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Journal articles on the topic 'Full-thickness macular hole. 25-gauge vitrectomy'

Author: Grafiati

Published: 3 August 2021

Last updated: 29 July 2025

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1

Kaur, Jasmeet, Krishnendu Nandi, Rupak Kanti Biswas, and Sourav Sinha. "Bilateral idiopathic macular hole in a young female." BMJ Case Reports 18, no. 5 (2025): e265350. https://doi.org/10.1136/bcr-2025-265350.

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Full thickness macular hole (FTMH) is common in the adult population but rare in young individuals. FTMH in young patients are generally unilateral and often associated with trauma or high myopia. Here, we report the first documented case of bilateral idiopathic full thickness macular hole in a young female in her early 30s who underwent 25-gauge transconjunctival pars plana vitrectomy with brilliant blue-assisted internal limiting membrane peel and C3F8 gas tamponade with subsequent macular hole closure.

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Watanabe, Masahisa, Harumasa Yokota, Hiroshi Aso, et al. "Development of Stage 4 Macular Hole after Spontaneous Closure in a Patient with Stage 2 Macular Hole and a Lamellar Macular Hole-Associated Epiretinal Proliferation." Case Reports in Ophthalmology 12, no. 2 (2021): 481–84. http://dx.doi.org/10.1159/000513132.

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Herein, we report the longitudinal observation of a case with reopening of the macular hole associated with a lamellar macular hole-associated epiretinal proliferation (LHEP) followed by spontaneous closure in patients with stage 2 idiopathic macular hole. A 64-year-old woman was referred for the decreased visual acuity (VA) and acute anorthopia in the right eye. Funduscopy and optical coherence tomography (OCT) showed stage 2 full-thickness macular hole without posterior vitreous detachment (PVD) and operculum formation. Her best-corrected visual acuity (BCVA) was 20/32. One month later, the

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Zhu, Xinlei, Jiaxing Wang, Jianan Li, Haoyu Chen, Bo Huang, and Hua Yan. "The Healing Process and Functional Recovery of Neuroretina after Idiopathic Macular Hole Surgery without Internal Limiting Membrane Reversal Tamponade." Journal of Ophthalmology 2020 (May 5, 2020): 1–7. http://dx.doi.org/10.1155/2020/2478943.

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Purpose. To investigate the healing process and functional recovery of neuroretina after idiopathic macular hole surgery, as well as analyzing the influencing factors. Methods. Thirty-six eyes of 31 patients with full-thickness idiopathic macular hole (IMH) were enrolled in this retrospective study. All of them were operated using 23-gauge or 25-gauge vitrectomy with inner limiting membrane peeling and air tamponade. Spectral-domain optical coherence tomography was performed before surgery and after surgery to observe the structural changes of neuroretina. Results. Twenty eyes (55.56%) had the

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Stec, Maria, Mikołaj Kuźniak, and Sebastian Sirek. "Closure of Full-thickness Macular Hole after Pars Plana Vitrectomy (23G) with Cataract Phacoemulsification, Artificial Intraocular Lens Implantation, and Silicone Oil Administration Due to Rhegmatogenous Retinal Detachment in the Right Eye in a 67-year-old Patient – a Case Report." Ophthalmology 27, no. 1 (2024): 36–38. http://dx.doi.org/10.5114/oku/187932.

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Macular holes pose a significant threat to central vision, necessitating precise diagnosis and intervention with an occurrence of 1 per 1000 patients over the age of 55. This manuscript presents a case study of a 66-year-old man with a retinal detachment in the right eye and full-wall macular hole. The patient underwent a multi-step surgical intervention involving pars plana vitrectomy, internal limiting membrane peeling with silicone oil tamponade, retinal endophotocoagulation, and administration and removal of the perfluorocarbon liquid DK-line in the first step. The second stage of treatmen

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Hashimoto, Yuto, Yusuke Arai, Shinji Makino, Yuji Inoue, Hidenori Takahashi, and Hidetoshi Kawashima. "Full-Thickness Macular Hole with Coats Disease: A Case Report." Case Reports in Ophthalmology 11, no. 2 (2020): 342–47. http://dx.doi.org/10.1159/000508821.

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We report a case of full-thickness macular hole (FTMH) which developed during follow-up for Coats disease. To our knowledge, this is the first report on a case of FTMH which developed during follow-up for Coats disease. A 17-year-old boy was referred to our institution with blurred vision in his left eye. Fundus examination showed yellowish subretinal exudates with overlying telangiectatic retinal vessels in the temporal periphery in the left eye; the right eye was normal. Fluorescein angiography revealed diffusion indicative of temporal peripheral vascular leakage. We made a diagnosis of stag

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Caretti, Luigi, Giulia Pillon, Giacomo Verzola, Cristina Monterosso, and Martina Formisano. "A Prospective Randomized Study Comparing 27-Gauge Vitrectomy to 23-Gauge Vitrectomy for Epiretinal Membranes and Full-Thickness Macular Holes." Journal of Current Ophthalmology 35, no. 3 (2023): 259–66. http://dx.doi.org/10.4103/joco.joco_318_22.

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Purpose: To compare the surgical and clinical outcomes of 27-gauge vitrectomy and 23-gauge vitrectomy. Methods: We conducted a single-center, prospective, randomized study. Fifty-three patients affected by vitreoretinal interface disorders (epiretinal membranes and macular holes) were randomly scheduled to undergo 27-gauge (28 patients) or 23-gauge (25 patients) pars plana vitrectomy. The presence of any potential factor of increased baseline inflammation or eye anatomy influencing the surgery was criteria for exclusion. The time of surgery, postoperative intraocular pressure (IOP), state of s

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Shrestha, Chunu, Sabina Shrestha, Aparajita Manoranjan, and Reeta Rajbhandari. "A 27 - Gauge Microincision Vitrectomy Surgery for Posterior Segment Diseases in a Tertiary Centre, Nepal." Medical Journal of Shree Birendra Hospital 20, no. 2 (2021): 91–96. http://dx.doi.org/10.3126/mjsbh.v20i2.30726.

