Relevant bibliographies by topics / Functional Drug Use

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Functional Drug Use'

Author: Grafiati
Published: 4 June 2021
Last updated: 9 February 2022

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Journal articles on the topic "Functional Drug Use"

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Askew, Rebecca. "Functional fun: Legitimising adult recreational drug use." International Journal of Drug Policy 36 (October 2016): 112–19. http://dx.doi.org/10.1016/j.drugpo.2016.04.018.

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Bunton, David. "The Use of Functional Human Tissues in Drug Development." Alternatives to Laboratory Animals 38, no. 1_suppl (2010): 27–30. http://dx.doi.org/10.1177/026119291003801s05.

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Rydberg, Patrik, Flemming Steen Jørgensen, and Lars Olsen. "Use of density functional theory in drug metabolism studies." Expert Opinion on Drug Metabolism & Toxicology 10, no. 2 (2013): 215–27. http://dx.doi.org/10.1517/17425255.2014.864278.

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Bunton, David. "The use of functional human tissues in drug development." Cell and Tissue Banking 12, no. 1 (2010): 31–32. http://dx.doi.org/10.1007/s10561-010-9213-5.

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Cummings, Jeffrey, Kate Zhong, and Dietmar Cordes. "Drug Development in Alzheimer’s Disease—The Role of Default Mode Network Assessment in Phase II." US Endocrinology 13, no. 02 (2017): 67. http://dx.doi.org/10.17925/use.2017.13.02.67.

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Alzheimer’s disease (AD) is rapidly becoming more common as the global population ages. New treatments are needed and new approaches to drug development are warranted. The phase II challenge for AD treatment development programs is how to provide proof-of-concept (POC) of the candidate agent without a large long trial equivalent to phase III. We propose that the available data support measures of the default mode network (DMN) using functional magnetic resonance imaging (fMRI) as demonstrating the effect of treatment on cognitive circuits critical to human cognition. Improved DMN function with
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Emir Diltemiz, Sibel, Maryam Tavafoghi, Natan Roberto de Barros, et al. "Use of artificial cells as drug carriers." Materials Chemistry Frontiers 5, no. 18 (2021): 6672–92. http://dx.doi.org/10.1039/d1qm00717c.

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Clarke, William P., and Kelly A. Berg. "Use of functional assays to detect and quantify functional selectivity." Drug Discovery Today: Technologies 7, no. 1 (2010): e31-e36. http://dx.doi.org/10.1016/j.ddtec.2010.07.001.

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Hiroki, Tomoyuki, Shu Taira, Hikaru Katayanagi, et al. "Functional magnetic nanoparticles for use in a drug delivery system." Journal of Physics: Conference Series 200, no. 12 (2010): 122003. http://dx.doi.org/10.1088/1742-6596/200/12/122003.

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van Veenendaal, Tamar M., Dominique M. IJff, Albert P. Aldenkamp, et al. "Chronic antiepileptic drug use and functional network efficiency: A functional magnetic resonance imaging study." World Journal of Radiology 9, no. 6 (2017): 287. http://dx.doi.org/10.4329/wjr.v9.i6.287.

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Warner, A. "Drug use in the neonate: interrelationships of pharmacokinetics, toxicity, and biochemical maturity." Clinical Chemistry 32, no. 5 (1986): 721–27. http://dx.doi.org/10.1093/clinchem/32.5.721.

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Abstract With advances in technology, increasing numbers of premature and very ill neonates are surviving and being referred for treatment to neonatal intensive-care units. A major feature of the treatment they receive is therapy with drugs. However, because of relatively limited information available in the area of neonatal pharmacokinetics, the few drugs that currently can be monitored directly, and the lack of an effective mechanism for measuring the biochemical and functional maturity of the neonate, especially as it relates to drug clearance, therapy of neonates with drugs is certainly mo
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Dissertations / Theses on the topic "Functional Drug Use"

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Forsgren, Johan. "Functional Ceramics in Biomedical Applications : On the Use of Ceramics for Controlled Drug Release and Targeted Cell Stimulation." Doctoral thesis, Uppsala universitet, Nanoteknologi och funktionella material, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-132377.

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Ceramics are distinguished from metals and polymers by their inorganic nature and lack of metallic properties. They can be highly crystalline to amorphous, and their physical and chemical properties can vary widely. Ceramics can, for instance, be made to resemble the mineral phase in bone and are therefore an excellent substitute for damaged hard tissue. They can also be made porous, surface active, chemically inert, mechanically strong, optically transparent or biologically resorbable, and all these properties are of interest in the development of new materials intended for a wide variety of
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Westerbotn, Margareta. "Drug use among the very old living in ordinary households : aspects on well-being, cognitive and functional ability /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7140-979-9/.

