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1

Talmage, James B. "Literature Review." Guides Newsletter 2, no. 3 (1997): 6. http://dx.doi.org/10.1001/amaguidesnewsletters.1997.mayjun03.

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Abstract Functional capacity testing typically involves musculoskeletal evaluations using instruments such as inclinometers, goniometers, range-of-motion machines, and strength analyzers. Depending on the organ system to be tested, a variety of tests are available to assess physiological competency (eg, liver function or renal function tests). The cardiopulmonary exercise test (CP Ex test) is one test that defines work capacity and addresses the two primary issues necessary for muscle movement: the adequacy of the cardiac output and that of the lungs to acquire oxygen and excrete carbon dioxid
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Abdyrakhmanova, Dzhiparkul, Bakyt Tynalieva, Emiliia Bolzhirova, and Bekzhan Аbdyrakhmanov. "Indicators of external respiratory system of people aged 50-55 during ethnical games of the kyrgyz people in the middle mountains region." SCIENCE AND SPORT: current trends 7, no. 3 (2019): 94–99. http://dx.doi.org/10.36028/2308-8826-2019-7-3-94-99.

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Ethnical outdoor games affect all muscle groups and have a positive effect on respiratory system. When studying indicators of external respiratory system (chest excursion, lungs capacity, respiratory rate, Stange and Genchi tests), we can assess the impact of ethnic outdoor games on human body. Purpose: to reveal improvement of indicators of the respiratory system of people aged 50-55 during ethnical games of Kyrgyz people in the middle mountains region. Research methods and organization. The analysis of scientific and methodical literature was carried out with the use of the following methods
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Ananyeva, L. P., I. E. Tyurin, O. A. Koneva, L. A. Garzanova, and A. M. Lila. "Interstitial lung disease in systemic sclerosis (systemic scleroderma)." Modern Rheumatology Journal 15, no. 1S (2021): 1–62. http://dx.doi.org/10.14412/1996-7012-2021-1s-1-62.

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In systemic sclerosis (SSc), interstitial lung disease (ILD) is common (>80%) and worsens the prognosis of the disease, but severe progressive damage develops only in 8–10% of cases. Interstitial changes in the lungs occur early (within the first 3–5 years of the disease). The histological manifestations are similar to those of idiopathic ILD.The main tool for screening and diagnosing of ILD associated with SSc is high-resolution computed tomography of the lungs, resulting data influence the choice of therapy. In most patients a relatively intact and stable forced vital capacity of the lung
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Zapevalova, Elena Yu, Julia B. Klyukhina, Evgeniya V. Boitsova, and Marina A. Kirbyatieva. "Clinical current and structural changes of pulmonary tissue at children with a bronchopulmonary dysplasia in the anamnesis." Pediatrician (St. Petersburg) 7, no. 1 (2016): 50–57. http://dx.doi.org/10.17816/ped7150-57.

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Bronchopulmonary dysplasia is currently the most common chronic lung disease in preterm infants. Since the initial description of the disease, more than forty years ago, new treatments and technologies have improved the outcome for preterm infants with very - low and extremely - low - birth - weight. As a result, the survival of extremely premature infants has increased but, despite of the improvement in neonatal care, the incidence of bronchopulmonary dysplasia continues to grow. At the same time the consequences of this disease for life has not yet been determined. The aim of the study to de
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Vasconcelos, Luciano Góis, Sonia Maria Dozzi Brucki, and Orlando Francisco Amodeo Bueno. "Cognitive and functional dementia assessment tools: Review of Brazilian literature." Dementia & Neuropsychologia 1, no. 1 (2007): 18–23. http://dx.doi.org/10.1590/s1980-57642008dn10100004.

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Abstract The diagnosis of dementia is based on cognitive and functional evaluation. One of the difficulties in ascertaining the number of people with dementia in developing countries is the population's lack of formal education. Independent effects of age, sex and education have been identified on scores for most but not all cognitive tests. Objectives: Identify the most-used cognitive and functional assessment tools in Brazil, related to dementia diagnosis and treatment outcome; and identify adaptations or normative data, when available. Methods: Data were generated from PubMed, LILACS and Po
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Wanot, Bartosz, Anna Stelmach, and Agnieszka Biskupek-Wanot. "CHRONIC OBSTRUCTIVE PULMONARY DISEASE - CRITERIA FOR DIAGNOSIS." Scientific Journal of Polonia University 27, no. 2 (2018): 128–35. http://dx.doi.org/10.23856/2715.

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The tests used to diagnose chronic obstructive pulmonary disease (COPD) can be divided into three groups. These a functional examination, imaging examinations and other tests helpful in the assessment of the disease's advancement. The basic test for suspicion of COPD is spirometry. It can be used to assess lung function noninvasively and quickly. Spirometry allows evaluation of volume components and components of air flow velocity in the lungs. Blood gas measurement is also helpful. Imaging examinations used in the diagnosis of COPD include chest radiograph and computed tomography. The results
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Maj, M., and K. Pietrzak. "Characteristics of Non-Ferrous Metal Alloys as Determined by Low-Cycle Fatigue Test under Variable Loads." Archives of Foundry Engineering 14, no. 1 (2014): 71–74. http://dx.doi.org/10.2478/afe-2014-0017.

