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Journal articles on the topic 'Fungal diagnostic'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Pendjer, I., I. Boricic, V. Arsic, et al. "Fungal sinusitis diagnostic management and classification." Acta chirurgica Iugoslavica 56, no. 3 (2009): 145–48. http://dx.doi.org/10.2298/aci0903145p.

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The aim of this paper is to present the current classification of fungal sinusitis and share our experiences in diagnostic procedures and treatment outcomes. The study includes 31 patients operated since 2000-2009. in whome some form of fungal infection had been diagnosed. There were 10 patients with mycetoma, and 16 patients with chronic non-invasive fungal sinusitis, while in five patients allergic fungal sinusitis was proven. All patients were treated postoperatively with topical steroids and irrigation with saline solution, without use of fungicides. Characteristics of chronic non-invasive

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Lane, Robin F. "Diagnostic testing for fungal diseases." Veterinary Clinics of North America: Exotic Animal Practice 6, no. 2 (2003): 301–14. http://dx.doi.org/10.1016/s1094-9194(03)00010-0.

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Skryabina, Yelena V., Yuriy S. Astakhov, Yanina S. Konenkova, et al. "Diagnosis and treatment of fungal keratitis. Part I." Ophthalmology journal 11, no. 3 (2018): 63–73. http://dx.doi.org/10.17816/ov11363-73.

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Fungal keratitis (FK) is a difficult diagnostic challenge for ophthalmologists. The aim is to familiarize practicing physicians with the diagnostic algorithm worked out in the Ophthalmological Center of SPB City hospital No. 2 using modern research methods, and to assess the epidemiology of fungal keratitis in the North-West Region. Materials and methods. Patients underwent laboratory diagnostics (fluorescence microscopy of corneal scrapings from the cornea, сulture on Sabouraud agar and broth), confocal in vivo microscopy, optical coherence tomography. Results. During the pe

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Suresh, Malavika, Maneesh Shivaputra Ganamukhi, Maneesh Shivaputra Ganamukhi, et al. "Diagnostic dilemma in a case of chronic invasive fungal sinusitis solved using a novel diagnostic test." International Journal of Otorhinolaryngology and Head and Neck Surgery 7, no. 8 (2021): 1373. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20212909.

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Fungal infections of the paranasal sinuses are a spectrum of diseases rather than one distinct entity. The prevalence of fungal sinus disease has been increasing in recent decades, especially in immunocompetent individuals. The indiscriminate use of antibiotics and immunosuppressive drugs has partially been attributed to this. The diagnosis of invasive fungal disease still imposes a challenge to medical professionals occasionally. Here we present an interesting case of a middle-aged immunocompetent male who presented to us with non-specific symptoms of chronic invasive fungal sinusitis. The ro

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Krishnan, Gayathri, Margaret Power, J. Ryan Bariola, and Ryan K. Dare. "271. Fungal Diagnostic Studies in Histoplasmosis." Open Forum Infectious Diseases 6, Supplement_2 (2019): S150. http://dx.doi.org/10.1093/ofid/ofz360.346.

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Abstract Background Histoplasmosis (histo) is a common cause of invasive fungal infection in endemic regions and accurate diagnosis is difficult without direct tissue culture or pathology. Indirect fungal antigen testing for various fungal pathogens is typically performed to assist with diagnostic workup though cross-reaction can lead to difficulty interpreting results. We aimed to evaluate the prevalence of positive antigen testing for non-Histoplasma fungal pathogens in patients with proven invasive histo. Methods We performed a retrospective review of adult patients with proven invasive his

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Thaduri, Abhinav, G. Sreekanth, Dipin Kumar Vishnuvardan, and K. Sravani Reddy. "Invasive fungal granuloma: a diagnostic challenge." International Journal of Otorhinolaryngology and Head and Neck Surgery 6, no. 8 (2020): 1529. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20203209.

