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Journal articles on the topic 'G. latifolium'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Ojo, F. T., O. A. Idowu, K. O. Ademolu, O. T. Adenubi, and J. O. Olukunle. "Evaluation of Anthelmintic activities of Single and Combined Extracts of <i>Picralima nitida</i> and <i>Gongronema latifolium</i> against the Gastrointestinal parasite (<i>Heligmosomoides bakeri</i>)." Nigerian Journal of Parasitology 44, no. 2 (2023): 327–37. http://dx.doi.org/10.4314/njpar.v44i2.5.

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Helminth infections are among the common infections affecting a large proportion of the world’s population, and most of these infections are generally limited to the tropics. For 27 days, anthelmintic activities of orally administered 500mg/kg per body weight of single and combined ethanol extracts of seeds of Picralima and roots of Amaranth globe were determined in vivo using Heligmosomoides bakeri, a gastrointestinal parasite of rodents. Combined extracts were administered at 500 mg/kg to H. bakeri-infected mice in ratios 1:1, 2:3, 3:2, 4:1 and 1:4 of P. nitida to G. latifolium. Albendazole

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2

Mbosowo M., Etukudo, and Osim Samuel E. "Development Indices of Gongronema latifolium Benth Domesticated in Otuoke Terrestrial Habitat, Bayelsa State, Nigeria." European Scientific Journal, ESJ 14, no. 24 (2018): 1. http://dx.doi.org/10.19044/esj.2018.v14n24p1.

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The effects of physico-chemical properties of two soil sampling locations on the proximate and mineral nutrients contents of Gongronema latifolium Benth were examined in Otuoke secondary forest habitat, in Bayelsa State, Nigeria. Leaf samples of Gongronema latifolium and soil (0-20 cm depth) samples were randomly collected from two sites in the study area. Three replicates were maintained for each treatment using randomized complete block design. The pH of 5.10 was recorded at location 1 while that of location 2 was 5.00. The contents of calcium, magnesium, sodium, phosphorus, iron, copper and

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3

Chigamezu, Godwin Delight, Wilfred Obaalologhi, and Okure Victoria. "Effect of aqueous extract of Gangronema latifolium (G. latifolium) (Utazi) on n-acetyl-para-aminophenol (acetaminophen) - induced hepatic injury on Wistar albino rats." Scientia Africana 20, no. 2 (2021): 119–25. http://dx.doi.org/10.4314/sa.v20i2.11.

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The present study investigated the effect of leaf extract of Gangronema latifolium (G. latifolium) on acetaminophen (APAP) - induced liver injury in Wistar albino rats. In this study, sixty (60) male Wistar albino rats were divided into five (5) groups of twelve (12) rats each. Animals in group 1 served as control group and received a placebo of 0.9% saline solution. Group 2 served as APAP control group, administered with 800 mg/kg body weight of APAP only. Groups 3, 4 and 5 served as the experimental groups and received oral dosage of 800 mg/kg body weight of APAP plus 150 mg/kg, 200 mg/kg an

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Ojo, F. T., O. A. Idowu, K. O. Ademolu, and J. O. Olukunle. "In vivo anthelmintic potentials of Gongronema latifolium and Picralima nitida against gastrointestinal parasite (Heligmosomoides bakeri)." Helminthologia 60, no. 4 (2023): 336–47. http://dx.doi.org/10.2478/helm-2023-0033.

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Summary Gastrointestinal parasites which are responsible for soil-transmitted helminthiases cause illness globally. The control of helminthiasis depends on mass distribution of anthelmintics which has been reported for its resistance, toxicity and low efficacy. In this study, anthelmintic potentials of Gongronema latifolium and Picralima nitida which have wide application in traditional medicine were determined in vivo using Heligmosomoides bakeri a naturally occurring gastro-intestinal parasite of rodents that is closely related to highly prevalent human nematode parasites. Extracts of P. nit

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5

Osuagwu, Olachi Lilian, Chidi Uzoma Igwe, Chiamaka Perpetua Nzebude, Onyinyechi Chijioke Njoku, and Juliet Chioma Ejiofor. "Phenolic Profile and Antioxidant Potential of Aqueous Extracts of Selected Traditional Anti-cough Plants." Journal of Drug Delivery and Therapeutics 13, no. 7 (2023): 22–29. http://dx.doi.org/10.22270/jddt.v13i7.6124.

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The recent surge in attention towards plant-based antioxidants can be attributed to their perceived advantageous impact on human health. The present study assessed the phenolic profile, antioxidant potential, and free radical scavenging ability of hot aqueous leaf extracts obtained from Vernonia amygdalina, Piper guineense, and Gongronema latifolium. High-Performance Liquid Chromatography (HPLC) was used to examine phenolic profile. Antioxidant capacity was conducted using total flavonoid content (TFC), total phenol content (TPC), total antioxidant capacity (TAC), polyphenol oxidase (PPO) acti

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Wijayanto, Andri, Ita Widowati, and Tjahjo Winanto. "Domestication of Red Seaweed (Gelidium latifolium) in Different Culture Media." ILMU KELAUTAN: Indonesian Journal of Marine Sciences 25, no. 1 (2020): 39–44. http://dx.doi.org/10.14710/ik.ijms.25.1.39-44.

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Gelidium latifolium is one of red seaweed types potentially can be developed as an industrial raw material. Since Gelidium is currently taken from ocean, the availability of seaweed from aquaculture is necessary to overcome the small number of its availability in nature. In Indonesia, G. latifolium cultivation has not been carried out so that domestication is required. The use of macro and micro nutrients in growth media is essentially needed for the domestication process. Domestication requires fast media and place for growth. The purpose of this study is to determine the growth of biomass an

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7

Okerulu, Adaobi Linda, Osah Martins Onwuka, and Godson Chukwuemeka Ajuzie. "Hepatic Enzymatic Activities of Di-Herbal Aqueous Extract of Ocimum gratissimum and Gongronema latifolium on Liver Dysfunction in Experimental Hyperglycemic Rats." Journal of International Research in Medical and Pharmaceutical Sciences 18, no. 2 (2023): 13–22. http://dx.doi.org/10.56557/jirmeps/2023/v18i28258.

