Academic literature on the topic 'Furocoumarins'

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Journal articles on the topic "Furocoumarins"

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Sun, Weiyi, Megan S. Rice, Min K. Park, et al. "Intake of Furocoumarins and Risk of Skin Cancer in 2 Prospective US Cohort Studies." Journal of Nutrition 150, no. 6 (2020): 1535–44. http://dx.doi.org/10.1093/jn/nxaa062.

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ABSTRACT Background In prior studies, higher citrus consumption was associated with higher risk of cutaneous malignant melanoma, squamous cell carcinoma (SCC), and basal cell carcinoma (BCC). Furocoumarins, compounds with phototoxicity and photocarcinogenicity in citrus, may be responsible for the association. Objectives The objective of the study was to investigate the association between furocoumarin intake and skin cancer risk. Methods A total of 47,453 men from the Health Professionals Follow-Up Study (HPFS) and 75,291 women from the Nurses’ Health Study (NHS) with diet data collected ever
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MANDERFELD, MICHELLE M., H. WILLIAM SCHAFER, P. MICHAEL DAVIDSON, and EDMUND A. ZOTTOLA. "Isolation and Identification of Antimicrobial Furocoumarins from Parsley." Journal of Food Protection 60, no. 1 (1997): 72–77. http://dx.doi.org/10.4315/0362-028x-60.1.72.

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Photoactive furocoumarins extracted from four varieties of fresh and freeze-dried parsley leaves inhibited a DNA repair-deficient Escherichia coli in a photobiological assay. Using media-modified assays, the human pathogens E. coli O157:H7 and Listeria monocytogenes, the spoilage microorganism Erwinia carotovora, and Listeria innocua were also inhibited. Pseudomonas fragi was not inhibited. Minimum concentrations of Forest Green parsley powder in agar which showed inhibition ranged from 0.12% to 8.0% depending on the microorganism. Ultraviolet light (UV) at 365 nm for 60 min used to photoactiv
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Vedaldi, Daniela, Sergio Caffieri, Giorgia Miolo, Francesco Dall'Acqua, and Paola Arslan. "Dark and Photohemolysis of Erythrocytes by Furocoumarins." Zeitschrift für Naturforschung C 43, no. 11-12 (1988): 888–92. http://dx.doi.org/10.1515/znc-1988-11-1215.

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Abstract It has been shown that various furocoumarins are able to cause dark hemolysis in red blood cells (RBC). However, this effect is evident only at relatively high furocoumarin concentrations (4.6 x 10-4 M) - much higher than those used in photosensitization experiments or photochemotherapeutic treatments. Among the various furocoumarins examined in this study, only psoralen (Ps) and 3-carbethoxypsoralen (3-CPs) showed strong photohemolytic effects, while the other compounds revealed little or no activity. This fact indicates that Ps and 3-CPs are able to induce selective damage to the ce
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Scordino, Monica, Leonardo Sabatino, Adalgisa Belligno, and Giacomo Gagliano. "Characterization of Polyphenolic Compounds in Unripe Chinotto (Citrus myrtifolia) Fruit by HPLC/PDA/ESI/MS-MS." Natural Product Communications 6, no. 12 (2011): 1934578X1100601. http://dx.doi.org/10.1177/1934578x1100601218.

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The flavonoid and furocoumarin composition was investigated of peel and pulp tissues of unripe fruits of Citrus myrtifolia Rafinesque, an ingredient of the popular soft drink “chinotto”. Compound separation and identification was made using an HPLC-PDA detector coupled to ESI/MS/MS in positive and negative mode. Eighteen compounds (3-hydroxy-3-methylglutaryl-, C- and O-glycosyl flavonoids, furocoumarins and polymethoxylated flavones) were identified and quantified. Data indicated that the overall amount of flavonoids and furocoumarins in peel was higher than in the pulp, even though their rela
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Kaiser, Isabelle, Anja Rappl, Lena S. Bolay, Annette B. Pfahlberg, Markus V. Heppt, and Olaf Gefeller. "The Impact of Dietary Intake of Furocoumarins and Furocoumarin-Rich Foods on the Risk of Cutaneous Melanoma: A Systematic Review." Nutrients 17, no. 8 (2025): 1296. https://doi.org/10.3390/nu17081296.

