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Journal articles on the topic 'Functional UltraSound'

Author: Grafiati

Published: 21 December 2024

Last updated: 31 July 2025

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1

Shatillo, Artem, Juho Koponen, Tuukka Miettinen, Anna-Mari Karkkainen, and Antti Nurmi. "Functional Ultrasound." Genetic Engineering & Biotechnology News 39, no. 4 (2019): 52–54. http://dx.doi.org/10.1089/gen.39.04.16.

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Montaldo, Gabriel, Alan Urban, and Emilie Macé. "Functional Ultrasound Neuroimaging." Annual Review of Neuroscience 45, no. 1 (2022): 491–513. http://dx.doi.org/10.1146/annurev-neuro-111020-100706.

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Functional ultrasound (fUS) is a neuroimaging method that uses ultrasound to track changes in cerebral blood volume as an indirect readout of neuronal activity at high spatiotemporal resolution. fUS is capable of imaging head-fixed or freely behaving rodents and of producing volumetric images of the entire mouse brain. It has been applied to many species, including primates and humans. Now that fUS is reaching maturity, it is being adopted by the neuroscience community. However, the nature of the fUS signal and the different implementations of fUS are not necessarily accessible to nonspecialis

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3

de Korte, Chris L., and Hendrik H. G. Hansen. "FOCUS: FUNCTIONAL IMAGING - ULTRASOUND." Artery Research 7, no. 3-4 (2013): 110. http://dx.doi.org/10.1016/j.artres.2013.10.387.

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4

Tyler, William J., Yusuf Tufail, and Sandipan Pati. "Noninvasive functional neurosurgery using ultrasound." Nature Reviews Neurology 6, no. 1 (2010): 13–14. http://dx.doi.org/10.1038/nrneurol.2009.211.

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Gilja, Odd Helge. "Ultrasound in functional GI disorders." Ultrasound in Medicine & Biology 45 (2019): S14—S15. http://dx.doi.org/10.1016/j.ultrasmedbio.2019.07.458.

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6

Martinez de Paz, Jose Maria, and Emilie Macé. "Functional ultrasound imaging: A useful tool for functional connectomics?" NeuroImage 245 (December 2021): 118722. http://dx.doi.org/10.1016/j.neuroimage.2021.118722.

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7

Lin, Yan, Zhi-Yi Chen, and Feng Yang. "Ultrasound-Based Multimodal Molecular Imaging and Functional Ultrasound Contrast Agents." Current Pharmaceutical Design 19, no. 18 (2013): 3342–51. http://dx.doi.org/10.2174/1381612811319180016.

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Lin, Yan, Zhi-Yi Chen, and Feng Yang. "Ultrasound-Based Multimodal Molecular Imaging and Functional Ultrasound Contrast Agents." Current Pharmaceutical Design 999, no. 999 (2013): 6–10. http://dx.doi.org/10.2174/13816128113198880008.

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9

Mourad, Pierre D., Daniel A. Lazar, Francesco P. Curra, et al. "Ultrasound Accelerates Functional Recovery after Peripheral Nerve Damage." Neurosurgery 48, no. 5 (2001): 1136–41. http://dx.doi.org/10.1097/00006123-200105000-00035.

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Abstract OBJECTIVE Axonal injury in the peripheral nervous system is common, and often it is associated with severe long-term personal and societal costs. The objective of this study is to use an animal model to demonstrate that transcutaneous ultrasound can accelerate recovery from an axonotmetic injury. METHODS The sciatic nerve of adult male Lewis rats was crushed in the right midthigh to cause complete distal degeneration of axons yet maintain continuity of the nerve. Beginning 3 days after surgery, various transcutaneous ultrasound treatments or sham treatments were applied 3 days per wee

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10

Macé, Emilie, Gabriel Montaldo, Ivan Cohen, Michel Baulac, Mathias Fink, and Mickael Tanter. "Functional ultrasound imaging of the brain." Nature Methods 8, no. 8 (2011): 662–64. http://dx.doi.org/10.1038/nmeth.1641.

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11

Rau, Richard, Pieter Kruizinga, Frits Mastik, et al. "3D functional ultrasound imaging of pigeons." NeuroImage 183 (December 2018): 469–77. http://dx.doi.org/10.1016/j.neuroimage.2018.08.014.