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This study investigated the hepatic enzymatic activities of di-herbal aqueous extract of Ocimum gratissimum and Gongronema latifolium on liver dysfunction in experimental hyperglycemic rats. The animals were randomly assigned into; Group 1 – control, Group 2 – hyperglycemic control (diabetes induced and untreated), Group 3 – received 300 mg/kg of O. gratissimum extract, Group 4 – received 300 mg/kg of G. latifolium extract, Group 5 – received di-herbal extract of 150 mg/kg of O. gratissimum and 150 mg/kg of G. latifolium for 28 days. The results showed that experimental hyperglycemia induced l

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Ogbonna, Grace, Rabiu Magaji, and Sherif Isa. "THE EFFECTS OF METHANOLIC LEAF EXTRACT OF GONGRONEMA LATIFOLIUM ON MILK YIELD AND SOME LACTOGENIC HORMONES IN LACTATING WISTAR RATS." FUDMA JOURNAL OF SCIENCES 6, no. 2 (2022): 58–62. http://dx.doi.org/10.33003/fjs-2022-0602-771.

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Proper and exclusive breastfeeding is recommended during the early infancy stage of a child. Lactation insufficiency serves as a hinderance to this. Gongronema latifolium is an important medicinal plant known for its various therapeutic effects. The lactogenic effects of Gongronema latifolium used locally to boost lactation was investigated. Twenty Wistar dams were grouped into five groups (n=4); consisting of control group (1 ml/kg distilled water), standard drug group (metoclopramide 5 mg/kg), 200 mg /kg, 400 mg/kg and 800 mg/kg Gongronema latifolium methanolic extract groups. The pups were

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9

Egbuniwe, Maureen Ifeyinwa, Harrison Anezichukwu Ozoani, Amara Anwuchaepe Ajaghaku, Ikechukwu Sonne Mbagwu, Uchechukwu Harrison Orji, and Daniel Lotanna Ajaghaku. "Combination Interactive Effects of Gongronema latifolium Leaves and Picralima nitida Seeds Extracts on Glucose Tolerance." Biology, Medicine, & Natural Product Chemistry 12, no. 1 (2023): 259–66. http://dx.doi.org/10.14421/biomedich.2023.121.259-266.

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This study evaluated the combination interactive effects of G. latifolium leaves and P. nitida seed extracts using a metabolic glucose tolerance test. The plant samples were extracted separately using cold maceration and their acute toxicities were determined. Dose-response glucose tolerant tests of both plants were done using a 2 g/kg glucose load monitored over 0 – 1h. A 41% effect isobologram was used to determine the needed dose combinations according to the principle of Loewe’s additivity model. The glucose tolerant tests of dose pairs of the combined extracts were evaluated and their com

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10

Daniel, Ikechukwu Oraekei, Benjamin Uzodinma Chukwuka, Harrison Orji Uchechukwu, et al. "Evaluation of the anti-inflammatory, anti-ulcer and gastric histopathology activities of ethanol leaf extracts of Gongronema latifolium in diclofenac induced albino rat models." World Journal of Advanced Research and Reviews 21, no. 3 (2024): 182–91. https://doi.org/10.5281/zenodo.14050128.

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The stomach is the roomiest portion of gastrointestinal tract. It serves as a reservoir for ingested food, secrets enzymes and hydrochloric acid for digestion of foods. This study was aimed at evaluating the anti-ulcer activity of ethanol leaf extracts of <em>Gongronema latifolium</em> in diclofenac induced albino rat models. <em>G. latifolium</em> leaves powder (1600 g) was weighed and extracted by cold maceration for 72 hours in 15 L of ethanol. Qualitative phytochemical analysis and acute toxicity study of the extract were done. Anti-inflammatory activities of the extrac

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Daniel Ikechukwu Oraekei, Chukwuka Benjamin Uzodinma, Uchechukwu Harrison Orji, et al. "Evaluation of the anti-inflammatory, anti-ulcer and gastric histopathology activities of ethanol leaf extracts of Gongronema latifolium in diclofenac induced albino rat models." World Journal of Advanced Research and Reviews 21, no. 3 (2024): 182–91. http://dx.doi.org/10.30574/wjarr.2024.21.3.0624.

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The stomach is the roomiest portion of gastrointestinal tract. It serves as a reservoir for ingested food, secrets enzymes and hydrochloric acid for digestion of foods. This study was aimed at evaluating the anti-ulcer activity of ethanol leaf extracts of Gongronema latifolium in diclofenac induced albino rat models. G. latifolium leaves powder (1600 g) was weighed and extracted by cold maceration for 72 hours in 15 L of ethanol. Qualitative phytochemical analysis and acute toxicity study of the extract were done. Anti-inflammatory activities of the extract were tested on both heat and hypo to

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12

Chidozie, Vivian N., Nita Mgbemena, and Emmanuel Onah Isegbe. "Comparative Effects of Ethanolic Leaf Extracts of Gongronema latifolium Benth and Bryophyllum pinnatum (Lam.) Oken in The Management of Diabetes Mellitus in Albino Rats." Afghanistan Journal of Basic Medical Science 1, no. 1 (2023): 1–10. http://dx.doi.org/10.62134/ajbms/v1.i1.khatamuni.1.

