Academic literature on the topic 'Furin site'

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Journal articles on the topic "Furin site"

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Tian, Sun. "A 20 Residues Motif Delineates the Furin Cleavage Site and its Physical Properties May Influence Viral Fusion." Biochemistry Insights 2 (January 2009): BCI.S2049. http://dx.doi.org/10.4137/bci.s2049.

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Furin is a proprotein convertase that proteolytically cleaves protein precursors to yield functional proteins. Efficient cleavage depends on the presence of a specific sequence motif on the substrate. Currently, the cleavage site motif is described as a four amino acid pattern: R-X-[K/R]-R⇓. However, not all furin cleavage recognition sites can be described by this pattern and not all R-X-[K/R]-R⇓ sites are cleaved by furin. Since many furin substrates are involved in the pathogenesis of viral infection and human diseases, it is important to accurately characterize the furin cleavage site moti
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Yamada, Yoshiyuki, and Ding Xiang Liu. "Proteolytic Activation of the Spike Protein at a Novel RRRR/S Motif Is Implicated in Furin-Dependent Entry, Syncytium Formation, and Infectivity of Coronavirus Infectious Bronchitis Virus in Cultured Cells." Journal of Virology 83, no. 17 (2009): 8744–58. http://dx.doi.org/10.1128/jvi.00613-09.

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ABSTRACT The spike (S) protein of the coronavirus (CoV) infectious bronchitis virus (IBV) is cleaved into S1 and S2 subunits at the furin consensus motif RRFRR537/S in virus-infected cells. In this study, we observe that the S2 subunit of the IBV Beaudette strain is additionally cleaved at the second furin site (RRRR690/S) in cells expressing S constructs and in virus-infected cells. Detailed time course experiments showed that a peptide furin inhibitor, decanoyl-Arg-Val-Lys-Arg-chloromethylketone, blocked both viral entry and syncytium formation. Site-directed mutagenesis studies revealed tha
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Cheng, Jinlong, Ye Zhao, Gang Xu, et al. "The S2 Subunit of QX-type Infectious Bronchitis Coronavirus Spike Protein Is an Essential Determinant of Neurotropism." Viruses 11, no. 10 (2019): 972. http://dx.doi.org/10.3390/v11100972.

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Some coronaviruses (CoVs) have an extra furin cleavage site (RRKR/S, furin-S2′ site) upstream of the fusion peptide in the spike protein, which plays roles in virion adsorption and fusion. Mutation of the S2′ site of QX genotype (QX-type) infectious bronchitis virus (IBV) spike protein (S) in a recombinant virus background results in higher pathogenicity, pronounced neural symptoms and neurotropism when compared with conditions in wild-type IBV (WT-IBV) infected chickens. In this study, we present evidence suggesting that recombinant IBV with a mutant S2′ site (furin-S2′ site) leads to higher
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Papa, Guido, Donna L. Mallery, Anna Albecka, et al. "Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion." PLOS Pathogens 17, no. 1 (2021): e1009246. http://dx.doi.org/10.1371/journal.ppat.1009246.

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Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infects cells by binding to the host cell receptor ACE2 and undergoing virus-host membrane fusion. Fusion is triggered by the protease TMPRSS2, which processes the viral Spike (S) protein to reveal the fusion peptide. SARS-CoV-2 has evolved a multibasic site at the S1-S2 boundary, which is thought to be cleaved by furin in order to prime S protein for TMPRSS2 processing. Here we show that CRISPR-Cas9 knockout of furin reduces, but does not prevent, the production of infectious SARS-CoV-2 virus. Comparing S processing in furin knockou
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Wanyiri, Jane W., Roberta O'Connor, Geneve Allison, et al. "Proteolytic Processing of the Cryptosporidium Glycoprotein gp40/15 by Human Furin and by a Parasite-Derived Furin-Like Protease Activity." Infection and Immunity 75, no. 1 (2006): 184–92. http://dx.doi.org/10.1128/iai.00944-06.

