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Dissertations / Theses on the topic 'G-4'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Monroy, Carlos Aaron. "Endogenous and exogenous modulation of regulator of G-protein signaling 4." Diss., University of Iowa, 2013. https://ir.uiowa.edu/etd/1366.

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Regulators of G-protein signaling (RGS) proteins are a family of proteins that act as GTPase accelerating proteins (GAPs) through their interaction with GΑ subunits, including GΑo, GΑi, and GΑq but not GΑs. This increased rate of hydrolysis of GTP to GDP temporally regulates G-protein coupled receptor (GPCR) signaling. A member of this family, RGS4, has been implicated in several neurological disorders including Parkinson's Disease (PD). A hallmark of PD is the induction of oxidative stress within dopaminergic neurons. In this thesis, we evaluate the role of oxidative stress, including lipid p

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2

Johnson, Laura Ruth. "Nuclear localisation and function of the g protein-coupled receptor kinase 4 subfamily." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1444448/.

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G protein-coupled receptor kinases (GRKs) are a family of serine/threonine kinases that phosphorylate and mediate densensitisation of agonist-occupied G protein-coupled receptors (GPCRs). Recent evidence suggests, however, additional cellular functions for these enzymes. The seven mammalian GRKs are divided into the GRK1-, GRK2- and GRK4-like subfamilies. I have discovered that GRK4 subfamily members contain functional nuclear localisation sequences (NLSs). The location of the NLSs of GRK5 and 6 is similar whereas the NLS of GRK4 is more N-terminal. Although all members of the GRK4 subfamily c

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3

Bombardieri, Cíntia Raquel. "O circuito p38MAPK/MSK1 influencia o período inicial de diferenciação Th1/2." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-30012008-145520/.

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O sistema imune dos mamíferos forma uma complexa rede de populações celulares especializadas e vias de sinalização extremamente reguladas. Linfócitos T naïve podem diferenciar-se após encontro com o antígeno em pelo menos duas sub-populações distintas, Th1 ou Th2, sendo que o papel do circuito p38MAPK/MSK1 durante este período inicial de ativação não é completamente entendido. Linfócitos T CD4+ naïve humanos foram estimulados in vitro em condições não-polarizantes (Tnp), Th1 ou Th2, na presença de inibidor específico da p38MAPK. As células ativadas e mantidas em condições diferenciadoras Th1 o

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4

Lehmann, Anne [Verfasser], C. [Akademischer Betreuer] Tschierske, and G. [Akademischer Betreuer] Mehl. "Strukturvariationen an bent-core Mesogenen auf 4-Cyanresorcinolbasis / Anne Lehmann. Betreuer: C. Tschierske ; G. Mehl." Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2014. http://d-nb.info/1065670133/34.

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5

Schwarz, Michael [Verfasser], and G. [Akademischer Betreuer] Weiß. "Wärmeleitfähigkeit supraleitender Kompositleiter im Temperaturbereich von 4 K bis 300 K / Michael Schwarz. Betreuer: G. Weiß." Karlsruhe : KIT-Bibliothek, 2009. http://d-nb.info/1013805569/34.

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6

Pang, Paul Daniel. "Role of the Regulator of G protein Signaling 4 in renal ischemic reperfusion injury and repair." Thesis, Boston University, 2013. https://hdl.handle.net/2144/12179.

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Thesis (M.A.)--Boston University<br>Regulator of G protein Signaling 4 (RGS4) has previously been shown to prevent prolonged vasoconstriction by binding to the Gq heterodimer. However, the known anti-inflammatory role of RGS4 has not been applied to reperfusion injury in the context of G protein signaling. The aims of this study is to elucidate the expression pattern of RGS4 in renal reperfusion injury to determine if cell signaling initiated by Angiotensin II, a known ligand of Gαq coupled-receptors, is modulated by RGS4. LacZ reporter animals were used to characterize RGS4 expression during

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7

Ferguson, Colleen Renee. "Charles Villiers Stanford String Quartet No. 4 in G Minor, Op. 99 a critical performance edition." Diss., University of Iowa, 2015. https://ir.uiowa.edu/etd/3082.