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<p>Invasive fungal rhinosinusitis is a rare and life-threatening with high mortality and morbidity. Granulomatous invasive fungal rhinosinusitis has a time course exceeding 12 weeks. This disease has been reported primarily in south of Asia, however, it is very rare. When the invasive fungal sinus infection presents in a form of a granuloma with unusual presentation then they pose a diagnostic challenge to medical professionals.<strong> </strong>We present a case series of 3 cases of invasive fungal granuloma with varied presentations, which posed as a challenge in diagnosing

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Soundarya, R., H. C. Deepa, Peralam Yegneswaran Prakash, and V. Geetha. "Fungal Rhinosinusitis: An integrated diagnostic approach." Annals of Diagnostic Pathology 75 (April 2025): 152415. http://dx.doi.org/10.1016/j.anndiagpath.2024.152415.

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DESHAZO, R., and R. SWAIN. "Diagnostic criteria for allergic fungal sinusitis." Journal of Allergy and Clinical Immunology 96, no. 1 (1995): 24–35. http://dx.doi.org/10.1016/s0091-6749(95)70029-3.

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Puri, Akshjot, Michael Chesser, and Thomas Lidner. "Invasive fungal infections: A diagnostic challenge." Case Reports in Clinical Pathology 4, no. 2 (2017): 15. http://dx.doi.org/10.5430/crcp.v4n2p15.

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Introduction: Overall incidence of invasive fungal infections in solid organ transplant recipients is low with the more common infections being invasive candidiasis, aspergillosis and cryptococosis. Zygomycosis comprises of only 0.2%-1.2% of infections in renal transplant recipients with current recommendations advising against routine prophylaxis.Case: The patient was a 60-year-old male with a history of renal transplant 25 years ago on immunosuppressants, chronic transplant glomerulopathy, squamous cell carcinoma post penectomy and bilateral orchiectomy 2 years ago, controlled diabetes and h

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Margo, Curtis E., and Thomas Bombardier. "The diagnostic value of fungal autofluorescence." Survey of Ophthalmology 29, no. 5 (1985): 374–76. http://dx.doi.org/10.1016/0039-6257(85)90114-6.

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Sznajder, Wojciech, Beata Jankowska-Polańska, and Wojciech Tański. "A Narrative Review of Fungal Periprosthetic Joint Infections of the Hip and Knee: Risk Factors, Microbiological Profiles, and Treatment Challenges." Journal of Clinical Medicine 14, no. 1 (2025): 206. https://doi.org/10.3390/jcm14010206.

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Fungal periprosthetic joint infections (PJIs) are rare but increasingly recognized complications following total joint arthroplasty (TJA). While Candida albicans remains the most common pathogen, non-albicans Candida species and other fungi, such as Aspergillus, have gained prominence. These infections often present with subtle clinical features and affect patients with significant comorbidities or immunosuppression. Compared to bacterial PJIs, fungal infections pose unique diagnostic and therapeutic challenges, including biofilm formation, limited antifungal susceptibility, and protracted tre

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Thangaraja, Anusha, Veena Ramaswamy, Tejaswini B N, Sowmya B Uthaiah, and Gaurav Medikeri. "Diagnostic Accuracy of Frozen Section in Post COVID Fungal Infections." International Journal of Science and Research (IJSR) 11, no. 8 (2022): 270–73. http://dx.doi.org/10.21275/sr22803112737.

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K Suchit Roy, Lakshmi. "Isolated Fungal Ball of the Frontal Sinus - A Diagnostic Dilemma." International Journal of Science and Research (IJSR) 12, no. 6 (2023): 855–57. http://dx.doi.org/10.21275/sr23606160559.

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K. Hussain, Khalil, Dhara Malavia, Elizabeth M. Johnson, et al. "Biosensors and Diagnostics for Fungal Detection." Journal of Fungi 6, no. 4 (2020): 349. http://dx.doi.org/10.3390/jof6040349.