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Malvisi, Lucio. "Functional characterization of cytochrome b₅ reductase and its electron acceptor cytochrome b₅ in Plasmodium falciparum." [Tampa, Fla] : University of South Florida, 2009. http://purl.fcla.edu/usf/dc/et/SFE0003265.

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Leach, Kelly Rebecca. "The Use of Forelimb Asymmetry Functional Tests to Determine Motor Recovery With Various Drug Treatments Following Endothelin-Induced Stroke." Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1344607995.

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Yung, Ming-ho, and 容銘浩. "Mechanistic and functional characterization of bitter melon extract (BME) and its bioactive component, MAP30, in combating ovarian cancer oncogenesis and chemoresistance." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/194613.

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Ovarian carcinoma is one of the most leading causes of cancer death among all gynaecologic malignancies worldwide. Although there are advances in cancer treatment for the last decades, the curative rate of this disease is just modestly improved. Chemoresistance is the major obstacle in clinical management of ovarian cancer nowadays. Thus, it is an urgent need for exploring effective alternative therapeutic strategies for ovarian cancer patients with advanced or recurrent disease. Emerging evidence has suggested that targeting cancer cell metabolism is the most promising molecular therapeutic a
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Latham, Jr G. Eric. "From Within the Abyss: Drug Users in Areas of Rural Poverty." TopSCHOLAR®, 2014. http://digitalcommons.wku.edu/theses/1323.

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This research was completed to deal with many unanswered questions regarding drug use, specifically drug use in areas of rural poverty. Look at any "Faces of Meth" billboard or listen to any corporate-news program and one might assume there is a drug epidemic in rural areas. Without research, this allows the viewer to assume that poverty is the fault of the drug user who happens to live in rural places. This study sought to take a qualitative and ethnographic methodology to "embed" the researcher in this setting to see for himself whether these views were valid or invalid. The questions of fun
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Short, Aaron R. "Hydrogels: Use and Function in Cancer Migration, Infiltration, and Drug Delivery." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1471448320.

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Blair, Catherine. "Young adults in drug treatment : the function of substance use to alleviate anxiety and depression." Thesis, University of Leicester, 2005. http://hdl.handle.net/2381/4617.

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Section 1- Literature review Young adults in drug treatment have predominantly been heroin users, many with mental health problems. (1) Young adulthood is a distinct developmental period. It encompasses transisitons to adulthood that are now more difficult to negotiate than in the past and may be disrupted by dependent heroin use; (2) Mental health problems are common amongst those in drug treatment but few studies report separate young adult results; (3) Models including the use of drugs to regulate uncomfortable mood states are reviewed as possible explanations for the relationship between s
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Juergensen, Linda Tataryn. "Searching for a clean fit, a feminist analysis of the function and meaning of illicit injection drug use for women." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq22753.pdf.

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Zartman, Andrea Leigh. "Influence of executive function on medication adherence in neurologically impaired and non-impaired elderly." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5304/.

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Medication non-compliance has become one of the most prevalent reasons for hospitalization and doctor's visits by the elderly. As the elderly population is more likely to have decreased cognitive abilities, it is suggested that neuropsychological factors, especially executive function, are more influential in medication non-compliance than once thought. This study looked at executive function performance on a traditional battery of neuropsychological tests, self-report of perceived ability to perform executive function tasks, and the newly developed Pillbox Test, a performance based IADL measu
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Books on the topic "Functional Drug Use"

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Lisa, Rapport, ed. Nutraceuticals: A guide for healthcare professionals. 2nd ed. Pharmaceutical Press, 2007.

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Nobel Symposium (76th 1989 Lidingö, Sweden). Cholinergic neurotransmission: Functional and clinical aspects : proceedings of Nobel Symposium 76. Elsevier, 1990.

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Office, General Accounting. Food safety: FDA's use of faster tests to assess the safety of imported foods : report to Congressional requesters. The Office, 2000.

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Office, General Accounting. Food safety: The agricultural use of antibiotics and its implications for human health : report to the honorable Tom Harkin, ranking minority member, Committee on Agriculture, Nutrition, and Forestry, U.S. Senate. The Office, 1999.

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1951-, Huether Gerald, and North Atlantic Treaty Organization. Scientific Affairs Division., eds. Amino acid availability and brain function in health and disease. Springer-Verlag, 1988.