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Introduction: Transconjunctival micro incision vitrectomy surgery (MIVS) with 23 or 25 gauge instrumentation is more advantageous than traditional 20 gauge surgery. We intended to evaluate the visual outcome, complications and indication of various vitreoretinal diseases using 27 Gauge vitrectomy systems.  Methods: This study was a prospective, interventional, non-comparative study conducted in Nepal Eye Hospital from June 2017 to July 2018. Fifty-two patients with various vitreoretinal diseases were recruited. The main outcome measures included corrected distance visual acuity (CDVA) pr

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Hagenau, Felix, Elisa V. Osterode, Julian E. Klaas, et al. "Long-Term Results of Adjunct Autologous Platelet-Rich Plasma in Lamellar Macular Hole Surgery Showing Lasting Restoration of Foveal Anatomy." International Journal of Molecular Sciences 24, no. 5 (2023): 4589. http://dx.doi.org/10.3390/ijms24054589.

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The aim of this study was to evaluate the long-time results of highly concentrated autologous platelet-rich plasma (PRP) used as an adjunct in lamellar macular hole (LMH) surgery. Nineteen eyes of nineteen patients with progressive LMH were enrolled in this interventional case series, on which 23/25-gauge pars plana vitrectomy was performed and 0.1 mL of highly concentrated autologous platelet-rich plasma was applied under air tamponade. Posterior vitreous detachment was induced, and the peeling of tractive epiretinal membranes, whenever present, was performed. In cases of phakic lens status,

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Giansanti, Fabrizio, Cristina Nicolosi, Dario Giorgio, et al. "Myopic Macular Hole and Detachment after Gene Therapy in Atypical RPE65 Retinal Dystrophy: A Case Report." Genes 15, no. 7 (2024): 879. http://dx.doi.org/10.3390/genes15070879.

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Purpose: To report a case of macular hole and detachment occurring after the subretinal injection of Voretigene Neparvovec (VN) in a patient affected by atypical RPE65 retinal dystrophy with high myopia and its successful surgical management. Case description: We report a case of a 70-year-old man treated with VN in both eyes. The best corrected visual acuity (BCVA) was 0.7 LogMar in the right eye (RE) and 0.92 LogMar in the left eye (LE). Axial length was 29.60 mm in the RE and 30.28 mm in the LE. Both eyes were pseudophakic. In both eyes, fundus examination revealed high myopia, posterior st

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Shilov, N. M., A. V. Tereshchenko, M. A. Plakhotnii, N. N. Yudina, S. V. Novikov, and S. Zh Kabuldinova. "The first use of an internal limiting membrane fragment and platelet- rich plasma in surgery for a full thickness macular hole without vitreous tamponade (preliminary results)." Russian Journal of Clinical Ophthalmology 25, Special Issue (2025): 82–89. https://doi.org/10.32364/2311-7729-2025-25-suppl-12.

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Aim: to develop a new marginally traumatic surgical technique using a combination of an inverted fragment of the internal limiting membrane (ILM) and platelet rich plasma (PRP) without vitreous tamponade to manage primary full thickness macular retinal ruptures, as well as to study its anatomical and functional effectiveness. Materials and Methods: 23 subjects (23 eyes) aged from 53 to 73 years with primary macular holes (MH) (minimum diameter: 152 — 623 μm) were under medical supervision. The surgical technique performed in the study group included subtotal vitrectomy, formation of an inverti

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Abrishami, Mojtaba, Mehrdad Motamed Shariati, Ali Bolouki, and Ghodsieh Zamani. "Gas Expansion Three Days after Pars Plana Vitrectomy with Sulfur Hexafluoride 20% Tamponade following Carbon Monoxide Toxicity and Oxygen Therapy." Case Reports in Ophthalmological Medicine 2022 (May 9, 2022): 1–3. http://dx.doi.org/10.1155/2022/5035361.

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Purpose. To report an unusual case of gas expansion following oxygen therapy in a patient with sulfur hexafluoride (SF6) 20% tamponade after pars plana vitrectomy. Case Report. A 40-year-old man came to the clinic with severe ocular pain and redness and also vision decrease in his left eye three days after uncomplicated 23-gauge pars plana vitrectomy, internal limiting membrane peeling combined with phacoemulsification, and using 20% SF6 injection as a tamponade agent due to significant cataract and a full-thickness macular hole. In ophthalmic examinations of his left eye, high intraocular pre

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Hejsek, Libor, Alexandr Stepanov, Jaroslava Dusova, et al. "Microincision 25G Pars Plana Vitrectomy with Peeling of the Inner Limiting Membrane and Air Tamponade in Idiopathic Macular Hole." European Journal of Ophthalmology 27, no. 1 (2016): 93–97. http://dx.doi.org/10.5301/ejo.5000815.

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Purpose To evaluate the success of a mini-invasive technique for operation of idiopathic macular hole (IMH). Methods We retrospectively examined 29 patients (30 eyes) in whom 25-G pars plana vitrectomy (PPV), peeling of the inner limiting membrane (ILM), and application of air tamponade were performed. The group of the patients included 7 males and 22 females (76%), age range 57-79 years (median 70). The follow-up period was 3-47 months (median 17). Results Pars plana vitrectomy was indicated only in the stages of full-thickness macular hole. Prior to operation, 13 eyes (43%) were in stage 2,

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Banker, Alay S., Bansri M. Mahadevia, Harita Shah, and Ahan A. Banker. "Full Thickness Macular Hole in Aesthetician Occurring Due to Accidental Self-exposure to Cosmetic Laser Machine Trying to Take Special Precautions Against COVID-19." Journal of Cutaneous and Aesthetic Surgery 17, no. 1 (2024): 75–77. http://dx.doi.org/10.4103/jcas.jcas_74_21.