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Early detection is critical to the successful treatment of life-threatening infections caused by fungal pathogens, as late diagnosis of systemic infection almost always equates with a poor prognosis. The field of fungal diagnostics has some tests that are relatively simple, rapid to perform and are potentially suitable at the point of care. However, there are also more complex high-technology methodologies that offer new opportunities regarding the scale and precision of fungal diagnosis, but may be more limited in their portability and affordability. Future developments in this field are incr

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Barbui, Anna Maria, Corrado Girmenia, and Giorgio Limerutti. "Diagnosis of invasive fungal infections." Reviews in Health Care 3, no. 1S (2012): 15. http://dx.doi.org/10.7175/rhc.42931s15-25.

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A proper diagnostic strategy of invasive fungal infections (IFI) is a very important component in the management of infectious complications in hematological patients. A good diagnostic approach should be adapted to the patient in relation to the underlying disease, stage of disease, localization of infection and immune status. None of the diagnostic markers can be entirely adopted for medical decision making, and sometimes it’s useful to use the combination of several microbiological tests.The diagnosis of IFI must therefore have a multidisciplinary approach that includes clinical suspicion,

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Barbui, Anna Maria, Corrado Girmenia, and Giorgio Limerutti. "Diagnosis of invasive fungal infections." Reviews in Health Care 3, no. 1S (2012): 15–25. http://dx.doi.org/10.7175/rhc.v3i1s.429.

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A proper diagnostic strategy of invasive fungal infections (IFI) is a very important component in the management of infectious complications in hematological patients. A good diagnostic approach should be adapted to the patient in relation to the underlying disease, stage of disease, localization of infection and immune status. None of the diagnostic markers can be entirely adopted for medical decision making, and sometimes it’s useful to use the combination of several microbiological tests.The diagnosis of IFI must therefore have a multidisciplinary approach that includes clinical suspicion,

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Alfouzan, Wadha, Faten Al-Wathiqi, Haya Altawalah, Mohammad Asadzadeh, Ziauddin Khan, and David W. Denning. "Human Fungal Infections in Kuwait—Burden and Diagnostic Gaps." Journal of Fungi 6, no. 4 (2020): 306. http://dx.doi.org/10.3390/jof6040306.

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Fungal infections are an increasingly important public health issue, yet accurate statistics on fungal burden worldwide and in Kuwait are scarce. Here we estimate the incidence and prevalence of fungal infections in Kuwait. Population statistics from 2018 collected by the Public Authority for Civil Information were used, as well as data from the Ministry of Health. A literature search for Kuwait data on mycotic diseases and population at risk (chronic obstructive pulmonary disease, HIV infection/AIDS, cancer, and transplant patients) was conducted. The population in 2018 was estimated at 4,226

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Raut, Prasanna P., Sarala Menon, and Ameeta A. Joshi. "Diagnostic utility of skin prick test in fungal asthma." International Journal of Research in Medical Sciences 11, no. 6 (2023): 2108–12. http://dx.doi.org/10.18203/2320-6012.ijrms20231626.

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Background: Allergic bronchopulmonary mycosis (ABPM) is a clinical syndrome associated with immune sensitivity to various fungi. Aspergillus spp. predominates in colonizing the airways of asthmatics. Early and accurate identification of fungus in such cases can prevent worsening of asthma. Also, can help in retarding the progression of ABPM. Objectives of this study were to evaluate different fungal allergens associated with clinically diagnosed Asthma patients by Skin Prick testing (SPT), to study total IgE in asthmatic patients by serological testing and to characterize the fungal isolate as

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Meyer, Wieland, Laszlo Irinyi, Minh Thuy Vi Hoang та ін. "Database establishment for the secondary fungal DNA barcodetranslational elongation factor 1α(TEF1α)". Genome 62, № 3 (2019): 160–69. http://dx.doi.org/10.1139/gen-2018-0083.

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With new or emerging fungal infections, human and animal fungal pathogens are a growing threat worldwide. Current diagnostic tools are slow, non-specific at the species and subspecies levels, and require specific morphological expertise to accurately identify pathogens from pure cultures. DNA barcodes are easily amplified, universal, short species-specific DNA sequences, which enable rapid identification by comparison with a well-curated reference sequence collection. The primary fungal DNA barcode, ITS region, was introduced in 2012 and is now routinely used in diagnostic laboratories. Howeve

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Gudisa, Rajendra, Ritika Harchand, and Shivaprakash M. Rudramurthy. "Nucleic-Acid-Based Molecular Fungal Diagnostics: A Way to a Better Future." Diagnostics 14, no. 5 (2024): 520. http://dx.doi.org/10.3390/diagnostics14050520.