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ABSTRACT The apicomplexan parasite Cryptosporidium causes diarrheal disease worldwide. Proteolytic processing of proteins plays a significant role in host cell invasion by apicomplexan parasites. In previous studies, we described gp40/15, a Cryptosporidium sp. glycoprotein that is proteolytically cleaved to yield two surface glycopeptides (gp40 and gp15), which are implicated in mediating infection of host cells. In the present study, we showed that biosynthetically labeled gp40/15 is processed in Cryptosporidium parvum-infected HCT-8 cells. We identified a putative furin cleavage site RSRR↓ i
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Siner, Joshua I., Julie M. Crudele, Courtney T. Connolly, et al. "Unexpected Role of PACE/Furin Cleavage Site in FVIII Biology: Implications for Hemophilia a Therapy." Blood 124, no. 21 (2014): 105. http://dx.doi.org/10.1182/blood.v124.21.105.105.

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Abstract The paired basic amino acid cleaving enzyme (PACE)/Furin is a protein convertase system that plays a vital role in several biological processes, including coagulation. The propeptide processing of human FIX by PACE/Furin is a critical posttranslational modification, so cells co-expressing PACE/Furin and FIX are used for production of clinical recombinant protein. In the development of recombinant B-domain deleted (BDD) FVIII for hemophilia A (HA), a 14 amino acid B-domain sequence containing a putative cleavage site for PACE/Furin was retained because it was believed to be critical fo
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Geiselhart, Verena, Patrizia Bastone, Tore Kempf, Martina Schnölzer, and Martin Löchelt. "Furin-Mediated Cleavage of the Feline Foamy Virus Env Leader Protein." Journal of Virology 78, no. 24 (2004): 13573–81. http://dx.doi.org/10.1128/jvi.78.24.13573-13581.2004.

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ABSTRACT The molecular biology of spuma or foamy retroviruses is different from that of the other members of the Retroviridae. Among the distinguishing features, the N-terminal domain of the foamy virus Env glycoprotein, the 16-kDa Env leader protein Elp, is a component of released, infectious virions and is required for particle budding. The transmembrane protein Elp specifically interacts with N-terminal Gag sequences during morphogenesis. In this study, we investigate the mechanism of Elp release from the Env precursor protein. By a combination of genetic, biochemical, and biophysical metho
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Cui, Yanzhen, Renee Hackenmiller, Linnea Berg, et al. "The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor." Genes & Development 15, no. 21 (2001): 2797–802. http://dx.doi.org/10.1101/gad.940001.

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Proteolytic maturation of proBMP-4 is required to generate an active signaling molecule. We show that proBMP-4 is cleaved by furin in a sequential manner. Cleavage at a consensus furin site adjacent to the mature ligand domain allows for subsequent cleavage at an upstream nonconsensus furin site within the prodomain. BMP-4 synthesized from precursor in which the upstream site is noncleavable is less active, signals at a shorter range, and accumulates at lower levels than does BMP-4 cleaved from native precursor. Conversely, BMP-4 cleaved from precursor in which both sites are rapidly cleaved i
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Kubo, Yoshinao, Manya Bakatumana Hans, Taisuke Nakamura, and Hideki Hayashi. "The Furin Protease Dependence and Antiviral GBP2 Sensitivity of Murine Leukemia Virus Infection Are Determined by the Amino Acid Sequence at the Envelope Glycoprotein Cleavage Site." International Journal of Molecular Sciences 25, no. 18 (2024): 9987. http://dx.doi.org/10.3390/ijms25189987.