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Abstract A 25-year-old aesthetician was operating Q-switch pulse (SPECTRA) cosmetic laser machine of 1,064 nm wavelength, for the purpose of skin bleaching. The probe suddenly slipped over the plastic sheet that had been placed to avoid COVID-19 exposure after which she complained of sudden loss of vision. She was diagnosed as having vitreous hemorrhage in her right eye and was treated conservatively for one month. She then complained of central scotoma and was diagnosed to have developed a full-thickness macular hole, for which she was advised vitrectomy surgery. The purpose of this case repo

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D’Aloisio, Rossella, Paolo Carpineto, Agbéanda Aharrh-Gnama, et al. "Early Vascular and Functional Changes after Vitreoretinal Surgery: A Comparison between the Macular Hole and Epiretinal Membrane." Diagnostics 11, no. 6 (2021): 1031. http://dx.doi.org/10.3390/diagnostics11061031.

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(1) Background: The aim of this observational comparative study was to investigate early retinal vascular and functional changes in patients undergoing vitreoretinal surgery for idiopathic epiretinal membrane (iERM) or macular hole (MH) using a widefield swept-source optical coherence tomography angiography (WSS-OCTA). (2) Methods: Forty one diseased eyes were enrolled in the study. Twenty three eyes with iERM diagnosis (ERM group) underwent 25-gauge vitrectomy with inner limiting membrane (ILM) and MER peeling, while eighteen eyes with MH (MH group) underwent 25-gauge vitrectomy with inverted

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Muhammad Amer Awan, Fiza Shaheen, and Kholood Janjua. "Outcomes of 27 gauge pars plana vitrectomy for a variety of posterior segment diseases." Journal of the Pakistan Medical Association 71, no. 11 (2021): 2570–75. http://dx.doi.org/10.47391/jpma.12262.

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Objective: To report our experience with 27 gauge (27G) pars plana vitrectomy (PPV) system for a variety of simple to complex posterior segment disorders Methods: Single center, Retrospective, Cohort study. Data of 665 eyes of 574 patients that underwent 27G PPV for a variety of indications from July 2015 to June 2019 at a tertiary care hospital was analyzed. Results: Common surgical indications included; Diabetic tractional retinal detachment (196, 29.5%), vitreous haemorrhage (191, 28.7%), full thickness macular hole (80, 12%), epiretinal membrane (66, 9.9%), endophthalmitis (26, 3.9%), trac

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Sato, Mariko, and Takeshi Iwase. "Swept Source-Optical Coherence Tomography-Guided Facedown Posturing to Minimize Treatment Burden and Maximize Outcome after Macular Hole Surgery." Journal of Clinical Medicine 12, no. 16 (2023): 5282. http://dx.doi.org/10.3390/jcm12165282.

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We evaluated the closure of full-thickness macular holes (MHs) the day after surgery in minimizing the burden and maximizing patient outcomes. Herein, 25-gauge pars plana vitrectomy, internal limiting membrane peeling, and fluid–gas (20% sulfur hexafluoride) were performed for the treatment. Patients were instructed to remain in the facedown position until the confirmation of MH closure, and the position was discontinued in cases where the closure was confirmed. In total, 43 eyes of 43 patients, whose average age was 69.7 ± 8.6 years, were enrolled in this study. We used swept source (SS)-opti

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Harasawa, Mariana, Hugo Quiroz-Mercado, Guillermo Salcedo-Villanueva, Gerardo Garcia-Aguirre, and Shulamit Schwartz. "Inner Segment Ellipsoid Band and Cone Outer Segment Tips Changes Preceding Macular Hole Development in a Young Patient." Case Reports in Ophthalmological Medicine 2014 (2014): 1–3. http://dx.doi.org/10.1155/2014/132565.

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Purpose. Pathophysiology of macular hole (MH) is not yet well defined but the advances of spectral domain optical coherence tomography (SD-OCT) give us access to further detailed imaging. We report a case with macular inner segment ellipsoid (ISe) band loss and cone outer segment tips (COST) line changes seen in SD-OCT preceding MH appearance in a young patient.Methods. 21-year-old woman presented with a partial central scotoma, metamorphopsia, and a 20/25 vision in her right eye. Past medical history was positive for laser assisted in situ keratomileusis (LASIK) surgery 7 months ago with no c

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Buzzi, Matilde, Guglielmo Parisi, Paola Marolo, et al. "The Short-Term Results of Autologous Platelet-Rich Plasma as an Adjuvant to Re-Intervention in the Treatment of Refractory Full-Thickness Macular Holes." Journal of Clinical Medicine 12, no. 5 (2023): 2050. http://dx.doi.org/10.3390/jcm12052050.

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The purpose of this study was to investigate the short-term efficacy and safety of autologous platelet-rich plasma (a-PRP) as an adjuvant to revisional vitrectomy for refractory full-thickness macular holes (rFTMHs). We conducted a prospective, non-randomized interventional study including patients with rFTMH after a pars plana vitrectomy (PPV) with internal limiting membrane peeling and gas tamponade. We included 28 eyes from 27 patients with rFTMHs: 12 rFTMHs in highly myopic eyes (axial length greater than 26.5 mm or a refractive error greater than -6D or both); 12 large rFTMHs (minimum hol

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Kleymenov, A. Yu, V. N. Kazaykin, and A. V. Lizunov. "Remote functional and anatomical results of idiopathic macular hole surgery performed without postsurgical vitreous cavity tamponade." Russian Ophthalmological Journal 15, no. 2 (2022): 30–36. http://dx.doi.org/10.21516/2072-0076-2022-15-2-30-36.