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Introduction: Diabetes is a multi-factorial metabolic disorder characterized by hyperglycemia, which is the primary factor in preventing glucose from achieving its desired levels in patients with the condition. Hyperglycemia results from a lack of insulin secretion, inadequate insulin action or both. Materials and Methods: The comparative effects of ethanolic leaf extracts of The comparative effects of ethanolic leaf extracts of Gongronema latifolium (G. latifolium) and Bryophyllum pinnatum (B. pinnatum) on some biochemical parameters in diabetic induced albino rats were investigated. Two diff

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13

Omodamiro O.D., Alaebo P.O., Olukotun B.G., and Chikezie P.C. "Evaluation of hepatotoxicity effect of methanol leave extract of Gongronema latifolium in Albino rats." World Journal of Advanced Pharmaceutical and Life Sciences 1, no. 1 (2021): 014–22. http://dx.doi.org/10.53346/wjapls.2021.1.1.0017.

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Gongronema latifolium is highly medicinal in nature. The fundamental ingredients used for medicinal purposes are stored in the various parts of the plant such as the fruits, seeds, leaves, root and stem. This present study is aimed to evaluate the hepatotoxicity effect of methanolic leaf extract of Gongronema latifolium on albino rats. This study was divided into five groups normal control groups: received commercial rat feed and water, group 2: received 1000 mg/kg b.w. of leaf extract of Gongronema latifolium, group 3: received 500 mg/kg b.w of leaf extract of G. latifolium, group 4; received

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14

Anameze, C. I., I. O. Emmy-Egbe, L. C. Anyaegbunam, et al. "Qualitative and Quantitative Phytochemical Analysis of Gongronema latifolium Leaf Extract." IPS Journal of Applied Microbiology and Biotechnology 2, no. 1 (2023): 16–19. http://dx.doi.org/10.54117/ijamb.v2i1.10.

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Phytochemical compounds are secondary metabolites produced by plants in which some have medicinal uses. The aim of this study is to qualitatively and quantitatively analyze the phytochemical composition of G. latifolium leaf extract. Fresh and healthy leaves of the medicinal plant of G. latifolium leaf were harvested, washed thoroughly in distilled water and dried at room temperature for 7 days. The dried leaf was milled to fine powder. The pulverized plant was weighed and used for the phytochemical analysis. Based on qualitative analysis, the results show the presence of tannins, alkaloids, s

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15

Ekozin, A. A., O. B. Isola, O. C. Inetianbor, S. O. Omondiale, R.T Omojoyegbe, and T. S. Okanlawon. "Green Synthesized Iron Nanoparticles Using Gongronema latifolium Leaf Extract: Characterization, Antioxidant, and Antidiabetic Activities." GVU Journal of Science, Health and Technology 9, no. 1 (2024): 137–49. https://doi.org/10.5281/zenodo.13296786.

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ABSTRACTGreen nanoparticles are derived from natural sources possessing unique properties for biomedical applications.Inhibition of key enzymes (-amylase and -glucosidase) involved in the digestion of starch and protection againstfree radicals and lipid peroxidation could be part of the therapeutic approach towards the management ofhyperglycemia. The study was carried out to synthesize and characterize Iron Oxide nanoparticles coatedwith ethanolic leaf extracts of Gongronema latifolium (Gl-FeONPs) using highly advanced techniques for itsuse as antioxidant and antidiabetic. The study compared t

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16

S, Karupusamy. "REPRODUCTIVE BIOLOGY OF GNETUM LATIFOLIUM BLUME (GNETALES) IN TAMIL NADU." Kongunadu Research Journal 3, no. 2 (2016): 75–78. http://dx.doi.org/10.26524/krj150.

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The reproductive biology of Gnetum latifolium Blume studied in four different forest sites of Tamil Nadu. G. latifolium reported to have dioecious plants with less number male population in all the selected areas. Entamophilous cues observed with common anaemophily and pollinator may be flies. Pollination dropsare also reported in young ovules. The seed maturation and germination frequency observed with very low frequency in all the selected population whereas in high number of abortive ovules reported in Western Ghats.

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17

Eboh, Abraham Sisein, Owabhel Faith Robert, Azibanasamesa Dumaro Charles Owaba, and Ebizimor Wodu. "GC-MS Analysis of Medicinal Compounds and Reactive Oxygen Species Scavenging Properties of Gongronema Latifolium (Utazi) n-Hexane Extract." Pharmaceutical and Chemical Journal 10, no. 1 (2023): 37–42. https://doi.org/10.5281/zenodo.13983560.

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<em>Gongronema latifolium </em>(Amaranth globe) is popularly known for its nutritional and health promoting values. This plant is widely found in the southern part of Nigeria and is used in local dishes and also for Medicinal purposes. In this project the essential Medicinal and nutritive compounds were detected using GC-MS analysis. The leaves of <em>Gongronema latifolium </em>were dried and extracted with n-hexane. The dry paste was subjected to GC-MS analysis. Various Medicinal and nutritive compounds were detected which included 1,5-diisopropyl-2,3-dimethylcyclohexane, 2,5-bis(1-methyl pro

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Kayode, Dasofunjo, Timothy Francisca M, Eyam John A, et al. "Haematinic and immunomodulatory effects of leaf extract of gongronema latifolium following the onslaught of mucosa ulceration in wistar rats." Global Journal of Pure and Applied Sciences 29, no. 1 (2023): 49–54. http://dx.doi.org/10.4314/gjpas.v29i1.6.

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Helicobacter pylori (H. pylori) infection is a global public health problem; a higher burden of the infection was reported in developing countries including Nigeria and Cameroun. It has been associated with several gastrointestinal diseases, and recently implicated with some haematological abnormalities. This research was carried out to determine the effect of ethanol extract of Gongronema latifolium on haematological parameters of ulcerated Wistar rats.. The experiment was carried out on thirty-six (36) healthy male Wistar rats of weight ranges from (180-200) g. The rats were divide into six

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Tia, Etienne V., Augustin A. Adima, Sébastien L. Niamké, et al. "Chemical Composition and Insecticidal Activity of Essential oils of two Aromatic plants from Ivory Coast against Bemisia tabaci G. (Hemiptera: Aleyrodidae)." Natural Product Communications 6, no. 8 (2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600835.