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The world has seen a tremendous increase in the number of fungal infections during the past two decades. Recently, the World Health Organisation released the pathogen priority list for fungal infections, signifying the importance of these infections in the fields of research and public health. Microbiology laboratories demand an upgrade in the diagnostic system to keep up with the increased burden of these infections. Diagnosis of fungal infections using conventional techniques has always faced limitations in terms of specificity, sensitivity, and turnaround time. Although these methods are th

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Jia, Dan Tong, and Kiran Thakur. "Fungal Infections of the Central Nervous System." Seminars in Neurology 39, no. 03 (2019): 343–57. http://dx.doi.org/10.1055/s-0039-1688916.

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Fungal central nervous system infections present in a myriad of clinical manifestation and remain a significant diagnostic challenge. Presenting symptoms, cerebrospinal fluid analysis, conventional fungal serum markers and imaging correlates of disease are seldom sensitive or specific; fungal culture growth or histopathologic analysis are often required for definitive diagnoses but limited by feasibility. Novel diagnostic tools (such as the cryptococcal antigen and next-generation sequencing) have increased diagnostic potency when available but require further studies to define their utility.I

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Uri, N., O. Ronen, T. Marshak, O. Parpara, M. Nashashibi, and M. Gruber. "Allergic fungal sinusitis and eosinophilic mucin rhinosinusitis: diagnostic criteria." Journal of Laryngology & Otology 127, no. 9 (2013): 867–71. http://dx.doi.org/10.1017/s0022215113001680.

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AbstractBackground:Chronic sinusitis is one of the most common otolaryngological diagnoses. Allergic fungal sinusitis and eosinophilic mucin rhinosinusitis can easily be misdiagnosed and treated as chronic sinusitis, causing continuing harm.Aim:To better identify and characterise these two subgroups of patients, who may suffer from a systemic disease requiring multidisciplinary treatment and prolonged follow up.Methods:A retrospective, longitudinal study of all patients diagnosed with allergic fungal sinusitis or eosinophilic mucin rhinosinusitis within one otolaryngology department over a 15-

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Lund, V. J., G. Lloyd, L. Savy, and D. Howard. "Fungal rhinosinusitis." Journal of Laryngology & Otology 114, no. 1 (2000): 76–80. http://dx.doi.org/10.1258/0022215001903762.

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Fungal infections in both their invasive and non-invasive forms can prove difficult to diagnose. The often characteristic appearances on imaging are of great assistance. CT is the primary imaging modality and is probably more accurate than MRI in diagnostic specificity and determining the extent of bone erosion. However this may require a modified scanning technique to adequately demonstrate the typical soft tissue density variations of fungi. MRI should be used to supplement CT when intra-cranial or intra-orbital extension is suspected.

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Peggy Chang, Han-Ying, and James Chodosh. "Diagnostic and Therapeutic Considerations in Fungal Keratitis." International Ophthalmology Clinics 51, no. 4 (2011): 33–42. http://dx.doi.org/10.1097/iio.0b013e31822d64dc.

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Wheat, L. Joseph. "Nonculture diagnostic methods for invasive fungal infections." Current Infectious Disease Reports 9, no. 6 (2007): 465–71. http://dx.doi.org/10.1007/s11908-007-0071-7.

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García-Romero, Maria Teresa, Gabriela Sánchez-Cardenas, Silvia Angélica Carmona-Cruz, and Mónica Fernández-Sánchez. "Skin Fungal Infections in Children: Diagnostic Challenges." Current Fungal Infection Reports 14, no. 4 (2020): 329–47. http://dx.doi.org/10.1007/s12281-020-00407-1.

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Vyzantiadis, Timoleon-Achilleas, Eleni Gavriilaki, and Athanasios Tragiannidis. "Human Fungal Infections: Diagnostic and Therapeutic Challenges." Journal of Fungi 11, no. 1 (2025): 66. https://doi.org/10.3390/jof11010066.

