardo M. B. Tinoco. "Effectiveness of full- and partial-mouth disinfection on halitosis in periodontal patients." Journal of Oral Science 57, no. 1 (2015): 1–6. http://dx.doi.org/10.2334/josnusd.57.1.

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16

Papaioannou, W., C. M. L. Bollen, and M. Quirynen. "One-stage Full-mouth Disinfection to Overcome Intra-oral Transmission of Periodontopathogens." Anaerobe 3, no. 2-3 (April 1997): 163–68. http://dx.doi.org/10.1006/anae.1997.0097.

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17

Hamed, Ahmed. "Non Surgical Treatment Of Chronic Periodontitis By Two Strategies Of Full Mouth Disinfection." Egyptian Dental Journal 64, no. 2 (April 1, 2018): 1345–51. http://dx.doi.org/10.21608/edj.2018.77392.

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18

Aimetti, Mario, Federica Romano, Nicoletta Guzzi, and Gianfranco Carnevale. "One-Stage Full-Mouth Disinfection as a Therapeutic Approach for Generalized Aggressive Periodontitis." Journal of Periodontology 82, no. 6 (June 2011): 845–53. http://dx.doi.org/10.1902/jop.2010.100468.

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19

Bae, Soo-Min, Ju-Youn Lee, Jeom-Il Choi, and Sung-Jo Kim. "The effect of a full mouth disinfection on oral malodor in chronic periodontitis patients." Journal of the Korean Academy of Periodontology 36, no. 4 (2006): 829. http://dx.doi.org/10.5051/jkape.2006.36.4.829.

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20

Vishwanath, Anju, AenaJain Pundir, Siddharth Pundir, M. Swati, Saket Banchhor, and Saba Jabee. "One-stage full mouth disinfection using 20% propolis hydroalcoholic solution: A clinico-microbiologic study." Contemporary Clinical Dentistry 8, no. 3 (2017): 416. http://dx.doi.org/10.4103/ccd.ccd_544_17.

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21

Pundir, AenaJain, Siddharth Pundir, R. K. Yeltiwar, Sana Farista, V. Gopinath, and T. S. Srinivas. "Treatment of drug-induced gingival overgrowth by full-mouth disinfection: A non-surgical approach." Journal of Indian Society of Periodontology 18, no. 3 (2014): 311. http://dx.doi.org/10.4103/0972-124x.134567.

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22

Nassar, Patrícia Oehlmeyer, Rodrigo Poleto, Camila Saturnino Salvador, Francielly Andressa Felipetti, and Carlos Augusto Nassar. "One-stage full-mouth disinfection and basic periodontal treatment in patients with diabetes mellitus." Journal of Public Health 22, no. 1 (October 13, 2013): 81–86. http://dx.doi.org/10.1007/s10389-013-0596-1.

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23

Quirynen, Marc, Marc De Soete, Geert Boschmans, Martine Pauwels, Wim Coucke, Wim Teughels, and Daniel van Steenberghe. "Benefit of “one-stage full-mouth disinfection” is explained by disinfection and root planing within 24 hours: a randomized controlled trial." Journal of Clinical Periodontology 33, no. 9 (September 2006): 639–47. http://dx.doi.org/10.1111/j.1600-051x.2006.00959.x.

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24

Soete, Marc De, Claudio Mongardini, Martine Pauwels, Anne Haffajee, Sigmund Socransky, Daniel van Steenberghe, and Marc Quirynen. "One-Stage Full-Mouth Disinfection. Long-Term Microbiological Results Analyzed by Checkerboard DNA-DNA Hybridization." Journal of Periodontology 72, no. 3 (March 2001): 374–82. http://dx.doi.org/10.1902/jop.2001.72.3.374.

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25

Koshy, Geena, Esmonde f. Corbet, and Isao Ishikawa. "A full-mouth disinfection approach to nonsurgical periodontal therapy - prevention of reinfection from bacterial reservoirs." Periodontology 2000 36, no. 1 (October 2004): 166–78. http://dx.doi.org/10.1111/j.1600-0757.2004.03678.x.