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Purpose. To assess remote results of our method of macular hole (MH) surgery without postsurgical vitreous cavity tamponade. Material and methods. 34 eyes of34 patients were operated for full-thickness MH 100 to 932 (558.5 ± 50.9) microns in diameter with no vitreous cavity tamponade. Before surgery, best corrected visual acuity (BCVA) was 0.02 to 0.25 (0.11±0.02). The operation included 3-port 25—27 G vitrectomy, separation of posterior hyaloid membrane, staining and removal of the internal limiting membrane (ILM) with subsequent exchange of salt solution for air. The hole edges were passive

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Bhatti, Muhammad Tayyab, and Maria Teresa Sandinha. "The impact of surgery on self-reported metamorphopsia and vision-related quality of life in patients with an idiopathic full-thickness macular hole." British Student Doctor Journal 6, no. 1 (2022): 41–49. http://dx.doi.org/10.18573/bsdj.237.

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Background:Metamorphopsia (distorted vision) is among the most common symptoms reported by patients with idiopathic full thickness macular hole (iFTMH) and is related to significant deterioration in Vision-Related Quality-of-Life (VRQoL). Surgical closure with pars plana vitrectomy (PPV) is the chief determinant of visual acuity postoperatively, but the extent of visual improvement is variable. The aim of this study was to assess the impact of surgery on the self-reported prevalence and severity of metamorphopsia and the VRQoL in patients with an iFTMH. Methods: Prospective consecutive case se

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Rao, Prethy, Yoshihiro Yonekawa, Benjamin J. Thomas, and Kimberly A. Drenser. "Spectral versus Time-Domain OCT in Detecting Preoperative Epiretinal Membranes that Accompany Macular Holes." European Journal of Ophthalmology 27, no. 2 (2016): 185–89. http://dx.doi.org/10.5301/ejo.5000862.

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Purpose To compare the sensitivities of spectral-domain optical coherence tomography (SD-OCT) versus time-domain OCT (TD-OCT) in identifying epiretinal membranes (ERM) preoperatively in patients who underwent surgery for full-thickness macular holes (FTMH). Methods This is an interventional retrospective case series of 59 eyes diagnosed with FTMHs who underwent 25-G pars plana vitrectomy with internal limiting membrane peeling between 2009 and 2015. Preoperative OCTs were obtained by SD-OCT (Spectralis, Heidelberg, Germany) or TD-OCT (Stratus, Carl Zeiss Meditec, Dublin, CA, USA). Volume scans

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Shah, Rachana Prashant, Zeenal George Dabre, and Sabyasachi Sengupta. "An outbreak of subhyaloid hemorrhage after accidental laser exposure during an Indian festival." Indian Journal of Ophthalmology 72, Suppl 1 (2023): S144—S147. http://dx.doi.org/10.4103/ijo.ijo_499_23.

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Purpose: To report the clinical manifestations and outcomes of patients who experienced retinal damage due to accidental laser exposure during a festival in Kolhapur, Maharashtra. Methods: Consecutive patients who presented with sudden loss of vision following exposure to laser lights during a religious Indian festival (Ganapati festival) on the same day (9 September 2022) at the same location (idol visarjan procession) were identified from the medical records of various eye hospitals in Kolhapur district of Maharashtra. Eyes with persistent subhyaloid hemorrhage (SHH) were taken up for neodym

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Далидович, А. А., and Л. Н. Марченко. "Surgical Treatment of Full-Thickness Macular Holes of Large Size." Офтальмология. Восточная Европа 14, no. 2 (2024): 220–28. http://dx.doi.org/10.34883/pi.2024.14.2.020.

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Введение. Вариабельность размеров, длительности заболевания и остроты зрения при полных макулярных отверстиях (ПМО) влияют на недостаточную предсказуемость результативности лечения пациентов, в частности при ПМО больших параметров. Цель. Анализ анатомических и функциональных результатов закрытия ПМО больших параметров витрэктомией с темпоральным инвертированным лоскутом внутренней пограничной мембраны (ВПМ) для отбора пациентов с потенциальным благоприятным исходом. Материалы и методы. Выполнено проспективное исследование 45 глаз 45 пациентов (9 мужчин, 36 женщин) в возрасте 62,5±5,9 года с ПМ

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Arsyutov, D. G. "A new approach to the treatment of central retinal detachment with a macular hole in patients with extreme myopia and scleral staphyloma." Russian Ophthalmological Journal 16, no. 4 (2023): 7–10. http://dx.doi.org/10.21516/2072-0076-2023-16-4-7-10.

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Purpose. To develop a methodology of surgical treatment of central retinal detachment with macular holes of various diameters in patients with high myopia and scleral staphyloma using autologous conditioned plasma (ACP) as a rupture blocking composite and pneumoretinopexy as the final tamponade, and analyze the results of this treatment.Material and methods. The surgery included subtotal vitrectomy 25+, 27G, peeling of the inner limiting membrane, pneumoretinopexy, introduction of ACP into the area of scleral staphyloma through the macular hole, and, upon the formation of a plasma seal at the

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H Su, Erin, Niranjana Kesavamoorthy, and Hossein Ameri. "Macular hole reopening after inverted internal limiting membrane flap." Journal of Case Reports and Images in Ophthalmology 5, no. 2 (2022): 24–28. http://dx.doi.org/10.5348/100034z17es2022cr.