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Ullah, Nadir, Ludovica Fusco, Luigi Ametrano, et al. "Diagnostic Approach to Pneumonia in Immunocompromised Hosts." Journal of Clinical Medicine 14, no. 2 (2025): 389. https://doi.org/10.3390/jcm14020389.

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In immunocompromised patients, pneumonia presents a diagnostic challenge due to diverse etiologies, nonspecific symptoms, overlapping radiological presentation, frequent co-infections, and the potential for rapid progression to severe disease. Thus, timely and accurate diagnosis of all pathogens is crucial. This narrative review explores the latest advancements in microbiological diagnostic techniques for pneumonia in immunocompromised patients. It covers major available microbiological tools for diagnosing both community-acquired and hospital-acquired pneumonia, encompassing a wide spectrum o

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Ivagnes, Vittorio, Elena De Carolis, Carlotta Magrì, Riccardo Torelli, Brunella Posteraro, and Maurizio Sanguinetti. "Advancing Dermatomycosis Diagnosis: Evaluating a Microarray-Based Platform for Rapid and Accurate Fungal Detection—A Pilot Study." Journal of Fungi 11, no. 3 (2025): 234. https://doi.org/10.3390/jof11030234.

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Dermatomycosis, including the most prevalent onychomycosis, significantly impacts patients’ quality of life due to its chronic nature and high recurrence rate. Conventional diagnostic methods are often limited by low sensitivity and specificity and prolonged turnaround times. This study evaluates the EUROArray Dermatomycosis Platform, a microarray-based molecular assay, for its performance in identifying fungi causing dermatomycosis. Forty reference fungal strains, covering on-panel and off-panel species, and 120 clinical samples from patients with suspected dermatomycosis were analyzed. The p

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Aziz, Mubashrah, Sadia Mailk, Muniba Manzoor, Sadaf Aziz, Munazzah Aziz, and Muzammil Manzoor. "Diagnosis of Fungal Sinusitis; Is Fungal Culture a Must?" Pakistan Armed Forces Medical Journal 73, no. 2 (2023): 418–21. http://dx.doi.org/10.51253/pafmj.v73i2.8188.

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Objective: To determine the diagnostic accuracy of computed tomography (CT) of paranasal sinuses (PNS) in detecting fungal sinusitis keeping fungal culture as the gold standard. Study Design: Cross-sectional validation study. Place and Duration of Study: Department of Radiology, Combined Military Hospital, Rawalpindi Pakistan, from Jun 2018 to Jun 2019. Methodology: A total of 323 patients of either gender were included in the study (aged from 10-70 years). All the patients underwent plain CT scans of paranasal sinuses, and the CT scan findings were reported and recorded on p

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ALTUN, Ece, Elif KUZUCULAR, and Ayşe İstanbullu TOSUN. "Comparison of diagnostic methods in onychomycosis." Journal of Health Sciences and Medicine 6, no. 2 (2023): 353–58. http://dx.doi.org/10.32322/jhsm.1204419.

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Aim: Onychomycosis is a chronic fungal infection of the nail bed, plate, or matrix. This study aimed to compare the sensitivity of three diagnostic methods in the diagnosis of onychomycosis. Material and Method: This study included 39 patients with a clinical diagnosis of onychomycosis of the toenails, who presented to Medipol Mega University Hospital between May 2019 and August 2022. Using the nail samples taken from the patients, the results of the direct microscopic examination with standard potassium hydroxide (KOH), histopathological examination performed with periodic acid-Schiff (

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Smith, Dallas J., Jeremy A. W. Gold, Kaitlin Benedict, et al. "Public Health Research Priorities for Fungal Diseases: A Multidisciplinary Approach to Save Lives." Journal of Fungi 9, no. 8 (2023): 820. http://dx.doi.org/10.3390/jof9080820.