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26

Keestra, Johan A. J., Wim Coucke, and Marc Quirynen. "One-stage full-mouth disinfection combined with a periodontal dressing: a randomized controlled clinical trial." Journal of Clinical Periodontology 41, no. 2 (December 11, 2013): 157–63. http://dx.doi.org/10.1111/jcpe.12199.

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27

Anna, Maria Genovesi, Marconcini Simone, Ricci Massimiliano, Marchisio Olivia, Covani Francesca, and Covani Ugo. "Evaluation of a decontamination protocol prior to a full-mouth disinfection procedure: A randomised clinical study." Journal of Dentistry and Oral Hygiene 6, no. 7 (November 30, 2014): 77–84. http://dx.doi.org/10.5897/jdoh2014.0126.

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28

Giraudi, Marta, Gian Marco Piccoli, and Mario Aimetti. "Full Mouth Disinfection e terapia antimicrobica sistemica: un caso clinico a 5 anni di follow-up." Dental Cadmos 86, no. 08 (August 2018): 739. http://dx.doi.org/10.19256/d.cadmos.08.2018.12.

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29

Aimetti, Mario, Federica Romano, Nicoletta Guzzi, and Gianfranco Carnevale. "Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial." Journal of Clinical Periodontology 39, no. 3 (January 4, 2012): 284–94. http://dx.doi.org/10.1111/j.1600-051x.2011.01795.x.

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30

Schulz, Susanne, Jamal M. Stein, Anne Schumacher, David Kupietz, Sareh S. Yekta-Michael, Florian Schittenhelm, Georg Conrads, Hans-Günter Schaller, and Stefan Reichert. "Nonsurgical Periodontal Treatment Options and Their Impact on Subgingival Microbiota." Journal of Clinical Medicine 11, no. 5 (February 23, 2022): 1187. http://dx.doi.org/10.3390/jcm11051187.

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Background: Different periodontal treatment methods (quadrant-wise debridement, scaling and root planing (Q-SRP), full-mouth scaling (FMS), full-mouth disinfection (FMD), and FMD with adjuvant erythritol air-polishing (FMDAP)) were applied in periodontitis patients (stage III/IV). The study objective (substudy of ClinicalTrials.gov Identifier: NCT03509233) was to compare the impact of treatments on subgingival colonization. Methods: Forty patients were randomized to the treatment groups. Periodontal parameters and subgingival colonization were evaluated at baseline and 3 and 6 months after treatment. Results: Positive changes in clinical parameters were recorded in every treatment group during the 3-month follow-up period, but did not always continue. In three groups, specific bacteria decreased after 3 months; however, this was associated with a renewed increase after 6 months (FMS: Porphyromonas gingivalis; FMD: Eubacterium nodatum, Prevotella dentalis; and FMDAP: uncultured Prevotella sp.). Conclusions: The benefit of all clinical treatments measured after 3 months was associated with a decrease in pathogenic bacteria in the FMS, FMD, and FMDAP groups. However, after 6 months, we observed further improvement or some stagnation in clinical outcomes accompanied by deterioration of the microbiological profile. Investigating the subgingival microbiota might help appraise successful periodontal treatment and implement individualized therapy.
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31

Rajeev, Vini, Rajeev Arunachalam, Ramesh Kumaresan, and Sarath B. Kurra. "Clinical and Biochemical Valuation of Enzymatic and Nonenzymatic Stress Markers Following Full-mouth Disinfection in Aggressive Periodontitis." Journal of Contemporary Dental Practice 20, no. 8 (2019): 952–56. http://dx.doi.org/10.5005/jp-journals-10024-2622.

