Log in

Relevant bibliographies by topics / Furan derivatives / Journal articles

To see the other types of publications on this topic, follow the link: Furan derivatives.

Journal articles on the topic 'Furan derivatives'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Furan derivatives.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Duc, Dau Xuan. "Recent Achievement in the Synthesis of Benzo[b]furans." Current Organic Synthesis 17, no. 7 (2020): 498–517. http://dx.doi.org/10.2174/1570179417666200625212639.

Full text

Abstract:

Background: Benzo[b]furan derivatives are oxygen-containing heterocyclic compounds consisting of fused benzene and furan rings and are present in a large number of natural and non-natural compounds. This class of compounds has a wide spectrum of biological activities, such as antiarrhythmic, anticancer, inflammatory, antioxidant, antimicrobial, and antiviral. Furthermore, benzo[b]furan derivatives have also been applied in various areas, such as organic electroluminescence device materials and organic dyes, photosensitizing material, organic synthesis as building blocks or intermediates. : Bec

APA, Harvard, Vancouver, ISO, and other styles

2

Hana, Saeid1* Hadeel Al-sayed2 Marwa Bader2. "A Review on Biological and Medicinal Significance of Furan." Alq J Med App Sci 6, no. 1 (2023): 44–58. https://doi.org/10.5281/zenodo.7650255.

Full text

Abstract:

An important group of heterocyclic compounds with significant biological characteristics are furan derivatives. The creation of furan derivatives and their testing for various pharmacological properties have received a lot of attention over the past few decades. Various substances with anti-bacterial properties have a fundamental skeleton made up of furan rings. These molecules are frequently used in antiviral, antifungal, anti-inflammatory, analgesic, antidepressant, anti-anxiolytic, anti-parkinsonian, anti-glaucoma, muscle relaxant, antihypertensive, diuretic, anti-ulcer, anti-ageing, and an

APA, Harvard, Vancouver, ISO, and other styles

3

Albrand, Michel, René Dolmazon, and Patrick Pollet. "Synthèse, structure et études spectroscopiques RMN 1H et 13C de dérivés perhydrocyclododéca[b]furaniques." Canadian Journal of Chemistry 69, no. 3 (1991): 521–27. http://dx.doi.org/10.1139/v91-078.

Full text

Abstract:

A synthetic route to perhydrocyclododeca[b]furan-3-ols, perhydrocyclododeca[b]furan-3-ones, and perhydrocyclododeca[b]furan derivatives is described. Their configurations were determined. For the perhydrocyclododeca[b]furan-3-one and perhydrocyclododeca[b]furan pairs, the cis isomer was much less stable than the trans isomer. This agrees well with results from a conformational analysis, carried out by molecular mechanics. The 1H and l3C NMR spectra are reported. Key words: perhydrocyclododeca[b]furans, conformations, force field calculations, 1H and 13C NMR.

APA, Harvard, Vancouver, ISO, and other styles

4

Yadav, Maruti B., and Yeon Tae Jeong. "A one-pot ring-closure and ring-opening sequence for the cascade synthesis of dihydrofurofurans and functionalized furans." Organic & Biomolecular Chemistry 19, no. 34 (2021): 7409–19. http://dx.doi.org/10.1039/d1ob01300a.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Hasimujiang, Balati, Shengsheng Lin, Chengwei Zheng, Yong Zeng, and Zhixiong Ruan. "Direct Electrooxidative Selenylation/Cyclization of Alkynes: Access to Functionalized Benzo[b]furans." Molecules 27, no. 19 (2022): 6314. http://dx.doi.org/10.3390/molecules27196314.

Full text

Abstract:

A mild, practical, metal and oxidant-free methodology for the synthesis of various C-3 selenylated benzo[b]furan derivatives was developed through the intramolecular cyclization of alkynes promoted with diselenides via electrooxidation. A wide range of selenium-substituted benzo[b]furan derivatives were obtained in good to excellent yields with high regioselectivity under constant current in an undivided cell equipped with carbon and platinum plates as the anode and cathode, respectively. Moreover, the convergent approach exhibited good functional group tolerance and could be easily scaled up

APA, Harvard, Vancouver, ISO, and other styles

6

Jurášek, Adolf, Vladimír Žvak, Jaroslav Kováč, Oľga Rajniaková та Jarmila Štetinová. "Synthesis and reactions of β-substituted derivatives of furan". Collection of Czechoslovak Chemical Communications 50, № 9 (1985): 2077–83. http://dx.doi.org/10.1135/cccc19852077.

Full text

Abstract:

The 1,4-cycloaddition reaction of 4-phenyl-1,3-oxazole to 2-propinyl benzoate and dimethyl butinedioate afforded the respective 3-furylmethyl benzoate (I) and 3,4-bis(methoxycarbonyl)furan (II). These compounds served for the synthesis of 3-chloromethylfuran and 3,4-bis(chloromethyl)furan, which afforded via Wittig reaction 3-(β-arylvinyl)furans III (aryl = 5-nitro-2-furyl (IIIa), 5-nitro-2-thienyl (IIIb), 1-methyl-4-nitro-2-pyrrolyl (IIIc), and 4-nitrophenyl (IIIe)) and 3,4-bis(β-arylvinyl)furans IV (aryl = 5-nitrofuryl (IVa), 5-nitro-2-thienyl (IVc), and 4-nitrophenyl (IVd)). According to sp

APA, Harvard, Vancouver, ISO, and other styles

7

Saito, Yoshinori, Koji Takiguchi, Xun Gong, Chiaki Kuroda, and Motoo Tori. "Thiophene, Furans, and Related Aromatic Compounds from Eupatorium heterophyllum." Natural Product Communications 6, no. 3 (2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600312.