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Background/Objectives: Furocoumarins, chemical compounds found in many plant species, have a photosensitizing effect on the skin when applied topically and, by interacting with ultraviolet radiation (UVR), stimulate melanoma cells to proliferate. Whether dietary intake of furocoumarins acts as a melanoma risk factor has been investigated in several epidemiological studies, which are synthesized in our systematic review. Methods: The study protocol was registered with PROSPERO (registration number: CRD42023428596). We conducted an in-depth literature search in three databases coupled with forwa
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Girennavar*, Basavaraj, Narayan Bhat, Jennifer Brodbelt, Michael Pikulski, G. K. Jayaprakasha, and Bhimanagouda S. Patil. "Grapefruit-Drug Interaction: Levels of Furocoumarin in Different Varieties." HortScience 39, no. 4 (2004): 863E—864. http://dx.doi.org/10.21273/hortsci.39.4.863e.

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Grapefruit juice contain furanocoumarin derivatives which are known to interact with various drugs such as felodipine, leading to the increased bioavailability. Due to very low concentrations of furocoumarin in grapefruit juice, isolation of these compounds has been a challenge to researchers. Five grapefruit (Citrus paradisi Macf.) varieties such as `Marsh White', `Duncan', `Rio Red', `Orange Flesh', and `Mexican Red' were harvested and analyzed. Samples were extracted successively three times with ethyl acetate until all furocoumarins were extracted. The dried extract was reconstituted in me
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Laczkó Zöld, Eszter, Csenge Kis, Erzsébet Nagy-György, Erzsébet Domokos, Elek Ferencz, and Zoltán-István Szabó. "Fast Determination of Furocoumarins in Food Supplements Containing Heracleum sphondylium L. Using Capillary Electrophoresis." Foods 14, no. 13 (2025): 2348. https://doi.org/10.3390/foods14132348.

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Hercaleum sphondylium L., commonly known as hogweed, is a plant species that has been employed as an ingredient in food supplements aimed at enhancing reproductive organ functionality, restoring hormonal equilibrium, and producing an aphrodisiac effect. Importantly, the European Food Safety Authority (EFSA) has designated it as a “substance of possible concern for human health” when found in food and food supplements, as detailed in the EFSA compendium of botanicals. Given the potential health consequences associated with the ingestion of furocoumarin-containing plants, the primary objective o
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Kerekes, Diána, Attila Csorba, Beáta Gosztola, Éva Németh-Zámbori, Tivadar Kiss, and Dezső Csupor. "Furocoumarin Content of Fennel—Below the Safety Threshold." Molecules 24, no. 15 (2019): 2844. http://dx.doi.org/10.3390/molecules24152844.

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Furocoumarins are known for their phototoxic and potential carcinogenic effects. These types of compounds have previously been reported from fennel (Foeniculum vulgare Mill.), a widely used medicinal plant and spice; however, no reliable quantitative data are available on the occurrence of these compounds in fennel fruits. For the first time, we report a comprehensive analysis of fennel fruit samples of different origins, representing a wide range of accessions for their furocoumarin content. Psoralene, 5-methoxypsoralene (bergapten), and imperatorin contents of 33 fennel samples were analyzed
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Woźniak, Łukasz, Marzena Połaska, Krystian Marszałek, and Sylwia Skąpska. "Photosensitizing Furocoumarins: Content in Plant Matrices and Kinetics of Supercritical Carbon Dioxide Extraction." Molecules 25, no. 17 (2020): 3805. http://dx.doi.org/10.3390/molecules25173805.

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Furocoumarins are a group of plant phytoalexins exhibiting various bioactive properties; the most important of which are photosensitization and alteration of P450 cytochrome activity. Supercritical fluid extraction with carbon dioxide has been proposed as a green alternative for an organic solvent extraction of the furocoumarins. Four plant matrices rich in furocoumarins were extracted with CO2 at a temperature of 80 °C and pressure of 40 MPa, as these conditions were characterized by the highest solubility of furocoumarins. The extracts collected were analyzed using the HPLC method and the re
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Niu, Chao, Deng Zang, and Haji Akber Aisa. "Study of Novel Furocoumarin Derivatives on Anti-Vitiligo Activity, Molecular Docking and Mechanism of Action." International Journal of Molecular Sciences 23, no. 14 (2022): 7959. http://dx.doi.org/10.3390/ijms23147959.

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Vitiligo is a common chronic dermatological abnormality that afflicts tens of millions of people. Furocoumarins isolated from Uygur traditional medicinal material Psoralen corylifolia L. have been proven to be highly effective for the treatment of vitiligo. Although many furocoumarin derivatives with anti-vitiligo activity have been synthesized, their targets with respect to the disease are still ambiguous. Fortunately, the JAKs were identified as potential targets for the disease and its inhibitors have been proved to be effective in the treatment of vitiligo in many clinical trials. Thus, si
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Dissertations / Theses on the topic "Furocoumarins"

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Jones, Stuart George. "Photophysical and photobiological properties of furocoumarins." Thesis, Keele University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259468.