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32

Romani Vestman, N., P. Hasslöf, M. K. Keller, E. Granström, S. Roos, S. Twetman, and C. Stecksén-Blicks. "Lactobacillus reuteri Influences Regrowth of Mutans Streptococci after Full-Mouth Disinfection: A Double-Blind, Randomised Controlled Trial." Caries Research 47, no. 4 (2013): 338–45. http://dx.doi.org/10.1159/000347233.

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33

Quirynen, M., C. M. L. Bollen, B. N. A. Vandekerckhove, C. Dekeyser, W. Papaioannou, and H. Eyssen. "Full- vs. Partial-mouth Disinfection in the Treatment of Periodontal Infections: Short-term Clinical and Microbiological Observations." Journal of Dental Research 74, no. 8 (August 1995): 1459–67. http://dx.doi.org/10.1177/00220345950740080501.

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34

Padhye, Ashvini M., Vineet V. Kini, and Arjumand Farooqui. "Comparative Evaluation of Two Different One-stage Full-mouth Disinfection Protocols using BANA Assay: A Randomized Clinical Study." Journal of Contemporary Dental Practice 20, no. 8 (2019): 963–69. http://dx.doi.org/10.5005/jp-journals-10024-2623.

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35

Quirynen, Marc, Claudio Mongardini, Martine Pauwels, Curd M. L. Bollen, Johan Van Eldere, and Daniel Van Steenberghe. "One Stage Full- Versus Partial-Mouth Disinfection in the Treatment of Chronic Adult or Generalized Early-Onset Periodontitis." Journal of Periodontology 70, no. 6 (June 1999): 646–56. http://dx.doi.org/10.1902/jop.1999.70.6.646.

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36

Lee, Shin-Hwa, Young-Joon Kim, Hyun-Ju Chung, and Ok-Su Kim. "The clinical effects of modified full-mouth disinfection in the treatment of moderate to severe chronic periodontitis patients." Journal of the Korean Academy of Periodontology 39, Suppl (2009): 239. http://dx.doi.org/10.5051/jkape.2009.39.s.239.

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37

Assis, RIF, MF Silva-Junior, MS Santos, TCR Pereira, ACR Feitosa, and SL Azevedo-Vaz. "Radiographic Bone Evaluation after Periodontal Full Mouth Disinfection Treatment in Women Undergoing Chemotherapy or Hormone Therapy with Tamoxifen." Pesquisa Brasileira em Odontopediatria e Clínica Integrada 16, no. 1 (2016): 219–27. http://dx.doi.org/10.4034/pboci.2016.161.23.

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38

Bollen, Curd M. L., Claudio Mongardini, William Papaioannou, Daniel Steenberghe, and Marc Quirynen. "The effect of a one-stage full-mouth disinfection on different intra-oral niches Clinical and microbiological observations." Journal of Clinical Periodontology 25, no. 1 (January 1998): 56–66. http://dx.doi.org/10.1111/j.1600-051x.1998.tb02364.x.

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39

Quirynen, Marc, Claudio Mongardini, Marc De Soete, Martine Pauwels, Wim Coucke, Johan Van Eldere, and Daniel Van Steenberghe. "The rôle of chlorhexidine in the one-stage full-mouth disinfection treatment of patients with advanced adult periodontitis." Journal of Clinical Periodontology 27, no. 8 (August 2000): 578–89. http://dx.doi.org/10.1034/j.1600-051x.2000.027008578.x.

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40

Parihar, AnujSingh, Sachin Bhagat, Parthivi Singh, Gurpreet Kaur, Harsh Takkar, and Rathi Rela. "Assessment of levels of plasma oxidative stress in patient having aggressive periodontitis before and after full mouth disinfection." Journal of Pharmacy And Bioallied Sciences 13, no. 5 (2021): 432. http://dx.doi.org/10.4103/jpbs.jpbs_599_20.