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Blomley, M. J. K., and R. J. Eckersley. "Functional ultrasound methods in oncological imaging." European Journal of Cancer 38, no. 16 (2002): 2108–15. http://dx.doi.org/10.1016/s0959-8049(02)00383-0.

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13

Bertholdt, C., M. Dap, M. Beaumont, J. Duan, and O. Morel. "New insights into human functional ultrasound imaging." Placenta 117 (January 2022): 5–12. http://dx.doi.org/10.1016/j.placenta.2021.10.005.

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14

Qiaonong, Wen, Xu Shuang, and Wan Suiren. "Ultrasound Image Deconvolution Based on Energy Functional." Journal of Nanoscience and Nanotechnology 16, no. 7 (2016): 6667–78. http://dx.doi.org/10.1166/jnn.2016.11363.

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Wen, Qiaonong, Shuang Xu, and Suiren Wan. "Ultrasound Image Segmentation Based on Energy Functional." Journal of Nanoscience and Nanotechnology 16, no. 9 (2016): 9359–70. http://dx.doi.org/10.1166/jnn.2016.12433.

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16

贺, 鑫媛. "Research Progress of Functional Ultrasound Imaging Technology." Journal of Clinical Personalized Medicine 03, no. 04 (2024): 1597–604. https://doi.org/10.12677/jcpm.2024.34229.

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17

Moon, Sunho, Xiangming Xue, Vidisha Ganesh, et al. "Ultrasound-Compatible Electrode for Functional Electrical Stimulation." Biomedicines 12, no. 8 (2024): 1741. http://dx.doi.org/10.3390/biomedicines12081741.

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Functional electrical stimulation (FES) is a vital method in neurorehabilitation used to reanimate paralyzed muscles, enhance the size and strength of atrophied muscles, and reduce spasticity. FES often leads to increased muscle fatigue, necessitating careful monitoring of the patient’s response. Ultrasound (US) imaging has been utilized to provide valuable insights into FES-induced fatigue by assessing changes in muscle thickness, stiffness, and strain. Current commercial FES electrodes lack sufficient US transparency, hindering the observation of muscle activity beneath the skin where the el

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18

Tyurnikov, V. M., and A. O. Gushcha. "High-Intensity Focused Ultrasound in Functional Neurosurgery." Human Physiology 43, no. 8 (2017): 916–21. http://dx.doi.org/10.1134/s036211971708014x.

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19

Bailao, L. A. "Ultrasound and Doppler in functional ovarian disturbances." Ultrasound in Medicine & Biology 29, no. 5 (2003): S75. http://dx.doi.org/10.1016/s0301-5629(03)00334-x.

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Yeh, C. K., K. W. Ferrara, and D. E. Kruse. "High-Resolution Functional Vascular Assessment With Ultrasound." IEEE Transactions on Medical Imaging 23, no. 10 (2004): 1263–75. http://dx.doi.org/10.1109/tmi.2004.834614.

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21

Yuan, Baohong, and Joshua Rychak. "Tumor Functional and Molecular Imaging Utilizing Ultrasound and Ultrasound-Mediated Optical Techniques." American Journal of Pathology 182, no. 2 (2013): 305–11. http://dx.doi.org/10.1016/j.ajpath.2012.07.036.

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22

Lin, Riqiang, Jiaming Zhang, Wen Gao, et al. "A Miniature Multi-Functional Photoacoustic Probe." Micromachines 14, no. 6 (2023): 1269. http://dx.doi.org/10.3390/mi14061269.

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Photoacoustic technology is a promising tool to provide morphological and functional information in biomedical research. To enhance the imaging efficiency, the reported photoacoustic probes have been designed coaxially involving complicated optical/acoustic prisms to bypass the opaque piezoelectric layer of ultrasound transducers, but this has led to bulky probes and has hindered the applications in limited space. Though the emergence of transparent piezoelectric materials helps to save effort on the coaxial design, the reported transparent ultrasound transducers were still bulky. In this work

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23

Solomatina, A. A., L. M. Mikhaleva, M. Yu Tyumentseva, et al. "Morphological and functional features of the endometrium in patients before and after ovary-sparing surgery for benign ovarian tumors." Voprosy ginekologii, akušerstva i perinatologii 21, no. 3 (2022): 45–52. http://dx.doi.org/10.20953/1726-1678-2022-3-45-52.