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Holland, Julie. "Studies on the genetic and biochemical properties of a PUVA hyper-resistant mutant of Escherichia coli." Thesis, Nottingham Trent University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259195.

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Rocha, Thaíza Carvalho da. "Estudo termoanalítico de furanocumarinas de Brosimum gaudichaudii Trécul." Universidade Federal de Goiás, 2012. http://repositorio.bc.ufg.br/tede/handle/tede/3296.

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Submitted by Jaqueline Silva (jtas29@gmail.com) on 2014-10-06T18:08:43Z No. of bitstreams: 2 Dissertação - Thaíza Carvalho da Rocha - 2012.pdf: 1513291 bytes, checksum: 5cdef676b716525fc5590bddb862c72f (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Approved for entry into archive by Jaqueline Silva (jtas29@gmail.com) on 2014-10-06T19:16:52Z (GMT) No. of bitstreams: 2 Dissertação - Thaíza Carvalho da Rocha - 2012.pdf: 1513291 bytes, checksum: 5cdef676b716525fc5590bddb862c72f (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>
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Knox, C. N. "On pulsed irradiation studies of furocoumarins and related compounds used in the photochemotherapy of hyperproliferative skin diseases." Thesis, University of the West of Scotland, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.373415.

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Cicchetti, Esméralda. "Développement de méthodes d’analyse pour l’étude de la qualité des matières premières de parfumerie et d’arômes." Thesis, Montpellier, Ecole nationale supérieure de chimie, 2017. http://www.theses.fr/2017ENCM0008.

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Le contrôle qualité (CQ) des matières premières (MP) de parfumerie et d’arômes fait appel à un grand nombre de techniques analytiques pour déterminer la composition qualitative (caractérisation) et quantitative d’un ingrédient.La caractérisation fait appel à des méthodes spectroscopiques. Lorsque les MP sont complexes, un couplage avec des techniques séparatives est nécessaire comme avec la chromatographie en phase gazeuse (CPG) ou liquide (CL), parfois précédées d’une étape de purification. L’identification formelle des analytes pourra ensuite se faire par exemple par spectrométrie de masse o
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Doerper, Sébastien. "Modification de la synthèse des furocoumarines chez Ruta graveolens L. par une approche de génie métabolique." Thesis, Vandoeuvre-les-Nancy, INPL, 2008. http://www.theses.fr/2008INPL070N/document.

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La rue officinale (Ruta graveolens L) est une plante connue comme étant particulièrement riche en métabolites secondaires et produisant notamment des molécules d’intérêt pharmaceutique comme les furocoumarines. Nous avons tenté par une approche de génie métabolique d’augmenter la teneur en furocoumarines produites dans les plantes. La mise en place de telles approches nous a également permis de mieux comprendre les mécanismes de régulation de la voie de biosynthèse des phénylpropanoïdes. Pour atteindre ces objectifs nous avons transformé la rue avec différents gènes placés sous le contrôle d’u
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Bouque, Virginie. "Étude de la production de métabolites secondaires par des cultures in vitro de Psoralées (leguminosae)." Vandoeuvre-les-Nancy, INPL, 1997. http://docnum.univ-lorraine.fr/public/INPL_T_1997_BOUQUE_V.pdf.

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Les furocoumarines linéaires sont des molécules photosensibilisantes qui présentent une réelle importance économique de par leurs propriétés pharmacologiques. Nous avons envisagé leur production par des cultures in vitro de plantes du genre Psoralea. Des cals et des racines transformées ont été initiées et analysées par CLHP. Aucune trace de furocoumarine n'a pu être détectée. En revanche, nous détectons la présence de daidzéine et de coumestrol. Une analyse de la plante entière de Psoralea cinerea révèle un profil métabolique très différent de celui des cultures in vitro: les teneurs en furoc
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Fracarolli, Letícia. "Isolamento, caracterização e avaliação da atividade fotossensibilizadora de cumarinas e furanocumarinas extraídas de espécies de Citrus." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/60/60135/tde-28102015-154212/.

