Relevant bibliographies by topics / G-SYNUCLEIN

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  1. Journal articles
  2. Dissertations / Theses
  3. Conference papers

Academic literature on the topic 'G-SYNUCLEIN'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "G-SYNUCLEIN"

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Chen, Chiung-Mei, Chien-Yu Yen, Wan-Ling Chen, et al. "Pathomechanism Characterization and Potential Therapeutics Identification for Parkinson’s Disease Targeting Neuroinflammation." International Journal of Molecular Sciences 22, no. 3 (2021): 1062. http://dx.doi.org/10.3390/ijms22031062.

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Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by the loss of dopaminergic (DAergic) neurons and the presence of α-synuclein-containing Lewy bodies. The unstructured α-synuclein forms insoluble fibrils and aggregates that result in increased reactive oxygen species (ROS) and cellular toxicity in PD. Neuroinflammation engaged by microglia actively contributes to the pathogenesis of PD. In this study, we showed that VB-037 (a quinoline compound), glycyrrhetic acid (a pentacyclic triterpenoid), Glycyrrhiza inflata (G. inflata, a Chinese herbal medicine), and Shaoyao
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Barinova, K. V., A. K. Melnikova, E. V. Schmalhausen, and V. I. Muronetz. "A rational approach to obtaining high-specific polyclonal antibodies against recombinant alpha-synuclein." Biomeditsinskaya Khimiya 64, no. 3 (2018): 276–82. http://dx.doi.org/10.18097/pbmc20186403276.

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The approach for the quick and efficient production ofpolyclonal antibodies tothe target antigen alpha-synuclein has been proposed. Two methods have been employed to purify specific rabbit polyclonal antibodies against recombinant human alpha-synuclein, produced by subcutaneous immunization with complete Freund's adjuvant. It was shown that purification on CNBr-activated Sepharose with immobilized alpha-synuclein resulted in antibody preparation with rabbit serum histidine-rich glycoprotein as a contaminant. Two-stage antibody purification procedure first on Sepharose with immobilized protein
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Büttner, Sabrina, Lukas Habernig, Filomena Broeskamp та ін. "Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease". EMBO Journal 32, № 23 (2013): 3041–54. http://dx.doi.org/10.1038/emboj.2013.228.

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Soukup, Viktor, Marta Kalousová, Otakar Capoun, et al. "Panel of Urinary Diagnostic Markers for Non-Invasive Detection of Primary and Recurrent Urothelial Urinary Bladder Carcinoma." Urologia Internationalis 95, no. 1 (2015): 56–64. http://dx.doi.org/10.1159/000368166.

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Objectives: To determine the combination of urinary protein markers for noninvasive detection of primary and recurrent urothelial bladder carcinomas. Methods: Urinary concentrations of 27 biomarkers (NSE, ATT, AFABP, Resistin, Midkine, Clusterin, Uromodulin, ZAG2, HSP27, HSP 60, NCAM1/CD56, Angiogenin, Calreticulin, Chromogranin A, CEACAM1, CXCL1, IL13Ra2, Progranulin, VEGFA, CarbAnhydIX, Annexin-V, TIM4, Galectin1, Cystatin B, Synuclein G, ApoA1 and ApoA2) were assessed by enzyme-linked immunosorbent assay or by electrochemiluminiscence immunoassay. Results: During the primary diagnostics, a
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Tripodi, Farida, Ermelinda Falletta, Manuela Leri, et al. "Anti-Aging and Neuroprotective Properties of Grifola frondosa and Hericium erinaceus Extracts." Nutrients 14, no. 20 (2022): 4368. http://dx.doi.org/10.3390/nu14204368.

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Nutrition has relevant consequences for human health and increasing pieces of evidence indicate that medicinal mushrooms have several beneficial effects. One of the main issues in Western countries is represented by the challenges of aging and age-related diseases, such as neurodegenerative disorders. Among these, Parkinson’s disease (PD) affects 10 million people worldwide and is associated with α-synuclein misfolding, also found in other pathologies collectively called synucleinopathies. Here, we show that aqueous extracts of two edible mushrooms, Grifola frondosa and Hericium erinaceus, rep
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Yabuki, Yasushi, Kohei Maeda, Tomohiro Mizobata, Yasushi Kawata, Sefan Asamitsu та Norifumi Shioda. "RNA G-quadruplexes accelerate liquid-to-solid transition of α-synuclein." Proceedings for Annual Meeting of The Japanese Pharmacological Society 94 (2021): 2—O—B2–4. http://dx.doi.org/10.1254/jpssuppl.94.0_2-o-b2-4.