Full text

Abstract:

A thiophene, two furans, a dihydro furan, and two acetylenic benzene derivatives were isolated from the roots of Eupatorium heterophyllum collected in China. Structures were established on the basis of spectroscopic analyses as well as chemical transformations.

APA, Harvard, Vancouver, ISO, and other styles

8

Ma, Linyi, and Xuhui Jin. "Design of a novel D-A-D type furan-based charge transfer organic photoelectric material." Journal of Physics: Conference Series 2783, no. 1 (2024): 012025. http://dx.doi.org/10.1088/1742-6596/2783/1/012025.

Full text

Abstract:

Abstract This work describes the synthesis of a novel D-A-D type furan derivative using a [2+2] cycloaddition and ring-opening reaction. Compared to thiophene-based materials, furan derivatives have lower aromaticity and more quinone-like structures, resulting in better π-electron delocalization. The novel D-A-D furan molecule in this paper exhibits a reduced bandgap and enhanced absorption in the near-infrared and visible regions, as well as strong fluorescence and good solubility.

APA, Harvard, Vancouver, ISO, and other styles

9

Lasseuguette, Elsa, Alessandro Gandini, and Hans-Joachim Timpe. "Photoreactive furan derivatives." Journal of Photochemistry and Photobiology A: Chemistry 174, no. 3 (2005): 222–28. http://dx.doi.org/10.1016/j.jphotochem.2005.03.012.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Eggly, Alyssa S., Namuunzul Otgontseren, Carson B. Roberts, Amir Y. Alwali, Haylie E. Hennigan, and Elizabeth I. Parkinson. "A Diels–Alder probe for discovery of natural products containing furan moieties." Beilstein Journal of Organic Chemistry 20 (May 2, 2024): 1001–10. http://dx.doi.org/10.3762/bjoc.20.88.

Full text

Abstract:

Natural products (NPs) are fantastic sources of inspiration for novel pharmaceuticals, oftentimes showing unique bioactivity against interesting targets. Specifically, NPs containing furan moieties show activity against a variety of diseases including fungal infections, and cancers. However, it is challenging to discover and isolate these small molecules from cell supernatant. The work described herein showcases the development of a molecular probe that can covalently modify furan moieties via a [4 + 2] Diels–Alder cycloaddition, making them easily identifiable on liquid chromatography–mass sp

APA, Harvard, Vancouver, ISO, and other styles

11

Kim, Donghyeon, Jaehyun You, Da Hye Lee, Hojin Hong, Dongwook Kim, and Yoonsu Park. "Photocatalytic furan-to-pyrrole conversion." Science 386, no. 6717 (2024): 99–105. http://dx.doi.org/10.1126/science.adq6245.

Full text

Abstract:

The identity of a heteroatom within an aromatic ring influences the chemical properties of that heterocyclic compound. Systematically evaluating the effect of a single atom, however, poses synthetic challenges, primarily as a result of thermodynamic mismatches in atomic exchange processes. We present a photocatalytic strategy that swaps an oxygen atom of furan with a nitrogen group, directly converting the furan into a pyrrole analog in a single intermolecular reaction. High compatibility was observed with various furan derivatives and nitrogen nucleophiles commonly used in drug discovery, and

APA, Harvard, Vancouver, ISO, and other styles

12

Krause, T., C. Tubbesing, K. Benzing, and H. F. Schöler. "Model reactions and natural occurrence of furans from hypersaline environments." Biogeosciences Discussions 10, no. 11 (2013): 17439–68. http://dx.doi.org/10.5194/bgd-10-17439-2013.

Full text

Abstract:

Abstract. Volatile organic compounds like furan and its derivatives are important for atmospheric properties and reactions. In this paper the known abiotic formation of furan from catechol under Fenton-like conditions with Fe3+ sulphate was revised by the use of a bispidine Fe2+ complex as a~model compound for iron with well-known characteristics. While total yields were comparable to those with the Fe3+ salt, the turnover numbers of the active iron species increased. Additionally, the role of iron and pH will be discussed during furan formation from model compounds and in natural sediment and

APA, Harvard, Vancouver, ISO, and other styles

13

Nagarsha, K. M., T. M. Sharanakumar, D. Ramesh, M. N. Kumarswamy, and K. P. Latha. "SYNTHESIS, CHARACTERIZATION, AND ANTIBACTERIAL ACTIVITIES OF NAPHTHO[2,1-b]FURAN DERIVATIVES." RASAYAN Journal of Chemistry 15, no. 04 (2022): 2477–84. http://dx.doi.org/10.31788/rjc.2022.1548052.

Full text

Abstract:

The naphthofuran and its derivatives are important biological compounds so we have focused on the synthesis of naphthofuran derivatives. The synthesized compounds of ethyl 1-(acetylamino)-5-nitronaphtho[2,1-b]furan-2- carboxylate (3), and N-[2-(hydrazinylcarbonyl)-5-nitronaphtho[2,1-b]furan-1-yl]acetamide (4) used for the synthesis of N-(2-{[(2Z)-2-benzylidenehydrazinyl]carbonyl}-5-nitronaphtho[2,1-b]furan-1-yl)acetamide compounds of four derivatives 5 (a-d) and 1-acetamido-5-nitro-N-(5-oxo-2-phenylthiazolidin-3-yl)naphtha[2,1-b]furan-2-carboxamide compounds of four derivatives 6 (a-d). The pr

APA, Harvard, Vancouver, ISO, and other styles

14

Nguyen, Van Phuong, Thi Phuong Quynh Le, Nhu Da Le, et al. "Antibacterial furan derivatives from the flowers of Chrysanthemum indicum L." BioResources 20, no. 1 (2024): 1188–99. https://doi.org/10.15376/biores.20.1.1188-1199.