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Essential oils of aromatic plants with insecticidal properties are nowadays considered as alternative insecticides to protect cultures from attack by insect pest. The aims of the present work were to evaluate the toxicity of the essential oils vapors of two aromatic plants ( Lippia multiflora Mold. and Aframomum latifolium K. Schum) against Bemisia tabaci and to characterize their chemical composition. The highest fumigant toxicity against B. tabaci adults was observed with the L. multiflora oil: by exposure to 0.4 μL/L air, the lethal time inducing 90% mortality (LT90) was below 2 hours for t

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Prasedya, Eka Sunarwidhi, Nur Ardiana, Hasriaton Padmi, et al. "The Antiproliferative and Apoptosis-Inducing Effects of the Red Macroalgae Gelidium latifolium Extract against Melanoma Cells." Molecules 26, no. 21 (2021): 6568. http://dx.doi.org/10.3390/molecules26216568.

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The red macroalga Gelidium latifolium is widely distributed in the coastal areas of Indonesia. However, current knowledge on its potential biological activities is still limited. In this study, we investigated the potential bioactive compounds in Gelidium latifolium ethanol extract (GLE), and its cytotoxic effects against the murine B16-F10 melanoma cell line. GLE shows high total phenolic content (107.06 ± 17.42 mg GAE/g) and total flavonoid content (151.77 ± 3.45 mg QE/g), which potentially contribute to its potential antioxidant activity (DPPH = 650.42 ± 2.01 µg/mL; ABTS = 557.01 ± 1.94 µg/

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Chinedu, Imo, O. Uhegbu Friday, Nkeiruka G. Ifeanacho, Otito Egbeigwe, and A. S. Ezekwe. "Biochemical and histological changes associated with methanolic leaf extract of Gongronema latifolium in acetaminophen-induced hepatic toxicity in wistar albino rats." International Journal of Biomolecules and Biomedicine (IJBB) 4, no. 2 (2014): 1–7. https://doi.org/10.5281/zenodo.8303762.

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This study examined the biochemical and histological changes associated with methanolic leaf extract of <em>Gongronema latifolium</em> in acetaminophen-induced hepatic toxicity in wistar albino rats. The serum liver enzymesALT, AST and ALP decreased significantly (p<0.05) in the test animals treated with 600mg/kg of the leaf extract. Protein concentration increased significantly (p<0.05) in the test animals treated with 600mg/kg of the leaf extract.The effect of the <em>G. latifolium</em> leaf extract seems to be dose dependent on the liver enzymes and protein concent

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Nwakpa, J. N., E. E. Oti, and M. U. Agim. "Toxicity of aquaeous leaf extracts of Gongronema latifolium on behaviourial and haematological characteristics of Clarias gariepinus (Burchell, 1822) juveniles." Journal of Aquatic Sciences 35, no. 1 (2020): 19–28. http://dx.doi.org/10.4314/jas.v35i1.3.

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A static bioassay experiment was set up to investigate effects of acute (96-hrLC50) concentrations of aqueous leaf extracts of Gongronema latifolium on behaviourial and haematological characteristics of Clarias gariepinus (Burchell, 1822) juveniles. Evaluation of toxicity of leaf extracts at concentrations of: 0, 10, 25, 50, 75, and 100mg/l was done at various time intervals on the fish. A total of 180 catfish juveniles with average initial weight of 8.37±1.36g and total length of 12.10±2.45cm were used. The fish were distributed among the treatments on complete randomized design. Each treatme

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Adeniran, Adedapo Adedayo, Emmanuel Adeyanju, and Nneka Kingslena Okeke. "Anatomical characterization and physicochemical standardization of Gongronema latifolium Benth. (Apocynaceae)." Journal of Pharmacy & Bioresources 19, no. 1 (2022): 16–23. http://dx.doi.org/10.4314/jpb.v19i1.3.

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Gongronema latifolium Benth belongs to the family Apocynaceae. Generally, the leaves and stems of G. latifolium are used as medicine and spices for sauces, soups and salads in Southern Nigeria. In view of its medicinal uses, the present study aimed at documenting anatomical characters and physicochemical properties for its standardization. The leaf epidermis, transverse section of the midrib, petiole and stem were prepared using standard procedures. Physicochemical properties of the powdered plant were conducted following standard methods. The leaf epidermal layer revealed anomocytic stomata,

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EGBUCHUA, Collins, and Emmanuel Chukudinife ENUJEKE. "GROWTH RESPONSE OF GONGRONEMA LATIFOLIUM (AMARANTH GLOBE) TO SOURCES AND RATES OF ORGANIC MANURES IN AN ACID SOIL ENVIRONMENT OF TROPICAL REGIONS." International Journal of Research -GRANTHAALAYAH 9, no. 5 (2021): 145–56. http://dx.doi.org/10.29121/granthaalayah.v9.i5.2021.3916.

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A field potted experiment was carried out in Asaba area of Delta State, Nigeria to evaluate sources and rates of organic manures (poultry and farmyard) on growth responses of Gongronema latifolium in an acid soil environment. It was a factorial experiment laid out in a randomized complete block design replicated 3 times. Data on plant height, number of leaves/branches, leaf area and stem girth were collected at 3, 5, 7, 9, 11 and 13 Weeks after sowing (WAS) and subjected to analysis of variance. The results that the effects on growth parameters of the crop were not significant and that higher

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Ekong, Moses B., Aniekan I. Peter, and Ubong U. Ekpene. "Co-administration of Rauwolfia vomitoria with Gongronema latifolium or Vernonia amygdalina on spatial learning, memory, and some bio-molecules." Asian Journal of Medical Sciences 7, no. 1 (2015): 82–87. http://dx.doi.org/10.3126/ajms.v7i1.11156.