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Irish born British composer, teacher, conductor, and organist Sir Charles Villiers Stanford (1852-1924), is today best known for his choral works and as teacher to some of Britain's most successful composers of the twentieth century. Stanford was a prolific composer of numerous genres of music, and his chamber works for strings comprise a significant portion of his total compositional output. A great many of Stanford's chamber compositions were never published and are absent among today's standard chamber music repertoire. Until now, Stanford's String Quartet No. 4 in G minor, Op. 99 has never

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8

Contreras, Saavedra Alexander Matías. "Deteccción de las mutaciones g.7143G>A y g.6930delG del gen calicreína-4 (KLK4) en probandos de familias chilenas afectadas con Amelogénesis Imperfecta hipomadura." Tesis, Universidad de Chile, 2016. http://repositorio.uchile.cl/handle/2250/143033.

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Trabajo de Investigación Requisito para optar al Título de Cirujano Dentista<br>Introducción: Las Amelogénesis Imperfectas (AI) son un grupo heterogéneo de defectos hereditarios que afectan la formación del esmalte dental en calidad y cantidad, pudiendo presentarse en dentición primaria como permanente. Es una condición de baja prevalencia (1 en 700 a 1 en 14000), pero con grandes complicaciones para quienes la padecen en sus formas más severas. Clínicamente se pueden distinguir tres tipos principales: AI hipoplásica, hipocalcificada e hipomadura, cada una relacionadas con una etapa del

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9

Gallo, Sandrine. "Synthèse de nouveaux dérivés 4-O-, 4-S-, 4-NH-alkylés de la pyrido[3,2-g]quinoline : Etude de l'activité de réversion de la chloroquino-résistance chez Plasmodium falciparum et de la MDR en cancérologie." Aix-Marseille 2, 2004. http://www.theses.fr/2004AIX22951.

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10

Sipple, Ernst-Michael. "Réarrangements structuraux et modifications microstructurales associés aux transformations de phases dans le système CaSO 4(s) - H 2O (g)." Dijon, 1999. http://www.theses.fr/1999DIJOS039.

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Les décompositions endothermiques du type solide1solide2+gaz laissent généralement inchangée une fraction importante des liaisons atomiques constitutives de la structure du solide1. Par conséquence la morphologie et les dimensions externes de chaque particule sont préservées (la particule de solide2 est dite pseudomorphe de celle de solide1). Cependant le départ de gaz entraine, en général, une contraction du volume molaire du solide précurseur, il en résulte une fissuration de celui-ci et l'apparition d'une porosité intra-particulaire. Ce travail est consacré à l'étude d'une réaction de ce ty

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11

Ait, Amrane Samir. "Sur le schéma de Hilbert des courbes gauches de degré d et genre g = (d-3)(d-4)/2." Paris 11, 1998. http://www.theses.fr/1998PA112375.

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Pour classifier les courbes gauches (localement de Cohen Macaulay mais pas nécessairement lisses) en géometrie algébrique, on étudie le schéma de Hilbert H_d,g qui paramètre les familles de courbes de degré d et genre g. Dans cette thèse, nous étudions ce schéma, que l'on note alors X_d, dans le cas g = (d-3)(d-4)/2, qui est le premier cas intéressant en genre grand. Pour étudier le schéma de Hilbert H_d,g, M. Martin-Deschamps et D. Perrin ont proposé dans plusieurs articles une philosophie qui repose sur un invariant algébrique des courbes qu'on appelle le module de Rao. Leur philosophie cons

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12

Stambouli, Moncef. "Les clathrates des gaz rares : modelisation et validation experimentale des mecanismes de relachement des gaz rares (g = ar, kr, xe) des clathrates de l'hydroquinone: 3c#6h#4(oh)#2.g." Paris 6, 1995. http://www.theses.fr/1995PA066472.