Full text

Abstract:

Furan derivatives are recognized for their diverse biological activities, particularly their antimicrobial properties. In this study, three new furan derivatives were isolated from acid-treated Chrysanthemum indicum flowers. The structures were elucidated using spectroscopic techniques and identified as methyl (E)-3-((5-(methoxymethyl)furan-2-yl)methylene)-4-oxopentanoate (1), methyl (Z)-3-((5-(methoxymethyl)furan-2-yl)methylene)-4-oxopentanoate (2), and methyl (E)-3-(furan-2-ylmethylene)-4-oxopentanoate (3). These compounds were evaluated for antibacterial activity against Vibrio spp. and Mic

APA, Harvard, Vancouver, ISO, and other styles

15

Phutdhawong, Weerachai, Siwaporn Inpang, Thongchai Taechowisan, and Waya S. Phutdhawong. "Synthesis and Biological Activity Studies of Methyl-5-(Hydroxymethyl)-2-Furan Carboxylate and Derivatives." Oriental Journal of Chemistry 35, no. 3 (2019): 080–1085. http://dx.doi.org/10.13005/ojc/350322.

Full text

Abstract:

Methyl-5-(hydroxymethyl)-2-furan carboxylate and derivatives were prepared from furfuryl alcohol and their biological activities were studied for cytotoxicity against cancer cell lines HeLa, HepG2 and Vero, and Gram (+) and Gram (-) bacteria. The amine derivative, (5-(((2-(1H-indol-3-yl)ethyl)amino)methyl) furan-2-yl)methyl acetate, was found to have the most potent biological activity with IC50 62.37 µg/mL against the HeLa cell line and MIC 250 µg/mL against the photogenic bacteria.

APA, Harvard, Vancouver, ISO, and other styles

16

Tarini, Dewangan Miss Pragya Patel. "PREVENTION OF DISTRIBUTION TRANSFORMER PREMATURE FAILURES." INTERNATIONAL JOURNAL OF ENGINEERING SCIENCES & RESEARCH TECHNOLOGY 6, no. 5 (2017): 289–95. https://doi.org/10.5281/zenodo.573513.

Full text

Abstract:

This paper deals with three types of Distribution Transformer failure analysis tests which can help in monitoring the Distribution Transformers condition. The three methods are Conventional oil test, Furan derivatives test, and Markov models criteria. Conventional oil testing procedures determine the gas concentrations in the Distribution Transformers oil sample and analyzing the defect by considering the ratio of two suitable gasses. Furan derivative analysis includes determination of Furan derivatives present in the Distribution Transformers oil sample and helps in deciding the Distribution

APA, Harvard, Vancouver, ISO, and other styles

17

Janczewski, Łukasz, Dariusz Zieliński, and Beata Kolesińska. "Synthesis of amides and esters containing furan rings under microwave-assisted conditions." Open Chemistry 19, no. 1 (2021): 265–80. http://dx.doi.org/10.1515/chem-2021-0034.

Full text

Abstract:

Abstract In this work, we present a novel method for the synthesis of ester and amide derivatives containing furan rings (furfural derivatives) under mild synthetic conditions supported by microwave radiation. N-(Furan-2-ylmethyl)furan-2-carboxamide and furan-2-ylmethyl furan-2-carboxylate were produced using 2-furoic acid, furfurylamine, and furfuryl alcohol. The reactions were carried out in a microwave reactor in the presence of effective coupling reagents: DMT/NMM/TsO− or EDC. The reaction time, the solvent, and the amounts of the substrates were optimized. After crystallization or flash c

APA, Harvard, Vancouver, ISO, and other styles

18

Moursounidis, John, and Dieter Wege. "Benzannulated Isobenzofurans." Australian Journal of Chemistry 41, no. 2 (1988): 235. http://dx.doi.org/10.1071/ch9880235.

Full text

Abstract:

A number of arynes, generated by treatment of haloarenes with sodium or potassium amide in tetrahydrofuran, were trapped with furan. The resulting dihydro epoxy arenes were converted into the following annulated isobenzofuran derivatives by using reverse Diels-Alder methodology: naphtho[l,2-clfuran, phenanthro[9,10-elfuran, pyreno[l,2-elfuran, pyreno[3,4- elfuran, anthra[l,2- elfuran, phenanthro[l,2- clfuran and phenanthro[3,4- elfuran. Bimolecular rate constants for the addition of maleic anhydride to these furans were measured, and were correlated with the Herndon structure count. Addition o

APA, Harvard, Vancouver, ISO, and other styles

19

Fatima, Miraj, Samina Aslam, Ansa Madeeha Zafar, et al. "Exploring the Synthetic Chemistry of Phenyl-3-(5-aryl-2-furyl)- 2-propen-1-ones as Urease Inhibitors: Mechanistic Approach through Urease Inhibition, Molecular Docking and Structure–Activity Relationship." Biomedicines 11, no. 9 (2023): 2428. http://dx.doi.org/10.3390/biomedicines11092428.

Full text

Abstract:

Furan chalcone scaffolds belong to the most privileged and promising oxygen-containing heterocyclic class of compounds, which have a wide spectrum of therapeutic applications in the field of pharmaceutics, pharmacology, and medicinal chemistry. This research described the synthesis of a series of twelve novel and seven reported furan chalcone (conventional synthetic approach) analogues 4a–s through the application of microwave-assisted synthetic methodology and evaluated for therapeutic inhibition potential against bacterial urease enzyme. In the first step, a series of nineteen substituted 5-

APA, Harvard, Vancouver, ISO, and other styles

20

Guilarte, Verónica, M. Pilar Castroviejo, Estela Álvarez, and Roberto Sanz. "Combined directed ortho-zincation and palladium-catalyzed strategies: Synthesis of 4,n-dimethoxy-substituted benzo[b]furans." Beilstein Journal of Organic Chemistry 7 (September 12, 2011): 1255–60. http://dx.doi.org/10.3762/bjoc.7.146.