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Abstract The paper presents the results of comparative tests of the fatigue properties conducted on two non-ferrous alloys designated as Al 6082 and Al 7075 which, due to the satisfactory functional characteristics, are widely used as engineering materials. The fatigue tests were carried out using a proprietary, modified low cycle test (MLCF). Particular attention was paid to the fatigue strength exponent b and fatigue ductility exponent c. Based on the tests carried out, the results comprised within the range defined by the literature were obtained. These results prove a satisfactory sensitiv
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Simic, Dusica, Nebojsa Ladjevic, Miodrag Milenovic, Angelina Bogicevic, Veljko Strajina, and Radmilo Jankovic. "Preoperative preparation of patients with infectious and restrictive respiratory diseases as comorbidities." Acta chirurgica Iugoslavica 58, no. 2 (2011): 63–69. http://dx.doi.org/10.2298/aci1102063s.

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In patients with respiratory pathology changes in respiratory physiology may lead to clinical problems during the conduct of anesthesia and the perioperative period. An understanding of the disease processes that can affect the lungs and pleura allows the anesthesiologist to account for the potential complications of these conditions and manage the anesthetic accordingly. This article describes the initial evaluation of a patient with respiratory problems. A thorough medical history, physical examination and some functional tests are the keys in decision-making in preparation for anesthesia an
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Замазій, А. А., та М. Д. Камбур. "ВИЗНАЧЕННЯ ФУНКЦІОНАЛЬНОГО СТАНУ ОРГАНІЗМУ НОВОНАРОДЖЕНИХ ТЕЛЯТ". Вісник Полтавської державної аграрної академії, № 4 (27 грудня 2012): 80–84. http://dx.doi.org/10.31210/visnyk2012.04.20.

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Результати досліджень, наведені у статті, свід-чать, що телята народжуються з різним рівнемфункціонального стану організму. Пренатальненедорозвинення тварин формується за умов пору-шення перебігу фізіологічних процесів на ґрунтінедостатнього забезпечення організму оксигеном.Наявність постійного контакту легенів із навко-лоплідною рідиною дає підстави апріорно вважа-ти, що за якісним складом амніотичної рідиниможна судити про стан плода, «зрілість сурфак-тантної системи легень» і процесами, що в нійвідбуваються, на що вказують окремі дослідженінами параметри. У зв’язку з цим ми пропонуємо20-бал
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Nesheva, Ir. "STUDY OF RESULTS BETWEEN INITIAL AND FINAL SPECIFIC TESTS IN WOMEN WITH NORMAL PREGNANCY." Trakia Journal of Sciences 17, no. 2 (2019): 135–42. http://dx.doi.org/10.15547/tjs.2019.02.006.

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PURPOSE: The aim of this study was to achieve a control model of basic functional indicators established by comparative analysis between the results of initial and final anthropometric and functional tests in women with normal pregnancy. METHODS: The research was done among 112 individuals, all Bulgarians, in the period 2015-2018, ages 21 to 31 years old. In order to fulfil the aim of the research we used: functional tests for assessing the effects of our original program build for the specific needs of pregnant women. The program content was branded under our family name: “Gym program for pre
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Leshchii, Nataliia. "FUNCTIONAL STATE OF THE CARDIORESPIRATORY SYSTEM OF YOUTH CHILDREN WITH COMPLEX DEVELOPMENTAL DISORDERS." Science and Education 2019, no. 2 (2019): 56–64. http://dx.doi.org/10.24195/2414-4665-2019-2-9.

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The article deals with the problem of diagnostics of functional state of the cardiorespiratory system of youth children who have complex developmental disorders. The physical, functional and psychological state of the child are an integral whole and any physical disturbance necessarily causes changes in the psychological and functional status of the child, which must be taken into account during performing physical education and health measures. The system of operational assessment of physical development and the results of physical culture and recreational work is an integral part of planning
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González Rendón, Elena S., Gumaro Gutierrez Cano, M. Alcaraz-Zubeldia, Tania Garibay-Huarte, and Teresa I. Fortoul. "Lead inhalation and hepatic damage: Morphological and functional evaluation in mice." Toxicology and Industrial Health 34, no. 2 (2018): 128–38. http://dx.doi.org/10.1177/0748233717750981.

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Lead (Pb) is a heavy metal that plays an unknown biological role and is very toxic even at low concentrations. The main sources of Pb are Pb-contaminated areas in industrial areas or landfills. Inhalation is one of the most common routes of exposure to this metal, but there is little information on its effect on the liver. Thirty male mice were exposed to 0.1 M Pb acetate by inhalation for 8 weeks, twice a week for 1h. A recovery group was free of exposure for 4 weeks. Histological evaluation showed an increase in the inflammatory infiltrate and in the percentage of meganuclei in the liver. Th
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Geske, Rita, Alevtīna Leice, Iveta Strode, and Maira Lāce. "MEDICAL COLLEGE STUDENTS HEALTH CHANGES DURING THE STUDY PERIOD." SOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference 3 (May 26, 2017): 348. http://dx.doi.org/10.17770/sie2017vol3.2248.

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The goal of this research is to analyze the change of students’ physical health during the one year of studies in context of lifestyle. The research participants were 103 Medical College’s students aged 19 to 56 years. All tests, measurements and questionnaires were done at falls of 2015 and 2016. Students’ physical health was evaluated in accordance with Apanasenko’s methods based on investigative anthropometric and functional testing measurements. These measurements included body mass index, lungs vital capacity, strength index, Robinson index and Recovery Heart Rate. Students’ lifestyle hab
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Bondi, Danilo, Giulia Prete, Gianluca Malatesta, and Claudio Robazza. "Laterality in Children: Evidence for Task-Dependent Lateralization of Motor Functions." International Journal of Environmental Research and Public Health 17, no. 18 (2020): 6705. http://dx.doi.org/10.3390/ijerph17186705.