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O crescente aumento da tolerância aos fungicidas atualmente utilizados é um dos principais problemas tanto na área clínica quanto na agrícola e tem estimulado o desenvolvimento de estratégias alternativas para o controle de fungos patogênicos, tais como o tratamento fotodinâmico antimicrobiano (TFA), que pode utilizar fotossensibilizadores (FS) de origem natural ou sintética. Alguns FS, como as cumarinas e furanocumarinas, são produzidos por espécies de Citrus como limão Tahiti (Citrus latifolia) e toranjas (Citrus paradisi). O presente estudo investigou o TFA in vitro de conídios do fungo fit
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Larbat, Romain Bourgaud Frédéric. "Contribution à l'étude des P450 impliqués dans la biosynthèse des furocoumarines." S. l. : S. n, 2006. http://www.scd.inpl-nancy.fr/theses/2006_LARBAT_R.pdf.

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Gravot, Antoine. "Étude de P450s impliqués dans la biosynthèse des furocoumarines chez Ruta graveolens." Vandoeuvre-les-Nancy, INPL, 2002. http://www.theses.fr/2002INPLA63N.

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Ruta graveolens est une plante présentant des fortes teneurs en 5-méthoxypsoralène (5-MOP), une furocoumarine particulièrement intéressante d'un point de vue médical. Nous avons choisi d'étudier les étapes enzymatiques clés de la biosynthèse de cette molécule. Ces étapes sont catalysées par des cytochromes P450. Les travaux effectués au cours de cette thèse ont porté sur le clonage et la caractérisation de plusieurs de ces P450s (la Cinnamate 4-hydroxylase (C4H) et deux psoralène monooxygénases). Un ADNc complet codant pour la C4H a été isolé, et exprimé dans la levure. Après avoir caractérisé
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Books on the topic "Furocoumarins"

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IARC Working Group on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Some naturally occurring and synthetic food components, furocoumarins, and ultraviolet radiation. World Health Organization, International Agency for Research on Cancer, 1986.

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Per, Svendsen, and Hau Jann, eds. Handbook of laboratory animal science. CRC Press, 1994.

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P, Gasparro Francis, ed. Psoralen DNA photobiology. CRC Press, 1988.

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Marko, Jean. Etude par Polarisation Nucléaire Induite photochimiquement (photo-CIDNP) de composés photosensibilisants à activité thérapeutique: Phénothiazines et furocoumarines. A.N.R.T. Université Pierre Mendès France Grenoble 2, 1986.

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Handbook of Laboratory Animal Science, Volume II. CRC-Press, 1994.

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Handbook of Laboratory Animal Science: Selection and Handling of Animals in Biomedical Research. CRC-Press, 1994.

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(Producer), WHO, ed. Vol 40 IARC Monographs: Some Naturally Occurring and Synthetic food components, Furocoumarins and Ultraviolet Radiation (IARC Monographs on the Evaluation of the Carcinogenic Risk o). World Health Organisation, 1986.

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Hau, Jann, and Steven J. Schapiro. Handbook of Laboratory Animal Science: Essential Principles and Practices. Taylor & Francis Group, 2021.

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Hau, Jann, Steven J. Schapiro, and Van Hoosier, Gerald L., Jr. Handbook of Laboratory Animal Science. Taylor & Francis Group, 2004.

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Hau, Jann, and Steven J. Schapiro. Handbook of Laboratory Animal Science: Essential Principles and Practices. Taylor & Francis Group, 2021.

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Book chapters on the topic "Furocoumarins"

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Averbeck, Dietrich. "Photoaddition by Furocoumarins." In Photobiology in Medicine. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4899-1313-5_5.

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Dall’Acqua, Francesco, Sergio Caffieri, Giovanni Rodighiero, et al. "Photoreactions of Furocoumarins (Psoralens and Angelicins)." In Primary Photo-Processes in Biology and Medicine. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-1224-6_15.

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Dall’Acqua, Francesco, Giovanni Rodighiero, Dietrich Averbeck, et al. "Biological and Medicinal Aspects of Furocoumarins." In Primary Photo-Processes in Biology and Medicine. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-1224-6_16.

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Benkiki, N., M. Benkhaled, Zahia Kabouche, and C. Bruneau. "Heraclenol and Isopimpinellin: Two Rare Furocoumarins from Ruta montana." In Biodiversity. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4419-9242-0_36.

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Pathak, Madhu A., and M. Dalle Carbonare. "Melanogenic Potential of Various Furocoumarins in Normal and Vitiliginous Skin." In Light in Biology and Medicine. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-0709-9_47.