Full text

Abstract:

A new route to regioselectively dialkoxy-functionalized benzo[b]furan derivatives has been developed from 3-halo-2-iodoanisoles bearing an additional methoxy group, which have been accessed through an ortho-zincation/iodination reaction. Two palladium-catalyzed processes, namely a Sonogashira coupling followed by a tandem hydroxylation/cyclization sequence, give rise to new and interesting dimethoxy-substituted benzo[b]furans.

APA, Harvard, Vancouver, ISO, and other styles

21

Krause, T., C. Tubbesing, K. Benzing, and H. F. Schöler. "Model reactions and natural occurrence of furans from hypersaline environments." Biogeosciences 11, no. 10 (2014): 2871–82. http://dx.doi.org/10.5194/bg-11-2871-2014.

Full text

Abstract:

Abstract. Volatile organic compounds like furan and its derivatives are important for atmospheric properties and reactions. In this work the known abiotic formation of furan from catechol under Fenton-like conditions with Fe3+ sulfate was revised by the use of a bispidine Fe2+ complex as a model compound for iron with well-known characteristics. While total yields were comparable to those with the Fe3+ salt, the bispidine Fe2+ complex is a better catalyst as the turnover numbers of the active iron species were higher. Additionally, the role of iron and pH is discussed in relation to furan form

APA, Harvard, Vancouver, ISO, and other styles

22

Li, Yibiao, Liang Cheng, Xiaohang Liu, Bin Li, and Ning Sun. "Copper-promoted hydration and annulation of 2-fluorophenylacetylene derivatives: from alkynes to benzo[b]furans and benzo[b]thiophenes." Beilstein Journal of Organic Chemistry 10 (December 4, 2014): 2886–91. http://dx.doi.org/10.3762/bjoc.10.305.

Full text

Abstract:

An efficient copper-promoted hydration reaction and its application in the synthesis of benzo[b]furan and benzo[b]thiophene derivatives is presented starting from readily available 2-fluorophenylacetylene derivatives. The key annulation step involves the hydration of the C–F bond of 2-fluorophenylacetylene derivatives followed by an intramolecular annulation to afford benzo[b]furan and benzo[b]thiophene derivatives. Moreover, structurally important 2,2'-bisbenzofuran scaffolds are provided in good yields.

APA, Harvard, Vancouver, ISO, and other styles

23

Ramazani, Ali, Morteza Rouhani, and Sang Woo Joo. "Silica Nanoparticles from Rice Husk Ash: A Green Catalyst for the One-Pot Three-Component Synthesis of Benzo[B]Furan Derivatives." Advanced Materials Research 875-877 (February 2014): 202–7. http://dx.doi.org/10.4028/www.scientific.net/amr.875-877.202.

Full text

Abstract:

Reaction of an isocyanide with an iminium ion intermediate, formed by reaction between an electronpoor 2-hydroxybenzaldehyde derivative and a secondary amine in the presence of silica nanoparticles proceeds smoothly at room temperature to afford benzo [b] furan derivatives in high yields.

APA, Harvard, Vancouver, ISO, and other styles

24

Lu, Dan, Ya Zhou, Qin Li, et al. "Synthesis, In Vitro Antitumor Activity and Molecular Mechanism of Novel Furan Derivatives and their Precursors." Anti-Cancer Agents in Medicinal Chemistry 20, no. 12 (2020): 1475–86. http://dx.doi.org/10.2174/1871520620666200424130204.

Full text

Abstract:

Background: Compounds featuring furan nucleus exhibit diverse biological properties. Lots of furan derivatives have been explored as pharmaceutical compounds. Hence it is of great interest to explore furan derivatives and their precursors as antitumor agents. Objective: A series of novel furan derivatives and their precursors (1-36) were synthesized from α-haloketones and β-dicarbonyl compounds. Methods: The reactions between β-dicarbonyl compounds and α-haloketones under basic conditions produced tricarbonyls or dihydrofurans, which were then condensed into their corresponding furan products.

APA, Harvard, Vancouver, ISO, and other styles

25

Tsao, Wen-Xuan, Bing-Huei Chen, Pinpin Lin, Shu-Han You, and Tsai-Hua Kao. "Analysis of Furan and Its Derivatives in Food Matrices Using Solid Phase Extraction Coupled with Gas Chromatography-Tandem Mass Spectrometry." Molecules 28, no. 4 (2023): 1639. http://dx.doi.org/10.3390/molecules28041639.

Full text

Abstract:

The objective of this study was to develop a simultaneous analysis method of furan and its 10 derivatives in different food commodities. The results indicated that furan and its 10 derivatives could be separated within 9.5 min by using a HP-5MS column and gas chromatography–tandem mass spectrometry (GC-MS/MS) with multiple reaction monitoring mode for detection. Furthermore, this method could resolve several furan isomers, such as 2-methyl furan and 3-methyl furan, as well as 2,3-dimethyl furan and 2,5-dimethyl furan. The most optimal extraction conditions were: 5 g of the fruit or juice sampl

APA, Harvard, Vancouver, ISO, and other styles

26

Vessally, Esmail, Ali Ramazani, Hana Shabrendi, Roghaie Ghadimi, and Morteza Rouhani. "A Novel Four-Component Reaction between Secondary Amines and Hydroxybenzaldehydes with Isocyanides in Water: An Efficient One-Pot and Green Synthesis of Benzo[b]furan Derivatives." Journal of Chemistry 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/761982.