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La synthese des clathrates est obtenue par une recristallisation indirecte de l'hydroquinone en presence du gaz rare sous pression. La mise au point d'un appareillage experimental a permis l'etude et la comprehension de l'influence des parametres physico-chimiques sur le remplissage de ces composes cristallins non stoechiometriques. Les conditions operatoires ont ete optimisees pour l'obtention de clathrates fortement remplis. La decomposition du clathrate par voie mecanique est un processus controle par une reaction surfacique. Toutefois, la fraction de gaz relachee est beaucoup plus elevee q

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13

Emilsson, Lina. "Detection of Differentially Expressed Genes in Alzheimer's Disease : Regulator of G-protein Signalling 4: A Novel Mediator of APP Processing." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5910.

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14

SANTOS, Manuella Maria Silva. "Avaliação do papel dos polimorfismos nos genes HLA-G e IL4R na susceptibilidade ao Diabetes mellitus tipo 1." Universidade Federal de Pernambuco, 2014. https://repositorio.ufpe.br/handle/123456789/12493.

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Submitted by Amanda Silva (amanda.osilva2@ufpe.br) on 2015-03-13T14:59:49Z No. of bitstreams: 2 DISSERTAÇÃO Manuella Maria Santos.pdf: 1230878 bytes, checksum: 21854ded68897cc54173c33b85cc9f42 (MD5) license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5)<br>Made available in DSpace on 2015-03-13T14:59:49Z (GMT). No. of bitstreams: 2 DISSERTAÇÃO Manuella Maria Santos.pdf: 1230878 bytes, checksum: 21854ded68897cc54173c33b85cc9f42 (MD5) license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Previous issue date: 2014<br>Aproximadamente 40% do risco gené

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15

Moffit, Bryan James. "Elastic scattering of longitudinally polarized electrons from helium-4: A measurement of G(E)(S) at Q2 = 0.1 (GeV/c)2." W&M ScholarWorks, 2007. https://scholarworks.wm.edu/etd/1539623515.

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We have performed the first measurement of the parity-violating asymmetry in the elastic scattering of longitudinally polarized electrons from 4He. The kinematics chosen (Q 2 = 0.1 (GeV/c)2) provide a direct sensitivity to the strange electric form factor GsE with negligible contributions from competing effects. This experiment was performed in June 2004 and July-September 2005 in Hall A at Jefferson Lab. This work represents the experimental setup and analysis of the 2004 dataset.;The final statistical precision, from the combined datasets, put stringent requirements on the systematic err

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16

Hirano, Ayumi. "T dependent B cell help in cattle : immunoregulatory function of interleukin-4 and CD40-CD40L interactions /." free to MU campus, to others for purchase, 1997. http://wwwlib.umi.com/cr/mo/fullcit?p9841150.

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17

Castillo, Miguel Angel Zuñiga. "Expressão do antígeno leucocitário humano G, interleucina 10 e macrófagos M2 no melanoma lentiginoso acral." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5133/tde-31072017-125708/.

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INTRODUÇÃO: O melanoma lentiginoso acral (MLA) é um subtipo pouco frequente do melanoma cutâneo que geralmente apresenta evolução desfavorável e agressiva. Os mecanismos patogenéticos relacionados a essa evolução clínica não são totalmente conhecidos. Atualmente, estudos da literatura enfocam os mecanismos de evasão imunológica relacionados ao microambiente do melanoma, uma vez que os mesmos podem inibir a resposta imune antitumoral permitindo a progressão da doença. A expressão do Antígeno Leucocitário Humano G (HLA-G) e da Interleucina 10 (IL-10) e os macrófagos M2 (MM2) do microambiente tum

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18

Lowak, Jan Holger [Verfasser]. "Isolierung und Charakterisierung von Kinasen G-Protein-gekoppelter Rezeptoren Typ 4, 5 und 6 des südafrikanischen Krallenfroschs Xenopus laevis / Jan Holger Lowak." Ulm : Universität Ulm. Medizinische Fakultät, 2011. http://d-nb.info/101711711X/34.