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The behavioral preference for the use of one side of the body starts from pre-natal life and prompt humans to develop motor asymmetries. The type of motor task completed influences those functional asymmetries. However, there is no real consensus on the occurrence of handedness during developmental ages. Therefore, we aimed to determine which motor asymmetries emerged differently during childhood. A total sample of 381 children in grades 1 to 5 (6–11 years old) of primary school were recruited and tested for two fine coordination tasks (Floppy, led by dexterity, and Thumb, led by speed-dominat
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Dumitriu, Simina Dumitriţa, Zofia Dubicka, and Viorel Ionesi. "The functional significance of the spinose keel structure of benthic foraminifera: inferences from <i>Miliolina cristata</i> Millett, 1898 (Miliolida) from northeast Romania." Journal of Micropalaeontology 37, no. 1 (2018): 153–66. http://dx.doi.org/10.5194/jm-37-153-2018.

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Abstract. The paper presents Miocene (lower Sarmatian) benthic foraminifera from the FH3P1 Rădăuţi Core section from the northwestern part of the Moldavian Platform, Romania. Based on foraminiferal assemblages we infer sediments were deposited in shallow-water, including marine-marginal environments, of varying salinities from brackish to normal marine with some short and rather small sea-level changes. Moreover, we describe for the first time in the Moldavian Platform a very rare species, Miliolina cristata Millett, which presents a characteristic spinose keel. Based on a detailed study of th
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Caviezel, Claudio, Tamara Froehlich, Didier Schneiter, et al. "Identification of target zones for lung volume reduction surgery using three-dimensional computed tomography rendering." ERJ Open Research 6, no. 3 (2020): 00305–2020. http://dx.doi.org/10.1183/23120541.00305-2020.

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BackgroundThe key issues for performing lung volume reduction surgery (LVRS) is the identification of the target zones. Recently introduced three-dimensional computed tomography rendering methods are used to identify the morphological distribution and its severity of lung emphysema by densitometry. We demonstrate a new software for emphysema imaging and show the pre- and post-operative results in patients undergoing LVRS planned based on this new technology.MethodsA real-time three-dimensional image analysis software system was used pre- and 3 months post-operatively in five patients with hete
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Campoverde Molina, Milton, Jenny Vizñay Durán, and Silvia Vintimilla Jara. "Análisis de esquemas de metadatos para catalogación de tesis y proyectos de investigación." Revista Científica y Tecnológica UPSE 5, no. 1 (2018): 1–8. http://dx.doi.org/10.26423/rctu.v5i1.209.

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Este artículo revela el análisis comparativo de los esquemas de metadatos MARC21, MODS, DUBLIN CORE y OPAC en la catalogación y publicación de tesis y proyectos de investigación en el repositorio DSpace. Inicia con la elaboración y aplicación de una encuesta a los administradores bibliotecarios de las instituciones: Universidad de Cuenca, Universidad del Azuay, Universidad Católica de Cuenca, Universidad Politécnica Salesiana y la Biblioteca Municipal de la ciudad de Cuenca, con el fin de determinar el esquema de metadatos empleado en la catalogación de tesis y proyectos de investigación. Lueg
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Papuc, Alexandru, Ioan Mihai Japie, Traian Ciobanu, Octavian Nutiu, Dragos Radulescu, and Radu Radulescu. "GCT of knee treated with modular prosthesis-case presentation." Romanian Journal of Orthopaedic Surgery and Traumatology 2, no. 1 (2019): 18–22. http://dx.doi.org/10.2478/rojost-2019-0004.

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AbstractThe GCT is an aggressive benign tumor with metastatic potential, most often within the lungs in 2-3% of the patients. It makes about 5% of total bone tumors and about 15% of total benign bone tumors.The maximum incidence occurs between 30 and 40 years old, most frequently affecting the long bones epiphysis (distal femur, proximal tibia, and distal radius).We report the case of a 50-year-old female, with no previous medical history, admitted in the emergency department (ED) for significant pain and functional impairment of the left knee. Clinical examination and imaging tests establishe
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Davis, Richard J., Weiping Shen, Yakov I. Sandler, et al. "Dach1 Mutant Mice Bear No Gross Abnormalities in Eye, Limb, and Brain Development and Exhibit Postnatal Lethality." Molecular and Cellular Biology 21, no. 5 (2001): 1484–90. http://dx.doi.org/10.1128/mcb.21.5.1484-1490.2001.

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ABSTRACT Drosophila dachshund is necessary and sufficient for compound eye development and is required for normal leg and brain development. A mouse homologue of dachshund, Dach1, is expressed in the developing retina and limbs, suggesting functional conservation of this gene. We have generated a loss-of-function mutation in Dach1 that results in the abrogation of the wild-type RNA and protein expression pattern in embryos. Homozygous mutants survive to birth but exhibit postnatal lethality associated with a failure to suckle, cyanosis, and respiratory distress. The heart, lungs, kidneys, live
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Tovena, Lucia M., and Marleen Van Peteghem. "Différent vs autre et l’opposition réciproque vs comparatif." Lingvisticæ Investigationes. International Journal of Linguistics and Language Resources 25, no. 1 (2002): 149–70. http://dx.doi.org/10.1075/li.25.1.09tov.