Full text

Abstract:

The novel benzo[b]furan derivatives,7a–i, were synthesized and characterized by Ugi four-component reaction between 2-hydroxybenzaldehyde derivative1, a secondary amine2, and an isocyanide3in water. Those reactions were carried out at room temperature with moderate to good yields in one pot.

APA, Harvard, Vancouver, ISO, and other styles

27

Bonilla-Castañeda, Sandra M., Andrés F. Villamizar-Mogotocoro, and Vladimir V. Kouznetsov. "[4-(3,4-Dimethoxyphenyl)-3,6-dimethyl-2-phenyl-3,4-dihydroquinolin-1(2H)-yl)](furan-2-yl)methanone." Molbank 2022, no. 3 (2022): M1413. http://dx.doi.org/10.3390/m1413.

Full text

Abstract:

A N-(2,4-diaryltetrahydroquinolin-1-yl) furan-2-carboxamide derivative, [4-(3,4-dimethoxyphenyl)-3,6-dimethyl-2-phenyl-3,4-dihydroquinolin-1(2H)-yl)](furan-2-yl)methanone, was synthesized in a two-step procedure from p-toluidine, benzaldehyde, and trans-methyl-isoeugenol as commercial starting reagents through a sequence of Povarov cycloaddition reaction/N-furoylation processes. The structure of the compound was fully characterized by IR, 1H, 13C-NMR, and X-ray diffraction data. Such types of derivatives are known as relevant therapeutic agents exhibiting potent anticancer, antibacterial, anti

APA, Harvard, Vancouver, ISO, and other styles

28

Sleziak, Róbert, and Alžbeta Krutošíková. "Cycloaddition Reactions of Furo[2,3-b]pyrroles." Collection of Czechoslovak Chemical Communications 64, no. 2 (1999): 321–28. http://dx.doi.org/10.1135/cccc19990321.

Full text

Abstract:

Reactions of furo[2,3-b]pyrroles with dimethyl butynedioate and ethyl propynoate were investigated. The reaction course is influenced by the substituents on the fused system. Products of [4+2]cycloaddition to the furan ring leading to indole derivatives have been observed. In the case of the reaction of methyl 6H-furo[2,3-b]pyrrole-5-carboxylate (1a) with dimethyl butynedioate, products of [4+2]cycloaddition to the furan ring as well as of Michael addition to the pyrrole ring leading to N-substituted indole derivative 3 have been observed.

APA, Harvard, Vancouver, ISO, and other styles

29

Warthegau, Stefan S., and Sebastian Meier. "Tailoring the Formation of Functionalized Furans from Glucose in Water with Nature-Sourced Catalysts and In Situ NMR." Molecules 29, no. 6 (2024): 1368. http://dx.doi.org/10.3390/molecules29061368.

Full text

Abstract:

Chain elongation of unprotected carbohydrates in water under mild conditions remains a challenge both in chemical and biochemical synthesis. The Knoevenagel addition or condensation enables transformations to bioactive scaffolds for pharmaceutical and agrochemical compounds. Unfortunately, the catalysts in use for these transformations often reduce the green metrics of the transformations. Here, we use in situ NMR visualizations to explore the prospective use of natural catalysts for the synthesis of triple- and quadruple-functionalized furan- or dihydrofuran-derivatives from glucose and malon

APA, Harvard, Vancouver, ISO, and other styles

30

Santiago-Martínez, Leoncio, César Irán González-Falcón, Jaime Reyes-Hernández, Brent E. Handy, and María-Guadalupe Cárdenas-Galindo. "Improved Light Hydrocarbon, Furans, and BTEX Production from the Catalytic Assisted Pyrolysis of Agave salmiana Bagasse over Silica Mesoporous Catalysts." Catalysts 13, no. 3 (2023): 548. http://dx.doi.org/10.3390/catal13030548.

Full text

Abstract:

The pyrolysis of the biomass Agave salmiana bagasse (10 K/min, ambient to 700 °C) was investigated in the absence and presence of Aerosil and MCM-41 catalysts. MCM-41 was synthetized using a typical hydrothermal method and characterized with XRD, SAXS, SEM, TEM, and nitrogen physisorption to confirm the presence of unidimensional 3.4 nm diameter pores. Pyrolysis products were monitored online with mass spectrometry (MS), analyzing the production of 29 different compounds, clustered in several groups, namely, olefins (ethene, 2-butene, 1,3-butadiene), oxygenated compounds (methanol, 2-methylbut

APA, Harvard, Vancouver, ISO, and other styles

31

Dutta, Saikat, Linglin Wu, and Mark Mascal. "Production of 5-(chloromethyl)furan-2-carbonyl chloride and furan-2,5-dicarbonyl chloride from biomass-derived 5-(chloromethyl)furfural (CMF)." Green Chemistry 17, no. 7 (2015): 3737–39. http://dx.doi.org/10.1039/c5gc00936g.

Full text

Abstract:

Biomass-derived CMF is oxidized to the acid chloride CMFCC in a single step using inexpensive t-butyl hypochlorite. Likewise, DFF, also a CMF derivative, is oxidized directly to the diacid chloride FDCC. The products are platforms for a variety of chemical derivatives of carbohydrates.