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19

Meyer, Anne [Verfasser]. "Chromen-4-ones as novel potent and selective ligands for purinoceptor-related class A delta-branch orphan G protein-coupled receptors / Anne Meyer." Bonn : Universitäts- und Landesbibliothek Bonn, 2017. http://d-nb.info/1159955190/34.

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20

MELEDDU, RITA. "Synthesis of different series of small molecules targeting HIV-1 RT, Candida albicans, MAO and G-Quadruplex." Doctoral thesis, Università degli Studi di Cagliari, 2013. http://hdl.handle.net/11584/266235.

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My PhD work has been focused towards four different targets: HIV-1 RT, Candida albicans, Monoamine oxidase, and G-Quadruplex. Thus in order to give the reader a clearer exposition this report has been divided in four different chapters. Each of the chapters has his own figures, schemes, tables and references. The main part of my work has been dedicated to HIV-1 RT, thus this chapter is the major and first one.

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21

PEREIRA, Esdras Edgar Batista. "Associação de polimorfismos de biomarcadores do envelhecimento (TP53, MDM2, UCP2, HLA-G, IL-1a, IL-4 e NFkB1) com a capacidade funcional de idosos." Universidade Federal do Pará, 2016. http://repositorio.ufpa.br/jspui/handle/2011/7258.

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Submitted by Cássio da Cruz Nogueira (cassionogueirakk@gmail.com) on 2017-01-06T14:06:04Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_AssociacaoPolimorfismosBiomarcadores.pdf: 3667708 bytes, checksum: c6fe384e221c6f462e0411cf749bb9ce (MD5)<br>Approved for entry into archive by Edisangela Bastos (edisangela@ufpa.br) on 2017-01-10T13:05:11Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_AssociacaoPolimorfismosBiomarcadores.pdf: 3667708 bytes, checksum: c6fe384e221c6f462

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22

Chaker, Leila. "Réactivité du 4-N,N,-diméthylhydrazonobut-2-enoate de méthyle vis-à-vis des bromonaphtoquinones : synthèses régiospécifiques de dérivés de la benzo(g)quinoléinequinone." Lyon 1, 1995. http://www.theses.fr/1995LYO1T176.

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23

Lilley, Jo-ann Frances. "'n Transkripsie van die manuskrip van De Reis van Jan van Mandeville (Suid-Afrikaanse biblioteek: G 4 B 17) : met 'n uitvoerige algemene inleiding." Thesis, University of Cape Town, 1992. http://hdl.handle.net/11427/23560.

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24

Landelle, Henriette. "Synthèse et étude physicochimique des pyridazino [4,5-b] carbazoles, benzofuro [3,2-f] phtalazines, pyrido [3', 4' : 4,5] furo [3,2-b] indoles, benzothiéno [2,3-g] cinnolines." Caen, 1988. http://www.theses.fr/1988CAEN4072.

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25

Іващук, С. І., та Л. П. Сидорчук. "Поліморфізм генів IL-4 (C-590T), TNF-a (G-308A), PRSS1 (R122H), SPINK1 (N34S) і CFTR (delF508C) у хворих на гострий та загострення хронічного панкреатиту". Thesis, Сумський державний університет, 2016. http://essuir.sumdu.edu.ua/handle/123456789/45039.

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26

Ippolito, Danielle Lorraine. "Regulation of G-protein gated inwardly rectifying potassium channels by tyrosine phosphorylation /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/6295.

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27

Lifson, Farrel. "Specification and Verification of Systems Using Model Checking and Markov Reward Models." Thesis, University of Cape Town, 2004. http://pubs.cs.uct.ac.za/archive/00000134/.