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Kurup, Ravikumar. Hypothalamic digoxin, cerebral dominance and brain function in health and diseases. Nova Science Publishers, Inc., 2003.

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Addiction Research Foundation (Ont.), ed. Youth and drug abuse: A planner's guide to multi-functional treatment. Addiction Research Foundation, 1994.

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1962-, Supuran Claudiu T., and Winum Jean-Yves, eds. Drug design of zinc-enzyme inhibitors: Functional, structural, and disease applications. John Wiley & Sons, 2009.

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Wang, Binghe, Claudiu T. Supuran, Jean-Yves Winum, and Jean-Yves Winum. Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications. Wiley & Sons, Incorporated, John, 2009.

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Botulinum Toxins in Clinical Aesthetic Practice: Functional Anatomy and Injection Techniques. Taylor & Francis Group, 2018.

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Book chapters on the topic "Functional Drug Use"

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Mosser, A. G., D. A. Shepard, and R. R. Rueckert. "Use of drug-resistance mutants to identify functional regions in picornavirus capsid proteins." In Positive-Strand RNA Viruses. Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-9326-6_12.

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Grailer, Jamison, Richard A. Moravec, Zhijie Jey Cheng, et al. "Considerations in Developing Reporter Gene Bioassays for Biologics." In Methods in Pharmacology and Toxicology. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0171-6_9.

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Abstract The establishment of a robust and reproducible functional bioassay that reliably measures drug potency while ascertaining its mode of action is essential in biologic drug development. Here we describe a simple bioluminescent reporter gene bioassay for assessing biologics targeting immune checkpoints without the complexity and variability of more traditional assay systems. This chapter provides an overview of key considerations in reporter gene bioassay design and optimization, as well as development of thaw-and-use cells as an assay reagent for biologic QC lot release.
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Kwon, Sun Hyung, Jagannath Padmanabhan, Dominic Henn, Kellen Chen, and Geoffrey C. Gurtner. "New Drugs for Scar Treatment." In Textbook on Scar Management. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44766-3_52.

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AbstractCutaneous scar formation following injury is an exuberant fibro-proliferative event and causes aesthetic distress associated with functional problems for those afflicted. Traditionally, surgical revision of excessive hypertrophic scars is commonly performed. However, scar recurrence rate is high and surgical treatments are often combined with radiation therapy, corticosteroid injections, or with other noninvasive therapies. Pharmacological intervention of scar-promoting cellular activities has recently gained traction based on the emerging scientific evidence proving efficacy and safety of new therapeutics in preclinical studies. Ideal new drug therapies would be noninvasive, inexpensive, safe-to-use, and effective in prevention of scar formation. Recently, cytokine-based therapies and modulators of mechanotransduction are being evaluated for their anti-fibrotic properties in the reduction and prevention of scarring. Therapeutic potential of evidence-based new scar therapeutics holds promise toward improving the current wound and scar management practice.
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Rich, Kenneth C. "Immunologic Function and AIDS in Drug-exposed Infants." In Drug Use in Pregnancy: Mother and Child. Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4157-1_13.

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Turner, J. Rick, Dilip R. Karnad, and Snehal Kothari. "Cardiovascular Structure, Function, and Pathophysiology." In Cardiovascular Safety in Drug Development and Therapeutic Use. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-40347-2_3.

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Hallinan, Richard. "Sexual Function and Alcohol and Other Drug Use." In Textbook of Addiction Treatment. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-36391-8_85.

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Hallinan, Richard. "Sexual Function and Alcohol and Other Drug Use." In Textbook of Addiction Treatment: International Perspectives. Springer Milan, 2014. http://dx.doi.org/10.1007/978-88-470-5322-9_142.

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Labouvie, E. W. "The Coping Function of Adolescent Alcohol and Drug Use." In Development as Action in Context. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-662-02475-1_12.

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Bendich, Adrianne, and Ronit Zilberboim. "Use of Drugs that Affect Nutrition and Immune Function." In Diet and Human Immune Function. Humana Press, 2004. http://dx.doi.org/10.1007/978-1-59259-652-2_22.

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McIntyre, Neil. "Hepatic Functions in Health and Disease: Implications in Drug Carrier Use." In Targeting of Drugs With Synthetic Systems. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5185-6_7.

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Conference papers on the topic "Functional Drug Use"

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Kushnarev, Vlad, Glenn Leemans, Cedric Van Holsbeke, Dennis Belmans, Jan De Backer, and Jason Suggett. "The use of functional respiratory imaging to investigate the impact of an oscillating positive expiratory pressure device on lung dynamics and drug deposition." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa3885.