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Background: Rauwolfia vomitoria is a plant with sedative properties found useful in the management of psychotic disorders, with adverse effects being reported on its use in different brain areas.Aims and Objectives: To investigate the acute effect of combination of Rauwolfia vomitoria with either Gongronema latifolium or Vernonia amygdalina on spatial learning and memory, and some bio-molecules in rats.Materials and Methods: 24 adult male Wistar rats weighing between 220 g - 300 g were equally divided into four groups (1-4). Group 1 animals were the control treated with 0.5 ml of Tween 20. Gro

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Mansour, Abdallah Tageldein, Ahmed E. Alprol, Khamael M. Abualnaja, Hossam S. El-Beltagi, Khaled M. A. Ramadan, and Mohamed Ashour. "Dried Brown Seaweed’s Phytoremediation Potential for Methylene Blue Dye Removal from Aquatic Environments." Polymers 14, no. 7 (2022): 1375. http://dx.doi.org/10.3390/polym14071375.

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The dried form of the brown seaweed Sargassum latifolium was tested for its ability to remove toxic Methylene Blue Dye (MBD) ions from aqueous synthetic solutions and industrial wastewater effluents. In a batch adsorption experiment, different initial concentrations of MBD (5, 10, 20, 30, and 40 mg L−1), sorbent dosages (0.025, 0.05, 0.1, 0.2, 0.3, 0.4, and 0.5 g L−1), contact time (5, 10, 15, 30, 60, 120 min), pH (3, 5, 8, 10, and 12), and temperature (30, 40, 50, 60 °C) were observed. Dried powder of S. latifolium was characterized before and after adsorption of MBD using different technique

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Osemwenkhae, Osaretin Precious, and Samuel Ifidon Ojeaburu. "Hypoglyceamic and Hepatoprotective Potentials of Dichloromethane (DCM) Fraction of Gongronema Latifolium Extract in Streptozotocin-Induced Diabetic Wistar Rats." Journal of Medical and Health Studies 5, no. 2 (2024): 76–84. http://dx.doi.org/10.32996/jmhs.2024.5.2.10.

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Diabetes is a chronic health issue with devastating but preventable consequences. The increasing proportion of the aging population, intake of calorie-dense diets, weight problems and sedentary lifestyles have been directly implicated in the increased number of diabetics globally. Furthermore, diabetes confers a huge economic burden due to its management costs, especially in low income countries. This study investigated the hypoglyceamic and hepatoprotective potentials of the dichloromethane (DCM) fraction of G. latifolium stem bark extract on some biochemical parameters in streptozotocin-indu

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Chukwudozie, Ikechukwu K., Martina C. Agbo, Kenneth O. Ugwu, and Ifeoma M. Ezeonu. "Oral Administration of Gongronema latifolium Leaf Extract Modulates Gut Microflora and Blood Glucose of Induced Diabetic Rats." Journal of Pure and Applied Microbiology 15, no. 1 (2021): 346–55. http://dx.doi.org/10.22207/jpam.15.1.29.

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Studies have suggested that modulation of gut microbiota is a viable therapeutic possibility for diabetes. This study evaluated the ability of an edible plant, Gongronema (G.) latifolium Benth (Asclepiadaceae), to modulate the gut microbiome and reduce blood glucose of alloxan-induced diabetic rats. Thirty (30) young, male, albino rats were divided into 6 groups of 5 rats each: Group 1 comprised normal rats; Groups 2 to 4, diabetic rats treated with 200, 400 and 800 mg/Kg body weight of hydro-alcoholic leaf extract, respectively; Group 5, diabetic rats treated with 0.2 mg/Kg glibenclamide (an

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Ilhami, B. T. K., A. S. Abidin, N. W. R. Martyasari, et al. "Measurement of macroalgae total carbohydrate content found in Lendang Luar coast, Lombok, Indonesia for potential sources of bioethanol." IOP Conference Series: Earth and Environmental Science 913, no. 1 (2021): 012077. http://dx.doi.org/10.1088/1755-1315/913/1/012077.

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Abstract Bioethanol is a renewable alternative energy through the process of fermenting sugar from carbohydrate sources by adding microorganisms such as yeast or bacteria. Macroalgae or known as seaweed is one of the producers in the marine environment which has a high carbohydrate content so that it can be used as raw material for bioethanol. Macroalgae contains specific carbohydrates including laminarin, mannitol, alginate, agar and polysaccharides. The high carbohydrate content indicates the ethanol content produced. The aim of the study was to initial screen total carbohydrates in red alga

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Krupina, Marina V., and Wilfried Dathe. "Occurrence of Jasmonic Acid in the Red Alga Gelidium latifolium." Zeitschrift für Naturforschung C 46, no. 11-12 (1991): 1127–29. http://dx.doi.org/10.1515/znc-1991-11-1230.

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The growth regulators (-)-jasmonic acid (JA) and its 7-isom er were identified by GC-MS in the red alga Gelidium latifolium. The ratio of JA:7-iso-JA was approximately 93:7. The endogenous level amounted to 0.7 μg JA/g fresh weight.

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Ukam, N. U., J. N. Nwangwa, and E. E. Ekpenyong. "The Effect of Ethanolic Root Extract of Gongronema Latifolium on Total Plasma Protein, Albumin and Globulin Concentration." European Journal of Food Science and Technology 13, no. 1 (2025): 15–22. https://doi.org/10.37745/ejfst.2013/vol13n11522.

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Gongronema latifolium (Utazi), a tropical plant native to Nigeria, is traditionally used for both culinary and medicinal purposes. This study examined the effects of its ethanolic root extract on plasma protein, albumin, and globulin levels in Wistar rats. Twelve rats (140–160 g, both sexes) were randomly divided into control and test groups (n=6 each). The control group received standard feed, while the test group received 200 mg/kg body weight of the extract orally for 21 days, alongside standard feed. All animals had free access to water. Blood samples collected post-treatment were analyzed

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Dasofunjo, K., and AA and Nku CI Asuk. "Evaluating the effect of ethanol leaf extract of Gongronema latifolium on some reproductive hormones of male Wistar rats." GSC Biological and Pharmaceutical Sciences 12, no. 3 (2020): 166–73. https://doi.org/10.5281/zenodo.4266024.