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Golebiewska, Urszula, Yuanjian Guo, Narindra Khalikaprasad, Cassandra Zurawsky, V. Siddhartha Yerramilli та Suzanne Scarlata. "γ-Synuclein Interacts with Phospholipase Cβ2 to Modulate G Protein Activation". PLoS ONE 7, № 8 (2012): e41067. http://dx.doi.org/10.1371/journal.pone.0041067.

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Stefaniuk, Catherine M., Quinn Ostrom, Jill Barnholtz-Sloan, Joseph Willis та Robert W. Maitta. "Elevation of Plasma α-Synuclein Levels Is Diagnostic of Malignant or Invasive Central Nervous System Neoplasms". Blood 126, № 23 (2015): 5597. http://dx.doi.org/10.1182/blood.v126.23.5597.5597.

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Abstract α-synuclein belongs to a family of small proteins and has been described as an important pathologic mediator of neurodegenerative diseases grouped as synucleinopathies such as Parkinson's Disease and Dementia with Lewy Bodies. It is extensively expressed in the central nervous system (CNS); however, its physiologic function is not known though it may involve mediating dopamine neurotransmitter release. Additionally, it is expressed in the hematopoietic system in erythroid precursors and megakaryocytes in bone marrow, as well as erythrocytes and platelets in peripheral blood. More impo
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9

Maeda, Kohei, Yasushi Yabuki, Sefan Asamitsu та ін. "Cellular stress-induced formation of RNA G-quadruplexes accelerates α-Synuclein aggregation". Proceedings for Annual Meeting of The Japanese Pharmacological Society 95 (2022): 1—SS—26. http://dx.doi.org/10.1254/jpssuppl.95.0_1-ss-26.

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10

Docimo, Teresa, Rita Celano, Alessia Lambiase, et al. "Exploring Influence of Production Area and Harvest Time on Specialized Metabolite Content of Glycyrrhiza glabra Leaves and Evaluation of Antioxidant and Anti-Aging Properties." Antioxidants 13, no. 1 (2024): 93. http://dx.doi.org/10.3390/antiox13010093.

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Calabrian Glycyrrhiza glabra is one of the most appreciated licorice varieties worldwide, and its leaves are emerging as a valuable source of bioactive compounds. Nevertheless, this biomass is usually discarded, and its valorization could contribute to boost the economic value of the licorice production chain. In this study, the effects of production area and harvest time on the specialized metabolite content of G. glabra leaves (GGL) and also the antioxidant and anti-aging properties are evaluated to explore the potential of this untapped resource and to select the most optimal harvesting pra
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Dissertations / Theses on the topic "G-SYNUCLEIN"

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Sadideen, Doraid, and Doraid Sadideen. "Exploring G-Protein-Coupled Receptors Regulation, Specificity and Controllability of Exosomes Release in the Neuronal Cell Line SH-SY5Y." Thesis, The University of Arizona, 2016. http://hdl.handle.net/10150/621166.

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Parkinson's disease is a neurodegenerative disease characterized by the buildup of aggregated and spread of misfolded alpha-synuclein. How the misfolded alpha-synuclein contributing to the toxicity and death of neuronal cells has been the focal point of research. The spread of alpha-synuclein has been attributed to many mechanisms, one of which is via cell-derived vesicles called exosomes. This project aims to examine the controllability of exosome release. SH-SY5Y, MCF-7 and CHO-K1 cells were transfected with dopamine receptor 3-green fluorescent protein, G-protein receptor 143 or green fluor
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2

Nagle, Michael William. "The effect of the cyclin G-associated kinase on the pathogenesis of Parkinson's disease." Thesis, 2014. https://hdl.handle.net/2144/14645.

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Parkinson's Disease (PD) is the second most common neurodegenerative disorder, clinically characterized by severe motor impairment and pathologically characterized by progressive loss of the dopaminergic neurons of the substantia nigra pars compacta (SNpc) as well as the formation of cellular aggregate deposits called Lewy Bodies. While some advances have been made in understanding the molecular underpinnings of the disorder, the molecular implications of common genetic factors increasing risk for PD have not been adequately studied. First identified by GWA studies in 2009, the GAK/DGKQ/IDUA r
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Conference papers on the topic "G-SYNUCLEIN"

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Kobayashi, Ryoko, Masanori Sawamura, Hodaka Yamakado, Masayuki Sohgawa та Minoru Noda. "A Novel Detection Method of Biomarker Molecule of α-Synuclein for Parkinson Disease by Liposome-Immobilized Cantilever Biosensor Using Self-Templating Phenomena of Prionoid Protein". У 2020 International Conference on Solid State Devices and Materials. The Japan Society of Applied Physics, 2020. http://dx.doi.org/10.7567/ssdm.2020.g-8-03.

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Journal articles
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