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Benign ovarian tumors (BOT) have a significant impact on fertility and are associated with infertility, which, in turn, relates to endometrial receptivity and depends on the ovarian status, forming the so-called endometriopathy. Objective. To study the morphological and functional features of the endometrium in patients of reproductive age before and after ovary-sparing surgery for BOT according to 2D and 3D ultrasounds. Patients and methods. The study included 145 patients who underwent surgery for BOT. Patients were divided into two groups. Group 1 included 75 patients with diminished ovaria

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Alhakami, Anas Mohammed, Reem Abdullah Babkair, Ahmad Sahely, and Shibili Nuhmani. "Effectiveness of therapeutic ultrasound on reducing pain intensity and functional disability in patients with plantar fasciitis: a systematic review of randomised controlled trials." PeerJ 12 (March 22, 2024): e17147. http://dx.doi.org/10.7717/peerj.17147.

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Background Ultrasound therapy is one of the preferred conservative treatments for patients with plantar fasciitis. This study aims to evaluate the effectiveness of therapeutic ultrasound in decreasing pain intensity and improving functional disability in patients with plantar fasciitis. Methods Five randomised control trials (RCT) were selected based on an electronic search in PubMed, Trip Database and PEDro. To be included in the systematic review, the study should be an RCT which investigated the effectiveness of therapeutic ultrasound conducted in patients with plantar fasciitis with pain i

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Ferronato, Letícia, Hemily Marega Cunha, Pâmela Maiara Machado, Gabriela dos Santos de Souza, Mirieli Denardi Limana, and Núbia Carelli Pereira de Avelar. "Phisical modalities on the functional performance in knee osteoarthritis: a sytematic review." Fisioterapia em Movimento 30, no. 3 (2017): 607–23. http://dx.doi.org/10.1590/1980-5918.030.003.ar02.

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Abstract Introduction: Despite recent advances in the treatment of osteoarthritis (OA), few studies have evaluated the longitudinal effect of physical modalities in functional capacity in patients with knee OA. Thereby, since the physical components and pain can affect the functional performance of daily activities, the effect of these treatment’s form is still to be established. Objective: Evaluate the effectiveness of therapeutic ultrasound, electrical stimulation and phototherapy in the functional performance, in patients with knee osteoarthritis. Methods: Articles present in the PubMed, Li

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26

Arief Efendi and Nurul Halimah. "THE EFFECT OF COMBINED ULTRASOUND AND MC KENZIE ON IMPROVING FUNCTIONAL ABILITY IN PATIENTS WITH MYOGENIC LOW BACK PAIN." STAND : Journal Sports Teaching and Development 4, no. 1 (2023): 68–72. http://dx.doi.org/10.36456/j-stand.v4i1.7785.

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Low back pain is a musculoskeletal disorder with signs of pain in the area around the lower back, the incidence is mostly myogenic low back pain, it increases with age. Physiotherapy interventions used to improve functional ability with a combination of ultrasound and mc kenzie. The purpose of this study was to determine the effect of a combination of ultrasound and mc kenzie on improving functional abilities in patients with myogenic low back pain. This research design uses a type of quasi-experimental with a one group pretest and posttest approach, this study has 20 respondents using a sampl

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27

Zhang, Junhang, Chen Gong, Zihan Yang, et al. "Ultrasound Flow Imaging Study on Rat Brain with Ultrasound and Light Stimulations." Bioengineering 11, no. 2 (2024): 174. http://dx.doi.org/10.3390/bioengineering11020174.

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Functional ultrasound (fUS) flow imaging provides a non-invasive method for the in vivo study of cerebral blood flow and neural activity. This study used functional flow imaging to investigate rat brain’s response to ultrasound and colored-light stimuli. Male Long-Evan rats were exposed to direct full-field strobe flashes light and ultrasound stimulation to their retinas, while brain activity was measured using high-frequency ultrasound imaging. Our study found that light stimuli, particularly blue light, elicited strong responses in the visual cortex and lateral geniculate nucleus (LGN), as e

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28

Криштопова, М. А., Л. Г. Петрова, and В. Н. Гирса. "The Method of Ultrasound Biofeedback in the Treatment of Persistent Forms of Functional Dysphonia." Оториноларингология. Восточная Европа, no. 2 (July 16, 2020): 130–40. http://dx.doi.org/10.34883/pi.2020.2.2.009.