APA, Harvard, Vancouver, ISO, and other styles

32

Condurso, Concetta, Fabrizio Cincotta, and Antonella Verzera. "Determination of furan and furan derivatives in baby food." Food Chemistry 250 (June 2018): 155–61. http://dx.doi.org/10.1016/j.foodchem.2017.12.091.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Nichols, Nancy N., Tristan A. Lunde, Kevin C. Graden, et al. "Chemotaxis to Furan Compounds by Furan-Degrading Pseudomonas Strains." Applied and Environmental Microbiology 78, no. 17 (2012): 6365–68. http://dx.doi.org/10.1128/aem.01104-12.

Full text

Abstract:

ABSTRACTTwoPseudomonasstrains known to utilize furan derivatives were shown to respond chemotactically to furfural, 5-hydroxymethylfurfural, furfuryl alcohol, and 2-furoic acid. In addition, a LysR-family regulatory protein known to regulate furan metabolic genes was found to be involved in regulating the chemotactic response.

APA, Harvard, Vancouver, ISO, and other styles

34

Dr., K. Chandra Sekhar M. S.* K. Sravana Lakshmi. "A Review Article on Recent Advances in The Pharmacological Diversification of Imidazole Derivatives." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 1581–99. https://doi.org/10.5281/zenodo.15205082.

Full text

Abstract:

Furan a five membered aromatic heterocyclic ring system with O present at 1st position made up of 4C and4 H atoms furan ring is a part of many natural productslikeFurano flavonoid, furanocoumarins, etc... Furan nucleus show several biological applications and also shows strong affinity for a range of receptorsfuran and its derivatives are used in synthesis of many novel drugs. The antibacterial, antifungal, antiviral, anti-inflammatory, analgesic, anti-depressant, anti-anxiolytic, anti-Parkinson, anti-glaucoma, muscle-relaxant, anti-hypertensive, diuretics, anti-ulcer, anti-aging, anti-cancer,

APA, Harvard, Vancouver, ISO, and other styles

35

Baptista, Marlene, Joana T. Cunha, and Lucília Domingues. "Establishment of Kluyveromyces marxianus as a Microbial Cell Factory for Lignocellulosic Processes: Production of High Value Furan Derivatives." Journal of Fungi 7, no. 12 (2021): 1047. http://dx.doi.org/10.3390/jof7121047.

Full text

Abstract:

The establishment of lignocellulosic biorefineries is dependent on microorganisms being able to cope with the stressful conditions resulting from the release of inhibitory compounds during biomass processing. The yeast Kluyveromyces marxianus has been explored as an alternative microbial factory due to its thermotolerance and ability to natively metabolize xylose. The lignocellulose-derived inhibitors furfural and 5-hydroxymethylfurfural (HMF) are considered promising building-block platforms that can be converted into a wide variety of high-value derivatives. Here, several K. marxianus strain

APA, Harvard, Vancouver, ISO, and other styles

36

KASHIHARA, Hiroshi, Hiroshi SUEMUNE, Naomi TSUNEHIRO, and Kiyoshi SAKAI. "Facile synthesis of furan derivatives." CHEMICAL & PHARMACEUTICAL BULLETIN 38, no. 9 (1990): 2581–82. http://dx.doi.org/10.1248/cpb.38.2581.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

H. Kohnke, Franz, Melchiorre F. Parisi, Françisco M. Raymo, Paul A. O'Neil, and David J. Williams. "Acenaphane derivatives from furan macrocycles." Tetrahedron 50, no. 30 (1994): 9113–24. http://dx.doi.org/10.1016/s0040-4020(01)85377-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Tameko, Joseph Eric Mbasso, Jean Rodolphe Chouna, Pépin Nkeng-Efouet-Alango, Leon Azefack Tapondjou, and Norbert Sewald. "Furan derivatives from Lannea kerstingii." Phytochemistry Letters 20 (June 2017): 282–84. http://dx.doi.org/10.1016/j.phytol.2017.04.040.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Vranová, J., and Z. Ciesarová. "Furan in food – a review." Czech Journal of Food Sciences 27, No. 1 (2009): 1–10. http://dx.doi.org/10.17221/2843-cjfs.

Full text

Abstract:

Furan and its derivatives were identified in a small number of heat-treated foods back in the 60’s and 70’s. In May 2004, US Food and Drug Administration published a report on the occurrence of parent furan in a number of thermally treated foods. Since furan has been classified as “possibly carcinogenic to human” by IARC, a great concern has been addressed to the analysis of this substance naturally-occurring in food. This paper gives a short overview on the mechanistic pathways of the parent furan formation in food by degradation of amino acids and/or reducing sugars, and oxidation of ascorbi

APA, Harvard, Vancouver, ISO, and other styles

40

Javed, Muhammad Salman, Muhammad Zubair, Komal Rizwan, and Muhammad Jamil. "In Vitro Anti-Microbial Activity and Anti-Cancer Potential of Novel Synthesized Carbamothioyl-Furan-2-Carboxamide Derivatives." Molecules 28, no. 12 (2023): 4583. http://dx.doi.org/10.3390/molecules28124583.

Full text

Abstract:

A series of carbamothioyl-furan-2-carboxamide derivatives were synthesized using a one-pot strategy. Compounds were obtained in moderate to excellent yields (56–85%). Synthesized derivatives were evaluated for their anti-cancer (HepG2, Huh-7, and MCF-7 human cancer cell lines) and anti-microbial potential. Compound p-tolylcarbamothioyl)furan-2-carboxamide showed the highest anti-cancer activity at a concentration of 20 μg/mL against hepatocellular carcinoma, with a cell viability of 33.29%. All compounds showed significant anti-cancer activity against HepG2, Huh-7, and MCF-7, while indazole an

APA, Harvard, Vancouver, ISO, and other styles

41

Wailzer, Bettina, Johanna Klocker, Peter Wolschann, and Gerhard Buchbauer. "Structural Features for Furan-Derived Fruity and Meaty Aroma Impressions." Natural Product Communications 11, no. 10 (2016): 1934578X1601101. http://dx.doi.org/10.1177/1934578x1601101014.