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The importance of service level management has come to the fore in recent years as computing power becomes more and more of a commodity. In order to present a consistently high quality of service systems must be rigorously analysed, even before implementation, and monitored to ensure these goals can be achieved. The tools and algorithms found in performability analysis offer a potentially ideal method to formally specify and analyse performance and reliability models. This thesis examines Markov reward models, a formalism based on continuous time Markov chains, and it's usage in the generati

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28

Peter, Jonathan G. "Delirium in general medical in-patients in South Africa: development of the 4-question "RACY" tool for simple and effective delirium screening by Jonathan G. Peter." Master's thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/3452.

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29

Sudau, Daniela [Verfasser]. "Charakterisierung des Protease-aktivierten Rezeptors Typ 4 (PAR4) und Cathepsins G in der Ösophagusmukosa von Patienten mit gastroösophagealer Refluxerkrankung (GERD) und funktionellem Sodbrennen (FH) / Daniela Sudau." Magdeburg : Universitätsbibliothek, 2017. http://d-nb.info/1151571547/34.

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30

Nirenstein, Shaun. "Fast and Accurate Visibility Preprocessing." Thesis, University of Cape Town, 2003. http://pubs.cs.uct.ac.za/archive/00000101/.

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Visibility culling is a means of accelerating the graphical rendering of geometric models. Invisible objects are efficiently culled to prevent their submission to the standard graphics pipeline. It is advantageous to preprocess scenes in order to determine invisible objects from all possible camera views. This information is typically saved to disk and may then be reused until the model geometry changes. Such preprocessing algorithms are therefore used for scenes that are primarily static. Currently, the standard approach to visibility preprocessing algorithms is to use a form of approximate

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31

Kouzoukas, Dimitrios Elias. "The nitric oxide signaling pathway inhibits intracellular calcium release to prevent neurodevelopmental alcohol toxicity." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/838.

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In the context of fetal alcohol spectrum disorders, we investigated how the nitric oxide (NO) signaling pathway influences intracellular calcium (Ca2+) to mediate alcohol resistance, using a primary cell culture model of cerebellar granule neurons (CGN). Alcohol during fetal brain development triggers abnormally high apoptotic cell death in vulnerable neuronal populations, culminating in serious behavioral and cognitive deficits that persist into adulthood. Prior studies demonstrated that the NO signaling pathway [neuronal nitric oxide synthase → NO → soluble guanylyl cyclase → cyclic guanosin

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32

Libert, Frédérick. "Etude de deux autoantigènes thyroïdiens: la thyroperoxydase et le récepteur de la thyrotropine. Isolement de 4 nouveaux récepteurs membres de la famille des récepteurs couplés aux protéines G." Doctoral thesis, Universite Libre de Bruxelles, 1991. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/213047.

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33

Ivashchuk, S. I. "Influence of genes IL-4 (C-590T), TNF-α (G-308A), PRSS1 (R122H), SPINK1 (N34S) AND CFTR (delF508C) polymorphism on systemic inflammatory response indicators in patients with edematous pancreatitis". Thesis, БДМУ, 2017. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/16903.

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34

Defay, Pierre-Olivier. "Prospectives de recherche du quark de quatri��me g��n��ration u4 avec le d��tecteur ATLAS aupr��s du LHC." Phd thesis, Universit�� Blaise Pascal - Clermont-Ferrand II, 2008. http://tel.archives-ouvertes.fr/tel-00730181.