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Introduction: Here, we present a case of macular hole (MH) reopening after an initial successful closure with an inverted internal limiting membrane (ILM) flap procedure. Case Report: The patient was a 72-year-old Hispanic male who presented with decreased vision in the right eye who was found to have a 431 μm, full-thickness macular hole. The patient underwent three separate 25-gauge pars plana vitrectomies to correct the macular hole. The first involved an inverted ILM flap technique, the second one removal of the flap and the third one subretinal injection of balanced salt solution (BSS). C

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Arsiutov, D. G. "Surgical treatment of central retinal detachment with macular hole in patients with high myopia and scleral staphyloma." Reflection, no. 1 (June 7, 2022): 19–21. http://dx.doi.org/10.25276/2686-6986-2022-1-19-21.

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Purpose. To analyze the results of surgical treatment of central retinal detachment against the background of macular holes of various diameters in patients with high myopia and scleral staphyloma using autologous conditioned plasma (ACP) as a hole blocking composite and pneumoretinopexy as the final tamponade. Methods. Surgical tactics included subtotal vitrectomy 25 +, 27G, peeling of the inner limiting membrane, pneumoretinopexy, introduction of ACP into the area of scleral staphyloma through the macular hole, and, after the formation of a plasma seal at the base, application of ACP to the

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Arsiutov, D. G. "Tactics of surgical treatment of central retinal detachment with macular hole of different diameter in patients with high myopia and scleral staphyloma." Modern technologies in ophtalmology, no. 1 (March 25, 2022): 12–14. http://dx.doi.org/10.25276/2312-4911-2022-1-12-14.

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Purpose. The aim of the work was to analyze the results of surgical treatment of patients with central retinal detachment against the background of macular holes of various diameters in patients with high myopia and scleral staphyloma using autologous conditioned plasma (ACP) as a hole blocking composite and pneumoretinopexy as the final tamponade. Material and methods. Surgical tactics included subtotal vitrectomy 25+, 27G, peeling of the inner limiting membrane, pneumoretinopexy, introduction of ACP into the area of the scleral staphyloma through the macular hole, and after the formation of

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Arsiutov, D. G. "Tactics of surgical treatment of central retinal detachment with macular hole of different diameter in patients with high myopia and scleral staphyloma." Modern technologies in ophtalmology, no. 1 (March 25, 2022): 12–14. http://dx.doi.org/10.25276/2312-4911-2022-1-12-14.

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Purpose. The aim of the work was to analyze the results of surgical treatment of patients with central retinal detachment against the background of macular holes of various diameters in patients with high myopia and scleral staphyloma using autologous conditioned plasma (ACP) as a hole blocking composite and pneumoretinopexy as the final tamponade. Material and methods. Surgical tactics included subtotal vitrectomy 25+, 27G, peeling of the inner limiting membrane, pneumoretinopexy, introduction of ACP into the area of the scleral staphyloma through the macular hole, and after the formation of

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He, Shuai, Zhong-Yi Zhou, Xiao-Meng Li, Wu Xu, and Qing-Hua Qiu. "A novel surgical technique of internal limiting membrane peeling for high myopic foveoschisis: a wide range of whole piece consecutive peeling without preservation of epi-fovea." International Journal of Ophthalmology 15, no. 2 (2022): 284–90. http://dx.doi.org/10.18240/ijo.2022.02.14.

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AIM: To demonstrate an improved surgical technique of whole piece consecutive internal limiting membrane (ILM) peeling without preservation of the epi-fovea to treat high myopic foveoschisis (MF). METHODS: A 23-gauge 3-port pars plana vitrectomy was performed on 16 patients with high MF. A parallel arc line along the vascular arcades was scraped out with a curved membrane scraper DSP. Next, an ILM forceps was used to catch hold of the incisal edge of the ILM flap, and the action of releasing and separating was subsequently taken toward the direction of the macular fovea. Next, the ILM forceps

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Arsiutov, D. G., and N. P. Pashtaev. "Modern technology of surgical treatment for central retinal detachment with macular hole in patients with highly complicated myopia and scleral staphyloma." EYE GLAZ 25, no. 2 (2023): 108–14. http://dx.doi.org/10.33791/2222-4408-2023-2-108-114.

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Introduction. At present the major problem is the imperfection of the surgical approaches and the effectiveness of the surgical treatment for macular holes of various diameters associated with central retinal detachment in patients with high myopia and scleral staphyloma in the central zone. The main difficulty lies in creating the effective tamponade of the vitreous cavity necessary to close the macular hole. No less important is the effective blocking of the macular hole itself in the presence of deep scleral staphyloma. Silicone oils are currently used as a tamponing agent in most cases. Th

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Cunningham, Matthew, Elias Mavrofrides, Luke Mavrofrides, and Emily Schofield. "Surgical and visual outcomes of small-gauge pars plana vitrectomy for full-thickness macular hole associated with type 2 idiopathic macular telangiectasia." Medical Research Archives 12, no. 12 (2024). https://doi.org/10.18103/mra.v12i12.6187.

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Objective: To examine the clinical features and outcomes of pars plana vitrectomy for full-thickness macular hole (MH) in patients with type 2 macular telangiectasia (MacTel). Methods: Retrospective, interventional case series of consecutive patients with MacTel type 2 who underwent surgical repair of full thickness macular holes from January 2015 to January 2021 at a busy vitreoretinal surgery practice. The rate of macular hole closure, and visual outcome following repair were evaluated. Results: Eight eyes of MacTel patients with full thickness macular holes were identified; however, 4 of th

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Al Karam, Muntadher, Rike Michels, and Stephan Michels. "DELAYED ONSET OF SPONTANEOUS LARGE FULL THICKNESS MACULAR HOLE CLOSURE." RETINAL Cases & Brief Reports, March 31, 2025. https://doi.org/10.1097/icb.0000000000001750.