Full text

Abstract:

Furan derivatives are part of nearly all food aromas. They are mainly formed by thermal degradation of carbohydrates and ascorbic acid and from sugar-amino acid interactions during food processing. Caramel-like, sweet, fruity, nutty, meaty, and burnt odor impressions are associated with this class of compounds. In the presented work, structure-activity relationship (SAR) investigations are performed on a series of furan derivatives in order to find structural subunits, which are responsible for the particular characteristic flavors. Therefore, artificial neural networks are applied on a set of

APA, Harvard, Vancouver, ISO, and other styles

42

Kraľovičová, Eva, Alžbeta Krutošíková, and Jaroslav Kováč. "Preparation and reactions of thieno[3,2-b]furan derivatives." Collection of Czechoslovak Chemical Communications 51, no. 8 (1986): 1685–91. http://dx.doi.org/10.1135/cccc19861685.

Full text

Abstract:

Reactions of 3-(5-aryl-2-furyl)propenoic, 3-(2-benzo[b]furyl)propenoic and 3-(5-ethoxycarbonyl-4H-furo[3,2-b]-2-pyrrolyl)propenoic acids with thionyl chloride in the presence of triethylbenzylammonium chloride were investigated. The obtained 2-arylthieno[3,2-b]-furan-5-carboxylic acid chlorides Ia - Ic and 3-chlorothieno[3,2-b]benzo[b]furan-2-carboxylic acid chloride afforded in substitution nucleophilic reactions the corresponding esters V and carboxylic acids VI which were decarboxylated to VII. 3-Chlorothieno[3,2-b]benzo[b]furan-2-carboxylic acid chloride (Id), 6-ethoxycarbonyl-3-chlorothie

APA, Harvard, Vancouver, ISO, and other styles

43

Nagarsha, K. M., T. M. Sharanakumar, D. Ramesh, et al. "NOVEL SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF N-(5BROMO-2-(5-PHENYL1,3,4-OXADIAZOL-2-YL)NAPHTHA[2,1-B]FURAN-1- YL)ACETAMIDE AND N-(5-NITRO-2-(5-PHENYL-1,3,4- OXADIAZOL-2-YL)NAPHTHA[2,1-BFURAN-1-YL]ACETAMIDE AND THEIR DERIVATIVES." RASAYAN Journal of Chemistry 16, no. 01 (2023): 167–75. http://dx.doi.org/10.31788/rjc.2023.1618088.

Full text

Abstract:

The novel derivatives of naphtho-furan such N-(5bromo-2-(5-phenyl-1,3,4-oxadiazol-2-yl)naphtha[2,1-b]furan-1- yl)acetamide (8), N-(5-bromo-2-(hydrazinecarbonyl)naphtha[2,1-b]furan-1-yl]acetamide (7), ethyl-1-acetamido-5- bromonaphtho[2,1-b]furan-2-carboxylate (6), N-(5-nitro-2-(5-phenyl-1,3,4-oxadiazol-2-yl)naphtha[2,1-bfuran-1- yl]acetamide (5),N-(2-(hydrazinecarbonyl)-5-nitronaphtho[2,1-b]furan-1-yl)acetamide (4), ethyl-1-acetamido-5- nitrpnaphtho[2,1-b]furan-2-carboxylate (3), are prepared by ethyl-1-acetamidonaphtho[2,1-b]furan-2-carboxyate and ethyl 1-aminonaphtho[2,1-b]furan-2-carboxylat

APA, Harvard, Vancouver, ISO, and other styles

44

Hashem, Aya B., Olfat A. Nief, and Abdulkader M. Noori. "Synthesis, Characterization, and Antimicrobial Evaluation of Thiadiazole Derivatives Derived from 2-Amino-5-Thio-1,3,4-Thiadiazole." Iraqi Journal of Industrial Research 11, no. 2 (2024): 87–96. http://dx.doi.org/10.53523/ijoirvol11i2id402.

Full text

Abstract:

This manuscript introduces a series of novel Schiff base and heterocyc-licring compounds, focusing on derivatives of 1,3-oxazepine and thiazo-lidinone.The derivative (2-Hydroxy-N-(5-mercapto-[1,3,4] thiadiazol-2-yl)-2-phenyl-acetamide was created by reacting ethyl mandelate ester[M1] and 2-amino-5-thio-1,3,4-thiadiazole compound to produce new compound [M2] and after that, compound [M2] was reacted with hydrazine hydrate 99% in dry DMF solvent, yielding the compound (N-(5-Hydrazino-[1,3,4]thiadiazol-2-yl)-2-hydroxy-2-phenyl-acetamide [M3]. In contrast , the Schiff base compound [M4] were synth

APA, Harvard, Vancouver, ISO, and other styles

45

Puciová, Monika, Peter Ertl, and Štefan Toma. "Synthesis of Ferrocenyl-Substituted Heterocycles: The Beneficial Effect of the Microwave Irradiation." Collection of Czechoslovak Chemical Communications 59, no. 1 (1994): 175–85. http://dx.doi.org/10.1135/cccc19940175.