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Summary This paper tests on French Beck’s (2000) analysis of plural and quantified NP dependent readings of different in English. According to her, different works as a relational adjective when it depends on a plural NP, and as a comparison operator when it depends on a universally quantified NP. Beck treats as evidence in favour of her thesis the fact that German uses two distinct ‘different’ (verschieden and ander) to produce the range of possible readings of different in English. We show, however, that the opposition between différent and autre in French does not locate the border of lexic
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Vygovskaya, Svetlana N., Alexey A. Voropaev, Tatyana V. Konchugova, and Elena M. Styazhkina. "Features of medical rehabilitation of patients who have suffered an ischemic stroke and have a history of obstructive chronic disorders of the respiratory system without exacerbation." Russian Journal of Physiotherapy, Balneology and Rehabilitation 19, no. 5 (2021): 299–304. http://dx.doi.org/10.17816/1681-3456-2020-19-5-4.

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Background. To date, the study of respiratory function in the clinic is limited, as a rule, to the determination of bronchial conduction indicators, as well as bronchodilation tests, which at the present stage is insufficient for a deep assessment of the functional state of patients with chronic obstructive pulmonary disease.&#x0D; Aims. The development of personalized medical rehabilitation programs for patients who have undergone ischemic stroke at various stages of rehabilitation, including spa.&#x0D; Materials and methods. The article considers the effectiveness of the new method of treati
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Loginova, I. Yu, O. V. Kamenskaya, A. V. Fomichev, D. V. Doronin, A. M. Chernyavskiy, and V. V. Lomivorotov. "Functional state of the cardiorespiratory system after orthotopic heart transplantation with prolonged cold ischemia time." Russian Journal of Transplantology and Artificial Organs 22, no. 3 (2020): 53–61. http://dx.doi.org/10.15825/1995-1191-2020-3-53-61.

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Objective: to assess the functional state of the cardiorespiratory system in the long term after orthotopic heart transplantation (HT) with prolonged cold ischemia time. Materials and methods. The results of 60 orthotopic HTs performed at Meshalkin National Medical Research Center were analyzed. A comparison was made of the immediate and long-term outcomes of HTs in the group with cold ischemia time lasting for less than 240 minutes and in those with farther distance between donor and recipient sites with cold ischemia time of 240 minutes or more. In the long-term follow-up after HT, all patie
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Ellis, E. R., R. B. Marcus, M. J. Cicale, et al. "Pulmonary function tests after whole-lung irradiation and doxorubicin in patients with osteogenic sarcoma." Journal of Clinical Oncology 10, no. 3 (1992): 459–63. http://dx.doi.org/10.1200/jco.1992.10.3.459.

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PURPOSE Because of the scarcity of information regarding long-term follow-up of pulmonary function after whole-lung irradiation, a prospective study was started at the University of Florida in 1979 to evaluate pulmonary function after treatment with whole-lung irradiation and doxorubicin in patients with osteogenic sarcoma. PATIENTS AND METHODS Between 1979 and 1984, 57 osteogenic sarcoma patients with no evidence of metastatic disease at diagnosis received adjuvant therapy consisting of whole-lung irradiation (with the heart shielded) followed by Adriamycin (doxorubicin; Adria Laboratories, C
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Wang, Jennifer M., Scott H. Robertson, Ziyi Wang, et al. "Using hyperpolarized 129Xe MRI to quantify regional gas transfer in idiopathic pulmonary fibrosis." Thorax 73, no. 1 (2017): 21–28. http://dx.doi.org/10.1136/thoraxjnl-2017-210070.

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BackgroundAssessing functional impairment, therapeutic response and disease progression in patients with idiopathic pulmonary fibrosis (IPF) continues to be challenging. Hyperpolarized 129Xe MRI can address this gap through its unique capability to image gas transfer three-dimensionally from airspaces to interstitial barrier tissues to red blood cells (RBCs). This must be validated by testing the degree to which it correlates with pulmonary function tests (PFTs) and CT scores, and its spatial distribution reflects known physiology and patterns of disease.Methods13 healthy individuals (33.6±15.
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Gie, Andre George, Thomas Salaets, Janne Vignero, et al. "Intermittent CPAP limits hyperoxia-induced lung damage in a rabbit model of bronchopulmonary dysplasia." American Journal of Physiology-Lung Cellular and Molecular Physiology 318, no. 5 (2020): L976—L987. http://dx.doi.org/10.1152/ajplung.00465.2019.

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A significant proportion of preterm infants develop bronchopulmonary dysplasia (BPD) leading to poor lifelong respiratory health. Limited treatment options exist with continuous positive airway pressure (CPAP) ventilation being one of the few associated with diminished BPD. However, little is known about the effect of the distending pressure of CPAP on the developing lung exposed to hyperoxia. We aimed to identify the functional and structural effects of CPAP in a preterm hyperoxia rabbit model of BPD. Premature rabbit pups were randomized to normoxia, hyperoxia (≥95% O2), or hyperoxia plus 4
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Savushkina, O. I., A. V. Cherniak, E. V. Kryukov, et al. "Pulmonary function after COVID-19 in early convalescence phase." Medical alphabet, no. 25 (October 26, 2020): 7–12. http://dx.doi.org/10.33667/2078-5631-2020-25-7-12.