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Цель исследования. Повысить эффективность комплексного лечения пациентов с функциональными дисфониями методом визуальной ультразвуковой биологической обратной связи.Материалы и методы. Проспективное обсервационное исследование проводилось пациентам с функциональной дисфонией/афонией (n=91). Основными видами лечения были комплексное медикаментозное лечение и фонопедия (G1, n=45) или комплексное медикаментозное лечение и фонопедия с методом ультразвуковой биологической обратной связи (G2, n=46).Результаты. Более быстрое и стойкое восстановление голоса наблюдалось в группе пациентов, получавших к

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29

Silișteanu, Andrei-Emanuel, and Juliánna Szakács. "Study on the effects of the use of therapeutic ultrasound in the treatment of osteoarticular diseases." Balneo and PRM Research Journal, Vol.13, no.1 (March 19, 2022): 482. http://dx.doi.org/10.12680/balneo.2022.482.

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Introduction. The use of therapeutic ultrasounds is a method that proved its efficiency in articu-lar and periarticular pathology, in the subacute and chronic stages. The biological effects of the ultrasound use are determined by their interaction with the cellular structures whereas the re-sults depend on the used parameters. The purpose of the survey is to evaluate / identify the ef-fects of using ultrasounds in the treatment of musculoskeletal conditions (lumbar discopathy), knee osteoarthritis). Material and method. The survey was conducted on an outpatient basis in a period of 7 months an

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30

Kenny, Jon-Émile S. "Functional Hemodynamic Monitoring With a Wireless Ultrasound Patch." Journal of Cardiothoracic and Vascular Anesthesia 35, no. 5 (2021): 1509–15. http://dx.doi.org/10.1053/j.jvca.2021.01.040.

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31

Sieu, Lim-Anna, Antoine Bergel, Elodie Tiran, et al. "EEG and functional ultrasound imaging in mobile rats." Nature Methods 12, no. 9 (2015): 831–34. http://dx.doi.org/10.1038/nmeth.3506.

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32

Bzyl, Jessica, Wiltrud Lederle, Moritz Palmowski, and Fabian Kiessling. "Molecular and functional ultrasound imaging of breast tumors." European Journal of Radiology 81 (September 2012): S11—S12. http://dx.doi.org/10.1016/s0720-048x(12)70005-0.

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33

Mourad, Pierre D., Daniel A. Lazar, Francesco P. Curra, et al. "Ultrasound Accelerates Functional Recovery after Peripheral Nerve Damage." Neurosurgery 48, no. 5 (2001): 1136–41. http://dx.doi.org/10.1227/00006123-200105000-00035.

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34

van Raaij, Martijn E., Liis Lindvere, Adrienne Dorr, et al. "Functional micro-ultrasound imaging of rodent cerebral hemodynamics." NeuroImage 58, no. 1 (2011): 100–108. http://dx.doi.org/10.1016/j.neuroimage.2011.05.088.

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35

Suzuki, A. H., J. Lee, S. G. Padilla, and S. Martini. "Altering Functional Properties of Fats Using Power Ultrasound." Journal of Food Science 75, no. 4 (2010): E208—E214. http://dx.doi.org/10.1111/j.1750-3841.2010.01572.x.

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36

Pulkkinen, Aki, Beat Werner, Ernst Martin, and Kullervo Hynynen. "Numerical simulations of clinical focused ultrasound functional neurosurgery." Physics in Medicine and Biology 59, no. 7 (2014): 1679–700. http://dx.doi.org/10.1088/0031-9155/59/7/1679.

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37

Anguluan, E., E. Kim, and J. Kim. "Modulating brain functional connectivity using transcranial ultrasound stimulation." Brain Stimulation 12, no. 2 (2019): 566–67. http://dx.doi.org/10.1016/j.brs.2018.12.877.

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38

Martin, Ernst, Daniel Jeanmonod, Anne Morel, Eyal Zadicario, and Beat Werner. "High-intensity focused ultrasound for noninvasive functional neurosurgery." Annals of Neurology 66, no. 6 (2009): 858–61. http://dx.doi.org/10.1002/ana.21801.

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39

Oppersma, Eline, Nima Hatam, Jonne Doorduin, et al. "Functional assessment of the diaphragm by speckle tracking ultrasound during inspiratory loading." Journal of Applied Physiology 123, no. 5 (2017): 1063–70. http://dx.doi.org/10.1152/japplphysiol.00095.2017.