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Purpose: Reporting this rare case of spontaneous delayed-onset full-thickness macular hole (ftMH) closure after unsuccessful initial surgical treatment encourages to have new perspectives on the mechanism behind this retinal process. Methods: Uneventful 27-gauge vitrectomy was performed in a 71-year-old female patient for large (460 µm) macular hole (MH). The surgery was combined with peeling of the ILM, SF6 tamponade and head down positioning for 3 days. No closure of the MH was detected within 4 weeks after surgery and visual acuity remained unchanged. The patient refused a re-vitrectomy. Re

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Bertolani, Yann, Albert Arnaiz-Camacho, Jorge Fernández-Engroba, Jose García-Arumí, and Miguel-Ángel Zapata. "Successful use of PRGF-endoret® and ILM peeling for full thickness macular hole in MacTel type 2: A case report and review of literature." European Journal of Ophthalmology, November 26, 2024. http://dx.doi.org/10.1177/11206721241301933.

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Purpose To describe the successful use of plasma rich in growth factors (PRGF-Endoret®) and internal limiting membrane peeling for full thickness macular hole in Macular Telangiectasia type 2. Case presentation A case report of a full thickness macular hole (FTMH) associated with Macular Telangiectasia (MacTel) type 2 is described. 25-G vitrectomy with internal limiting membrane (ILM) peeling and use of (PRGF-Endoret®) was performed. Several ophthalmological visits were conducted and multiple diagnostic tests were carried out including optical coherence tomography (OCT) and fluorescein angiogr

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Roubelat, François-Philippe, Vincent Gualino, Pierre R. Fournié, and Vincent J. Soler. "Amniotic membrane grafting for a case of bilateral giant full-thickness macular hole in Alport syndrome after cataract surgery." RETINAL Cases & Brief Reports, October 9, 2023. http://dx.doi.org/10.1097/icb.0000000000001428.

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Abstract Purpose: To describe the surgical management of bilateral giant full-thickness macular hole with sudden onset two months after cataract surgery in a patient with Alport syndrome. Methods: Observational, single-case report. Results: A 54-year-old female with a history of Alport syndrome presented with severe bilateral visual loss two months after cataract surgery. The diagnosis of bilateral giant full-thickness macular hole was made. We found the absence of the internal limiting membrane and the inability to lift and peel a continuous posterior hyaloid sheet during surgical management

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Yagura, Tatsuya, Kentaro Nishida, Sakaguchi Hirokazu, and Kohji Nishida. "A Case of Closure of Recurrent Full-Thickness Macular Hole by Spontaneous Retinal Detachment around the Macular Hole and Gas Tamponade." Case Reports in Ophthalmology, February 14, 2024, 150–56. http://dx.doi.org/10.1159/000536338.

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<b><i>Introduction:</i></b> Here, we present a case of full-thickness macular hole (FTMH) recurrence following two vitrectomies, accompanied by additional internal limiting membrane (ILM) peeling and gas tamponade. Ultimately, FTMH closure was accomplished by spontaneous retinal detachment around the macular hole and gas tamponade alone. <b><i>Case Presentation:</i></b> The patient, a 54-year-old woman with a lamellar macular hole, had a visual acuity of 20/100 in her left eye. The treatment regimen included cataract surgery, a 25-gauge pars plan

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Kannan, Naresh Babu, Muthukrishnan Vallinayagam, Ananya Goswami, and Reshma Dara. "Macular hole associated Retinal Detachment in presumed Autosomal Recessive Bestrophinopathy (ARB)– A retrospective observational series of two cases." RETINAL Cases & Brief Reports, October 2, 2024. http://dx.doi.org/10.1097/icb.0000000000001661.

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Purpose: Surgical outcome of presumed Autosomal Recessive Bestrophinopathy (ARB)with full thickness macular hole and retinal detachment managed by pars plana vitrectomy. Methods: A retrospective observational case series of two eyes of two patients who underwent 25 G pars plana vitrectomy with peeling of internal limiting membrane and SF6 tamponade and were assessed with respect to best corrected visual acuity, fundus photographs and spectral domain optical coherence tomography. Results: Type 1 closure of macular hole was achieved along with resolution of retinal detachment in both patients. C

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Pellegrini, Marco, Ginevra Adamo, Chiara Vivarelli, et al. "Macular Hole Surgery and Retinal Tectonics: The Impact of Internal Limiting Membrane Peeling Size on Tangential Retinal Displacement." Retina, September 25, 2024. http://dx.doi.org/10.1097/iae.0000000000004276.

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Purpose: The aim of the study was to evaluate the tangential retinal displacement occurring following macular hole surgery, and to assess the impact of the internal limiting membrane (ILM) peeling size on the extent of the retinal movement. Methods: This retrospective study included patients with full-thickness macular hole undergoing 25-gauge pars plana vitrectomy with ILM peeling. Patients received either a small ILM peeling with a size of 2-disc diameters or a large peeling extended up to the vascular arcades. Near-infrared retinal imaging was performed with the Spectralis (Heidelberg Engin

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Benzerroug, Mounir, Maude Marchand, Solène Coisy, Bénédicte Briend, Bertrand Boussion, and Chérif Mazit. "25-gauge versus 27-gauge Vitrectomy for Management of Vitreoretinal Diseases: A Large Prospective Randomized Trial." Retina, January 18, 2024. http://dx.doi.org/10.1097/iae.0000000000004048.