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Pulmonary function after COVID-19 in early convalescence phase. The aim of the study is to investigate the influence of Coronavirus disease 2019 (COVID-19) on pulmonary function in early convalescence phase.Materials and methods. The study included 44 patients (35 male) after COVID-19 without concomitant bronchopulmonary pathology, with a median age of 47.5 years. All patients underwent standard pulmonary function tests (PFTs): spirometry, body plethysmography, diffusion test. Besides, dyspnea on the mMRC scale was assessed, oxygen saturation level (SpO2 ) was measured. Depending on degree of
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Andriyashkina, D. Yu, N. A. Demidova, N. A. Shostak, N. A. Tutaev, A. D. Ershov, and D. K. Dudin. "PULMONARY-RENAL SYNDROME: DIFFICULTIES OF DIFFERENTIAL DIAGNOSIS." Clinician 12, no. 2 (2018): 43–50. http://dx.doi.org/10.17650/1818-8338-2018-2-43-50.

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The study objective is to demonstrate the difficulty of differential diagnosis in pulmonary-renal syndrome using a clinical case as an example.Materials and methods. Male patient A., 68 years old, retired, was hospitalized at the N.I. Pirogov City Clinical Hospital № 1 in December of 2017 with complaints of inefficient cough, fever of 39 °С, weakness, apnea, weight loss up 10 kg in 3 months. Examination revealed skin and mucosa paleness, calf edema, heart beat of 102 bpm, normal rhythm, arterial pressure 130/80 mm Hg, respiratory rate 22 breaths per min. Auscultation revealed harsh respiration
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Zolotnitskaya, V. P., O. N. Titova, O. V. Lukina, and E. I. Bobrov. "Pulmonary embolism in combination with a reversible and irreversible airflow obstruction." Regional blood circulation and microcirculation 16, no. 1 (2017): 27–31. http://dx.doi.org/10.24884/1682-6655-2017-16-1-27-31.

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Pulmonary thromboembolism, combined with bronchial obstruction is the most difficult in the diagnosis, because it can be presented as a combination of unventilated and not perfused areas and this disorders can occur in the acute phase of embolism, and also in long-term period after the onset. Aim: To evaluate influence of different disorders of blood circulation in the lungs on the development of bronchial obstruction in patients with different forms of PE. Material and Methods: We analyzed of the results of radiological methods: perfusion scintigraphy, single photon emission computed tomograp
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Hartsfield, C. L., D. Lipke, Y. L. Lai, D. A. Cohen, and M. N. Gillespie. "Pulmonary mechanical and immunologic dysfunction in a murine model of AIDS." American Journal of Physiology-Lung Cellular and Molecular Physiology 272, no. 4 (1997): L699—L706. http://dx.doi.org/10.1152/ajplung.1997.272.4.l699.

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Human immunodeficiency virus-infected patients occasionally exhibit alveolar septal wall thickening and decreases in gas diffusion capacity, but the mechanism underlying these abnormalities is unknown. The present study evaluated septal wall thickness and gas exchange properties in a murine model of the acquired immunodeficiency syndrome and determined whether there were alterations in lung lymphocyte deposition and activation that could contribute to changes in respiratory structure and function. Although alveolar septal wall thickness did not differ from control at 1, 2, and 4 wk postimmunos
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Boulet, Louis-Philippe, Hélène Turcotte, Catherine Hudon, Guy Carrier, and François Maltais. "Clinical, Physiological and Radiological Features in Asthma with Incomplete Reversibility of Airflow Obstruction Compared with Those of COPD." Canadian Respiratory Journal 5, no. 4 (1998): 270–77. http://dx.doi.org/10.1155/1998/780739.

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OBJECTIVES: To compare clinical features, pulmonary function and high-resolution computed chest tomography (HRCT) findings of asthmatic patients with a component of incomplete reversibility of airflow obstruction (AIRAO) with those of patients with smoking-induced chronic obstructive pulmonary disease (COPD).METHODS: Thirteen patients with COPD (six males and seven females, mean age 59 years, mean smoking 50.5 pack-years) and 14 patients with AIRAO (six males and eight females, mean age 52 years) despite optimal treatment, with no significant smoking history (mean 1.5 pack-years) and no signif
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Harty, Helen R., Douglas R. Corfield, Richard M. Schwartzstein, and Lewis Adams. "External thoracic restriction, respiratory sensation, and ventilation during exercise in men." Journal of Applied Physiology 86, no. 4 (1999): 1142–50. http://dx.doi.org/10.1152/jappl.1999.86.4.1142.

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Multiple factors may contribute to the dyspnea associated with restrictive ventilatory disease (RVD). Simple models that examine specific features of this problem are likely to provide insight into the mechanisms. Previous models of RVD utilizing elastic loads may not represent completely the impact on pulmonary and chest wall receptors derived from breathing at low thoracic volumes. The purpose of this study was to investigate the sensory consequences of breathing at low lung volumes induced by external thoracic restriction in an attempt to further elucidate the etiology of dyspnea in this se
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Hamers, Anouk A. J., Sven Uleman, Claudia M. van Tiel, et al. "Limited Role of Nuclear Receptor Nur77 in Escherichia coli-Induced Peritonitis." Infection and Immunity 82, no. 1 (2013): 253–64. http://dx.doi.org/10.1128/iai.00721-13.