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41

Vandekerckhove, Betty N. A., Curd M. L. Bollen, Chris Dekeyser, Paul Darius, and Marc Quirynen. "Full- Versus Partial-Mouth Disinfection in the Treatment of Periodontal Infections. Long-Term Clinical Observations of a Pilot Study." Journal of Periodontology 67, no. 12 (December 1996): 1251–59. http://dx.doi.org/10.1902/jop.1996.67.12.1251.

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42

Hanaoka, Masaki, and Chikako Hanaoka. "Report of a case of localized chronic periodontitis treated by periodontal regenerative therapy after full mouth disinfection with antibiotics." Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) 59, no. 2 (2017): 87–99. http://dx.doi.org/10.2329/perio.59.87.

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43

Afacan, Beral, Serhat Çınarcık, Ali Gürkan, Güven Özdemir, Harika Atmaca İlhan, Caner Vural, Timur Köse, and Gülnur Emingil. "Full‐mouth disinfection effects on gingival fluid calprotectin, osteocalcin, and N‐telopeptide of Type I collagen in severe periodontitis." Journal of Periodontology 91, no. 5 (March 14, 2020): 638–50. http://dx.doi.org/10.1002/jper.19-0445.

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44

Santos, Vanessa R., Jadson A. Lima, Tamires S. Miranda, Tiago E. D. Gonçalves, Luciene C. Figueiredo, Marcelo Faveri, and Poliana M. Duarte. "Full-mouth disinfection as a therapeutic protocol for type-2 diabetic subjects with chronic periodontitis: Twelve-month clinical outcomes. A randomized controlled clinical trial." Journal of Clinical Periodontology 40, no. 2 (January 11, 2013): 155–62. http://dx.doi.org/10.1111/jcpe.12040.

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45

De Soete, M., C. Dekeyser, M. Pauwels, W. Teughels, D. van Steenberghe, and M. Quirynen. "Increase in Cariogenic Bacteria after Initial Periodontal Therapy." Journal of Dental Research 84, no. 1 (January 2005): 48–53. http://dx.doi.org/10.1177/154405910508400108.

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This study examined the hypothesis of an intra-oral shift, during initial periodontal therapy, from a periopathogenic to a cariogenic flora. Seventy-one patients with periodontitis were randomly allocated to one of the following treatment strategies: (1) scaling and root planing, quadrant by quadrant, at two-week intervals (NC); (2) full-mouth scaling and root planing within 24 hrs (FRP); or (3) full-mouth disinfection within 24 hrs, including antiseptics [chlorhexidine (CHX) or amine fluoride/stannous fluoride (F) for 2 mos, or CHX for 2 mos followed by F for 6 mos (CHX+F)]. At baseline and after 2, 4, and 8 mos, bacterial samples were taken from supra- and subgingival plaque, saliva, and tongue. The detection frequencies and relative proportions of Streptococcus mutans increased in the NC and FRP groups, but decreased in the F group. In the CHX group, these species disappeared temporarily, but they disappeared for the entire 8 mos in the CHX+F group. These observations were similar for all sample locations. The periopathogens decreased in all groups. This finding confirms the abovementioned hypothesis and indicates a need for caries prophylactic regimens.
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46

Cortelli, Sheila Cavalca, José Roberto Cortelli, Marinella Holzhausen, Gilson Cesar Nobre Franco, Renato Zanotta Rebelo, Alan Salinas Sonagere, Celso da Silva Queiroz, and Fernando Oliveira Costa. "Essential oils in one-stage full-mouth disinfection: double-blind, randomized clinical trial of long-term clinical, microbial and salivary effects." Journal of Clinical Periodontology 36, no. 4 (April 2009): 333–42. http://dx.doi.org/10.1111/j.1600-051x.2009.01376.x.

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47

Fang, H., M. Han, Q. L. Li, C. Y. Cao, R. Xia, and Z. H. Zhang. "Comparison of full-mouth disinfection and quadrant-wise scaling in the treatment of adult chronic periodontitis: a systematic review and meta-analysis." Journal of Periodontal Research 51, no. 4 (October 19, 2015): 417–30. http://dx.doi.org/10.1111/jre.12326.