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Host restriction factor GBP2 suppresses the replication of the ecotropic Moloney murine leukemia virus (E-MLV) by inhibiting furin protease, which cleaves the viral envelope glycoprotein (Env) into surface (SU) and transmembrane (TM) subunits. We analyzed the impacts of GBP2 on the infection efficiency mediated by MLV Envs of different strains of ecotropic Moloney, polytropic Friend, amphotropic, and xenotropic MLV-related (XMRV) viruses. Interestingly, the Envs of ecotropic Moloney and polytropic Friend MLV were sensitive to the antiviral activity of GBP2, while XMRV and amphotropic Envs show
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Gendron, Fernand-Pierre, Sébastien Mongrain, Patrick Laprise, et al. "The CDX2 transcription factor regulates furin expression during intestinal epithelial cell differentiation." American Journal of Physiology-Gastrointestinal and Liver Physiology 290, no. 2 (2006): G310—G318. http://dx.doi.org/10.1152/ajpgi.00217.2005.

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CDX2, a member of the caudal family of transcription factors, is involved in enterocyte lineage specification. CDX2 activates many intestine-specific genes, such as sucrase-isomaltase and lactase-phlorizin hydrolase (LPH), and adhesion proteins, namely, LI-cadherin and claudin-2. In this study, we show that the proprotein convertase furin, involved in proteolytic maturation of proprotein substrates including LPH and cell surface proteins, is a CDX2 target. Indeed, expression of the rat furin homolog was induced 1.5-fold, as determined by microarray experiments that compared control with CDX2-e
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Dissertations / Theses on the topic "Furin site"

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Gross, Andrew Jacob. "Discovery of an Allosteric Site on Furin, contributing to Potent Inhibition: A Promising Therapeutic for the Anemia of Chronic Inflammation." BYU ScholarsArchive, 2014. https://scholarsarchive.byu.edu/etd/6537.

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Anemia of chronic inflammation (ACI) is a condition that develops in a setting of chronic immune activation. ACI is characterized and triggered by inflammatory cytokines and the disruption of iron homeostasis. Hepcidin, a small peptide hormone, is the master regulator of iron homeostasis, and rapidly responds to iron supply and demand. Under conditions of chronic inflammation, hepcidin is elevated, and alters the way that iron is absorbed and disrupted throughout the body, resulting in disrupted iron homeostasis through inhibition of the iron exporter protein ferroportin. Anemia arises whe
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Oltmann, Meredith Leigh. "Disruption of the furin cleavage site in mouse Notch 1 results in cardiovascular malformations due to hypomorphic Notch 1 signaling." Diss., Restricted to subscribing institutions, 2009. http://proquest.umi.com/pqdweb?did=1872078271&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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Kobertz, William Rudolf 1968. "Total synthesis of a Furan-side psoralen-thymidine monoadduct and its biochemical applications." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/50343.

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Hickey, Ashley N. "Expression of CTB-proinsulin in transgenic chloroplasts." Honors in the Major Thesis, University of Central Florida, 2008. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/1088.

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This item is only available in print in the UCF Libraries. If this is your Honors Thesis, you can help us make it available online for use by researchers around the world by following the instructions on the distribution consent form at http://library.ucf.edu/Systems/DigitalInitiatives/DigitalCollections/InternetDistributionConsentAgreementForm.pdf You may also contact the project coordinator, Kerri Bottorff, at kerri.bottorff@ucf.edu for more information.<br>Bachelors<br>Burnett College of Biomedical Sciences<br>Molecular and Microbiology
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Nelson, Steevenson. "Characterization of furin protease sensitive site processing and it's effects on sindbis virus assembly and buddingcharacterization of furin protease sensitive site processing and it's effects on sindbis virus assembly and budding." 2005. http://www.lib.ncsu.edu/theses/available/etd-11172005-133503/unrestricted/etd.pdf.

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Chen, Yu-Jou, and 陳語柔. "Recombinant Zika virus-like particles containing a multiple furin cleavage site for vaccine design." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/r8d3x3.

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Jheng, Jyun-Fong, and 鄭竣丰. "Synthesis and Characterization of Copolymers Based on 5,6-difluoro-benzo-2,1,3-thiadiazole Acceptor and Thiophene, Furan and Selenophene Donor Units and Their Copolymers Containing Porphyrin Side Chain Units for Photovoltaics Applications." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/aqcw28.