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Assessment of diaphragmatic effort is challenging, especially in critically ill patients in the phase of weaning. Fractional thickening during inspiration assessed by ultrasound has been used to estimate diaphragm effort. It is unknown whether more sophisticated ultrasound techniques such as speckle tracking are superior in the quantification of inspiratory effort. This study evaluates the validity of speckle tracking ultrasound to quantify diaphragm contractility. Thirteen healthy volunteers underwent a randomized stepwise threshold loading protocol of 0–50% of the maximal inspiratory pressur

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Akram, Saba, Aasma Ashraf, Zainab Zahur, Aniqua Saleem, Safia Ashraf, and Nadia Nazir. "Characteristics of Ovarian Cysts Observed in Doppler Ultrasound." Pakistan Journal of Medical and Health Sciences 15, no. 10 (2021): 3304–6. http://dx.doi.org/10.53350/pjmhs2115103304.

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Background: Ovarian cysts known as ovarian masses, are commonly found incidentally in asymptomatic women. Ovarian cancer is the 7th most frequent cancer in women worldwide, as well as the eighth leading cause of cancer death. Ultrasonography is the principal imaging technique for confirming the mass ovarian origin and determining whether the mass is benign or malignant. Method: This descriptive cross sectional study was conducted from 15 June to December 2019 in the Radiology Department of Avicenna Medical College. A total of 90 ultrasounds undertaken at the Gynecological Ultrasound Unit. A to

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41

Hou, Riying. "Postoperative Nursing and Functional Rehabilitation of Ultrasound Diagnosis of Lower Rotator Cuff Injury." Scanning 2022 (August 28, 2022): 1–7. http://dx.doi.org/10.1155/2022/8319082.

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In order to explore the postoperative nursing effect and functional rehabilitation of rotator cuff repair under ultrasound diagnosis, a method of nursing and rehabilitation functional training for athletes’ wrist injury under the assistance of microscopic B-ultrasound was proposed. This study retrospectively analyzed the therapeutic effect of tendon anastomosis in 237 patients with wrist tendon injury, adopted nursing measures such as health education and functional exercise, and observed its clinical effect. The results showed that after 3-6 months of follow-up, all patients had satisfactory

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Rakan Saleh Alkhalifah. "Ultrasound Technology And Biomaterials For Precise Drug Therapy." Journal of Namibian Studies : History Politics Culture 33 (January 15, 2023): 1–11. http://dx.doi.org/10.59670/rj2ega72.

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Advanced ultrasound technology and functional biomaterials can be used to achieve precision drug therapy in different aspects such as dose, space, and/or time. At present, many physical or chemical technologies and preparations, such as ultrasound, light, magnetism, and enzyme, have been used to prepare a variety of functional biomaterials and trigger precise drug delivery. Notably, ultrasound provides a convenient and robust technology for drug triggering and precision therapy and is increasingly being studied and applied. At present, the ultrasound system mainly triggers and realizes precise

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Wibawa, Ari, Ni Wayan Tianing, Gede Parta Kinandana, and Ni Komang AYu Juniantari. "THE COMPARISON OF INTERVENTION OF ULTRASOUND AND MUSCLE ENERGY TECHNIQUE WITH ULTRASOUND AND MCKENZIE EXERCISE INTERVENTION ON INCREASING FUNCTIONAL ABILITY IN NON-SPECIFIC LOW BACK PAIN." Majalah Ilmiah Fisioterapi Indonesia 6, no. 2 (2018): 55. http://dx.doi.org/10.24843/mifi.2018.v06.i02.p13.

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This study aims to compare ultrasound interventions and muscle energy techniques more effective than ultrasound and McKenzie exercise in improving functional ability in non-specific low back pain cases. The test used is a modified oswestry low back pain disability questionnaire to measure functional pain. Using experimental design with pre-test and post-test group design involved a sample of 32 people divided into 2 groups. Group 1 with ultrasound treatment and muscle energy technique and group 2 with ultrasound treatment and Mckenzie exercise. Hypothesis test results using the independent sam

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Moser, David, Eyal Zadicario, Gilat Schiff, and Daniel Jeanmonod. "Measurement of targeting accuracy in focused ultrasound functional neurosurgery." Neurosurgical Focus 32, no. 1 (2012): E2. http://dx.doi.org/10.3171/2011.10.focus11246.