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ABSTRACTNuclear receptor Nur77 (NR4A1, TR3, or NGFI-B) has been shown to play an anti-inflammatory role in macrophages, which have a crucial function in defense against peritonitis. The function of Nur77 inEscherichia coli-induced peritoneal sepsis has not yet been investigated. Wild-type and Nur77-knockout mice were inoculated withE. coli, and bacterial outgrowth, cell recruitment, cytokine profiles, and tissue damage were investigated. We found only a minor transient decrease in bacterial loads in lung and liver of Nur77-knockout compared to wild-type mice at 14 h postinfection, yet no chang
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Darbee, Joan C., Patricia J. Ohtake, Brydon JB Grant, and Frank J. Cerny. "Physiologic Evidence for the Efficacy of Positive Expiratory Pressure as an Airway Clearance Technique in Patients With Cystic Fibrosis." Physical Therapy 84, no. 6 (2004): 524–37. http://dx.doi.org/10.1093/ptj/84.6.524.

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Abstract Background and Purpose. Individuals with cystic fibrosis (CF) have large amounts of infected mucus in their lungs, which causes irreversible lung tissue damage. Although patient-administered positive expiratory pressure (PEP) breathing has been promoted as an effective therapeutic modality for removing mucus and improving ventilation distribution in these patients, the effects of PEP on ventilation distribution and gas mixing have not been documented. Therefore, this preliminary investigation described responses in distribution of ventilation and gas mixing to PEP breathing for patien
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34

Ravimohan, Shruthi, Sara C. Auld, Pholo Maenetje, et al. "Lung Injury on Antiretroviral Therapy in Adults With Human Immunodeficiency Virus/Tuberculosis." Clinical Infectious Diseases 70, no. 9 (2019): 1845–54. http://dx.doi.org/10.1093/cid/ciz560.

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Abstract Background Immune restoration on antiretroviral therapy (ART) can drive inflammation in people living with human immunodeficiency virus (HIV) who have pulmonary tuberculosis (TB), but its effects on the lungs have not been assessed. We evaluated associations between pulmonary inflammation, recovery of pathogen-specific CD4 T-cell function, and lung injury prior to and after ART initiation in adults with HIV and pulmonary TB. Methods This was a prospective cohort study in South Africa, following adults with HIV and pulmonary TB prior to and up to 48 weeks after ART initiation. Pulmonar
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35

Murray, Margaret, Aimee L. Dordevic, Katherine H. M. Cox, Andrew Scholey, Lisa Ryan, and Maxine P. Bonham. "Study protocol for a double-blind randomised controlled trial investigating the impact of 12 weeks supplementation with aFucus vesiculosusextract on cholesterol levels in adults with elevated fasting LDL cholesterol who are overweight or have obesity." BMJ Open 8, no. 12 (2018): e022195. http://dx.doi.org/10.1136/bmjopen-2018-022195.

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IntroductionHyperlipidaemia, hyperglycaemia and chronic inflammation are risk factors for chronic diseases cardiovascular disease and type 2 diabetes. Polyphenols are bioactive compounds found in marine algae with potential antihyperlipidaemic, antihyperglycaemic and anti-inflammatory effects. The modulation of these risk factors using bioactive polyphenols may represent a useful strategy for disease prevention and management; research in humans, however, remains limited. This trial aims to determine the impact of a polyphenol-rich brown seaweed extract on fasting hyperlipidaemia, hyperglycaem
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36

Benavidez, F., G. Rodriguez, A. Riopedre, et al. "FRI0056 LUNG COMPROMISE SCREENING IN PATIENTS WITH EARLY RA. A MULTICENTRIC CROSS SECTIONAL STUDY." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 604.1–604. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1003.

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Background:Rheumatoid arthritis (RA) affects 0.4-1.3% of general population (1). It can affect lungs in different ways, with interstitial lung disease (ILD) as the most severe. Clinically evident ILD has been reported in 10-42% of patients, with a great impact in prognosis (2).Objectives:Toidentify the prevalence of lung involvement in early rheumatoid arthritis patients (ERA) without previous known lung disease and describe the association between high resolution computed tomography (HRCT), lung functional tests (LFT) and clinical findings.Methods:Cross sectional multicentric study. We includ
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De Andrade, Ikaro Alves, Igor Romeiro Dos Santos, Danielly Batista Borges Camargo, Thays Teixeira Linhares, and Rosângela Reis Da Silva. "Aspectos Morfofuncionais e Laboratoriais de Cryptococcus sp. Evidenciados na Criptococose." Revista de Patologia do Tocantins 4, no. 4 (2017): 34. http://dx.doi.org/10.20873/uft.2446-6492.2017v4n4p34.

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INTRODUÇÃO: A criptococose é uma patologia sistêmica decorrente da ação de leveduras do gênero Cryptococcus sp., em particular, as espécies C. neoformans e C. gattii. A doença acomete inicialmente os pulmões, todavia, os fungos apresentam forte tropismo para o tecido cerebral ocasionando a meningite criptocócica. Fatores como a atividade da cápsula proteica e as enzimas sintetizadas pelo fungo corroboram para a instauração da doença e, além disso, são parâmetros utilizados em testes laboratoriais para a detecção dos patógenos em amostras biológicas. OBJETIVO: Descrever os fatores comumente ass
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Alexseev, D., I. Nikishina, and L. Ananieva. "AB0743 SINGLE CENTER EXPERIENCE OF BIOLOGICAL THERAPY IN PATIENTS WITH JUVENILE SYSTEMIC SCLERODERMA." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1400.2–1400. http://dx.doi.org/10.1136/annrheumdis-2021-eular.3558.