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Le Mod��le Standard, qui r��git la physique des particules, a ��t�� jusqu'�� pr��sent confirm�� par l'exp��rience. Cependant, les questions qu'il laisse en suspens ont conduit �� proposer plusieurs mod��les permettant son extension. L'un de ces mod��les postulant l'existence d'une quatri��me famille de fermions permet de r��soudre certaines des lacunes du Mod��le Standard. Ce travail, effectu�� dans le cadre de l'exp��rience ATLAS au LHC, pr��sente des m��thodes permetttant de d��couvrir le quark up de quatri��me g��n��ratition u4 produit par paire qui se d��sint��gre de mani��re semileptoniqu

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Möricke, Anja [Verfasser], Chr [Gutachter] Schmidt, G. [Gutachter] Henze, and K. [Gutachter] Welte. "Identifizierung und Charakterisierung einer alternativ gespleißten mRNA der Interleukin-4 Rezeptor alpha-Kette und Untersuchung der biologischen Funktion der verkürzten Rezeptorvariante / Anja Möricke ; Gutachter: Chr. Schmidt, G. Henze, K. Welte." Berlin : Humboldt-Universität zu Berlin, 2002. http://d-nb.info/1207621250/34.

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Ivashchuk, S. I. "Triglycerides level as a risk factor of the edematous pancreatitis development from the position of the genes IL-4 (RS 2243250), TNF-α (G-308A), PRSS1 (R122H) and CFTR (delF508C) polymorphism". Thesis, БДМУ, 2021. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18631.

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Cetindis, Mirjam [Verfasser], Ilka Verena [Akademischer Betreuer] Ott, and Heribert [Akademischer Betreuer] Schunkert. "Durch G-CSF mobilisierte CD34+-Progenitorzellen im akuten Myokardinfarkt zeigen eine verminderte Expression von LFA-1, VLA-4 und CXCR4 / Mirjam Cetindis. Gutachter: Heribert Schunkert ; Ilka Verena Ott. Betreuer: Ilka Verena Ott." München : Universitätsbibliothek der TU München, 2014. http://d-nb.info/1049783336/34.

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Bodenstein, Johannes. "Antagonism by selected classical irreversible competitive antagonists : an investigation into the proposed non-specific mechanisms involved / Johannes Bodenstein." Thesis, North-West University, 2003. http://hdl.handle.net/10394/92.

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Many irreversible antagonists are known to bind irreversibly to pharmacological receptors. However, few studies suggest that these irreversible antagonists may also display irreversible non-specific antagonism by binding irreversibly to non-syntopic binding sites on the receptor macromolecule, whereby they modulate the signal transduction of these receptors or reduce the agonist binding affmity. The aim of this study was to investigate whether the classical irreversible antagonists phenoxybenzamine, benextramine and 4-DAMP mustard display irreversible nonspecific antagonism at various G protei

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39

Trakadis, John. "The vervet regulator of G protein signaling 4 (RGS4) gene, a candidate gene for quantifiable behavioral dimensions associated with psychopathology : sequence, bioinformatic analysis, and association study of a novel polymorphism with social isolation." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84101.

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Regulators of G-protein coupled signaling (RGS) accelerate GTP hydrolysis and consequently influence signal termination. The RGS-4 gene has recently been reported to be implicated in a wide range of neuropsychiatric disorders including schizophrenia, Alzheimer's disease and addictions.<br>In this study, the vervet RGS-4 gene was sequenced on a CEQ 8000 genetic analysis system (Beckman Coulter) and characterized using molecular and bioinformatic tools. The obtained vervet sequence overall showed 95.3% sequence identity with the human RGS4 gene.<br>Thereafter, SNPs in the region encompass

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Babady, Mehran [Verfasser], Pedro [Gutachter] Faustmann, and Claus G. [Gutachter] Haase. "Untersuchung des Konvulsivums Pentylentetrazol sowie der Antikonvulsiva Levetiracetam und Valproinsäure hinsichtlich ihrer Einflüsse auf die Aquaporin 4-Expression an einem in vitro Astrozyten/Mikroglia-Zellkulturmodell / Mehran Babady ; Gutachter: Pedro Faustmann, Claus G. Haase ; Medizinische Fakultät." Bochum : Ruhr-Universität Bochum, 2018. http://d-nb.info/1171521898/34.