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Purpose: To compare the safety and performance clinical outcomes of the 27-gauge (G) two-dimensional cutting vitrectomy probe versus a standard 25-G probe for retinal procedures. Methods: In this large randomized prospective study, all candidates for epiretinal membrane or macular hole surgery were randomized to the 27-G group or 25-G group. Outcome measures included surgery time, changes in best-corrected distance visual acuity (BCDVA), intraocular pressure (IOP), central macular thickness (CMT) between baseline and 1- and 3-months follow-up timepoints. Moreover, intraoperative and postoperat

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Valmaggia, Christophe, Filip Kostadinov, Corina Lang, and Josef Guber. "Comparative study of combined vitrectomy with phacoemulsification versus vitrectomy alone for primary full-thickness macular hole repair." BMC Ophthalmology 21, no. 1 (2021). http://dx.doi.org/10.1186/s12886-021-01918-2.

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Abstract Background To assess the effectiveness and safety of 23-gauge pars plana vitrectomy combined with phacoemulsification versus vitrectomy alone in patients over 50 years with primary full-thickness macular holes (FTMH). Methods We retrospectively reviewed the medical records related to 406 consecutive vitrectomies performed for primary FTMH. Phacovitrectomy was performed in 294 phakic eyes whereas vitrectomy alone in 112 pseudophakic eyes. The cases were divided into three groups according to the stage of the FTMH: stage 2 (n = 93), stage 3 (n = 270), or stage 4 (n = 43). The primary ou

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Figueroa, Marta S., Susana Noval, and Inés Contreras. "Macular structure on optical coherence tomography after lamellar macular hole surgery and its correlation with visual outcome." December 7, 2011. https://doi.org/10.1016/j.jcjo.2011.09.011.

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Abstract <strong> Objective: </strong> To report macular structure on optical coherence tomography (OCT) after lamellar macular hole surgery and its relationship with visual outcome. <strong> Design: </strong> Retrospective interventional case series; private practice setting. <strong> Participants: </strong> Twelve patients diagnosed with a lamellar hole who had undergone vitrectomy and who had OCT scanning before and after surgery and at least 6 months follow-up were included. <strong> Methods: </strong> Surgery consisted of 25 g vitrectomy, peeling of epiretinal and internal limiting membra

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Feo, Alessandro, Enrico Giacomotti, Francesco Santoru, et al. "PUNCTATE INNER CHOROIDOPATHY FOLLOWING PARS PLANA VITRECTOMY FOR HIGH MYOPIC FULL THICKNESS MACULAR HOLE." RETINAL Cases & Brief Reports, July 19, 2024. http://dx.doi.org/10.1097/icb.0000000000001641.

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Purpose: To describe a case of punctate inner choroidopathy (PIC) and secondary or epiphenomenon multiple evanescent white dot syndrome (EpiMEWDS) following surgery for high myopic full-thickness macular hole (FTMH). Methods: Case report. Results: A 57-year-old high myopic female was diagnosed with cataract and FTMH in the left eye. Her initial best-corrected visual acuity (BCVA) was 20/20 in her right eye and 20/80 in the left eye. She underwent routine combined phacoemulsification and 25-gauge pars plana vitrectomy (PPV) with the inverted internal limiting membrane (ILM) technique and twice-

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Arshad, Muhammad Owais, Syed Fawad Rizvi, Saliha Naz, Syed Ali Afsar, Hunain Razzak Ghoghari, and Muhammad Tanweer Hassan Khan. "<b>TO</b><b> </b><b>DETERMINE</b><b> </b><b>THE</b><b> </b><b>CHANGE</b><b> </b><b>IN</b><b> </b><b>THE</b><b> </b><b>SIZE</b><b> </b><b>OF</b><b> </b><b>MACULAR</b><b> </b><b>HOLE DURING SURGERY BEFORE AND AFTER THE INTERNAL LIMITING MEMBRANE PEELING USING INTRAOPERATIVE OPTICAL COHERENCE TOMOGRAPHY</b>." Journal of Medical & Health Sciences Review 2, no. 3 (2025). https://doi.org/10.62019/cs4mpr41.

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Background: Macular hole (MH) surgery has evolved significantly with the advent of intraoperative optical coherence tomography (iOCT), which allows real-time visualization of retinal architecture during key surgical steps such as internal limiting membrane (ILM) peeling. Objective: To determine the change in the size of macular hole diameter before and after ILM peeling using intraoperative OCT during macular hole surgery. Methodology: This prospective interventional study was conducted at LRBT, Tertiary Care Eye Hospital, Karachi, for six months, i.e, from 1st January 2023 to 30th June 2023,

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El Rayes, Ehab N., Mahmoud Leila, and Panagiotis Stavrakas. "Multi-layer internal limiting membrane plug technique for management of large full-thickness macular holes." International Journal of Retina and Vitreous 8, no. 1 (2022). http://dx.doi.org/10.1186/s40942-022-00428-7.

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Abstract Background To evaluate the efficacy of the multi-layer internal limiting membrane plug (MIP) technique in promoting the closure of large full-thickness macular holes (FTMH) and improvement of visual function. Methods A prospective interventional non-comparative consecutive case series including patients with surgically naïve large FTMH whether primary or secondary. All macular holes were > 400 µm. All patients had 23-gauge pars plana vitrectomy (PPV), MIP technique, and sulfur hexafluoride (SF6) 20% gas tamponade. The main outcome measures were the closure of the hole, improvement

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Schöneberger, Verena, Rahul Jonas, Leonie Menghesha, et al. "Secondary full thickness macular holes following vitrectomy for rhegmatogenous retinal detachment: Clinical data, surgical outcome and prognosis." Acta Ophthalmologica 102, S279 (2024). http://dx.doi.org/10.1111/aos.15892.