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Uesugi, Y., and H. Takahashi. "Photochemical Reaction of Furocoumarins: Time-Resolved Absorption and Resonance-Raman Studies." In Springer Proceedings in Physics. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-85060-8_31.

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Tanew, A., B. Ortel, and H. Hönigsmann. "5-Methoxypsoralen and Other New Furocoumarins in the Treatment of Psoriasis." In Light in Biology and Medicine. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-0709-9_24.

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Dall’Acqua, Francesco, and Daniela Vedaldi. "Photosensitized Action on the Cell Membrane and Its Constituents by Furocoumarins." In Light in Biology and Medicine. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-5991-3_16.

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Rodighiero, Giovanni. "New Aspects of the Mechanism of Action of Furocoumarins (Psoralens and Angelicins)." In Photobiology. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3732-8_105.

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Hiserodt, Richard, and Li Chen. "An LC/MS/MS Method for the Analysis of Furocoumarins in Citrus Oil." In ACS Symposium Series. American Chemical Society, 2012. http://dx.doi.org/10.1021/bk-2012-1098.ch006.

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Conference papers on the topic "Furocoumarins"

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Utz, Sergei R., Yurii P. Sinichkin, Valery V. Tuchin, and Alexander B. Pravdin. "Laser fluorescence spectroscopy of furocoumarins in human epidermis." In OE/LASE'93: Optics, Electro-Optics, & Laser Applications in Science& Engineering, edited by R. Rox Anderson, Lawrence S. Bass, Stanley M. Shapshay, John V. White, and Rodney A. White. SPIE, 1993. http://dx.doi.org/10.1117/12.147021.

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Mottaghipisheh, Javad, Márta Nové, Gabriella Spengler, Norbert Kúsz, Judit Hohmann, and Dezső Csupor. "Antiproliferative and cytotoxic activities of furocoumarins of Ducrosia anethifolia." In Fiatal Gyógynövénykutatók Fóruma. Magyar Gyógyszerésztudományi Társaság Gyógynövény Szakosztálya, 2018. http://dx.doi.org/10.14232/fgykf.2018.b1.

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Pravdin, Alexander B., Yurii P. Sinichkin, Valery V. Tuchin, and Sergei R. Utz. "Laser fluorescence spectroscopy of some linear furocoumarins in human epidermis." In Laser Spectroscopy of Biomolecules: 4th International Conference on Laser Applications in Life Sciences, edited by Jouko E. Korppi-Tommola. SPIE, 1993. http://dx.doi.org/10.1117/12.146205.

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Kerekes, Diána. "Phytochemical and pharmacological study of furocoumarins in Citrus trifoliata L." In 2nd Symposium of Young Researchers on Pharmacognosy. Department of Pharmacognosy, University of Szeged, Faculty of Pharmacy, 2021. http://dx.doi.org/10.14232/syrpharmacognosy.2021.a11.

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Bryantseva, N. G. "Influence of substitution on the T-T absorption spectra in furocoumarins." In SPIE Proceedings, edited by Gennadii G. Matvienko and Victor A. Banakh. SPIE, 2006. http://dx.doi.org/10.1117/12.722440.

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Baskakov, Pavel V., and Mikhail M. Stolnitz. "Mathematical modeling of cell proliferation dynamics in psoriatic epidermis sensitized by the furocoumarins under UVA radiation." In International Workshop on Nonlinear Dynamics and Structures in Biology and Medicine: Optical and Laser Technologies, edited by Valery V. Tuchin. SPIE, 1997. http://dx.doi.org/10.1117/12.266242.

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Csupor, D., D. Kerekes, B. Gosztola, and É. Zámbori-Németh. "The furocoumarin content of Foeniculum vulgare The furocoumarin content of Foeniculum vulgare." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608431.

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Reports on the topic "Furocoumarins"

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Patil, Bhimanagouda S., Ron Porat, G. K. Jayaprakasha, and K. N. C. Murthy. Optimization of Postharvest Storage Conditions to Maintain Fruit Quality and Health Maintaining Properties of Grapefruit. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7613879.bard.

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Antioxidant activity of fruits is gaining wide interest among consumers due to its importance in counteracting oxidative stress, free radicals and preventing DNA damage. Oxygen radical absorbance capacity (ORAC) assay is one of the commonly used assays to measure the antioxidant activity, which is based on hydrogen atom transfer mechanism. Furocoumarins present in grapefruit are reported to have antiproliferative activity, induce GST activity, inhibit biofilm formation and increase bioavailability of drugs. In the present project ORAC values were measured of Star Ruby grapefruit undergone ethy
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