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碩士<br>國立交通大學<br>應用化學系碩博士班<br>101<br>This research is aimed to enhance the performances of low band gap (LBG) polymer in the optoelectronic applications, such as organic field-effect transistors (OFETs) and organic polymer photovoltaics (OPVs). Two strategies were used to design high performance LBG polymers, including promoting of the intermolecular non-covalent interaction strength and effect of congeners of the state-of-art LBG polymers. In the first part of this study, 5,6-difluoro-benzo-2,1,3-thiadiazole acceptor unit was copolymerized with quaterthiophene donor unit (PTh4FBT). This fluori
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Books on the topic "Furin site"

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Dalmau, Antoni. Siete días de furia: Barcelona y la Semana Trágica (julio de 1909). Ediciones Destino, 2009.

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Siete días de furia: Barcelona y la Semana Trágica (julio de 1909). Ediciones Destino, 2009.

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Siete días de furia y puñales: De la conjura contra Casado a la última esperanza azul. La Esfera de los Libros, 2022.

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RUNCAN, PATRICIA. Consiliere și mentorare cu impact. Seria AUTENTIC. Vol. 2. EDITURA DE VEST, 2021. http://dx.doi.org/10.51820/autentic.2021.vol.2.

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"Prefață: Consiliere și mentorare cu impact Călăuzirea spirituală: de la „avva” Antichității la mentorul de azi Sfântul apostol Pavel le scria romanilor: „Dar cum vor chema pe Acela în care n-au crezut? Și cum vor crede în Acela despre care n-au auzit? Și cum vor auzi despre El, fără ca cineva să predice? Și cum vor predica, dacă n-au fost trimiși? Astfel, credința vine din cele auzite, iar cele auzite, prin Cuvântul Lui Dumnezeu.” (Romani 10: 14-15). Nimeni n-a plecat la propovăduire de capul lui. 1. Inițial, Isus „a chemat pe cine a vrut” (chemarea; vocația divină: gr. kaleo; lat. voco/are =
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Book chapters on the topic "Furin site"

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Sriram, Anitha, Yojana Bhor, Srushti Mahajan, et al. "SARS-COV-2 Ingress - Triggering COVID-19 Infection." In An Update on SARS-CoV-2: Damage-response Framework, Potential Therapeutic Avenues and the Impact of Nanotechnology on COVID-19 Therapy Volume 1. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815039863122010006.

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An important keynote that should be kept in mind is that to curb the spreading of the SARS-CoV-2 virus, one should understand how it enters host cells. This review provides deep insights into mechanistic intervention approaches of 2019- nCoV that target its host cell entry mechanisms. Majorly, there are three entryways for 2019-nCoV to target and infect the host cell, which is highly expressed with ACE2. The ‘S’- priming of TMPRSS2 associated cleavage is the primary entryway for a virus to access the targeted host cell via mediating the fusion process. The second way for virus entry is through
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Olsnes, S. "Pseudomonas aeruginosa exotoxin A." In Guidebook to Protein Toxins and Their Use in Cell Biology. Oxford University PressOxford, 1997. http://dx.doi.org/10.1093/oso/9780198599555.003.0017.

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Abstract Pseudomonas aeruginosa exotoxin A (PEA, MW 66 kDa, 613 amino acids, sequence accession number: PSEETA K01397) consists of three major domains (Allured et al. 1986), as indicated in Fig. 1. The N-terminal domain la (amino acids 1-252) binds to the ai-macroglobulin receptor at the cell surface (Kounnas et al. 1992), domain II (amino acids 253-364) mediates translocation of itself and domain Ill to the cytosol, and the (-terminal domain Ill (amino acids 405-613) catalyses the transfer of ADP-ribose from NAD to the diphthamide residue of elongation factor 2, which is thereby inactivated (
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Kumar, Vijay. "Learning from Bats to Escape from Potent or Severe Viral Infections." In Origin and Impact of COVID-19 Pandemic Originating From SARS-CoV-2 Infection Across the Globe [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.98916.