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Fallavena, Paulo Roberto Vargas. "Estudo das variantes polimórficas 896A>G (Asp299Gly) e 1196C>T (Thr399lle) do Toll like Receptor 4 (TLR4) e a suscetibilidade à sepse e às disfunções orgânicas em pacientes com condições críticas de saúde." Pontifícia Universidade Católica do Rio Grande do Sul, 2007. http://hdl.handle.net/10923/1364.

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Made available in DSpace on 2013-08-07T18:41:49Z (GMT). No. of bitstreams: 1 000391320-Texto+Completo-0.pdf: 471273 bytes, checksum: c2ed17923e23797f5ce8bb0432ca133d (MD5) Previous issue date: 2007<br>Objetivo: Investigar se há associação entre as variantes polimórficas 896A>G (Asp299Gly) e 1196C>T (Thr399Ile) do gene que codifica para o toll like receptor 4 (TLR4) e a suscetibilidade a sepse e às disfunções orgânicas em pacientes com condições críticas de saúde. Pacientes e Métodos: Foram selecionados para este estudo 107 pacientes com sepse secundária a infecção por bactérias Gramnegativas

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QASSOUD, DRISS. "Simulations de la reponse du detecteur a zero degre du projet d'experience 4 au g. S. I. -darmstadt (r. F. A. ). Etude du modele de fai et randrup et contribution a la resolution du detecteur." Clermont-Ferrand 2, 1990. http://www.theses.fr/1990CLF21245.

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L'etude developpee dans cette these est consacree aux simulations de la reponse du detecteur a zero degre ou mur interne (construit par le laboratoire de clermont-ferrand) qui est un element du detecteur 4 implante au g. S. I. -darmstadt (r. F. A. ); d'autre part, nous etudions le flot de matiere caracterisant l'ecoulement collectif de la matiere nucleaire dans le plan de reaction. Ces simulations sont basees sur le modele statistique de g. Fai et j. Randrup mis en uvre sous forme d'un code informatique freesco generant les particules emises lors de lma collision. Des resultats tires de ce cod

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Mikdache, Aya. "Analyse in vivo du comportement des cellules de Schwann et du rôle de rgs4 dans le développement du système nerveux périphérique chez le poisson zèbre." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS463.

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Les cellules de Schwann (CS) sont les cellules gliales myélinisantes du Système Nerveux Périphérique (SNP). Il existe une communication étroite entre ces cellules et les axones auxquels elles s’associent et ce dès les stades les plus précoces de leur développement. Elles migrent tout en se divisant le long des axones; cette division migratoire est suivie d’une deuxième division post-migratoire dans le but d’établir un ratio 1:1 avec les axones pour ensuite les myéliniser. Ce travail vise à analyser, in vivo, le comportement des CS chez le poisson zèbre au cours de leurs divisions.Nous avons re

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Fallavena, Paulo Roberto Vargas. "Estudo das variantes polim?rficas 896A>G (Asp299Gly) e 1196C>T (Thr399lle) do Toll like Receptor 4 (TLR4) e a suscetibilidade ? sepse e ?s disfun??es org?nicas em pacientes com condi??es cr?ticas de sa?de." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2007. http://tede2.pucrs.br/tede2/handle/tede/5519.

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Made available in DSpace on 2015-04-14T14:51:38Z (GMT). No. of bitstreams: 1 391320.pdf: 471273 bytes, checksum: c2ed17923e23797f5ce8bb0432ca133d (MD5) Previous issue date: 2007-05-07<br>Objetivo: Investigar se h? associa??o entre as variantes polim?rficas 896A>G (Asp299Gly) e 1196C>T (Thr399Ile) do gene que codifica para o toll like receptor 4 (TLR4) e a suscetibilidade a sepse e ?s disfun??es org?nicas em pacientes com condi??es cr?ticas de sa?de. Pacientes e M?todos: Foram selecionados para este estudo 107 pacientes com sepse secund?ria a infec??o por bact?rias Gramnegativas, internados

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Barakat, Makhzoum Abdullah. "Mise en place d'un système de transfert de gènes et de regénération de plantes in vitro pour l'étude de la régulation du métabolisme des alcaloïdes chez Catharanthus roseus (L. ) G. Don : application au promoteur de la déacétylvindoline 4-0-acétyltransférase." Tours, 2007. http://www.theses.fr/2007TOUR3802.