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Background:Juvenile systemic scleroderma (jSSС) is a rare multisystem disease with a poor prognosis. The current therapy is imperfect. Biologics, as a modern efficient option for treatment of rheumatic diseases don`t have official indication for jSSС, but it seems to be useful in severe cases, especially lung and heart damage.Objectives:To analyze the existing experience of Biologics therapy in children with jSSС in single center in order to improve the understanding of the indications for use and the results of using these drugs.Methods:The retrospective study include 9 patients with jSSC wit
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Gutyj, B., I. Khariv, V. Binkevych та ін. "Research on acute and chronic toxity of the experimental drug Аmprolinsyl". Regulatory Mechanisms in Biosystems 8, № 1 (2017): 41–45. http://dx.doi.org/10.15421/021708.

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The drug Amprolinsyl is a is a mixture of hydrochloric amprolium (12.5 g) and milled fruits of the milk thistle (up to 100 g), designed to prevent and treat protozoonoses in birds, especially when mixed associative invasions occur. The fruits of the milk thistle contain the natural vitamins (A, C, E, B) and the minerals (copper, iron, cobalt) and other factors that significantly expand and enhance the pharmacological effect of the drug Amprolinsyl. We found that when the drug Amprolinsyl was administered intra gastrically to white rats at a dose of 5000 mg/kg and higher clinical signs of toxic
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Ma, Hui-Hui, Biin Sung, Caisheng Lu, et al. "Interferon-Gamma Signaling in the Pathogenesis of Idiopathic Pneumonia Syndrome Following Allogeneic Bone Marrow Transplantation." Blood 126, no. 23 (2015): 3075. http://dx.doi.org/10.1182/blood.v126.23.3075.3075.

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Abstract Idiopathic pneumonia syndrome (IPS) is a life-threatening acute noninfectious diffuse lung injury occurring after allogeneic bone marrow transplantation (BMT). We have recently shown that absence of STAT1 signaling in recipient APC leads to accelerated Graft Versus Host Disease (GVHD) and Transplant-associated mortality and morbidity after lethal irradiation in fully MHC-mismatched allogeneic or in non-irradiated P→F1 BMT models. We now addressed the impact of recipient Type II interferon signaling on the development of lung injury after allogeneic BMT using a non-irradiated P→F1 mode
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41

Yarmolyuk, N. S., E. A. Biryukova, E. R. Dzheldubaeva, et al. "COMPARATIVE CHARACTERISTICS OF THE EXTERNAL BREATHING PARAMETERS OF YOUNG ATHLETES IN CYCLIC SPORTS." Scientific Notes of V.I. Vernadsky Crimean Federal University. Biology. Chemistry 6(72), no. 2 (2020): 281–90. http://dx.doi.org/10.37279/2413-1725-2020-6-2-281-290.

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At present, one of the main tasks of the state is to develop and improve the system of health protection and quality of life of the younger generation. In this regard, the search for simple non-invasive methods of monitoring the health of children, and especially young athletes at various stages of their competitive activity, is of great importance. It is known that the leading place among the factors influencing sports performance is occupied by a number of authors with the peculiarities of metabolic processes of sportsmen [1, 2], hemodynamics [3, 4], neuromuscular activation [5, 6], activity
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42

Lopez Corbeto, M., and E. Moreno Ruzafa. "SAT0504 STING-ASSOCIATED VASCULOPATHY WITH ONSET IN INFANCY (SAVI SYNDROME) CAN MIMIC JUVENILE IDIOPATHIC ARTHRITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1208.2–1208. http://dx.doi.org/10.1136/annrheumdis-2020-eular.5819.

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Background:STING-associated vasculopathy with onset in infancy (SAVI syndrome) can mimic Juvenile Idiopathic Arthritis.Objectives:The aim of this study is to describe a detailed cohort of patients with SAVI syndrome and highlight the similarity, in some cases, of the phenotype of this disease with Juvenile Idiopathic Arthritis.Methods:3 patients diagnosed with SAVI syndrome from the institution Hospital Universitari Vall d’Hebron were recruited. Written informed parental consent was obtained for the use of clinical data and pictures reported. Demographic, clinical, analytical, lung function an
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Razumovsky, Aleksandr Yu, Abdumanap B. Alkhasov, Maksim P. Razin, et al. "Comparative characteristics of the efficiency of different methods of operational treatment for pectus excavatum in children: a multicenter study." Pediatric Traumatology, Orthopaedics and Reconstructive Surgery 6, no. 1 (2018): 5–13. http://dx.doi.org/10.17816/ptors615-13.

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Background. Congenital malformations of the chest are observed in 1%–4% of the population, and the most common among these is pectus excavatum (90%).&#x0D; Aim. We aimed to conduct a retrospective multicenter study to compare the effectiveness of various methods of operative removal of pectus excavatum in children.&#x0D; Material and methods. We retrospectively analyzed the results of the surgical treatment of funnel-like deformity of the thorax in children conducted in clinics of pediatric surgery in seven regions of Russia (1,226 patients). The ratio of boys to girls in the study population
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Cotton, DJ, JT Mink, and BL Graham. "Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers." Canadian Respiratory Journal 5, no. 2 (1998): 101–8. http://dx.doi.org/10.1155/1998/324920.