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The object of this study was to describe a method of measuring targeting accuracy in functional neurosurgery using MR imaging and the Stereotactic Atlas of the Human Thalamus and Basal Ganglia. This method should be useful for any functional procedure using these tools or similar ones, and is described here in the specific context of focused ultrasound surgery. The authors describe the atlas coordinate system used, the different relevant targeting and accuracy definitions, the tools used, the intraoperative target determination, the postoperative target reconstructions, and the calculation of

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Povanda, Bernard, Nicholas Rodio, and Joshua Prall. "Treatment of Proximal Hamstring Tendinopathy in a Runner Using Ultrasound-Guided Needle Tenotomy: A Case Report." Journal of Clinical Electrophysiology and Wound Management 3, no. 1 (2025): 25–32. https://doi.org/10.55566/jcewm-d-24-00006.

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Background To date, there has not been a case report utilizing ultrasound-guided needle tenotomy (NT) for proximal hamstring tendinopathy (PHT). This case report’s purpose was to describe the effects of ultrasound-guided NT with eccentric training and PRP injections for the treatment of PHT of a runner. Case Presentation The patient was a 58-year-old female presenting with a partial tear of the right proximal hamstring tendon diagnosed by diagnostic ultrasound. After limited improvement from initial PRP injections with an orthopedic surgeon in November of 2013, the patient was then re-evaluate

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Arik Kibar, Emine Aytunga, and Özlem Aslan. "Ultrasound-Assisted Extraction of Chickpea Proteins and Their Functional and Technological Properties." Food Technology and Biotechnology 62, no. 4 (2024): 488–500. https://doi.org/10.17113/ftb.62.04.24.8502.

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Research background. Chickpea is a very good source of protein for the development of protein-enriched plant-based ingredients. Chickpea protein isolates are primarily obtained by wet extraction methods such as alkaline or salt extraction. The energy input required for the production of chickpea protein isolates can have an impact on both the environment and processing, thus affecting nutritional quality and human health. Therefore, further research is needed to develop mild processing techniques for the isolation of chickpea proteins. Experimental approach. In this study, with the aim of deve

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47

Pinckard, Jessica, Sharon Negri, Cade A. Huston, et al. "Functional ultrasound as a quantitative approach for measuring functional hyperemia in aging models." NeuroImage 316 (August 2025): 121313. https://doi.org/10.1016/j.neuroimage.2025.121313.

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48

Ashfaq, Alweera. "Ultrasound-assisted Extraction of Plant-Based Proteins: A Novel Technique." Indian Journal of Pure & Applied Biosciences 9, no. 3 (2021): 145–50. http://dx.doi.org/10.18782/2582-2845.8676.

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Ultrasound has been explored in recent times by researchers and food processing industries due to its capacity to increase extraction efficacy by enhancing mass transfer and rupturing cells due to acoustic cavitation. In protein extraction ultrasound treatment is generally used as a pretreatment in combination with the traditional method of extraction as it breaks the cell wall and improves the extractability. Ultrasound treatment not only improves the extraction rate but can also modify the functional properties of the protein product. The rate and yield of protein extraction depend on the op

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Zhang, Minjian, Bo Li, Yafei Liu, et al. "Different Modes of Low-Frequency Focused Ultrasound-Mediated Attenuation of Epilepsy Based on the Topological Theory." Micromachines 12, no. 8 (2021): 1001. http://dx.doi.org/10.3390/mi12081001.

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Epilepsy is common brain dysfunction, where abnormal synchronized activities can be observed across multiple brain regions. Low-frequency focused pulsed ultrasound has been proven to modulate the epileptic brain network. In this study, we used two modes of low-intensity focused ultrasound (pulsed-wave and continuous-wave) to sonicate the brains of KA-induced epileptic rats, analyzed the EEG functional brain connections to explore their respective effect on the epileptic brain network, and discuss the mechanism of ultrasound neuromodulation. By comparing the brain network characteristics before

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Antsaklis, Panagiotis, and Sebija Izetbegovic. "Functional Test for Fetal Brain: The Role of KANET Test." Donald School Journal of Ultrasound in Obstetrics and Gynecology 7, no. 4 (2013): 385–99. http://dx.doi.org/10.5005/jp-journals-10009-1309.

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ABSTRACT Defining normal and abnormal fetal neurological function in utero in order to better predict antenatally which fetuses are at risk for adverse neurological outcome has remained a great challenge in perinatal medicine. Fetal behavioral patterns have been considered as indicators of fetal brain development. It has been suggested that the assessment of fetal behavior in different periods of gestation may make possible the distinction between normal and abnormal brain development. Advances in ultrasound technology and particularly the introduction of real time four-dimensional (4D) ultras

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