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The COVID-19 pandemic that started in December 2019 in Wuhan city, China has created chaos all over the world with over 185 million infection cases and 4 million deaths world-wide. The pathogen behind COVID-19 has been identified as severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) that is more close to the previous SARS-CoV responsible for SARS epidemic 2002–2003. Although, SARS-CoV-2 also differs from SARS-CoV in many aspects as indicated by genetic studies. For example, SARS-CoV does not have a furin binding domain or site, whereas its presence in SARS-CoV-2 spike (S) protein inc
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Jenkins, Paul R. "Metallated heterocyclic compounds." In Organometallic Reagents in Synthesis. Oxford University Press, 1992. http://dx.doi.org/10.1093/hesc/9780198556664.003.0006.

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This chapter focuses on a small selection of heterocyclic compounds providing an estimate of how any heterocyclic ring can be metalated. It considers the metallation of the heterocycles furan, thiophen, and N-methylindole, which are deprotonated by butyllithium on a carbon α to the heteroatom. It also explains the inductive effect of the heteroatom as it stabilizes the carbanion by withdrawing electron density from it, noting that this heteroatom effect is one of the main ideas in explaining aromatic lithiation. The chapter discusses 2-lithiothiophen and 2-lithiofuran, which are considered the
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Bourbigot, Serge, Jinhan Lu, Tao Zhang, et al. "Plant-derived Fire Retardants." In Green Fire Retardants for Polymeric Materials. Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/bk9781839169793-00004.

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Bio-based fire retardants represent one of the most promising directions of next-generation fire retardants due to their sustainability, environmental benefits and comparable efficiency to current non-based counterparts. Many plant-derived feedstocks, such as lignin, phytic acid (PA), polysaccharides (e.g., alginates) and furan as well as their derivatives, have shown promising applications in creating fire-retardant polymeric materials. This chapter focuses on their use as fire retardants, alone or in combination with other fire retardants, or as starting materials for synthesizing bio-based
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Hussain, Athar, Ayushman Bhattacharya, and Arfat Ahmed. "Plastic Waste Pollution and Its Management in India." In Advanced Treatment Techniques for Industrial Wastewater. IGI Global, 2019. http://dx.doi.org/10.4018/978-1-5225-5754-8.ch005.

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Plastic, one of the most preferred materials in today's industrial world, is posing a serious threat to the environment and consumer health in many direct and indirect ways. The global plastic production increased over years due to the vast applications of plastics in many sectors. More than 50% of the plastic waste generated in the country is recycled and used in the manufacture of various plastic products. The remaining half is disposed of at landfill sites or simply burned in incinerators. The burning of plastics, especially PVC, releases this dioxin and also furan into the atmosphere. In t
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Taber, Douglass. "Protection of Organic Functional Groups." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0011.

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Several noteworthy new developments in the protection and deprotection of alcohols have been reported. Andrea Biffis of the Università di Padova has developed (Adv. Synth. Catal. 2007, 349, 2485) a Rh catalyst that effected silylation of alcohols such as 1 to the TES ether 2 at just 0.01% loading. Joshua Rokach of the Florida Institute of Technology has observed (Tetrahedron Lett. 2007, 48, 5289) that the reverse reaction, Rh-catalyzed desilylation of 3, was highly selective for the less congested site, even removing the usually less reactive TBS ether of 3 and leaving the more hindered TES eth
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Taber, Douglass F. "Development of Flow Reactions." In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0015.