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This research was aimed at evaluating the effect of ethanol leaf extract of <em>Gongronema latifolium</em> on some reproductive hormones of male Wistar rats.  Eighteen (18) male Wistar rats weighing 120-200 g were divided into three (3) groups of six (6) animals each. The animals were allowed to undergo acclimatisation period for seven days before the start of the research. Animals in group A served as the control, while group B and C were administered 100 and 200 mg/kg body weight of ethanol extract of <em>G. latifolium,</em> respectively. The administration was perfo

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Ikeuba, Alexander I., and Peter C. Okafor. "Green corrosion protection for mild steel in acidic media: saponins and crude extracts of Gongronema latifolium." Pigment & Resin Technology 48, no. 1 (2019): 57–64. http://dx.doi.org/10.1108/prt-03-2018-0020.

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Purpose This paper aims to appraise the inhibitory effect of saponins extracted from Gongronema latifolium (SEGL) on mild steel in acid media. This is in a bid to conserve our environment and maintain the integrity of engineering structures and materials. Design/methodology/approach The corrosion inhibition of SEGL and ethanolic extracts of the leaves of G. latifolium (EEGL) on mild steel was studied by hydrogen evolution technique within a temperature range of 30-60°C in tetraoxosulphate (VI) acid solutions. Findings The extracts inhibit the corrosion of mild steel, and the inhibition efficie

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S., I. Okonkwo1* V. E. Mmuo2 E. C. Okafor3 V.O. Offiah4 C. K. Okonkwo5 P. O. Okwuego6 V. S. Okonkwo7 A. T. Kene-Okonkwo8. "Extraction, Fatty Acid Profile and Elemental Analysis of Gongronema latifolium (Utazi) Leaf." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 1244–56. https://doi.org/10.5281/zenodo.15020463.

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Medicinal plants are well known support for traditional medicine system that are used to mitigate human diseases. The African continent and culture have provided evidence of the efficacy of indigenously grown plants as remedies against diseases. The effectiveness of these plants are as a result of the presence of secondary metabolites. In this study, the fatty acid profile, the active components and elemental (mineral) composition of Gongronema latifolium (Utazi) leaf were evaluated. Extraction was conducted using Ultrasound and Soxhlet extractor.The isolation and elemental compositions were d

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Baba, Haruna, Oghoifor Vwioko, and Jeffrey Timikare. "Free radical scavenging activity of two edible vegetables from the Niger delta region of Nigeria." GSC Biological and Pharmaceutical Sciences 5, no. 2 (2018): 069–73. https://doi.org/10.5281/zenodo.4305384.

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Oxidative stress and diseases that have their aetiology and pathophysiology in reactive oxygen species can be prevented by medicinal plants and herbs. We undertook in this study, to investigate the free radical scavenging activity of dichloromethane (DCM) and ethanol (ETOH) extracts of <em>Lasianthera africana </em>and <em>Gongronema latifolium</em> <em>in vitro</em> using 2, 2, diphenyl-1-picrylhydrazine (DPPH). The leaves of both plants were obtained locally, washed, dried and pulverized using mechanical grinder. The powdered materials were defatted using n-hexane an

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Ede, Ede Nnamdi, Uzoma Sydney Chinedu, Okwarejesu Ugochukwu Valentine, and MBA Blessing Amarachi. "Comparative Effects of the Aqueous Extracts of Gongronema Latifolium and Tetrapleura Tetraptera on Serum Liver and Kidney Markers as well as Glucose Tolerance Test of Albino Rat." International Journal of Research and Innovation in Applied Science IX, no. IX (2024): 568–73. http://dx.doi.org/10.51584/ijrias.2024.909049.

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The study investigated the effect of aqueous extract of G. latifolum and T. tetraplura on serum liver and kidney markers as well as glucose tolerance test of albino Rat. A total of twenty five male albino rats were randomly grouped into five groups. Group 1 served as control, Group 2 and 4 received 200 and 400mg/kg G. latifolium respectively. Animals in Group 3 and 5 received 200mg/kg and 400mg/kg T. tetraplura respectively for 28days. Result for AST was significantly (P<0.05) higher in group 5 (43.000±3.033) when compared to the control group (30.400±2.158). ALT concentration was also sign

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Adeyemi-Doro, Abimbola Abiodun, Sule Ola Salawu, and Akintunde Afolabi Akindahunsi. "Effects of Gongronema latifolium Benth and Celosia argentea Linn supplemented diet on the hepatic and cardiac functions of high-fat diet-induced hyperlipidemic rats." Nutrition & Food Science 52, no. 3 (2021): 534–46. http://dx.doi.org/10.1108/nfs-03-2021-0099.

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Purpose The purpose of this study is to assess the effects of two green leafy vegetables (Gongronema latifolium and Celosia argentea) on the hepatic biomarkers [Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST)], cardiac biomarkers [Creatine Kinase (CK) and Lactate Dehydrogenase (LDH)] and histopathology of the heart of high-fat diet-induced hyperlipidemic rats, with the aim of evaluating the vegetables as functional foods. Design/methodology/approach Experimental diets consisted of Control Diet (CD), High-Fat Diet (HFD), High-Fat Diet with Blanched Celosia argentea (HCB), Hi

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Nguyen, Mai Khoa Ha, Hai Xuan Nguyen, Nhan Trung Nguyen, and Mai Thi Thanh Nguyen. "Total Polyphenol contents of An Giang medicinal plants." Science and Technology Development Journal 17, no. 2 (2014): 5–9. http://dx.doi.org/10.32508/stdj.v17i2.1309.