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Cette thèse présente la première analyse fonctionnelle du promoteur du gène de la déacétylvindoline 4-O-acétyltransférase (dat) chez Catharanthus roseus, la pervenche de Madagascar. DAT catalyse la dernière étape de la biosynthèse de la vindoline. Cet alcaloïde indolique monoterpénique est l’un des précurseurs de la vinblastine et de la vincristine, les alcaloïdes dimères anticancéreux. Ce gène s’exprime de manière cellule-spécifique dans les idioblastes et les laticifères des feuilles et des jeunes fleurs. La spécificité de l’expression exige un système différencié au niveau tissulaire et cel

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Kwant, Jan [Verfasser], and Jochen H. H. [Mitwirkender] Ehrich. "CTLA-4 single-strand Polymorphismus A/G an Position 49 in Exon 1 als Prädiktor für eine steroidfreie Posttransplantationsmedikation und akute Transplantatabstoßung / Jan Kwant. Jochen H. H. Ehrich. Zentrum Kinderheilkunde Abteilung pädiatrische Nephrologie und Stoffwechsel-Erkrankungen der Medizinischen Hochschule Hannover." Hannover : Bibliothek der Medizinischen Hochschule Hannover, 2010. http://d-nb.info/1004468822/34.

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Martinsson, Hanna-Stina. "Single cell analysis of checkpoints in G₁ /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-455-4/.

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Drwal, Veronika [Verfasser], and Thomas [Akademischer Betreuer] Wex. "Die Bedeutung der Expression der G-Protein-gekoppelten-Rezeptoren BRS 3, CCKA, CXCR 4, GHRH, GRPR, NK 1, NMBR, NT 2, PAC 1, VPAC 1 und VPAC 2 bei kolorektalen Tumoren in Abhängigkeit von Tumorstadium und Differenzierungsgrad / Veronika Drwal. Betreuer: Thomas Wex." Magdeburg : Universitätsbibliothek, 2012. http://d-nb.info/1054135525/34.

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Doberenz, Claudia Verfasser], G. [Akademischer Betreuer] Sawers, S. E. [Akademischer Betreuer] Behrens, and Gottfried [Akademischer Betreuer] [Unden. "Charaktiersierung des Formiat-Kanal-Proteins FocA aus Escherichia coli / Claudia Doberenz. Betreuer: G. Sawers ; S.-E. Behrens ; G. Unden." Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2013. http://nbn-resolving.de/urn:nbn:de:gbv:3:4-9257.

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Foy, Denis. "Sur l'élaboration de nouveaux carbonitrures : des variétés graphitiques aux structures peu compressibles." Phd thesis, Université Sciences et Technologies - Bordeaux I, 2007. http://tel.archives-ouvertes.fr/tel-00374077.

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En Chimie des Matériaux, la recherche de performances optimales pour la matière condensée a toujours été un challenge. Au début des années 90 Liu et Cohen proposèrent par des calculs ab initio, un modèle empirique permettant de calculer le module de compressibilité des matériaux covalents ainsi qu'un nouveau matériau appelé C<sub>3</sub>N<sub>4</sub>-β isostructural de Si<sub>3</sub>N<sub>4</sub>-β pouvant posséder des propriétés mécaniques proches de celles du diamant. Dès lors plusieurs autres variétés (quatre tridimensionnelles et une bidimensionnelle) furent envisagées pour ce carbonitrure

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