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48

Campisciano, Giuseppina, Annamaria Toschetti, Manola Comar, Rosanna Di Taranto, Federico Berton, and Claudio Stacchi. "Shifts of subgingival bacterial population after nonsurgical and pharmacological therapy of localized aggressive periodontitis, followed for 1 year by Ion Torrent PGM platform." European Journal of Dentistry 11, no. 01 (January 2017): 126–29. http://dx.doi.org/10.4103/ejd.ejd_309_16.

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ABSTRACTThe possibility of targeting the hypervariable region V3 of the 16S rRNA gene using Ion Torrent Personal Genome Machine (PGM) could provide a complete analysis of subgingival plaque samples, potentially able to identify microbiological species missed by culture-based methods. A 16-year-old female smoker patient, affected by localized aggressive periodontitis, underwent a full-mouth disinfection protocol and was inserted in a 3-month recall program. Microbiological samples were collected at baseline and at 30, 100, 365 days follow-up and analyzed by Ion Torrent PGM. Capnocytophaga, Fusobacterium, Prevotella, and Treponema were the most represented pathogens at baseline. Nonsurgical treatment and systemic antibiotics drastically lowered the anaerobic species, and their presence remained limited after 100 days, while a consistent recolonization by anaerobic bacteria was detected at 365 days. The patient showed a general improvement of periodontal conditions. Differently from polymerase chain reaction and other microarray techniques, Ion Torrent performs a quantitative analysis of the microbiota, irrespective of the searched species. An accurate definition of the shifts of the bacterial community might help periodontal researchers for a better understanding of the impact of different treatment approaches or in intercepting nonresponsive conditions.
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49

Marconcini, Simone, Enrica Giammarinaro, Saverio Cosola, Giacomo Oldoini, Annamaria Genovesi, and Ugo Covani. "Effects of Non-Surgical Periodontal Treatment on Reactive Oxygen Metabolites and Glycemic Control in Diabetic Patients with Chronic Periodontitis." Antioxidants 10, no. 7 (June 30, 2021): 1056. http://dx.doi.org/10.3390/antiox10071056.

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Periodontal infection may contribute to poor glycemic control and systemic inflammation in diabetic patients. The aim of the present study is to evaluate the efficacy of non-surgical periodontal treatment in diabetic patients by measuring oxidative stress outcomes. Sixty diabetic patients with periodontitis were enrolled, treated with scaling and full-mouth disinfection, and randomly prescribed chlorhexidine mouthwash, antioxidant mouthwash, or ozone therapy. Reactive oxygen metabolites (ROMs), periodontal parameters, and glycated hemoglobin were measured at baseline and then at 1, 3, and 6 months after. At baseline, all patients presented with pathologic levels of plasmatic ROM (388 ± 21.36 U CARR), higher than the normal population. Probing depth, plaque index, and bleeding on probing values showed significant clinical improvements after treatment, accompanied by significant reductions of plasma ROM levels (p < 0.05). At the 6-month evaluation, the mean ROM relapsed to 332 ± 31.76 U CARR. Glycated hemoglobin decreased significantly (∆ = −0.52 units) after treatment. Both the test groups showed longer-lasting improvements of periodontal parameters. In diabetic patients, periodontal treatment was effective at reducing plasma ROM, which is an indicator of systemic oxidative stress and inflammation. The treatment of periodontal infection might facilitate glycemic control and decrease systemic inflammation.
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Rahbar, Mahdi, Amirreza Babaloo, Zohre Babaloo, Shima Ghasemi, and Amjad Amini. "Evaluation of Clinical Periodontal Indices and Serum Interleukin-27 by One-stage Full-mouth Disinfection and Quadrant Scaling and Root Planing in Periodontitis." Journal of Contemporary Dental Practice 19, no. 8 (2018): 997–1004. http://dx.doi.org/10.5005/jp-journals-10024-2372.

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