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Fungal infections can cause severe disease and death and impose a substantial economic burden on healthcare systems. Public health research requires a multidisciplinary approach and is essential to help save lives and prevent disability from fungal diseases. In this manuscript, we outline the main public health research priorities for fungal diseases, including the measurement of the fungal disease burden and distribution and the need for improved diagnostics, therapeutics, and vaccines. Characterizing the public health, economic, health system, and individual burden caused by fungal diseases

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Costales, Cristina R., Susan Butler-Wu, and Rosemary She. "739. A Two-Center Assessment of Histopathologic Diagnostic Performance for Fungal Organism Identification." Open Forum Infectious Diseases 7, Supplement_1 (2020): S419. http://dx.doi.org/10.1093/ofid/ofaa439.930.

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Abstract Background Accurate detection and identification of invasive fungal pathogens relies on concordance of several complementary laboratory techniques, including fungal culture, serology, and histopathologic identification. Histopathologic stains such as the Gomori methenamine silver stain (GMS) are used to highlight fungal cell wall in tissue specimens. We sought to determine the diagnostic performance of histopathology fungal stains as compared to fungal culture for diagnosis of invasive fungal tissue infection at tertiary medical centers with dissimilar patient populations. Methods We

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Chaitanya, Krishna V., and Lakshmi C. Kalavathi. "Evaluation of Diagnostic Criteria for AFRS: A Hospital Based Study." Bengal Journal of Otolaryngology and Head Neck Surgery 25, no. 3 (2017): 130–35. http://dx.doi.org/10.47210/bjohns.2017.v25i3.133.

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Introduction Bent and Kuhn criteria are the most commonly accepted diagnostic criteria for diagnosis of Allergic Fungal Rhinosinusitis. Other diagnostic criteria for the diagnosis of Allergic Fungal Rhinosinusitis include unilateral nasal disease, Charcot Leyden crystals, bony erosions which form the minor criteria in the diagnosis of Allergic Fungal Rhinosinusitis. Clinical and Laboratory features in Allergic fungal rhinosinusitis are variable. These variations in the diagnostic criteria in the diagnosis of Allergic Fungal Rhinosinusitis have been analysed in the present study. Ma

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Camp, Iris, Gabriele Manhart, Claudia Schabereiter-Gurtner, Kathrin Spettel, Brigitte Selitsch, and Birgit Willinger. "Clinical evaluation of an in-house panfungal real-time PCR assay for the detection of fungal pathogens." Infection 48, no. 3 (2020): 345–55. http://dx.doi.org/10.1007/s15010-020-01395-7.

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Abstract Purpose Due to an increasing incidence of invasive fungal infections, the availability of reliable diagnostic tools for the fast detection of a wide spectrum of fungal pathogens is of vital importance. In this study, we aimed to conduct an extensive clinical evaluation of a recently published in-house panfungal PCR assay on samples from suspected invasive fungal infections. Methods Overall 265 clinical samples from 232 patients with suspected invasive fungal disease (96 deep airway samples, 60 sterile fluids, 50 tissue biopsies, and 59 blood samples) were included. All samples underwe

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Kennedy, Cassie C., Kelly M. Pennington, Elena Beam, and Raymund R. Razonable. "Fungal Infection in Lung Transplantation." Seminars in Respiratory and Critical Care Medicine 42, no. 03 (2021): 471–82. http://dx.doi.org/10.1055/s-0041-1729173.

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AbstractInvasive fungal infections threaten lung transplant outcomes with high associated morbidity and mortality. Pharmacologic prophylaxis may be key to prevent posttransplant invasive fungal infections, but cost, adverse effects, and absorption issues are barriers to effective prophylaxis. Trends in fungal infection diagnostic strategies utilize molecular diagnostic methodologies to complement traditional histopathology and culture techniques. While lung transplant recipients are susceptible to a variety of fungal pathogens, Candida spp. and Aspergillus spp. infections remain the most commo

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Yang, Bryant, Omai Garner, Richard Ou, and Nicholas Stanzione. "657. Diagnostic Utility of Dedicated Fungal Blood Cultures for Diagnosis of Candidemia." Open Forum Infectious Diseases 7, Supplement_1 (2020): S385. http://dx.doi.org/10.1093/ofid/ofaa439.850.