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BACKGROUND: Although centrilobular emphysema, and small airway, interstitial and alveoli inflammation can be detected pathologically in the lungs of smokers with relatively well preserved lung function, these changes are difficult to assess using available physiological tests. Because submaximal single breath washout (SBWSM) manoeuvres improve the detection of abnormalities in ventilation inhomogeneity in the lung periphery in smokers compared with traditional vital capacity manoeuvres, SBWSMmanoeuvres were used in this study to measure temporal differences in diffusing capacity using a rapid
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Szymańska, Jadwiga, Barbara Frydrych, and Elżbieta Bruchajzer. "Diesel engine exhaust, measured as elemental carbon. Documentation of proposed values of occupational exposure limits (OELs)." Podstawy i Metody Oceny Środowiska Pracy 35, no. 4(102) (2019): 43–109. http://dx.doi.org/10.5604/01.3001.0013.6378.

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Exhaust emissions from diesel engines (SESD) are multi-component mixtures of chemical compounds resulting from incomplete combustion of fuel and engine oil. The toxic effect of exhaust gases is associated with the presence of toxic and carcinogenic compounds in them. GIS reports in 2019 that the number of employees employed in conditions constituting 0.1– 0.5 of MAC-TWA (applicable for exhaust emissions from diesel engines) in 2017 and in 2018 was 1071 and 986, respectively, while in conditions 0 , 5–1 MAC-TWA were 26 and 46, respectively. In the list of occupational diseases in the years 2013
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46

Kharlamova, O. S., K. Y. Nikolayev, Y. I. Ragino, and M. I. Voyevoda. "Association of SP-A and SP-D Surfactant Proteins with the Severity of CommunityAcquired Pneumonia." Russian Sklifosovsky Journal "Emergency Medical Care" 9, no. 3 (2020): 348–55. http://dx.doi.org/10.23934/2223-9022-2020-9-3-348-355.

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Relevance. In current clinical practice, there is a need for research to find new diagnostic tests for the purpose of determining the patients with the highest risk of death from pneumonia. Surfactant proteins SP-A and SP-D play a key role in the pathogenesis of the response to microbial invasion of lung tissue, which participate in a cascade of reactions of both innate and adaptive immunity, and therefore proteins SP-A and SP-D may be considered as markers of the severity of community-acquired pneumonia (CAP).Aim of study. To evaluate the associations of surfactant proteins SP-A and SP-D in b
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47

Hayat, Anees, Asia Riaz, and Nazia Suleman. "Effect of gamma irradiation and subsequent cold storage on the development and predatory potential of seven spotted ladybird beetle Coccinella septempunctata Linnaeus (Coleoptera; Coccinellidae) larvae." World Journal of Biology and Biotechnology 5, no. 2 (2020): 37. http://dx.doi.org/10.33865/wjb.005.02.0297.

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Seven spot ladybird beetle, (Coccinella septempunctata) is a widely distributed natural enemy of soft-bodied insect pests especially aphids worldwide. Both the adult and larvae of this coccinellid beetle are voracious feeders and serve as a commercially available biological control agent around the globe. Different techniques are adopted to enhance the mass rearing and storage of this natural enemy by taking advantage of its natural ability to withstand under extremely low temperatures and entering diapause under unfavorable low temperature conditions. The key objective of this study was to de
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Thi Xuan, Bui, Ngo Tien Thanh, and To Khanh Linh. "Analysis of Direct Treatment Cost for Exacerbation of Chronic Obstructive Pulmonary Disease in E Hospital from October 2019 to March 2020." VNU Journal of Science: Medical and Pharmaceutical Sciences 36, no. 2 (2020). http://dx.doi.org/10.25073/2588-1132/vnumps.4242.

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This study analyzes the direct treatment cost for exacerbation of chronic obstructive pulmonary disease (COPD) at the Department of Pulmonology, E Hospital from October 2019 to March 2020. The study results show that the average direct treatment cost for exacerbation of COPD was VND 9,102,311.71; the highest cost was VND 36,304,614 and the lowest cost, VND 2,309,961. Among the direct treatment cost components, drug cost showed the highest proportion, followed by hospital bed, then surgical procedures, tests, diagnostic imaging, functional exploration, examination and medical supplies. The cost
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Shamrao Patil, Dr Vishal, and Dr (Mrs ). Manisha V. Bhalsing. "A Review on Functions of Rakt Dhatu and Prana Vayu to Establish Lung Function Capacity." International Journal of Innovative Research in Medical Science 3, no. 01 (2018). http://dx.doi.org/10.23958/ijirms/vol03-i01/13.

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Lung function tests are useful in assessing the functional status of Respiratory system in both in physiological as well as pathological conditions. These are based on the measurement of volume of air breathed in and out in quite breathing &amp; forced breathing. Air in lungs is classified in to two divisions’ lung volumes &amp; lung capacities. Lung Capacities are the combination of two or more lung volumes. The concept of Rakt Dhatu &amp; Vayu is important in case of respiration because Charaka says that pure blood provides the person with strength, luster &amp; happy life because vital brea
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Kreider, Maryl. "Pulmonary Function Testing." DeckerMed Family Medicine, August 25, 2017. http://dx.doi.org/10.2310/fm.1257.

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Intelligent management of pulmonary disease requires a fundamental understanding of the complex interrelationships between multiple elements that interact to maintain homeostasis in the respiratory system. This chapter discusses the physiologic basis for pulmonary function testing and the use of these tests to diagnose disease, quantitate functional impairments, and follow the effects of treatment. Figures illustrate the relationships between lung volume, airway conductance, and airway resistance; the relationship between forced expiratory volume and time (spirogram); the relationship between
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