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Total polyphenol content of 90 medicinal plants from Seven-Mountain area, Tinh Bien district, An Giang province was determined by photometric method with Folin-Ciocalteau reagent. The results showed that 7 samples have more than 200 mg GAE g-1, 22 samples from 100 to 200 mg GAE g-1, 35 sample from 50 to 100 mg GAE g-1, and 26 samples lower 50 mg GAE g-1 respectively. Seven extracts which contained highest polyphenol were stem of Morus alba, leaves of Euphorbia thymifolia, leaves of Excoecaria cochinchinensis, stem of Combretum latifolium, bark of Anogeissus acuminata, stem of Spatholobus parvi

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Chiavegato, Ederaldo José, Imre Lajos Gridi-Papp, Julio Isao Kondo, and Dixier Marozzi Medina. "Hibridação interespecífica entre Gossmum hirsutum L. var. latifolium e G. Herbaceum L. var. africanum." Bragantia 44, no. 2 (1985): 629–43. http://dx.doi.org/10.1590/s0006-87051985000200011.

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Foi obtida, pelos autores, variabilidade genética para resistência da fibra do algodoeiro a partir da hibridação entre a espécie alotetraplóide cultivada Gossypium hirsutum L. var. latifolium Hutch. e a espécie diplóide selvagem G. herbaceum L. vai. africanum Hutch. A metodologia empregada e as características agronômicas e tecnológicas da fibra do híbrido são descritas e discutidas. Visando à duplicação do número de cromossomos da espécie diplóide, foram realizados nove tratamentos com o alcalóide colchicina, em solução aquosa e em adição com pasta de lanolina, com diferentes concentrações e

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Onwukeme, C. A., S. C. Udedi, K. K. Asogwa, N. M. Nwodo, and W. C. Ijeoma. "EVALUATION OF CHEMICAL COMPOSITION, PROXIMATE STATUS AND ANTIOXIDANT ACTIVITY OF ETHANOL EXTRACT OF Gongronema latifolium (Benth) FRUIT." Bioscientist Journal 1, no. 3 (2023): 242–55. http://dx.doi.org/10.54117/the_bioscientist.v11i3.155.

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The purpose of the study was to evaluate the chemical composition, proximate status, and antioxidant activity of ethanol extract of G. latifolium fruit. The chemical composition was determined using spectrophotometric method. Moisture, ash, lipid, and fibre contents were determined using gravimetric method, while crude protein and total carbohydrate were determined using kjeldahl and difference methods respectively. Acute toxicity study was carried out with eighteen albino rats using lorke’s method. The in vitro and in vivo antioxidant activities, reducing power and inhibition of lipid peroxid

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Quy, Nguyen Ngoc, Duong Dinh Chung, Nguyen Huynh Van Hieu, Nguyen Thi Ngoc Bich, Mai Huynh Cang, and Ngo Thi Cam Quyen. "Preliminary Chemical, Total Phenolic Content, Flavonoid Content, and Antioxidant Activity of some Plants Used in Vietnam Folk Medicine." Materials Science Forum 1048 (January 4, 2022): 429–36. http://dx.doi.org/10.4028/www.scientific.net/msf.1048.429.

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Crinum latifolium , Eclipta prostrata , Ocimum gratissimum , Phyllanthus urinar ia and Streptocaulon juventas have been used in Vietnam traditional medicine practices for anti-inflammatory, anti-cancer effects and antioxidant activities since prehistoric times. Ethanol and aqueous extracts from five medicinal herbs were evaluated for their antioxidative, free radical scavenging activities and phytochemical screening. Research results showed that these medicinal herbs all had rich chemical composition, such as alkaloids, coumarins, flavonoids, phenols, etc. Among ten extracts, C.latifolium etha

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Kozhantayeva, Akmaral, Nurgul Tursynova, Ainagul Kolpek, et al. "Phytochemical Profiling, Antioxidant and Antimicrobial Potentials of Ethanol and Ethyl Acetate Extracts of Chamaenerion latifolium L." Pharmaceuticals 17, no. 8 (2024): 996. http://dx.doi.org/10.3390/ph17080996.

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The study investigates the phytochemical profile, antioxidant capacity, and antimicrobial activities of ethanol (ChL-EtOH) and ethyl acetate (ChL-EtOAc) extracts from Chamaenerion latifolium L. (ChL) harvested in Kazakhstan. The ChL-EtOH extract exhibited higher total phenolic (267.48 ± 3.44 mg GAE/g DE) and flavonoid content (24.18 ± 1.06 mg QE/g DE) compared to ChL-EtOAc. HPLC-UV-ESI/MS identified key phenolic acids and flavonoids, including gallic acid, chlorogenic acid, and quercetin 3-glucoside. FT-IR analysis confirmed the presence of characteristic functional groups. Antioxidant assays

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Agwaramgbo, Amanze, Emmanuel Emeka Ilodigwe, Daniel Lotanna Ajaghaku, Maureen Ugochukwu Onuorah, and Sonne Ikechukwu Mbagwu. "Evaluation of Antioxidant, Immunomodulatory Activities, and Safety of Ethanol Extract and Fractions of Gongronema latifolium Fruit." International Scholarly Research Notices 2014 (October 29, 2014): 1–10. http://dx.doi.org/10.1155/2014/695272.

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Gongronema latifolium fruit has wide application in ethnomedicine, especially in maintaining healthy living and general body healing. We therefore investigated the antioxidant, immunomodulatory activities, and safety of its ethanol extract and fractions. The in vitro antioxidant activities of the extract and fractions were determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) test while in vivo activities were determined using carbon tetrachloride (CCL4) induced oxidative stress. Cell and humoral mediated immune responses were also evaluated together with toxicity studies. The extract, ethyl a

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Ikwuemesi, J. C., O. E. Irozuru, and I. J. Okwu. "Growth performances, nutrient utilization and haematology of Clarias gariepinus juveniles fed varying concentrations of Gongronema latifolium leaf extracts." Journal of Aquatic Sciences 34, no. 2 (2020): 97–105. http://dx.doi.org/10.4314/jas.v34i2.12.