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For a review of a monograph by C. Wiles and P. Watts on applications of flow reactors in organic synthesis, see Org. Process. Res. Dev. 2011, 15, 947. For a review by Klavs S. Jensen of MIT of flow approaches, see Angew. Chem. Int. Ed. 2011, 50, 7502. Hans-René Bjørsvik of the University of Bergen described (Org. Process. Res. Dev. 2011, 15, 997) a multijet oscillating disc microreactor, and Andreas Schmid of the Technische Universität Dortmund (Adv. Synth. Catal. 2011, 353, 2511) and László Poppe of the Budapest University of Technology and Economics discussed (Adv. Synth. Catal. 2011, 353, 2
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Taber, Douglass. "Stereocontrolled Alkaloid Construction: Rhazinicine (Gaunt), 9-epi-Pentazocine (Zhai and Li), Fawcettidine (Dake), Strychnine (Padwa), and Yohimbine (Jacobsen)." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0059.

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The power of catalytic C-H functionalization is illustrated by the elegant synthesis of rhazinicine 3 devised (Angew. Chem. Int. Ed. 2008, 47, 3004) by Matthew J. Gaunt of the University of Cambridge. The key step in the synthesis was the oxidative cyclization of 1 to 2. Although 1 has many C-H sites, the Pd catalyst selected for the α position of the pyrrole, leading, after intramolecular Heck addition and β-hydride elimination, to the alkene 2. Reduction and macrolactamization completed the synthesis of 3. Hongbin Zhai of the Shanghai Institute of Organic Chemistry and Zhong Li of East China
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Conference papers on the topic "Furin site"

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Pribulova, Alena, Peter Futas, Patrik Fedorko, Maria Mihalikova, and Maria Mihalikova. "THE EFFECT OF THE AMOUNT OF BINDER ON THE PROPERTIES OF BRIQUETTES PREPARED FROM FOUNDRY DUST." In 24th SGEM International Multidisciplinary Scientific GeoConference 24. STEF92 Technology, 2024. https://doi.org/10.5593/sgem2024/4.1/s18.41.

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Briquetting is the pressing of dusty materials into pieces of the same shape and size. Briquetting can be done without a binder or with the addition of a binder to the briquetting mixture. Briquettes can have any shape, but the most common is the shape of a cylinder. The briquettes must be strong enough to eliminate the possibility of damage during transport and must be strong enough even at high temperatures. The briquettes have a regular shape, have the same weight, are more durable and easier to transport. They are ecologically safe and it is possible to use carbon filling in briquettes to
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Padish, Randy, and Donald Blair. "A Case Study for a FRP Chlorinated Solvent Fume Transport System." In CORROSION 2000. NACE International, 2000. https://doi.org/10.5006/c2000-00552.

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Abstract Fumes from a pharmaceutical production plant and its support facilities are drawn into one of two regenerative thermal oxidizers (RTOs) where they are destroyed to acceptable regulatory standards. Furan and vinyl ester fiberglass reinforced plastic (FRP) ducts are successfully being used to transport the fumes from their origin to the RTOs. The fumes range from concentrated (above upper explosive limit) to dilute (&amp;lt;15% lower explosive limit) mixtures of various chlorinated and non-chlorinated solvents. Each section of the fume transport system (FTS) is specifically designed bas
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Akhmetov, V. V. "Some Features of Bohai Funeral Rite (Based on Materials of Sites of the Hailan River Valley, PRC)." In IV Международный научный форум "Наследие". SB RAS, 2023. http://dx.doi.org/10.25205/978-5-6049863-1-8-16-20.

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There are several places of concentration of Bohai sites in the Northeast China. One of these places is the valley of the Hailan River. Bone remains were found only at several burial grounds (Yingcheng, Fumin, Beida, Zhongping, Longtoushan). A relatively large number of bone remains have been found at the Beida burial ground. The most common funeral rite was primary and primary in combination with secondary. Cremation is recorded at the Zhongping burial ground. Primary burials in combination with secondary ones prevailed at the Longtoushan burial ground (Longhai site). In the valley of the Hai
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Klonos, Panagiotis, Lazaros Papadopoulos, Zoi Terzopoulou, Apostolos Kyritsis, George Papageorgiou, and Dimitris Bikiaris. "Tuning the Crystallizability of Renewable Poly(alkylene 2,5-furan-dicarboxylate)s by In-Situ Adding Various Nanosized Nucleation Agents." In The First International Conference on “Green” Polymer Materials 2020. MDPI, 2020. http://dx.doi.org/10.3390/cgpm2020-07224.