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Abstract Background Blood culture techniques have improved to the point where they are considered sensitive enough for detection of Candida. Expert guidelines clarifying the utility of use of dedicated fungal isolator cultures are lacking, and we wondered what utility, if any, they add for the diagnosis of candidemia. Methods All patients with cultures between March 2016-February 2020 positive for Candida were examined via manual chart review, noting time to positivity and time of initiation of antifungal therapy. Results We focused on cases of candidemia where a fungal culture was ordered and

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Stempak, Lisa M., Sherilynn A. Vogel, Sandra S. Richter, Robert Wyllie, and Gary W. Procop. "Routine Broad-Range Fungal Polymerase Chain Reaction With DNA Sequencing in Patients With Suspected Mycoses Does Not Add Value and Is Not Cost-Effective." Archives of Pathology & Laboratory Medicine 143, no. 5 (2018): 634–38. http://dx.doi.org/10.5858/arpa.2017-0299-oa.

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Context.— New molecular diagnostic tests regularly become available, and they may be assumed to be superior to traditional diagnostic studies. The added cost of these studies should be considered in conjunction with the value provided for patient care. Objective.— To assess the cost and diagnostic value of broad-range polymerase chain reaction (PCR) and DNA sequencing for the diagnosis of fungal infections compared with traditional studies. Design.— We reviewed the cost and clinical impact of broad-range fungal PCR/DNA sequencing for 65 specimens for which this test, a direct fungal examinatio

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Hammarström, Helena, Jesper Magnusson, Anna Stjärne Aspelund, et al. "Fungal Tracheobronchitis in Lung Transplant Recipients: Incidence and Utility of Diagnostic Markers." Journal of Fungi 9, no. 1 (2022): 3. http://dx.doi.org/10.3390/jof9010003.

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Fungal tracheobronchitis caused by Aspergillus and Candida spp. is a recognized complication after lung transplantation, but knowledge of the incidence of Candida tracheobronchitis is lacking. The diagnosis relies on fungal cultures in bronchoalveolar lavage fluid (BALF), but cultures have low specificity. We aimed to evaluate the one-year incidence of fungal tracheobronchitis after lung transplantation and to assess the utility of diagnostic markers in serum and BALF to discriminate fungal tracheobronchitis from colonization. Ninety-seven consecutively included adult lung-transplant recipient

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Cho, Sung-Woo, Won-Wook Lee, Dae Ma, et al. "Orbital Apex Lesions: A Diagnostic and Therapeutic Challenge." Journal of Neurological Surgery Part B: Skull Base 79, no. 04 (2017): 386–93. http://dx.doi.org/10.1055/s-0037-1612616.

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Objective To analyze the clinical characteristics of and treatment outcomes for orbital apex lesions according to their pathological diagnosis and identify clinical characteristics that could aid in their differential diagnosis. Design Retrospective analysis design was used for this study. Setting The study was conducted in a single tertiary institution. Participants Patients with pathologically confirmed lesions centered in the orbital apex who were admitted between January 2011 and December 2015. Main Outcome Measures Clinical characteristics, including demographics, predisposing factors, pr

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Reveglia, Pierluigi, Carmela Paolillo, and Gaetano Corso. "The Significance of Fungal Specialized Metabolites in One Health Perspectives." International Journal of Molecular Sciences 26, no. 7 (2025): 3120. https://doi.org/10.3390/ijms26073120.

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Among the emerging threats in global health, fungal pathogens stand out as some of the most important, causing over 1.6 million deaths annually and destroying a third of all food crops each year, exacerbating food insecurity and economic losses. Climate change further amplifies the threat by enabling pathogenic fungi to survive at mammalian temperatures, increasing risks of zoonotic transmission and antifungal resistance. In this context, interdisciplinary research, particularly the One Health approach, is crucial for understanding the evolution of fungal resistance and improving diagnostic an

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Abu Talib, Dian Nadia, Meng Hsien Yong, Rona Asnida Nasaruddin, Jemaima Che-Hamzah, and Mae-Lynn Catherine Bastion. "Chronic endogenous fungal endophthalmitis: diagnostic and treatment challenges." Medicine 100, no. 14 (2021): e25459. http://dx.doi.org/10.1097/md.0000000000025459.