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Chakinala, M. M., H. W. Farber, V. V. McLaughlin, et al. "Selexipag Use: Characterization of the First 500 Patients (pts) in SPHERE (SelexiPag: tHe usErs dRug rEgistry) by World Health Organization (WHO) Functional Class (FC)." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2905.

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Thomas, Antony, Jifu Tan, Susan Perry, and Yaling Liu. "Characterization of Nanoparticle Distribution in Microcirculation Through a Microfluidics Device." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53943.

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Various methods of targeted nano drug delivery have been developed in recent years to reduce side effects, toxicity, and lower drug doses [1]. The use of nanoparticles in drug delivery provides advantages in drug targeting, delivery and release along with serving in diagnosis and therapy [2]. Higher percentage of nanoparticle drug is uptaken by the target cells while larger drug particles are easily cleaned off by the human body. Nanoparticles also have large surface to volume ratio, which aids in attachment of many functional groups and thereby enhances targeting.
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Mignot, B., C. Van Holsbeke, J. Paulukat, A. Copans, and N. R. Henig. "Use of Functional Respiratory Imaging (FRI) to Explore Drug Delivery and Lung Deposition of Inhaled Liposomal Cyclosporine A (L-CsA-i) in Patients After Lung Transplantation (LTx)." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7583.

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Kemp, Regina, Kevin Fraser, Kyoko Fujita, Douglas MacFarlane, and Gloria Elliott. "Biocompatible Ionic Liquids: A New Approach for Stabilizing Proteins in Liquid Formulation." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192986.

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The stabilization of proteins is a priority for several important fields, most notably the pharmaceutical industry. Protein-based therapeutic drugs have demonstrated significant efficacy in controlling and curing disease. Unlike traditional small molecule-based drug therapies, a major hurdle in the development of protein drugs is the challenge of maintaining the protein in the folded state throughout processing and also during storage at the end point-of-use. When a protein is taken from its native environment, it is often unstable and unfolds. Because the protein’s 3-dimensional structure is
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Barker, Gregory, Tre Welch, Nandika D’Souza, Alan Nugent, and Robert Eberhart. "Influence of CO2 Blowing Agent on Porous Bioresorbable Stent Structure." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14073.

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Bioresorbable stents with limited functional lifetimes and with drug delivery capabilities are desired. Various methods have been investigated to induce porosity in bioresorbable polymeric stent fibers, thereby to permit increased drug reservoir capacity versus polymer-coated metal stents. We developed microporous surface layers on PLLA fibers to serve as the drug reservoir, but found that impurities, the use of chemicals, and multiple step procedures associated with our, and other published methods limited utility. Thus we investigated theoretically attractive CO 2 blowing methods, in which g
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Anicescu, Maria-Cristina, Cristina-Elena Dinu-Pirvu, Mihaela Violeta Ghica, et al. "Preliminary analysis of emulsion-based formulations containing pumpkin seed oil and hemp seed oil for internal use." In The 8th International Conference on Advanced Materials and Systems. INCDTP - Leather and Footwear Research Institute (ICPI), Bucharest, Romania, 2020. http://dx.doi.org/10.24264/icams-2020.ii.1.

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With a long tradition in pharmaceutical design, emulsions are functional formulations that can maintain their adaptive power connected with the new formulation requirements. Hence, this study proposed preliminary assays concerning the obtaining of natural emulsions for oral administration, incorporating pumpkin seed oil and hemp seed oil as oil phases, with lecithin as emulsifying agent. Using emulsification method, O/W and W/O emulsions were prepared and characterized from a stability point of view considering organoleptic parameters, conductivity properties followed by an extensive superfici
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Cho, Jay, Scarlett R. Miller, Timothy W. Simpson, and Steven B. Shooter. "Effects of Over-the-Counter Medication Product Family Packaging Design on Knowledge Acquisition and Consumer Preferences." In ASME 2014 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/detc2014-35328.

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Adverse drug events result in hospitalization of more than 1.5 million Americans each year leading to large increases in health care costs. Although researchers have shown that a large portion of these adverse drug events are preventable, most Americans admit to only reading portions of over-the-counter (OTC) labeling, and only half say they seek out information on the label for usage information when they take an OTC medication for the first time. It is important then that we carefully consider what packaging features can motivate consumers to more thoughtfully consider the use of the OTC med
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Anene-Nzelu, Chukwuemeka G., Deepak Choudhury, Huipeng Li, et al. "Gratings on a Dish: A Scalable Cell Alignment Substrate on Optical Media." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14109.