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Warrener, Ronald, Douglas Butler, Shudong Wang, and Edward Tiekink. "Site and Stereoselectivities in the High Pressure Reactionof Furan with Dimethyl 7-isopropylidenebicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate and Tetramethyl7-isopropylidenebicyclo[2.2.1]hepta-2,5-diene-2,3,5,6-tetracarboxylate." In The 3rd International Electronic Conference on Synthetic Organic Chemistry. MDPI, 1999. http://dx.doi.org/10.3390/ecsoc-3-01728.

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Maslakci, Neslihan Nohut, and Aysegul Uygun Oksuz. "RF rotating plasma modified of chitosan with 3,4-ethylenedioxythiophene, thiophene and furan: Investigation of nanofibers in-situ with quartz crystal microbalance (QCM) and electrospinning system." In 2015 IEEE International Conference on Plasma Sciences (ICOPS). IEEE, 2015. http://dx.doi.org/10.1109/plasma.2015.7179748.

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Balakrishnan, Anandh, and Mrinal C. Saha. "Effect of Ultrasound and Strain Rate on Tensile Behavior of Neat Thermoplastic Polyurethane Thin Films." In ASME 2010 International Mechanical Engineering Congress and Exposition. ASMEDC, 2010. http://dx.doi.org/10.1115/imece2010-39197.

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Thermoplastic Polyurethane (TPU) thin films have many applications in engineering and biomedical fields. Examples include moisture sensors, load cells, optical element and biocompatible stens. The TPU is a block copolymer naturally phase segregates into thermodynamically incompatible hard- and soft-segments. The size of the segments and their spatial distribution can significantly affect the microstructure and mechanical properties of the TPU. In this paper, we propose to investigate the effect of ultrasound energy on mechanical properties of TPU thin films fabricated via a solution route util
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Iino, Kenji, and Masayuki Nakao. "A Fatal Accident Case and Lessons for Entertainment Engineering." In ASME 2013 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/detc2013-12133.

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On May 5th, 2007, a six-car stand-up roller coaster Fujin-Raijin II, during a ride, dropped one of its two wheel assemblies from the second car. Losing its balance, the second car tilted to the left by about 45 degrees. The rider in the left side of the front row jammed her head between the passenger support structure and the handrail of the maintenance walkway and was killed instantly. The next day, the Ministry of Land, Infrastructure, Transport and Tourism (MLIT) instructed a nationwide inspection of similar attractions. Investigations revealed that the main axle had a crack caused by metal
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Lei, Hanwu, Shoujie Ren, James Julson, Lu Wang, Quan Bu, and Roger Ruan. "Microwave Torrefaction of Corn Stover and Tech-Economic Analysis." In ASME 2011 International Manufacturing Science and Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/msec2011-50230.

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Microwave torrefaction of corn stover with particle size of 4 mm was investigated and the effects of reaction temperature and time on the yields of volatile, bio-oil and torrefied biomass were determined. The response surface analysis of the central composite design (CCD) showed that the yields of volatile, bio-oil and torrefied biomass were significantly affected by the reaction temperature and time. Three linear models were developed to predict the yields of conversion products as a function of temperature and time. A first order reaction kinetics was also developed to model the corn stover
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Reports on the topic "Furin site"

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Allcock, Harry R., Jeffrey A. Dodge, Leon S. Van Dyke, and Charles R. Martin. Polyphosphazenes Bearing Polymerizable Pyrrole, Thiophene and Furan Side Groups: Synthesis and Chemical Oxidation. Defense Technical Information Center, 1992. http://dx.doi.org/10.21236/ada249747.

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