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There had been growing interest in the use of extracts from different plants species to boost fish production. In this study Gongronema latifolium leaf extract was supplemented in a commercial diet of Clarias gariepinus juveniles at varying concentrations of 0.5g (T2), 1.0g (T3) and 1.5g (T4) per kg of feed while the control (T1) had no leaf extract. They were fed for 8weeks while growth performance and haematological data were collected and analysed. Proximate composition of the fish flesh was carried out after the feeding trials. The initial mean weight ranged between 9.0±0.5 to 9.0±0.7g, th

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Gabriel Otu Ujong, Justin Atiang Beshel, Idara Asuquo Okon, and Daniel Udofia Owu. "Anti-inflammatory potentials of ethanolic leaf extract of Gongronema latifolium in streptozotocin induced diabetic rats." World Journal of Biology Pharmacy and Health Sciences 11, no. 1 (2022): 077–84. http://dx.doi.org/10.30574/wjbphs.2022.11.1.0109.

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Introduction: Inflammation due to diabetes mellitus has been understudied. Gongronema latifolium (GL) is reported to have anti-inflammatory potentials. This work was designed to evaluate the effect of ethanolic leaf extract of Gongronema latifolium on some inflammatory markers in Streptozotocin (STZ)-induced diabetic rats. Materials and methods: 40 Wistar rats of both sexes (150 g-200 g) were divided into 5 groups of eight (8) rats each. Group 1; control received normal saline placebo orally. Group 2; GL only received 200 mg/kg of GL orally. Group 3 DM only received 65 mg/kg bw of STZ intraper

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Gabriel, Otu Ujong, Atiang Beshel Justin, Asuquo Okon Idara, and Udofia Owu Daniel. "Anti-inflammatory potentials of ethanolic leaf extract of Gongronema latifolium in streptozotocin induced diabetic rats." World Journal of Biology Pharmacy and Health Sciences 11, no. 1 (2022): 077–84. https://doi.org/10.5281/zenodo.6966795.

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<strong>Introduction:</strong> Inflammation due to diabetes mellitus has been understudied. <em>Gongronema latifolium </em>(GL) is reported to have anti-inflammatory potentials. This work was designed to evaluate the effect of ethanolic leaf extract of <em>Gongronema latifolium</em> on some inflammatory markers in Streptozotocin (STZ)-induced diabetic rats. <strong>Materials and methods:</strong> 40 Wistar rats of both sexes (150 g-200 g) were divided into 5 groups of eight (8) rats each. Group 1; control received normal saline placebo orally. Group 2; GL only rec

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Zhang, Shulin, Yaling Cai, Jinggong Guo, et al. "Genotyping-by-Sequencing of Gossypium hirsutum Races and Cultivars Uncovers Novel Patterns of Genetic Relationships and Domestication Footprints." Evolutionary Bioinformatics 15 (January 2019): 117693431988994. http://dx.doi.org/10.1177/1176934319889948.

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Determining the genetic rearrangement and domestication footprints in Gossypium hirsutum cultivars and primitive race genotypes are essential for effective gene conservation efforts and the development of advanced breeding molecular markers for marker-assisted breeding. In this study, 94 accessions representing the 7 primitive races of G hirsutum, along with 9 G hirsutum and 12 Gossypium barbadense cultivated accessions were evaluated. The genotyping-by-sequencing (GBS) approach was employed and 146 558 single nucleotide polymorphisms (SNP) were generated. Distinct SNP signatures were identifi

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J.C., Okpala, and Ifedilichukwu H.N. "Effects of n-butanol fraction of Gongronema latifolium leave extract on some kidney function and histological parameters in CCl4-induced oxidative damage in Wistar albino rats." JOURNAL OF ADVANCES IN BIOTECHNOLOGY 2, no. 2 (2012): 119–31. http://dx.doi.org/10.24297/jbt.v2i2.1713.

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Effects of n-butanol fraction of Gongronema latifolium leave extract on some kidney function and histological parameters in (CCl4) carbon tetrachloride-induced oxidative damage in Wistar albino rats were assessed. Fifty-four (54) Wistar albino rats were divided into treatment and LD50 groups. The treatment group was further divided into seven groups of 6 animals each by the randomized random design method, each were allowed food and water ad libidium. Group A (normal control) was given feed and water, Group B (vehicle control) was injected with olive oil intraperitoneally, while the rest group

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Safiullina, Asiya K., Dilrabo K. Ernazarova, Ozod S. Turaev, et al. "Genetic Diversity and Subspecific Races of Upland Cotton (Gossypium hirsutum L.)." Genes 15, no. 12 (2024): 1533. http://dx.doi.org/10.3390/genes15121533.

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Background/Objectives: The classification and phylogenetic relationships of Gossypium hirsutum L. landraces, despite their proximity to southern Mexico, remain unresolved. This study aimed to clarify these relationships using SSR markers and hybridization methods, focusing on subspecies and race differentiation within G. hirsutum L. Methods: Seventy polymorphic SSR markers (out of 177 tested) were used to analyze 141 alleles and calculate genetic distances among accessions. Phylogenetic relationships were determined using MEGA software (version 11.0.13) and visualized in a phylogenetic tree. A

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Nduohosewo, Idongesit S., and Moses B. Ekong. "Murine’s amygdala microstructure and elevated plus maze activities following R. vomitoria root bark and G. latifolium leaf extracts administration." Anatomical Science International 95, no. 3 (2020): 342–55. http://dx.doi.org/10.1007/s12565-020-00527-1.

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