Full text

Abstract:

The synthesis of ferrocenyl-substituted thiophenes, furans, pyrroles, pyrimidine and pyrazole has been studied. 2-Ferrocenylpyrroles were prepared from ferrocenyl ketoximes and acetylene in DMSO - KOH mixture whereas 3-chloro-3-ferrocenylacrylaldehydes and thioglycolic or glycolic acids were the starting materials for the synthesis of the thiophene and furan derivatives. The yields were significantly enhanced when the reactions were carried out in a microwave oven. The lower stability of 2-ferrocenylfuran in comparison with 2-ferrocenylthiophene is discussed on the basis of semiempirical quant

APA, Harvard, Vancouver, ISO, and other styles

46

Shoji, Taku, Shunji Ito, and Masafumi Yasunami. "Synthesis of Azulene Derivatives from 2H-Cyclohepta[b]furan-2-ones as Starting Materials: Their Reactivity and Properties." International Journal of Molecular Sciences 22, no. 19 (2021): 10686. http://dx.doi.org/10.3390/ijms221910686.

Full text

Abstract:

A variety of synthetic methods have been developed for azulene derivatives due to their potential applications in pharmaceuticals and organic materials. Particularly, 2H-cyclohepta[b]furan-2-one and its derivatives have been frequently used as promising precursors for the synthesis of azulenes. In this review, we describe the development of the synthesis of azulenes by the reaction of 2H-cyclohepta[b]furan-2-ones with olefins, active methylenes, enamines, and silyl enol ethers as well as their reactivity and properties.

APA, Harvard, Vancouver, ISO, and other styles

47

Matiichuk, Yulia, Yuriy Horak, Taras Chaban, Ihor Chaban, and Vasyl Matiychuk. "Synthesis and anticancer properties of 3-furan-2-yl-2-(4-furan/thiophen-2-ylthiazol-2-yl)acrylonitrile derivatives." Current Chemistry Letters 11, no. 3 (2022): 269–74. http://dx.doi.org/10.5267/j.ccl.2022.4.002.

Full text

Abstract:

By the reaction of (4-furan-2-yl-thiazol-2-yl)- 3a and (4-thiophen-2-yl-thiazol-2-yl)- 3b acetonitriles with furfural 4 and 5-arylfurfyrals 5a-g 3-furan-2-yl-2-(4-furan/thiophen-2-ylthiazol-2-yl)acrylonitrile derivatives 6a-i were obtained. Anticancer activity screening was carried out within the framework of Developmental Therapeutic Program of the National Cancer Institute's (DTP, NCI, Bethesda, Maryland, USA). It was found out that (2E)-3-(2-furyl)-2-[4-(2-furyl)-1,3-thiazol-2-yl]acrylonitrile (6a) and 2-(4-thiophen-2-yl-thiazol-2-yl)-acrylonitriles 6h,i possessed low activity and 2-(4-fura

APA, Harvard, Vancouver, ISO, and other styles

48

Puckowska, Anna, Magdalena Gawel, Marlena Komorowska, et al. "Synthesis and Structural Characterization of Pyridine-2,6-dicarboxamide and Furan-2,5-dicarboxamide Derivatives." Molecules 27, no. 6 (2022): 1819. http://dx.doi.org/10.3390/molecules27061819.

Full text

Abstract:

Derivatives based on pyridine-2-6- and furan-2,5-dicarboxamide scaffolds reveal numerous chemical properties and biological activities. This fact makes them an exciting research topic in supramolecular and coordination chemistry and in discovering new pharmacologically-active compounds. This work aimed to obtain a series of symmetrical pyridine-2-6- and furan-2,5-dicarboxamides through a condensation reaction of the appropriate acyl chlorides and aromatic amides. Successful syntheses were confirmed with NMR spectroscopy. We solved their crystal structures for seven compounds; two pyridine and

APA, Harvard, Vancouver, ISO, and other styles

49

Jiang, Yongjun, Zhen Lei, Jiebin Fang, Yanping Wu, and Chengpeng Sun. "Non-Steroidal FXR Agonistic Dimeric 2-Methyl-4-(1-glycerol)furan with Lipid-Lowering Activities from Marine-Derived Nocardiopsis sp. ZSN1." Marine Drugs 23, no. 3 (2025): 92. https://doi.org/10.3390/md23030092.

Full text

Abstract:

Five novel 2-methyl-4-(1-glycerol)furan (MGF) dimers, namely nocardifuran A (1), 13-acetyl-nocardifuran A (2), 15-epi-nocardifuran A (3), nocardifuran B (4), and nocardifuran C (5), were isolated from the Gause liquid fermentation of the marine-derived Nocardiopsis sp. ZSN1. Their structures were elucidated through HRESIMS, 1D and 2D NMR spectroscopic data analysis, and ECD calculations. Compounds 1–4 were identified as derivatives of MGF with its rearrangement of furan or pyran derivatives, while compound 5 was identified as the derivative of MGF with an indole derivative. These MGF dimers, r

APA, Harvard, Vancouver, ISO, and other styles

50

Beiko, Alona V., Oleksandr L. Kobzar, Maryna V. Kachaeva, Stepan G. Pilyo, Olexandr P. Kozachenko, and Andriy I. Vovk. "Rhodanine-based 4-(furan-2-yl)benzoic acids as inhibitors of xanthine oxidase." Ukr. Bioorg. Acta 2023, Vol. 18, N2 18, no. 2 (2023): 31–40. http://dx.doi.org/10.15407/bioorganica2023.02.031.

Full text

Abstract:

A series of rhodanine derivatives bearing 4-(furan-2-yl)benzoic acid moiety were synthesized and studied as inhibitors of xanthine oxidase. This enzyme is a known target for allopurinol and febuxostat used in the treatment of hyperuricemia, gout, and other diseases. The synthesized compounds with different substituents in position 3 of the rhodanine ring showed in vitro inhibitory activities towards xanthine oxidase in a low micromolar concentration range. The 4-(furan-2-yl)benzoic acid derivative with a fragment of N-unsubstituted rhodanine was found to have the lowest IC50 value which does n

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!