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Aims/Purpose: Formation of a full‐thickness macular hole (MH) after vitrectomy is extremely rare. Previous studies only included small numbers of cases. Aim of the present study was to describe course, functional prognosis and risk factors of secondary macular hole development following surgical treatment of a primary rhegmatogenous retinal detachment (RRD) in a large data set from two tertiary eye clinics.Methods: Formation of a full‐thickness macular hole (MH) after vitrectomy is extremely rare. Previous studies only included small numbers of cases. Aim of the present study was to describe c

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Franceschi, Alessandro, and Nicola Zemella. "No optic pit macular retinoschisis associated with macular hole and chorioretinal scars: A case report." European Journal of Ophthalmology, May 27, 2025. https://doi.org/10.1177/11206721251345015.

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Purpose To describe a unique case of no optic pit retinoschisis (NOPIR) associated with a tractional full-thickness macular hole (FTMH) in a patient with a presumed history of ocular toxoplasmosis. Case report A 65-year-old non-myopic Caucasian male with a presumed history of ocular toxoplasmosis reported sudden visual acuity decrease in his right eye (RE). His best-corrected visual acuity (BCVA) was 20/2000 in the RE. A fundus examination and optical coherence tomography (OCT) revealed a full-thickness macular hole (FTMH) associated with a macular epiretinal membrane, which originated from tw

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Rojas-Juárez, Sergio, Javier Cisneros-Cortés, Abel Ramirez-Estudillo, and Raul Velez-Montoya. "Autologous full-thickness retinal transplant for refractory large macular holes." International Journal of Retina and Vitreous 6, no. 1 (2020). http://dx.doi.org/10.1186/s40942-020-00266-5.

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Abstract Background Despite the constant refinement of techniques and surgical aids, extremely large and refractory macular holes continue to have poor surgical outcomes with the current standard of care. The objective of the present study is to assess the anatomical and functional outcomes, as well as the structural change through time, of the optical coherence tomography of patients with refractory macular holes treated with a full-thickness autologous retinal transplant. Methods Prospective, case series. We include patients with a clinical diagnosis of refractory macular holes with a minimu

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Dera, Adrianna U., Doerte Stoll, Verena Schoeneberger, et al. "Anatomical and functional results after vitrectomy with conventional ILM peeling versus inverted ILM flap technique in large full-thickness macular holes." International Journal of Retina and Vitreous 9, no. 1 (2023). http://dx.doi.org/10.1186/s40942-023-00509-1.

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Abstract Background Aim of the study was to compare success rate and functional outcome following pars plana vitrectomy (PPV) with conventional internal limiting membrane (ILM) peeling versus ILM flap technique for full-thickness idiopathic macular holes (FTMH). Methods Retrospective analysis of consecutive eyes with FTMH having undergone vitrectomy with sulfur hexafluoride (SF6) endotamponade 25% at the University Medical Center Rostock, Germany (2009–2020). Eyes were divided according to applied surgical technique (ILM peeling [group P] versus ILM flap [group F]). Inclusion criteria were mac

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Brown, Gordon T., Sangeethabalasri Pugazhendhi, Robert M. Beardsley, John W. Karth, Peter A. Karth, and Allan A. Hunter. "25 vs. 27-gauge micro-incision vitrectomy surgery for visually significant macular membranes and full-thickness macular holes: a retrospective study." International Journal of Retina and Vitreous 6, no. 1 (2020). http://dx.doi.org/10.1186/s40942-020-00259-4.

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Abstract Background To evaluate visual and safety outcomes for 25-gauge (25G) and 27-gauge (27G) micro-incision vitrectomy platforms (MIVS) for the treatment of epiretinal membrane and full-thickness macular holes. Methods Retrospective analysis of all patients who underwent internal limiting membrane (ILM) peel surgery from January 2017 through December 2018. 207 cases met the eligibility criteria for inclusion. Primary endpoint was post-operative Best-Corrected Distance Visual Acuity (BCVA) at 6 months. Results For all patients combined, mean logMAR BCVA improved from 0.57 (± 0.40) to 0.37 (

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Feroz, Lubna, Syed Fawad Rizvi, Saliha Naz, and Tanweer Hassan Khan. "Pre-operative predicting factor in visual outcome after macular hole surgery." Pakistan Journal of Medical Sciences 36, no. 5 (2020). http://dx.doi.org/10.12669/pjms.36.5.1995.

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Objective: To determine the effectiveness of macular hole index (MHI) as a predicting factor of visual outcome after full thickness macular hole surgery. Methods: This quasi-experimental study was conducted at LRBT Free Base Eye Hospital, Karachi from January 2018 to March 2019. Total 45 eyes of 45 patients with full thickness macular hole (FTMH) underwent preoperative Best Corrected Visual Acuity (BCVA) assessment with logMar chart and Optical Coherence Tomography (OCT) scanning, with measurement of base diameter and macular hole height. Values were calculated for the macular hole index

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Huelsbeck, Alyssa C., Colin P. Froines, and Kathleen R. Schildroth. "Sclerochoroidal Calcification Presenting with Unilateral Full-Thickness Macular Hole: Presentation and Successful Surgical Closure." RETINAL Cases & Brief Reports, June 23, 2025. https://doi.org/10.1097/icb.0000000000001784.

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Purpose: Describe a case of macular hole (MH) presenting in a patient with sclerochoroidal calcification (SCC). Only one previous case of a MH in the setting of SCC has previously been reported; however, that case was observed without surgery. We present a case of a MH in SCC in which successful surgical closure and visual acuity improvement was achieved. Methods: Case report Results: A 70-year-old male presented for retinal evaluation of metamorphopsia with a visual acuity of 20/25 in the right eye and 20/300 in the left eye. Fundoscopic examination showed bilateral SCC. Ultrasonographic B-sc

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