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Castagnola, Elio. "Clinical and diagnostic pathways in pediatric fungal infections." Reviews in Health Care 4, no. 1S (2013): 19–26. http://dx.doi.org/10.7175/rhc.v4i1s.859.

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Generally speaking, in pediatrics the patients mostly affected by fungal infections are hematological patients, followed by those with solid tumors, and transplant recipients. Candida infections generally occur just after birth, whereas Aspergillus infections are age-related, and increase their incidence with age. However, among infections, the incidence of bacteremias are still greater than that of mycoses. In pediatrics, in Italy the immunocompromised patients – thus particularly susceptible to fungal infections – are mainly those with severe combined immunodeficiency, chronic mucocutaneous

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Procop, Gary W. "Evaluation of Molecular Diagnostic Assays for Fungal Infections." Journal of Molecular Diagnostics 8, no. 3 (2006): 297–98. http://dx.doi.org/10.2353/jmoldx.2006.060066.

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Idriss, Munir H., Ahmed Khalil, and Dirk Elston. "The diagnostic value of fungal fluorescence in onychomycosis." Journal of Cutaneous Pathology 40, no. 4 (2013): 385–90. http://dx.doi.org/10.1111/cup.12086.

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Smith, Eric M., Steven D. Hart, and Ashley E. Kita. "Allergic fungal sinusitis mimicking mycetoma: A diagnostic challenge." Otolaryngology Case Reports 34 (March 2025): 100639. https://doi.org/10.1016/j.xocr.2024.100639.

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de Pauw, B. E. "Fungal infections: diagnostic problems and choice of therapy." Leukemia Supplements 1, S2 (2012): S22—S23. http://dx.doi.org/10.1038/leusup.2012.14.

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Katragkou, Aspasia, Brian T. Fisher, Andreas H. Groll, Emmanuel Roilides, and Thomas J. Walsh. "Diagnostic Imaging and Invasive Fungal Diseases in Children." Journal of the Pediatric Infectious Diseases Society 6, suppl_1 (2017): S22—S31. http://dx.doi.org/10.1093/jpids/pix055.

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Sham, S., A. Bendari, H. Hosseini, D. Otero Espinal, O. Vele, and S. Duong. "Filamentous Bacteria Resembling Fungal Hyphae: A Diagnostic Pitfall." American Journal of Clinical Pathology 158, Supplement_1 (2022): S139. http://dx.doi.org/10.1093/ajcp/aqac126.295.

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Abstract Introduction/Objective When exposed to antibiotics or a host immune response, Gram-negative bacilli grow with inhibited septation producing long continuous cells; a phenomenon known as filamentation. Methods/Case Report We present a case of a 68-year-old man with quadriplegia, which was caused by the right vertebral artery dissection and subarachnoid hemorrhage requiring an emergent posterior inferior cerebellar artery direct bypass surgery. Lung lower lobe infiltrates were noted 3 days after the surgery. A bronchial wash culture was negative for growth, and a sputum specimen grew Ser

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Whitney, Beth L., John Broussard, and Joseph D. Stefanacci. "Four cats with fungal rhinitis." Journal of Feline Medicine and Surgery 7, no. 1 (2005): 53–58. http://dx.doi.org/10.1016/j.jfms.2004.02.004.

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Fungal rhinitis is uncommon in the cat and cases of nasal aspergillosis–penicilliosis have been rarely reported. Signs of fungal rhinitis include epistaxis, sneezing, mucopurulent nasal discharge and exophthalmous. Brachycephalic feline breeds seem to be at increased risk for development of nasal aspergillosis–penicilliosis. Computed tomography (CT) imaging and rhinoscopy are useful in assessing the extent of the disease and in obtaining diagnostic samples. Fungal culture may lead to false negative or positive results and must be used in conjunction with other diagnostic tests. Serological tes

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