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Cell alignment by underlying topographical cues has been shown to affect important biological processes such as differentiation and functional maturation in vitro. However, the routine use of cell culture substrates with micro/nano-topographies is currently hampered by the high cost and specialized facilities required to produce these substrates. Here we present commercially available optical media as substrates for aligning cells in culture. These optical media, including CD-R, DVD-R and optical grating, allow different cell types to attach, align and grow on them. This cytoskeletal reorganiz
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Иманов, Э. А. "Использование современных препаратов в комплексном лечении и профилактика воспалительных заболеваний пародонта у детей". У Наука России: Цели и задачи. НИЦ "LJournal", 2021. http://dx.doi.org/10.18411/sr-10-06-2021-04.

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In the study process participated schoolсhildren with diagnosis of chronic catarrhal gingivitis (HKG) and chronic periodontitis light form (HPLC). In total 103 patient, 67 patient with chronic catarrhal gingivitis and 36 patient with chro nic periodontitis light form. The laboratory results showed that in the process of conducting treatment and preventive measures during the use of the drug Loroben the functional activity of the local immune factors were significantly restored. If we pay attention to indicators after professional hygiene and local application of a solution of digluconate of ch
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Reports on the topic "Functional Drug Use"

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Allen, Luke, Joon Lim, Robert Haehnel, and Ian Dettwiller. Helicopter rotor blade multiple-section optimization with performance. Engineer Research and Development Center (U.S.), 2021. http://dx.doi.org/10.21079/11681/41031.

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This paper presents advancements in a surrogate-based, rotor blade design optimization framework for improved helicopter performance. The framework builds on previous successes by allowing multiple airfoil sections to designed simultaneously to minimize required rotor power in multiple flight conditions. Rotor power in hover and forward flight, at advance ratio 𝜇 = 0.3, are used as objective functions in a multi-objective genetic algorithm. The framework is constructed using Galaxy Simulation Builder with optimization provided through integration with Dakota. Three independent airfoil sections
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Halker Singh, Rashmi B., Juliana H. VanderPluym, Allison S. Morrow, et al. Acute Treatments for Episodic Migraine. Agency for Healthcare Research and Quality (AHRQ), 2020. http://dx.doi.org/10.23970/ahrqepccer239.

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Objectives. To evaluate the effectiveness and comparative effectiveness of pharmacologic and nonpharmacologic therapies for the acute treatment of episodic migraine in adults. Data sources. MEDLINE®, Embase®, Cochrane Central Registrar of Controlled Trials, Cochrane Database of Systematic Reviews, PsycINFO®, Scopus, and various grey literature sources from database inception to July 24, 2020. Comparative effectiveness evidence about triptans and nonsteroidal anti-inflammatory drugs (NSAIDs) was extracted from existing systematic reviews. Review methods. We included randomized controlled trials
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Chou, Roger, Jesse Wagner, Azrah Y. Ahmed, et al. Treatments for Acute Pain: A Systematic Review. Agency for Healthcare Research and Quality (AHRQ), 2020. http://dx.doi.org/10.23970/ahrqepccer240.

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Objectives. To evaluate the effectiveness and comparative effectiveness of opioid, nonopioid pharmacologic, and nonpharmacologic therapy in patients with specific types of acute pain, including effects on pain, function, quality of life, adverse events, and long-term use of opioids. Data sources. Electronic databases (Ovid® MEDLINE®, PsycINFO®, Embase®, the Cochrane Central Register of Controlled Trials, and the Cochrane Database of Systematic Reviews) to August 2020, reference lists, and a Federal Register notice. Review methods. Using predefined criteria and dual review, we selected randomiz
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Stall, Nathan M., Kevin A. Brown, Antonina Maltsev, et al. COVID-19 and Ontario’s Long-Term Care Homes. Ontario COVID-19 Science Advisory Table, 2021. http://dx.doi.org/10.47326/ocsat.2021.02.07.1.0.

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Key Message Ontario long-term care (LTC) home residents have experienced disproportionately high morbidity and mortality, both from COVID-19 and from the conditions associated with the COVID-19 pandemic. There are several measures that could be effective in preventing COVID-19 outbreaks, hospitalizations, and deaths in Ontario’s LTC homes, if implemented. First, temporary staffing could be minimized by improving staff working conditions. Second, homes could be further decrowded by a continued disallowance of three- and four-resident rooms and additional temporary housing for the most crowded h
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